6,221 results match your criteria Irish Journal of Medical Science [Journal]


Why our doctors are leaving Irish emergency medicine training.

Ir J Med Sci 2019 Feb 18. Epub 2019 Feb 18.

Royal College of Physicians of Ireland, Dublin, Ireland.

Background: In recent years, attrition from Emergency Medicine (EM) training in Ireland has increased. Australian data illustrates that increasing numbers of Irish-trained doctors are embarking on EM training in Australia. This has implications for EM in Ireland, particularly for Emergency Departments already under strain. Read More

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http://dx.doi.org/10.1007/s11845-019-01976-yDOI Listing
February 2019

Arthroscopic anterior shoulder stabilisation in overhead sport athletes: 5-year follow-up.

Ir J Med Sci 2019 Feb 15. Epub 2019 Feb 15.

Department of Trauma & Orthopaedic Surgery, Galway University Hospitals, Galway, Ireland.

Introduction: Shoulder instability following traumatic glenohumeral dislocation is a common injury sustained by athletes particularly in contact and collision sports. Overhead contact sports such as gaelic football and hurling pose a unique hazard to the glenohumeral joint, increasing the risk of dislocation.

Aims: To assess return to sport, level of play, recurrence and functional outcomes in gaelic football and hurling athletes in comparison with players of other sports. Read More

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http://dx.doi.org/10.1007/s11845-019-01986-wDOI Listing
February 2019
1 Read

Acute multiple sclerosis lesion pathology does not predict subsequent clinical course-a biopsy study.

Ir J Med Sci 2019 Feb 15. Epub 2019 Feb 15.

Department of Neuropathology, Beaumont Hospital, Beaumont Road, Dublin, Ireland.

Background: Knowledge of the clinical outcome in tumefactive demyelination remains limited.

Aims: This study aims to characterise the natural history of biopsy-proven, pathogen-free, cerebral demyelination in an adult Irish population.

Methods: We identified all patients with biopsy-proven demyelination in a single neuropathology centre between 1999 and 2017. Read More

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http://dx.doi.org/10.1007/s11845-019-01983-zDOI Listing
February 2019
2 Reads

Impact of the CYP2D6 phenotype on hyperprolactinemia development as an adverse event of treatment with atypical antipsychotic agents in pediatric patients.

Ir J Med Sci 2019 Feb 15. Epub 2019 Feb 15.

Discipline of Medical Genetics, Department of Microscopic Morphology, Victor Babeş University of Medicine and Pharmacy Timișoara, Timișoara, Romania.

Background: Treatment with atypical antipsychotics is today the election therapy for different types of psychosis, but there is a high incidence of endocrine and metabolic disturbances. One of the major enzymes involved in the metabolism of antipsychotics is CYP2D6. Depending on the existing CYP2D6 alleles, the metabolic capacity of the enzyme may vary from very low to very high, so that patients can be grouped into four phenotypic groups: slow, intermediate, extensive (normal), and fast metabolizers. Read More

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http://dx.doi.org/10.1007/s11845-019-01985-xDOI Listing
February 2019
1 Read

Twenty-four-hour urine NE level as a predictor of the therapeutic response to metoprolol in children with recurrent vasovagal syncope.

Ir J Med Sci 2019 Feb 13. Epub 2019 Feb 13.

Department of Pediatrics, Qilu Hospital, Shandong University, No. 107 Wenhuaxi Road, Jinan, 250012, Shandong Province, China.

Background: Vasovagal syncope (VVS) is a heterogeneous disorder that creates challenges for treatment. Metoprolol is an important therapeutic option for children with VVS.

Aims: The study examined the predictive value of 24-h urine norepinephrine (NE) levels in the assessment of the therapeutic efficacy of metoprolol for recurrent VVS in children. Read More

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http://dx.doi.org/10.1007/s11845-019-01979-9DOI Listing
February 2019
1 Read

Overexpression of apoptosis-related protein, survivin, in fibroblasts from patients with systemic sclerosis.

Ir J Med Sci 2019 Feb 13. Epub 2019 Feb 13.

Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Background/objectives: Recent studies suggest that, in addition to activation and hypersecretion of matrix components, fibroblasts from patients with systemic sclerosis (SSc) are resistant to apoptosis. Previous studies have shown that survivin, a member of inhibition of apoptosis (IAP) family, plays an important role in apoptosis resistance. Accordingly, we decided to study the expression of the most important members of IAP family in SSc fibroblasts, which can block apoptosis either by binding and inhibiting caspases or through caspase-independent mechanisms. Read More

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http://dx.doi.org/10.1007/s11845-019-01978-wDOI Listing
February 2019

Quantification of the impact of interventional radiology in the management of acute pancreatitis.

Ir J Med Sci 2019 Feb 13. Epub 2019 Feb 13.

Department of Radiology, Tallaght University Hospital, Dublin 24, Ireland.

Objectives: Interventional radiology plays a central role in the management of complicated acute pancreatitis, contributing to image-guided drainages, treating haemorrhagic complications and maintaining the patency of the biliary tree. In addition, many of these patients require long-term venous access for antibiotics or parenteral feeding. The aim of this study was to evaluate the role and level of involvement of the interventional radiology in this sub-group of patients. Read More

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http://dx.doi.org/10.1007/s11845-019-01970-4DOI Listing
February 2019
1 Read

An analysis of childhood consultations in general practice: a multi-practice study.

Ir J Med Sci 2019 Feb 12. Epub 2019 Feb 12.

University of Limerick Graduate Entry Medical School, Castletroy, Limerick, Ireland.

Background: The majority of illnesses in children are managed by general practitioners (GPs) and there is a need for up to date data on consultations with children in order to improve healthcare service planning and allocation of resources.

Aims: To investigate the presenting symptoms, diagnoses and actions taken by the GP at consultations with children in general practice.

Methods: Senior medical students on general practice placement and their GP supervisors used practice management software to collect data on 100 randomly selected patients aged between 12 months and 14 years of age in each practice. Read More

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http://dx.doi.org/10.1007/s11845-019-01982-0DOI Listing
February 2019

Utilisation of critical care services for surgical patients in a model three hospital.

Ir J Med Sci 2019 Feb 9. Epub 2019 Feb 9.

Department of General Surgery, Mayo University Hospital, Castlebar, Co. Mayo, Ireland.

Background: The demand for intensive care unit (ICU) beds in the surgical population has increased in recent years. This is due to increased complexity of operative interventions, development of critical care services and improved availability of technologies. The number of beds in ICUs nationwide remains limited. Read More

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http://dx.doi.org/10.1007/s11845-019-01981-1DOI Listing
February 2019

GDPR: an impediment to research?

Ir J Med Sci 2019 Feb 8. Epub 2019 Feb 8.

Beaumont Hospital Ethics (Medical Research) Committee, Beaumont Hospital, Dublin, Ireland.

Background: The recent introduction of the General Data Protection Regulation and Health Research Regulations has been an area of significant concern for those engaged in clinical research. These European regulations, following subsequent interpretation by Ireland's Department of Health, now place Ireland in a unique position which differs substantially from other European countries and may prove a significant impediment to Irish clinical research, depriving Irish patients of timely access to potentially life-saving treatments and making Ireland less attractive to pharmaceutical companies engaged in this area. At the very least, the regulations, as applied in Ireland, will place a significant extra burden of work on Ireland's clinical researchers and at their worst will force individuals and institutions out of the clinical research field, which will result in significant loss to the Irish knowledge economy and lead to the detriment of patient care. Read More

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http://link.springer.com/10.1007/s11845-019-01980-2
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http://dx.doi.org/10.1007/s11845-019-01980-2DOI Listing
February 2019
5 Reads

The long-term outcomes following internal fixation for intracapsular hip fractures in an Irish tertiary referral centre.

Ir J Med Sci 2019 Feb 2. Epub 2019 Feb 2.

Department of Trauma and Orthopaedic Surgery, University Hospital Galway, Galway, Ireland.

Background: The burden associated with hip fractures is increasing worldwide. Arthroplasty procedures are more commonly performed for intracapsular fractures due to increased risk of compromise to the femoral head blood supply. However, we know from the Irish Hip Fracture Database that a significant proportion of these fractures undergo internal fixation. Read More

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http://dx.doi.org/10.1007/s11845-019-01972-2DOI Listing
February 2019
2 Reads

Ward stories: lessons learned from patient perception of the ward round.

Ir J Med Sci 2019 Feb 2. Epub 2019 Feb 2.

St Vincent's University Hospital, Dublin, Ireland.

Introduction: Ward rounds (WR) are an invaluable part of the hospital day allowing for daily assessment of each patient and their treatment, perhaps the most crucial role of the WR is information transfer.

Purpose: This study investigated inpatient's perception of the cardiology and urology WR; in particular, it examined patient-doctor communication.

Methods: Inpatients were interviewed to explore pertinent areas concerning the WR; a questionnaire was subsequently developed which analysed four aspects: information-giving and communication, emotional reaction, professionalism, and privacy. Read More

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http://dx.doi.org/10.1007/s11845-019-01975-zDOI Listing
February 2019

The role of real-time PCR testing in the investigation of paediatric patients with community-onset osteomyelitis and septic arthritis.

Ir J Med Sci 2019 Jan 31. Epub 2019 Jan 31.

Irish Meningitis and Sepsis Reference Laboratory, Temple Street Children's University Hospital, Dublin 1, Ireland.

Background: Culture yield in osteomyelitis and septic arthritis is low, emphasising the role for molecular techniques.

Aims: The purpose of this study was to review the laboratory investigation of childhood osteomyelitis and septic arthritis.

Methods: A retrospective review was undertaken in an acute tertiary referral paediatric hospital from January 2010 to December 2016. Read More

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http://link.springer.com/10.1007/s11845-019-01973-1
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http://dx.doi.org/10.1007/s11845-019-01973-1DOI Listing
January 2019
3 Reads

Clinical impact of rapid polymerase chain reaction (PCR) test for group B Streptococcus (GBS) in term women with ruptured membranes.

Ir J Med Sci 2019 Jan 31. Epub 2019 Jan 31.

Department of Microbiology, National Maternity Hospital, Holles Street, Dublin 2, Ireland.

Background: Early-onset group B Streptococcus (EOGBS/GBS) infection remains a significant cause of neonatal morbidity and mortality.

Aims: Aiming to improve antimicrobial stewardship and reduce unnecessary maternal and infant exposure to intrapartum antibiotic prophylaxis (IAP), this study assessed the clinical use of a commercially available GBS polymerase chain reaction (PCR) assay for term women with pre-labour rupture of membranes.

Methods: This was a retrospective study in a tertiary level maternity unit of term women with pre-labour rupture of membranes (ROM), without any clinical suspicion of infection performed between November and December 2017. Read More

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http://dx.doi.org/10.1007/s11845-019-01977-xDOI Listing
January 2019

Incidence and outcome of interrupted geriatric rehabilitation requiring acute hospital transfer.

Ir J Med Sci 2019 Jan 25. Epub 2019 Jan 25.

Department of Medicine for the Elderly, St Mary's Hospital, Phoenix Park, Dublin, Ireland.

Background And Aims: Elderly rehabilitation programs provide a period of rehabilitation to optimize a safe home discharge after acute hospitalization of older adults. Often, these patients may have their rehabilitation interrupted when they become unwell and subsequently require transfer back to an acute hospital setting. We will look at the incidence and outcome of this interruption. Read More

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http://dx.doi.org/10.1007/s11845-019-01974-0DOI Listing
January 2019
1 Read

Spectrum of rhabdomyolysis in an acute hospital.

Ir J Med Sci 2019 Jan 24. Epub 2019 Jan 24.

Department of Nephrology, Tallaght University Hospital, Dublin 24, Ireland.

Rhabdomyolysis is a state of muscle necrosis with the hallmark being elevated creatine kinase that may cause acute kidney injury with serious consequences. It happens in many clinical settings. We sought to investigate all cases of rhabdomyolysis admitted to an acute hospital in Ireland over one calendar year. Read More

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http://dx.doi.org/10.1007/s11845-019-01968-yDOI Listing
January 2019

Packing versus mushroom catheters following incision and drainage in anorectal abscess.

Ir J Med Sci 2019 Jan 23. Epub 2019 Jan 23.

Department of Surgery, Cork University Hospital, Wilton Road, Cork, Ireland.

Purpose: Management of anorectal abscess is traditionally by incision and drainage with packing. This study assessed the use of mushroom catheters compared with packing of anorectal abscess after incision and drainage in adults. Placement of a mushroom catheter to allow ongoing drainage of the cavity may have advantages by eliminating the need for painful dressing changes. Read More

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http://link.springer.com/10.1007/s11845-018-01958-6
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http://dx.doi.org/10.1007/s11845-018-01958-6DOI Listing
January 2019
18 Reads

Room 101: are gender-specific cigarette packets the way forward?

Ir J Med Sci 2019 Jan 21. Epub 2019 Jan 21.

Hauora Tairawhiti, Gisborne, New Zealand.

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http://dx.doi.org/10.1007/s11845-019-01971-3DOI Listing
January 2019

Satisfaction of the Irish Trauma and Orthopaedic training programme with the Intercollegiate Surgical Curriculum Programme.

Ir J Med Sci 2019 Jan 21. Epub 2019 Jan 21.

Waterford University Hospital, Waterford, Ireland.

Background: Surgical training has undergone extensive changes in recent years. The Intercollegiate Surgical Curriculum Programme (ISCP) has been utilised in the UK for many years to facilitate the education and assessment of trainees. It was adopted by the Irish Trauma and Orthopaedics (T&O) training programme in July 2015. Read More

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http://dx.doi.org/10.1007/s11845-019-01966-0DOI Listing
January 2019

The dangers of hurling-genital injuries arising in the modern game.

Ir J Med Sci 2019 Jan 19. Epub 2019 Jan 19.

Department of Urology, University Hospital Waterford, Waterford, Ireland.

Objective: To assess the proportion of penoscrotal injuries arising from the sport of hurling and to assess work-up and management of each injury.

Methods: Using Hospital In-Patient Enquiry data, all penoscrotal injuries occurring over a 10-year period between 2007 and 2017 were identified and assessed. Chart review, imaging reports, operative notes and discharge summaries were used to identify the aetiology of each injury and those occurring due to hurling were selected for analysis. Read More

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http://dx.doi.org/10.1007/s11845-019-01969-xDOI Listing
January 2019
2 Reads

Food-dependent exercise-induced reactions: lessons from a 15-year retrospective study.

Ir J Med Sci 2019 Jan 19. Epub 2019 Jan 19.

Department of Immunology, St. James's Hospital, Dublin, Ireland.

Background: Food-dependent exercise-induced anaphylaxis (FDEIA) is a life-threatening disorder in which the signs and symptoms of anaphylaxis occur if physical exertion occurs within a few hours of exposure to a food.

Aims: The aim of this study was to characterise patients diagnosed with FDEIA and related disorders.

Methods: A retrospective review of electronic clinical data from 2001 to 2016 was carried out. Read More

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http://dx.doi.org/10.1007/s11845-019-01965-1DOI Listing
January 2019
1 Read

The Great Irish Famine (1845-52) and the Irish asylum system: remembering, forgetting, and remembering again.

Authors:
Brendan D Kelly

Ir J Med Sci 2019 Jan 16. Epub 2019 Jan 16.

Department of Psychiatry, Trinity College Dublin, Trinity Centre for Health Sciences, Tallaght University Hospital, Dublin 24, D24 NR0A, Ireland.

The Great Irish Famine (1845-52) saw the Irish population fall by 20% as one million people died and another million emigrated. The Famine occurred at a time when the Irish asylums were growing rapidly anyway, so its precise effects on mental health are difficult although not impossible to study. Three groups merit consideration. Read More

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http://dx.doi.org/10.1007/s11845-019-01967-zDOI Listing
January 2019
1 Read

Obesity cardiomyopathy: the role of obstructive sleep apnea and obesity hypoventilation syndrome.

Ir J Med Sci 2019 Jan 15. Epub 2019 Jan 15.

Respiratory Division, University Hospital Limerick, Limerick, Ireland.

The negative long-term health consequences of obesity are well known to both the medical profession and general public. Despite this, the number of obese and overweight individuals worldwide continues to steadily rise. Although obesity has long been associated with an increased risk for cardiovascular disease and mortality, the classification of a cardiomyopathy of obesity is a more recent development. Read More

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http://link.springer.com/10.1007/s11845-018-01959-5
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http://dx.doi.org/10.1007/s11845-018-01959-5DOI Listing
January 2019
14 Reads

Profiling frequent attenders at an inner city emergency department.

Ir J Med Sci 2019 Jan 11. Epub 2019 Jan 11.

Emergency Department, Mercy University Hospital, Cork, Ireland.

Background: Emergency department (ED) frequent attenders (FAs) have a higher rate of adverse outcomes compared to infrequent attenders.

Aims: The primary aim was to describe the prevalence of FAs at an inner city ED. A subgroup analysis was undertaken for high and very high FAs to establish demographics and other factors which might cause them to attend frequently. Read More

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http://dx.doi.org/10.1007/s11845-019-01964-2DOI Listing
January 2019

The clinical characteristics and correlates of lithium toxicity in a tertiary referral centre.

Ir J Med Sci 2019 Jan 10. Epub 2019 Jan 10.

Department of Psychiatry, University Hospital Galway, Galway, Ireland.

Introduction: Lithium is a medication indicated for the treatment of bipolar disorder and treatment-resistant depression, with a narrow therapeutic index. Overdose, either acute or chronic can result in neurological symptoms, requiring dialysis and admission to intensive care in some cases. Lithium toxicity is avoidable with careful monitoring. Read More

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http://dx.doi.org/10.1007/s11845-018-01963-9DOI Listing
January 2019
2 Reads

Worldwide scientific production in obstetrics: a bibliometric analysis.

Ir J Med Sci 2019 Jan 9. Epub 2019 Jan 9.

Cátedra de Medicina de Familia, Clinical Medicine Department, Miguel Hernandez University, Ctra. Nnal. 332 Alicante-Valencia s/n, 03550, San Juan de Alicante, Alicante, Spain.

Background: Randomised clinical trials are considered to be the most reliable study design for assessing the efficacy and safety of health interventions.

Aims: To analyse worldwide obstetrics research carried out through randomised clinical trials, from 2002 to 2013.

Methods: A bibliometric analysis was performed. Read More

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http://link.springer.com/10.1007/s11845-018-1954-3
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http://dx.doi.org/10.1007/s11845-018-1954-3DOI Listing
January 2019
11 Reads

Comparison of 4 different techniques in first metatarsophalangeal joint arthrodesis.

Ir J Med Sci 2019 Jan 8. Epub 2019 Jan 8.

Orthopaedic Department, St. James's Hospital, James's Street, Dublin, D08 NHY1, Ireland.

Aims: The aim of this study was to evaluate outcomes and fusion rates of 4 different methods of first metatarsophalangeal joint (MTPJ) arthrodesis.

Methods: We performed a retrospective analysis of first MTPJ fusion using Bold® and Acutrak® compression screws, universal 1/3 tubular plate and Hallu®-S non-locking plate in 6 hospitals in Dublin over 4 years. A cohort of 300 patients (351 feet) was operated on by 3 feet and ankle fellowship trained orthopaedic surgeons (PK, MMS, JVMcK) over 4 years. Read More

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http://dx.doi.org/10.1007/s11845-018-01961-xDOI Listing
January 2019
1 Read
0.573 Impact Factor

Appropriate use of elective coronary angiography in patients with suspected stable coronary artery disease.

Ir J Med Sci 2019 Jan 5. Epub 2019 Jan 5.

School of Public Health, University College Cork, 4th Floor, Western Gateway Building, Western Road, Cork, Ireland.

Introduction: The American College of Cardiology Foundation (ACCF) with other professional societies developed appropriate use criteria (AUC) for diagnostic coronary angiography. This study aims to examine the appropriate use of elective coronary angiography for patients with suspected stable coronary artery disease in an Irish tertiary referral center.

Methods: A retrospective chart review of all elective outpatient diagnostic coronary angiograms performed in Cork University Hospital in 2014 was carried out. Read More

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http://dx.doi.org/10.1007/s11845-018-1953-4DOI Listing
January 2019
2 Reads

Prevalence of sarcopenia in patients with geriatric depression diagnosis.

Ir J Med Sci 2019 Jan 4. Epub 2019 Jan 4.

Neurology, Ordu State Hospital, Ordu, Turkey.

Aim: In this study, the aim was to identify the prevalence of sarcopenia among patients with geriatric depression (GD) diagnosis and to collect data to illuminate precautions to reduce disease load.

Method: The study was completed with 116 patients (GD group) aged 65 years or older with possible or definite depression diagnosis according to the Geriatric Depression Scale (GDS) criteria and 301 volunteers aged from 18 to 39 years (control 1) and above 65 years (control 2). Our prospective and cross-sectional study applied the Hamilton Depression Rating Scale (HDRS) to control 1 group and the GDS and Mini Mental Test (MMSE) to control 2 and GD groups. Read More

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http://dx.doi.org/10.1007/s11845-018-01957-7DOI Listing
January 2019
1 Read

Risk factors for miscarriage among women attending an early pregnancy assessment unit (EPAU): a prospective cohort study.

Ir J Med Sci 2019 Jan 3. Epub 2019 Jan 3.

Pregnancy Loss Research Group, Department of Obstetrics and Gynaecology, University College Cork, Cork, Ireland.

Background: Miscarriage is the most common adverse outcome in early pregnancy; however, high proportion of miscarriages are classified as unexplained. In addition, pregnant women attending early pregnancy assessment units might be more vulnerable.

Aims: The purpose of this study was to explore the risk factors that might be associated with miscarriage among women attending an early pregnancy assessment unit (EPAU). Read More

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http://link.springer.com/10.1007/s11845-018-1955-2
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http://dx.doi.org/10.1007/s11845-018-1955-2DOI Listing
January 2019
5 Reads

Burning mouth syndrome-a diagnostic dilemma.

Ir J Med Sci 2019 Jan 2. Epub 2019 Jan 2.

Cork University Dental School and Hospital, Wilton, Cork, Ireland.

Background: Burning mouth syndrome (BMS) is a chronic pain disorder, more common in peri and postmenopausal females, with a varied symptomatology. Symptoms include a burning or stinging sensation of the tongue, lips or other oral mucosal surfaces, subjectively dry mouth or excess saliva, altered taste or loss of taste and paraesthetic sensations. These are usually present daily for more than 3 months. Read More

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http://link.springer.com/10.1007/s11845-018-01960-y
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http://dx.doi.org/10.1007/s11845-018-01960-yDOI Listing
January 2019
4 Reads

UCD School of Medicine Summer Student Research Awards 2018.

Authors:

Ir J Med Sci 2018 Nov;187(Suppl 11):325-354

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http://dx.doi.org/10.1007/s11845-018-1941-8DOI Listing
November 2018
1 Read

Total hip replacement-the cause of failure in patients under 50 years old?

Ir J Med Sci 2018 Dec 19. Epub 2018 Dec 19.

Department of Orthopaedic Surgery, Cappagh National Orthopaedic Hospital, Dublin, Ireland.

Aim: To establish the mode of failure of primary total hip replacement in patients under 50 years old.

Methods: A total of 1062 revision total hip arthroplasties were performed over a 5-year period, with 146 on patients under 50 years old. These were subdivided into early (< 5 years) and late (> 5 years) failures from the index procedure. Read More

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http://link.springer.com/10.1007/s11845-018-01956-8
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http://dx.doi.org/10.1007/s11845-018-01956-8DOI Listing
December 2018
12 Reads

Self-confidence and clinical skills: the case of students who study medicine in English in a non-English speaking setting.

Ir J Med Sci 2018 Dec 19. Epub 2018 Dec 19.

Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Visegradska 26A, Belgrade, 11000, Serbia.

Background: An increasing number of international students has been enrolling in medical studies in the English language offered by the countries of Eastern Europe. Development of practical skills is likely more challenging when students learn in the English language, while their patients are non-English speaking persons.

Aims: To evaluate self-perception of practical skills of medical students in the English language program. Read More

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http://link.springer.com/10.1007/s11845-018-1947-2
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http://dx.doi.org/10.1007/s11845-018-1947-2DOI Listing
December 2018
6 Reads

Dialysis independence following single-agent daratumumab in refractory myeloma with renal failure.

Ir J Med Sci 2018 Dec 19. Epub 2018 Dec 19.

Department of Haematology, Beaumont Hospital, Dublin 9, Beaumont, Ireland.

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http://dx.doi.org/10.1007/s11845-018-1951-6DOI Listing
December 2018
2 Reads

Obesity and cardiovascular risk in an oncology day ward population.

Ir J Med Sci 2018 Dec 18. Epub 2018 Dec 18.

Department of Oncology, Waterford University Hospital, Waterford, Ireland.

Introduction: The burden of obesity and risk of cardiovascular (CV) disease amongst an oncology population receiving active treatment is ill-defined. We performed a retrospective analysis assessing the incidence of obesity and cardiovascular (CV) risk factors in this group (grp) of patients as well as the predicted 10-year risk of a CV event.

Methods: Data from all patients (pts) receiving intravenous chemotherapy in an Irish oncology satellite unit over an 18-month period was extracted from chemotherapy prescriptions and electronic patient records. Read More

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http://dx.doi.org/10.1007/s11845-018-1950-7DOI Listing
December 2018

Equestrian injuries presenting to a regional trauma centre in Ireland.

Ir J Med Sci 2018 Dec 18. Epub 2018 Dec 18.

Department of Trauma and Orthopaedic Surgery, Midland Regional Hospital Tullamore, Tullamore, Ireland.

Background: The Irish equestrian industry provides over 12,500 full-time jobs and contributes in excess of €454 million to the Irish exchequer annually. For such a vital industry, there is a dearth of information relating to equestrian-associated injuries.

Aims: The aim of this study was to determine the demographics, characteristics and outcomes of equestrian-related injuries presenting to the emergency department of a regional trauma centre in Ireland over the course of 1 year. Read More

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http://dx.doi.org/10.1007/s11845-018-1952-5DOI Listing
December 2018
1 Read

Primary total hip arthroplasty: registry data for fixation methods and bearing options at a minimum of 10 years.

Ir J Med Sci 2018 Dec 17. Epub 2018 Dec 17.

Cappagh National Orthopaedic Hospital, Finglas, Dublin 11, Ireland.

Background: Registry data for total hip arthroplasty (THA) has allowed optimal fixation methods, bearing surfaces and many other factors to be assessed. We describe 10-year THA outcomes from an Irish perspective using regional THA registry data for the first time.

Aims: We assess the main predictors of revision in primary total hip arthroplasty (THA) using regional registry data. Read More

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http://dx.doi.org/10.1007/s11845-018-1948-1DOI Listing
December 2018
1 Read

Parental awareness of newborn bloodspot screening in Ireland.

Ir J Med Sci 2018 Dec 15. Epub 2018 Dec 15.

Graduate Entry Medical School and Centre for Interventions in Infection, Inflammation & Immunity (4i), University of Limerick, Limerick, Ireland.

Background: There is little known regarding how familiar parents are with the newborn bloodspot screening (NBS) test or how well parents of a child with a screen-detected condition understand that condition initially.

Aim: The study aim was to examine parental NBS awareness and conditions screened.

Methods: Two studies were conducted: [1] Parents of children with cystic fibrosis (CF) detected via NBS and subsequently, diagnosed (n = 124) completed a telephone questionnaire regarding information they received at the time of NBS. Read More

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http://link.springer.com/10.1007/s11845-018-1949-0
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http://dx.doi.org/10.1007/s11845-018-1949-0DOI Listing
December 2018
12 Reads

Transmission electron microscopy and histological analysis of the peridural membrane.

Ir J Med Sci 2018 Dec 15. Epub 2018 Dec 15.

Department of Orthopaedics, University Hospital Galway, Newcastle Road, Galway, Ireland.

Introduction: While first described in 1904, the characterisation of the peridural membrane, which is frequently encountered, yet usually unnoticed, during lumbar decompression surgery, remains inconclusive. This relatively little known membrane is continuous with the posterior longitudinal ligament and lines the epidural space. In this study, we are comparing the membrane and ligamentum flavum from patients to analyse the variations of the histological and ultrastructural compositions. Read More

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http://dx.doi.org/10.1007/s11845-018-1940-9DOI Listing
December 2018
2 Reads

Achieving proficiency in rigid bronchoscopy-a study in manikins.

Ir J Med Sci 2018 Dec 14. Epub 2018 Dec 14.

Department of Anaesthesia, The Rotunda Hospital, Parnell Square, Dublin, Ireland.

Background: Rigid bronchoscopy may be used to relieve acute airway obstruction following induction of anaesthesia and is a recommended option for management of the difficult airway. The ability of anaesthetists to perform rigid bronchoscopy has not been reported. We sought to explore the acquisition of procedural skill in rigid bronchoscopy by anaesthesiologists in a manikin. Read More

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http://link.springer.com/10.1007/s11845-018-1944-5
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http://dx.doi.org/10.1007/s11845-018-1944-5DOI Listing
December 2018
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The role of increased synovial fluid A disintegrin and metalloproteinase with thrombospondin motifs4 and serglycin levels in osteoarthritis.

Authors:
Kenan Özler

Ir J Med Sci 2018 Dec 7. Epub 2018 Dec 7.

Konya Beysehir State Hospital, Beyşehir Devlet Hastanesi, 042100, Konya, Turkey.

Background: The first research to determine synovial fluid ADAMTS4 and serglycin levels in osteoarthritis and OA progression.

Aim: We aimed to determine ADAMTS4 and serglycin levels, interactions, and changes in the synovial fluid of knee OA, and also to determine effective in OA progression.

Methods: A case-control study was carried out including a total of 88 participants (29 patients late OA [LOA], 28 early OA [EOA], and 30 controls). Read More

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http://dx.doi.org/10.1007/s11845-018-1945-4DOI Listing
December 2018
1 Read

Acute ischaemic stroke: a systematic review of the cost-effectiveness of emergency endovascular therapy using mechanical thrombectomy.

Ir J Med Sci 2018 Dec 8. Epub 2018 Dec 8.

Health Information and Quality Authority, George's Court, George's Lane, Dublin, D07 E98Y, Ireland.

Purpose: Although good evidence exists regarding the clinical effectiveness of mechanical thrombectomy for people with acute ischaemic stroke, cost-effectiveness should also be considered. The aim of this study was to systematically review the evidence of cost-effectiveness of emergency endovascular therapy using mechanical thrombectomy in the management of acute ischaemic stroke.

Methods: The search was carried out in PubMed, EMBASE, Cochrane Library, and a grey literature search. Read More

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http://dx.doi.org/10.1007/s11845-018-1946-3DOI Listing
December 2018

Gender impact on the correlations between Graves' hyperthyroidism and hyperuricemia in Chinese.

Ir J Med Sci 2018 Nov 30. Epub 2018 Nov 30.

Department of Health Management, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.

Objective: An increased level of serum uric acid (SUA) can be observed in patients with hypothyroidism. Nonetheless, data on the relationship between hyperuricemia and hyperthyroidism was still controversial. Thus, we aimed to analyze the association between Graves' hyperthyroidism and hyperuricemia in Chinese men and women. Read More

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http://dx.doi.org/10.1007/s11845-018-1939-2DOI Listing
November 2018
2 Reads

Evaluation of the specificity of the central diagnostic criterion for chronic traumatic encephalopathy.

Ir J Med Sci 2018 Nov 30. Epub 2018 Nov 30.

Department of Neuropathology, Beaumont Hospital, Beaumont Road, Dublin 9, Ireland.

Introduction: Chronic traumatic encephalopathy (CTE) is a postmortem diagnosis. Consensus postmortem, but not antemortem, diagnostic criteria have been established. A key factor in these criteria is evidence of phosphorylated-tau (p-tau) around sulcal vessels in the cortex. Read More

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http://dx.doi.org/10.1007/s11845-018-1943-6DOI Listing
November 2018
1 Read

Current concepts on bibliometrics: a brief review about impact factor, Eigenfactor score, CiteScore, SCImago Journal Rank, Source-Normalised Impact per Paper, H-index, and alternative metrics.

Ir J Med Sci 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurochemistry, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.

Background: Understanding the impact of a publication by using bibliometric indices becomes an essential activity not only for universities and research institutes but also for individual academicians. This paper aims to provide a brief review of the current bibliometric tools used by authors and editors and proposes an algorithm to assess the relevance of the most common bibliometric tools to help the researchers select the fittest journal and know the trends of published submissions by using self-evaluation.

Methods: We present a narrative review answering at least two related consecutive questions triggered by the topics mentioned above. Read More

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http://dx.doi.org/10.1007/s11845-018-1936-5DOI Listing
December 2018
1 Read

Management of type 1 diabetes in primary schools in Ireland: a cross-sectional survey.

Ir J Med Sci 2018 Nov 28. Epub 2018 Nov 28.

Department of Paediatrics, Regional Hospital Mullingar, Mullingar, Co. Westmeath, Ireland.

Background: Parents reported experiences of support for diabetes management in schools are variable. Recent data from European countries are sparse and experiences in the Irish primary school setting have not been described previously.

Aim: To describe parents' experiences of support for diabetes management in primary schools in Ireland. Read More

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http://dx.doi.org/10.1007/s11845-018-1942-7DOI Listing
November 2018

Moving from peripheral blood to local uterine immunophenotype analysis in patients with poor reproductive history: pilot study of a novel technique.

Ir J Med Sci 2018 Nov 27. Epub 2018 Nov 27.

Sims IVF Clinic, Clonskeagh Road, Clonskeagh, Dublin 14, Ireland.

Background: A complete reproductive immunophenotype is poorly described, with most focus on peripheral blood natural killer cells rather than uterine populations. There is debate regarding normal endometrial levels, with no consensus, and much controversy on correlation with implantation/miscarriage.

Aims: Development and validation of a rapid endometrial assessment flow cytometry (FCM) technique, allowing determination of local lymphocyte subset ranges, comparison to peripheral blood, and patient subgroup analysis. Read More

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http://dx.doi.org/10.1007/s11845-018-1933-8DOI Listing
November 2018
1 Read

Fluid and electrolyte balance-establishing the knowledge base of Foundation Year One doctors.

Ir J Med Sci 2018 Nov 27. Epub 2018 Nov 27.

Epsom and St Helier University Hospitals NHS Trust, London, UK.

Background: Fluid and electrolyte management for hospital inpatients has been identified by multiple reports to be suboptimal, with delegation of this task to the most junior members of a medical team, Foundation Year One (FY1) doctors, also known as interns or house officers, being identified as a contributing factor.

Methods: An online survey was distributed nationally via social media to FY1 doctors between 21st August 2018 and 19th September 2018. Questions focused around cohort characteristics, team behaviours around fluid and electrolyte prescribing, as well as teaching and knowledge. Read More

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http://dx.doi.org/10.1007/s11845-018-1937-4DOI Listing
November 2018