72,306 results match your criteria JAMA : the journal of the American Medical Association[Journal]


Addressing Medicine's Bias Against Patients Who Are Overweight.

Authors:
Rita Rubin

JAMA 2019 Feb 20. Epub 2019 Feb 20.

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http://dx.doi.org/10.1001/jama.2019.0048DOI Listing
February 2019

Abdominal Pain and Vomiting in a Pregnant Woman Who Has Had a Gastric Bypass Procedure.

JAMA 2019 Feb 20. Epub 2019 Feb 20.

Southern California Permanente Medical Group, Fontana.

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http://dx.doi.org/10.1001/jama.2017.18946DOI Listing
February 2019

Hydroxyurea Safe and Effective for Sickle Cell Anemia.

Authors:
M J Friedrich

JAMA 2019 Feb;321(7):637

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http://dx.doi.org/10.1001/jama.2019.0592DOI Listing
February 2019

Yemen's Deadly Cholera Epidemic.

Authors:
M J Friedrich

JAMA 2019 Feb;321(7):637

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http://dx.doi.org/10.1001/jama.2019.0151DOI Listing
February 2019

Promoting Sensible Parenting Policies: Leading by Example.

Authors:
Rebekah Diamond

JAMA 2019 Feb;321(7):645-646

Division of Child and Adolescent Health, Department of Pediatrics, Columbia College of Physician and Surgeons, New York, New York.

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http://dx.doi.org/10.1001/jama.2019.0460DOI Listing
February 2019

Surgical Decision Making for Older Adults.

JAMA 2019 Feb;321(7):716

VA Greater Los Angeles Healthcare, Los Angeles, California.

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http://dx.doi.org/10.1001/jama.2019.0283DOI Listing
February 2019

Effect of Intravenous Acetaminophen vs Placebo Combined With Propofol or Dexmedetomidine on Postoperative Delirium Among Older Patients Following Cardiac Surgery: The DEXACET Randomized Clinical Trial.

JAMA 2019 Feb;321(7):686-696

Department of Medicine, Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Importance: Postoperative delirium is common following cardiac surgery and may be affected by choice of analgesic and sedative.

Objective: To evaluate the effect of postoperative intravenous (IV) acetaminophen (paracetamol) vs placebo combined with IV propofol vs dexmedetomidine on postoperative delirium among older patients undergoing cardiac surgery.

Design, Setting, And Participants: Randomized, placebo-controlled, factorial clinical trial among 120 patients aged 60 years or older undergoing on-pump coronary artery bypass graft (CABG) surgery or combined CABG/valve surgeries at a US center. Read More

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http://dx.doi.org/10.1001/jama.2019.0234DOI Listing
February 2019
1 Read

Assessment of the FDA Risk Evaluation and Mitigation Strategy for Transmucosal Immediate-Release Fentanyl Products.

JAMA 2019 Feb;321(7):676-685

Center for Drug Safety and Effectiveness, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Importance: Transmucosal immediate-release fentanyls (TIRFs), indicated solely for breakthrough cancer pain in opioid-tolerant patients, are subject to a US Food and Drug Administration (FDA) Risk Evaluation and Mitigation Strategy (REMS) to prevent them from being prescribed inappropriately.

Objectives: To evaluate knowledge assessments of pharmacists, prescribers, and patients regarding appropriate TIRF use; to describe sponsor assessments, based on claims data, of whether the REMS program was meeting its goals; and to characterize how the FDA responded to REMS assessments.

Design, Setting, And Participants: Qualitative analysis of 4877 pages of FDA documents obtained through a Freedom of Information Act request, including 6 annual REMS assessment reports (2012-2017), FDA evaluations of these reports, and FDA-sponsor correspondence about safety issues. Read More

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http://dx.doi.org/10.1001/jama.2019.0235DOI Listing
February 2019

Gestational Diabetes and Childhood Obesity-Reply.

JAMA 2019 Feb;321(7):708-709

Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1001/jama.2018.19754DOI Listing
February 2019

Long-term Follow-up of Antibiotics vs Surgery for Appendicitis-Reply.

JAMA 2019 Feb;321(7):707-708

Department of Biostatistics, University of Turku, Turku, Finland.

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http://dx.doi.org/10.1001/jama.2018.19595DOI Listing
February 2019

Gestational Diabetes and Childhood Obesity.

JAMA 2019 Feb;321(7):708

Imperial College London School of Medicine, London, England.

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http://dx.doi.org/10.1001/jama.2018.19750DOI Listing
February 2019

Long-term Follow-up of Antibiotics vs Surgery for Appendicitis.

JAMA 2019 Feb;321(7):706

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

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http://dx.doi.org/10.1001/jama.2018.19591DOI Listing
February 2019

Long-term Follow-up of Antibiotics vs Surgery for Appendicitis.

Authors:
Nicholas L Syn

JAMA 2019 Feb;321(7):706-707

Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.1001/jama.2018.19588DOI Listing
February 2019
47.661 Impact Factor

Weather and Disease.

Authors:

JAMA 2019 Feb;321(7):712

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http://dx.doi.org/10.1001/jama.2018.15209DOI Listing
February 2019

Medical Scribes, Productivity, and Satisfaction.

JAMA 2019 Feb;321(7):635-636

Director, Partnered Evidence-based Policy Resource Center, Veterans Health Administration.

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http://dx.doi.org/10.1001/jama.2019.0268DOI Listing
February 2019

FDA Approves Bacteriophage Trial.

Authors:
Rebecca Voelker

JAMA 2019 Feb;321(7):638

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http://dx.doi.org/10.1001/jama.2019.0510DOI Listing
February 2019

Error in Introduction.

Authors:

JAMA 2019 Feb;321(7):709

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http://dx.doi.org/10.1001/jama.2019.0541DOI Listing
February 2019

Incomplete Funding.

Authors:

JAMA 2019 Feb;321(7):709

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http://dx.doi.org/10.1001/jama.2019.0152DOI Listing
February 2019

Whipped Cream-Viennese Ballet and Pop Surrealism Meet Dark Medicine.

JAMA 2019 Feb;321(7):630-631

Department of Music, Princeton University, Princeton, New Jersey.

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http://dx.doi.org/10.1001/jama.2018.19502DOI Listing
February 2019

Addressing the Psychological Symptoms of Critical Illness: The Importance of "Negative" Trials in Guiding Next Steps.

JAMA 2019 Feb;321(7):649-650

Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle.

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http://dx.doi.org/10.1001/jama.2019.0072DOI Listing
February 2019

Effect of a Nurse-Led Preventive Psychological Intervention on Symptoms of Posttraumatic Stress Disorder Among Critically Ill Patients: A Randomized Clinical Trial.

JAMA 2019 Feb;321(7):665-675

Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, United Kingdom.

Importance: A meta-analysis of outcomes during the 6 months after intensive care unit (ICU) discharge indicate a prevalence for clinically important posttraumatic stress disorder (PTSD) symptoms of 25%.

Objective: To determine whether a nurse-led preventive, complex psychological intervention, initiated in the ICU, reduces patient-reported PTSD symptom severity at 6 months.

Design, Setting, And Participants: A multicenter, parallel-group, cluster-randomized clinical trial with integrated economic and process evaluations conducted in 24 ICUs in the United Kingdom. Read More

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http://dx.doi.org/10.1001/jama.2019.0073DOI Listing
February 2019

The Elusive Search for "Best PEEP" and Whether Esophageal Pressure Monitoring Helps.

JAMA 2019 Feb 18. Epub 2019 Feb 18.

Department of Intensive Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil.

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http://dx.doi.org/10.1001/jama.2019.0267DOI Listing
February 2019

Effect of Titrating Positive End-Expiratory Pressure (PEEP) With an Esophageal Pressure-Guided Strategy vs an Empirical High PEEP-Fio2 Strategy on Death and Days Free From Mechanical Ventilation Among Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.

JAMA 2019 Feb 18. Epub 2019 Feb 18.

Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Importance: Adjusting positive end-expiratory pressure (PEEP) to offset pleural pressure might attenuate lung injury and improve patient outcomes in acute respiratory distress syndrome (ARDS).

Objective: To determine whether PEEP titration guided by esophageal pressure (PES), an estimate of pleural pressure, was more effective than empirical high PEEP-fraction of inspired oxygen (Fio2) in moderate to severe ARDS.

Design, Setting, And Participants: Phase 2 randomized clinical trial conducted at 14 hospitals in North America. Read More

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http://dx.doi.org/10.1001/jama.2019.0555DOI Listing
February 2019

How Best to Resuscitate Patients With Septic Shock?

Authors:
Derek C Angus

JAMA 2019 Feb;321(7):647-648

University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2019.0070DOI Listing
February 2019

Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial.

JAMA 2019 Feb;321(7):654-664

Departmento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago.

Importance: Abnormal peripheral perfusion after septic shock resuscitation has been associated with organ dysfunction and mortality. The potential role of the clinical assessment of peripheral perfusion as a target during resuscitation in early septic shock has not been established.

Objective: To determine if a peripheral perfusion-targeted resuscitation during early septic shock in adults is more effective than a lactate level-targeted resuscitation for reducing mortality. Read More

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http://dx.doi.org/10.1001/jama.2019.0071DOI Listing
February 2019

The Orphan Drug Act Revisited.

JAMA 2019 Feb 15. Epub 2019 Feb 15.

Division of Medical Ethics, NYU Langone Medical Center, New York, New York.

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http://dx.doi.org/10.1001/jama.2019.0290DOI Listing
February 2019

Patients and Physicians in the Era of Modern Cancer Care.

Authors:
George W Sledge

JAMA 2019 Feb 15. Epub 2019 Feb 15.

Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1001/jama.2018.17334DOI Listing
February 2019

The 2018 Farm Bill-Implications and Opportunities for Public Health.

JAMA 2019 Feb 15. Epub 2019 Feb 15.

Friedman School of Nutrition Science & Policy, Tufts University, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2019.0317DOI Listing
February 2019

Enterovirus D68-Associated Acute Flaccid Myelitis: Rising to the Clinical and Research Challenges.

JAMA 2019 Feb 15. Epub 2019 Feb 15.

Neuroinfectious Disease Section, Department of Neurology, University of Colorado, Aurora.

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http://dx.doi.org/10.1001/jama.2019.1016DOI Listing
February 2019
2 Reads

Next-Generation Sequencing of Infectious Pathogens.

JAMA 2019 Feb 14. Epub 2019 Feb 14.

Office of Advanced Molecular Detection, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.

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http://dx.doi.org/10.1001/jama.2018.21669DOI Listing
February 2019

Diagnosis and Management of Infectious Diarrhea.

JAMA 2019 Feb 14. Epub 2019 Feb 14.

University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1001/jama.2018.21974DOI Listing
February 2019

Hospitals Turn to Housing to Help Homeless Patients.

Authors:
Bridget M Kuehn

JAMA 2019 Feb 13. Epub 2019 Feb 13.

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http://dx.doi.org/10.1001/jama.2018.21476DOI Listing
February 2019

Contaminated Bypass Equipment.

Authors:
Bridget Kuehn

JAMA 2019 Feb;321(6):538

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http://dx.doi.org/10.1001/jama.2019.0190DOI Listing
February 2019
1 Read

Wound Botulism Outbreak.

Authors:
Bridget Kuehn

JAMA 2019 Feb;321(6):538

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http://dx.doi.org/10.1001/jama.2019.0050DOI Listing
February 2019

Interventions to Prevent Perinatal Depression: US Preventive Services Task Force Recommendation Statement.

JAMA 2019 02;321(6):580-587

Tufts University, Medford, Massachusetts.

Importance: Perinatal depression, which is the occurrence of a depressive disorder during pregnancy or following childbirth, affects as many as 1 in 7 women and is one of the most common complications of pregnancy and the postpartum period. It is well established that perinatal depression can result in adverse short- and long-term effects on both the woman and child.

Objective: To issue a new US Preventive Services Task Force (USPSTF) recommendation on interventions to prevent perinatal depression. Read More

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http://dx.doi.org/10.1001/jama.2019.0007DOI Listing
February 2019
1 Read
35.289 Impact Factor

Interventions to Prevent Perinatal Depression: Evidence Report and Systematic Review for the US Preventive Services Task Force.

JAMA 2019 02;321(6):588-601

University of North Carolina at Chapel Hill School of Medicine.

Importance: Depression during pregnancy and the postpartum period is relatively common and can have adverse effects on both mother and child.

Objective: To systematically review benefits and harms of primary care-relevant interventions to prevent perinatal depression, a major or minor depressive episode during pregnancy or up to 1 year after childbirth, to inform the US Preventive Services Task Force.

Data Sources: MEDLINE, PubMED (for publisher-supplied records only), PsycINFO, and the Cochrane Central Register of Controlled Trials; surveillance through December 5, 2018. Read More

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2018.20865DOI Listing
February 2019
6 Reads

Permanent Ink.

Authors:
Paige Luneburg

JAMA 2019 Feb;321(6):545-546

Departments of Internal Medicine and Pediatrics, University of Maryland School of Medicine, Baltimore.

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http://dx.doi.org/10.1001/jama.2019.0242DOI Listing
February 2019

Counseling Interventions to Prevent Perinatal Depression.

Authors:
Jill Jin

JAMA 2019 02;321(6):620

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http://dx.doi.org/10.1001/jama.2019.0253DOI Listing
February 2019

Association of Left Ventricular Ejection Fraction and Symptoms With Mortality After Elective Noncardiac Surgery Among Patients With Heart Failure.

JAMA 2019 02;321(6):572-579

Division of General Surgery, Palo Alto Veterans Affairs Health Care System, Palo Alto, California.

Importance: Heart failure is an established risk factor for postoperative mortality, but how left ventricular ejection fraction and heart failure symptoms affect surgical outcomes is not fully described.

Objectives: To determine the risk of postoperative mortality among patients with heart failure at various levels of echocardiographic (left ventricular systolic dysfunction) and clinical (symptoms) severity compared with those without heart failure and to evaluate how risk varies across levels of surgical complexity.

Design, Setting, And Participants: US multisite retrospective cohort study of all adult patients receiving elective, noncardiac surgery in the Veterans Affairs Surgical Quality Improvement Project database from 2009 through 2016. Read More

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http://dx.doi.org/10.1001/jama.2019.0156DOI Listing
February 2019

Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.

JAMA 2019 02;321(6):562-571

Centre of Anaesthesiological Research, Department of Anesthesiology, Zealand University Hospital, Køge, Denmark.

Importance: Multimodal postoperative analgesia is widely used but lacks evidence of benefit.

Objective: Investigate beneficial and harmful effects of 4 nonopioid analgesics regimens.

Design, Setting, And Participants: Randomized, blinded, placebo-controlled, 4-group trial in 6 Danish hospitals with 90-day follow-up that included 556 patients undergoing total hip arthroplasty (THA) from December 2015 to October 2017. Read More

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http://dx.doi.org/10.1001/jama.2018.22039DOI Listing
February 2019

Antibiotics for Ceftriaxone Resistant Gram-Negative Bacterial Bloodstream Infections-Reply.

JAMA 2019 02;321(6):613

University of Queensland Centre for Clinical Research, Brisbane, Australia.

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http://dx.doi.org/10.1001/jama.2018.19353DOI Listing
February 2019

Age of Initiation of Cervical Cancer Screening-Reply.

JAMA 2019 02;321(6):612

Veterans Affairs Palo Alto Health Care System, Palo Alto, California.

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http://dx.doi.org/10.1001/jama.2018.19089DOI Listing
February 2019

Antibiotics for Ceftriaxone-Resistant Gram-Negative Bacterial Bloodstream Infections.

JAMA 2019 02;321(6):613

Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1001/jama.2018.19349DOI Listing
February 2019