Search our Database of Scientific Publications and Authors

I’m looking for a

    5457 results match your criteria Iodine Deficiency

    1 OF 110

    An Increase in Consuming Adequately Iodized Salt May Not Be Enough to Rectify Iodine Deficiency in Pregnancy in an Iodine-Sufficient Area of China.
    Int J Environ Res Public Health 2017 Feb 20;14(2). Epub 2017 Feb 20.
    Department of Environmental and Occupational Health, Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, China.
    Universal salt iodization (USI) has been implemented for two decades in China. It is crucial to periodically monitor iodine status in the most vulnerable population, such as pregnant women. A cross-sectional study was carried out in an evidence-proved iodine-sufficient province to evaluate iodine intake in pregnancy. Read More

    Breast Milk Iodine Concentration Is a More Accurate Biomarker of Iodine Status Than Urinary Iodine Concentration in Exclusively Breastfeeding Women.
    J Nutr 2017 Feb 22. Epub 2017 Feb 22.
    Human Nutrition Laboratory, Institute of Food, Nutrition and Health, ETH Zurich, Zurich, Switzerland.
    Background: Iodine status in populations is usually assessed by the median urinary iodine concentration (UIC). However, iodine is also excreted in breast milk during lactation; thus, breast milk iodine concentration (BMIC) may be a promising biomarker of iodine nutrition in lactating women. Whether the mammary gland can vary fractional uptake of circulating iodine in response to changes in dietary intake is unclear. Read More

    Iodine deficiency status in the WHO Eastern Mediterranean Region: a systematic review.
    Environ Geochem Health 2017 Feb 21. Epub 2017 Feb 21.
    Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Iodine deficiency is a global public health issue because iodine plays a major role in the thyroid hormone synthesis and is essential for normal neurological development. This review summarizes the publications on iodine status in the WHO Eastern Mediterranean Region (EMR) countries. All related studies available in main national and international databases were systematically searched using some specific keywords to find article published between 1909 and 2015. Read More

    Reliability of thyroglobulin in serum compared with urinary iodine when assessing individual and population iodine nutrition status.
    Br J Nutr 2017 Feb 22:1-9. Epub 2017 Feb 22.
    1Arctic Health Research Centre,Institute of Clinical Medicine,Aalborg University Hospital,9000 Aalborg,Denmark.
    The occurrence of thyroid disorders relies on I nutrition and monitoring of all populations is recommended. Measuring I in urine is standard but thyroglobulin in serum is an alternative. This led us to assess the reliability of studies using serum thyroglobulin compared with urinary I to assess the I nutrition level and calculate the number of participants needed in a study with repeated data sampling in the same individuals for 1 year. Read More

    [Long-term effect of iodine deficiency on growth and food utilization rate in second filial generation rats].
    Zhonghua Yu Fang Yi Xue Za Zhi 2017 Feb;51(2):165-171
    Institute of Nutrition and Food Safety, School of Public Health, Lanzhou University, Lanzhou 730000, China.
    Objective: To study the effect of iodine deficiency on body weight, food consumption, and food utilization rate of second filial generation Wistar rats. Methods: According to the food pattern of a high-iodine deficient population, two types of low-iodine food have been produced using the main crops grown in this area (iodine levels of 50 and 20 μg/kg, respectively). Wistar rats were randomly divided into three groups, normal iodine group (NI group), low-iodine group one (LI group) and low-iodine group two (LII group), using the random number table method and fed diets containing 300, 50, and 20 μg/kg of iodine, respectively. Read More

    Improving iodine nutritional status and increasing prevalence of autoimmune thyroiditis in children.
    Indian J Endocrinol Metab 2017 Jan-Feb;21(1):85-89
    Department of Pediatrics, CSI Hospital, Bengaluru, Karnataka, India.
    Objective: The objective of this study is to evaluate the link between excess iodine intake as evidenced by increased urinary iodine excretion (UIE) and autoimmune thyroiditis in children and to assess the correlation between UIE and thyroid microsomal antibody (thyroid peroxidase [TPO]) titers in children.

    Materials And Methods: All children with goiter between age group 6 and 12 years, were subjected to blood tests for free thyroxine, thyroid stimulating hormone, and TPO antibody, fine needle aspiration was advised for all children with goiter. Forty-three children with confirmed autoimmune thyroiditis served as cases, and 43 children with euthyroid goiter with workup negative for autoimmune thyroiditis and iodine deficiency were enrolled as controls. Read More

    Factors affecting sustainable iodine deficiency elimination in Pakistan: A global perspective.
    J Epidemiol 2017 Feb 16. Epub 2017 Feb 16.
    Institute for Community Medicine, Walther-Rathenau Str. 48, Ernst Moritz Arndt University, D-17475, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site, University Greifswald, Germany.
    Iodine deficiency remains a considerable challenge worldwide, even after decades of efforts to address the problem. The aim of this review is to present the current situation in historically iodine-deficient Pakistan regarding iodine nutritional status and place it in a global perspective. We collected relevant articles from online bibliographic databases and websites of concerned organizations that addressed prevalence of goiter/iodine deficiency and barriers to sustainable control. Read More

    Urinary iodine in early pregnancy is associated with subclinical hypothyroidism in Tianjin, China: an observational study.
    BMC Endocr Disord 2017 Feb 17;17(1):10. Epub 2017 Feb 17.
    Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, No154 Anshan Road, Heping District, Tianjin, 300052, China.
    Background: Subclinical hypothyroidism (SH) is associated with adverse obstetric outcomes and neurodevelopment disorders. Both iodine deficiency and excess are associated with SH; however, few data regarding iodine nutrition status of pregnant women with SH are available. This study aimed to clarify whether iodine deficiency or excess is associated with SH, especially, when test results for anti-thyroid autoantibodies are negative. Read More

    Moderate-to-Severe Iodine Deficiency in the "First 1000 Days" Causes More Thyroid Hypofunction in Infants than in Pregnant or Lactating Women.
    J Nutr 2017 Feb 15. Epub 2017 Feb 15.
    Laboratory of Human Nutrition, Institute of Food, Nutrition and Health, Swiss Federal Institute of Technology (ETH), Zurich, Switzerland;
    Background: Iodine deficiency early in the life cycle-the "first 1000 days"-can cause hypothyroidism and irreversibly impair neuromotor development. However, the relative vulnerability among women and infants during this critical period is unclear, making it difficult for country-based programs with limited resources to prioritize their iodine interventions.Objective: Our aim was to determine the prevalence of thyroid hypofunction in women and infants living in an area of moderate-to-severe iodine deficiency. Read More

    Thyroid status of iodine deficient newborn infants living in central region of Turkey: a pilot study.
    World J Pediatr 2017 Feb 14. Epub 2017 Feb 14.
    Division of Neonatology, Department of Pediatrics, Erciyes University Medical Faculty, Talas Street, Kayseri, Turkey.
    Background: Iodine deficiency (ID) during the fetal and neonatal periods can lead to neonatal hypothyroidism. This study was conducted to evaluate the effect of ID on the thyroid hormone level of newborns living in Turkey.

    Methods: Between 1998 and 2013, 71 newborns with a urinary iodine concentration <100 μg/L were recruited into the study. Read More

    Low Iodine in the Follicular Lumen Caused by Cytoplasm Mis-localization of Sodium Iodide Symporter may Induce Nodular Goiter.
    Biol Trace Elem Res 2017 Feb 12. Epub 2017 Feb 12.
    Department of Endocrinology, The Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Quanzhou, Fujian, 362000, People's Republic of China.
    Iodine is a key ingredient in the synthesis of thyroid hormones and also a major factor in the regulation of thyroid function. A local reduction of iodine content in follicular lumen leads to overexpression of local thyroid-stimulating hormone receptor (TSHr), which in turn excessively stimulates the regional thyroid tissue, and result in the formation of nodular goiter. In this study, we investigated the relationship between iodine content and sodium iodide symporter (NIS) expression by using the clinical specimens from patients with nodular goiter and explored the pathogenesis triggered by iodine deficiency in nodular goiter. Read More

    Elimination of iodine deficiency disorders from the Americas: a public health triumph.
    Lancet Diabetes Endocrinol 2017 Jan 31. Epub 2017 Jan 31.
    Laboratory of Human Nutrition, ETH Zürich CH-8092, Switzerland; The Iodine Global Network, Ottawa, ON, Canada. Electronic address:

    The relationship between iron level and thyroid function during the first trimester of pregnancy: A cross-sectional study in Wuxi, China.
    J Trace Elem Med Biol 2017 Jan 22. Epub 2017 Jan 22.
    Clinical laboratory, Wuxi Maternity and Child Health Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu, China.
    Our objective was to evaluate the relationship between iron level and thyroid function during the first trimester of pregnancy in Eastern China. This was a hospital-based, cross-sectional observational study. A total of 1764 pregnant women were enrolled during their first trimester of gestation in Wuxi city. Read More

    Prevalence of thyroid disorders in elderly people in Germany. A screening study in a country with endemic goitre.
    Nuklearmedizin 2017 Feb 26;56(1):9-13. Epub 2017 Jan 26.
    Prof. Dr. Markus Luster, University Hospital Marburg, Department of Nuclear Medicine, Baldingerstraße, 35043 Marburg Tel: +49-6421-5862815, Fax: +49-6421-5867025, E-Mail:
    Aim: In a screening study on people of working age the prevalence of morphological thyroid disorders was 33.1 %. It is not known precisely whether this further increases after retirement. Read More

    The Role Of The World Health Organization In Eliminating Iodine Deficiency Worldwide.
    Recent Pat Endocr Metab Immune Drug Discov 2017 Jan 18. Epub 2017 Jan 18.
    WHO Regional Office for Europe UN City, Marmorvej 51 DK - 2100 Copenhagen, Denmark.
    Background: Iodine deficiency has been one of the most prevalent micronutrient deficiencies in the world, causing many health disorders, particularly in pregnant women and children. Despite increased salt iodization in some countries and regions, the process has lacked global coordination and sustainability, two prerequisites for reaching the aim of eliminating iodine deficiency. This goal can be reached only by evidence-based, effectively monitored joint and committed actions of all countries. Read More

    Role Of Iodine In Metabolism.
    Recent Pat Endocr Metab Immune Drug Discov 2017 Jan 19. Epub 2017 Jan 19.
    Chair and Department of Endocrinology, Jagiellonian University Collegium Medicum 31-501 Krakow, 17 Kopernika St., Poland.
    The natural resources of iodine are seawater, seaweeds and saltpeter-nitrate deposits in Chile. Over 1/3 of the global population is exposed to iodine deficiency, especially in the mountains. Iodine is a component of the thyroid hormones and a strong antioxidant with electric potential of -0. Read More

    Monitoring the effects of iodine prophylaxis in the adult population of southern Italy with deficient and sufficient iodine intake levels: a cross-sectional, epidemiological study.
    Br J Nutr 2017 Jan 18;117(1):170-175. Epub 2017 Jan 18.
    1Department of Pharmacy, Health and Nutritional Sciences,University of Calabria,87036 Arcavacata di Rende (CS),Italy.
    I prophylaxis is the most effective strategy to eradicate I deficiency disorders, but it has been shown to affect the thyroid disease pattern. In this study, we assessed the frequency of thyroid disorders in an adult population living in two areas of southern Italy after implementing I prophylaxis. To this aim, a cross-sectional, population-based study including 489 subjects from an I-deficient rural and an I-sufficient urban area of southern Italy was conducted. Read More

    Historical aspects of iodine deficiency control.
    Minerva Med 2017 Apr 12;108(2):124-135. Epub 2017 Jan 12.
    Erasme Hospital, Unit of Nuclear Medicine, Free University of Bruxelles-ULB, Bruxelles, Belgium.
    In 1895, iodine was characterized as an essential element of thyroid tissue by Baumann. The efficacy of iodine to prevent goiter was demonstrated by Marine in Northern USA in 1916-1920. Severe endemic goiter and cretinism had been almost entirely eliminated from continental Western Europe and Northern America before the 1930's; however large populations elsewhere and even some places in Western Europe (Sicily) were still affected up to the 2000's. Read More

    The way forward in Italy for iodine.
    Minerva Med 2017 Apr 12;108(2):159-168. Epub 2017 Jan 12.
    Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
    Italy is dealing with iodine deficiency since ancient times. In 1848 an ad hoc committee appointed by the king of Sardinia, identified extensive areas afflicted by endemic goiter and endemic cretinism in Piedmont, Liguria and Sardinia. Since then many epidemiological studies have been conducted in our country. Read More

    Iodine nutritional status and thyroid effects of exposure to ethylenebisdithiocarbamates.
    Environ Res 2017 Jan 7;154:152-159. Epub 2017 Jan 7.
    Department of Cell Biology and Neuroscience, Italian National Institute of Health, Viale Regina Elena 299, 00161 Rome, Italy. Electronic address:
    Introduction: Italy is still characterized by a mild iodine deficiency and is among the most intensive users of chemical products for agriculture in Europe. The aim of this study was i) to evaluate thyroid effects of exposure to mancozeb, a fungicide widely used in agriculture, in a sample of Italian grapevine workers, and ii) to verify whether the iodine intake may modulate the risk of thyroid disruption due to the mancozeb metabolite ethylenthiourea (ETU).

    Methods: One hundred seventy-seven occupationally exposed male workers (29 from Chianti, a mild iodine deficient area, and 148 from Bolzano an iodine sufficient province) and 74 non-occupationally exposed male controls (34 from Chianti and 40 from Bolzano) were enrolled in the study. Read More

    No Association between Elevated Thyroid-Stimulating Hormone at Birth and Parent-Reported Problem Behavior at Preschool Age.
    Front Endocrinol (Lausanne) 2016 19;7:161. Epub 2016 Dec 19.
    Unit of Public Health and Surveillance, Scientific Institute of Public Health , Brussels , Belgium.
    Objectives: Mild level of iodine deficiency during pregnancy may reduce maternal thyroid hormone production and supply to the fetus hence affecting brain neurodevelopment. The aim of the present study was to investigate the association between elevated neonatal thyroid-stimulating hormone (TSH) level (>5 mU/L), used as a marker of maternal mild iodine deficiency during late pregnancy, and behavioral development of preschool children.

    Methods: This retrospective cohort study included 310 Belgian mothers and their children aged 4-5 years old with TSH levels in the range of 0. Read More

    Poor dietary diversity, wealth status and use of un-iodized salt are associated with goiter among school children: a cross-sectional study in Ethiopia.
    BMC Public Health 2017 Jan 7;17(1):44. Epub 2017 Jan 7.
    Department of Human Nutrition, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, P.O. Box: 196, Gondar, Ethiopia.
    Background: Globally, more than two billion people are at risk of iodine deficiency disorders, 32% of which are school children. Iodine deficiency has been recognized as a severe public health concern in Ethiopia, however little is known about the problem. Therefore, this study aimed to assess the prevalence of goiter and associated factors among school children (6 to 12 years) in Dabat District, northwest Ethiopia. Read More

    Adequacy Assessment of a Universal Salt Iodization Program Two Decades after Its Implementation: A National Cross-Sectional Study of Iodine Status among School-Age Children in Tunisia.
    Nutrients 2016 Dec 25;9(1). Epub 2016 Dec 25.
    INNTA (National Institute of Nutrition and Food Technology), SURVEN (Nutrition Surveillance and Epidemiology in Tunisia) Research Laboratory, 11 Rue Jebel Lakhdar, babSaadoun, Tunis 1007, Tunisia.
    In the framework of a worldwide policy to eliminate iodine deficiency (ID) disorders, universal salt iodization was adopted in Tunisia two decades ago. The present study aims to evaluate this strategy, using both performance and impact indicators. A total of 1560 children, aged 6-12 years, were randomly sampled using a national, two-stage, stratified, cross-sectional cluster survey in 2012. Read More

    Knowledge and Perception of Consumption of Iodized Salt Among Food Handlers in Southern Ethiopia.
    Food Nutr Bull 2016 Jan 1:379572116684909. Epub 2016 Jan 1.
    2 Wolaita Sodo University, WolaitaSodo, Ethiopia.
    Background: Iodine deficiency is the world's single most important cause of preventable mental retardation. In Ethiopia, the knowledge and perception of food handlers toward the iodized salt consumption (ISC) was very low.

    Objective: To assess knowledge and perception of food handlers toward consumption of iodized salt in Wolaita Sodo town and Sodo Zuria woreda, 2014. Read More

    Larger Thyroid Volume and Adequate Iodine Nutrition in Chinese Schoolchildren: Local Normative Reference Values Compared with WHO/IGN.
    Int J Endocrinol 2016 24;2016:8079704. Epub 2016 Nov 24.
    Department of Environment and Occupational Health, Zhejiang Provincial Center for Disease Prevention and Control, Hangzhou, Zhejiang, China.
    Objective. Thyroid volume measured by ultrasound to define goiter needs reliable local thyroid volume reference from iodine-sufficient populations. The aim of this study is to explore the reference interval for normal thyroid volume in schoolchildren aged 8-10 years from Zhejiang Province, China. Read More

    Iodine deficiency and nutrition in Scandinavia.
    Minerva Med 2017 Apr 20;108(2):147-158. Epub 2016 Dec 20.
    Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden -
    Iodine nutrition is a result of geological conditions, iodine fortification and monitoring strategies within a country together with the dietary habits of the population. This review summarizes the basis for the current iodine situation in the Scandinavian countries in order to identify gaps in knowledge, determine necessary future steps, highlight landmarks in Scandinavian iodine research and consider ongoing studies in Scandinavian countries with high international impact. Historically, iodine deficiency disorders such as goiter were common in Norway and Sweden, but not in Denmark. Read More

    The changing phenotype of iodine deficiency disorders: a review of thirty-five years of research in north-eastern Sicily.
    Ann Ist Super Sanita 2016 Oct-Dec;52(4):550-557
    Dipartimento di Medicina Clinica e Sperimentale, Università di Messina, Messina, Italy.
    Iodine deficiency disorders (IDD) still represent a major public health problem, with almost 30% of the world population being exposed to the consequences of nutritional iodine deficiency (ID). In Italy, despite a sustained policy of iodine prophylaxis, more than 10% of people is still affected with goiter, and a presumably higher rate of subjects may suffer from minor cognitive deficits due to inadequate iodine supply during antenatal life. This review of systematic observational studies carried out over thirty-five years (1980-2015) in a sentinel ID area in North-eastern Sicily highlights the changing phenotypes of IDD in this region. Read More

    Environmental water chemistry and possible correlation with Kaschin-Beck Disease (KBD) in northwestern Sichuan, China.
    Environ Int 2017 Feb 18;99:282-292. Epub 2016 Dec 18.
    College of Earth Sciences, Chengdu University of Technology, 1 Erxianqiao 3rd Street E., Chengdu, Sichuan 610059, China.
    During the past several decades, etiological and geochemical studies tend to link the Kaschin-Beck Disease (KBD) to the deficiency of some specific trace elements (e.g., selenium and iodine) in the environment; however the link has been proven inconclusive. Read More

    Iodine status of pregnant women in South Australia after mandatory iodine fortification of bread and the recommendation for iodine supplementation.
    Matern Child Nutr 2016 Dec 16. Epub 2016 Dec 16.
    Women's and Children's Health Research Institute, North Adelaide, South Australia, Australia.
    Mandatory iodine fortification of bread was introduced in 2009 in Australia in response to the reemergence of iodine deficiency. The aim of this study was to assess iodine intake, urinary iodine concentration (UIC) and their correlation in pregnant women (n = 783) recruited from South Australia 2 years following mandatory iodine fortification. Total iodine intake (food and supplements) and UIC were assessed at study entry (<20 weeks') and at 28 weeks' gestation. Read More

    Nutrition situation in Latin America and the Caribbean: current scenario, past trends, and data gaps.
    Rev Panam Salud Publica 2016 Aug;40(2):104-113
    Micronutrient Initiative, Ottawa, Ontario, Canada.
    Objective: To determine the current nutritional status in Latin America and the Caribbean (LAC) and identify data gaps and trends in nutrition surveillance.

    Methods: A systematic Internet search was conducted to identify official sources that allowed for monitoring of LAC countries' nutritional status, including progress toward World Health Organization Global Nutrition Targets 2025. Reports from national nutrition surveillance systems and reports on nationally representative surveys were collected and collated to 1) analyze nutritional status, based on life-course anthropometric indicators and biomarkers, and 2) identify gaps in data availability and trends in nutritional deficiencies. Read More

    Urinary iodine concentration identifies pregnant women as iodine deficient yet school-aged children as iodine sufficient in rural Niger.
    Public Health Nutr 2016 Dec 15:1-8. Epub 2016 Dec 15.
    1Program in International and Community Nutrition,Department of Nutrition,University of California,Davis,One Shields Avenue,Davis,CA 95616,USA.
    Objective: To assess iodine status among pregnant women in rural Zinder, Niger and to compare their status with the iodine status of school-aged children from the same households.

    Design: Seventy-three villages in the catchment area of sixteen health centres were randomly selected to participate in the cross-sectional survey.

    Setting: Salt iodization is mandatory in Niger, requiring 20-60 ppm iodine at the retail level. Read More

    Epidemiology of iodine deficiency.
    Minerva Med 2017 Apr 14;108(2):116-123. Epub 2016 Dec 14.
    Consultant Physician and Endocrinologist, The Physicians' Clinic, London, UK -
    Iodine is an essential component of the thyroid hormones thyroxine (T4) and triiodothyronine (T3) produced by the thyroid gland. Iodine deficiency impairs thyroid hormone production and has adverse effects throughout life, particularly early in life as it impairs cognition and growth. Iodine deficiency remains a significant problem despite major national and international efforts to increase iodine intake, primarily through the voluntary or mandatory iodization of salt. Read More

    Endocrinology Update: Thyroid Disorders.
    FP Essent 2016 Dec;451:11-16
    University of Michigan Medical School Briarwood Family Medicine, 1801 Briarwood Circle, Ann Arbor, MI 48108.
    Thyroid disease affects nearly every organ system in the body. Hypothyroidism is a state of thyroid hormone insufficiency that results in decreased metabolism and secondary effects including fatigue and weight gain. Primary hypothyroidism typically is a result of autoimmune thyroiditis or iodine deficiency and is assessed by measurement of the thyroid-stimulating hormone (TSH) level. Read More

    [The iodine intake in a female population of an Apennine valley (Italy) in years 2003-2013].
    Epidemiol Prev 2016 Nov-Dec;40(6):414-417
    Zona distretto casentino, AUSL 8, Arezzo.
    Objectives: to assess if the iodine intake of pregnant women had increased or not after the introduction of Law no. 55 of March 2005 («Provisions aimed at the prevention of endemic goitre and other diseases from iodine deficiency») and if it reached the levels recommended by the World Health Organisation (WHO).

    Design: evaluation of ioduria values in the female local population enrolled. Read More

    Low magnesium diet alters distribution of macroelements and trace elements in tissues and organs of female rats.
    J Trace Elem Med Biol 2017 Jan 12;39:36-42. Epub 2016 Jul 12.
    Russian Society of Trace Elements in Medicine, 46 Zemlyanoy Val str., Moscow 105064, Russia; Trace Element-Institute for UNESCO, 7 rue Guillaume Paradin, 69008 Lyon, France.
    The aim of the present study was to assess whether dietary magnesium deficiency can alter distribution of macroelements and trace elements in different organs and tissues. Experiments were carried out on 12 adult female Wistar rats, which were fed either a diet with low Mg content (≤20mgkg(-1) of diet) (LMgD) or a diet with daily recommended Mg content (≈500mgkg(-1)) as control group (CG) for 70 days. On the 70th day of the experiment heart, aorta, femoral skeletal muscle, forebrain, cerebellum, pituitary gland, thyroid gland, ovaries, uterus, liver, kidneys, and spleen were taken for analysis of mineral content. Read More

    More than two-thirds of dietary iodine in children in northern Ghana is obtained from bouillon cubes containing iodized salt.
    Public Health Nutr 2016 Dec 1:1-7. Epub 2016 Dec 1.
    2Human Nutrition Laboratory,Institute of Food Science and Nutrition, Swiss Federal Institute of Technology,LFVD20,Schmelzbergstrasse 7,CH-8092 Zurich,Switzerland.
    Objective: Bouillon cubes are widely consumed by poor households in sub-Saharan Africa. Because their main ingredient is salt, bouillon cubes could be a good source of iodine if iodized salt is used in their production and if their consumption by target groups is high. Our objective was to measure the iodine content of bouillon cubes, estimate their daily intake in school-aged children and evaluate their potential contribution to iodine intakes. Read More

    The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats.
    Iran J Basic Med Sci 2016 Oct;19(10):1040-1048
    Hacettepe University, Faculty of Pharmacy, Department of Toxicology, Ankara 06100 Turkey.
    Objectives: Particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. Fenvalerate is a pyrethroid insectide used in agriculture and has applications against a wide range of pests. This study was designed to evaluate the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzyme activities in the presence of iodine and/or selenium deficiency on a rat model. Read More

    Genotype-phenotype correlations of dyshormonogenetic goiter in children and adolescents from South India.
    Indian J Endocrinol Metab 2016 Nov-Dec;20(6):816-824
    Department of Biochemistry, MediCiti Institute of Medical Sciences, Hyderabad, Telangana, India.
    Background: Dyshormonogenetic goiter is one of the most common causes of hypothyroidism in children and adolescents in iodine nonendemic areas. The exact genotype-phenotypic correlations (GPCs) and risk categorization of hypothyroid phenotypes of dyshormonogenetic mutations are largely speculative. The genetic studies in pediatric dyshormonogenesis are very sparse from Indian sub-continent. Read More

    Iodine knowledge is positively associated with dietary iodine intake among women of childbearing age in the UK and Ireland.
    Br J Nutr 2016 Nov 18:1-8. Epub 2016 Nov 18.
    School of Biomedical Sciences,Northern Ireland Centre for Food and Health (NICHE),Ulster University,Cromore Road,Coleraine,County Londonderry,BT52 1SA,UK.
    Adequate I intake is important before conception and during pregnancy for optimal infant neurodevelopment. Recent studies have highlighted the prevalence of I deficiency in the UK and Ireland. It is possible that optimal I intake may be impeded by a poor knowledge of I nutrition. Read More

    Iodine biofortification of crops: agronomic biofortification, metabolic engineering and iodine bioavailability.
    Curr Opin Biotechnol 2016 Oct 27;44:16-26. Epub 2016 Oct 27.
    PlantLab, Institute of Life Sciences, Scuola Superiore Sant'Anna, 56124 Pisa, Italy. Electronic address:
    Iodine deficiency is a widespread micronutrient malnutrition problem, and the addition of iodine to table salt represents the most common prophylaxis tool. The biofortification of crops with iodine is a recent strategy to further enrich the human diet with a potentially cost-effective, well accepted and bioavailable iodine source. Understanding how iodine functions in higher plants is key to establishing suitable biofortification approaches. Read More

    Dietary Iodine Intake of the Australian Population after Introduction of a Mandatory Iodine Fortification Programme.
    Nutrients 2016 Nov 4;8(11). Epub 2016 Nov 4.
    School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong 2522, NSW, Australia.
    To address mild iodine deficiency in Australia, a mandatory fortification program of iodised salt in bread was implemented in 2009. This study aimed to determine factors associated with achieving an adequate dietary iodine intake in the Australian population post-fortification, and to assess whether bread consumption patterns affect iodine intake in high-risk groups. Using nationally representative data of repeated 24-h dietary recalls from the 2011-2012 Australian National Nutrition and Physical Activity Survey, dietary iodine intakes and food group contributions were compared by age, socioeconomic status (SES), and geographical remoteness (N = 7735). Read More

    Estimation of iodine nutrition and thyroid function status in late-gestation pregnant women in the United States: Development and application of a population-based pregnancy model.
    Toxicol Appl Pharmacol 2017 Jan 3;314:24-38. Epub 2016 Nov 3.
    Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address:
    Previously, a deterministic biologically-based dose-response (BBDR) pregnancy model was developed to evaluate moderate thyroid axis disturbances with and without thyroid-active chemical exposure in a near-term pregnant woman and fetus. In the current study, the existing BBDR model was adapted to include a wider functional range of iodine nutrition, including more severe iodine deficiency conditions, and to incorporate empirically the effects of homeostatic mechanisms. The extended model was further developed into a population-based model and was constructed using a Monte Carlo-based probabilistic framework. Read More

    Iodine Status over Two Decades: Influence of Seaweed Exposure.
    Ir Med J 2016 Jun 10;109(6):421. Epub 2016 Jun 10.
    School of Physics, NUI, Galway.
    Iodine deficiency is known to result in deficits in neuropsychological development in children born to iodine deficient mothers. However, a remedy in terms of iodisation of table salt as is the norm in most countries, has not been embraced by Ireland. The borderline iodine status of the Irish population persists unchanged over the past 20 years with the annual median urinary iodine (UI) varying from 62. Read More

    Can an Educational Intervention Improve Iodine Nutrition Status in Pregnant Women? A Randomized Controlled Trial.
    Thyroid 2017 Jan 30. Epub 2017 Jan 30.
    5 Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences , Tehran, Iran .
    Background: Because of their increased need for iodine, pregnant women are among the high-risk groups for iodine deficiency. The purpose of this study was to evaluate the effectiveness of an educational program on the iodine nutrition status of pregnant women.

    Methods: In this randomized controlled trial, 100 pregnant women were randomly selected from five healthcare centers in the southern region of Tehran, the capital of Iran. Read More

    Iodine deficiency in pregnancy is prevalent in vulnerable groups in Denmark.
    Dan Med J 2016 Nov;63(11)
    Introduction: Iodine is essential for the production of thyroid hormones. In pregnancy, physiological changes occur that can lead to iodine deficiency and impairment of fetal neurological development. We aimed to assess the iodine intake in pregnant women in Eastern Denmark, compare iodine levels in Eastern and Western Denmark and to identify potentially vulnerable groups. Read More

    Iodine deficiency and associated factors among school children: a cross-sectional study in Ethiopia.
    Arch Public Health 2016 31;74:46. Epub 2016 Oct 31.
    Department of Human Nutrition, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
    Background: Iodine deficiency remains a public health problem in the world. It is the leading cause of preventable mental retardation and brain damage worldwide. Though 12 million school age children are at risk of developing iodine deficiency, there is a scarcity of literature showing the magnitude of iodine deficiency in Ethiopia. Read More

    Neonatal thyrotropin concentration and iodine nutrition status of mothers: a systematic review and meta-analysis.
    Am J Clin Nutr 2016 Dec 2;104(6):1628-1638. Epub 2016 Nov 2.
    Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran; and
    Background: Low maternal iodine intake disturbs the thyroid function of neonates transiently or permanently.

    Objective: To our knowledge, we conducted one of the first systematic reviews and meta-analyses aimed at exploring the association of neonatal thyrotropin concentrations and iodine status of mothers during pregnancy and early postpartum periods.

    Design: Data were collected through literature searches for studies published between 1969 and 2015 with the use of electronic databases. Read More

    1 OF 110