10,971 results match your criteria Irish Journal of Medical Science [Journal]


Point of Care Echocardiography in an Irish Critical Care Unit

Ir Med J 2018 09 10;111(8):800. Epub 2018 Sep 10.

Consultant Intensivist, Mater Misercordiae University Hospital, Eccles Street, Dublin 7, Ireland

Aims We sought to evaluate the clinical impact of a 6 month transthoracic echocardiography (TTE) teaching programme in a critical care unit. Methods An observational single centre study. Four critical care doctors, 2 fellows and 2 consultants were trained to use TTE. Read More

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September 2018
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Irish general practitioners' view of perinatal mental health in general practice: a qualitative study.

BMC Fam Pract 2018 Dec 13;19(1):196. Epub 2018 Dec 13.

School of Allied Health, Faculty of Education & Health Sciences, Health Sciences Building, University of Limerick, Limerick, Ireland.

Background: Identification of perinatal mental health problems and effective care for women who experience them are important considering the potentially serious impact that they may have on the wellbeing of the woman, her baby, family and wider society. General practitioners (GPs) play a central role in identifying and supporting women and this study aimed to explore GPs' experiences of caring for women with perinatal mental health problems in primary care. The results of this study may provide guidance to inform policy, practice, research and development of curriculum and continuous professional development resources. Read More

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December 2018

Audiovisual infotainment in European news: A comparative content analysis of Dutch, Spanish, and Irish television news programs.

Journalism (Lond) 2018 Nov 5;19(11):1534-1551. Epub 2016 Oct 5.

University of Amsterdam, The Netherlands.

This study investigates to what extent audiovisual infotainment features can be found in the narrative structure of television news in three European countries. Content analysis included a sample of 639 news reports aired in the first 3 weeks of September 2013, in six prime-time TV news broadcasts of Ireland, Spain, and the Netherlands. It was found that Spain and Ireland included more technical features of infotainment in television news compared to the Netherlands. Read More

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November 2018

Variation in outcome reporting in randomised controlled trials of interventions for the prevention and treatment of fetal growth restriction.

Ultrasound Obstet Gynecol 2018 Dec 6. Epub 2018 Dec 6.

Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, UK.

Background: Fetal growth restriction (FGR) contributes to stillbirth, prematurity, neonatal and infant mortality and morbidity. Although FGR is well known to be associated with adverse outcomes for the mother and offspring, effective interventions for the prevention of FGR are yet to be established. The majority of pregnancies complicated by FGR are not detected antenatally and there are limited effective interventions for established FGR. Read More

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December 2018

It's All About the Brain-Neuromonitoring During Newborn Transition.

Semin Pediatr Neurol 2018 Dec 22;28:48-59. Epub 2018 Nov 22.

Department of Paediatrics and Child Health, Neonatal Intensive Care Unit, University College Cork, Cork, Ireland; INFANT, Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland. Electronic address:

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December 2018

Cross-language differences in how voice quality and contours map to affect.

J Acoust Soc Am 2018 Nov;144(5):2730

Phonetics and Speech Laboratory, School of Linguistic, Speech and Communication Sciences, Trinity College Dublin, Dublin, Ireland.

The relationship between prosody and perceived affect involves multiple variables. This paper explores the interplay of three: voice quality, contour, and the hearer's language background. Perception tests were conducted with speakers of Irish English, Russian, Spanish, and Japanese using three types of synthetic stimuli: (1) stimuli varied in voice quality, (2) stimuli of uniform (modal) voice quality incorporating affect-related contours, and (3) stimuli combining specific non-modal voice qualities with the affect-related contours of (2). Read More

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November 2018

Burden of disease (BoD), disability-adjusted life years (DALY) and frailty prevalence.

QJM 2018 Dec 12. Epub 2018 Dec 12.

Clinical Sciences Institute, National University of Ireland, Galway (NUIG), Galway City, Ireland.

Background: Burden of disease (BoD) using disability-adjusted life years (DALY) is a useful summary measure of population health and estimates are provided for Ireland annually. We hypothesised that BoD may be used as a predictor of frailty prevalence.

Aim: To examine the correlation between frailty measured by the accumulation of deficits (frailty index, FI) and Fried Frailty Phenotype (FFP) classifications and BoD, in an Irish context. Read More

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December 2018
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The Functions of Prospection - Variations in Health and Disease.

Front Psychol 2018 27;9:2328. Epub 2018 Nov 27.

The University of Sydney, Brain and Mind Centre, School of Psychology, Sydney, NSW, Australia.

Much of human life revolves around anticipating and planning for the future. It has become increasingly clear that this capacity for is a core adaptive function of the mind. Here, we review the role of prospection in two key functional domains: goal-directed behavior and flexible decision-making. Read More

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November 2018

Barriers and facilitators to hepatitis C (HCV) screening and treatment-a description of prisoners' perspective.

Harm Reduct J 2018 Dec 11;15(1):62. Epub 2018 Dec 11.

School of Medicine University College, Dublin, Ireland.

Background: Hepatitis C virus (HCV) infection is a global epidemic with an estimated 71 million people infected worldwide. People who inject drugs (PWID) are overrepresented in prison populations globally and have higher levels of HCV infection than the general population. Despite increased access to primary health care while in prison, many HCV infected prisoners do not engage with screening or treatment. Read More

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December 2018

Novel strains in malaria vectors from Sub-Saharan Africa.

Wellcome Open Res 2018 27;3:113. Epub 2018 Nov 27.

Department of Disease Control, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.

, a common insect endosymbiotic bacterium that can influence pathogen transmission and manipulate host reproduction, has historically been considered absent from the  genera, but has recently been found in  s.l. populations in West Africa. Read More

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November 2018
2 Reads

The relationship between oral-health-related quality of life and general health in an elderly population: A cross-sectional study.

Gerodontology 2018 Dec 7. Epub 2018 Dec 7.

Epidemiology and Public Health, University College Cork, Cork, Ireland.

Objective: To assess the oral-health-related quality of life (OHRQoL) in a cohort of Irish older patients and explore associations with overall health status.

Background: The impact of oral health conditions on older individuals' quality of life may be influenced by patients' general health status.

Materials And Methods: This paper reports a cross-sectional study, which analysed baseline data from patients aged over 60 years. Read More

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December 2018

Safe adoption of robotic colorectal surgery using structured training: early Irish experience.

J Robot Surg 2018 Dec 10. Epub 2018 Dec 10.

Beacon Hospital, Beacon Court, Sandyford, Dublin 18, Republic of Ireland.

Robotic surgery enhances the precision of minimally invasive surgery through improved three-dimensional views and articulated instruments. There has been increasing interest in adopting this technology to colorectal surgery and this has recently been introduced to the Irish health system. This paper gives an account of our early institutional experience with adoption of robotic colorectal surgery using structured training. Read More

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December 2018
3 Reads

Integrating self-management into daily life following primary treatment: head and neck cancer survivors' perspectives.

J Cancer Surviv 2018 Dec 8. Epub 2018 Dec 8.

School of Nursing and Human Sciences, Dublin City University, Dublin, Ireland.

Background: Self-management may help cancer survivors to better deal with challenges to their physical, functional, social and psychological well-being presented by cancer and its treatment. Nonetheless, little is known about how people integrate cancer self-management practices into their daily lives. The aim of this study was to describe and characterise the processes through which head and neck cancer (HNC) survivors attempt to integrate self-management into their daily lives following primary treatment. Read More

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December 2018
1 Read

The bovine tuberculosis cluster in north County Sligo during 2014-16.

Ir Vet J 2018 28;71:24. Epub 2018 Nov 28.

2Centre for Veterinary Epidemiology and Risk Analysis, UCD School of Veterinary Medicine, University College Dublin, Belfield, Dublin, D04 W6F6 Ireland.

Background: Bovine tuberculosis (bTB, caused by infection with ) is endemic in the Irish cattle population, and the subject of a national eradication programme since the late 1950s. During 2014, a substantial area-level bTB outbreak developing in north County Sligo, necessitating the need for an enhanced response. This paper describes this outbreak, the response that was undertaken and some lessons learned. Read More

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November 2018

A comparison of helminth infections as assessed through coprological analysis and adult worm burdens in a wild host.

Int J Parasitol Parasites Wildl 2018 Dec 14;7(3):439-444. Epub 2018 Nov 14.

Department of Zoology, School of Natural Sciences, Trinity College Dublin, Ireland.

Coprological analysis is the most widely used diagnostic tool for helminth infection in both domestic and wild mammals. Evaluation of the efficacy of this technique is rare, due to the lack of availability of adult worm burden. Where information is available the majority of studies are in small ruminants and seldom in a wild host. Read More

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December 2018

Acute Exercise Effects among Young Adults with Analog Generalized Anxiety Disorder.

Med Sci Sports Exerc 2018 Dec 5. Epub 2018 Dec 5.

Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland.

Recent findings support positive effects of acute aerobic exercise on worry, state anxiety, and feelings of energy and fatigue among young adult women with subclinical, or analogue, Generalized Anxiety Disorder (GAD). However, exercise effects among young adult men with analogue GAD are unstudied.

Purpose: This study replicated initial findings of positive effects of acute vigorous-intensity aerobic exercise on worry, state anxiety, and feelings of energy and fatigue among young adult women with analogue GAD, examined responses among young adult men with analogue GAD, and explored sex-related differences and moderation by physical activity level, trait anxiety, depression, and poor sleep status. Read More

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December 2018
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Metabolomics for predicting fetal growth restriction: protocol for a systematic review and meta-analysis.

BMJ Open 2018 Dec 6;8(12):e022743. Epub 2018 Dec 6.

Department of Gynaecology and Obstetrics, University Campinas, Sao Paulo, Brazil.

Introduction: Fetal growth restriction (FGR) is a relevant research and clinical concern since it is related to higher risks of adverse outcomes at any period of life. Current predictive tools in pregnancy (clinical factors, ultrasound scan, placenta-related biomarkers) fail to identify the true growth-restricted fetus. However, technologies based on metabolomics have generated interesting findings and seem promising. Read More

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December 2018

The impact of stress latent class membership and transitions on statutory service and alcohol use in adolescents across 33 months.

J Adolesc 2018 Dec 5;70:53-61. Epub 2018 Dec 5.

University of Liverpool, United Kingdom. Electronic address:

Introduction: Adolescence is a period of intense physical, biological, and psychological change, and this can result in feelings of stress. We examined the development of stress in early adolescence, and further, how that development impacted on both alcohol-use behaviours and utilisation of government-provided services.

Methods: We used a shortened, 24-item version of the Adolescent Stress Questionnaire (ASQ) to account for stress, and applied latent transition analysis to examine longitudinal change. Read More

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December 2018

Prospective biomarkers in preterm preeclampsia: A review.

Pregnancy Hypertens 2018 Oct 23;14:72-78. Epub 2018 Mar 23.

NIHR Research Professor in Obstetrics, King's College London. Honorary Consultant Obstetrician, St Thomas' Hospital, London SE1 7EH, UK.

Preterm pre-eclampsia (prior to 37 weeks' gestation) remains a major cause of maternal and fetal morbidity and mortality particularly in low to middle income countries. Much research has focused on first and second trimester predictors of pre-eclampsia with the aim of allowing stratification of antenatal care and trialling of potential preventative and therapeutic agents. However, none have been shown to be of benefit in randomised controlled trials. Read More

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October 2018

Defining electronic-prescribing and infusion-related medication errors in paediatric intensive care - a Delphi study.

BMC Med Inform Decis Mak 2018 Dec 7;18(1):130. Epub 2018 Dec 7.

Our Lady's Children's Hospital, Crumlin, Dublin, 12, Ireland.

Background: The use of health information technology (HIT) to improve patient safety is widely advocated by governmental and safety agencies. Electronic-prescribing and smart-pump technology are examples of HIT medication error reduction strategies. The introduction of new errors on HIT implementation is, however, also recognised. Read More

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December 2018

Assessment of ERBB2/HER2 Status in HER2-Equivocal Breast Cancers by FISH and 2013/2014 ASCO-CAP Guidelines.

JAMA Oncol 2018 Dec 6. Epub 2018 Dec 6.

Department of Medicine, Geffen School of Medicine at University of California Los Angeles, Los Angeles.

Importance: The 2013/2014 American Society of Clinical Oncology and College of American Pathologists (ASCO-CAP) guidelines for HER2 testing by fluorescence in situ hybridization (FISH) designated an "equivocal" category (average HER2 copies per tumor cell ≥4-6 with HER2/CEP17 ratio <2.0) to be resolved as negative or positive by assessments with alternative control probes. Approximately 4% to 12% of all invasive breast cancers are characterized as HER2-equivocal based on FISH. Read More

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December 2018
2 Reads

Emergency Department Overcrowding And The Full Capacity Protocol Cross Over Study: What Patients Who Have Experienced Both Think About Being An Extra Patient In The Emergency Department Or On A Ward.

Ir Med J 2018 08 13;111(7):788. Epub 2018 Aug 13.

Emergency Department, Beaumont Hospital, Beaumont Rd, Dublin 9

Hospital overcrowding is evidenced by Emergency Department (ED) overcrowding. The Full Capacity Protocol (FCP) is activated to move patients to temporary extra beds placed in the inpatient wards. This research aims to establish patient preferences when waiting for a ward bed in an Irish Hospital. Read More

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August 2018
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Management of Paediatric Buckle (Torus) Wrist Fractures in Irish Emergency Departments: A National Survey

Ir Med J 2018 08 13;111(7):793. Epub 2018 Aug 13.

Department of Emergency Medicine, University Hospital Galway, Galway

Buckle fractures are the most common wrist fractures reported in the paediatric age group. National Institute for Clinical Excellence (NICE) recommends using a non-rigid immobilisation with no follow up for these patients and appropriate discharge advice. A telephone survey was conducted to assess the variation in practice in Irish hospitals regarding the mpediatrianagement of buckle fractures. Read More

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August 2018
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Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains.

Haemophilia 2018 Dec 6. Epub 2018 Dec 6.

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

Background: The Patient Reported Outcomes, Burdens and Experiences (PROBE) study aims to develop and validate questionnaire for assessing health status in patients with haemophilia and participants without bleeding disorders.

Objective: To investigate the test-retest properties of the PROBE questionnaire.

Methods: The PROBE questionnaire covers four domains and is comprised of 29 questions. Read More

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December 2018

Evolution of the main skeleton-forming genes in sponges (phylum Porifera) with special focus on the marine Haplosclerida (class Demospongiae).

Mol Phylogenet Evol 2018 Nov 28. Epub 2018 Nov 28.

Zoology, School of Natural Sciences and Ryan Institute, National University of Ireland Galway, University Rd., Galway, Ireland. Electronic address:

The skeletons of sponges (Phylum Porifera) are comprised of collagen, often embedded with small siliceous structures (spicules) arranged in various forms to provide strength and flexibility. The main proteins responsible for the formation of the spicules in demosponges are the silicateins, which are related to the cathepsins L of other animals. While the silicatein active site, necessary for the formation of biosilica crystals, is characterized by the amino acids SHN, different variants of the silicatein genes have been found, some that retain SHN at the active site and some that don't. Read More

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November 2018

Medline indexing success and future directions for Irish Journal of Psychological Medicine.

Authors:
John Lyne

Ir J Psychol Med 2018 Dec;35(4):273-274

Royal College of Surgeons in Ireland and North Dublin Mental Health Services,Ashlin Centre,Beaumont Road,Dublin 9,Ireland.

Irish Journal of Psychological Medicine (IJPM) was recently accepted for indexing on Medline. This reflects the high scientific quality of articles published in the journal and highlights the excellent work by publishers, authors, reviewers and the journal editorial board who have contributed to the journal's development over many years. IJPM remains committed to further progression through constant innovation and maintaining the excellent standard of publishing to date. Read More

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December 2018

A national survey of online gambling behaviours.

Authors:
D Columb C O'Gara

Ir J Psychol Med 2018 Dec;35(4):311-319

2Addictions Department,St John of Gods Hospital,Stillorgan,Co Dublin,Ireland; UCD School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.

Objectives: The aim of this study is to look at an Irish population in relation to the online gambling activities people are engaging with, the reasons for gambling online, their attitudes to online gambling and the financial/mental health consequences of online gambling.

Methods: The outline for this study was adapted from a study by McCormack et al. (2014) in relation to online gambling, with the aim of replicating this study in an Irish population. Read More

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December 2018

Malnutrition in older adults: screening and determinants.

Proc Nutr Soc 2018 Dec 3:1-8. Epub 2018 Dec 3.

UCD Institute of Food and Health, University College Dublin,Dublin,Republic of Ireland.

Older adults are at risk of protein-energy malnutrition (PEM). PEM detrimentally impacts on health, cognitive and physical functioning and quality of life. Given these negative health outcomes in the context of an ageing global population, the Healthy Diet for a Healthy Life Joint Programming Initiative Malnutrition in the Elderly (MaNuEL) sought to create a knowledge hub on malnutrition in older adults. Read More

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December 2018

Association of Dynamic Balance With Sports-Related Concussion: A Prospective Cohort Study.

Am J Sports Med 2018 Dec 3:363546518812820. Epub 2018 Dec 3.

Insight Centre for Data Analytics, University College Dublin, Dublin, Ireland.

Background:: Concussion is one of the most common sports-related injuries, with little understood about the modifiable and nonmodifiable risk factors. Researchers have yet to evaluate the association between modifiable sensorimotor function variables and concussive injury.

Purpose:: To investigate the association between dynamic balance performance, a discrete measure of sensorimotor function, and concussive injuries. Read More

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December 2018

Comparison of national cross-sectional breast-feeding surveys by maternal education in Europe (2006-2016).

Public Health Nutr 2018 Dec 5:1-14. Epub 2018 Dec 5.

2Global Nutrition and Health,University College Copenhagen,Sigurdsgade 26, 2200 København N,Denmark.

Objective: Breast-feeding is an important determinant of health of mothers and their offspring. The present study aimed to compare breast-feeding rates across Europe disaggregated by maternal education and establish what proportion achieves at least 50 % exclusive breast-feeding (EBF) at 6 months.Design/SettingSecondary analysis of national or sub-national studies' breast-feeding data for EU Member States plus Norway and Iceland, published in 2006-2016. Read More

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December 2018
3 Reads

Broken Minds and Beaten Bodies: Cultures of Harm and the Management of Mental Illness in Mid- to Late Nineteenth-century English and Irish Prisons.

Soc Hist Med 2018 Nov 15;31(4):688-710. Epub 2018 Jun 15.

Centre for the History of Medicine, Department of History, University of Warwick, Coventry, UK.

This article explores the relationship between the prison and mental illness, focusing on the ways in which the system of separate confinement was associated with mental breakdown and how maintaining the integrity of prison discipline mitigated against prisoners obtaining treatment or removal to an asylum. Examples are taken from English and Irish prisons, from the introduction of separate confinement at Pentonville Prison in London in 1842 until the late nineteenth century, exploring the persistence of the system of separation in the face of evidence that it was harming the minds of prisoners. The article also briefly examines the ways in which prison doctors argued that they were dealing with special categories of prisoner, adept at feigning, intrinsically weak-minded and whose mental deterioration was embedded in their criminality, factors that served to reinforce the harmful environment for mentally ill prisoners. Read More

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November 2018
1 Read

Use of letrozole after aromatase inhibitor-based therapy (NRG Oncology/NSABP B-42): a randomised, double-blind, placebo-controlled phase 3 trial.

Lancet Oncol 2018 Nov 30. Epub 2018 Nov 30.

NRG Oncology/NSABP, Pittsburgh, PA, USA; Allegheny Health Network Cancer Institute, Pittsburgh, PA, USA.

Background: The optimal duration of extended therapy with aromatase inhibitors in patients with postmenopausal breast cancer is unknown. In the NSABP B-42 study, we aimed to determine whether extended letrozole treatment improves disease-free survival after 5 years of aromatase inhibitor-based therapy in women with postmenopausal breast cancer.

Methods: This randomised, double-blind, placebo-controlled, phase 3 trial was done in 158 centres in the USA, Canada, and Ireland. Read More

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November 2018
1 Read

Effects of pathogenic CNVs on physical traits in participants of the UK Biobank.

BMC Genomics 2018 Dec 4;19(1):867. Epub 2018 Dec 4.

MRC Centre for Neuropsychiatric Genetics & Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University, School of Medicine, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.

Background: Copy number variants (CNVs) have been shown to increase risk for physical anomalies, developmental, psychiatric and medical disorders. Some of them have been associated with changes in weight, height, and other physical traits. As most studies have been performed on children and young people, these effects of CNVs in middle-aged and older people are not well established. Read More

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December 2018

Cortical covariance networks in ageing: Cross-sectional data from the Irish Longitudinal Study on Ageing (TILDA).

Neuropsychologia 2018 Nov 27. Epub 2018 Nov 27.

St. James' Hospital, Dublin 8, Ireland; Centre for Advanced Medical Imaging (CAMI), St. James' Hospital, Dublin 8, Ireland.

Ageing is associated with widespread alterations to the brain's anatomy and to attendant cortical networks. Yet, few studies to date have indexed anatomical covariance network differences within the age distribution of older adulthood, despite known phenotypic variation. Here, we explored cortical anatomical covariance networks in middle and older age cross-sectionally, using a large sample of community-dwelling older adults from the Irish Longitudinal Study on Ageing (TILDA). Read More

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November 2018

Seasonal and predator-prey effects on circadian activity of free-ranging mammals revealed by camera traps.

PeerJ 2018 21;6:e5827. Epub 2018 Nov 21.

School of Biological Sciences, Queen's University Belfast, UK.

Endogenous circadian and seasonal activity patterns are adapted to facilitate effective utilisation of environmental resources. Activity patterns are shaped by physiological constraints, evolutionary history, circadian and seasonal changes and may be influenced by other factors, including ecological competition and interspecific interactions. Remote-sensing camera traps allow the collection of species presence data throughout the 24 h period and for almost indefinite lengths of time. Read More

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November 2018
1 Read

Rocking the world of innate immunity: an interview with Luke O'Neill.

Authors:
Luke A J O'Neill

Dis Model Mech 2018 Nov 29;11(12). Epub 2018 Nov 29.

Luke O'Neill is professor of biochemistry in the School of Biochemistry and Immunology at Trinity College Dublin, and his main research focus is innate immunity and its key output, inflammation. His work has explored the key sensors and mediators of infection, including the Toll-like receptors, inflammasomes and cytokines in the interleukin-1 (IL-1) family. Luke received the Royal Irish Academy Gold Medal for Life Sciences in 2012 and the European Federation of Immunology Societies Medal in 2014. Read More

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November 2018

Group B streptococcal disease in UK and Irish infants younger than 90 days, 2014-15: a prospective surveillance study.

Lancet Infect Dis 2018 Nov 26. Epub 2018 Nov 26.

Paediatric Infectious Diseases Research Group & Vaccine Institute, St George's University of London and St George's University Hospitals NHS Trust, London, UK.

Background: Group B streptococcus is a leading cause of serious infection in young infants in many countries worldwide. We aimed to define the burden and clinical features of invasive group B streptococcal disease in infants younger than 90 days in the UK and Ireland, together with the characteristics of disease-causing isolates.

Methods: Prospective, active national surveillance of invasive group B streptococcal disease in infants younger than 90 days was done from April 1, 2014, to April 30, 2015, through the British Paediatric Surveillance Unit, microbiology reference laboratories, and national public health agencies in the UK and Ireland. Read More

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November 2018
1 Read

Barriers to progressing through a methadone maintenance treatment programme: perspectives of the clients in the Mid-West of Ireland's drug and alcohol services.

BMC Health Serv Res 2018 Nov 29;18(1):911. Epub 2018 Nov 29.

Graduate Entry Medical School, University of Limerick, Limerick, Ireland.

Background: The 'perfect' journey through an Irish Methadone Maintenance Treatment Programme (MMTP) would have a client engage appropriately with all relevant services available to them, inclusive of psychiatry, counselling, out-reach support, nursing and psychology. Concurrently, a client would ideally adhere to their prescribed methadone-dosing regimen, until a client is stabilised allowing them to function optimally. At this point, a client should transfer to the GP community setting. Read More

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November 2018
3 Reads

Neural activity related to volitional regulation of cortical excitability.

Elife 2018 Nov 29;7. Epub 2018 Nov 29.

Neural Control of Movement Lab, ETH Zürich, Zürich, Switzerland.

To date there exists no reliable method to non-invasively upregulate or downregulate the state of the resting human motor system over a large dynamic range. Here we show that an operant conditioning paradigm which provides neurofeedback of the size of motor evoked potentials (MEPs) in response to transcranial magnetic stimulation (TMS), enables participants to self-modulate their own brain state. Following training, participants were able to robustly increase (by 83. Read More

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November 2018
2 Reads

Diabetes Knowledge and Attitudes among Special Needs Assistants: A Pilot Study

Ir Med J 2018 May 10;111(5):763. Epub 2018 May 10.

Department of Paediatrics, Midland Regional Hospital, Mullingar, Co. Westmeath

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Acquired Factor Xiii Deficiency: An Uncommon But Easily Missed Cause Of Severe Bleeding

Ir Med J 2018 May 10;111(5):757. Epub 2018 May 10.

National Coagulation Centre, St. James’s Hospital, Dublin, Ireland

Factor XIII (FXIII) is a plasma clotting protein involved in clot stabilization. Severe FXIII deficiency may present with severe, even fatal bleeding. Critically however, routine coagulation assays may be normal and only specific FXIII assays will detect the abnormality. Read More

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Dementia Diagnosis and Referral in General Practice: A Representative Survey of Irish General Practitioners

Ir Med J 2018 Apr 19;111(4):735. Epub 2018 Apr 19.

Centre for Ageing, Neuroscience and the Humanities, Tallaght Hospital, Dublin Ireland

Aims Most of those with a memory problem or concern over cognition present to their General Practitioner (GP) in the first instance. Despite this, the current diagnostic and referral patterns of Irish GPs remains unclear. Methods A survey was distributed to three separate cohorts of GPs (n=692) Results Ninety-Five (14%) responded. Read More

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Do childhood psychotic experiences improve the prediction of adolescent psychopathology? A longitudinal population-based study.

Early Interv Psychiatry 2018 Nov 29. Epub 2018 Nov 29.

Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland.

Aims: (a) To investigate the utility of childhood PE as a predictor of adolescent psychopathology while accounting for three known risk factors: childhood mental disorder; traumatic experiences and poor childhood functioning, and (b) to investigate the additive effects of including childhood PE in predictive clinical model of adolescent psychopathology.

Method: The study sample comprised of 86 Irish youths who completed two waves of the "Adolescent Brain Development" study (baseline age: 11.7 and follow-up age: 15. Read More

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November 2018
1 Read

Antifungal activity of a de novo synthetic peptide and derivatives against fungal food contaminants.

J Pept Sci 2018 Nov 28:e3137. Epub 2018 Nov 28.

School of Food and Nutritional Sciences, University College Cork, Cork, Ireland.

The development of novel solutions to fight microbial food contaminants rests upon two pillars, which are the development of resistant strains and consumers' desire for a reduced consumption of synthetic drugs. Natural antimicrobial peptides possess the qualities to overcome these issues. De novo synthesis of novel antifungal compounds is a major progress that has been facilitated by the identification of parameters involved in the antimicrobial activity. Read More

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November 2018

Management of type 1 diabetes in primary schools in Ireland: a cross-sectional survey.

Ir J Med Sci 2018 Nov 28. Epub 2018 Nov 28.

Department of Paediatrics, Regional Hospital Mullingar, Mullingar, Co. Westmeath, Ireland.

Background: Parents reported experiences of support for diabetes management in schools are variable. Recent data from European countries are sparse and experiences in the Irish primary school setting have not been described previously.

Aim: To describe parents' experiences of support for diabetes management in primary schools in Ireland. Read More

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November 2018

Identification of Dual Receptor Binding Protein Systems in Lactococcal 936 Group Phages.

Viruses 2018 Nov 27;10(12). Epub 2018 Nov 27.

School of Microbiology & APC Microbiome Ireland, University College Cork, Western Road, Cork T12 YT20, Ireland.

of the lactococcal 936 group are the most commonly encountered bacteriophages in the dairy processing environment. The 936 group phages possess a discrete baseplate at the tip of their tail-a complex harbouring the Receptor Binding Protein (RBP) which is responsible for host recognition and attachment. The baseplate-encoding region is highly conserved amongst 936 phages, with 112 of 115 publicly available phages exhibiting complete synteny. Read More

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November 2018
4 Reads

A catalogue of the species of Mesostigmata (Arachnida, Acari, Parasitiformes) recorded from Ireland including information on their geographical distribution and habitats.

Zootaxa 2018 Nov 12;4519(1):1-220. Epub 2018 Nov 12.

School of Biology and Environmental Science, University College Dublin, Belfield, Dublin 4, Ireland..

The study of Irish Mesostigmata extends back for more than 100 years, and most of the principal Irish habitat types have been studied. In this paper we provide a catalogue of the species of Mesostigmata (Arachnida, Acari, Parasitiformes) recorded from Ireland over that time. The catalogue includes 329 species, information on the habitats and locations where they occurred and provides a comprehensive list of the literature related to the Irish fauna. Read More

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November 2018