1,499 results match your criteria JOP: Journal of the Pancreas[Journal]


Comparable Responses in Male and Female Mice to Cerulein-Induced Chronic Pancreatic Injury and Recovery.

JOP 2018 Sep 28;19(5):236-243. Epub 2018 Sep 28.

Department of Surgery, UTHealth, 6431 Fannin Street, Houston, TX 77030, USA.

Objective: The cerulein-induced mouse pancreatitis model is a well-established, commonly used representation of human chronic pancreatitis pathology. Although studies report sex-dependent differences in human chronic pancreatitis, there are no studies in this model directly comparing sex response to pancreatic injury and recovery. Therefore, we designed a study to investigate whether sex- dependent differences in chronic pancreatitis injury and recovery exist in the cerulein-induced pancreatitis model. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327960PMC
September 2018
1 Read

An Appraisal of Current Guidelines for Managing Malignancy in Pancreatic Intraductal Papillary Mucinous Neoplasm.

JOP 2018 Jul 30;19(4):178-182. Epub 2018 Jul 30.

Division of Gastroenterology and Hepatology, Department of Internal Medicine.

Pancreatic intraductal papillary mucinous neoplasm was originally regarded as a benign mucinous cystic tumor but certainly has a marked malignant potential. With the array of high-resolution imaging modalities that are now available, more frequent incidental asymptomatic intraductal papillary mucinous neoplasm patients can be diagnosed. Until now, our clinicians have been managing intraductal papillary mucinous neoplasm patients by referring to the international consensus guidelines which have been revised twice or American Gastroenterological Association guidelines. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327957PMC

Pancrelipase-Induced Hypersensitivity Reaction: Case Report and Review of Literature.

JOP 2018 Sep;19(5):273-275

Tufts University School of Medicine, Boston, MA, 02111.

Introduction: Drug-induced exanthems are commonly associated with NSAIDs, antibiotics, and anti-epileptics. Pancrelipase is frequently used for conditions resulting in pancreatic exocrine insufficiency. Published case reports of pancrelipase hypersensitivity focus on the respiratory manifestations. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217990PMC
September 2018
1 Read

Cutaneous Metastasis of Gastroenteropancreatic Neuroendocrine Tumors (GEP-Nets).

JOP 2018 Sep 18;19(5). Epub 2018 Sep 18.

The Department of Medicine, Tufts Medical Center, Boston MA, USA.

Background: Gastroenteropancreatic neuroendocrine tumors are neoplasms commonly found within the gastrointestinal tract that originate from endocrine cells. These are slow progressive tumors and often metastasize to other elements of the gastrointestinal tract including the liver. Consequently, these tumors release hormones including serotonin and/or histamine that are responsible for the symptoms including intermittent flushing and diarrhea. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217987PMC
September 2018
9 Reads

Screening of Pancreatic Cancer.

JOP 2018 May;19(3):109-112

Tufts University School of Medicine, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063088PMC

Perioperative and Survival Outcomes Following Neoadjuvant FOLFIRINOX versus Gemcitabine Abraxane in Patients with Pancreatic Adenocarcinoma.

JOP 2018 Mar 30;19(2):75-85. Epub 2018 Mar 30.

Department of Surgery, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.

Context: Neoadjuvant chemotherapy is increasingly used in borderline resectable and locally advanced pancreatic cancer to facilitate surgical resection.

Objective: To compare progression free survival and overall survival in patients receiving neoadjuvant FOLFIRINOX with those receiving gemcitabine/abraxane.

Design: Retrospective cohort study. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018015PMC
March 2018
8 Reads

Preventing Post-ERCP Pancreatitis: The Role of Prophylactic Pancreatic Duct Stenting in the Rectal NSAID Era.

JOP 2017 Jul 31;18(4):316-319. Epub 2017 Jul 31.

Pancreaticobiliary Medicine Unit, University College London Hospitals NHS Foundation Trust, London, United Kingdom.

Background: Rectal non-steroidal anti-inflammatory drug at endoscopic retrograde cholangiopancreatography is now the standard of care to reduce the risk of post-ERCP pancreatitis. Pancreatic duct stenting also reduces the risk of post- ERCP pancreatitis in high-risk patients, but failed pancreatic duct stenting carries an increased PEP rate (up to 35%).

Study Aim: To assess the impact on post-ERCP pancreatitis of successful and unsuccessful pancreatic duct stent placement in the setting of universal rectal non-steroidal anti-inflammatory drug use. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933872PMC
July 2017
4 Reads

Management of Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) in 2017.

JOP 2017 Nov 30;18(6):444-447. Epub 2017 Nov 30.

Tufts University School of Medicine, Tufts Cancer Center, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870128PMC
November 2017
1 Read

Efficacy of Endotherapy in the Treatment of Pain Associated With Chronic Pancreatitis: A Systematic Review and Meta-Analysis.

JOP 2017 Mar 30;18(2):125-132. Epub 2017 Mar 30.

Columbia University Medical Center, USA.

Background: Endotherapy is a treatment modality that can be used to manage the pain associated with chronic pancreatitis. The aim of this systematic review and meta-analysis is to evaluate the efficacy of endotherapy in the management of pain associated with chronic pancreatitis.

Methods: A search of Medline, Pubmed, and Embase databases between 1988 to December 2014 was conducted to evaluate the use of endotherapy for pain relief in patients with chronic pancreatitis. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619873PMC
March 2017
7 Reads

The Role of Real Time Endoscopic Ultrasound Guided Elastography for Targeting EUS-FNA of Suspicious Pancreatic Masses: A Review of the Literature and A Single Center Experience.

JOP 2016 09;17(5):516-524

Columbia University College of Physicians and Surgeons, New York, USA.

Background: Endoscopic ultrasound guided elastography is an imaging modality that can be used to evaluate tissue stiffness and to assess solid pancreatic lesions. It can also assist in optimizing the diagnostic yield of endoscopic ultrasound guided fine needle aspiration biopsies.

Aims: To review the literature on solid pancreatic lesions, the use of EUS guided fine needle aspiration and endoscopic ultrasound guided elastography and to present a single center experience using elastography to direct fine needle aspiration biopsies of solid pancreatic lesions. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595420PMC
September 2016
5 Reads

Confocal Endomicroscopy Characteristics of Different Intraductal Papillary Mucinous Neoplasm Subtypes.

JOP 2017 May;18(Suppl 2):198-202

Department of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH.

Intraductal papillary mucinous neoplasms are classified into gastric, intestinal, pancreatobiliary, and oncocytic subtypes where morphology portends disease prognosis. The study aim was to demonstrate EUS-guided needle-based confocal laser endomicroscopy imaging features of intraductal papillary mucinous neoplasm subtypes. Four subjects, each with a specific intraductal papillary mucinous neoplasm subtype were enrolled. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558896PMC
May 2017
33 Reads

The Burden of Systemic Adiposity on Pancreatic Disease: Acute Pancreatitis, Non-Alcoholic Fatty Pancreas Disease, and Pancreatic Cancer.

JOP 2017 ;18(5):365-368

Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

Obesity is a global epidemic as recognized by the World Health Organization. Obesity and its related comorbid conditions were recognized to have an important role in a multitude of acute, chronic, and critical illnesses including acute pancreatitis, nonalcoholic fatty pancreas disease, and pancreatic cancer. This review summarizes the impact of adiposity on a spectrum of pancreatic diseases. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826578PMC
January 2017
2 Reads

Diabetes Type 2 and Pancreatic Cancer: A History Unfolding.

JOP 2016 Mar;17(2):144-148

Department of Hematology and Oncology, Tufts Medical Center, Boston, MA, USA.

Pancreatic Cancer is the fourth cause of cancer-related deaths in the United States. Up to 80% of pancreatic cancer patients present with either new-onset type 2 diabetes or impaired glucose tolerance at the time of diagnosis. Recent literature suggests that diabetes mellitus type 2 is a risk factor, a manifestation and a prognostic factor for pancreatic cancer. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860818PMC
March 2016
1 Read

Is Total Pancreatectomy with Islet Autotransplantation A Reasonable Choice for Pediatric Pancreatitis?

JOP 2015 8;16(4):335-41. Epub 2015 Jul 8.

University of Iowa Children's Hospital, Iowa City, IA, USA.

Chronic pancreatitis is an emerging and poorly understood disease in childhood. Total pancreatectomy with islet cell autotransplantation is being proposed as a treatment for chronic pancreatitis and recent studies report a more favorable outcome in children compared to adults. Herein, we review the therapeutic alternatives for pediatric chronic pancreatitis, focusing primarily on TP/IAT. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624457PMC
November 2015
3 Reads

IgG4-Related Disease.

JOP 2015 Mar 20;16(2):217. Epub 2015 Mar 20.

Kyoto University. Kyoto Japan.

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http://dx.doi.org/10.6092/1590-8577/2945DOI Listing
March 2015
2 Reads

Reply to "comments on the article: management of suspected acute inflammatory pancreatopathies in a "real-world" setting - a single-centre observational study".

JOP 2015 Mar 20;16(2):216. Epub 2015 Mar 20.

Department of Translational Medicine, School of Medicine and Psychology, University of Rome "Sapienza". Rome, Italy.

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http://dx.doi.org/10.6092/1590-8577/2964DOI Listing
March 2015
3 Reads

Comments on "risk factors associated with recurrence in patients with solid pseudopapillary tumors of the pancreas".

Authors:
Xing Wang Xubao Liu

JOP 2015 Mar 20;16(2):213. Epub 2015 Mar 20.

Department of Hepatopancreatobiliary Surgery, West China Hospital, Sichuan University. Chengdu, China.

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http://www.serena.unina.it/index.php/jop/article/view/2944
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http://dx.doi.org/10.6092/1590-8577/2944DOI Listing
March 2015
4 Reads

Undifferentiated (spindle cell) pancreatic carcinoma: a case report with osteochondroid differentiation.

JOP 2015 Mar 20;16(2):209-12. Epub 2015 Mar 20.

Department of Hepatopancreatobiliary Surgery, West China Hospital, Sichuan University. Chengdu, China.

Context: Undifferentiated (spindle cell) carcinomas of the pancreas are rare anaplastic variants of pancreatic ductal adenocarcinoma with a frequency of 2% of pancreatic exocrine tumors. Their clinicopathological features are limited and obtained by few previously case reports. We report a case of undifferentiated pancreatic carcinoma with a rare focal osteochondroid differentiation. Read More

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http://dx.doi.org/10.6092/1590-8577/2960DOI Listing
March 2015
9 Reads

Seventy-two Cycles of FOLFIRINOX: Long Term Treatment in a Patient with Metastatic Adenocarcinoma of the Pancreatic Tail.

JOP 2015 Mar 20;16(2):205-8. Epub 2015 Mar 20.

Department of Gastroenterology, Hepatology and Gastrointestinal Oncology, Bogenhausen Academic, Teaching Hospital, Munich Municipal Hospital Trust. Munich, Germany.

Context: Pancreatic adenocarcinoma is one of the most lethal malignancies worldwide. In patients with unresectable tumor there are several strategies of palliative chemotherapy, either gemcitabine based regimens or FOLFIRINOX, which is supposed to be most efficient but also most toxic. Hence, management of toxicity is crucial to perform a therapy consisting of FOLFIRINOX. Read More

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http://www.serena.unina.it/index.php/jop/article/view/2962
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http://dx.doi.org/10.6092/1590-8577/2962DOI Listing
March 2015
18 Reads

Acute pancreatitis secondary to diabetic ketoacidosis induced hypertriglyceridemia in a young adult with undiagnosed type 2 diabetes.

JOP 2015 Mar 20;16(2):201-4. Epub 2015 Mar 20.

University of New South Wales. Kensington, NSW, Australia.

Context: The triad of acute pancreatitis, hypertriglyceridemia and diabetes is a rare occurrence.

Case Report: A previously well 19-year-old male presented to the emergency department with 24-hour history of epigastric pain, associated with polyuria and nausea. Biochemical markers showed the presence of hyperglycemia (blood sugar level 15 mmol/L) and ketonemia (5. Read More

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http://www.serena.unina.it/index.php/jop/article/view/2961
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http://dx.doi.org/10.6092/1590-8577/2961DOI Listing
March 2015
5 Reads

Reconstructive strategy after pancreaticoduodenectomy in partially gastrectomized patients.

JOP 2015 Mar 20;16(2):198-200. Epub 2015 Mar 20.

Department of Surgery and Translational Medicine, University of Florence. Florence, Italy.

Context: Pancreaticoduodenectomy in partially-gastrectomized patients presents some peculiarities of the reconstructive phase. Above all, in B II and Roux-en-Y partial gastrectomies, a gastric re-resection with a redo gastrojejunal anastomosis should be avoided because it is often needlessly time-consuming and risky. In our series of 7 consecutive patients, either one of two reconstruction methods was used, depending upon the length of the pre-existing afferent loop. Read More

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http://dx.doi.org/10.6092/1590-8577/2956DOI Listing
March 2015
20 Reads

Atypical presentation of disseminated intravascular coagulation with synchronous peripheral venous thromboembolism and arterial gangrene in a pancreatic cancer patient: a case report.

JOP 2015 Mar 20;16(2):195-7. Epub 2015 Mar 20.

Division of Oncology, Department of Internal Medicine, University of Gaziantep. Gaziantep, Turkey.

Context: Cancer is a prothrombotic state and anticancer therapies are often complicated by vascular events. The risk of developing thromboembolic events is substantially increased in patients with pancreatic cancer. One possible presentation of vascular events in pancreatic cancer is disseminated intravascular coagulation (DIC). Read More

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http://dx.doi.org/10.6092/1590-8577/2943DOI Listing
March 2015
63 Reads

Acute pancreatitis as initial presentation of cocaine-induced vasculitis: a case report.

JOP 2015 Mar 20;16(2):192-4. Epub 2015 Mar 20.

Department of Internal Medicine, Unity Health System. Rochester, NY, USA.

Context: Levamisole-contaminated cocaine is an increasingly reported cause of vasculitis and immunologic abnormalities in cocaine abusers. The systemic effects of vasculitis are commonly seen in the dermatologic, hematologic and renal systems but rarely the gastrointestinal system.

Case Report: We present an atypical case of cocaine-induced vasculitis presenting initially as an acute pancreatitis and then rapidly progressing to involve multi-organ systems over the next couple of weeks. Read More

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http://dx.doi.org/10.6092/1590-8577/2942DOI Listing
March 2015
16 Reads

A triad of complete dorsal pancreatic agenesis, pancake kidney and bicornuate uterus. An association or an incidental finding: first case in literature.

JOP 2015 Mar 20;16(2):189-91. Epub 2015 Mar 20.

Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research. Chandigarh, India.

Context: Agenesis of the dorsal pancreas is a rare congenital anomaly which can be detected either incidentally during imaging or encountered during investigation for pancreas related pathologies such as pancreatitis or diabetes mellitus. Few associations of this condition with heterotaxy syndrome, pancreatic tumors and congenital heart disease have been described.

Case Report: We report a novel association of genitourinary anomalies in a case of complete dorsal pancreatic agenesis not previously described in the literature. Read More

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http://dx.doi.org/10.6092/1590-8577/2949DOI Listing
March 2015
8 Reads
2 Citations

Small bowel perforation caused by pancreaticojejunal anastomotic stent migration after pancreaticoduodenectomy for periampullary carcinoma.

JOP 2015 Mar 20;16(2):185-8. Epub 2015 Mar 20.

Department of General Surgery, AO Vimercate Hospital of Desio. Vimercate, MB, Italy.

Context: Pancreaticoduodenectomy is the gold standard for patients with resectable periampullary carcinoma. The protection of the anastomosis by positioning of an intraluminal stent is a technique used to lower the frequency of anastomotic fistulas. However the use of anastomotic stents is still debated and stent related complications are reported. Read More

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http://pancreas.imedpub.com/small-bowel-perforation-caused-b
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http://dx.doi.org/10.6092/1590-8577/2957DOI Listing
March 2015
9 Reads

Lazaroid U-74389G Administration in Pancreatic Ischemia-Reperfusion Injury: A Swine Model Encompassing Ischemic Preconditioning.

JOP 2015 Mar 20;16(2):176-84. Epub 2015 Mar 20.

Department of Propaedeutic Surgery, Hippokratio Hospital. Athens, Greece.

Context: The potential of lazaroid U-74389G in attenuating injury after ischemia and reperfusion has been reported in various organs.

Objective: The present study focuses specifically on the pancreas and aims to examine any effects of U-74389G in a swine model of pancreatic ischemia and reperfusion, encompassing ischemic preconditioning.

Methods: Twelve pigs, weighing 28-35 kg, were randomized into two experimental groups. Read More

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http://pancreas.imedpub.com/lazaroid-u74389g-administration-
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http://dx.doi.org/10.6092/1590-8577/2952DOI Listing
March 2015
19 Reads

Does etiology of acute pancreatitis matter? A review of 391 consecutive episodes.

JOP 2015 Mar 20;16(2):171-5. Epub 2015 Mar 20.

Gastroenterology, Medical Department I, University Hospital of Schleswig-Holstein, Campus Lübeck. Lübeck, Germany.

Context: Acute pancreatitis can be triggered by a variety of factors ranging from short lasting to sustained disruptions. It is plausible that the characteristics and course of disease differ among etiologies. Data distinguishing characteristics of patients with pancreatitis of biliary, alcoholic, idiopathic or other origin are scarce and conflicting. Read More

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http://dx.doi.org/10.6092/1590-8577/2959DOI Listing
March 2015
3 Reads

Effect of Unripe Plantain (Musa paradisiaca) and Ginger (Zingiber officinale) on Renal Dysfunction in Streptozotocin-Induced Diabetic Rats.

JOP 2015 Mar 20;16(2):167-70. Epub 2015 Mar 20.

Department of Food Science and Technology, Abia State Polytechnic. Aba, Nigeria.

Context: Although unripe plantain (Musa paradisiaca) and ginger (Zingiber officinale) are used as single plants to manage diabetes mellitus in Nigeria, the possibility of combining them in a typical diabetic diet and the glycemic response elicited as a result of such combination has not been investigated.

Objective: To determine the effect of unripe plantain and ginger on serum total proteins, albumin, creatinine and urea levels of streptozotocin induced diabetic rats.

Methods: Twenty four male albino rats were used and were divided into 4 groups of 6 rats each. Read More

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http://dx.doi.org/10.6092/1590-8577/2954DOI Listing
March 2015
12 Reads

Long-term outcomes after acute necrotizing pancreatitis: what happens to the pancreas and to the patient?

JOP 2015 Mar 20;16(2):159-66. Epub 2015 Mar 20.

Department of Gastroenterology, Santa Casa School of Medicine. São Paulo, Brazil.

Context: Late consequences of acute pancreatitis have received little attention. It is controversial whether the pancreas fully recovers after an episode of acute pancreatitis, especially in the presence of necrosis. Therefore, the presence of late pancreatic dysfunction following acute necrotizing pancreatitis is uncertain and there are controversies about how it may affect long-term quality of life. Read More

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http://dx.doi.org/10.6092/1590-8577/2958DOI Listing
March 2015
15 Reads

Ultrasound-assisted focused open necrosectomy in the treatment of necrotizing pancreatitis.

JOP 2015 Mar 20;16(2):150-8. Epub 2015 Mar 20.

Department of General and Emergency Surgery, Riga East Clinical University Hospital. Riga, Latvia.

Context: The surgical treatment of necrotizing pancreatitis includes percutaneous drainage of acute necrotic collections and sequestrectomy in the late phase of the disease.

Objective: The aim of the study was to compare the conventional open necrosectomy (CON) approach with the alternative focused open necrosectomy (FON) approach in patients with infected necrosis and progression of sepsis.

Methods: Patients with acute necrotizing pancreatitis were included in the study prospectively from January 2004 to July 2014. Read More

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http://dx.doi.org/10.6092/1590-8577/2953DOI Listing
March 2015
25 Reads

The role of molecular analysis in the diagnosis and surveillance of pancreatic cystic neoplasms.

JOP 2015 Mar 20;16(2):143-9. Epub 2015 Mar 20.

Department of Surgery, Columbia University. New York, NY, USA.

Context: Molecular analysis of pancreatic cyst fluid obtained by EUS-FNA may increase diagnostic accuracy. We evaluated the utility of cyst-fluid molecular analysis, including mutational analysis of K-ras, loss of heterozygosity (LOH) at tumor suppressor loci, and DNA content in the diagnoses and surveillance of pancreatic cysts.

Methods: We retrospectively reviewed the Columbia University Pancreas Center database for all patients who underwent EUS/FNA for the evaluation of pancreatic cystic lesions followed by surgical resection or surveillance between 2006-2011. Read More

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http://pancreas.imedpub.com/the-role-of-molecular-analysis-i
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http://dx.doi.org/10.6092/1590-8577/2941DOI Listing
March 2015
6 Reads

Crohn's disease and acute pancreatitis. A review of literature.

JOP 2015 Mar 20;16(2):136-42. Epub 2015 Mar 20.

Department of Medicine, Monmouth Medical Center. Long Branch, NJ, USA.

Crohn's disease, a transmural inflammatory bowel disease, has many well-known extra-intestinal manifestations and complications. Although acute pancreatitis has a higher incidence in patients with Crohn's disease as compared to the general population, acute pancreatitis is still relatively uncommon in patients with Crohn's disease. Patients with Crohn's disease are at an approximately fourfold higher risk than the general population to develop acute pancreatitis. Read More

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http://dx.doi.org/10.6092/1590-8577/2951DOI Listing
March 2015
3 Reads

Necrotizing pancreatitis: a review of multidisciplinary management.

JOP 2015 Mar 20;16(2):125-35. Epub 2015 Mar 20.

Department of Surgery, Saint Agnes Hospital. Baltimore, MD, USA.

The objective of this review is to summarize the current state of the art of the management of necrotizing pancreatitis, and to clarify some confusing points regarding the terminology and diagnosis of necrotizing pancreatitis, as these points are essential for management decisions and communication between providers and within the literature. Acute pancreatitis varies widely in its clinical presentation. Despite the publication of the Atlanta guidelines, misuse of pancreatitis terminology continues in the literature and in clinical practice, especially regarding the local complications associated with severe acute pancreatitis. Read More

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http://dx.doi.org/10.6092/1590-8577/2947DOI Listing
March 2015
5 Reads

Postoperative Pancreatic Fistula: A Surgeon's Nightmare! An Insight with a Detailed Literature Review.

JOP 2015 Mar 20;16(2):115-24. Epub 2015 Mar 20.

Kasturba Medical College, Manipal University. Manipal, India.

Context: Postoperative fistula formation is an important complication following pancreatic resections.

Objective: A large volume of literature without uniform conclusions is available regarding various controversies about postoperative pancreatic fistulae. The term postoperative pancreatic fistula includes fistula resulting from any surgery involving pancreas, most commonly pancreaticoduodenectomy and distal pancreatectomy. Read More

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http://dx.doi.org/10.6092/1590-8577/2937DOI Listing
March 2015
2 Reads

Neoadjuvant therapy in pancreatic cancer: review article.

JOP 2015 Mar 20;16(2):110-4. Epub 2015 Mar 20.

University Clinic. Luebeck, Germany.

Context: Pancreatic cancer is still associated with a high mortality and morbidity for affected patients. To this date the role of neoadjuvant therapy in the standard treatment of pancreatic cancer remains elusive. The aim of our study was to review the latest results and current approaches in neoadjuvant therapy of pancreatic cancer. Read More

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http://dx.doi.org/10.6092/1590-8577/2940DOI Listing
March 2015
5 Reads

Pancreatitis developing in the context of acute hepatitis: a literature review.

JOP 2015 Mar 20;16(2):104-9. Epub 2015 Mar 20.

Baqiyatallah Research Center for Gastroenterology and Liver Disease, Baqiyatallah University of Medical Sciences. Tehran, Iran.

Despite strong evidence suggestive of associations between hepatic diseases and pancreas injury, a potential relationship between acute hepatitis and acute pancreatitis has not been a matter of review; which we focused on in the current paper. Some of the main findings of this review article are: fulminant hepatitis failure represents the highest incident rate of hepatitis-related acute pancreatitis; so a screening program might be indicative in these patients. Specific characteristics of HAV-related pancreatitis are that it is a benign condition with no reported mortality; and a male preponderance in the incidence, with females developing in older ages and having shown the signs of both conditions simultaneously. Read More

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http://dx.doi.org/10.6092/1590-8577/2939DOI Listing
March 2015
3 Reads

Advancements in the Management of Pancreatic Cancer: 2015 ASCO Gastrointestinal Cancers Symposium (San Francisco, CA, USA. January 15-17, 2015).

JOP 2015 Mar 20;16(2):99-103. Epub 2015 Mar 20.

Section of GI Cancers and Experimental Therapeutics, Tufts University School of Medicine. Boston, MA, USA.

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http://dx.doi.org/10.6092/1590-8577/2955DOI Listing
March 2015
3 Reads
2 Citations

A critique on the article describing pancreatic mucinous cystic neoplasm size using CT volumetry, spherical and ellipsoid formulas: validation study.

JOP 2015 Jan 31;16(1):97-8. Epub 2015 Jan 31.

Department of Radiology, Seth GS Medical College and KEM Hospital. Mumbai, Maharashtra, India.

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http://dx.doi.org/10.6092/1590-8577/2916DOI Listing
January 2015
3 Reads

Pancreaticopleural fistula as a presentation of a pancreatic neoplasm. A report of a case and review of the literature.

JOP 2015 Jan 31;16(1):95-6. Epub 2015 Jan 31.

Department of Radiology, The National Surgical Centre for Pancreatic Cancer, St Vincent's University Hospital. Dublin, Ireland.

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http://dx.doi.org/10.6092/1590-8577/2895DOI Listing
January 2015
3 Reads

Pancreaticopleural fistula: a review.

JOP 2015 Jan 31;16(1):90-4. Epub 2015 Jan 31.

Department of Radiology, Seth GS Medical College and KEM Hospital. Mumbai, Maharashtra, India.

Pancreaticopleural fistula is a rare complication of chronic pancreatitis consequent to posterior disruption of the pancreatic duct. The fistulous track ascends into the pleural cavity and gives rise to large volumes of pleural fluid. Pancreaticopleural fistula thus poses a diagnostic problem since the source of pleural fluid is extrathoracic. Read More

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http://dx.doi.org/10.6092/1590-8577/2915DOI Listing
January 2015
4 Reads

Arterial pseudoaneurysms following hepato-pancreato-biliary surgery: a single center experience.

JOP 2015 Jan 31;16(1):85-9. Epub 2015 Jan 31.

Department of General Surgery, Madrid Norte Sanchinarro San Pablo University Hospital. Madrid, Spain.

Context: Arterial pseudoaneurysm is an uncommon lethal complication following hepato-pancreato-biliary surgery.

Objective: Aim of this study is to present and discuss the experience of a high volume oncological center.

Methods: Since 2007 all major surgeries performed at Sanchinarro Oncological Center have been included in a prospective database looking for postoperative arterial pseudonaurysm. Read More

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http://pancreas.imedpub.com/arterial-pseudoaneurysms-followi
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http://dx.doi.org/10.6092/1590-8577/2907DOI Listing
January 2015
5 Reads

Somatostatinoma of the minor papilla treated by local excision in a patient with neurofibromatosis type 1.

JOP 2015 Jan 31;16(1):81-4. Epub 2015 Jan 31.

Department of Surgery, University of Melbourne, Austin Health. Heidelberg, Melbourne, Victoria, Australia.

Context: Somatostatinoma arising from the minor papilla in a patient with neurofibromatosis type 1 (NF1) is a known but very rare condition, which may cause non-specific symptoms and can present because of its mass effect.

Case Report: A fifty-year-old female presenting with ongoing non-specific abdominal pain for a few months duration was found to have a mass involving the minor papilla. She had a history of NF1 but was otherwise well. Read More

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http://pancreas.imedpub.com/somatostatinoma-of-the-minor-pap
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http://dx.doi.org/10.6092/1590-8577/2906DOI Listing
January 2015
8 Reads

Wandering spleen with torsion causing pancreatic volvulus and associated intrathoracic gastric volvulus. An unusual triad and cause of acute abdominal pain.

JOP 2015 Jan 31;16(1):78-80. Epub 2015 Jan 31.

Department of Radiology, Seth GS Medical College and KEM Hospital. Mumbai, Maharashtra, India.

Context: Wandering spleen is a rare medical entity in which the spleen is orphaned of its usual peritoneal attachments and thus assumes an ever wandering and hypermobile state. This laxity of attachments may even cause torsion of the splenic pedicle. Both gastric volvulus and wandering spleen share a common embryology owing to maldevelopment of the dorsal mesentery. Read More

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http://pancreas.imedpub.com/wandering-spleen-with-torsion-ca
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http://dx.doi.org/10.6092/1590-8577/2905DOI Listing
January 2015
8 Reads

Surgical intervention for mediastinal pancreatic pseudocysts. A case series and review of the literature.

JOP 2015 Jan 31;16(1):74-7. Epub 2015 Jan 31.

Department of Hepatopancreaticobiliary Surgery, Addenbrooke's Hospital. Cambridge, United Kingdom.

Context: Development of mediastinal pancreatic pseudocysts is a rare complication of pancreatitis. There is currently no consensus on the optimal management of this condition, options for which include conservative management with somatostatin analogues, endoscopic drainage procedures and surgery.

Case Report: Here we present two patients with mediastinal pancreatic pseudocysts which were initially managed endoscopically. Read More

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http://www.serena.unina.it/index.php/jop/article/view/2904
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http://dx.doi.org/10.6092/1590-8577/2904DOI Listing
January 2015
8 Reads

Early-phase thin-slice CT in the diagnosis of small insulinomas.

JOP 2015 Jan 31;16(1):70-3. Epub 2015 Jan 31.

Department of Surgery, Jichi Medical University. Tochigi, Japan.

Context: Insulinomas, which are generally smaller than 2 cm, may be difficult to detect by routine imaging modalities including abdominal ultrasonography, computed tomography, and magnetic resonance imaging. Although preoperative detection of insulinomas is essential for operative planning, it is often challenging due to their small size. While arterial stimulation and venous sampling has been used in patients with insulinomas it has been largely supplanted by early-phase thin-slice computed tomography. Read More

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http://dx.doi.org/10.6092/1590-8577/2901DOI Listing
January 2015
19 Reads

Multimodality treatment by FOLFOX plus HIFU in a case of advanced pancreatic carcinoma. A case report.

JOP 2015 Jan 31;16(1):66-9. Epub 2015 Jan 31.

Medical University. Pleven, Bulgaria.

Context: Pancreatic cancer is one of the most aggressive malignant diseases in which the survival rate has not improved in the past 40 years.

Case Report: A fifty-one-year-old male patient with inoperable metastatic pancreatic cancer and low response to chemotherapy with gemcitabine as single therapy underwent palliative high intensity focused ultrasound (HIFU) ablation. Continuing chemotherapy with folinic acid, oxaliplatin and 5-fluorouracil (FOLFOX) was made. Read More

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http://dx.doi.org/10.6092/1590-8577/2900DOI Listing
January 2015
3 Reads

Intraductal oncocytic papillary neoplasm of the pancreas: a case of a second neoplasm in a pancreas cancer survivor.

JOP 2015 Jan 31;16(1):63-5. Epub 2015 Jan 31.

Division of Gastroenterology, Allegheny Health Network, Allegheny General Hospital. Pittsburgh, PA, USA.

Context: Cystic neoplasms, which are less common forms of exocrine pancreatic neoplasms, consist of mainly intraductal papillary mucinous neoplasms (IPMN) and mucinous cystic neoplasms. Mucinous cystic neoplasms, unlike IPMN, are not associated with ductal growth, are usually multilocular in nature, and have ovarian type stroma. Mucinous cystadenocarcinoma is a type of mucinous cystic neoplasm more commonly found in women. Read More

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http://dx.doi.org/10.6092/1590-8577/2899DOI Listing
January 2015
4 Reads

Altered bone metabolism and bone density in patients with chronic pancreatitis and pancreatic exocrine insufficiency.

JOP 2015 Jan 31;16(1):58-62. Epub 2015 Jan 31.

Gastrocentrum, Karolinska Institutet and University Hospital. Stockholm, Sweden. Department of Medicine II, Medical Faculty Mannheim, University of Heidelberg. Heidelberg, Germany.

Context: Due to maldigestion, pancreatic exocrine insufficiency (PEI) in chronic pancreatitis may lead to deficiencies in fat-soluble vitamins, including vitamin D. This may, in turn, can cause disturbances in bone metabolism and reduce bone mineral density.

Objective: To conduct a prospective study of maldigestion, bone metabolism, and bone mineral density in a group of patients with chronic pancreatitis. Read More

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http://dx.doi.org/10.6092/1590-8577/2898DOI Listing
January 2015
14 Reads

Relationship between pain and plasma amino acid levels in chronic pancreatitis.

JOP 2015 Jan 31;16(1):53-7. Epub 2015 Jan 31.

Tokai University School of Medicine. Isehara, Japan.

Objective: Our aim was to investigate the relationship between imbalances of plasma amino acids and pain in chronic pancreatitis (CP).

Methods: Thirty patients with alcoholic CP in an exocrine-insufficient state were examined. We divided them between diet and control group. Read More

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http://dx.doi.org/10.6092/1590-8577/2897DOI Listing
January 2015
4 Reads