4,771 results match your criteria JPEN: Journal of Parenteral and Enteral Nutrition [Journal]


Cancer-Associated Malnutrition and CT-Defined Sarcopenia and Myosteatosis Are Endemic in Overweight and Obese Patients.

JPEN J Parenter Enteral Nutr 2019 Apr 22. Epub 2019 Apr 22.

Department of Oncology, University of Alberta, Edmonton, Alberta, Canada.

Background: Overweight/obese patients' large fat mass can mask the loss of skeletal muscle, which is associated with mortality in the oncology setting. We investigated the prevalence of computed tomography (CT)-defined sarcopenia and myosteatosis across different levels of nutrition risk assessed by the Patient-Generated Subjective Global Assessment Short Form (PG-SGA SF). We also evaluated whether the PG-SGA SF, sarcopenia, and myosteatosis were prognostic of overall survival. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1597DOI Listing

Evidence-Based Strategies and Recommendations for Preservation of Central Venous Access in Children.

JPEN J Parenter Enteral Nutr 2019 Apr 21. Epub 2019 Apr 21.

VANGUARD, Venous Access (VANGUARD) Task Force, Society of Interventional Radiology (SIR), Pittsburgh, Pennsylvania, USA.

Children with chronic illness often require prolonged or repeated venous access. They remain at high risk for venous catheter-related complications (high-risk patients), which largely derive from elective decisions during catheter insertion and continuing care. These complications result in progressive loss of the venous capital (patent and compliant venous pathways) necessary for delivery of life-preserving therapies. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jpen.1591
Publisher Site
http://dx.doi.org/10.1002/jpen.1591DOI Listing
April 2019
4 Reads

Resting Energy Expenditure Measured by Indirect Calorimetry in Obese Patients: Variation Within Different BMI Ranges.

JPEN J Parenter Enteral Nutr 2019 Apr 22. Epub 2019 Apr 22.

Nutrition Therapy Multidisciplinary Team/RJ-Clínica São Vicente, Rio de Janeiro, Brazil.

Background: The adequate provision of energy for obese patients by estimation without indirect calorimetry (IC) is challenging. The goal was to establish values of kilocalories per kilogram (kcal/kg) for patients in different ranges of body mass index (BMI [kg/m ]) comparable to resting energy expenditure (REE [kcal/kg/d]) measurements by IC.

Methods: In 63 overweight (OW) hospitalized patients with BMIs (25. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1589DOI Listing

Nutrition During Targeted Temperature Management After Cardiac Arrest: Observational Study of Neurological Outcomes and Nutrition Tolerance.

JPEN J Parenter Enteral Nutr 2019 Apr 22. Epub 2019 Apr 22.

Médecine Intensive Réanimation, University Hospital Centre, Nantes, France.

Background: Whether providing nutrition support is beneficial or deleterious during targeted temperature management (TTM) after cardiac arrest is unclear. We therefore performed a retrospective observational study to determine whether early nutrition was beneficial or deleterious during TTM.

Methods: We retrospectively studied patients admitted to our intensive care unit (ICU) between 2008 and 2014 after successfully resuscitated cardiac arrest. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1596DOI Listing

Impact of Teduglutide on Quality of Life Among Patients With Short Bowel Syndrome and Intestinal Failure.

JPEN J Parenter Enteral Nutr 2019 Apr 21. Epub 2019 Apr 21.

Department of Medical Gastroenterology, Rigshospitalet, Copenhagen, Denmark.

Background: Teduglutide reduces or eliminates parenteral support (PS) dependency in patients with short bowel syndrome (SBS). Recent post hoc analyses demonstrated that effects are correlated with baseline PS volume. We assessed the SBS-related quality-of-life (QoL) impact of teduglutide, particularly whether improvements are greater among subgroups achieving more PS volume reduction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1588DOI Listing

JPEN Journal Club 45. Cluster Randomization.

Authors:
Ronald L Koretz

JPEN J Parenter Enteral Nutr 2019 Apr 22. Epub 2019 Apr 22.

Department of Medicine, Olive View-UCLA Medical Center, David Geffen-UCLA School of Medicine, University of California, Sylmar and Los Angeles, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1598DOI Listing

RW-2018-Research Workshop: The Effect of Nutrition on Epigenetic Status, Growth, and Health.

JPEN J Parenter Enteral Nutr 2019 Apr 17. Epub 2019 Apr 17.

Department of Surgery, Division of Pediatric Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

The goal of the 2018 American Society for Parenteral and Enteral Nutrition (ASPEN) Research Workshop was to explore the influence of nutrition and dietary exposure to xenobiotics on the epigenome during critical periods in development and how these exposures influence both disease incidence and severity transgenerationally. A growing compendium of research indicates that the incidence and severity of common and costly human diseases may be influenced by dietary exposures and deficiencies that modify the epigenome. The greatest periods of vulnerability to these exposures are the periconception period and early childhood. Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/jpen.1536
Publisher Site
http://dx.doi.org/10.1002/jpen.1536DOI Listing
April 2019
1 Read

Ketoacidosis in Euglycemic Patients With Type 2 Diabetes After Abdominal Surgery.

JPEN J Parenter Enteral Nutr 2019 Apr 17. Epub 2019 Apr 17.

University of Missouri-Kansas City School of Medicine, Department of Internal Medicine, Kansas City, Missouri, USA.

Diabetic ketoacidosis is defined as hyperglycemia >250 mg/dL with metabolic acidosis of arterial pH <7.3, serum bicarbonate <18 mEq/L with positive urine and serum ketones and an anion gap >10. Euglycemic ketoacidosis has been reported in patients with type 2 diabetes and in patients with type 1 diabetes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1594DOI Listing
April 2019
1 Read

A Single Urine Sodium Measurement May Validly Estimate 24-hour Urine Sodium Excretion in Patients With an Ileostomy.

JPEN J Parenter Enteral Nutr 2019 Apr 15. Epub 2019 Apr 15.

Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.

Background: Sodium deficiency in patients with an ileostomy is associated with chronic dehydration and may be difficult to detect. We aimed to investigate if the sodium concentration in a single spot urine sample may be used as a proxy for 24-hour urine sodium excretion.

Methods: In a prospective observational study with 8 patients with an ileostomy and 8 volunteers with intact intestines, we investigated the correlations and agreements between spot urine sodium concentrations and 24-hour urine sodium excretions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1593DOI Listing

Evaluation of Oropharyngeal Dysphagia in Patients Who Underwent Percutaneous Endoscopic Gastrostomy: Stratification Risk of Pneumonia.

JPEN J Parenter Enteral Nutr 2019 Apr 14. Epub 2019 Apr 14.

Division of Pulmonary and Critical Care, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Background: Aspiration pneumonia is the most common cause of death in patients who undergo percutaneous endoscopic gastrostomy (PEG). This study aims to evaluate the severity of oropharyngeal dysphagia and predict the risk of pneumonia in such patients, using upper gastrointestinal endoscopy.

Methods: Endoscope examined the pharyngolaryngeal region in patients who underwent PEG. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1592DOI Listing
April 2019
1 Read

Systematic Review: Noninvasive Assessments of Intestinal Failure-Associated Liver Disease in the Adult Population.

JPEN J Parenter Enteral Nutr 2019 Apr 1. Epub 2019 Apr 1.

Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands.

Chronic intestinal failure (CIF) patients are at risk for developing intestinal failure-associated liver disease (IFALD), which can progress to end-stage liver disease. Liver biopsy is the current reference standard to diagnose and monitor IFALD. However, due to its associated complications, biopsy is an unattractive tool in this respect. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1524DOI Listing
April 2019
2 Reads

Impact of Gastrostomy Tube Placement on Short-Term Weight Gain in Hospitalized Premature Infants.

JPEN J Parenter Enteral Nutr 2019 Mar 25. Epub 2019 Mar 25.

Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.

Background: Gastrostomy tube (G-tube) placement is a long-term alternative to oral or nasogastric feeding for premature infants who cannot safely feed orally or need supplemental nutrition for adequate growth.

Methods: We compared daily weight changes for G-tube infants 14 and 30 days preplacement and postplacement, excluding the first 7 days post-G-tube insertion. Infants <37 weeks of gestation without major congenital anomalies and discharged from 327 United States neonatal intensive care units (2004-2013) were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1539DOI Listing
March 2019
1 Read

Essential Fatty Acid Requirements and Intravenous Lipid Emulsions.

JPEN J Parenter Enteral Nutr 2019 Mar 25. Epub 2019 Mar 25.

Baxter Healthcare Corporation, Deerfield, Illinois, USA.

Linoleic acid (LA) and α-linolenic acid (ALA) must be supplied to the human body and are therefore considered essential fatty acids. This narrative review discusses the signs, symptoms, diagnosis, prevention, and treatment of essential fatty acid deficiency (EFAD). EFAD may occur in patients with conditions that severely limit the intake, digestion, absorption, and/or metabolism of fat. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1537DOI Listing

Intravenous Fish Oil and Serum Fatty Acid Profiles in Pediatric Patients With Intestinal Failure-Associated Liver Disease.

JPEN J Parenter Enteral Nutr 2019 Mar 22. Epub 2019 Mar 22.

Division of Neonatology and Developmental Biology, Department of Pediatrics, David Geffen School of Medicine UCLA, Mattel Children's Hospital at UCLA, Los Angeles, California, USA.

Background: Intravenous fish oil (FO) treats pediatric intestinal failure-associated liver disease (IFALD). There are concerns that a lipid emulsion composed of ω-3 fatty acids will cause an essential fatty acid deficiency (EFAD). This study's objective was to quantify the risk for abnormal fatty acid concentrations in children treated with FO. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1532DOI Listing
March 2019
1 Read

Body Composition Using Air Displacement Plethysmography in Children With Intestinal Failure Receiving Long-Term Home Parenteral Nutrition.

JPEN J Parenter Enteral Nutr 2019 Mar 22. Epub 2019 Mar 22.

Department of Pediatric Gastroenterology, Erasmus Medical Center - Sophia Children's Hospital, Rotterdam, the Netherlands.

Background: Children with intestinal failure (IF) are at risk of growth failure, but little information about body composition is available. Our aim was to assess body composition using air displacement plethysmography (ADP) and relate it to clinical and growth parameters.

Methods: In this prospective descriptive observational 2-center cohort study, children aged 2-18 years receiving home parenteral nutrition (PN) for ≥6 months underwent ADP measurement. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1527DOI Listing

Tolerability and Effects of the Use of Energy-Enriched Infant Formula After Congenital Heart Surgery: A Randomized Controlled Trial.

JPEN J Parenter Enteral Nutr 2019 Mar 22. Epub 2019 Mar 22.

Hospital da Criança Santo Antônio, Porto Alegre, Brazil.

Background: Undernutrition is a common problem among children with congenital heart disease (CHD) and may lead to poorer surgical outcomes. A higher intake of energy during the postoperative period of CHD surgery seems to be associated with better outcomes. This study aimed to investigate the effect of the use of energy-enriched formula (EE-formula) compared with normocaloric formula during 30 days after CHD surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1530DOI Listing

Utilization of Intensive Care Unit Nutrition Consultation Is Associated With Reduced Mortality.

JPEN J Parenter Enteral Nutr 2019 Mar 22. Epub 2019 Mar 22.

Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.

Background: The aim of this project was to investigate the prevalence of nutrition consultation (NC) in U.S. intensive care units (ICUs) and to examine its association with patient outcomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1534DOI Listing
March 2019
1 Read

JPEN Journal Club 44. When Not to Combine Data.

Authors:
Ronald L Koretz

JPEN J Parenter Enteral Nutr 2019 Mar 22. Epub 2019 Mar 22.

Olive View-UCLA Medical Center, David Geffen-UCLA School of Medicine, Sylmar and Los Angeles, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1535DOI Listing

Feeding May Modulate the Relationship Between Systemic Inflammation, Insulin Resistance, and Poor Outcome Following Cardiopulmonary Bypass for Pediatric Cardiac Surgery.

JPEN J Parenter Enteral Nutr 2019 Mar 18. Epub 2019 Mar 18.

Labatt Family Heart Centre, Department of Critical Care Medicine, University of Toronto, Toronto Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.

Background: Hyperglycemia is common following cardiopulmonary bypass (CPB) surgery and is associated with poor outcomes, often attributed to hyperinsulinemia and an acquired state of insulin resistance. This study examined the underpinnings of hyperglycemia and the effects of nutrition on the association with inflammation and clinical outcomes.

Methods: This prospective, observational cohort study enrolled consecutive children (<18 years) undergoing CPB. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1529DOI Listing

Early Postnatal Changes of Bone Turnover Biomarkers in Very Low-Birth-Weight Neonates-The Effect of Two Parenteral Lipid Emulsions with Different Polyunsaturated Fatty Acid Content: A Randomized Double-Blind Study.

JPEN J Parenter Enteral Nutr 2019 Mar 13. Epub 2019 Mar 13.

First Department of Pediatrics, Athens University Medical School, "Aghia Sophia" Children's Hospital, Athens, Greece.

Background: ω-3 polyunsaturated fatty acids (n-3 PUFAs) are reported to have beneficial effect on bone mineral density. This study aimed to evaluate early changes of bone turnover biomarkers in very low-birth-weight (VLBW) neonates and the effect of 2 parenteral lipid emulsions (PLEs) with different PUFA composition.

Methods: This is a randomized double-blind study with parallel design. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jpen.1533
Publisher Site
http://dx.doi.org/10.1002/jpen.1533DOI Listing
March 2019
7 Reads

Determinants of Quality of Life in Patients With Intestinal Failure Receiving Long-Term Parenteral Nutrition Using the SF-36 Questionnaire: A German Single-Center Prospective Observational Study.

JPEN J Parenter Enteral Nutr 2019 Mar 13. Epub 2019 Mar 13.

Department of Hepatology and Gastroenterology, Campus Virchow-Klinikum and Campus Charité Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Background: Parenteral nutrition (PN) is a life-sustaining therapy for patients with chronic intestinal failure (IF) but inevitably has an impact on patients' quality of life (QoL). The purpose of this study was to examine multiple aspects of QoL by utilizing the standardized Short Form 36 (SF-36) health survey.

Methods: Between 2014 and 2017, a total of 90 adult patients with IF who were receiving PN were prospectively enrolled in an observational study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1531DOI Listing
March 2019
1 Read

Long-Term Use of Mixed-Oil Lipid Emulsion in Soybean Oil-Intolerant Home Parenteral Nutrition Patients.

JPEN J Parenter Enteral Nutr 2019 Mar 12. Epub 2019 Mar 12.

Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, USA.

Background: Although home parenteral nutrition (HPN) is lifesaving for patients with chronic intestinal failure (IF), long-term use can be associated with complications such as infections, metabolic abnormalities, and IF-associated liver disease (IFALD). The key to treatment of many of these complications is prevention. Guidelines recommend avoidance of overfeeding, use of oral/enteral nutrition if possible, cyclic PN, and maintaining dose of soybean oil (SO) intravenous lipid emulsion (ILE) <1 g/kg/day as preventive strategies for IFALD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1526DOI Listing
March 2019
1 Read

Bovine Colostrum Against Chemotherapy-Induced Gastrointestinal Toxicity in Children With Acute Lymphoblastic Leukemia: A Randomized, Double-Blind, Placebo-Controlled Trial.

JPEN J Parenter Enteral Nutr 2019 Mar 12. Epub 2019 Mar 12.

Department of Paediatrics and Adolescent Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Background: The toxic effect of chemotherapy on the gastrointestinal tract may lead to mucositis and is associated with the pathogenesis of other treatment-related complications. We hypothesized that nutrition supplementation with bovine colostrum, rich in bioactive factors, would ameliorate gastrointestinal toxicity and reduce the incidence of fever and infectious complications during induction treatment for childhood acute lymphoblastic leukemia (ALL).

Methods: Children with newly diagnosed ALL were included in a 2-center, randomized, double-blind, placebo-controlled clinical trial. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1528DOI Listing
March 2019
2 Reads

Parenteral Provision of Micronutrients to Adult Patients: An Expert Consensus Paper.

JPEN J Parenter Enteral Nutr 2019 Mar;43 Suppl 1:S5-S23

Faculty of Biology and Medicine, Service of Intensive Care Medicine & Burns, University of Lausanne Hospitals (CHUV), Lausanne, Switzerland.

Background: Micronutrients, an umbrella term used to collectively describe vitamins and trace elements, are essential components of nutrition. Those requiring alternative forms of nutrition support are dependent on the prescribed nutrition regimen for their micronutrient provision. The purpose of this paper is to assist clinicians to bridge the gap between the available guidelines' recommendations and their practical application in the provision of micronutrients via the parenteral route to adult patients. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jpen.1525
Publisher Site
http://dx.doi.org/10.1002/jpen.1525DOI Listing
March 2019
26 Reads

Ethanol Lock Therapy for the Prevention of Nontunneled Catheter-Related Bloodstream Infection in Pediatric Patients.

JPEN J Parenter Enteral Nutr 2019 Feb 17. Epub 2019 Feb 17.

Division of Anesthesiology and Postgraduate Program in Palliative Care, IMIP, Recife, Pernambuco, Brazil.

Background: Ethanol lock therapy (ELT) has been reported as being effective in preventing central line-associated bloodstream infection (CLABSI) in tunneled (or long-term) central venous catheters (CVCs). To the best of our knowledge, no studies have evaluated this therapy in relation to nontunneled (or short-term) CVCs.

Objective: To evaluate the effectiveness of ELT in preventing CLABSI in nontunneled CVC in pediatric patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1508DOI Listing
February 2019

Vitamin D Supplementation in Mechanically Ventilated Patients in the Medical Intensive Care Unit.

JPEN J Parenter Enteral Nutr 2019 Feb 12. Epub 2019 Feb 12.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Vermont Medical Center and Larner College of Medicine, Burlington, Vermont, USA.

Background: The utility of vitamin D (VITD) supplementation during critical illness and whether it may alter outcomes, including mortality and ventilator-free days, is unclear. We performed a retrospective cohort study in a generalizable population to investigate this question.

Methods: We included all mechanically ventilated adults admitted to the medical intensive care unit (ICU) service at a tertiary center from 2009 to 2012 who were in the ICU for at least 72 hours. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1520DOI Listing
February 2019

Use of Concentrated Parenteral Nutrition Solutions Is Associated With Improved Nutrient Intakes and Postnatal Growth in Very Low-Birth-Weight Infants.

JPEN J Parenter Enteral Nutr 2019 Feb 12. Epub 2019 Feb 12.

Department of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden.

Background: Evidence showing the beneficial effects of enhanced parenteral nutrition (PN) to very low-birth-weight (VLBW, <1500 g) infants is accumulating. However, PN composition and its impact on growth outcomes are questioned. This study aimed to investigate the associations between administration of a concentrated PN regime and intakes of energy and macronutrients as well as postnatal growth in VLBW infants. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jpen.1522
Publisher Site
http://dx.doi.org/10.1002/jpen.1522DOI Listing
February 2019
20 Reads

PEP uP (Enhanced Protein-Energy Provision via the Enteral Route Feeding Protocol) in Surgical Patients-A Multicenter Pilot Randomized Controlled Trial.

JPEN J Parenter Enteral Nutr 2019 Feb 11. Epub 2019 Feb 11.

Clinical Evaluation Research Unit, Kingston General Hospital, Department of Critical Care, Queen's University, Kingston, Ontario, Canada.

Background: The Enhanced Protein-Energy Provision via the Enteral Route Feeding Protocol (PEP uP) has been shown to be feasible, safe, and effective in delivering significantly more energy/protein, though it has not been well studied in surgical/trauma patients. We hypothesized that PEP uP will effectively increase energy/protein delivery to critically ill surgical/trauma patients.

Methods: This multicenter, prospective, randomized pilot study included adult patients admitted to surgical service who were expected to require mechanical ventilation for >24 hours and intensive care unit (ICU) care for >72 hours. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jpen.1521
Publisher Site
http://dx.doi.org/10.1002/jpen.1521DOI Listing
February 2019
8 Reads

Influence of Methods Used to Establish Sarcopenia Cutoff Values for Skeletal Muscle Measures Using Unenhanced and Contrast-Enhanced Computed Tomography Images.

JPEN J Parenter Enteral Nutr 2019 Feb 11. Epub 2019 Feb 11.

Department of Radiology, Third Xiangya Hospital of Central South University, Changsha, China.

Background: Multiple cutoff values of computed tomography (CT)-based skeletal muscle measures have been proposed, but there is currently no consensus used to identify sarcopenia. We aimed to evaluate the influence of statistical methods used to establish sarcopenia cutoff values and to examine the impact of contrast enhancement on the skeletal muscle measures.

Methods: The skeletal muscle area (SMA) and muscle radiation attenuation (MRA) of 316 healthy individuals were measured on unenhanced CT images at the third lumbar vertebra level, and the skeletal muscle index (SMI) was SMA divided by height squared. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1519DOI Listing
February 2019
3.151 Impact Factor

JPEN Journal Club 43. Stratification.

Authors:
Ronald L Koretz

JPEN J Parenter Enteral Nutr 2019 Feb 7. Epub 2019 Feb 7.

Olive View-UCLA Medical Center, David Geffen-UCLA School of Medicine, Sylmar and Los Angeles, California, USA.

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/jpen.1523
Publisher Site
http://dx.doi.org/10.1002/jpen.1523DOI Listing
February 2019
3 Reads

High Branched-Chain Amino Acid Concentrations Are Found in Preterm Baboons Receiving Intravenous Amino Acid Solutions and Mimic Alterations Found in Preterm Infants.

JPEN J Parenter Enteral Nutr 2019 Feb 7. Epub 2019 Feb 7.

Texas Pregnancy and Life-course Health Research Center, Department of Animal Science, University of Wyoming, Laramie, Wyoming, USA.

Background: Parenteral amino acid (AA) nutrition administration after premature birth is necessary to ensure adequate growth and neurodevelopment. However, optimizing safety and efficacy remains a major challenge. This study investigated the effects of intravenous AA administration on plasma AA profiles in premature baboons and infants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1507DOI Listing
February 2019
1 Read

Cross-sectional Evaluation of Home Enteral Nutrition Practice in the United States in the Context of the New Enteral Connectors.

JPEN J Parenter Enteral Nutr 2019 Feb 7. Epub 2019 Feb 7.

Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, USA.

Purpose: The increased prevalence of home enteral nutrition (HEN), reemergence of blenderized tube feeding (BTF), and conversion of enteral connectors to the ISO 80369-3 standard are creating a significant need to better understand the practices of the HEN population. A cross-sectional survey of current HEN consumers was conducted to evaluate the demographics of HEN consumers, including formulas and feeding tubes being used.

Methods: In order to disseminate the survey to a wide range of HEN consumers, we partnered with private infusion companies (Coram and Pediatric Home Services) along with the Oley and Tube Feeding Awareness Foundations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1510DOI Listing
February 2019

JPEN Journal Club 42. Factorial Design.

Authors:
Ronald L Koretz

JPEN J Parenter Enteral Nutr 2019 Feb 4. Epub 2019 Feb 4.

Olive View-UCLA Medical Center, David Geffen-UCLA School of Medicine, Sylmar and Los Angeles, California, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jpen.1509
Publisher Site
http://dx.doi.org/10.1002/jpen.1509DOI Listing
February 2019
8 Reads

Antecedent Administration of Glutamine Benefits the Homeostasis of CD4 T Cells and Attenuates Lung Injury in Mice With Gut-Derived Polymicrobial Sepsis.

JPEN J Parenter Enteral Nutr 2019 Feb 4. Epub 2019 Feb 4.

Department of Surgery, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

Background: Sepsis is a syndrome with CD4 T-cell dysfunction and dysregulation of T helper (Th) and regulatory T (Treg) cells. Glutamine (Gln) is a nutrient with immunomodulatory properties. This study investigated the effects of dietary Gln pretreatment on Th and Treg cell homeostasis and lung injury in mice with gut-derived polymicrobial sepsis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1505DOI Listing
February 2019

Assessing Patient Preferences for Intestinal Failure Management Using the Time Trade-Off Methodology.

JPEN J Parenter Enteral Nutr 2019 Feb 4. Epub 2019 Feb 4.

Royal Prince Alfred Hospital, Sydney, Australia.

Background: There are limited management options available for people with Type III intestinal failure (IF), with home parenteral nutrition (HPN) being the main treatment option. The aim of this research is to compare patient preferences in managing Type III IF using time trade-off (TTO) methodology and to determine which factors have the greatest impact on health-related quality of life (HRQoL).

Methods: An interviewer-administered telephone survey was conducted on a cross-sectional cohort of 19 HPN participants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1506DOI Listing
February 2019
1 Read

Prevalence of Malnutrition Risk and the Impact of Nutrition Risk on Hospital Outcomes: Results From nutritionDay in the U.S.

JPEN J Parenter Enteral Nutr 2019 Jan 22. Epub 2019 Jan 22.

Division Cardiac, Thoracic, and Vascular Anaesthesia and Intensive Care, Medical University Vienna, Vienna, Austria.

Background: Malnutrition risk estimates vary greatly, and no robust data on the association between food intake and outcomes exist for hospitals in the United States (U.S.). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1499DOI Listing
January 2019
4 Reads

JPEN Journal Club 41. Propensity Scoring.

Authors:
Ronald L Koretz

JPEN J Parenter Enteral Nutr 2019 Mar 15;43(3):442-444. Epub 2019 Jan 15.

Olive View-UCLA Medical Center, David Geffen-UCLA School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1501DOI Listing
March 2019
2 Reads

Pilot Study of the Effect of Plant-Based Enteral Nutrition on the Gut Microbiota in Chronically Ill Tube-Fed Children.

JPEN J Parenter Enteral Nutr 2019 Jan 15. Epub 2019 Jan 15.

Department of Surgery, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.

Background: Dietary intake sharply impacts the structure and function of the gut microbiota, which is important for childhood health. However, little is known about the microbiota of children who cannot eat by mouth. Standard enteral formulas for supplemental nutrition are low in fiber and high in processed sugars and are commonly associated with gastrointestinal side effects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1504DOI Listing
January 2019
1 Read

Novel Long-Acting GLP-2 Analogue, FE 203799 (Apraglutide), Enhances Adaptation and Linear Intestinal Growth in a Neonatal Piglet Model of Short Bowel Syndrome with Total Resection of the Ileum.

JPEN J Parenter Enteral Nutr 2019 Jan 6. Epub 2019 Jan 6.

Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.

Background: Glucagon-like peptide-2 (GLP-2) is an intestinotrophic factor released from L-cells in the ileum, a segment commonly resected or atretic in neonatal short bowel syndrome (SBS). In piglets, ileal resection decreases intestinal adaptation and endogenous GLP-2 production, whereas exogenous replacement promotes adaptation. In this study, we determined the effect of a novel long-acting GLP-2 analogue, FE 203799 (FE; apraglutide), upon intestinal growth, adaptation, and function in neonatal SBS piglets without ileum. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jpen.1500
Publisher Site
http://dx.doi.org/10.1002/jpen.1500DOI Listing
January 2019
25 Reads

Enteral Docosahexaenoic Acid and Retinopathy of Prematurity: A Randomized Clinical Trial.

JPEN J Parenter Enteral Nutr 2019 Jan 6. Epub 2019 Jan 6.

División de Pediatría, Hospital de Gineco-Obstetricia No.3, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Ciudad de México, México.

Background: Retinopathy of prematurity (ROP) is a disorder of the retina of low-birth-weight preterm infants that potentially leads to blindness. Docosahexaenoic acid (DHA), is protective in experimental models, but its administration as part of parenteral nutrition has shown inconsistent results. We test the effect of enteral DHA to prevent ROP and/or severity and to reduce hospital stay. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1497DOI Listing
January 2019
1 Read
3.151 Impact Factor

Effect of Early Parenteral Nutrition Discontinuation on Time to Regain Birth Weight in Very Low Birth Weight Infants: A Randomized Controlled Trial.

JPEN J Parenter Enteral Nutr 2019 Jan 6. Epub 2019 Jan 6.

Coombe Women and Infants University Hospital, Dublin, Ireland.

Background: Peripherally inserted central catheters (PICCs) are used to administer parenteral nutrition (PN) in very low birth weight infants (VLBW; <1500 g). Clinicians try to optimize early nutrition but also minimize the risks associated with intravascular devices. The objective of this study was to examine the early nutrition impact of discontinuing PN at different enteral feed volumes in VLBW infants. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jpen.1502
Publisher Site
http://dx.doi.org/10.1002/jpen.1502DOI Listing
January 2019
10 Reads

Milk Fat Globule Membrane Ameliorates Necrotizing Enterocolitis in Neonatal Rats and Suppresses Lipopolysaccharide-Induced Inflammatory Response in IEC-6 Enterocytes.

JPEN J Parenter Enteral Nutr 2019 Jan 6. Epub 2019 Jan 6.

Shanghai Institute for Pediatric Research, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Background: Evidence has provided support for the beneficial effects of milk fat globule membrane (MFGM) on inflammation in the intestinal tract. The objective of this study was to investigate the effects of MFGM on a rat model of necrotizing enterocolitis (NEC) and its potential mechanism of action.

Methods: Sixty-two newborn Sprague Dawley rats were randomly divided into 4 experimental groups: Breast-fed normal, formula fed (FF), FF + 6 g/L MFGM, and FF + 12 g/L MFGM. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1496DOI Listing
January 2019
1 Read

Priorities for Nutrition Research in Pediatric Critical Care.

JPEN J Parenter Enteral Nutr 2018 Dec 26. Epub 2018 Dec 26.

Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Background: Widespread variation exists in pediatric critical care nutrition practices, largely because of the scarcity of evidence to guide best practice recommendations.

Objective: The objective of this paper was to develop a list of topics to be prioritized for nutrition research in pediatric critical care in the next 10 years.

Methods: A modified 3-round Delphi process was undertaken by a newly established multidisciplinary group comprising 11 international researchers in the field of pediatric critical care nutrition. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jpen.1498
Publisher Site
http://dx.doi.org/10.1002/jpen.1498DOI Listing
December 2018
21 Reads

Successful Management of Ketogenic Parenteral Nutrition: A Pediatric Case Study.

JPEN J Parenter Enteral Nutr 2018 Dec 20. Epub 2018 Dec 20.

Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1490DOI Listing
December 2018
1 Read

Bolus vs Continuous Nasogastric Feeds in Mechanically Ventilated Pediatric Patients: A Pilot Study.

JPEN J Parenter Enteral Nutr 2018 Dec 20. Epub 2018 Dec 20.

Pediatric Intensive Care Unit, Akron Children's Hospital, Akron, Ohio, USA.

Background: Malnutrition increases the risk of mortality and morbidity in the pediatric intensive care unit (PICU). Barriers to adequate delivery of enteral nutrition (EN) include hemodynamic instability, feeding interruptions and intolerance, and lack of standardized feeding protocols. The most recent guidelines on nutrition support for the critically ill child describe a paucity of evidence around the best method to deliver EN. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1495DOI Listing
December 2018
1 Read

Specialized High-Protein Oral Nutrition Supplement Improves Home Nutrient Intake of Malnourished Older Adults Without Decreasing Usual Food Intake.

JPEN J Parenter Enteral Nutr 2018 Nov 22. Epub 2018 Nov 22.

Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.

Background: Reduced nutrient intake is common in patients after hospitalization, contributing to increased risk for readmission and mortality. Oral nutrition supplements can improve nutrition status and clinical outcomes, but intake of food is prioritized by clinicians. This study examines the impact of a high-protein oral nutrition supplement (S-ONS) on nutrient intake post discharge. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1467DOI Listing
November 2018
4 Reads

Factors Associated With Use of Nonoral Nutrition and Hydration Support in Adult Patients With Postural Tachycardia Syndrome.

JPEN J Parenter Enteral Nutr 2018 Dec 18. Epub 2018 Dec 18.

Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, Arizona, USA.

Background: Patients with postural tachycardia syndrome (POTS) often have gastrointestinal (GI) symptoms. Occasionally, these symptoms can be so severe that nonoral nutrition/hydration support (NONHS), including intravenous fluids (IVFs), enteral nutrition (EN), and parenteral nutrition (PN), becomes necessary.

Methods: This is a retrospective cohort study of adult patients diagnosed with POTS at the Mayo Clinic Arizona from January 2010 to January 2017 with a minimum of 6 months of follow up. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jpen.1493
Publisher Site
http://dx.doi.org/10.1002/jpen.1493DOI Listing
December 2018
11 Reads

Sarcopenia Index Is a Simple Objective Screening Tool for Malnutrition in the Critically Ill.

JPEN J Parenter Enteral Nutr 2018 Dec 18. Epub 2018 Dec 18.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.

Background: Reliable and valid tools to screen for malnutrition in the intensive care unit (ICU) remain elusive. The sarcopenia index (SI) [(serum creatinine/serum cystatin C) × 100], could be an inexpensive, objective tool to predict malnutrition. We evaluated the SI as a screening tool for malnutrition in the ICU and compared it with the modified-NUTRIC score. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1492DOI Listing
December 2018
1 Read

Effect of Psyllium Fiber Supplementation on Diarrhea Incidence in Enteral Tube-Fed Patients: A Prospective, Randomized, and Controlled Trial.

JPEN J Parenter Enteral Nutr 2018 Dec 18. Epub 2018 Dec 18.

Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.

Background: Diarrhea in enteral tube-fed patients is not uncommon and can lead to unfavorable outcomes. Fiber in enteral nutrition (EN) formula might play a role in postfeeding diarrhea. Theoretically, soluble fiber is beneficial for both prevention and treatment of postfeeding diarrhea, but different types of soluble fiber may not provide the same effect. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jpen.1489DOI Listing
December 2018