343,287 results match your criteria Italian Journal of Pediatrics [Journal]


Cytological and molecular aspects of the ageing sperm.

Hum Reprod 2018 Dec 14. Epub 2018 Dec 14.

Laboratory of Seminology - Sperm Bank 'Loredana Gandini' Department of Experimental Medicine, 'Sapienza' University of Rome, Italy.

Study Question: Is ageing associated with a decline in semen quality and molecular changes to human sperm?

Summary Answer: Semen quality declines with advancing age and characteristic molecular changes take place during the ageing process, including increased sperm DNA damage, altered sperm protamination and altered seminal plasma miRNA profile.

What Is Known Already: During ageing, the reproductive system is exposed to physiological changes and potentially damaging factors that may impair testicular function. Reactive oxygen species (ROS) can induce errors during DNA replication, transcription or post-transcriptional events (fragmentation, chromatin condensation abnormalities and protamine expression defects). Read More

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December 2018

Low dose of aPCC after the initial treatment in acquired haemophilia A is useful to reduce bleeding relapses: Data from the FAIR registry.

Thromb Res 2018 Dec 6;174:24-26. Epub 2018 Dec 6.

Haemophilia and Thrombosis Centre, S.Giovanni Bosco Hospital of Naples, Italy.

Background: Bypassing agents are the first line therapy in patients with acquired haemophilia A (AHA). Activated prothrombin complex concentrate (aPCC) proved to be effective as initial treatment, but 20% of patients (pts) had relapses. aPCC as short-term prophylaxis to reduce subsequent bleeds is still not clear. Read More

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December 2018
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Development and initial validation of the Positive Sexuality Scale for female adults.

Authors:
Giulia Casu

J Clin Nurs 2018 Dec 14. Epub 2018 Dec 14.

Department of Psychology, University of Bologna, Bologna, Italy.

Aim And Objectives: To develop and initially validate the Positive Sexuality Scale (PSS) to assess adult female positive sexuality.

Background: While traditional approaches focus on negative sexual experiences and sexual dysfunctions, within the positive psychology framework positive sexuality is a subjective experience of happiness and fulfillment with one's sexual expression, which contributes to well-being. No measure exists that specifically measures adult female positive sexuality and can be confidently used with women of any fertility/childlessness status. Read More

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December 2018
1 Read

Sentinel hospital-based surveillance for norovirus infection in children with gastroenteritis between 2015 and 2016 in Italy.

PLoS One 2018 14;13(12):e0208184. Epub 2018 Dec 14.

Dipartimento di Scienze Biomediche e Oncologia Umana, Università Aldo Moro di Bari, Bari, Italy.

Noroviruses are one of the leading causes of gastro-enteric diseases worldwide in all age groups. Novel epidemic noroviruses with GII.P16 polymerase and GII. Read More

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December 2018
1 Read

[Preliminary results of a cognitive survey among the members of the Italian Medical Radiation Protection Society(AIRM): from characterization of the professional activity to identification of training needs].

G Ital Med Lav Ergon 2018 Dec;40(4):224-247

Consiglio Nazionale delle Ricerche and Consiglio Direttivo AIRM.

Objectives: For several decades, the Italian Association of Medical Radioprotection (AIRM) is engaged in the promotion of scientific, technical, and methodological knowledge in the field of medical radioprotection.

Methods: Starting from the results of the previous study conducted in 2013, AIRM has carried out a new survey among its members. This survey was carried out through a self-administered questionnaire to be completed online on a platform set up on the association's website. Read More

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December 2018

[Analysis of the working population applying to the clinic for the psycological job environmental discomfort relating to employment at AUSL of Romagna - Rimini].

G Ital Med Lav Ergon 2018 Dec;40(4):217-223

U.O.C. Sistemi per la Salute e Sicurezza dei Lavoratori, AUSL Romagna - Rimini.

Objectives: The Occupational Physician in accordance with the Prevention and Protection of AUSL Romagna (Rimini) has enabled for some years, a Clinic for the psychological job environmental discomfort addressed to employment, with expressions of the psychophysical disorders, caused by work related stress. Health is defined by the current legislation as a state of psychophysical and social wellbeing.

Methods: The main purpose of Clinic for the psychological distress in working environment is to provide listening space and psychological support for employees. Read More

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December 2018

[The role of agentic capacities in turnover intentions among nurses].

G Ital Med Lav Ergon 2018 Dec;40(4):208-216

Dipartimento di Pedagogia, Psicologia, Filosofia, Università di Cagliari, Italia.

Objectives: Voluntary turnover in the nursing profession is one of the main concerns in hospitals and it requests comprehensive research. This study contributes to explain the reasons related to turnover intention of nurses and provides causes for reflection to improve the working practice.

Methods: 161 nurses and 13 nursing coordinators, working in the wards of two Italian hospitals, participated in the study. Read More

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December 2018

[Manual handling, job fitness, and musculoskeletal disorders in the Sondrio hospital (Italy) healthcare workers.]

G Ital Med Lav Ergon 2018 Dec;40(4):203-207

Dipartimento di Sanità Pubblica, Medicina Sperimentale e Forense, Sezione di Medicina del Lavoro, Università degli Studi di Pavia and Unità Operativa di Medicina del Lavoro, Istituti Clinici Scientifici Maugeri IRCCS, Pavia.

Objectives: Musculo-skeletal disorders (MSD) are a large group of locomotor system pathologies with multifactorial etiology. Healthcare professionals are often exposed to biomechanical overload of the spine and upper limb, for example during patient handling, and represent a working population at risk.

Methods: In order to acquire further knowledge on this subject, we conducted a cross-sectional study (year 2016) among healthcare workers (excluding physicians) of the Sondrio Hospital (Italy), investigating the correlations between manual handling, MDS and job fitness. Read More

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December 2018

[Biological risk in agriculture and construction workplaces: a survey on perception, knowledge and prevention measures.]

G Ital Med Lav Ergon 2018 Dec;40(4):195-202

Cattedra di Igiene, Dipartimento di Medicina e Scienze per la Salute "Vincenzo Tiberio", Università degli Studi del Molise.

Objectives: Despite the potential presence in many workplaces, biological risk is little known and largely underestimated, except in healthcare environments. Objectives: To evaluate perception, knowledge and behaviors adopted for protection and prevention of biological risk, related also to the occupational activity, among construction and agricultural workers.

Methods: Workers were recruited at farms and construction companies of Molise Region, Central Italy, which were visited within the surveillance activities planned by local institutions. Read More

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December 2018

[Records of processing activities].

Authors:
Filippo Lorè

G Ital Nefrol 2018 Dec;35(6)

Università degli Studi di Bari.

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December 2018

[CRIMINAL RESPONSIBILITY OF MEDICAL AND ITS CASE LAW EVOLUTION. LEGAL AND ECONOMIC PROFILES].

Authors:
Antonio Capasso

G Ital Nefrol 2018 Dec;35(6)

Dottore in giurisprudenza, Cultore della materia Università Federico II Napoli.

The article deals with the regulatory and jurisprudential evolution of medical criminal responsibility from the 70s to the Gelli-Bianco law of 2017. Subsequently it winds through the contribution of the last important judgments of the subject up to the decisions of the Supreme Court with United Sections of 2018, finally to conclude with an economic analysis on the increasement of the legal disputes registered in recent years. Read More

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December 2018

[Artificial intelligence for future MD].

G Ital Nefrol 2018 Dec;35(6)

Psicologa Clinica, Psicoterapeuta Sistemico Relazionale IIPR, Psicologa Clinica Ismett, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione - IRCCS, Palermo.

Health care workers need artificial intelligence. Artificial intelligence is a set of studies and techniques that tend to the realization of machines, which solve complex problems automatically, simulating or emulating human intelligence activities. Human intelligence is innate, creative, emotional, sporting, social in the collective and connected future. Read More

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December 2018

[The Good Samaritan Donor Experience].

G Ital Nefrol 2018 Dec;35(6)

Psicologa Clinica, Psicoterapeuta Sistemico Relazionale IIPR, Psicologa Clinica Ismett, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione - IRCCS, Palermo.

The need for patients with a chronic kidney failure and on dialysis to embark on a kidney transplant process, poses the challenge to identify alternative and effective surgical strategies to overcome the insufficient number of deceased donors. The purpose is to allow the considerable number of patients on the kidney transplant waiting lists to receive appropriate treatment in time and under the most favorable clinical conditions. Living donation from a significant other is becoming increasingly widespread, on a national and international level. Read More

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December 2018

[Efficacy of SUPRA HFR in the treatment of acute renal damage during multiple myeloma].

G Ital Nefrol 2018 Dec;35(6)

S.C. Nefrologia, Dialisi e Trapianto U. AOU Città della Salute e della Scienza di Torino, Torino, Italia.

Acute Kidney Injury (AKI) is a frequent complication of multiple myeloma (MM) with unfavorable prognostic significance. Light chains removal, combined with hematological therapy (CT) seems to offer significant benefits to renal function recovery (RFR). The SUPRA HFR, through the combination of high cut-off membrane without albumin loss and adsorbent cartridge, represents one of the "emerging" light chain removal methods. Read More

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December 2018

[Acute kidney injury as a risk marker for hospital readmission: a single-center pilot study in the general population of the Parma area].

G Ital Nefrol 2018 Dec;35(6)

Unità di Fisiopatologia dell'Insufficienza Renale Acuta e Cronica - Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma.

Acute Kidney Injury (AKI) is an important issue for the healthcare system, as it is associated with high mortality and increased risk of readmission, with consequent elevated healthcare resource utilization. We investigated the incidence of AKI based on the examination of the discharge cards of all patients admitted between January 1 2011 and December 31 2015 at the Parma University Hospital, as well as the frequency and type of 30-day hospital readmission in the patients discharged with a first AKI diagnosis (index admission). The mean pooled 5-year incidence of AKI was 2. Read More

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December 2018

[Hemodialysis treatment as a trigger cause of cryoglobulinemic purpura: a case report].

G Ital Nefrol 2018 Dec;35(6)

U.O.C. Nefrologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, ROMA.

We describe the clinical case of a patient who developed mixed cryoglobulinemia syndrome after hemodialysis treatment with dialysate temperature lower than 36°C despite the negativization of the viral genome for HCV after eradication therapy. Read More

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December 2018

[Retroperitoneal renal hemorrhage: experience of our dialysis center].

G Ital Nefrol 2018 Dec;35(6)

ASST-Ovest Milanese - Ospedale Magenta e Legnano, Milano.

The aging of the uremic population, the increasingly common use of anticoagulants, antiplatelet agents e heparin, during hemodialysis, can expose our patients to a greatest risk of bleeding. Spontaneous retroperitoneal hematomas are a fairly rare and potentially fatal condition. We describe 5 clinical cases of retroperitoneal hemorrhage that we observed during 10 years in our department, focusing on modalities of symptom onset, clinical-laboratory picture and treatment modalities. Read More

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December 2018

[FSGS collapsing variant during anabolic steroid abuse: Case Report].

G Ital Nefrol 2018 Dec;35(6)

UO Nefrologia e Dialisi AUSL Romagna Ospedale Infermi Rimini.

Anabolic Androgenic Steroids (AAS) is an hormone family whose use has considerably increased among body-builders during the last decades. The AAS abuse, especially associated with other drugs or nutritional supplements and protein loads, may cause a variety of pathologies to several organs with a mechanism related to dosage, timing and substance. The kidney is the main metabolizer of these drugs and it can be acutely or chronically damaged with ESKD. Read More

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December 2018

[The pathway of vasopressin as a pharmacological target in nephrology: a narrative review].

G Ital Nefrol 2018 Dec;35(6)

U.O.C. Nefrologia, Università cattolica del sacro cuore. Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.

ADH is a hormone secreted by neurohypophysis that plays different roles based on the target organ. At the renal level, this peptide is capable of causing electrolyte-free water absorption, thus playing a key role in the hydro-electrolytic balance. There are pathologies and disorders that jeopardize this balance and, in this field, ADH receptor inhibitors such as Vaptans could play a key role. Read More

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December 2018

[PHYSICAL, CHEMICAL AND MORPHOLOGICAL URINE EXAMINATION: RECOMMENDATIONS FOR THE POST ANALYTICAL PHASE FROM THE INTERDISCIPLINARY URINALYSIS GROUP (GIAU)].

G Ital Nefrol 2018 Dec;35(6)

Cattedra Nefrologia Università degli Studi di Bari-Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari.

With these recommendations the Interdisciplinary Urinalysis Group (GIAU) aims to stimulate the following aspects : improvement and standardization of the post analytical approach to physical, chemical and morphological urine examination (ECMU); emphasize the value added to ECMU by selection of clinically significant parameters, indication of analytical methods, of units of measurement, of reference values; improvement of interpretation of dip stick urinalysis with particular regard to the reconsideration of the diagnostic significance of the evaluated parameters together with an increasing awareness of the limits of sensitivity and specificity of this analytical method. Accompanied by the skills to propose and carry out in-depth investigations with analytical methods that are more sensitive and specific;increase the awareness of the importance of professional skills in the field of urinary morphology and their relationships with the clinicians. through the introduction, in the report, of descriptive and interpretative comments depending on the type of request, the complexity of the laboratory, the competence of the pathologist;implement a policy of evaluation of the analytical quality by using, in addition to traditional internal and external controls, a program for the evaluation of morphological competence. Read More

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December 2018

[Methodology for determining workforce in health nephrologic unit in ITALY. Update of lows].

G Ital Nefrol 2018 Dec;35(6)

Membro del Direttivo SIN, esperto di organizzazione sanitaria, ex responsabile controllo di gestione ospedale di Perugia, ex coordinatore governo clinico SIN.

Nephrology continues to be in transition. While rates of kidney diseases and injury continue to rise, changes in the general health care system and the delivery of kidney care make it unclear how increases in need will be translated into demand for nephrologists. The changes in the delivery system also raise questions as to the future roles and career paths for nephrologists. Read More

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December 2018

[Laws regulating transplantation should express the contemporaneity. Questions to the constitutionalist Francesco Paolo Casavola and to the philosophers Remo Bodei and Aldo Masullo about the possibility deciding the destiny of one's own organs at the time one decides on how to die and on contacts between donor families and recipients.]

G Ital Nefrol 2018 Dec;35(6)

Dipartimento di Scienze Mediche Traslazionali, Università della Campania Luigi Vanvitelli, Napoli.

Transplantation represents modernity thus the laws regulating the procedure should be continuously renovated and remodeled in order to take full advantage of progress. The debate is about Law no. 219, December 22, 2017 and on Law no. Read More

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December 2018

[Editorial].

Authors:
Biagio Di Iorio

G Ital Nefrol 2018 Dec;35(6)

Unità Complessa di Nefrologia AORN Ospedale Cardarelli, Napoli.

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December 2018

DNA damage signatures in peripheral blood cells (PBMC) as biomarkers in prodromal Huntington's disease.

Ann Neurol 2018 Dec 14. Epub 2018 Dec 14.

Department of Biology, University of Naples "Federico II", Naples, Italy.

Easily accessible biomarkers in Huntington disease (HD) are actively searched. We investigated telomere length (TL) and DNA double-strand breaks (histone variant pγ-H2AX) as predictive disease biomarkers in peripheral blood mononuclear cells (PBMC) from 25 pre-manifest, 58 HD patients, with similar CAG expansion in the huntingtin gene (HTT) gene and 44 healthy controls (HC). PBMC from PRE-HD and HD groups showed shorter telomeres (p<0. Read More

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December 2018

Climate change impact and adaptation for wheat protein.

Glob Chang Biol 2019 Jan 22;25(1):155-173. Epub 2018 Nov 22.

Institute of Crop Science and Resource Conservation INRES, University of Bonn, Bonn, Germany.

Wheat grain protein concentration is an important determinant of wheat quality for human nutrition that is often overlooked in efforts to improve crop production. We tested and applied a 32-multi-model ensemble to simulate global wheat yield and quality in a changing climate. Potential benefits of elevated atmospheric CO concentration by 2050 on global wheat grain and protein yield are likely to be negated by impacts from rising temperature and changes in rainfall, but with considerable disparities between regions. Read More

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January 2019
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Circulating miRNA-375 as a potential novel biomarker for active Kaposi's sarcoma in AIDS patients.

J Cell Mol Med 2018 Dec 13. Epub 2018 Dec 13.

Immunology and Molecular Oncology, Veneto Institute of Oncology IOV - IRCCS, Padova, Italy.

The aim of this study was to identify circulating microRNAs (miRNAs) that could be used as biomarkers in patients at risk for or affected by AIDS-Kaposi's sarcoma (KS). Screening of 377 miRNAs was performed using low-density arrays in pooled plasma samples of 10 HIV/human herpesvirus 8 (HHV8)-infected asymptomatic and 10 AIDS-KS patients before and after successful combined antiretroviral therapy (cART). MiR-375 was identified as a potential marker of active KS, being the most down-regulated in AIDS-KS patients after cART and the most up-regulated in naïve AIDS-KS patients compared to naïve asymptomatic subjects. Read More

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December 2018
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Tetrasomy 18p: The challenges of noninvasive prenatal testing and combined test.

J Obstet Gynaecol Res 2018 Dec 13. Epub 2018 Dec 13.

Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Circulating cell-free DNA, having no procedural risk of miscarriage, is the most suitable sample for a noninvasive prenatal testing (NIPT). Here we report on a boy, who came to our attention for hypotonia and psychomotor delay when he was 16 months old. During the pregnancy his mother performed a NIPT that resulted compatible with the presence of trisomy 18. Read More

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December 2018

Applicability of telemedicine in the screening of diabetic retinopathy (DR): The first multicentre study in Italy. The No Blind Study.

Diabetes Metab Res Rev 2018 Dec 13:e3113. Epub 2018 Dec 13.

Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.

Aims: Diabetic retinopathy (DR) represents the main cause of blindness among adults in the industrialized Countries. Use of telemedicine could offer an easy, smart specialist fundus oculi examination, as well as putting in a screening program many patients who otherwise would be excluded.

Materials And Methods: The NO Blind is a transversal, multicentre, observational study. Read More

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December 2018

Estimated glomerular filtration rate and all-cause mortality - In response to Dr Kawada's letter.

Geriatr Gerontol Int 2018 Dec;18(12):1655

Unit of Geriatric Medicine, University Campus Biomedico, Rome, Italy.

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December 2018

Novel GLI2 mutations identified in patients with Combined Pituitary Hormone Deficiency (CPHD): evidence for a pathogenic effect by functional characterization.

Clin Endocrinol (Oxf) 2018 Dec 12. Epub 2018 Dec 12.

Laboratory of Genetics, Department of Health Sciences, University of Eastern Piedmont, Novara, Italy.

Context: The Gli-family of zinc-finger transcription factors regulates the Sonic Hedgehog (Shh) signalling pathway that plays a key role in early pituitary and ventral forebrain development. Heterozygous GLI2 loss of function mutations in humans have been reported in holoprosencephaly (HPE), HPE-like phenotypes associated with pituitary anomalies and combined pituitary hormone deficiency with or without other extra pituitary findings.

Objective: The aim of this study was the search for GLI2 mutations in a cohort of Italian CPHD patients and the assessment of a pathogenic role for the identified variants through in vitro studies. Read More

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December 2018

Declining population trends of European mountain birds.

Glob Chang Biol 2018 Dec 11. Epub 2018 Dec 11.

Dachverband Deutscher Avifaunisten (DDA) e.V., Geschäftsstelle, Münster, Germany.

Mountain areas often hold special species communities, and they are high on the list of conservation concern. Global warming and changes in human land use, such as grazing pressure and afforestation, have been suggested to be major threats for biodiversity in the mountain areas, affecting species abundance and causing distribution shifts towards mountaintops. Population shifts towards poles and mountaintops have been documented in several areas, indicating that climate change is one of the key drivers of species' distribution changes. Read More

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December 2018

Alcohol consumption and hospitalization burden in an adult Italian population: prospective results from the Moli-sani study.

Addiction 2018 Dec 12. Epub 2018 Dec 12.

Department of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy.

Background And Aims: Epidemiological evidence on the impact of different alcohol drinking patterns on health-care systems or hospitalizations is sparse. We investigated how the different average volumes of alcohol consumed relate to all-cause and cause-specific hospitalizations.

Design: Prospective cohort study (baseline 2005-10) linked to a registry of hospital discharge records to identify hospitalizations at follow-up (December 2013). Read More

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December 2018

Prevalence of temporomandibular disorders and oral parafunctions in adolescents from public schools in Southern Italy.

Cranio 2018 Dec 14:1-6. Epub 2018 Dec 14.

b School of Orthodontics, Department of Neurosciences, Reproductive Sciences and Oral Sciences , University of Naples Federico II , Naples , Italy.

Objective: The aim of this cross-sectional epidemiologic study was to estimate the prevalence of temporomandibular disorders (TMDs) and oral parafunctions in Italian adolescents and to assess the associations between age, gender, oral habits, and TMD.

Methods: Three hundred sixty-one adolescents, aged 14-18 years, were examined for TMDs according to the Research Diagnostic Criteria for TMD. Furthermore, oral habits were explored by means of a written questionnaire. Read More

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December 2018

Left atrial myxoma development after radiofrequency ablation of an atrial flutter substrate.

J Cardiol Cases 2015 Apr 20;11(4):124-126. Epub 2015 Feb 20.

Geriatrics-Rehabilitative Department, Italian National Research Center on Aging (I.N.R.C.A.), Fermo, Italy.

A 51-year-old man developed symptoms (palpitations) related to a large left atrial mass attached to interatrial septum discovered by trans-thoracic heart ultrasonography. Six months earlier this patient had undergone radiofrequency ablation (RFA) of an atrial flutter substrate. The left atrial mass was removed surgically using cardiopulmonary bypass with disappearance of symptoms. Read More

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Sex Pheromones of Two Leafminer Species, Antispila oinophylla and Holocacista rivillei (Lepidoptera: Heliozelidae) Infesting Grapevine in Italy.

J Chem Ecol 2018 Dec 14. Epub 2018 Dec 14.

Department of Biology, Lund University, Sölvegatan 37, 223 62, Lund, Sweden.

Two heliozelid species, Antispila oinophylla van Nieukerken & Wagner and Holocacista rivillei (Stainton) severely infest Italian grapevines. The volatile pheromones from calling females were collected by solid phase micro extraction (SPME) and analyzed by gas chromatography with electroantennographic detection (GC-EAD). Two compounds from A. Read More

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December 2018

Violence in the Early Bronze Age. Diagnosis of skull lesions using anthropological, taphonomic and scanning electron microscopy techniques.

Forensic Sci Med Pathol 2018 Dec 13. Epub 2018 Dec 13.

Department of Humanities, University of Ferrara, Ferrara, Italy.

In this paper we present the study of a skull belonging to a young male from the Italian Bronze Age showing three perimortem injuries on the frontal and parietal bones; the peculiarity of the frontal injury is represented by its singular shape, which may be indicative of the weapon that caused the lesion. The aim of the present study is to examine the traumatic evidence in relation to possible etiological factors, in order to attempt to establish if the lesion occurred peri or post-mortem, and to evaluate if these traumatic injuries could be interpreted as an evidence of interpersonal violence, by combining anthropological, taphonomic and ESEM investigations. The combination of multidisciplinary methods of study can provide important new insights into inter-personal violence. Read More

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December 2018

Domestic Violence Between Childhood Incest and Re-victimization: A Study Among Anti-violence Centers in Italy.

Front Psychol 2018 28;9:2377. Epub 2018 Nov 28.

FISPPA Department, University of Padova, Padua, Italy.

The study focuses on a specific problem in the area of child sexual abuse (CSA), which is still under-researched: the relationship between incest and adult female re-victimization treatment within the ambit of domestic violence in Italian centers. About 112 anti-violence centers were contacted, but only 13 participated and only 16 psychologists were interviewed to reconstruct the biographies of 32 victims. The study aimed to examine if and how the service centers recognized and dealt with the problem of re-victimization among survivors based on psychologists' narrations. Read More

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November 2018

Effects of Reading Proficiency and of Base and Whole-Word Frequency on Reading Noun- and Verb-Derived Words: An Eye-Tracking Study in Italian Primary School Children.

Front Psychol 2018 28;9:2335. Epub 2018 Nov 28.

NeuroMI - Milan Centre for Neuroscience, Milan, Italy.

The aim of this study is to assess the role of readers' proficiency and of the base-word distributional properties on eye-movement behavior. Sixty-two typically developing children, attending 3, 4, and 5 grade, were asked to read derived words in a sentence context. Target words were nouns derived from noun bases (e. Read More

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November 2018
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A National Quality Assurance program for breast immunohistochemistry: an Italian perspective.

Pathologica 2018 Sep;110(2):83-91

Pathology Unit, A. Cardarelli Hospital, Naples, Italy.

A national project for the quality assessment of breast immunohistochemistry, involving 155 pathology laboratories distributed all over the Italian territory ( 19 regions), was carried out. The Project lasted one year from December 2014 to December 2015 and it was strongly supported by the Italian Society of Anatomic Pathology (SIAPEC/IAP). Proficiency tests were carried out by the Nordic Immunohistochemical Quality Control (NordiQC) organization. Read More

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September 2018

Physician-pharmacist collaborative practice and telehealth may transform hypertension management.

J Hum Hypertens 2018 Dec 13. Epub 2018 Dec 13.

Clinical Research Unit, Italian Institute of Telemedicine, Varese, Italy.

Community pharmacists play a crucial role in hypertension management and their intervention, mainly including education, medication monitoring, and reviewing, blood pressure (BP) measurement and cardiovascular risk factors tracking, have proved to enhance BP control and adherence to antihypertensive treatment. A multidisciplinary collaborative approach with the referring physician and a patient-centered model of care have been proved to be particularly effective for improving control of hypertension and promoting patients' health. The inclusion of telehealth in such model (the so-called telepharmacy) may expand the reach of the pharmacist's intervention and provide pharmacy operations and patient care at a distance with further benefits for hypertensive patients and their managing physicians. Read More

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December 2018

One can be some but some cannot be one: ERP correlates of numerosity incongruence are different for singular and plural.

Cortex 2018 Nov 3. Epub 2018 Nov 3.

Department of Neuroscience DNS, University of Padova, Padova, Italia; Romanisches Seminar, University of Zürich, Zürich, Switzerland.

Humans can communicate information on numerosity by means of number words (e.g., one hundred, a couple), but also through Number morphology (e. Read More

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November 2018
2 Reads

Extraction, Analysis, and Antioxidant Activity Evaluation of Phenolic Compounds in Different Italian Extra-Virgin Olive Oils.

Molecules 2018 Dec 8;23(12). Epub 2018 Dec 8.

Unit of Food Science and Nutrition, Department of Medicine, Università Campus Bio-Medico di Roma, via Álvaro del Portillo 21, 00128 Rome, Italy.

The analysis of phenolic compounds in extra virgin olive oils was carried out by high-performance liquid chromatography utilizing photodiode array and mass spectrometry detectors. The chromatographic profile of thirty samples from four Italian Regions highlighted the presence of secoiridoids, phenolic alcohols, flavonoids, and phenolic acid classes. A similar qualitative profile was observed with some differences in peak area and fifteen compounds were tentatively identified. Read More

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December 2018

Chromatographic Analyses, In Vitro Biological Activities, and Cytotoxicity of Cannabis sativa L. Essential Oil: A Multidisciplinary Study.

Molecules 2018 Dec 10;23(12). Epub 2018 Dec 10.

Department of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.

Due to renewed interest in the cultivation and production of Italian L., we proposed a multi-methodological approach to explore chemically and biologically both the essential oil and the aromatic water of this plant. We reported the chemical composition in terms of cannabinoid content, volatile component, phenolic and flavonoid pattern, and color characteristics. Read More

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December 2018

A Role of Tumor-Released Exosomes in Paracrine Dissemination and Metastasis.

Int J Mol Sci 2018 Dec 10;19(12). Epub 2018 Dec 10.

Department of Oncology and Molecular Medicine, National Institute of Health, Viale Regina Elena 299, 00161 Rome, Italy.

Metastatic diffusion is thought to be a multi-step phenomenon involving the release of cells from the primary tumor and their diffusion through the body. Currently, several hypotheses have been put forward in order to explain the origin of cancer metastasis, including epithelial⁻mesenchymal transition, mutagenesis of stem cells, and a facilitating role of macrophages, involving, for example, transformation or fusion hybridization with neoplastic cells. In this paradigm, tumor-secreted extracellular vesicles (EVs), such as exosomes, play a pivotal role in cell communications, delivering a plethora of biomolecules including proteins, lipids, and nucleic acids. Read More

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December 2018
1 Read

Intra-specific variability of stomatal sensitivity to vapour pressure deficit in Corylus avellana L.: A candidate factor influencing different adaptability to different climates?

J Plant Physiol 2018 Nov 22;232:241-247. Epub 2018 Nov 22.

Department of Sustainable Crop Production, Università Cattolica del Sacro Cuore, Via Emilia Parmense 84, 29122, Piacenza, Italy. Electronic address:

Stomatal conductance is regulated by many factors such as air vapour pressure deficit (D), which can be the pivotal one affecting leaf gas exchange in species particularly sensitive to D such as C. avellana. The aim of this work was to evaluate stomatal sensibility to D and to determine correlations with hydraulics characteristics of leaves in three genotypes of C. Read More

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November 2018

Community ambulation of stroke survivors at 6 months follow-up: an observational study on sociodemographic and sub-acute clinical indicators.

Eur J Phys Rehabil Med 2018 Dec 13. Epub 2018 Dec 13.

Department of Neurorehabilitation, IRCCS San Raffaele Pisana, Rome, Italy.

Background: Despite the importance of walking recovery in real life contexts, only 7% of stroke survivors at discharge from neuro-rehabilitation units recover independent walking in the community. However, studies on outcome indicators of walking ability restoration following stroke rarely regard the community ambulation.

Aim: To investigate how socio-demographic and sub-acute clinical characteristics of stroke survivors at admission and at discharge may predict a good participation in community walking activity 6 months post-stroke. Read More

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December 2018

A campaign aimed at increasing seasonal influenza vaccination coverage among post graduate medical residents in an Italian teaching hospital.

Hum Vaccin Immunother 2018 Dec 13. Epub 2018 Dec 13.

a Section of Hygiene - Institute of Public Health , Università Cattolica del Sacro Cuore , Roma , Italy.

We analysed the impact of several strategies aimed at increasing influenza immunisation rates among Medical Residents (MRs) of an Italian teaching Hospital. During the 2015-16 and 2016-17 influenza seasons we carried out several interventions: ambulatory doubling where vaccination was offered, ambulatory opening hour extension, email invitations, informative materials, forum theatre and vaccination campaign conference. In addition, during the 2016-17 the OSV was carried out: MRs who go to specific wards where they perform influenza immunisation counselling and eventually vaccinate the personnel. Read More

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December 2018

Clinical and genetic characterization of an Italian family with slow-channel syndrome.

Neurol Sci 2018 Dec 12. Epub 2018 Dec 12.

Department of Biology, University of Padova, Padova, Italy.

Introduction: The slow-channel congenital myasthenic syndrome (SCCMS) is a postsynaptic form of congenital myasthenic syndromes (CMSs), a clinically heterogeneous group of disorders caused by genetic defects leading to an abnormal signal transmission at the endplate.

Methods: We report clinical and molecular data of a multigenerational family in which the presentation of a progressive proximal-distal weakness with ocular involvement led to a number of different clinical diagnoses.

Results: A comprehensive genetic study which included whole-genome linkage analysis and whole-exome sequencing identified a heterozygous missense substitution (c. Read More

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December 2018

A norming study of high-quality video clips of pantomimes, emblems, and meaningless gestures.

Behav Res Methods 2018 Dec 12. Epub 2018 Dec 12.

Center for Mind/Brain Science (CIMeC), University of Trento, 38068, Rovereto, TN, Italy.

Recent years have witnessed a growing interest in behavioral and neuroimaging studies on the processing of symbolic communicative gestures, such as pantomimes and emblems, but well-controlled stimuli have been scarce. This study describes a dataset of more than 200 video clips of an actress performing pantomimes (gestures that mimic object-directed/object-use actions; e.g. Read More

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December 2018