5,732 results match your criteria Iodine Deficiency

Sea water desalination: A newly discovered cause of iodine deficiency.

Birth Defects Res 2018 Jun 19. Epub 2018 Jun 19.

Center for Epidemiology and Environmental Health (CEOH, LLC) Washington, District of Columbia.

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Reproducible and reliable general semiquantitative food frequency questionnaire for evaluating iodine intake in Chinese children.

Nutr Res 2018 Jul 22;55:72-80. Epub 2018 Apr 22.

School of Public Health, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin 300070, China. Electronic address:

Iodine deficiency is a global issue that is correlated with a variety of diseases and can affect individuals of all ages. We hypothesized that a general, semiquantitative food frequency questionnaire (FFQ) could be a valuable tool to evaluate iodine intake in children. Study participants comprised 687 healthy children between the ages of 7 and 13 years. Read More

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Georgian Med News 2018 May(278):103-107

West Kazakhstan Marat Ospanov State Medical University, Aktobe, Republic of Kazakhstan.

Aim of research - to study the iodine supply of the region according to the degree of urinary iodine excretion in the West region of the Republic of Kazakhstan. Of 6493 schoolchildren participating in the study of the frequency of goiter, random sampling was applied to select 884 children to determine UIC. To establish the excretion of inorganic iodine in a single portion of urine in the field, express diagnostics, the "Iodine test" kits (manufactured in Ukraine), was applied. Read More

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[Status of lactating women's iodine nutrition and thyroid function in different iodine nutrition level of children in Gansu Province].

Wei Sheng Yan Jiu 2018 Jan;47(1):56-61

Gansu Center for Disease Prevention and Control, Lanzhou 730020, China.

Objective: To assess the iodine nutrition and thyroid function of lactatingwomen in different iodine nutrition level of children in Gansu Province, and provide a scientific basis for iodine supplementation.

Methods: Liangzhou district( the median urinary iodine was greater than or equal to 300 g/L), Linze county( the median urinary iodine was from 200 to 299 g/L) and Huating county( the median urinary iodine was from100 to 199 g/L) were selected according to 8-10 years old children urinary iodine in2009. Huating county, Liangzhou district and Linze county were as iodine excessive area, iodine suitable area 1 and iodine suitable area 2, respectively in 2014. Read More

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January 2018
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[Effect factors of the prevalence of thyroid nodules in Zhejiang Province in 2010].

Wei Sheng Yan Jiu 2017 Nov;46(6):875-887

Environment and Occupational Health Department, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.

Objective: To assess the prevalence of thyroid nodules and explore the risk factors for thyroid nodules among the community residents in Zhejiang Province.

Methods: The residents of twenty-two communities in Zhejiang Province were selectedwith stratified cluster sampling. The cross-sectional survey includes questionnaire, examination on thyroid. Read More

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November 2017

[Follow-up study on diet, folic acid and iron status in 358 cases of Uighur pregnant women from Xinjiang Kashi].

Wei Sheng Yan Jiu 2017 Jul;46(4):563-568

Department of Nutrition And Food Hygiene, Public Health College, Xinjiang Medical University, Urumqi 830011, China.

Objective: To understand the dietary intake situation of Uighur pregnant women, investigate folic acid level and its influencing factors, to provide evidence for health education of maternal nutrition and implementation of proper nutrition, balanceddiet guidance.

Methods: 358 cases of Uighur trimester pregnant women for the study, took the method of 3 d 24 h dietary recall to survey their dietary and collect blood samples. The Hb was detected by the cyanide methemoglobinmethod. Read More

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Effect of maternal and neonatal factors on neonatal thyroid stimulating hormone: Results from a population-based prospective cohort study in China.

J Trace Elem Med Biol 2018 Sep 25;49:151-156. Epub 2018 May 25.

Department of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin, China. Electronic address:

Objective: Neonatal TSH screening is effective in detecting congenital hypothyroidism and estimating iodine status in a given population, but various factors influence TSH levels. The aim of this study was to evaluate the effect of maternal and neonatal factors on neonatal TSH levels.

Design And Setting: Data were obtained from an ongoing prospective cohort study. Read More

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September 2018

Iodine Deficiency in Zhejiang Pregnant Women in the Context of Universal Salt Iodization Programme.

Sci Rep 2018 Jun 11;8(1):8835. Epub 2018 Jun 11.

Zhejiang Provincial Center for Disease Control and Prevention, Department of Environmental and Occupational Health, Hangzhou, 310051, China.

Zhejiang introduced universal salt iodization (USI) programme in 1995 and has achieved the goal of elimination of iodine deficiency disorders (IDD) since 2011. However, no systematical data of iodine nutritional status in population in pregnancy is available. In this cross-sectional study, pregnant women were interviewed to complete questionnaires in addition to handing in samples of urine and household table salt between March 2016 to February 2017. Read More

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Maternal iodine supplementation improves motor coordination in offspring by modulating the mGluR1 signaling pathway in mild iodine deficiency-induced hypothyroxinemia rats.

J Nutr Biochem 2018 May 1;58:80-89. Epub 2018 May 1.

Department of Occupational and Environmental Health, School of Public Health, China Medical University, Shenyang, PR China. Electronic address:

Iodine is an essential component for thyroid hormone synthesis. Epidemiological investigations have demonstrated that maternal mild iodine deficiency (ID)-induced hypothyroxinemia can affect intellectual and behavioral function in offspring. There is no definitive evidence demonstrating the effects of maternal iodine supplementation on neurobehavioral function in regional areas with mild ID. Read More

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May 2018
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Urinary Iodine Concentrations and Mortality Among U.S. Adults.

Thyroid 2018 Jun 8. Epub 2018 Jun 8.

UCLA Fielding School of Public Health, Department of Epidemiology, Los Angeles, Colorado, United States ;

Background: Iodine deficiency has long been recognized as an important public health problem. Global approaches such as salt iodization that aim to overcome iodine deficiency have been successful. Meanwhile, they have led to excessive iodine consumption in some populations, thereby increasing the risks of iodine-induced thyroid dysfunction, as well as the comorbidities and mortality associated with hypothyroidism and hyperthyroidism. Read More

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Association of Iodine Deficiency With Hearing Impairment in US Adolescents Aged 12 to 19 Years: Analysis of NHANES 2007-2010 Data.

JAMA Otolaryngol Head Neck Surg 2018 Jun 7. Epub 2018 Jun 7.

Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, Georgia.

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Low iodine intake from dairy foods despite high milk iodine content in Israel.

Thyroid 2018 Jun 1. Epub 2018 Jun 1.

The Hebrew University of Jerusalem, The Institute of Biochemistry Food and Nutrition Science , Herzl Street , PO BOX 12 , Rehovot, Please Select, Israel , 76100 ;

Background: Milk is a major source of iodine in human nutrition. Because both iodine content and consumption of milk and dairy vary widely over time and populations, their contribution to iodine intake must be evaluated regularly. Our recent national iodine survey found Israel's population to be mild deficient, possibly due to unmonitored changes in food-content of dietary iodine. Read More

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Thyrotoxicosis after iodine fortification. A 21 year Danish population based study.

Clin Endocrinol (Oxf) 2018 May 31. Epub 2018 May 31.

Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark.

Objective: Monitoring the influence of cautious iodine fortification (IF) on the incidence rate of overt thyrotoxicosis in Denmark with formerly frequent multinodular toxic goitre.

Design: A 21 year (1997-2017) prospective population-based study identified all new cases of overt biochemical thyrotoxicosis in two open cohorts: a Western cohort with moderate iodine deficiency (ID) and an Eastern cohort with mild ID (total n=533,969 by January 1 , 1997). A diagnostic algorithm was applied to all thyroid function tests performed within the study areas. Read More

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Iodine in Human Milk: A Systematic Review.

Adv Nutr 2018 May;9(suppl_1):347S-357S

US Department of Agriculture, Agricultural Research Service, Western Human Nutrition Research Center, Davis, CA.

Because infants are born with small amounts of stored intrathyroidal iodine, they depend on human-milk iodine for normal physical and neurologic growth and development. The mammary gland concentrates iodide; however, there is a lack of consensus on the concentrations of breast-milk iodine necessary to achieve equilibrium in the infant. The objectives of the present review are to consider trends in breast-milk iodine concentrations over the course of lactation, to determine which maternal factors or interventions influence breast-milk iodine concentrations, to examine the association between breast-milk iodine concentrations and infant iodine status, and to identify how newer data contribute to the literature and inform recommendations for achieving optimal breast-milk iodine concentrations. Read More

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May 2018
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[Recovery rate in differentiated thyroid cancer. Experiences of one of the Hungarian clinical centers].

Orv Hetil 2018 Jun;159(22):878-884

Klinikai Központ, I. Belgyógyászati Klinika, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs, Ifjúság útja 13., 7624.

Introduction And Aim: The worldwide incidence of differentiated thyroid cancer (DTC) has markedly increased during the last few decades. According to the international guidelines, principles of DTC management are in transformation. The aim of our work was to evaluate patients' current likelihood of recovery. Read More

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Median urinary iodine concentration reflected sufficient iodine supply in neonates from Northeast Germany in 2005-2006.

Eur J Nutr 2018 May 25. Epub 2018 May 25.

Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Greifswald, Germany.

Purpose: Data from recent adult studies suggest a decline of median urinary iodine concentrations (UIC) in Germany, but since 1996 no German study investigated UIC in neonates. The aim of our study was to investigate UIC and serum thyroid-stimulating hormone (TSH) levels in neonates from Germany.

Methods: We used data from 399 neonates, which were born between April 2005 and November 2006 in the Northeast of Germany. Read More

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Effect of radioactive iodine-induced hypothyroidism on longitudinal bone growth during puberty in immature female rats.

Exp Anim 2018 May 22. Epub 2018 May 22.

Department of Obstetrics and Gynecology, College of Medicine, Hanyang University.

Thyroid cancer in children, the most common endocrine malignancy, shows aggressive behavior and has a high recurrence rate after surgical ablation. Radioactive iodine (RAI) treatment is the most effective primary modality for medical ablation of juvenile thyroid cancer, and leads to intentional hypothyroidism. Although several negative impacts of hypothyroidism have been reported in children in response to other antithyroid agents, the combined effects of RAI exposure and hypothyroidism, on growing bones specifically, are unknown. Read More

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Anthropometry-based 24-h urinary creatinine excretion reference for Chinese children.

PLoS One 2018 23;13(5):e0197672. Epub 2018 May 23.

The Department of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin, China.

To establish 24-h urinary creatinine excretion reference ranges based on anthropometry in healthy Chinese children, a cross-sectional survey was conducted using twice-sampled 24-h urine and anthropometric variables. Age- and sex-specific 24-h creatinine excretion reference ranges (crude and related to individual anthropometric variables) were derived. During October 2013 and May 2014, urine samples were collected. Read More

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Association between urinary sodium levels and iodine status in Korea.

Korean J Intern Med 2018 May 18. Epub 2018 May 18.

Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background/aims: To evaluate the association between the urinary sodium concentration and iodine status in different age groups in Korea.

Methods: This nationwide, population-based, cross-sectional study used data from the Korean National Health and Nutrition Examination Survey (VI 2-3, 2014 to 2015). We included 3,645 subjects aged 10 to 75 years with normal kidney function and without a history of thyroid disease. Read More

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May 2018
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Preconception Maternal Iodine Status Is Positively Associated with IQ but Not with Measures of Executive Function in Childhood.

J Nutr 2018 Jun;148(6):959-966

Medical Research Council (MRC) Lifecourse Epidemiology Unit.

Background: Adverse effects of severe maternal iodine deficiency in pregnancy on fetal brain development are well-established, but the effects of milder deficiency are uncertain. Most studies examine iodine status in pregnancy; less is known about iodine nutrition before conception.

Objective: We examined relations between maternal preconception iodine status and offspring cognitive function, within a prospective mother-offspring cohort. Read More

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June 2018
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Effects of Iodized Salt and Iodine Supplements on Prenatal and Postnatal Growth: A Systematic Review.

Adv Nutr 2018 May;9(3):219-237

Human Nutrition Laboratory, Institute of Food, Nutrition, and Health, ETH Zurich, Zurich, Switzerland.

Hypothyroidism due to iodine deficiency can impair physical development, most visibly in the marked stunting of myxedematous cretinism caused by severe in utero iodine deficiency. Whether iodine repletion improves growth in noncretinous children is uncertain. Therefore, the aim of our systematic review was to assess the effects of iodine fortification or supplementation on prenatal and postnatal growth outcomes in noncretinous children. Read More

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May 2018
2 Reads

Impact of Double-Fortified Salt with Iron and Iodine on Hemoglobin, Anemia, and Iron Deficiency Anemia: A Systematic Review and Meta-Analysis.

Adv Nutr 2018 May;9(3):207-218

Emory University, Nutrition and Health Science Program, Laney Graduate School.

Double-fortified salt (DFS) containing iron and iodine has been proposed as a feasible and cost-effective alternative for iron fortification in low- and middle-income countries (LMICs). We conducted a systematic review and meta-analysis from randomized and quasi-randomized controlled trials to 1) assess the effect of DFS on biomarkers of iron status and the risk of anemia and iron deficiency anemia (IDA) and 2) evaluate differential effects of DFS by study type (efficacy or effectiveness), population subgroups, iron formulation (ferrous sulfate, ferrous fumarate, and ferric pyrophosphate), iron concentration, duration of intervention, and study quality. A systematic search with the use of MEDLINE, EMBASE, Cochrane, Web of Science, and other sources identified 221 articles. Read More

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May 2018
2 Reads

Factors Affecting the Presence of Adequately Iodized Salt at Home in Wolaita, Southern Ethiopia: Community Based Study.

Int J Food Sci 2018 22;2018:4394908. Epub 2018 Mar 22.

College of Health Sciences and Medicine, Wolaita Sodo University, Sodo, Ethiopia.

Background: Universal use of iodized salt is a simple and inexpensive method to prevent and eliminate iodine deficiency disorders like mental retardation. However, little is known about the level of adequately iodized salt consumption in the study area. Therefore, the study was aimed at assessing the proportion of households having adequately iodized salt and associated factors in Wolaita Sodo town and its peripheries, Southern Ethiopia. Read More

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March 2018
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Urinary iodine concentration and thyroid volume of pregnant women attending antenatal care in two selected hospitals in Ashanti Region, Ghana: a comparative cross-sectional study.

BMC Pregnancy Childbirth 2018 May 15;18(1):166. Epub 2018 May 15.

Department of Sonography, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Background: Iodine deficiency is a major public health problem affecting people worldwide, particularly pregnant women. Iodine requirements increase substantially during pregnancy making pregnant women vulnerable to iodine deficiency and its disorders such as abortions, stillbirths and pregnancy goitre as well as congenital abnormalities, cretinism and mental retardation in their children. The primary aim of this study was to evaluate the prevalence of iodine deficiency and goitre among pregnant women attending antenatal sessions at two selected hospitals in Ashanti region, Ghana. Read More

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Disruption in Thyroid Signaling Pathway: A Mechanism for the Effect of Endocrine-Disrupting Chemicals on Child Neurodevelopment.

Front Endocrinol (Lausanne) 2018 30;9:204. Epub 2018 Apr 30.

Department of Pediatrics, New York University School of Medicine, New York, NY, United States.

Thyroid hormones are crucial in normal brain development. Transient and mild thyroid hormone insufficiency in pregnancy is also associated with impaired neurodevelopment in the offspring (e.g. Read More

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Transient Hypothyroidism During Lactation Arrests Myelination in the Anterior Commissure of Rats. A Magnetic Resonance Image and Electron Microscope Study.

Front Neuroanat 2018 27;12:31. Epub 2018 Apr 27.

Departamento de Histología y Anatomía, Facultad de Medicina, Universidad Miguel Hernández, Sant Joan d'Alacant, Alicante, Spain.

Thyroid hormone deficiency at early postnatal ages affects the cytoarchitecture and function of neocortical and telencephalic limbic areas, leading to impaired associative memory and in a wide spectrum of neurological and mental diseases. Neocortical areas project interhemispheric axons mostly through the corpus callosum and to a lesser extent through the anterior commissure (AC), while limbic areas mostly project through the AC and hippocampal commissures. Functional magnetic resonance data from children with late diagnosed congenital hypothyroidism and abnormal verbal memory processing, suggest altered ipsilateral and contralateral telencephalic connections. Read More

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Rapid Iodine Sensing on Mechanically Treated Carbon Nanofibers.

Sensors (Basel) 2018 May 9;18(5). Epub 2018 May 9.

Department of Mechanical and Aerospace Engineering, University of California, Irvine, CA 92697, USA.

In this work, we report on a rapid, efficient electrochemical iodine sensor based on mechanically treated carbon nanofiber (MCNF) electrodes. The electrode’s highly graphitic content, unique microstructure, and the presence of nitrogen heteroatoms in its atomic lattice contribute to increased heterogeneous electron transfer and improved kinetics compared to conventional pyrolytic carbons. The electrode demonstrates selectivity for iodide ions in the presence of both interfering agents and high salt concentrations. Read More

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Evaluation and Management of the Child with Hypothyroidism.

Recent Pat Endocr Metab Immune Drug Discov 2018 05 8. Epub 2018 May 8.

Departments of Medicine, Community Health Sciences, and Oncology, The University of Calgary, Calgary, Alberta. Canada.

Background: Thyroid hormones are critical for early neurocognitive development as well as growth and development throughout childhood. Prompt recognition and treatment of hypothyroidism is therefore of utmost importance to optimize physical and neurodevelopmental outcomes.

Objective: To review in depth the evaluation, diagnosis, and treatment of hypothyroidism in children. Read More

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Excessive Iodine Intake and Subclinical Hypothyroidism in Children and Adolescents Aged 6-19 Years: Results of the Sixth Korean National Health and Nutrition Examination Survey, 2013-2015.

Thyroid 2018 Jun;28(6):773-779

3 Department of Pediatrics, Seoul National University Bundang Hospital , Seongnam, Korea.

Background: Iodine is an important element for the synthesis of thyroid hormone, and its deficiency or excessive intake is associated with various thyroid diseases. Little is known about the association between iodine status and thyroid function among children and adolescents living in iodine-rich areas. Therefore, this study analyzed this association using data from a nationwide survey. Read More

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A Comparative Study of Iodized Salt Programs: Shanghai and Switzerland.

Biol Trace Elem Res 2018 May 5. Epub 2018 May 5.

Institute of Iodine Deficiency Disorders Prevention and Control, Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, China.

Both Shanghai and Switzerland are developed regions with long-standing salt iodization programs and periodic monitoring. However, the two regions have their own approach to the implementation of the iodized salt policy. In Shanghai, monitoring was carried out every few years, using probability-proportional-to-size sampling technique to select 30 sampling units. Read More

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May 2018
2 Reads

Contemporary challenges to iodine status and nutrition: the role of foods, dietary recommendations, fortification and supplementation.

Proc Nutr Soc 2018 Apr 29:1-12. Epub 2018 Apr 29.

Human Nutrition,School of Medicine,Dentistry and Nursing,College of Medical,Veterinary and Life Sciences,University of Glasgow,10-16 Alexandra Parade,Glasgow G31 2ER,UK.

Iodine deficiency (ID) in women of childbearing age remains a global public health concern, mainly through its impact on fetal and infant neurodevelopment. While iodine status is improving globally, ID is still prevalent in pregnancy, when requirements increase. More than 120 countries have implemented salt iodisation and food fortification, strategies that have been partially successful. Read More

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The assessment of iodine status - populations, individuals and limitations.

Ann Clin Biochem 2018 Jan 1:4563218774816. Epub 2018 Jan 1.

1 Chemical Pathology and Metabolic Medicine, Department of Laboratory Medicine, University Hospital Southampton, Southampton, UK.

Iodine deficiency is a significant global health concern, and the single greatest cause of preventable cognitive impairment. It is also a growing public health concern in the UK particularly among pregnant women. Biomarkers such as urinary iodine concentration have clear utility in epidemiological studies to investigate population-level iodine status, but determination of iodine status in individuals is much more problematic with current assays. Read More

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January 2018
1 Read

Iron deficiency is associated with Hypothyroxinemia and Hypotriiodothyroninemia in the Spanish general adult population: Di@bet.es study.

Sci Rep 2018 Apr 26;8(1):6571. Epub 2018 Apr 26.

Department of Endocrinology and Nutrition, Hospital Regional Universitario de Málaga, IBIMA, Málaga, Spain.

Previous studies have suggested that iron deficiency (ID) may impair thyroid hormone metabolism, however replication in wide samples of the general adult population has not been performed. We studied 3846 individuals free of thyroid disease, participants in a national, cross sectional, population based study representative of the Spanish adult population. Thyroid stimulating hormone (TSH), free thyroxin (FT4) and free triiodothyronine (FT3) were analyzed by electrochemiluminescence (E170, Roche Diagnostics). Read More

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High prevalence of iodine deficiency in pregnant women living in adequate iodine area.

Endocr Connect 2018 May 26;7(5):762-767. Epub 2018 Apr 26.

Thyroid UnitDivision of Endocrinology and Metabolism, Hospital das Clinicas HCFMUSP-Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil

Objectives: Iodine deficiency during pregnancy is associated with obstetric and neonatal adverse outcomes. Serum thyroglobulin (sTg) and thyroid volume (TV) are optional tools to urinary iodine concentration (UIC) for defining iodine status. This cross-sectional study aims to evaluate the iodine status of pregnant women living in iodine-adequate area by spot UIC and correlation with sTg, TV and thyroid function. Read More

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Iodine deficiency in pregnant women at first trimester in Ankara.

J Turk Ger Gynecol Assoc 2018 04 27. Epub 2018 Apr 27.

Ankara University School of Medicine, Department of Obstetrics and Gynecology, Ankara, Turkey.

Objective: Iodine deficiency in pregnant woman in Ankara was shown in previous studies. We aimed to conduct a study in a tertiary center to investigate for the need for iodine replacement in our population.

Material And Methods: This was a single tertiary center, non-interventional, retrospective, cross-sectional study. Read More

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April 2018
1 Read


Georgian Med News 2018 Mar(276):60-65

«I. Horbachevsky Ternopil State Medical University» Ukraine.

The aim of the study ‒ to investigate the changes of thyroid function and to reveal the relationship in between intracellular distribution of iodine in the blood with the severity of the course of pneumonia in children. We investigated 70 patients in age 6-14 years with moderate and severe CAP and 35 healthy children. The levels of free thyroxine (fT4), free triiodo-thyronine (fT3) and thyroid stimulating hormone, thyroid gland ultrasound and urinary iodine were estimated. Read More

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Review of Iodine Nutrition in Iranian Population in the Past Quarter of Century.

Int J Endocrinol Metab 2017 Oct 28;15(4):e57758. Epub 2017 Oct 28.

Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.

Context: Iodine deficiency is one of the most important health problems worldwide. The overall aim of this study was a narrative review of the past and present status of iodine nutrition in the Iranian population to gather and provide valuable background data in this field for future studies.

Evidence Acquisition: For this narrative literature review study, published internal (SID, Iran doc, Iran medex) and international (Web of knowledge, Pubmed, SCOPUS) source studies were searched using the following medical subject heading terms: Iodine, IDD (iodine deficiency disorders), UIC (urinary iodine concentration), Goiter, IQ (intelligence quotient), thyroid hormone, Iodine and pregnancy, Iodine and breast feeding, as well as Iodized salt, reporting the prevalence of iodine deficiency and iodine nutrition status of different target populations in Iran over 25 years, between 1988 - 2014, were assessed. Read More

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October 2017
1 Read

Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal.

Nutrients 2018 Apr 21;10(4). Epub 2018 Apr 21.

Iodine Global Network, Seattle, WA 98107, USA.

Single and multiple variable regression analyses were conducted using data from stratified, cluster sample design, iodine surveys in India, Ghana, and Senegal to identify factors associated with urinary iodine concentration (UIC) among women of reproductive age (WRA) at the national and sub-national level. Subjects were survey household respondents, typically WRA. For all three countries, UIC was significantly different ( < 0. Read More

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Follicular Thyroid Carcinoma in a Country of Endemic Iodine Deficiency (1994-2013).

J Thyroid Res 2018 25;2018:6516035. Epub 2018 Feb 25.

Department of Pathology, Korle-Bu Teaching Hospital, P.O. Box 77, Korle-Bu, Accra, Ghana.

Background: Follicular thyroid cancer (FTC) has historically been linked to iodine deficiency. Although Ghana is among the iodine deficient regions of the world, the proportions, trends, and the clinical features of FTCs have not been studied as a single disease entity. The aim of this study was to determine the relative frequencies, trends, and the clinicopathological characteristics of FTCs among all thyroid malignancies in our institution. Read More

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February 2018

Iodine status of pregnant women from a coastal Brazilian state after the reduction in recommended iodine concentration in table salt according to governmental requirements.

Nutrition 2018 Feb 14;53:109-114. Epub 2018 Feb 14.

Endocrinology Service, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address:

Objective: To evaluate iodine status among pregnant women from a coastal state after Brazilian governmental resolution reducing iodine concentrations in table salt. Secondarily, we correlated urinary iodine concentration (UIC) with thyroid volume and hormones.

Methods: Inductively coupled plasma mass spectrometry was used to assess UIC from 629 samples of 244 first trimester pregnant women. Read More

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February 2018
5 Reads

Iodine Deficiency in a Study Population of Norwegian Pregnant Women-Results from the Little in Norway Study (LiN).

Nutrients 2018 Apr 20;10(4). Epub 2018 Apr 20.

Institute of Marine Research (IMR), P.O. Box 1870 Nordnes, 5817 Bergen, Norway.

Iodine sufficiency is particularly important in pregnancy, where median urinary iodine concentration (UIC) in the range of 150⁻250 µg/L indicates adequate iodine status. The aims of this study were to determine UIC and assess if dietary and maternal characteristics influence the iodine status in pregnant Norwegian women. The study comprises a cross-sectional population-based prospective cohort of pregnant women (Little in Norway (LiN)). Read More

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Changes in trophoblasts gene expression in response to perchlorate exposition.

Toxicol In Vitro 2018 Aug 17;50:328-335. Epub 2018 Apr 17.

Ecology and Health Laboratory, Public Health Institute, Universidad Veracruzana, Av. Luís Castelazo Ayala W/N, Col. Industrial Animas, Xalapa, Veracruz ZC 41190, Mexico. Electronic address:

Contaminated water with chlorates is a public health problem associated with iodine deficiency. Epidemiological evidence shows that iodine deficiency is a risk factor for preeclampsia (PE). In this study we use human BeWo trophoblast cells exposed to perchlorate (KClO) and changes in gene expression were analyzed by microarrays, quantitative RT-PCR (qRT-PCR) and immunoblot. Read More

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August 2018
1 Read

Regression Analysis to Identify Factors Associated with Household Salt Iodine Content at the Sub-National Level in Bangladesh, India, Ghana and Senegal.

Nutrients 2018 Apr 19;10(4). Epub 2018 Apr 19.

Iodine Global Network, Seattle, WA 98107, USA.

Regression analyses of data from stratified, cluster sample, household iodine surveys in Bangladesh, India, Ghana and Senegal were conducted to identify factors associated with household access to adequately iodised salt. For all countries, in single variable analyses, household salt iodine was significantly different ( < 0.05) between strata (geographic areas with representative data, defined by survey design), and significantly higher ( < 0. Read More

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April 2018
2 Reads

Potassium iodate levels in processed edible salts available in retail shops throughout Kenya, 2013.

Public Health Nutr 2018 Apr 19:1-3. Epub 2018 Apr 19.

2Field Epidemiology and Laboratory Training Program,Ministry of Health,Nairobi,Kenya.

Objective: Iodine-deficiency disorders, due to insufficiency of iodine in the diet, are a global public health problem. The Kenyan Food, Drugs and Chemical Substances Act stipulates that processed retail-available edible salts contain 50-84 mg of potassium iodate (KIO3) per kilogram of salt. The present study determined the status of KIO3 levels in commercial salts, for public health action. Read More

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April 2018
3 Reads

Assessment of Iodine Nutritional Status of School-Age Children in Kolkata District of West Bengal State in Post-Iodation Scenario.

J Trop Pediatr 2018 Apr 6. Epub 2018 Apr 6.

To evaluate the state of iodine nutrition in post-iodation scenario, 3500 children were examined clinically for endemic goitre. Iodine and thiocyanate were measured in 240 urine samples; iodine content in 210 salt samples was measured. Total goitre prevalence was 6. Read More

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April 2018
1 Read

Universal Salt Iodization Provides Sufficient Dietary Iodine to Achieve Adequate Iodine Nutrition during the First 1000 Days: A Cross-Sectional Multicenter Study.

J Nutr 2018 Apr;148(4):587-598

Human Nutrition Laboratory, Institute of Food Nutrition and Health, ETH Zurich, Zurich, Switzerland.

Background: Dietary iodine requirements are high during pregnancy, lactation, and infancy, making women and infants vulnerable to iodine deficiency. Universal salt iodization (USI) has been remarkably successful for preventing iodine deficiency in the general population, but it is uncertain if USI provides adequate iodine intakes during the first 1000 d.

Objective: We set out to assess if USI provides sufficient dietary iodine to meet the iodine requirements and achieve adequate iodine nutrition in all vulnerable population groups. Read More

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April 2018
3 Reads

Iodine nutrition status and prevalence of abnormal TSH levels in schoolchildren aged 6-7 years in the autonomous community of the Basque Country.

Endocrinol Diabetes Nutr 2018 May 10;65(5):247-254. Epub 2018 Apr 10.

Servicio de Endocrinología y Nutrición, Hospital de Sant Joan Despí Moisès Broggi, Sant Joan Despí (Barcelona), España.

Introduction: An epidemiological study conducted between 1988 and 1992 showed iodine deficiency and endemic goiter in the schoolchildren of the autonomous community of the Basque Country.

Objectives: 1) To ascertain the iodine nutrition status of schoolchildren aged 6-7 years, and 2) to estimate the prevalence of abnormal TSH levels in capillary blood.

Population And Methods: The study was conducted on 497 schoolchildren selected by random sampling. Read More

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Role of iodine-containing multivitamins during pregnancy for children's brain function: protocol of an ongoing randomised controlled trial: the SWIDDICH study.

BMJ Open 2018 Apr 10;8(4):e019945. Epub 2018 Apr 10.

Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.

Introduction: Iodine is essential for normal brain development. Moderate and severe fetal iodine deficiency results in substantial to serious developmental delay in children. Mild iodine deficiency in pregnancy is associated with neurodevelopmental deficits in the offspring, but evidence from randomised trials is lacking. Read More

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April 2018
4 Reads

Education and micronutrient deficiencies: an ecological study exploring interactions between women's schooling and children's micronutrient status.

BMC Public Health 2018 Apr 10;18(1):470. Epub 2018 Apr 10.

Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, 02111, USA.

Background: Formal education can be a nutrition-sensitive intervention that supports the scale-up and impact of nutrition-specific actions. Maternal education has long been linked to child survival, growth, and development while adult earnings and nutrition are tied to years in school as a child. However, less is known about the relationship between maternal education and the micronutrient status of children, women and the general population. Read More

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April 2018
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How will South Africa's mandatory salt reduction policy affect its salt iodisation programme? A cross-sectional analysis from the WHO-SAGE Wave 2 Salt & Tobacco study.

BMJ Open 2018 Mar 30;8(3):e020404. Epub 2018 Mar 30.

WHO Multi-Country Studies Unit, World Health Organization (WHO), Geneva, Switzerland.

Objective: The WHO's global targets for non-communicable disease reduction recommend consumption of<5 g salt/day. In 2016, South Africa was the first country to legislate maximum salt levels in processed foods. South Africa's salt iodisation fortification programme has successfully addressed iodine deficiency but information is dated. Read More

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March 2018
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