3,181 results match your criteria Japanese Journal of Ophthalmology [Journal]


Comparison of pretreatment measurements of anterior segment parameters in eyes with acute and chronic primary angle closure.

Jpn J Ophthalmol 2019 Jan 20. Epub 2019 Jan 20.

Department of Ophthalmology, Kobe City Eye Hospital, 2-1-8, Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.

Purpose: To compare pretreatment anterior segment parameters between eyes with acute primary angle closure (APAC) and chronic primary angle closure (CPAC), and to identify the characteristics of eyes with APAC.

Study Design: Retrospective.

Methods: We measured pretreatment anterior chamber depth (ACD), iris convexity (IC), and pupil diameter in eyes with APAC and CPAC using anterior segment optical coherence tomography. Read More

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http://dx.doi.org/10.1007/s10384-019-00651-0DOI Listing
January 2019

Three cases of acute-onset bilateral photophobia.

Jpn J Ophthalmol 2019 Jan 2. Epub 2019 Jan 2.

Department of Ophthalmology, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya, 466-8550, Japan.

Purpose: To report the findings in 3 cases of bilateral negative electroretinograms (ERGs) with acute onset of photophobia.

Study Design: Retrospective case series.

Methods: The medical charts of the 3 patients were reviewed. Read More

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http://dx.doi.org/10.1007/s10384-018-00649-0DOI Listing
January 2019
1 Read

Reproducibility and reliability of retinal and optic disc measurements obtained with swept-source optical coherence tomography in a healthy population.

Jpn J Ophthalmol 2019 Jan 2. Epub 2019 Jan 2.

Ophthalmology Department, Miguel Servet University Hospital, C/ Padre Arrupe, Consultas Externas de Oftalmología, 50009, Zaragoza, Spain.

Purpose: To analyze the reproducibility of macular and peripapillary thickness measurements, and optic nerve morphometric data obtained with Triton Optical coherence tomography (OCT) in a healthy population.

Study Design: Observational cross sectional study.

Material And Methods: A total of 108 eyes underwent evaluation using the Triton Swept Source-OCT. Read More

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http://dx.doi.org/10.1007/s10384-018-00647-2DOI Listing
January 2019

Periocular inverted follicular keratosis: a retrospective series over 17 years.

Jpn J Ophthalmol 2019 Jan 2. Epub 2019 Jan 2.

Department of Ophthalmology, Rio Hortega University Hospital, Dulzaina St. 2, 47012, Valladolid, Spain.

Purpose: To evaluate the demographic, clinical, and histopathologic characteristics of periocular inverted follicular keratosis (IFK), a very rare lesion with poorly defined characteristics.

Study Design: Retrospective case series.

Methods: We evaluated 11 patients with clinically diagnosed IFK confirmed by histologic analysis. Read More

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http://dx.doi.org/10.1007/s10384-018-00650-7DOI Listing
January 2019

Tear film change and ocular symptoms after reading printed book and electronic book: a crossover study.

Jpn J Ophthalmol 2019 Jan 2. Epub 2019 Jan 2.

Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.

Purpose: To evaluate and compare tear film changes and ocular symptoms after reading an electronic book (e-book) and a printed book.

Study Design: Clinical and experimental.

Methods: Crossover study was conducted in 30 healthy volunteers, some of whom read an e-book and others a printed book for 20 minutes and then switched the following week. Read More

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http://dx.doi.org/10.1007/s10384-018-00648-1DOI Listing
January 2019

Night-vision aid using see-through display for patients with retinitis pigmentosa.

Jpn J Ophthalmol 2019 Jan 2. Epub 2019 Jan 2.

Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Purpose: From an early stage, retinitis pigmentosa (RP) patients suffer from night blindness which causes nocturnal mobility difficulties. We created a wearable visual aid that uses a high-performance see-through display, and added a high-sensitivity camera with a complementary metal-oxide-semiconductor sensor. Here, we evaluate the device's efficacy for helping night-blindness sufferers walk in the dark. Read More

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http://dx.doi.org/10.1007/s10384-018-00644-5DOI Listing
January 2019
1 Read

Influence of irrigation dynamic pressure-assisted hydrodissection on intraocular pressure and the posterior chamber-anterior hyaloid membrane barrier during cataract surgery.

Jpn J Ophthalmol 2018 Dec 19. Epub 2018 Dec 19.

Department of Ophthalmology, School of Medicine, The Jikei University, 3-25-8 Nishishinbashi, Minato-ku, Tokyo, 105-8461, Japan.

Purpose: To evaluate the effects of irrigation dynamic pressure-assisted hydrodissection (irrigation-hydro: iH) on intraocular pressure (IOP) and the posterior chamber-anterior hyaloid membrane (PC-AHM) barrier in porcine eyes.

Study Design: Experimental.

Methods: In Experiment 1, IOP was recorded while irrigating the anterior chamber (AC), during iH, and during phacoemulsification and aspiration in 20 porcine eyes using bottle heights of 50, 70, and 90 cm. Read More

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http://link.springer.com/10.1007/s10384-018-00646-3
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http://dx.doi.org/10.1007/s10384-018-00646-3DOI Listing
December 2018
18 Reads

In vivo histology and p.L132V mutation in KRT12 gene in Japanese patients with Meesmann corneal dystrophy.

Jpn J Ophthalmol 2019 Jan 7;63(1):46-55. Epub 2018 Dec 7.

Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.

Purpose: To report genetic mutational analysis and in vivo histology of Meesmann corneal dystrophy.

Study Design: Prospective, case control study.

Methods: Six patients from three independent families with clinically diagnosed Meesmann corneal dystrophy were enrolled in this study. Read More

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http://dx.doi.org/10.1007/s10384-018-00643-6DOI Listing
January 2019
1 Read

Correlation between macular structure and function in patients with age-related macular degeneration treated with intravitreal ranibizumab: 12-month-results.

Jpn J Ophthalmol 2019 Jan 23;63(1):90-99. Epub 2018 Nov 23.

Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minami-Koshigaya, Koshigaya, Saitama, 343-8555, Japan.

Purpose: To determine the significance of the correlation between optical coherence tomographic (OCT) findings and focal macular electroretinograms (fmERG) at 12 months after beginning intravitreal injections of ranibizumab (IVR) in eyes with age-related macular degeneration (AMD).

Study Design: Prospective, clinical study.

Method: We studied 28 eyes of 28 patients with AMD treated with IVR at monthly intervals for the initial three months. Read More

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http://dx.doi.org/10.1007/s10384-018-0642-1DOI Listing
January 2019
8 Reads

The impact of disc hemorrhage studies on our understanding of glaucoma: a systematic review 50 years after the rediscovery of disc hemorrhage.

Authors:
Tetsuya Yamamoto

Jpn J Ophthalmol 2019 Jan 21;63(1):7-25. Epub 2018 Nov 21.

Department of Ophthalmology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu-shi, 501-1194, Japan.

Purpose Of Review: To trace the influence of disc hemorrhage studies on our understanding of glaucoma.

Sources: Major articles published during the last 50 years since the rediscovery of disc hemorrhage were identified. A total of 196 articles were selected from 435 articles retrieved using the keywords glaucoma and disc hemorrhage as of August 9 2018 from PubMed. Read More

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http://dx.doi.org/10.1007/s10384-018-0641-2DOI Listing
January 2019

Uveitis: contrasting the approaches in Japan and the United States.

Jpn J Ophthalmol 2019 Jan 20;63(1):1-6. Epub 2018 Nov 20.

Casey Eye Institute, Oregon Health and Sciences University, 3375 SW, Terwilliger Blvd, Portland, OR, 97239, USA.

Purpose: To compare the approaches to uveitis in Japan and the United States.

Methods: This report is based on the author's personal experience, conversations with Japanese colleagues, and a literature search using the database of the US National Library of Medicine.

Results: The frequencies of specific forms of uveitis vary between the two countries. Read More

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http://dx.doi.org/10.1007/s10384-018-0633-2DOI Listing
January 2019
6 Reads

Current status of late and recurrent intraocular lens dislocation: analysis of real-world data in Japan.

Jpn J Ophthalmol 2019 Jan 13;63(1):65-72. Epub 2018 Nov 13.

Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto, 606-8501, Japan.

Purpose: To describe relevant patient demographic characteristics and investigate the influence of known risk factors for late intraocular lens (IOL) dislocation. To explore the associations between these risk factors and the incidence of recurrent IOL dislocation.

Study Design: Retrospective cohort study. Read More

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http://link.springer.com/10.1007/s10384-018-0637-y
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http://dx.doi.org/10.1007/s10384-018-0637-yDOI Listing
January 2019
7 Reads

Prognosis after lamellar keratoplasty for limbal dermoids using preserved corneas.

Jpn J Ophthalmol 2019 Jan 12;63(1):56-64. Epub 2018 Nov 12.

Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

Purpose: To evaluate the safety and efficacy of lamellar keratoplasty using preserved donor corneas to treat limbal dermoids.

Study Design: Retrospective study.

Methods: The clinical records of 19 patients with limbal dermoids, who underwent lamellar keratoplasty using preserved corneas that were observed for more than 6 months at the Keio University School of Medicine between January, 2000 and December, 2017, were retrospectively reviewed. Read More

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http://link.springer.com/10.1007/s10384-018-0639-9
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http://dx.doi.org/10.1007/s10384-018-0639-9DOI Listing
January 2019
15 Reads

Establishment of a normative database and evaluation of the test-retest repeatability of the Spaeth/Richman contrast sensitivity test.

Jpn J Ophthalmol 2019 Jan 10;63(1):73-81. Epub 2018 Nov 10.

Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, 19107, USA.

Purpose: To evaluate the test-retest repeatability of a computer-based contrast sensitivity (CS) test, the Spaeth/Richman contrast sensitivity (SPARCS) test, and to determine the effects of age and lens status on CS in normal eyes.

Study Design: Prospective cross-sectional study.

Methods: The participants were assessed by use of the SPARCS test in each eye 3 times. Read More

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http://link.springer.com/10.1007/s10384-018-0640-3
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http://dx.doi.org/10.1007/s10384-018-0640-3DOI Listing
January 2019
13 Reads

Clinical characteristics and outcomes of open globe injuries in Japan.

Jpn J Ophthalmol 2019 Jan 8;63(1):109-118. Epub 2018 Nov 8.

Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.

Purpose: To describe the epidemiology and clinical outcomes of open globe injuries (OGIs) in Japan over 10 years, and examine preoperative factors influencing the visual prognosis after surgery.

Study Design: Retrospective, observational, multicenter case-series study.

Methods: Patients' data were entered into a computerized database for review and statistical analyses. Read More

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http://link.springer.com/10.1007/s10384-018-0638-x
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http://dx.doi.org/10.1007/s10384-018-0638-xDOI Listing
January 2019
10 Reads

The 24-month outcomes of intravitreal aflibercept combined with photodynamic therapy for polypoidal choroidal vasculopathy.

Jpn J Ophthalmol 2019 Jan 7;63(1):100-108. Epub 2018 Nov 7.

Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.

Purpose: This study was prospectively carried out to clarify the effectiveness of visual and anatomical outcomes under combination therapy of intravitreal aflibercept (IVA) and verteporfin photodynamic therapy (vPDT) in over 24 months.

Study Design: A single-arm prospective exploratory study.

Methods: Twenty-six eyes of 26 treatment naïve PCV patients were enrolled in this study. Read More

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http://link.springer.com/10.1007/s10384-018-0636-z
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http://dx.doi.org/10.1007/s10384-018-0636-zDOI Listing
January 2019
4 Reads

Scientific Reviewers.

Authors:

Jpn J Ophthalmol 2018 Nov;62(6):706-707

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http://dx.doi.org/10.1007/s10384-018-0627-0DOI Listing
November 2018

Management of presumed trematode induced granulomatous uveitis in pediatric patients.

Jpn J Ophthalmol 2019 Jan 2;63(1):119-125. Epub 2018 Nov 2.

Pathology Department, Faculty of Medicine, Sohag University, Sohâg, Egypt.

Purpose: To outline the management of newly identified trematode induced uveitis in pediatric patients STUDY DESIGN: Prospective interventional case series METHODS: Patients with distinctive uveitis were recruited to either receive steroid monotherapy or undergo surgical excision of the inflammatory lesions based on a scoring system. Outcome measures included best corrected visual acuity (BCVA), intraocular inflammatory activity, and incidence of ophthalmic complications RESULTS: 170 patients (174 eyes) were recruited. Mean age was 11. Read More

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http://link.springer.com/10.1007/s10384-018-0632-3
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http://dx.doi.org/10.1007/s10384-018-0632-3DOI Listing
January 2019
7 Reads
1.800 Impact Factor

Additive intraocular pressure-lowering effects of the Rho kinase inhibitor ripasudil in Japanese patients with various subtypes of glaucoma.

Jpn J Ophthalmol 2019 Jan 28;63(1):40-45. Epub 2018 Oct 28.

Department of Ophthalmology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655, Japan.

Purpose: The present study aimed to investigate the effectiveness of adjunctive therapy involving the Rho-associated, coiled-coil-containing protein kinase (ROCK) inhibitor ripasudil in lowering intraocular pressure (IOP) in patients with different subtypes of glaucoma, on the basis of the time of IOP measurement STUDY DESIGN: Retrospective study METHODS: In total, 58 patients who underwent adjunctive therapy with ripasudil at a single institution were included. They were classified into a primary open-angle glaucoma (POAG) group, an exfoliation glaucoma (XFG) group, and a secondary glaucoma associated with uveitis, or steroid glaucoma (SG), group. The average IOPs within 6 months before (pre-IOP) and after (post-IOP) the addition of ripasudil were compared among the 3 groups. Read More

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http://link.springer.com/10.1007/s10384-018-0635-0
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http://dx.doi.org/10.1007/s10384-018-0635-0DOI Listing
January 2019
22 Reads

Clinical features of superior segmental optic hypoplasia: hospital-based study.

Jpn J Ophthalmol 2019 Jan 26;63(1):34-39. Epub 2018 Oct 26.

Department of Ophthalmology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu-shi, 501-1194, Japan.

Purpose: To determine the clinical features of patients diagnosed with superior segmental optic hypoplasia (SSOH) and to quantitatively compare retinal nerve fiber layer (RNFL) thickness in SSOH eyes, to that in normal subjects.

Study Design: Retrospective comparative case series.

Methods: We examined the medical charts of 106 eyes of 59 patients with SSOH and 35 eyes of 35 normal subjects as controls. Read More

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http://link.springer.com/10.1007/s10384-018-0634-1
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http://dx.doi.org/10.1007/s10384-018-0634-1DOI Listing
January 2019
17 Reads

Kago-Eye2 software for semi-automated segmentation of subfoveal choroid of optical coherence tomographic images.

Jpn J Ophthalmol 2019 Jan 24;63(1):82-89. Epub 2018 Oct 24.

Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

Purpose: To determine the capabilities of the "Kago-Eye2" software to semi-automatically segment the choroid in the optical coherence tomographic (OCT) images.

Study Design: A cross-sectional, prospective study of 44 healthy volunteers.

Methods: The Kago-eye2 software was developed to detect the border between Choriocapillaris and Sattler's layer (C-S) and between Sattler's layer and Haller's layer (S-H). Read More

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http://link.springer.com/10.1007/s10384-018-0631-4
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http://dx.doi.org/10.1007/s10384-018-0631-4DOI Listing
January 2019
3 Reads

Posterior subtenon infusion of triamcinolone acetonide as adjunctive treatment to panretinal photocoagulation using pattern scan laser for diabetic retinopathy.

Jpn J Ophthalmol 2018 Nov 17;62(6):686-692. Epub 2018 Oct 17.

Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Eiheiji-cho, Yoshida-gun, Fukui, Fukui-ken, 910-1193, Japan.

Purpose: To estimate the effect of sub-Tenon's capsule triamcinolone acetonide injection (STTA) combined with panretinal photocoagulation (PRP) using pattern scan laser (PSL) for high risk non-proliferative diabetic retinopathy (NPDR), in terms of the inflammation and the progression of diabetic macular edema (DME).

Study Design: Retrospective comparative analysis.

Methods: NPDR patients who underwent PRP using PSL with (STTA+PSL group, n=24) or without (PSL group, n=19) pretreatment of STTA were enrolled. Read More

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http://link.springer.com/10.1007/s10384-018-0628-z
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http://dx.doi.org/10.1007/s10384-018-0628-zDOI Listing
November 2018
4 Reads

Comparison of recurrent esotropia and consecutive exotropia with horizontal muscle reoperation in infantile esotropia.

Jpn J Ophthalmol 2018 Nov 17;62(6):693-698. Epub 2018 Oct 17.

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Irwon-Ro 81, Gangnam-gu, Seoul, Republic of Korea.

Purpose: We investigated the clinical and demographic factors associated with horizontal muscle reoperation due to recurrent esotropia or consecutive exotropia in infantile esotropia.

Methods: One hundred forty-two patients with infantile esotropia who received at least 3 years of follow-up after their first surgery between January 2004 and December 2012 were included in this study. The patients were divided into 2 groups according to the reoperation, and the reoperation group was further subdivided into 2 groups [recurrent esotropia (RET) and consecutive exotropia (CXT)]. Read More

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http://dx.doi.org/10.1007/s10384-018-0629-yDOI Listing
November 2018

Genetic diversity and persistent colonization of Enterococcus faecalis on ocular surfaces.

Jpn J Ophthalmol 2018 Nov 15;62(6):699-705. Epub 2018 Oct 15.

Department of Ophthalmology, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi, Gunma, 371-8511, Japan.

Purpose: Enterococcus faecalis causes severe acute endophthalmitis and often leads to poor visual outcomes. Conjunctival bacterial cultures occasionally grow atypical bacteria including E. faecalis, which can potentially contribute to the development of postoperative endophthalmitis. Read More

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http://link.springer.com/10.1007/s10384-018-0630-5
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http://dx.doi.org/10.1007/s10384-018-0630-5DOI Listing
November 2018
16 Reads

Automated segmentation of en face choroidal images obtained by optical coherent tomography by machine learning.

Jpn J Ophthalmol 2018 Nov 6;62(6):643-651. Epub 2018 Oct 6.

Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

Purpose: To develop an automated method to segment the choroidal layers of en face optical coherent tomography (OCT) images by machine learning.

Study Design: A cross-sectional, prospective study of 276 eyes of 181 healthy subjects.

Methods: OCT en face images of the choroid were obtained every 2. Read More

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http://link.springer.com/10.1007/s10384-018-0625-2
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http://dx.doi.org/10.1007/s10384-018-0625-2DOI Listing
November 2018
3 Reads

Intraocular pressure and wound state immediately after long versus short clear corneal incision cataract surgery.

Jpn J Ophthalmol 2018 Nov 6;62(6):621-627. Epub 2018 Oct 6.

Hayashi Eye Hospital, 4-23-35 Hakataekimae, Hakata-ku, Fukuoka, 812-0011, Japan.

Purpose: To compare the intraocular pressure (IOP) and wound state immediately after cataract surgery for eyes with a long clear corneal incision (CCI) with those for eyes with a short CCI.

Study Design: Randomized clinical trial.

Methods: One hundred twenty-eight eyes of 128 patients scheduled for phacoemulsification were randomly assigned to undergo long (≥ 1. Read More

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http://link.springer.com/10.1007/s10384-018-0626-1
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November 2018
12 Reads

Bevacizumab dosing every 2 weeks for neovascular age-related macular degeneration refractory to monthly dosing.

Jpn J Ophthalmol 2018 Nov 29;62(6):652-658. Epub 2018 Sep 29.

Department of Ophthalmology, Meir Medical Center, Kfar Sava and the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Purpose: To evaluate intravitreal bevacizumab every 2 weeks (biweekly) in refractory neovascular age-related macular degeneration (nAMD).

Study Design: Retrospective study.

Methods: A retrospective study of consecutive nAMD patients unresponsive to monthly intravitreal anti-vascular endothelial growth factor (VEGF) switched to 3-4 biweekly injections. Read More

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http://link.springer.com/10.1007/s10384-018-0619-0
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http://dx.doi.org/10.1007/s10384-018-0619-0DOI Listing
November 2018
5 Reads

Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals.

Jpn J Ophthalmol 2019 Jan 25;63(1):26-33. Epub 2018 Sep 25.

Department of Ophthalmology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho Kita-ku, Okayama, Okayama, 700-8558, Japan.

Purpose: To investigate the visual impairment certification status in Japan.

Study Design: Observational cross-sectional study.

Methods: We asked all welfare offices throughout Japan to submit data concerning age, sex, causative diseases, and visual impairment grades for newly certified visually impaired individuals aged ≥ 18 years in the fiscal year of 2015. Read More

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http://link.springer.com/10.1007/s10384-018-0623-4
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http://dx.doi.org/10.1007/s10384-018-0623-4DOI Listing
January 2019
15 Reads

Topical non-steroidal anti-inflammatory drugs for the treatment of cystoid macular edema post Descemet's stripping automated endothelial keratoplasty.

Jpn J Ophthalmol 2018 Nov 25;62(6):615-620. Epub 2018 Sep 25.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Hirokoji-agaru, Kawaramachi-dori, Kamigyo-ku, Kyoto, 602-0841, Japan.

Purpose: To investigate the effectiveness of topical non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of cystoid macular edema (CME) post Descemet's stripping automated endothelial keratoplasty (DSAEK).

Study Design: Retrospective observational study METHODS: In this study of 334 patients who underwent DSAEK at the Baptist Eye Institute, Kyoto, Japan between July 2011 and December 2015, 18 patients with postoperative CME (determined by optical coherence tomography) treated with topical NSAIDs after the onset of CME were included.

Results: At CME onset, 17 of the 18 patients were treated with bromfenac eye drops and 1 was treated with nepafenac eye drops. Read More

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http://dx.doi.org/10.1007/s10384-018-0621-6DOI Listing
November 2018
4 Reads

Occurrence of Demodex species in patients with blepharitis and in healthy individuals: a 10-year observational study.

Jpn J Ophthalmol 2018 Nov 25;62(6):628-633. Epub 2018 Sep 25.

Department of Microbiology, Wroclaw Medical University, Chalubinskiego Street 4, 50-368, Wrocław, Poland.

Purpose: Two Demodex species (eyelash mites)-D. folliculorum and D brevis-are believed to be associated with human skin and eye diseases. However, the clinical significance of infection with Demodex species remains controversial. Read More

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http://link.springer.com/10.1007/s10384-018-0624-3
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http://dx.doi.org/10.1007/s10384-018-0624-3DOI Listing
November 2018
5 Reads

Contribution of the clock gene DEC2 to VEGF mRNA upregulation by modulation of HIF1α protein levels in hypoxic MIO-M1 cells, a human cell line of retinal glial (Müller) cells.

Jpn J Ophthalmol 2018 Nov 24;62(6):677-685. Epub 2018 Sep 24.

Department of Ophthalmology, Faculty of Medicine, Oita University, 1-1 Yufu-shi, Oita, 879-5593, Japan.

Purpose: Clock genes are components of the molecular clock. Their malfunction is thought to increase the risk of numerous diseases, including cancer. Vascular endothelial growth factor (VEGF) has a pivotal role in angiogenesis, and its expression levels are controlled by clock genes in tumor cells. Read More

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http://link.springer.com/10.1007/s10384-018-0622-5
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http://dx.doi.org/10.1007/s10384-018-0622-5DOI Listing
November 2018
4 Reads

Three dimensional neuro-retinal rim thickness and retinal nerve fiber layer thickness using high-definition optical coherence tomography for open-angle glaucoma.

Jpn J Ophthalmol 2018 Nov 18;62(6):634-642. Epub 2018 Sep 18.

Department of Ophthalmology, Seoul National University Hospital, 101, Daehak-Ro Jongno-Gu, Seoul, 03080, Republic of Korea.

Purpose: To compare the diagnostic capability of three-dimensional (3D) neuro-retinal rim thickness (NRR) with existing optic nerve head and retinal nerve fiber layer (RNFL) scan parameters using high-definition optical coherence tomography (HD-OCT).

Design: Retrospective study.

Methods: Based on the mean deviation (MD) of the Humphrey Field Analyzer (HFA), the 152 subjects were categorized into mild (MD > - 6 dB, 100), moderate (MD - 6 to - 12 dB, 26), and severe (MD < - 12 dB, 26) glaucoma. Read More

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http://link.springer.com/10.1007/s10384-018-0620-7
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http://dx.doi.org/10.1007/s10384-018-0620-7DOI Listing
November 2018
4 Reads

Infection of endotheliotropic human cytomegalovirus of trabecular meshwork cells.

Jpn J Ophthalmol 2018 Nov 6;62(6):667-676. Epub 2018 Sep 6.

Department of Ophthalmology and Visual Science, Tottori University Faculty of Medicine, 36-1 Nishicho, Yonago, 683-8504, Japan.

Purpose: Human cytomegalovirus (HCMV) infections can cause endotheliitis which is associated with an elevation in the intraocular pressure (IOP). However, the mechanism of the IOP elevation has not been established. The purpose of this study was to determine whether HCMV strains which are capable of infecting corneal endothelial cells can also replicate and induce anti-viral responses, and can reorganize the actin cytoskeleton in trabecular meshwork cells. Read More

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http://link.springer.com/10.1007/s10384-018-0618-1
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November 2018
2 Reads

Causes, background, and characteristics of binocular diplopia in the elderly.

Jpn J Ophthalmol 2018 Nov 12;62(6):659-666. Epub 2018 Aug 12.

Graduate School of Medical Sciences, Kitasato University, Sagamihara, Kanagawa, Japan.

Purpose: We evaluated the background and characteristics of elderly patients with binocular diplopia including diseases caused by abnormalities in orbital pulleys.

Study Design: Retrospective.

Methods: The participants were 236 patients aged 60 years or older who visited Kitasato University Hospital complaining of binocular diplopia. Read More

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http://link.springer.com/10.1007/s10384-018-0617-2
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http://dx.doi.org/10.1007/s10384-018-0617-2DOI Listing
November 2018
14 Reads

Effect of spectacle lenses designed to reduce relative peripheral hyperopia on myopia progression in Japanese children: a 2-year multicenter randomized controlled trial.

Jpn J Ophthalmol 2018 Sep 6;62(5):537-543. Epub 2018 Aug 6.

Department of Applied Visual Science, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Purpose: Novel spectacle lenses (MyoVision, Carl Zeiss) designed to reduce relative peripheral hyperopia have been developed and reported to be effective for preventing myopia progression in a subgroup of Chinese children. In this study we examined the efficacy of MyoVision lenses in Japanese children.

Study Design: This was a multicenter prospective randomized double-blind placebo-controlled trial. Read More

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http://dx.doi.org/10.1007/s10384-018-0616-3DOI Listing
September 2018
13 Reads

Near-infrared and short-wave autofluorescence in ocular specimens.

Jpn J Ophthalmol 2018 Sep 2;62(5):605-613. Epub 2018 Aug 2.

Department of Ophthalmology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, 960-1295, Japan.

Purpose: To determine histopathologic characteristics of near-infrared autofluorescence (NIR-AF) and short-wave autofluorescence (SW-AF) in ocular tissue.

Study Design: Retrospective study.

Methods: Unstained specimens from four enucleated eyes with uveal melanoma were prepared for evaluation by fluorescence microscopy. Read More

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http://link.springer.com/10.1007/s10384-018-0614-5
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http://dx.doi.org/10.1007/s10384-018-0614-5DOI Listing
September 2018
7 Reads

Comparison of subfoveal choroidal structures in typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.

Jpn J Ophthalmol 2018 Sep 1;62(5):576-583. Epub 2018 Aug 1.

Department of Ophthalmology, Tokyo Women's Medical University, Tokyo, Japan.

Purpose: To evaluate and compare the intrachoroidal structures of eyes with typical neovascular age-related macular degeneration (AMD) with those of eyes with polypoidal choroidal vasculopathy (PCV).

Study Design: Retrospective and comparative case series.

Methods: Eighty-four treatment-naïve eyes of 84 patients (22 women and 62 men) with typical neovascular AMD or PCV located in the subfoveal region were studied. Read More

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http://link.springer.com/10.1007/s10384-018-0615-4
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http://dx.doi.org/10.1007/s10384-018-0615-4DOI Listing
September 2018
4 Reads

Incidence of side effects of topical atropine sulfate and cyclopentolate hydrochloride for cycloplegia in Japanese children: a multicenter study.

Jpn J Ophthalmol 2018 Sep 25;62(5):531-536. Epub 2018 Jul 25.

Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan.

Purpose: To investigate the incidence rate and side effects of topical atropine sulfate and cyclopentolate hydrochloride for cycloplegia in children aged 15 years or under.

Methods: This prospective study had been conducted at 9 institutions between April 1, 2016 and March 31, 2017 in patients 15 years old or younger who received either atropine or cyclopentolate for refraction assessment. The investigation included patient's age, symptoms, and whether patients with side effects had any systemic diseases. Read More

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http://link.springer.com/10.1007/s10384-018-0612-7
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http://dx.doi.org/10.1007/s10384-018-0612-7DOI Listing
September 2018
8 Reads

Perfluorocarbon liquid-assisted membrane staining and peeling technique for macular diseases.

Jpn J Ophthalmol 2018 Sep 20;62(5):592-597. Epub 2018 Jul 20.

Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.

Purpose: A surgical technique is described that facilitates membrane peeling in patients with macular diseases by using small amounts of perfluorocarbon liquid (PFCL) and brilliant blue G (BBG) dye.

Study Design: Retrospective cohort study.

Methods: After placing about 1. Read More

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http://link.springer.com/10.1007/s10384-018-0613-6
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http://dx.doi.org/10.1007/s10384-018-0613-6DOI Listing
September 2018
5 Reads

Frequencies of human leukocyte antigen alleles and haplotypes among Japanese patients with age-related macular degeneration.

Jpn J Ophthalmol 2018 Jul 12. Epub 2018 Jul 12.

Department of Ophthalmology, Kobe City Eye Hospital, 2-1-8, Minatojima-Minamimachi, Chuo-ku, Kobe, 650-0047, Japan.

Purpose: Stem cell therapy is a potential treatment for retinal disorders. We are currently exploring treating HLA matched patients of age-related macular degeneration (AMD) by using allogenic retinal pigment epithelium cells derived from induced pluripotent stem cells (iPS-RPE) from human leukocyte antigen (HLA) homozygote donors. The purpose of this study was to investigate the frequency of HLA class I and II alleles and haplotypes in Japanese patients with AMD. Read More

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http://link.springer.com/10.1007/s10384-018-0611-8
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http://dx.doi.org/10.1007/s10384-018-0611-8DOI Listing
July 2018
7 Reads

Visual function and inner retinal structure correlations in aquaporin-4 antibody-positive optic neuritis.

Jpn J Ophthalmol 2018 Jul 11. Epub 2018 Jul 11.

Division of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Purpose: To investigate the correlation between visual function and thinning of the retinal nerve fiber layer (RNFL) and the macular ganglion cell-inner plexiform layer (GCIPL) as measured by optical coherence tomography (OCT) in eyes with aquaporin-4 IgG-positive optic neuritis (AQP4-IgG-positive ON).

Study Design: Prospective study.

Methods: Patients with a history of ON were categorized into 2 groups: the AQP4-IgG-positive group and the AQP4-IgG-negative group. Read More

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http://link.springer.com/10.1007/s10384-018-0607-4
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http://dx.doi.org/10.1007/s10384-018-0607-4DOI Listing
July 2018
7 Reads

Corneal crosslinking for keratoconus in Japanese populations: one year outcomes and a comparison between conventional and accelerated procedures.

Jpn J Ophthalmol 2018 Jul 10. Epub 2018 Jul 10.

Department of Ophthalmology, Ichikawa General Hospital, Tokyo Dental College, Chiba, Japan.

Purpose: We retrospectively investigated the efficacy of corneal crosslinking (CXL) on progressive keratoconus in a Japanese population and compared the outcomes of conventional and accelerated CXL.

Study Design: A retrospective cohort study METHODS: A total of 108 consecutive eyes in 95 patients (75 men; 21.9 ± 6. Read More

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http://link.springer.com/10.1007/s10384-018-0610-9
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http://dx.doi.org/10.1007/s10384-018-0610-9DOI Listing
July 2018
5 Reads

Changes in conjunctival-scleral thickness after strabismus surgery measured with anterior segment optical coherence tomography.

Jpn J Ophthalmol 2018 Sep 6;62(5):554-559. Epub 2018 Jul 6.

Department of Ophthalmology, Hamamatsu University Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka, Japan.

Purpose: To evaluate changes in conjunctival-scleral thickness following strabismus surgery with anterior segment optical coherence tomography (AS-OCT).

Study Design: Prospective, observational, consecutive case series.

Methods: Distances between the conjunctival epithelium and inner scleral wall were measured with AS-OCT before and 3-5 months after strabismus surgery. Read More

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http://link.springer.com/10.1007/s10384-018-0609-2
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http://dx.doi.org/10.1007/s10384-018-0609-2DOI Listing
September 2018
4 Reads

Additive effects of orthokeratology and atropine 0.01% ophthalmic solution in slowing axial elongation in children with myopia: first year results.

Jpn J Ophthalmol 2018 Sep 4;62(5):544-553. Epub 2018 Jul 4.

Department of Ophthalmology, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama-shi, Saitama, 330-8503, Japan.

Purpose: To investigate the additive effects of orthokeratology (OK) and atropine 0.01% ophthalmic solution, both of which are effective procedures to slow axial elongation in children with myopia.

Study Design: Prospective randomized clinical trial. Read More

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http://link.springer.com/10.1007/s10384-018-0608-3
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http://dx.doi.org/10.1007/s10384-018-0608-3DOI Listing
September 2018
10 Reads

Prognostic factors after aflibercept therapy for typical age-related macular degeneration and polypoidal choroidal vasculopathy.

Jpn J Ophthalmol 2018 Sep 4;62(5):584-591. Epub 2018 Jul 4.

Department of Ophthalmology, Fukushima Medical University, 1 Hikarigaoka, Fukushima, Fukushima, 960-1295, Japan.

Purpose: To determine factors predictive of visual outcomes in eyes treated with intravitreal aflibercept injections (IAIs) for typical neovascular age-related macular degeneration (AMD) or polypoidal choroidal vasculopathy (PCV).

Study Design: Retrospective, multicenter, institutional, consecutive, interventional case series.

Methods: One hundred nine eyes (107 patients) with treatment-naïve neovascular AMD at 3 university hospitals were studied. Read More

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http://dx.doi.org/10.1007/s10384-018-0605-6DOI Listing
September 2018
4 Reads

Effectiveness of real-time PCR for diagnosis and prognosis of varicella-zoster virus keratitis.

Jpn J Ophthalmol 2018 Jul 11;62(4):425-431. Epub 2018 Jun 11.

Division of Ophthalmology and Visual Science, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago Tottori, 683-8504, Japan.

Purpose: To determine the efficacy of real-time PCR for the diagnosis and prognosis of varicella-zoster virus (VZV) keratitis.

Study Design: Retrospective case series.

Methods: Patients: 545 consecutive patients with keratitis were examined to quantify copy numbers of VZV DNA by real-time PCR. Read More

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http://link.springer.com/10.1007/s10384-018-0604-7
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http://dx.doi.org/10.1007/s10384-018-0604-7DOI Listing
July 2018
24 Reads

Correction to: The National Registry of Retinoblastoma in Japan (1983-2014).

Authors:

Jpn J Ophthalmol 2018 Jun 22. Epub 2018 Jun 22.

The Committee for the National Registry of Retinoblastoma. Read More

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http://dx.doi.org/10.1007/s10384-018-0606-5DOI Listing
June 2018
1 Read

Determination of 5-fluorouracil and tegafur in tear fluid of patients treated with oral fluoropyrimidine anticancer agent, S-1.

Jpn J Ophthalmol 2018 Jun 21. Epub 2018 Jun 21.

Division for Vision Research, National Institute of Sensory Organs, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.

Purpose: To establish a method for the measurement of 5-fluorouracil (5-FU), and tegafur (FT) in tear samples from patients treated with oral fluoropyrimidine anticancer agent S-1.

Study Design: Cross-sectional study.

Methods: High performance liquid chromatographic (HPLC) method reported for plasma samples was modified for tear samples. Read More

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http://dx.doi.org/10.1007/s10384-018-0603-8DOI Listing
June 2018
17 Reads

The National Registry of Retinoblastoma in Japan (1983-2014).

Authors:

Jpn J Ophthalmol 2018 Jul 30;62(4):409-423. Epub 2018 May 30.

Purpose: To review the clinical findings of retinoblastoma recorded over a period of 32 years by the National Registry of Retinoblastoma in Japan.

Study Design: Retrospective.

Methods: We reviewed the diagnoses, clinical pictures, and treatment data recorded on a yearly basis from 1983 until 2014 by major Japanese medical facilities. Read More

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http://dx.doi.org/10.1007/s10384-018-0597-2DOI Listing
July 2018
6 Reads

Short-term effect of additional apheresis on visual acuity changes in patients with steroid-resistant optic neuritis in neuromyelitis optica spectrum disorders.

Jpn J Ophthalmol 2018 Jul 25;62(4):525-530. Epub 2018 May 25.

Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.

Purpose: To evaluate temporal changes in visual acuity in patients with steroid-resistant optic neuritis (ON) in neuromyelitis optica spectrum disorders (NMOSD) after apheresis.

Design: Retrospective observational study, clinical case series SUBJECTS AND METHODS: We reviewed the medical charts of 15 eyes of 9 consecutive patients with ON in NMOSD who underwent apheresis between March 2010 and September 2017. All patients were seropositive for anti-aquaporin 4 (AQP4) antibody and resistant to steroid pulse therapy. Read More

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http://link.springer.com/10.1007/s10384-018-0602-9
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http://dx.doi.org/10.1007/s10384-018-0602-9DOI Listing
July 2018
4 Reads