6,167 results match your criteria Iodine Deficiency


Current iodine nutrition status in Poland (2017): is the Polish model of obligatory iodine prophylaxis able to eliminate iodine deficiency in the population?

Public Health Nutr 2020 Jun 1:1-11. Epub 2020 Jun 1.

Department of Endocrinology, Jagiellonian University Medical College, Kraków, Poland.

Objective: The monitoring of the populations' iodine status is an essential part of successful programmes of iodine deficiency elimination. The current study aimed at the evaluation of current iodine nutrition in school children, pregnant and lactating women as a marker of the effectiveness and sustainability of mandatory iodine prophylaxis in Poland.

Design: The following iodine nutrition indicators were used: urinary iodine concentration (UIC) (all participants) and serum thyroglobulin (pregnant and lactating women). Read More

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http://dx.doi.org/10.1017/S1368980020000403DOI Listing

Factors Associated with Urinary Iodine Concentration among Women of Reproductive Age, 20-49 Years Old, in Tanzania: A Population-Based Cross-Sectional Study.

Curr Dev Nutr 2020 May 29;4(5):nzaa079. Epub 2020 Apr 29.

Department of Nutritional Sciences, Penn State University, State College, PA, USA.

Background: Universal salt iodization (USI) is the most feasible and cost-effective, and equitable, approach to prevent iodine deficiency. Severe maternal iodine deficiency during pregnancy is associated with serious adverse gestational and birth outcomes.

Objectives: The aim was to assess iodine status and identify independent factors associated with urinary iodine concentration (UIC) among women of reproductive age in Tanzania. Read More

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http://dx.doi.org/10.1093/cdn/nzaa079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236838PMC

Assessment of Iodine Status in Iranian Students Aged 8-10 Years: Monitoring the National Program for the Prevention and Control of Iodine Deficiency Disorders in 2016.

Iran J Public Health 2020 Feb;49(2):377-385

Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical, Tehran, Iran.

Background: Iodine is a key element in the synthesis of thyroid hormones. The deficiency of the secretion of them will Reduce IQ, disturbance in the psychomotor growth and shortened height. Urinary iodine is a good indicator of iodine intake status. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231715PMC
February 2020

Standardized Map of Iodine Status in Europe.

Thyroid 2020 May 28. Epub 2020 May 28.

Ernst Moritz Arndt University, Institute for Community Medicine, Rathenaustr. 48, Greifswald, Germany, D-17487;

Background Knowledge about the population's iodine status is important, because it allows adjustment of iodine supply and prevention of iodine deficiency. The validity and comparability of iodine related population studies can be improved by standardization, which was one of the goals of the EUthyroid project. The aim of this study was to establish the first standardized map of iodine status in Europe by using standardized UIC data. Read More

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http://dx.doi.org/10.1089/thy.2019.0353DOI Listing

[Content of vitamins and mineral substancеs in enriched milk].

Vopr Pitan 2020;89(2):116-121. Epub 2020 Mar 16.

Kemerovo State University, 650000, Kemerovo, Russian Federation.

The enrichment of food products of industrial production in order to replenish vitamin and mineral deficiency is an actual trend in optimizing the diet of adults and children. Enriched milk as a healthy food is in constant demand. In this regard, monitoring the content of nutrients declared by the manufacturer in fortified milk and identification of its assortment is an important task. Read More

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http://dx.doi.org/10.24411/0042-8833-2020-10022DOI Listing

Estimating the Health and Economic Benefits of Universal Salt Iodization Programs to correct Iodine Deficiency Disorders.

Thyroid 2020 May 27. Epub 2020 May 27.

Swiss Federal Institute of Technology Zurich, LFV E19, Schmelzbergstrasse 7, ETH Zentrum, Zurich, Switzerland, 8092;

Background: There has been tremendous progress over the past twenty-five years to control iodine deficiency disorders (IDD) through universal salt iodization (USI). In 2019, using the median urinary iodine concentration (MUIC), only 19 countries in the world were still classified as iodine deficient; in contrast in 1993, using the Total Goiter Rate (TGR), 113 countries were classified as iodine deficient. However, few analyses have tried to quantify the global health and economic benefits of USI programs, and the shift from TGR to MUIC as the main indicator of IDD complicates assessment of progress. Read More

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http://dx.doi.org/10.1089/thy.2019.0719DOI Listing

Thr92Ala polymorphism in the type 2 deiodinase gene: an evolutionary perspective.

J Endocrinol Invest 2020 May 20. Epub 2020 May 20.

Department of Medical, Surgical and Neurological Sciences, University of Siena, Viale Bracci 16, 53100, Siena, Italy.

Purpose: In the past, a role of thyroid hormones in human evolution has been hypothesized. T3, the metabolically active form, derives from extrathyroidal conversion of T4 by deionidase 2 (D2) enzyme encoded by DIO2 gene. In thyroid-deficient patients, decreased levels of free T3 have been associated with the polymorphism rs225014 A/G in DIO2, which causes the substitution of Threonine with Alanine (p. Read More

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http://dx.doi.org/10.1007/s40618-020-01287-5DOI Listing

Reference Values of Thyroid Hormones During the First Trimester of Pregnancy in Valencian Community (Spain) and Their Relationship with Iodine Intake.

Nutrients 2020 May 15;12(5). Epub 2020 May 15.

SONEV Research Group. School of Medicine and Health Sciences. Catholic University of Valencia San Vicente Mártir. C/Quevedo nº 2, Valencia, 46001 Spain.

Thyroid hormones require special monitoring during the first trimester of gestation. Local reference values should be applied if available, especially in iodine-deficient areas, as generalized iodine supplementation is controversial. The aim of the present study was to establish thyroid stimulating hormone (TSH) and free thyroxine (FT4) reference values in the first trimester of gestation in the Valencian community (Spain) and relate them to iodine intake. Read More

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http://dx.doi.org/10.3390/nu12051433DOI Listing

High prevalence of TPO-Abs and subclinical hypothyroidism in iodine-sufficient pregnant women in Northern Algeria.

J Trace Elem Med Biol 2020 Apr 29;61:126533. Epub 2020 Apr 29.

Endocrinology Department, Public Hospital Etablishment IbnZiri, Bologhine, 16090 Algiers, Algeria.

Background: Iodine is a trace element whose adequate intakes are essential during gestation to promote the correct growth and development of the fetus. Historically, endemic goiter and cretinism affected northern regions of Algeria, and iodized salt was introduced in 1990. However, there has been no national study of iodine nutrition in Algeria since 1994. Read More

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http://dx.doi.org/10.1016/j.jtemb.2020.126533DOI Listing

Iodine nutritional status of pregnant women in an urban area of northern Taiwan in 2018.

PLoS One 2020 15;15(5):e0233162. Epub 2020 May 15.

Division of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Pregnant women are considered as one of the most vulnerable groups for iodine deficiency. The Nutrition and Health Survey in Taiwan 2013 revealed that the median urinary iodine concentration (UIC) of non-pregnant women of child-bearing age of 15-44 years was 124 μg/L, which was adequate in general, but insufficient according to pregnancy criteria. The aim of this study was to determine the iodine nutritional status of pregnant women in an urban area of Northern Taiwan. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233162PLOS

Spot urine iodine levels below the WHO recommendation are not related to impaired thyroid function in healthy children and adolescents.

Eur J Nutr 2020 May 11. Epub 2020 May 11.

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital, Leipzig, Germany.

Purpose: Iodine deficiency in childhood and adolescence may lead to later thyroid dysfunction, stunted growth and cognitive impairment. The World Health Organization (WHO) has issued recommended age-dependent urine iodine concentration targets, but a critical threshold beyond which clinical sequelae are to be expected remains undefined. Our study aimed to investigate spot urine iodine concentration in a typical Central European cohort of children and adolescents, and consider the implications of these values in regard to laboratory parameters for evaluating thyroid function. Read More

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http://dx.doi.org/10.1007/s00394-020-02268-3DOI Listing

Assessment of the iodine nutritional status among Chinese school-aged children.

Endocr Connect 2020 May;9(5):379-386

Chongqing Center for Disease Control and Prevention, Chongqing, People's Republic of China.

Objective: The remarkable success of iodine deficiency disorders (IDD) elimination in China has been achieved through a mandatory universal salt iodization (USI) program. The study aims to estimate the relationship between urinary iodine concentration (UIC) and iodine content in edible salt to assess the current iodine nutritional status of school aged children.

Methods: A total of 5565 students from 26 of 39 districts/counties in Chongqing participated in the study, UIC and iodine content in table salt were measured. Read More

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http://dx.doi.org/10.1530/EC-19-0568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219133PMC

Consequences of Iodine Deficiency and Excess in Pregnancy and Neonatal Outcomes: A Prospective Cohort Study in Rio de Janeiro, Brazil.

Thyroid 2020 May 2. Epub 2020 May 2.

Federal University of Rio de Janeiro, Medicine School, - Av Prof Rodolfo Rocco s/n ,Ilha do Fundão Rio de JaneiroCEP 21941-590, Rio de Janeiro, Rio de Janeiro, Brazil, 21941590;

Background: Insufficient or excessive iodine intake during gestation may compromise adaptive mechanisms in maternal thyroid function and lead to adverse pregnancy outcomes. In this context, we aimed to study the effects of maternal iodine status in the first and third trimesters of gestation on obstetric and neonatal outcomes in an iodine-sufficient population in Rio de Janeiro, Brazil.

Methods: A total of 214 pregnant women in the first trimester of gestation were enrolled and prospectively followed until delivery between 2014-2017. Read More

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http://dx.doi.org/10.1089/thy.2019.0462DOI Listing

Iodine deficiency in Israeli pregnant women - a time for action.

Authors:
John H Lazarus

Isr J Health Policy Res 2020 May 1;9(1):20. Epub 2020 May 1.

Clinical Endocrinology, Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, UK.

Iodine is an essential micronutrient for thyroid gland function. Iodine deficiency disorders are a spectrum of conditions affecting the fetus, child, adolescent and adult. Iodine requirements are increased in pregnancy in order that the fetus receives enough maternal thyroxine via transplacental passage. Read More

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http://dx.doi.org/10.1186/s13584-020-00382-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193697PMC

Iodide Transporters in the Endometrium: A Potential Diagnostic Marker for Women with Recurrent Pregnancy Failures.

Med Princ Pract 2020 Apr 30. Epub 2020 Apr 30.

Objective: The element Iodine is an essential nutrient utilized by the thyroid glands, and deficiency of this element has been linked to reproductive failures. Iodide transporters are also present in reproductive tissues and cells of embryonic origin such as the endometrium and trophoblasts, respectively. The aim of this study is to understand if levels of iodide transporters are linked to pregnancy outcomes. Read More

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http://dx.doi.org/10.1159/000508309DOI Listing

The relationships between thyroid-stimulating hormone and/or dopamine levels in peripheral blood and IQ in children with different urinary iodine concentrations.

Neurosci Lett 2020 Jun 25;729:134981. Epub 2020 Apr 25.

School of public health, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin 300070, PR China; Tianjin Municipal Bureau of Health Inspection, 94 Guizhou Road, Heping District, Tianjin 300070, PR China. Electronic address:

Environmental iodine deficiency or excess can lead to inappropriate iodine nutrition in the population. Little research has been performed to determine whether changes in thyroid-stimulating hormone (TSH) and/or dopamine (DA) concentrations in peripheral blood are involved in intellectual impairment caused by inappropriate iodine nutrition. 498 children aged 7-12 from areas with different water iodine concentrations were included in the study. Read More

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http://dx.doi.org/10.1016/j.neulet.2020.134981DOI Listing

Change over time in the iodine nutritional status of pregnant women from the Pamplona healthcare region.

Endocrinol Diabetes Nutr 2020 Apr 20. Epub 2020 Apr 20.

Servicio de Endocrinología y Nutrición, Complejo Hospitalario de Navarra, Pamplona (Navarra), España; Instituto de Investigación Sanitaria de Navarra (IdisNa), Pamplona (Navarra), España.

Introduction: Adequate iodine intake is essential during pregnancy. A previous study of pregnant women from the Pamplona healthcare region showed mild iodine deficiency (mean urinary iodine level, 125 mcg/L). This study was intended to ascertain the iodine intake of pregnant women in our region and to analyze the change over time in their iodine nutritional status. Read More

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http://dx.doi.org/10.1016/j.endinu.2019.12.006DOI Listing

Systematic review and meta-analysis of the effects of iodine supplementation on thyroid function and child neurodevelopment in mildly-to-moderately iodine-deficient pregnant women.

Am J Clin Nutr 2020 Apr 22. Epub 2020 Apr 22.

Department of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom.

Background: Mild-to-moderate iodine deficiency, particularly in pregnancy, is prevalent; this is of concern because observational studies have shown negative associations with child neurodevelopment. Although neither the benefits nor the safety of iodine supplementation in pregnancy in areas of mild-to-moderate deficiency are well researched, such supplementation is increasingly being recommended by health authorities in a number of countries.

Objectives: By reviewing the most recent published data on the effects of iodine supplementation in mildly-to-moderately deficient pregnant women on maternal and infant thyroid function and child cognition, we aimed to determine whether the evidence was sufficient to support recommendations in these areas. Read More

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http://dx.doi.org/10.1093/ajcn/nqaa071DOI Listing

Assessing Cassava Flour Consumption Impact on Iodine Nutritional Status in Schoolchildren from Public Schools in Brazil.

Biol Trace Elem Res 2020 Apr 19. Epub 2020 Apr 19.

Department of Bioregulation, Health & Science Institute, Federal University of Bahia, Avenida Reitor Miguel Calmon, S/N. Vale do Canela. Room 301,, Salvador, BA, 40110-102, Brazil.

Cassava (Manihot esculenta Crantz) is an important food source in many developing countries. This root contains cyanoglucosides, which can aggravate iodine deficiency disorders (IDDs). To analyze the impact of cassava flour consumption (CFC) on urinary iodine concentration (UIC) among schoolchildren from public schools in Bahia, Brazil. Read More

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http://dx.doi.org/10.1007/s12011-020-02144-5DOI Listing

Iodine Status of Brazilian School-Age Children: A National Cross-Sectional Survey.

Nutrients 2020 Apr 13;12(4). Epub 2020 Apr 13.

Ministry of Health, Zona Cívico-Administrativa, Brasília DF 70058900, Brazil.

Salt iodization is the main public health policy to prevent and control iodine deficiency disorders. The National Salt Iodization Impact Assessment Survey (PNAISAL) was conducted to measure iodine concentration among Brazilian schoolchildren. A survey including 6-14-year-old schoolchildren from public and private schools from all 26 Brazilian states and the Federal District was carried out in the biennia 2008-2009 and 2013-2014. Read More

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http://dx.doi.org/10.3390/nu12041077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230565PMC

Trace Mineral Intake and Deficiencies in Older Adults Living in the Community and Institutions: A Systematic Review.

Nutrients 2020 Apr 13;12(4). Epub 2020 Apr 13.

University of Nottingham, School of Biosciences, Division of Food, Nutrition and Dietetics, Sutton Bonington, Loughborough, Leicestershire LE12 5RD, UK.

The global population is ageing with many older adults suffering from age-related malnutrition, including micronutrient deficiencies. Adequate nutrient intake is vital to enable older adults to continue living independently and delay their institutionalisation, as well as to prevent deterioration of health status in those living in institutions. This systematic review investigated the insufficiency of trace minerals in older adults living independently and in institutions. Read More

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http://dx.doi.org/10.3390/nu12041072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230219PMC

[Iodine nutritional status and intake levels in adult from different water iodine content areas of Xinjiang Uygur Autonomous Region in 2017].

Wei Sheng Yan Jiu 2020 Jan;49(1):36-50

Institute for Endemic Disease Control and Prevention, Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi 830002, China.

Objective: To understand the iodine nutrition status of adults in Xinjiang Uygur Autonomous Region under the effective control of iodine deficiency disease.

Methods: Using stratified cluster random sampling method, in the district to determine water iodine median<10 μg/L and ≥10 μg/L of urban and rural areas, a total of 10 survey points, deals from the collecting water deals of extracting water iodine content detection. Adults over 18 years old were randomly selected from 30 households at each survey site to carry out a survey on dietary iodine intake, and the contents of dietary salt iodine and adult urine iodine were tested. Read More

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http://dx.doi.org/10.19813/j.cnki.weishengyanjiu.2020.01.006DOI Listing
January 2020

Statistical analysis of the impact of clusters on caries prevalence and intensity in children aged 6-7 with different somatic health statuses.

Wiad Lek 2020 ;73(3):434-440

Department of Paediatric Dentistry, State Higher Educational Establishment Uzhhorod National University, Uzhhorod, Ukraine.

Objective: The aim: Determining the influence of cluster factors on the emergence and progression of caries in first- and second-grade children is appropriate in terms of determining the most significant ones.

Patients And Methods: Materials and methods: The dental status of 73 children, residents of Uzhhorod, who study in the first grades of secondary schools, has been assessed, three groups have been singled (the control group 26 healthy children). The indices of essential micro- and macronutrients in the hair, saliva, serum and urine, as well as anxiety level have been determined and the statistical analysis has been performed. Read More

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Goitre Prevalence and Urinary Iodine Concentration in School-Aged Children in the Ashanti Region of Ghana.

Int J Endocrinol 2020 23;2020:3759786. Epub 2020 Mar 23.

Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Background: Iodine deficiency is a public health problem. The universal salt iodization (USI) program is the main, simple, and cost-effective intervention strategy to control iodine deficiency. The study examined the iodine status in school-aged children in Ashanti region, Ghana, using thyroid volumes along with urinary iodine concentrations, the methods recommended by the WHO/ICCIDD for monitoring the sustained impact of USI programs. Read More

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http://dx.doi.org/10.1155/2020/3759786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125487PMC
March 2020
1.515 Impact Factor

Determining the relationship between dietary iodine intake, urinary iodine excretion and thyroid functions in people with type 2 diabetes mellitus.

Arch Endocrinol Metab 2020 Apr 6. Epub 2020 Apr 6.

Ankara Yildirim Beyazit University, Faculty of Medicine, Department of Endocrinology and Metabolism, Ankara, Turkey.

Objective: Type 2 diabetes mellitus (T2DM) is a worldwide health problem, and medical nutrition therapy is essential for improving the quality of life of patients with type 2 diabetes. Salt restriction may lead to iodine deficiency in these patients. Moreover, type 2 diabetes can be an indirect reason for thyroid disorders. Read More

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http://dx.doi.org/10.20945/2359-3997000000233DOI Listing

Selenium deficiency risks in sub-Saharan African food systems and their geospatial linkages.

Proc Nutr Soc 2020 Apr 8:1-11. Epub 2020 Apr 8.

School of Biosciences, University of Nottingham, Bonington Campus, Loughborough, LeicestershireLE12 5RD, UK.

Selenium (Se) is an essential element for human health. However, our knowledge of the prevalence of Se deficiency is less than for other micronutrients of public health concern such as iodine, iron and zinc, especially in sub-Saharan Africa (SSA). Studies of food systems in SSA, in particular in Malawi, have revealed that human Se deficiency risks are widespread and influenced strongly by geography. Read More

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http://dx.doi.org/10.1017/S0029665120006904DOI Listing

Iodine Deficiency as Assessed by Neonatal TSH in a Sample of Mother-and-Newborn Pairs in Jiangsu Province, China.

Biol Trace Elem Res 2020 Apr 6. Epub 2020 Apr 6.

Department of Health and Environmental Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, Jiangsu Province, China.

China has eliminated iodine deficiency disorders since 2011 via the implementation of universal salt iodisation. Following this, a new revised salt iodisation policy was introduced to reduce iodine content in table salt. Since maternal iodine deficiency can lead to cognitive impairment and cretinism in infants, the aim of our study was to assess if the iodine status of pregnant women and neonates was affected by the introduction of new salt iodisation policy. Read More

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http://dx.doi.org/10.1007/s12011-020-02135-6DOI Listing
April 2020
1.748 Impact Factor

The association between iodine intake and semen quality among fertile men in China.

BMC Public Health 2020 Apr 6;20(1):461. Epub 2020 Apr 6.

National Research Institute for Family Planning, Beijing, 100081, China.

Background: Iodine intake is essential in the production of thyroid hormone but very few foods are rich in it. Iodine deficiency or excess iodine level may both lead to thyroid disorders, which further affects human fertility function. The objective of this study is to investigate the relationship between iodine intake and seminal parameters among fertile men in China. Read More

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http://dx.doi.org/10.1186/s12889-020-08547-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137216PMC

Reference Intervals of the Ratio of Urine Iodine to Creatinine in Pregnant Women in an Iodine-Replete Area of China.

Biol Trace Elem Res 2020 Apr 5. Epub 2020 Apr 5.

Department of Endocrinology and Metabolism and the Institute of Endocrinology, The First Hospital of China Medical University, Shenyang, 110001, Liaoning, People's Republic of China.

The assessment method of iodine nutrition for pregnant women lacks strong evidence-based medicine. The prevalence of iodine deficiency in pregnant women may be overestimated using urinary iodine concentration (UIC). The reference intervals of UIC-to-urinary creatinine concentration ratio (UIC/UCr) were established using a self-sequential longitudinal study of pregnant women with singleton gestation who were recruited using the criteria of the National Academy of Clinical Biochemistry in Dandong City, which is a long-term iodine-replete area. Read More

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http://dx.doi.org/10.1007/s12011-020-02133-8DOI Listing

Appropriate Range of Median Urinary Iodine Concentration in 8- to 10-Year-Old Children Based on Generalized Additive Model.

Thyroid 2020 May 12. Epub 2020 May 12.

Institute of Iodine Deficiency Disorders, Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, China.

The appropriate range of median urinary iodine concentration (MUI) in children has always been controversial. To prevent the occurrence of a goiter epidemic in Shanghai, we explored the appropriate range of MUI by integrating multiple monitoring results. This study summarized and analyzed the monitoring data from 1997, 1999, 2011, 2014, and 2017 of children living in Shanghai. Read More

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http://dx.doi.org/10.1089/thy.2019.0813DOI Listing

Thyroglobulin can be a functional biomarker of iodine deficiency, thyroid nodules, and goiter in Chinese pregnant women.

Asia Pac J Clin Nutr 2020 ;29(1):27-34

The Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China. Email:

Background And Objectives: Thyroglobulin (Tg) is considered a sensitive indicator of iodine status for children and adults, but its usefulness for pregnant women is unknown. The aim of this study was attempting to explore the relationship between Tg and iodine status and the association between elevated Tg and thyroid diseases.

Methods And Study Design: A total of 2163 pregnant women were recruited in this study. Read More

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http://dx.doi.org/10.6133/apjcn.202003_29(1).0004DOI Listing
January 2020
1.360 Impact Factor

Low intake of iodized salt and iodine containing supplements among pregnant women with apparently insufficient iodine status - time to change policy?

Isr J Health Policy Res 2020 03 30;9(1). Epub 2020 Mar 30.

Obstetrics and Gynecology Department, "Barzilai" University Medical Center Ashkelon, Ashkelon, Israel.

Background: Iodine is an essential nutrient for human health throughout the life cycle, especially during early stages of intrauterine life and infancy, to ensure adequate neurocognitive development. The growing global reliance on desalinated iodine-diluted water raises the specter of increased iodine deficiency in several regions. The case of Israel may be instructive for exploring the link between iodine status and habitual iodine intake in the setting of extensive national reliance on desalinated water. Read More

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http://dx.doi.org/10.1186/s13584-020-00367-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104484PMC

Maternal serum perfluoroalkyl substance mixtures and thyroid hormone concentrations in maternal and cord sera: The HOME Study.

Environ Res 2020 Jun 16;185:109395. Epub 2020 Mar 16.

Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA. Electronic address:

Background: Per- and polyfluoroalkyl substances (PFAS) are ubiquitous. Previous studies have found associations between PFAS and thyroid hormones in maternal and cord sera, but the results are inconsistent. To further address this research question, we used mixture modeling to assess the associations with individual PFAS, interactions among PFAS chemicals, and the overall mixture. Read More

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http://dx.doi.org/10.1016/j.envres.2020.109395DOI Listing

Trend of Iodine Status in the Eastern Mediterranean Region and Impact of the Universal Salt Iodization Programs: a Narrative Review.

Biol Trace Elem Res 2020 Mar 27. Epub 2020 Mar 27.

Department of Nutrition Sciences, University of Vienna, UZA2 Althantstrasse 14, 1090, Vienna, Austria.

Recognizing the importance of iodine deficiency as a single most important preventable cause of brain damage, World Health Organization (WHO) urged all countries to scale up salt iodization since 1991 where iodine deficiency was declared as a global public health problem. All countries committed to report on the national iodine status of school-aged children (6-12 years), every 3 years. This paper aims to evaluate the progress of countries in Eastern Mediterranean Region (EMR) toward the eradication of iodine deficiency disorders (IDD) and recommend operational action to support implementation of the WHO Regional Nutrition Strategy (2020-2030). Read More

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http://dx.doi.org/10.1007/s12011-020-02083-1DOI Listing
March 2020
1.748 Impact Factor

Prevalence of anemia among elderly persons residing in old age homes in national capital territory, Delhi, India.

Indian J Public Health 2019 Oct-Dec;63(4):288-292

Department of Community Medicine, Lady Hardinge Medical College, New Delhi, India.

Background: Anemia is a common morbidity in elderly persons (aged 60 years or above). In India, in recent years, the number of old age homes (OAHs) and the residents living in them has increased significantly.

Objective: The aim of this study was to estimate the prevalence of anemia among elderly persons living in OAHs. Read More

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http://dx.doi.org/10.4103/ijph.IJPH_412_18DOI Listing

Maternal and neonatal outcomes and determinants of iodine deficiency in third trimester of pregnancy in an iodine sufficient area.

BMC Pregnancy Childbirth 2020 Mar 18;20(1):174. Epub 2020 Mar 18.

Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.

Background: Mild to moderate iodine deficiency in pregnant women may expose them to the increased risk of the development of goiter and thyroid disorder. There is a relationship between low maternal UIC (Urinary iodine concentration) in pregnancy and diminished placental weight and neonatal head circumference. The current study was an attempt to assess iodine nutritional status, its determinants and relationship with maternal and neonatal outcomes. Read More

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http://dx.doi.org/10.1186/s12884-020-02863-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079485PMC

U-Shaped Associations Between Urinary Iodine Concentration and the Prevalence of Metabolic Disorders: A Cross-Sectional Study.

Thyroid 2020 Apr 27. Epub 2020 Apr 27.

Department of Endocrinology and Metabolism and the Institute of Endocrinology, The First Hospital of China Medical University, Shenyang, Liaoning, P.R. China.

Iodine is important in both thyroid function and human metabolism. Studies have explored the effect of iodine on metabolic disorders through thyroid function. This study aimed to investigate the relationship between iodine status and metabolic disorders, such as metabolic syndrome (MetS), hypertension, impaired glucose metabolism, central obesity, and dyslipidemia. Read More

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http://dx.doi.org/10.1089/thy.2019.0516DOI Listing
April 2020
4.493 Impact Factor

Effects of an Iodine-Containing Prenatal Multiple Micronutrient on Maternal and Infant Iodine Status and Thyroid Function: A Randomized Trial in The Gambia.

Thyroid 2020 Apr 28. Epub 2020 Apr 28.

Department of Women and Children's Health, King's College London, London, United Kingdom.

Iodine supplementation is recommended to pregnant women in iodine-deficient populations, but the impact in moderate iodine deficiency is uncertain. We assessed the effect of an iodine-containing prenatal multiple micronutrient (MMN) supplement in a rural Gambian population at risk of moderate iodine deficiency. This study uses data and samples collected as a part of the randomized controlled trial Early Nutrition and Immune Development (ENID; ISRCTN49285450) conducted in Keneba, The Gambia. Read More

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http://dx.doi.org/10.1089/thy.2019.0789DOI Listing

A Case of the Forgotten Thyroid: The Sequelae of Chronic Untreated Hypothyroidism.

Cureus 2019 Mar 12;11(3):e4240. Epub 2019 Mar 12.

Family Medicine, University of Central Florida College of Medicine, Orlando, USA.

Hypothyroidism is a common endocrine disorder frequently caused by iodine deficiency, autoimmune disease, or as a result of certain medical treatments such as radioactive iodine. We report a 57-year-old woman 21 years pos-radioiodine ablation therapy for Graves' disease. She presented to the clinic after more than two decades without medical care with a variety of symptoms, including a left-sided lower facial droop and gait instability, and was found to have bradycardia, hyperlipidemia, and mild depression. Read More

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http://dx.doi.org/10.7759/cureus.4240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053559PMC

Maternal Iodine Status During Pregnancy Is Not Consistently Associated with Attention-Deficit Hyperactivity Disorder or Autistic Traits in Children.

J Nutr 2020 Mar 14. Epub 2020 Mar 14.

Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre-Sophia Children's Hospital, Rotterdam, Netherlands.

Background: Severe iodine deficiency during pregnancy can cause intellectual disability, presumably through inadequate placental transfer of maternal thyroid hormone to the fetus. The association between mild-to-moderate iodine deficiency and child neurodevelopmental problems is not well understood.

Objectives: We investigated the association of maternal iodine status during pregnancy with child attention-deficit hyperactivity disorder (ADHD) and autistic traits. Read More

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http://dx.doi.org/10.1093/jn/nxaa051DOI Listing

Comparison of the Effectiveness of Universal and Targeted Iodine Supplementation in Pregnant Women: A Randomized Controlled Trial.

Gynecol Obstet Invest 2020 11;85(2):189-195. Epub 2020 Mar 11.

Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand,

Objective: To compare the effectiveness of universal and targeted iodine supplementation strategies.

Methods: A randomized controlled trial involving low-risk Thai pregnant women was carried out. The participants were categorized into either the study group, in which iodine supplementation was varied based on median urine iodine concentration, or the control group, which received universal supplementation. Read More

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http://dx.doi.org/10.1159/000506800DOI Listing

The Results of 16 Years Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey

Authors:
Zheng Feei Ma

J Clin Res Pediatr Endocrinol 2020 Mar 11. Epub 2020 Mar 11.

Department of Health and Environmental Sciences, Xi’an Jiaotong-Liverpool University, Suzhou, China

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http://dx.doi.org/10.4274/jcrpe.galenos.2020.2020.0036DOI Listing

Iodine level concentration, coverage of adequately iodized salt consumption and factors affecting proper iodized salt utilization among households in North Ethiopia: a community based cross sectional study.

BMC Nutr 2019 18;5:28. Epub 2019 Apr 18.

2School of Public Health, Mekelle University, Ethiopia, Mekelle, Ethiopia.

Introduction: Adequate iodine fortified salt is the most common and effective method of preventing iodine deficiency. Studies showed households using iodized salt (15 Parts Per Million (PPM) to 80 PPM) of iodine at household level were low in Tigray region and other regions of Ethiopia. Limited studies have conducted on utilization of iodized salt at the household level and none of them did not addressed on factors affecting to proper iodized salt utilization. Read More

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http://dx.doi.org/10.1186/s40795-019-0291-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050811PMC

Knowledge about iodine requirements during pregnancy and breastfeeding among pregnant women living in Northern Ireland.

BMC Nutr 2019 12;5:24. Epub 2019 Mar 12.

1Regional Centre for Endocrinology and Diabetes, Royal Victoria Hospital Belfast, Belfast, UK.

Background: Iodine is an essential micronutrient important for foetal nerve and brain development, especially in the early stages of pregnancy. The re-emergence of mild to moderate iodine deficiency has recently been reported in the United Kingdom (UK). The level of knowledge amongst pregnant women regarding iodine nutrition is poorly understood. Read More

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http://dx.doi.org/10.1186/s40795-019-0285-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050819PMC

Prevalence of goiter and its associated factors among primary school children in Chole District, Arsi Zone, Ethiopia: a cross- sectional study.

BMC Nutr 2019 1;5. Epub 2019 Feb 1.

2Department of Public Health, St Paul's Hospital Millennium Medical College, P.O. Box, 1271 Addis Ababa, Ethiopia.

Background: Goiter remains one of the major public health problems particularly among young children in economically disadvantaged countries like Ethiopia. The aim of the study was to assess the prevalence of goiter and its associated factors among children aged 6-12 years in Chole district, Arsi Zone, Eastern Ethiopia.

Methods: A school based cross-sectional study was conducted in February, 2017 among 422 primary school children in Chole district, eastern Ethiopia. Read More

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http://dx.doi.org/10.1186/s40795-018-0267-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050880PMC
February 2019

Mild to Moderate Iodine Deficiency and Inadequate Iodine Intake in Lactating Women in the Inland Area of Norway.

Nutrients 2020 Feb 27;12(3). Epub 2020 Feb 27.

Department of Nursing and Health Promotion, Faculty of Health Sciences, OsloMet-Oslo Metropolitan University, 0130 Oslo, Norway.

Breastfed infants are dependent on an adequate supply of iodine in human milk for the production of thyroid hormones, necessary for development of the brain. Despite the importance of iodine for infant health, data on Norwegian lactating women are scarce. We measured iodine intake and evaluated iodine status and iodine knowledge among lactating women. Read More

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http://dx.doi.org/10.3390/nu12030630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146631PMC
February 2020

A Review of Published Literature Regarding Health Issues of Coastal Communities in Sabah, Malaysia.

Int J Environ Res Public Health 2020 02 27;17(5). Epub 2020 Feb 27.

Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.

Several of the coastal zones in Sabah, Malaysia, are isolated and inaccessible. This study aimed to review the published literature on the health status of the coastal communities in Sabah. The following four main health issues were found: (i) malaria, (ii) tuberculosis (TB), (iii) seafood poisoning, and (iv) antenatal problems. Read More

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http://dx.doi.org/10.3390/ijerph17051533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084212PMC
February 2020
2.063 Impact Factor

Graves' disease: Epidemiology, genetic and environmental risk factors and viruses.

Best Pract Res Clin Endocrinol Metab 2020 Jan 4;34(1):101387. Epub 2020 Feb 4.

Department of Translational Research of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy. Electronic address:

Graves' disease (GD) is the most common cause of hyperthyroidism in developed Countries. It is more common between 30 and 60 years; 5-10 times more frequent in women. The genetic predisposition accounts for 79% of the risk for GD, while environmental factors for 21%. Read More

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http://dx.doi.org/10.1016/j.beem.2020.101387DOI Listing
January 2020

Household Coverage with Adequately Iodized Salt and Iodine Status of Nonpregnant and Pregnant Women in Uzbekistan.

Thyroid 2020 Mar 26. Epub 2020 Mar 26.

GroundWork, Fläsch, Switzerland.

Globally, iodine deficiency has been drastically reduced since the introduction of salt iodization programs; nonetheless, many populations remain at-risk for iodine deficiency. This study aimed to assess the iodine status among women of reproductive age in Uzbekistan and to identify factors associated with iodine deficiency, including the availability of adequately iodized salt at the household level. A cross-sectional household survey was conducted to produce region-specific estimates of the household coverage with adequately iodized salt and iodine status among women for each of the 14 regions in Uzbekistan. Read More

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http://dx.doi.org/10.1089/thy.2019.0788DOI Listing

Food-based indicators are related to iron and iodine deficiencies of mother-toddler dyads during the lean season in northern Ghana.

Br J Nutr 2020 Feb 24:1-10. Epub 2020 Feb 24.

Food Science and Human Nutrition Department, Michigan State University, East Lansing, MI48824, USA.

Fe and iodine deficiencies are among the common forms of nutritional deficiencies globally and cause detrimental effects on mother and child. In developing countries, strategies to address these problems rarely use preventative dietary approaches. This cross-sectional study aims to ascertain whether dietary diversity score (DDS) and dietary patterns (DP) can predict the associated risk (AR) of Fe and iodine deficiencies in mother-toddler dyads during the dry/lean season in northern Ghana. Read More

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http://dx.doi.org/10.1017/S0007114520000604DOI Listing
February 2020