302,408 results match your criteria Issues in Emerging Health Technologies [Journal]


Virtual Reality Simulation in Peritoneal Dialysis Training: The Beginning of a New Era.

Blood Purif 2018 Dec 6:1-5. Epub 2018 Dec 6.

Weltenmacher GmbH, VR Training-Application, Düsseldorf, Germany.

Background/aim: Peritonitis rates in peritoneal dialysis (PD) vary considerably not only across countries but also between centers in the same country. Patient education has been shown to significantly reduce infection rates but up till now training lacks standardization with patients being trained using different methods and media (e.g. Read More

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December 2018
3 Reads

Difficult Patient Behavior in Dialysis Facilities.

Blood Purif 2018 Dec 6:1-5. Epub 2018 Dec 6.

Difficult behavior exhibited by dialysis patients is a spectrum that includes nonadherence, verbal or physical abuse, and threatening acts. Such behaviors may lead to harmful consequences to the patient, other patients, the facility, and staff and can culminate in involuntary discharge. It is important to recognize that these "difficult behaviors" may be due to underlying psychosocial or medical issues, which places an onus on care providers to explore further. Read More

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December 2018
1 Read

Tobacco and cannabis co-use and interrelatedness among adults.

Addict Behav 2018 Nov 27;90:354-361. Epub 2018 Nov 27.

Medical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, USA.

Cannabis and tobacco co-use is prevalent, but consensus regarding the reasons for co-use among adults and the degree of interrelatedness between these substances is lacking. Reasons for co-use have been explored with younger users, but little data exists for more experienced users with entrenched patterns of co-use. The goal of this study was to examine characteristics and patterns of cannabis-tobacco co-use among adults in the Southeastern United States (US), where there is a legal landscape of generally restrictive cannabis legislation coupled with more permissive tobacco control compared to other US regions. Read More

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November 2018
1 Read

Using horizontal curve speed reduction extracted from the naturalistic driving study to predict curve collision frequency.

Accid Anal Prev 2018 Dec 3;123:190-199. Epub 2018 Dec 3.

Department of Civil Engineering, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, K1S5B6, Canada. Electronic address:

Many models have been developed to predict collision frequency and evaluate safety performance on horizontal curves. The approach used in data collection or some assumptions made in the analysis methodology might lead to inaccurate results. For example, manual data collection, equipment limitations, and field experiments involving monitoring driving behavior for a specific region for a short-term are potential sources of errors in data collection. Read More

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December 2018
1 Read

Water drop-surface interactions as the basis for the design of anti-fogging surfaces: Theory, practice, and applications trends.

Adv Colloid Interface Sci 2018 Nov 24;263:68-94. Epub 2018 Nov 24.

Laboratoire d'Ingénierie de Surface, Centre de Recherche sur les Matériaux Avancés, Département de Génie des Mines, de la Métallurgie et des Matériaux, Université Laval, 1065 Avenue de la médecine, Québec G1V 0A6, Canada; Centre de Recherche du Centre Hospitalier Universitaire de Québec, Hôpital St-François d'Assise, 10 rue de l'Espinay, Québec G1L 3L5, Canada. Electronic address:

Glass- and polymer-based materials have become essential in the fabrication of a multitude of elements, including eyeglasses, automobile windshields, bathroom mirrors, greenhouses, and food packages, which unfortunately mist up under typical operating conditions. Far from being an innocuous phenomenon, the formation of minute water drops on the surface is detrimental to their optical properties (e.g. Read More

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November 2018
1 Read

Body composition and sarcopenia: the next-generation of personalized oncology and pharmacology?

Pharmacol Ther 2018 Dec 3. Epub 2018 Dec 3.

Department of Medical Oncology, CAncer Research for PErsonalized Medicine (CARPEM), Paris Centre Teaching Hospitals, Paris Descartes University, USPC, Paris, France.

Body composition has gained increasing attention in oncology in recent years due to fact that sarcopenia has been revealed to be a strong prognostic indicator for survival across multiple stages and cancer types and a predictive factor for toxicity and surgery complications. Accumulating evidence over the last decade has unraveled the "pharmacology" of sarcopenia. Lean body mass may be more relevant to define drug dosing than the "classical" body surface area or flat-fixed dosing in patients with cancer. Read More

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December 2018
2 Reads

Electronic "Sniffer" Systems to Identify the Acute Respiratory Distress Syndrome: A Systematic Review.

Ann Am Thorac Soc 2018 Dec 6. Epub 2018 Dec 6.

University of Michigan, Internal Medicine, Ann Arbor, Michigan, United States ;

Background: The acute respiratory distress syndrome (ARDS) results in substantial mortality but remains underdiagnosed in clinical practice. Automated ARDS "sniffer" systems, tools that can automatically analyze electronic medical record data, have been developed to improve recognition of ARDS in clinical practice.

Objective: To perform a systematic review examining the evidence underlying automated sniffer systems for ARDS detection. Read More

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December 2018

Supportive Care Network: Evaluation of Its Impact on the Performance of a Urology Department.

Acta Med Port 2018 Nov 30;31(11):656-660. Epub 2018 Nov 30.

Urology and Renal Transplantation Department. Coimbra University Hospital Center. Coimbra. Portugal.

Introduction: Hospitals are dealing with patients who may have clinical discharge but cannot return to their home due to non-medical issues.

Material And Methods: Cross-sectional analysis of all the cases referred to the Integrated Care Network during the year 2016. Evaluation of waiting times, typology, reason for referral and clinical parameters. Read More

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November 2018
1 Read

A comprehensive review of significant issues in health law.

Authors:
Andrew Alston

Med J Aust 2018 Dec;209(11):488

Flinders University, Adelaide, SA

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December 2018

Review of Haploidentical Hematopoietic Cell Transplantation.

J Glob Oncol 2018 Dec(4):1-13

Mehreen A. Khan, Qamar-un-Nisa Chaudhry, Tariq M. Satti, and Syed K. Mahmood, Armed Forces Bone Marrow Transplant Centre/National Institute of Blood and Marrow Transplant, Rawalpindi; Parvez Ahmed, Quaid-e-Azam International Hospital, Islamabad, Pakistan; and Qaiser Bashir, MD Anderson Cancer Centre, Houston, TX.

Use of haploidentical (haplo) donors for hematopoietic cell transplantation (HCT) has significantly increased in the last decade. The major advantage with this strategy is universal availability and faster acquisition of the donor, along with affordability and provision of immunotherapy in post-transplantation period. Historically, haplo-HCT was associated with compromised outcomes because of high rates of graft-versus-host disease and graft failure, but after the development of a post-transplantation high-dose cyclophosphamide strategy, which results in selective T-cell depletion, these issues have been addressed to a large extent. Read More

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December 2018
1 Read

Global Development of Anticancer Therapies for Rare Cancers, Pediatric Cancers, and Molecular Subtypes of Common Cancers.

J Glob Oncol 2018 Dec(4):1-11

H. Kim Lyerly, Duke University, Durham, NC; Jun Ren, Capital University Medical Center; Zhimin Yang, China Food and Drug Administration, Beijing, People's Republic of China; Gi Hyun Kim, Korea Ministry of Food and Drug Safety, Seoul, South Korea; Sumimasa Nagai, University of Tokyo; Sumimasa Nagai, Tomohiro Yamaguchi, and Ken Hatogai, Pharmaceuticals and Medical Devices Agency; Hiroshi Katayama, National Cancer Center Hospital, Tokyo, Japan; Silvy Da Rocha Dias, European Medicines Agency, London, United Kingdom; Daniel McManus and Kathy Soltys, Health Canada, Ottawa, Ontario, Canada; Olufumilayo Olopade, University of Chicago, Chicago, IL; Nancy Goodman, Kids V Cancer, Washington, DC; Greg Reaman, US Food and Drug Administration; Thomas Gross, US National Cancer Institute, Bethesda, MD, and Renzo Canetta, Independent Consultant.

Advances in genetic sequencing and other diagnostic technologies have enabled the use of precision medicine in clinical cancer care, as well as the development of novel therapies that are targeted to specific molecular drivers of cancer. Developing these new agents and making them accessible to patients requires global clinical studies and regulatory review and approval by different national regulatory agencies. Whereas these global trials present challenges for drug developers who conduct them and regulatory agencies who oversee them, they also raise practical issues about patients with low-frequency cancers who need these therapies. Read More

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December 2018
1 Read

Obstetric Racism: The Racial Politics of Pregnancy, Labor, and Birthing.

Authors:
Dána-Ain Davis

Med Anthropol 2018 Dec 6:1-14. Epub 2018 Dec 6.

a Center for the Study of Women and Society, Graduate Center , City University of New York , New York , USA.

In this article, I analyze the birth stories of Black women living in the United States. Their birth stories describe various forms of racism during medical encounters while they were pregnant or during labor and delivery. In the global women's health arena, the issues raised are viewed as obstetric violence. Read More

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December 2018

Phosphorene as a Catalyst for Highly Efficient Nonaqueous Li-Air Batteries.

ACS Appl Mater Interfaces 2018 Dec 6. Epub 2018 Dec 6.

Li-Air batteries can yield exceptionally high predicted energy densities. However, for this technology to become realizable, round trip efficiency issues and slow kinetics at the cathode require implementation of a catalyst. With design parameters not well understood, and limitations on material selection, choosing an ideal catalyst is complex. Read More

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December 2018

PPICurator: a tool for extracting comprehensive protein-protein interaction information.

Proteomics 2018 Dec 6:e1800291. Epub 2018 Dec 6.

State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Life Omics, Beijing, 102206, P. R. China.

PPI extraction through biological literature curation has been widely employed for proteome analysis. There is a strong need for a tool that can assist researchers in extracting comprehensive PPI information through literature curation, which is critical in research on protein, e.g. Read More

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December 2018
3 Reads

High-Value Interviewing: A Call for Quality Improvement in the Match Process.

Acad Med 2018 Dec 4. Epub 2018 Dec 4.

B. Frush is a first-year resident in internal medicine-pediatrics, Vanderbilt University Medical Center and Monroe Carell Jr Children's Hospital at Vanderbilt, Nashville, Tennessee. The author was a fourth-year medical student, University of North Carolina School of Medicine, Chapel Hill, North Carolina, at the time of writing. J. Byerley is professor of pediatrics, vice dean for education, and chief education officer, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

Within the Match process, current residency interview practices are inefficient for both applicants and programs. Problems include disorganized interview offers and scheduling, excessive numbers of applicant interviews, unclear postinterview communication policies, and the significant expenses entailed. To address these issues, the authors propose applying a quality improvement approach to create a high-value interview process that would decrease investments of time, money, and energy and improve the quality of the Match experience for both applicants and programs. Read More

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December 2018

Psychosis in neurodegenerative disorders: recent developments.

Curr Opin Psychiatry 2018 Dec 5. Epub 2018 Dec 5.

Keenan Research Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital.

Purpose Of Review: This review presents the latest developments covered in the literature regarding psychosis in neurodegenerative disorders and discusses possible future research directions.

Recent Findings: Recent findings in the field of psychosis and neurodegenerative disorders revolve around four main themes. The first theme is the impact of sex on the expression of psychosis in neurodegenerative disorders. Read More

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December 2018

A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV.

Elife 2018 Dec 6;7. Epub 2018 Dec 6.

Divisions of Human Biology and Basic Sciences, Fred Hutchinson Cancer Research Center, Washington, United States.

Interferon (IFN) inhibits HIV replication by inducing antiviral effectors. To comprehensively identify IFN-induced HIV restriction factors, we assembled a CRISPR sgRNA library of Interferon Stimulated Genes (ISGs) into a modified lentiviral vector that allows for packaging of sgRNA-encoding genomes into budding HIV-1 particles. We observed that knockout of Zinc Antiviral Protein (ZAP) improved the performance of the screen due to ZAP-mediated inhibition of the vector. Read More

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December 2018

Treatment-resistant and multi-therapy-resistant criteria for bipolar depression: consensus definition.

Br J Psychiatry 2018 Dec 6:1-9. Epub 2018 Dec 6.

Clinical Senior Lecturer in Mood Disorders and Consultant Psychiatrist,National Affective Disorders Service; Academic Psychiatry Training Programme Lead,Institute of Psychiatry,Psychology and Neuroscience,King's College London,South London and Maudsley NHS Foundation Trust (SLaM); andCRN South London Lead for Mental Health,Centre for Affective Disorders, Institute of Psychiatry,Psychology and Neuroscience,King's College London,South London and Maudsley NHS Foundation Trust (SLaM),UK.

Background: Most people with bipolar disorder spend a significant percentage of their lifetime experiencing either subsyndromal depressive symptoms or major depressive episodes, which contribute greatly to the high levels of disability and mortality associated with the disorder. Despite the importance of bipolar depression, there are only a small number of recognised treatment options available. Consecutive treatment failures can quickly exhaust these options leading to treatment-resistant bipolar depression (TRBD). Read More

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December 2018
4 Reads

Target discovery for new antitubercular drugs using a large dataset of growth inhibitors from PubChem.

Authors:
Robert C Goldman

Infect Disord Drug Targets 2018 Dec 5. Epub 2018 Dec 5.

Drug Discovery and Development, RCG Consulting, 16024 Golden Lakes Drive. United States.

The number of drugs available for treatment of active tuberculosis are diminishing due to increased multidrug resistance selection in Mycobacterium tuberculosis leading to multiple (MDR) and extensively (XDR) resistant strains. Also, TB is treated with multiple drugs to minimize further resistance development, mandating a sustained effort to identify new lead compounds for treating drug resistant TB, and shortening time to cure for all TB infections. High throughput screening, a well-known approach to discovery of new leads, is conducted in two basic modes 1) using whole cells and screening for inhibition of growth, or whole cell reporter cells that signals when a specific pathway is perturbed, and 2) in vitro non-cell based enzyme or other functional assays for direct ligand-target binding. Read More

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December 2018

Neural correlates of the effect of implementation intention on prospective memory.

Psych J 2018 Dec 5. Epub 2018 Dec 5.

Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China.

Prospective memory (PM) refers to the ability to remember to do something in the future. Implementation intention refers to a self-regulatory strategy in the form of "If …, then …" planning that can improve PM performance. However, the neural basis of the effect of implementation intention on PM remains unclear, as do the phases of PM that are affected by implementation intention. Read More

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December 2018
2 Reads

Transition to practice experiences of first and second career nurses: A mixed methods study.

J Clin Nurs 2018 Dec 5. Epub 2018 Dec 5.

School of Nursing, University of Wisconsin Madison, Madison, WI, United States.

Aims And Objectives: To explore the transition to nursing practice experiences of first and second career nursing students.

Background: To address the nursing shortage, alternative educational programs have been increasingly developed and implemented with to help individuals with prior career experiences transition into a career in nursing (second career nurses). However, we know little about the transition to practice experiences of second career nurses. Read More

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December 2018
1 Read

Abortion by telemedicine in the European Union.

Int J Gynaecol Obstet 2018 Dec 5. Epub 2018 Dec 5.

Kent Law School, University of Kent, Canterbury, UK.

This paper analyses an important set of legal issues raised by the telemedical provision of abortion pills. Focusing on the case of European Union (EU) law, it suggests that a properly accredited doctor seeking to treat a patient with abortion pills is entitled, in principle, to rely on EU rules of free movement to protect their access to patients in other member states, and women facing unwanted pregnancies likewise have legal rights to access the services thus offered. EU countries seeking to claim an exception to those rules on the basis of public health or the protection of a fundamental public policy interest (here, the protection of fetal life) will face significant barriers. Read More

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December 2018
2 Reads

What Is the Good of It-Ethical Controls of Human Subject Health Research? : Curtin University Annual Ethics Lecture.

Authors:
Robert French

J Bioeth Inq 2018 Dec 5. Epub 2018 Dec 5.

Chancellery, M460A, The University of Western Australia, 35 Stirling Highway, Perth, WA, 6009, Australia.

The term "ethics" covers a multitude of virtues and possibly some sins where ethical perspectives differ. Given the diversity of ethical philosophies there is a question about what common ground can, or should, inform health research ethics. At a minimum it must be consistent with the law. Read More

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December 2018

Opioid Use is Associated with Higher Severity-Adjusted Episode Costs in Patients with Conservatively Managed Degenerative Joint Disease of the Back and Neck.

Pharmacoeconomics 2018 Dec 6. Epub 2018 Dec 6.

Clinical Data Services and Analytics, UnitedHealthcare, 9700 Health Care Lane, Minnetonka, MN, 55343, USA.

Background: Opioid use and misuse are urgent health issues. Previous studies suggest that opioid use increases healthcare resource use but severity adjustment is lacking.

Objective: The objective of this study was to evaluate the severity-adjusted cost difference between opioid users and non-users among patients with conservatively managed degenerative joint disease of the spine within a large commercial health plan population in the United States. Read More

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December 2018
1 Read

Organochlorine pesticides exposure in female adolescents: potential impact on sexual hormones and interleukin-1 levels.

Immunol Res 2018 Dec 6. Epub 2018 Dec 6.

Department of Obstetrics and Gynecology, National Research Center of Mother and Child Health, University Medical Center, 32 Turan Avenue, Astana, 010000, Kazakhstan.

The objective of this study was to assess the potential impact of organochlorine pesticides (OCPs) on IL-1 axis in exposed female adolescents through an observational cross-sectional study. The study was conducted in Sary-Agach District (OCPs exposed girls) and Sairam District (OCPs unexposed controls), South Kazakhstan. The study included 524 female adolescents aged 10-17 years (OCPs exposed, n = 253; OCPs unexposed, n = 271). Read More

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December 2018
1 Read

Needs-focused interventions for family caregivers of older adults with cancer: a descriptive interpretive study.

Support Care Cancer 2018 Dec 5. Epub 2018 Dec 5.

Faculty of Medicine and Health Sciences, Université de Sherbrooke, Longueuil, QC, Canada.

Purpose: Although family caregivers (FCs) of older adults with cancer (OACs) provide invaluable assistance by fulfilling multiple tasks along the cancer trajectory, evidence suggests that their needs are poorly assessed, and there is a scarcity of supportive interventions that influence their well-being. Viewing these issues as opportunities for improvement, we conducted this qualitative study to understand FCs' needs and identify promising needs-focused interventions.

Methods: This descriptive interpretive qualitative study was conducted in Quebec, Canada, in a French Canadian Oncology Clinic. Read More

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December 2018

Influenza vaccination discourse in major Canadian news media, 2017-2018.

Heliyon 2018 Nov 27;4(11):e00970. Epub 2018 Nov 27.

Health Law Institute, University of Alberta Faculty of Law, Edmonton, Alberta, Canada.

Influenza vaccine uptake is less-than-ideal in many jurisdictions, including Canada. In this study we sought to assess news articles relating to influenza vaccination by major Canadian newspapers during a six-month period relatively congruent to the seasonal influenza outbreak for 2017-2018. We identified 116 unique articles published between August 16, 2017 and February 15, 2018, then developed and applied a coding frame to them. Read More

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November 2018

RNA Sequencing Reveals the Suitability of Cardiac Death Livers for Transplantation.

Biomed Res Int 2018 1;2018:8217486. Epub 2018 Nov 1.

Institute of Liver Transplantation, General Hospital of Chinese People's Armed Police Force, Beijing, China.

Background: Organ transplantation is considered the best treatment for end-stage organ failure. However, the lack of available organs for transplantation and the increasing number of patients waiting for transplants are primary issues facing the transplant community. Thus, developing strategies to increase the number of donors, especially for liver transplantation, has become a priority. Read More

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November 2018

Evaluating the Longitudinal Item and Category Stability of the SF-36 Full and Summary Scales Using Rasch Analysis.

Biomed Res Int 2018 4;2018:1013453. Epub 2018 Nov 4.

The University of Newcastle, School of Medicine and Public Health, Callaghan, New South Wales, Australia.

Introduction: The Medical Outcome Study Short Form 36 (SF-36) is widely used for measuring Health-Related Quality of Life (HRQoL) and has undergone rigorous psychometric evaluation using Classic Test Theory (CTT). However, Item Response Theory-based evaluation of the SF-36 has been limited with an overwhelming focus on individual scales and cross-sectional data.

Purpose: This study aimed to examine the longitudinal item and category stability of the SF-36 using Rasch analysis. Read More

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November 2018

Participatory Action Research: Tools for Disaster Resilience Education.

Int J Disaster Resil Built Environ 2018 ;9(4-5):402-419

Department of Landscape Architecture and Urban Planning, Texas A&M University, College Station, TX.

Purpose: Participatory action research can improve scientific knowledge and community capacity to address disaster resilience and environmental justice. Evidence from the literature suggests that resident participation enhances assessment of environmental risks, raises awareness, and empowers residents to fight for equitable distribution of hazard and climate risk adaptations. Yet, risk assessment and urban planning processes still frequently operate within expertise-driven groups without significant community engagement. Read More

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January 2018

Telemental Health in Low- and Middle-Income Countries: A Systematic Review.

Int J Telemed Appl 2018 1;2018:9602821. Epub 2018 Nov 1.

Department of Clinical Medicine, Faculty of Health Sciences, The Arctic University of Norway (UiT), N-9037 Tromsø, Norway.

Introduction: The rising incidence of mental illness and its impact on individuals, families, and societies is becoming a major public health concern, especially in resource-constrained countries. Consequently, there is an increasing demand for mental health services in many middle- and low-income countries (LMIC). Challenges such as inequality in access, lack of staff and hospital beds, and underfunding, often present in the LMIC, might in part be addressed by telemental health services. Read More

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November 2018

Nursing in an age of multimorbidity.

BMC Nurs 2018 29;17:49. Epub 2018 Nov 29.

4School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.

Background: A changing sociodemographic landscape has seen rising numbers of people with two or more long-term health conditions. Multimorbidity presents numerous challenges for patients and families and those who work in healthcare services. Therefore, the nursing profession needs to understand the issues involved in supporting people with multiple chronic conditions and how to prepare the future workforce to care for them. Read More

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November 2018

Metabolic aspects in NAFLD, NASH and hepatocellular carcinoma: the role of PGC1 coactivators.

Nat Rev Gastroenterol Hepatol 2018 Dec 5. Epub 2018 Dec 5.

Department of Interdisciplinary Medicine, Aldo Moro University of Bari, Bari, Italy.

Alterations of hepatic metabolism are critical to the development of liver disease. The peroxisome proliferator-activated receptor-γ coactivators (PGC1s) are able to orchestrate, on a transcriptional level, different aspects of liver metabolism, such as mitochondrial oxidative phosphorylation, gluconeogenesis and fatty acid synthesis. As modifications affecting both mitochondrial and lipid metabolism contribute to the initiation and/or progression of liver steatosis, nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC), a link between disrupted PGC1 pathways and onset of these pathological conditions has been postulated. Read More

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December 2018
1 Read

Association between brown adipose tissue and bone mineral density in humans.

Int J Obes (Lond) 2018 Dec 5. Epub 2018 Dec 5.

PROFITH "PROmoting FITness and Health through physical activity" research group, Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Ctra. de Alfacar s/n, C.P., 18071, Granada, Spain.

Background: Brown adipose tissue (BAT) seems to play a role in bone morphogenesis. A negative association has been reported between BAT and bone mineral density (BMD) in women, but not in men. A panel of experts has recently published a set of recommendations for BAT assessment, and thus, to re-address previously reported associations is needed. Read More

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December 2018
1 Read

Investigation into Lipid Management in Acute Coronary Syndrome Patients from the EXPLORE-J Study.

J Atheroscler Thromb 2018 Dec 4. Epub 2018 Dec 4.

Department of Molecular Innovation in Lipidology, National Cerebral & Cardiovascular Center Research Institute.

Aims: The EXPLORE-J study aimed to assess lipid management in patients hospitalized for acute coronary syndrome (ACS) and their cardiovascular risk despite undergoing standard therapy. Here, we focused on background characteristics of patients in the EXPLORE-J study to elucidate the current lipid-lowering therapy and its issues in Japan.

Methods: In this multicenter, prospective, observational study (UMIN000018946), consecutive Japanese ACS patients who required hospitalization were registered between April 2015 and August 2016. Read More

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December 2018
1 Read

Associations between neurochemical receptor genes, 2D:4D, impulsivity and relationship quality.

Biol Lett 2018 Dec 5;14(12). Epub 2018 Dec 5.

Social and Evolutionary Neuroscience Research Group, Department of Experimental Psychology, University of Oxford, Anna Watts Building, Radcliffe Observatory, Woodstock Road, Quarter, Oxford OX2 6GG, UK.

The ratio between the second and fourth digits (2D:4D) has been widely used as a proxy for fetal exposure to androgens and has been linked to a number of sociosexual traits in humans. However, the role of genes in this equation remains unknown. Here ( = 474), we test, firstly, for associations between 2D:4D and single-nucleotide polymorphisms (SNPs) in nine neurochemical receptor genes (), and secondly, whether digit ratios mediate the relationship between genetic variation and sociosexuality. Read More

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December 2018

Mining and biodiversity: key issues and research needs in conservation science.

Proc Biol Sci 2018 Dec 5;285(1892). Epub 2018 Dec 5.

Centre for Biodiversity and Conservation Science, The University of Queensland, Queensland 4072, Australia.

Mining poses serious and highly specific threats to biodiversity. However, mining can also be a means for financing alternative livelihood paths that, over the long-term, may prevent biodiversity loss. Complex and controversial issues associated with mining and biodiversity conservation are often simplified within a narrow frame oriented towards the negative impacts of mining at the site of extraction, rather than posed as a series of challenges for the conservation science community to embrace. Read More

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December 2018

Polycystosis of the renal sinus or polycystic kidney disease Controversies, challenges and history of a shared discovery.

Actas Urol Esp 2018 Dec 6;42(10):645-648. Epub 2018 Jul 6.

Servicio de Urología, Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Madrid, España.

Objective: To recall the history of the discovery of non-nephron cystic disease, detected simultaneously in 2 hospitals in Madrid, and the vicissitudes that the authors endured during the process of recognising this disease, while being ignored by the international scientific literature.

Material And Method: We analysed the authors' first publications and presentations, their correspondence relaying the difficulties in reporting the confusion with adult polycystic kidney disease (APKD) and the subsequent nosological identification of the process. We consulted with individuals who worked with the 2 authors to increase the accuracy and objectivity of the history report. Read More

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December 2018

Determinants of the willingness to participate in biobanking among Malaysian stakeholders in the Klang Valley.

BMC Med Res Methodol 2018 Dec 5;18(1):163. Epub 2018 Dec 5.

Pusat Citra Universiti, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia.

Background: The demand in biobanking for the collection and maintenance of biological specimens and personal data from civilians to improve the prevention, diagnosis and treatment of diseases has increased notably. Despite the advancement, certain issues, specifically those related to privacy and data protection, have been critically discussed. The purposes of this study are to assess the willingness of stakeholders to participate in biobanking and to determine its predictors. Read More

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December 2018

The experience of gestational diabetes for indigenous Māori women living in rural New Zealand: qualitative research informing the development of decolonising interventions.

BMC Pregnancy Childbirth 2018 Dec 5;18(1):478. Epub 2018 Dec 5.

c/- Te Kupenga Hauora Māori, Medical and Health Sciences, University of Auckland, 261 Morrin Rd, Glen Innes, Auckland, 1072, New Zealand.

Background: Although early detection and management of excess rates of gestational diabetes mellitus (GDM) among Indigenous women can substantially reduce maternal and offspring complications, current interventions seem ineffective for Indigenous women. While undertaking a qualitative study in a rural community in Northland, New Zealand about the complexities of living with diabetes, we observed a common emotional discourse about the burden of diabetic pregnancies. Given the significance of GDM and our commitment to give voice to Indigenous Māori women in ways that could potentially inform solutions, we aimed to explore the phenomenon of GDM among Māori women in a rural context marked by high area-deprivation. Read More

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December 2018

Self-silencing and women's health: A review.

Int J Soc Psychiatry 2018 Dec 5:20764018814271. Epub 2018 Dec 5.

Department of Humanities and Social Sciences, Indian Institute of Technology Kanpur, Kanpur, India.

The connection between gender and health has intrigued health professionals in the last few decades. Silencing-the-self theory has brought a considerable clarity in this matter. After around three decades of the theory, the literature related to the theory has immensely flourished and has covered different branches of psychology. Read More

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December 2018
4 Reads

Cu-substituted NiF2 as Cathode Material for Li-ion Batteries.

ACS Appl Mater Interfaces 2018 Dec 6. Epub 2018 Dec 6.

Metal fluorides have usually a large electronegativity and are promising electrode materials for high power lithium-ion batteries. However, like other conversion reaction based materials, large volumetric expansions and large capacity losses in cycling are major issues for metal fluorides. Here, we explore substitution of Ni with Cu for binary NiF2 and its effects to the electrochemical properties. Read More

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December 2018
1 Read

Microfluidic Deformability Study of an Innovative Blood Analogue Fluid Based on Giant Unilamellar Vesicles.

J Funct Biomater 2018 Dec 4;9(4). Epub 2018 Dec 4.

MEtRICs, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal.

Blood analogues have long been a topic of interest in biofluid mechanics due to the safety and ethical issues involved in the collection and handling of blood samples. Although the current blood analogue fluids can adequately mimic the rheological properties of blood from a macroscopic point of view, at the microscopic level blood analogues need further development and improvement. In this work, an innovative blood analogue containing giant unilamellar vesicles (GUVs) was developed to mimic the flow behavior of red blood cells (RBCs). Read More

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December 2018
2 Reads

Clinical Trials and Administration of Zika Virus Vaccine in Pregnant Women: Lessons (that Should Have Been) Learned from Excluding Immunization with the Ebola Vaccine during Pregnancy and Lactation.

Authors:
David A Schwartz

Vaccines (Basel) 2018 Dec 4;6(4). Epub 2018 Dec 4.

Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.

As evidenced from recent epidemics, both Ebola and Zika virus infection are potentially catastrophic when occurring in pregnant women. Ebola virus causes extremely high rates of mortality in both mothers and infants; Zika virus is a TORCH infection that produces a congenital malformation syndrome and pediatric neurodevelopmental abnormalities. Production of efficacious vaccines has been a public health priority for both infections. Read More

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December 2018

L’EBM étouffe de ses excès sans qu’on ait obtenu la preuve de ses bénéfices.

Rev Prat 2016 Nov;67(9):1010-1012

Professeur honoraire de la faculté de médecine de Lille, Lille, France.

Evidence-based medicine criticism. Evidence-based medicine is now considered as the rule in the practice of clinical medicine. It covers however a lot of issues and limitations, leading to numerous and severe pitfalls. Read More

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November 2016

Experience Doesn't Reduce All Stress: An Exploration of Perceived Stress Among Graduate Students in Speech-Language Pathology.

J Allied Health 2018 ;47(4):277-281

Department of Communication Sciences and Disorders, Communication Equity and Outcomes Laboratory, East Carolina University, 3310H Health Sciences Bldg., MS 668, Greenville, NC 27834, USA. Tel 252-744-6098, fax 252-744-6109.

Aims: Stress is a common issue among students enrolled in graduate programs. Evidence suggests the specific factors driving and associated with stress may be unique to the characteristics of individual programs. The purpose of this study was to examine perceived stress among first- and second-year graduate students in a speech-language pathology (SLP) master's program. Read More

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January 2018

Clinical Experiences: Navigating the Intricacies of Student Placement Requirements.

J Allied Health 2018 ;47(4):237-242

Dep. of Clinical Laboratory Sciences, The University of Tennessee Health Science Center, 930 Madison Ave, Suite 662, Memphis, TN 38163, USA. Tel 901-448-2136, fax 901-448-7545.

Clinical apprenticeships, also called clinical experiences, are integral to most allied health (AH) student professional education. Clinical experiences begin the process of enculturating students into a healthcare profession where higher cognitive mastery of learned skills is supported through social interaction and scaffolding with an AH professional. In AH programs, clinical experiences for students are a necessity for programmatic accreditation; however, clinical sites have developed a range of requirements for students, which lead to a myriad of issues. Read More

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January 2018

Recognizing and Managing Snapping Hip Syndrome in Dancers.

Med Probl Perform Art 2018 Dec;33(4):286-291

George Mason University, 10890 George Mason Circle, Manassas, VA 20110 USA. Tel 703-993-2123, fax 703-993-2060.

Background: Snapping hip syndrome (SHS) is a common hip pathology in dancers. SHS can be either internal or external, resulting from muscle tendon tightness from repetitive hip flexion and extension, accompanied with hip abduction and/or external rotation. Muscular tightness may cause the tendon to become taut and snap over a bony prominence during hip movement, leading to muscular weakness and reduced range of motion from pain. Read More

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December 2018

Endocardial transvenous pacing in patients with surgically palliated univentricular hearts: A review on different techniques, problems and management.

Indian Pacing Electrophysiol J 2018 Nov 30. Epub 2018 Nov 30.

Department of Pediatric Cardiology, Madras Medical Mission, Chennai, India. Electronic address:

Fontan surgery and its modifications have improved survival in various forms of univentricular hearts. A regular atrial rhythm with atrioventricular synchrony is one of the most important prerequisite for the long-term effective functioning of this preload dependent circulation. A significant proportion of these survivors need various forms of pacing for bradyarrhythmias, often due to sinus nodal dysfunction and sometimes due to atrioventricular nodal block. Read More

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November 2018