113,726 results match your criteria Iodine Deficiency


Accuracy of Calcium Scoring calculated from contrast-enhanced Coronary Computed Tomography Angiography using a dual-layer spectral CT: A comparison of Calcium Scoring from real and virtual non-contrast data.

PLoS One 2018 6;13(12):e0208588. Epub 2018 Dec 6.

Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Purpose: Modern non-invasive evaluation of Coronary Artery Disease (CAD) requires non-contrast low dose Computed Tomography (CT) imaging for determination of Calcium Scoring (CACS) and contrast-enhanced imaging for evaluation of vascular stenosis. Several methods for calculation of CACS from contrast-enhanced images have been proposed before. The main principle for that is generation of virtual non-contrast images by iodine subtraction from a contrast-enhanced spectral CT dataset. Read More

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December 2018
1 Read

Alpha7 acetylcholine receptor autoantibodies are rare in sera of patients diagnosed with schizophrenia or bipolar disorder.

PLoS One 2018 6;13(12):e0208412. Epub 2018 Dec 6.

Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands.

The α7 acetylcholine receptor (AChR) has been linked with the onset of psychotic symptoms and we hypothesized therefore that it might also be an autoimmune target. Here, we describe a new radioimmunoassay (RIA) using iodine 125-labelled α-bungarotoxin and membrane extract from transfected HEK293 cells expressing human α7 AChR. This RIA was used to analyze sera pertaining to a cohort of 711 subjects, comprising 368 patients diagnosed with schizophrenia spectrum disorders, 140 with bipolar disorder, 58 individuals diagnosed of other mental disorders, and 118 healthy comparison subjects. Read More

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December 2018
5 Reads

Chinese Expert Consensus Workshop Report: Guideline for permanent iodine-125 seed implantation of primary and metastatic lung tumors.

Thorac Cancer 2018 Dec 6. Epub 2018 Dec 6.

Department of Interventional Medicine, The Second Hospital of Shandong University, Jinan, China.

Surgery remains the first choice of cure for early stage lung cancer. However, many patients are diagnosed at advanced stage, and thus miss the opportunity to undergo surgery. As such patients derive limited benefits from chemotherapy or radiotherapy, alternatives focusing on local control have emerged, including iodine-125 seed implantation. Read More

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December 2018

Development of bismuth-functionalized graphene oxide to remove radioactive iodine.

Dalton Trans 2018 Dec 6. Epub 2018 Dec 6.

Division of Advanced Nuclear Engineering (DANE), Pohang University of Science and Technology (POSTECH), 77 Chongam-ro, Nam-Gu, Pohang 790-784, Republic of Korea.

Bismuth-functionalized graphene oxide (Bi-GO) was successfully synthesized and showed both high iodide and iodate removal efficiencies from radioactive wastewater. Batch experiments for kinetic and selectivity tests were performed, respectively. Additional SEM, XRD, FT-IR, and XPS analyses were performed for characterization of a sorbent and bismuth on the GO surface and this confirmed that bismuth on the GO surface reacted with iodine species by surface complexation (or precipitation). Read More

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December 2018

A gold nanorod-based plasmonic platform for multi-logic operation and detection.

Nanotechnology 2019 Feb;30(5):055503

College of Chemistry, Beijing Normal University, Beijing 100875, People's Republic of China.

A multi-logic gate platform was designed based on morphological changes of gold nanorods (AuNRs) resulted from the iodine-mediated etching. By utilizing the anti-etching effects of mercapto compounds and Au-Hg amalgams as well as the etch-promoting effect of Cu, we successfully built five logic gates, namely, AND, NOR, XNOR, YES and IMPLY, along with a three-input combinational logic gate XNOR-IMPLY. The platform was versatile and easy to use, did not require complex surface modification or separation/purification steps as the conventional AuNR-based logic gates did. Read More

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February 2019
2 Reads

Enantiospecific Synthesis of ortho-Substituted 1,1-Diarylalkanes by a 1,2-Metalate Rearrangement/anti-SN2' Elimination/Rearomatizing Allylic Suzuki-Miyaura Reaction Sequence.

Angew Chem Int Ed Engl 2018 Dec 6. Epub 2018 Dec 6.

Bristol University, Department of Chemistry, Cantock's Close, BS8 1TS, Bristol, UNITED KINGDOM.

The one-pot sequential coupling of benzylamines, boronic esters and aryl iodides has been investigated. In the presence of an N-activator, the boronate complex formed from an ortho-lithiated benzylamine and a boronic ester undergoes stereospecific 1,2-metalate rearrangement/anti-SN2' elimination to form a dearomatized tertiary boronic ester. Treatment with an aryl iodide under palladium catalysis leads to rearomatizing γ-selective allylic Suzuki-Miyaura cross-coupling to generate 1,1-diarylalkanes. Read More

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December 2018

Disinfection effect of povidone-iodine in aquaculture water of swamp eel ().

PeerJ 2018 29;6:e5523. Epub 2018 Nov 29.

College of Biological Science and Engineering, Jiangxi Agricultural University, Nanchang, China.

The swamp eel () is an important commercial farmed fish species in China. However, it is susceptible to infections, resulting in high mortality and considerable economic loss. Povidone-iodine (PVP-I) is a widely used chemical disinfectant in aquaculture, which can decrease the occurrence of diseases and improve the survival. Read More

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November 2018
1 Read

Large variations in the practice patterns of surgical antiseptic preparation solutions in patients with open and closed extremity fractures: a cross-sectional survey.

Antimicrob Resist Infect Control 2018 29;7:148. Epub 2018 Nov 29.

3Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON Canada.

Background: Surgically-managed fractures, particularly open fractures, are associated with high rates of surgical site infections (SSIs). To reduce the risk of an SSI, orthopaedic surgeons routinely clean open fracture wounds in the emergency department (ED) and then apply a bandage to the open wound. Prior to the surgical incision, it is standard practice to prepare the fracture region with an antiseptic skin solution as an additional SSI prevention strategy. Read More

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November 2018
2 Reads

Thrombotic Microangiopathy with Severe Proteinuria Induced by Lenvatinib for Radioactive Iodine-Refractory Papillary Thyroid Carcinoma.

Case Rep Oncol 2018 Sep-Dec;11(3):735-741. Epub 2018 Nov 12.

Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

Standard therapy for radioactive iodine (RAI)-refractory differentiated thyroid cancer (DTC) is multi-targeted kinase inhibitors (m-TKIs), represented by sorafenib and lenvatinib. One of the main target molecules of m-TKIs is vascular endothelial growth factor receptor (VEGF-R). m-TKIs are known to cause adverse reactions such as hypertension and proteinuria as a class effect. Read More

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November 2018

Carence en iode pendant la grossesse.

Rev Prat 2016 Nov;67(9):998-1000

Service de gynécologieobstétrique, hôpital Beaujon, AP-HP, Clichy, France.

Iodine deficiency during pregnancy. Iodine is a necessary element to thyroid hormones synthesis, and is essential in neurological development. Iodine needs increases during pregnancy. Read More

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November 2016

Dietary vitamin and mineral intakes in a sample of pregnant women with either gestational diabetes or type 1 diabetes mellitus, assessed in comparison with Polish nutritional guidelines.

Ginekol Pol 2018 ;89(11):581-586

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland.

Objectives: Maintaining proper nutrition during pregnancy is crucial for pregnant women and especially for who have been diagnosed with type 1 diabetes mellitus (T1DM) or who develop gestational diabetes mellitus (GDM).

Material And Methods: To measure differences in vitamin and mineral intakes among women with normal pregnancies, pregnant women with GDM, and pregnant women with pre-gestational T1DM; and to assess the women's dietary intakes in comparison with Polish nutritional guidelines. The analysis was conducted among 83 pregnant women (29 GDM patients, 26 T1DM patients and 28 normal pregnancy participants) from whom we collected seven-day 24-hour dietary records during the second part of their pregnancies. Read More

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January 2018
1 Read

Value of CT spectral imaging in the differential diagnosis of thymoma and mediastinal lymphoma.

Br J Radiol 2018 Dec 3:20180598. Epub 2018 Dec 3.

1 Department of Radiology, Lanzhou University Second Hospital , Lanzhou , PR China.

Objective:: To investigate the imaging characteristics of thymoma and mediastinal lymphoma using spectral CT and evaluate whether the quantitative information can improve the differential diagnosis of these diseases.

Methods:: This retrospective study was approved by the institutional review board, and written informed consent was obtained from all patients. Overall, 39 patients with mediastinal tumors (24 thymomas and 15 mediastinal lymphomas) were examined with CT spectral imaging during the arterial phase (AP) and venous phase (VP). Read More

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December 2018

In vitro cytotoxicity evaluation of thiourea derivatives bearing Salix sp. constituent against HK-1 cell lines.

Nat Prod Res 2018 Dec 3:1-10. Epub 2018 Dec 3.

d School of Health Medical and Applied Sciences , Central Queensland University , Norman Gardens , Australia.

In searching for drugs from natural product scaffolds has gained interest among researchers. In this study, a series of twelve halogenated thiourea (ATX 1-12) via chemical modification of aspirin (a natural product derivative) and evaluated for cytotoxic activity against nasopharyngeal carcinoma (NPC) cell lines, HK-1 via MTS-based colorimetric assay. The cytotoxicity studies demonstrated that halogens at meta position of ATX showed promising activity against HK-1 cells (IC value ≤15 µM) in comparison to cisplatin, a positive cytotoxic drug (IC value =8. Read More

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December 2018
2 Reads

Are endocasts good proxies for brain size and shape in archosaurs throughout ontogeny?

J Anat 2018 Dec 3. Epub 2018 Dec 3.

Division of Paleontology, American Museum of Natural History, New York, NY, USA.

Cranial endocasts, or the internal molds of the braincase, are a crucial correlate for investigating the neuroanatomy of extinct vertebrates and tracking brain evolution through deep time. Nevertheless, the validity of such studies pivots on the reliability of endocasts as a proxy for brain morphology. Here, we employ micro-computed tomography imaging, including diffusible iodine-based contrast-enhanced CT, and a three-dimensional geometric morphometric framework to examine both size and shape differences between brains and endocasts of two exemplar archosaur taxa - the American alligator (Alligator mississippiensis) and the domestic chicken (Gallus gallus). Read More

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December 2018

Study of Percutaneous Stent Placement with Iodine-125 Seed Strand for Malignant Biliary Obstruction.

Cardiovasc Intervent Radiol 2018 Nov 30. Epub 2018 Nov 30.

Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Gulou District, Nanjing, 210029, China.

Purpose: To evaluate the effectiveness and safety of simultaneous placement of a self-expandable metallic stents (SEMS) and iodine-125 seed strand in the management of malignant obstructive jaundice (MOJ).

Materials And Methods: This study included 132 patients with MOJ treated from November 2015 to October 2017. Forty-five patients underwent insertion of SEMS with iodine-125 seed strands (Seeds group); the remaining 87 patients underwent SEMS placement alone (Control group). Read More

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November 2018

Current controversies and future directions in the diagnosis and management of differentiated thyroid cancers.

Gland Surg 2018 Oct;7(5):473-486

Department of Surgery, New York Presbyterian Hospital, Weill Cornell Medicine, New York, NY, USA.

Despite the development of novel diagnostic, surgical, and chemotherapeutic approaches to differentiated thyroid cancers (DTCs), the diagnosis and management of these tumors remains controversial. The most recent American Thyroid Association (ATA) guidelines, released in 2015, reflect a recent shift towards less aggressive management for patients with DTCs. However, many clinicians have expressed concern that more conservative management will put patients at risk for disease recurrence and metastasis. Read More

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October 2018

Efficacy of radioactive iodine treatment of graves' hyperthyroidism using a single calculated I dose.

Clin Diabetes Endocrinol 2018 28;4:20. Epub 2018 Nov 28.

1Nuclear Medicine/Radiology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-5028 USA.

Objective: To evaluate the success rate of therapeutic administration of a single calculated I activity for eliminating hyperthyroidism due to Graves' disease.

Methods And Materials: Patients with Graves' hyperthyroidism underwent pinhole thyroid imaging, 24-h radioactive iodine uptake (RAIU) measurements and clinical examination and received a calculated I activity of 0.2 mCi per estimated gram of thyroid tissue, adjusted for the 24-h RAIU. Read More

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November 2018

The assessment of radio-adaptive response in graves' hyperthyroidism patients following radioactive iodine uptake.

World J Nucl Med 2018 Oct-Dec;17(4):270-274

Department of Medical Physics Radiobiology and Radiation Protection, Babol University of Medical Sciences, Babol, Iran.

Low doses of radiation affect the response of cells to higher doses; this phenomenon is called radio-adaptive response, which leads to increased resistance to subsequent higher doses. We have investigated the adaptive response using 0.37 MBq priming dose of I-131 followed by 296-444 MBq challenging dose in peripheral human lymphocyte cells. Read More

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December 2018

Evaluation of the physical and biological dosimetry methods in iodine-131-treated patients.

World J Nucl Med 2018 Oct-Dec;17(4):253-260

Department of Nuclear Medicine, Kayseri Training and Research Hospital, 38010 Kayseri, Turkey.

The aim of the study was to compare physical and biological dosimetry methods in iodine-131 (I-131)-receiving patients. The present study comprised of 47 patients (mean age: 47.9 ± 15. Read More

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December 2018

Improved enhancement in CT angiography with reduced contrast media iodine concentrations at constant iodine dose.

Sci Rep 2018 Nov 30;8(1):17493. Epub 2018 Nov 30.

Departement of Radiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussels (UZ Brussel), Laarbeeklaan 101, 1090, Brussels, Belgium.

The study objective is to investigate the impact of a wide range of contrast media (CM) iodine concentrations on CT enhancement at constant total iodine dose (TID) and iodine delivery rate (IDR). Seven injection protocols, based on different iodine concentrations ranging from 120 to 370 mg I/mL, were assessed on 4 minipigs at a constant TID of 320 mg I/kg and IDR of 0.64 g I/s. Read More

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November 2018

Unravelling the role of vacancies in lead halide perovskite through electrical switching of photoluminescence.

Nat Commun 2018 Nov 30;9(1):5113. Epub 2018 Nov 30.

Institute of Advanced Materials (INAM), Universitat Jaume I, 12006, Castello, Spain.

We address the behavior in which a bias voltage can be used to switch on and off the photoluminescence of a planar film of methylammonium lead triiodide perovskite (MAPbI) semiconductor with lateral symmetric electrodes. It is observed that a dark region advances from the positive electrode at a slow velocity of order of 10 μm s. Here we explain the existence of the sharp front by a drift of ionic vacancies limited by local saturation, that induce defects and drastically reduce the radiative recombination rate in the film. Read More

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November 2018
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Long-term effects of radioiodine treatment on salivary gland function in adult survivors of pediatric differentiated thyroid carcinoma.

J Nucl Med 2018 Nov 30. Epub 2018 Nov 30.

Department of Endocrinology, University of Groningen, University Medical Center Groningen, Netherlands.

Pediatric differentiated thyroid cancer (DTC) is a rare disease. Initial treatment of DTC consists of a (near) total thyroidectomy and radioactive iodine (I) therapy. Previous studies in adults showed that I treatment may result in a reduced salivary gland function. Read More

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November 2018

Update on Strategies to Reduce Infectious Complications After Prostate Biopsy.

Eur Urol Focus 2018 Nov 29. Epub 2018 Nov 29.

Academic Department of Urology, CHRU Tours, François Rabelais University, Tours, France. Electronic address:

Context: Prostate biopsy is one of the most performed procedures in urology. As a diagnostic procedure it should be of low risk. However, morbidity following prostate biopsy is common due to infectious complications. Read More

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November 2018

Recurrence after low-dose radioiodine ablation and recombinant human thyroid-stimulating hormone for differentiated thyroid cancer (HiLo): long-term results of an open-label, non-inferiority randomised controlled trial.

Lancet Diabetes Endocrinol 2018 Nov 27. Epub 2018 Nov 27.

Cancer Research UK & UCL Cancer Trials Centre, UCL Cancer Institute, University College London, London, UK. Electronic address:

Background: Two large randomised trials of patients with well-differentiated thyroid cancer reported in 2012 (HiLo and ESTIMABL1) found similar post-ablation success rates at 6-9 months between a low administered radioactive iodine (I) dose (1·1 GBq) and the standard high dose (3·7 GBq). However, recurrence rates following radioactive iodine ablation have previously only been reported in observational studies, and recently in ESTIMABL1. We aimed to compare recurrence rates between radioactive iodine doses in HiLo. Read More

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November 2018

Meta-analysis Comparison of Bilateral Axillo-Breast Approach Robotic Thyroidectomy and Conventional Thyroidectomy.

Surg Innov 2018 Dec 3:1553350618817145. Epub 2018 Dec 3.

1 Department of Surgery, The Second Hospital of Shandong University, Jinan, Shandong, China.

Objective: Despite gaining popularity, bilateral axillo-breast approach robotic thyroidectomy (BABA RT) remains controversial. We performed a meta-analysis to evaluate the safety and effectiveness of BABA RT compared with open thyroidectomy (OT) in thyroid disease.

Methods: A literature search was conducted using various databases, including PubMed, Web of Science, and Cochrane Library, up to February 2018. Read More

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December 2018
2 Reads

Coulomb explosion imaging of CHI and CHClI photodissociation dynamics.

J Chem Phys 2018 Nov;149(20):204313

J. R. Macdonald Laboratory, Department of Physics, Kansas State University, Manhattan, Kansas 66506, USA.

The photodissociation dynamics of CHI and CHClI at 272 nm were investigated by time-resolved Coulomb explosion imaging, with an intense non-resonant 815 nm probe pulse. Fragment ion momenta over a wide / range were recorded simultaneously by coupling a velocity map imaging spectrometer with a pixel imaging mass spectrometry camera. For both molecules, delay-dependent pump-probe features were assigned to ultraviolet-induced carbon-iodine bond cleavage followed by Coulomb explosion. Read More

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November 2018

Synthesis of 2-Quinolinones via a Hypervalent Iodine(III)-Mediated Intramolecular Decarboxylative Heck-Type Reaction at Room Temperature.

Org Lett 2018 Dec 5. Epub 2018 Dec 5.

State Key Laboratory of Bioengineering Reactor, Shanghai Key Laboratory of New Drug Design, and School of Pharmacy , East China University of Science and Technology , Shanghai 200237 , P. R. China.

A hypervalent iodine(III)-mediated intramolecular decarboxylative Heck-type reaction of 2-vinyl-phenyl oxamic acids has been developed. The unique ring-strain-enabled radical decarboxylation mechanism is preliminarily revealed. This protocol features metal-free reaction conditions and operational simplicity, allowing the lactamization of 2-vinylanilines using a readily accessible carbonyl source and the synthesis of various 2-quinolinones with excellent chemoselectivity at room temperature. Read More

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December 2018

Recurrent goiters: risk factors, patient quality of life, and efficacy of radioiodine therapy.

Pol Arch Intern Med 2018 Dec 5. Epub 2018 Dec 5.

INTRODUCTION Goiter recurrence occurs in a substantial number of patients after thyroid resection. OBJECTIVES We aimed to investigate the prevalence and risk factors of recurrent goiters, influence of goiter recurrence on patient quality of life (QoL) and the efficacy of therapy with radioactive iodine (RAI). PATIENTS AND METHODS This was a case-control study. Read More

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December 2018

Iodized Salt Consumption and its Association with Intelligence Quotient (IQ) Among 6-12 years Age Group Children in Bihar.

Indian J Pediatr 2018 Dec 5. Epub 2018 Dec 5.

Department of Community Medicine, Patna Medical College, Patna, India.

Objectives: To estimate the proportion of households using adequately iodized salt, total goitre rate and intelligence quotient (IQ) and to assess association, if any, between consumption of iodized salt and intelligence quotient of children aged 6-12 y in the selected districts of Bihar.

Methods: Community based cross-sectional study was conducted in three districts of Bihar by using cluster sampling technique.

Results: Consumption of iodized salt was 73. Read More

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December 2018

Dual Energy Spectral CT Imaging in the assessment of Gastric Cancer and cell proliferation: A Preliminary Study.

Sci Rep 2018 Dec 4;8(1):17619. Epub 2018 Dec 4.

Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200127, China.

Gastric cancer is one of the main diseases leading to cancer-related death. The recently introduced dual-energy spectral CT (DEsCT), allows to obtain many quantitative measurements from iodine-based material decomposition (MD) images, which contribute to improve the accuracy of staging of GC comparing to multidetector spiral CT. And Ki-67 is a well-recognized nuclear antigen-specific biomarker reflecting cellular proliferation for estimating growth fractions of various tumor types. Read More

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December 2018
1 Read

Regional Cardiac Sympathetic Nervous System Evaluation Using 123I-mIBG SPECT in Patients with Heart Failure.

J Med Imaging Radiat Sci 2018 Dec 19;49(4):397-405. Epub 2018 Jun 19.

School of Dentistry & Health Sciences, Charles Sturt University, Wagga Wagga, Australia; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia; Cardiac Health Institute, Sydney, Australia.

Background: Heart failure (HF) involves both mechanical and autonomic nervous system dysfunction that can lead to sudden cardiac death. In the failing human heart, there is increased release of norepinephrine from neurons and reduced uptake. Iodine-123-labeled metaiodobenzylguanidine (123I-mIBG) demonstrates reduced global uptake and increased washout associated with increased mortality in HF. Read More

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December 2018

Inorganic Salts and Antimicrobial Photodynamic Therapy: Mechanistic Conundrums?

Molecules 2018 Dec 3;23(12). Epub 2018 Dec 3.

Laser Research Centre, Faculty of Health Science, University of Johannesburg, Johannesburg, Doornfontein 2028, South Africa.

We have recently discovered that the photodynamic action of many different photosensitizers (PSs) can be dramatically potentiated by addition of a solution containing a range of different inorganic salts. Most of these studies have centered around antimicrobial photodynamic inactivation that kills Gram-negative and Gram-positive bacteria in suspension. Addition of non-toxic water-soluble salts during illumination can kill up to six additional logs of bacterial cells (one million-fold improvement). Read More

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December 2018

Assessment of Dietary Iodine Intake in School Age Children: The Cross-Sectional ANIVA Study.

Nutrients 2018 Dec 3;10(12). Epub 2018 Dec 3.

Department of Preventive Medicine and Public Health, Food Sciences, Toxicology and Legal Medicine, School of Pharmacy, University of Valencia, Vicent Andres Estelles Avenue, Burjassot, 46100 Valencia, Spain.

Iodine deficiency is one of the most important health problems in the world. It intervenes in the synthesis of thyroid hormones, which carry out important functions, so that a deficit of this mineral causes alterations of different kinds such as those related to growth. The objective of the present study was to know the prevalence of iodine deficit in the diet of Valencian children from 6 to 8 years old and their relationship with anthropometry. Read More

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December 2018

Les traitements oraux par les inhibiteurs de kinase ont amélioré le pronostic.

Rev Prat 2017 Jun;67(6):685-688

pour le réseau Tumeurs rares INCa « TUTHYREF », service de médecine nucléaire et cancérologie endocrinienne, institut Gustave-Roussy, Villejuif, France.

Advanced thyroid cancer of follicular origin. Advanced thyroid cancer of follicular origin is infrequent. Treatment consists in levothyroxine, focal treatment modalities (surgery, external radiation beam therapy, thermal ablation) and radioactive iodine administration. Read More

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Les indications de l’iode 131 sont fondées sur les risques de maladie résiduelle et de rechute.

Rev Prat 2017 Jun;67(6):680-684

Département de cancérologie cervico-faciale, institut Gustave- Roussy et université Paris-Saclay, Villejuif, France.

Treatment of differentlated thyroid cancers. Surgery is the first - and sometimes the only - treatment of differentiated thyroid cancers. The main goal is to resect all macrospcopic disease with low permanent morbidity. Read More

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Response: Iodine Status in Filipino Women of Childbearing Age ( 2018;33:372-9, Michael E. Serafico et al.).

Endocrinol Metab (Seoul) 2018 Dec;33(4):495-496

Department of Science and Technology, Food and Nutrition Research Institute (DOST-FNRI), Taguig, Philippines.

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December 2018

Letter: Iodine Status in Filipino Women of Childbearing Age ( 2018;33:372-9, Michael E. Serafico et al.).

Authors:
Zheng Feei Ma

Endocrinol Metab (Seoul) 2018 Dec;33(4):493-494

Department of Health and Environmental Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, China.

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December 2018
2 Reads

Thyroid-Stimulating Hormone Reference Ranges in the First Trimester of Pregnancy in an Iodine-Sufficient Country.

Endocrinol Metab (Seoul) 2018 Dec;33(4):466-472

Department of Endocrinology, Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Chile.

Background: Thyroid dysfunction is associated with negative neonatal and obstetric outcomes. Large differences in thyroid function reference intervals exist across different populations. These differences can be explained by population-specific factors, such as iodine status. Read More

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December 2018
4 Reads

Thyroid-Stimulating Hormone Reference Ranges in Early Pregnancy: Possible Influence of Iodine Status.

Authors:
Tae Yong Kim

Endocrinol Metab (Seoul) 2018 Dec;33(4):445-446

Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

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December 2018

Potentiometric characterization of iodine-based disinfecting preparations.

J Pharm Biomed Anal 2018 Nov 24;165:90-93. Epub 2018 Nov 24.

Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria. Electronic address:

A potentiometric method is presented that allows to characterize aqueous iodine-based disinfecting solutions and preparations, respectively. By means of three electrodes (iodide-sensitive, platinum redox, and reference electrode), the concentrations of free iodine, iodide, and triiodide were determined. The apposition "free" means iodine not complexed with ligands originating from the organic matrix of the iodophoric iodine source (e. Read More

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November 2018
2 Reads

Copper-Catalyzed One-Pot Synthesis of 2-Arylthiochromenones: An in Situ Recycle of Waste Byproduct as Useful Reagent.

Org Lett 2018 Dec 4. Epub 2018 Dec 4.

Department of Chemistry , Indian Institute of Technology Madras , Chennai 600036 , Tamil Nadu , India.

Copper-catalyzed one-pot synthesis of various 2-arylthiochromenones is developed using xanthate as an odorless sulfur source from easily acquirable 2'-halochalcones. This methodology demonstrates that the cross-coupled product thiochromanone synthesized from 2'-halochalcones (upstream reaction) is oxidized to thiochromenone (downstream reaction) in the same pot using waste byproduct (KI) of the first step as powerful oxidant molecular iodine (I). This one-pot synthesis has been further extended for the synthesis of 3,3'-methylenebisthioflavone using dimethyl sulfoxide (DMSO) as solvent and methylene source. Read More

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December 2018
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Synthesis of Functionalized Monoaryl-λ³-iodanes via Chemo- and Site-selective ipso-Substitution Reactions.

Chemistry 2018 Dec 3. Epub 2018 Dec 3.

Hokkaido University, Faculty of Pharmaceutical Sciences, Kita-ku, Lab of Synthetic Organic Chemistry, 060-0812, Sapporo, JAPAN.

Monoaryl-λ³-iodanes are potentially attractive arylating agents. They are generally synthesized from aryl iodides via oxidation, which can cause functional group incompatibility, especially when polyfunctionalized derivatives are desired. Here we describe the direct synthesis of monoaryl-λ³-iodanes via a chemoselective ipso-substitution reaction of arylgermanes and arylstannanes with iodine tris(trifluoroacetate). Read More

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December 2018

Optimization of a dedicated protocol using a small-voxel PSF reconstruction for head-and-neck FDG PET/CT imaging in differentiated thyroid cancer.

EJNMMI Res 2018 Dec 3;8(1):104. Epub 2018 Dec 3.

INSERM 1086 ANTICIPE, Normandie University, Caen, France.

Background: FDG PET/CT is crucial before neck surgery for nodal recurrence localization in iodine-refractory differentiated or poorly differentiated thyroid cancer (DTC/PDTC). A dedicated head-and-neck (HN) acquisition performed with a thin matrix and point-spread-function (PSF) modelling in addition to the whole-body PET study has been shown to improve the detection of small cancer deposits. Different protocols have been reported with various acquisition times of HN PET/CT. Read More

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December 2018

The suitability of chili pepper ( L.) for alleviating human micronutrient dietary deficiencies: A review.

Food Sci Nutr 2018 Nov 8;6(8):2239-2251. Epub 2018 Oct 8.

Department of Botany Medicinal Plants and Economic Development (MPED) Research Centre University of Fort Hare Alice South Africa.

Human micronutrient dietary deficiency remains an enormous global problem and probably accounts for the cause of many chronic health conditions and diseases. Above two (2) billion individuals on the planet today have been estimated to be deficient in major minerals and vitamins, predominantly zinc, iodine, vitamin A, and iron primarily due to inadequate dietary intake. The eradication of deficiencies in micronutrient on a sustainable basis will be conceivable only when diets of vulnerable populace provide all required nutrients in adequate amounts. Read More

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November 2018

An Insight Into the Potentiation Effect of Potassium Iodide on aPDT Efficacy.

Front Microbiol 2018 19;9:2665. Epub 2018 Nov 19.

Department of Biology and CESAM, University of Aveiro, Aveiro, Portugal.

Antimicrobial photodynamic therapy (aPDT) is gaining a special importance as an effective approach against multidrug-resistant strains responsible of fatal infections. The addition of potassium iodide (KI), a non-toxic salt, is recognized to increase the aPDT efficiency of some photosensitizers (PSs) on a broad-spectrum of microorganisms. As the reported cases only refer positive aPDT potentiation results, in this work we selected a broad range of porphyrinic and non-porphyrinic PSs in order to gain a more comprehensive knowledge about this aPDT potentiation by KI. Read More

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November 2018
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An Unusual Case Report: Occurrence of Renal Cell Carcinoma, Basal Cell Carcinoma and Chronic Lymphocytic Leukemia in a Case of Papillary Thyroid Carcinoma Treated with Radioactive Iodine.

Iran J Med Sci 2018 Nov;43(6):659-663

Department of Hematology and Medical Oncology, Shiraz University of Medical Sciences, Shiraz, Iran.

The standard therapy for thyroid cancer is total or near total thyroidectomy, followed by the administration of radioactive iodine for remnant ablation or residual disease. Patients with radioiodine therapy are predisposed to second malignant neoplasms in organs such as central nervous system (CNS), breast, prostate, kidney, bone marrow, salivary gland, and digestive tract. Exposure to carcinogen including occupational and therapy related hazard, aging and genetic susceptibility are other causes of second primary cancers. Read More

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November 2018
1 Read

Quarter-millimeter spectral coronary stent imaging with photon-counting CT: Initial experience.

J Cardiovasc Comput Tomogr 2018 Nov - Dec;12(6):509-515. Epub 2018 Oct 15.

Radiology and Imaging Sciences - National Institutes of Health Clinical Center, Bethesda, MD, USA; Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA. Electronic address:

Purpose: To evaluate the performance and clinical feasibility of 0.25 mm resolution mode of a dual-energy photon-counting detector (PCD) computed tomography (CT) system for coronary stent imaging and to compare the results to state-of-the-art dual-energy energy-integrating detector (EID) CT.

Materials And Methods: Coronary stents with different diameters (2. Read More

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October 2018

Radiotherapy of prostate cancer in renal transplant recipients: single-center experience.

Neoplasma 2018 Sep 4. Epub 2018 Sep 4.

Department of Urology with Kidney Transplant Center, Comenius University Faculty of Medicine and University Hospital Bratislava, Bratislava, Slovakia.

This study analyzed the long-term outcomes of localized prostate cancer in renal transplant recipients after radiotherapy treatment - mainly brachytherapy. We retrospectively analyzed clinical data of renal transplant recipients between 2003 and 2016 at a single tertiary center, and identified four patients with high serum PSA level during regular follow-up, 1-108 months after primary renal transplantation. The mean age of patients with detected high serum PSA level with 9. Read More

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September 2018
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Profiles of genomic alterations in primary esophageal follicular dendritic cell sarcoma: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13413

The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing.

Rationale: Follicular dendritic cell (FDC) sarcoma is a rare tumor with FDC differentiation that typically arises within lymph nodes but can also occur extranodally. To date, the primary esophageal FDC sarcoma has not been reported in the English literature.

Patient Concerns: We described a 67-year-old female who foremostly presented with dysphagia, and the patient was readmitted due to a dry cough and pain of his right shoulder 2 years after initial treatment. Read More

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November 2018

Risk Factors and Maternal Morbidity Associated with Unintentional Hysterotomy Extension at the Time of Cesarean Delivery.

Am J Perinatol 2018 Nov 30. Epub 2018 Nov 30.

Department of Obstetrics and Gynecology, Washington University School of Medicine in St. Louis, St. Louis, Missouri.

Objective:  Our aim was to estimate the incidence of unintentional hysterotomy extension at the time of cesarean delivery and to identify associated risk factors and maternal morbidity.

Study Design:  We conducted a secondary analysis of a randomized controlled trial evaluating chlorhexidine-alcohol versus iodine-alcohol for skin antisepsis in women undergoing cesarean delivery. We included patients with a low transverse hysterotomy. Read More

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November 2018
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