35,880 results match your criteria Inverted Papilloma of the Urinary Bladder
Behav Brain Res 2018 Dec 3. Epub 2018 Dec 3.
Department of Psychiatry and Behavioral Sciences, Northwestern Feinberg School of Medicine, Chicago, IL, 60611, USA.
Diminished dopamine D1 stimulation may contribute to cognitive impairment in Alzheimer's and Parkinson's diseases, schizophrenia, and other neuropsychiatric disorders. However, orthosteric D1 receptor (D1R) agonists produce receptor desensitization and an inverted U-shaped dose-response curve, but positive allosteric modulators (PAMs) do not. We examined the cognitive effects of DETQ, a D1R PAM, in mice genetically modified to express the human D1 receptor ("hD1 mice"). Read More
J Phys Chem B 2018 Dec 6. Epub 2018 Dec 6.
Periodic, nanostructured porous polymer membranes made from the cross-linked inverted hexagonal phase of self-assembled lyotropic liquid crystals (LLCs) are a promising class of materials for selective separations. In this work, we investigate an experimentally characterized LLC polymer membrane using atomistic molecular modeling. In particular, we compare simulated X-ray diffraction (XRD) patterns with experimental XRD data to quantify and understand the differences between simulation and experiment. Read More
J Cheminform 2018 Dec 5;10(1):58. Epub 2018 Dec 5.
LASIGE, Faculdade de Ciências, Universidade de Lisboa, 1749 016, Lisbon, Portugal.
Named-entity recognition aims at identifying the fragments of text that mention entities of interest, that afterwards could be linked to a knowledge base where those entities are described. This manuscript presents our minimal named-entity recognition and linking tool (MER), designed with flexibility, autonomy and efficiency in mind. To annotate a given text, MER only requires: (1) a lexicon (text file) with the list of terms representing the entities of interest; (2) optionally a tab-separated values file with a link for each term; (3) and a Unix shell. Read More
Virus Genes 2018 Dec 5. Epub 2018 Dec 5.
Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Science, 666 Liuying Xi Road, Changchun, 130122, China.
Feline panleukopenia virus (FPV) infects cats and can be fatal to kittens. There is evidence that canine parvovirus originated from FPV, which makes FPV important in studies of the family Parvoviridae. In the present study, the entire genome of FPV strain HH-1/86 was converted into a full-length infectious clone (pFPV). Read More
Chem Phys Lipids 2018 Nov 30. Epub 2018 Nov 30.
Environmental Chemistry and Technology Graduate Program, College of Chemistry and Food Science, Federal University of Rio Grande, Av. Itália km 8, CarreirosCampus, Rio Grande, RS, 96201-900, Brazil. Electronic address:
The bioflavonoid quercetin may prevent magnetoliposomes oxidation, preserving their stability. In this work, the interaction between quercetin and asolectin-based magnetoliposomes was investigated by monitoring the hydration degree, vibrational, rotational and translational mobility parameters of the system as well as its thermodynamic properties. The efficiency of the encapsulation of maghemite magnetic nanoparticles was detected by high resolution-continuum source flame atomic absorption spectrometry (HR-CS FAAS). Read More
Anal Chem 2018 Dec 3. Epub 2018 Dec 3.
Ion motion in Trapped Ion Mobility Spectrometers (TIMS) and Inverted Drift Tubes (IDT) has been investigated. The 2D axi-symmetric analytical solution to the Nernst-Planck equation for constant gas flows and opposed linearly increasing fields is presented for the first time and is used to study the dynamics of ion distributions in the ramp region. It is shown that axial diffusion confinement is possible and that broad packets of ions injected initially into the system can be contracted. Read More
Langmuir 2018 Dec 3. Epub 2018 Dec 3.
Inverted conducting polymer/metal oxide core/shell structured pPPy/SiO2-TiO2 nanoparticles were prepared as electrorheological (ER) materials using sequential experimental methods. The core was synthesized via low-temperature self-assembly of PPy and SiO2 materials, and the outer TiO2 shell was easily coated onto the core part using a sol-gel method and a titanium isopropoxide precursor. Sonication-mediated etching and re-deposition was employed to etch out SiO2 portions from the core part to blend with TiO2 shells. Read More
J Investig Clin Dent 2018 Dec 2:e12377. Epub 2018 Dec 2.
Department of Maxillofacial Surgery, Faculty of Dentistry, Gaziosmanpasa University, Tokat, Turkey.
Aim: A mesiodens is the most frequent type of supernumerary tooth. They can be related to several complications, such as ectopic eruption and midline diastema. The aim of the present study was to assess the radiographic properties of mesiodens by analyzing the associated age, sex distribution, number of mesiodens per patient, shape, direction of eruption, and their association with complications. Read More
ACS Appl Energy Mater 2018 Nov 8;1(11):5977-5985. Epub 2018 Oct 8.
VTT Technical Research Centre of Finland, Kaitoväylä 1, P.O. Box 1100, FI-90571 Oulu, Finland.
Understanding the phenomena at interfaces is crucial for producing efficient and stable flexible organic solar cell modules. Minimized energy barriers enable efficient charge transfer, and good adhesion allows mechanical and environmental stability and thus increased lifetime. We utilize here the inverted organic solar module stack and standard photoactive materials (a blend of poly(3-hexylthiophene) and [6,6]-phenyl C61 butyric acid methyl ester) to study the interfaces in a pilot scale large-area roll-to-roll (R2R) process. Read More
Acta Pharm Sin B 2018 Oct 1;8(6):969-980. Epub 2018 Jun 1.
College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Owing to its great medicinal and ornamental values, is frequently adulterated with other species on the market. Unfortunately, the utilization of the common DNA markers ITS, ITS2, and + is unable to distinguish from 5 closely related species of it (, , , and ). Here, we compared 63 plastomes comprising 40 newly sequenced plastomes of the 6 species and 23 previously published plastomes. Read More
Indian J Plast Surg 2018 May-Aug;51(2):155-166
Department of Plastic Reconstructive and Faciomaxillary Surgery, Madras Medical College, Chennai, Tamil Nadu, India.
Introduction: The feeling of incongruence between phenotypic sex and psychological recognition of self-gender is termed gender dysphoria. Transsexualism is the most extreme form of this disorder.
Aims And Objectives: The aims and objectives of the study are to evaluate the esthetic and functional outcome of embryonic equivalents-based male-to-female sex reassignment surgery in transwomen using the institutional scoring system. Read More
Acta Psychol (Amst) 2018 Nov 29;192:146-152. Epub 2018 Nov 29.
Ghent University, Belgium.
Stimulus complexity is an important determinant of aesthetic preference. An influential idea is that increases in stimulus complexity lead to increased preference up to an optimal point after which preference decreases (inverted-U pattern). However, whereas some studies indeed observed this pattern, most studies instead showed an increased preference for more complexity. Read More
Gynecol Obstet Fertil Senol 2018 Nov 29. Epub 2018 Nov 29.
Département de gynécologie et obstétrique, hôpital Tenon, hôpitaux de Paris, Sorbonne université, AP-HP, 4, rue de la Chine, 75020 Paris, France.
Ecotoxicol Environ Saf 2018 Nov 28;169:714-721. Epub 2018 Nov 28.
Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, PR China; Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS); Shandong Provincial Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai 264003, PR China. Electronic address:
Cadmium is a known metal contaminant in the Bohai Sea. In this study, the dose-dependent responses induced by Cd were characterized in marine polychaete Perinereis aibuhitensis using the endpoints, including activities of enzymes, expression levels of stress-responsive genes and metabolic responses. Both enzyme activities and gene expression levels exhibited the hormetic effects induced by Cd in P. Read More
Int J Oral Maxillofac Surg 2018 Nov 27. Epub 2018 Nov 27.
Facial Cleft Deformity Clinic, Department of Maxillofacial and Oral Surgery, University of Pretoria, Pretoria, South Africa; Life Wilgers Hospital, Pretoria, South Africa.
The philtrum is an important aesthetic structure in the midface. A number of philtrum reconstruction techniques have been advocated for secondary cleft lip revision procedures. Conventional surgical management involves end-to-end orbicularis oris muscle approximation during primary cleft lip repair, often resulting in a flat lip appearance that requires secondary revision surgery at a later stage. Read More
Brain Connect 2018 Dec 1. Epub 2018 Dec 1.
Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States.
The insula has been implicated in playing important roles in various brain functions including consciousness, homeostasis, perception, self-awareness, language processing, and interpersonal experience. Abnormalities of the insula have been observed in patients suffering from addiction, deteriorating language function, anorexia, and emotional dysregulation. We analyzed typical development of insular connections in a large-scale pediatric population using 642 magnetic resonance imaging (MRI) examinations. Read More
Inorg Chem 2018 Dec 5. Epub 2018 Dec 5.
Centre for Nanoscience and Nanotechnology , SOA Deemed to be University , Bhubaneswar - 751030 Odisha , India.
Erection of a resourceful p-n heterojunction is a state-of-the-art tactic to flourish the charge anti-recombination process at the heterojunction interface and boost the photocatalytic activities under visible light irradiation. In the present work, we have engineered a new series of PbTiO/LaCrO (PT/LC) p-n heterojunction through a facile two-step combustion process. The structural, interface, and optical analysis distinctly revealed a strong intact between p-type LaCrO and n-type PbTiO, elucidating their electronic channelization and substantial reduction of electron-hole recombination at the PbTiO/LaCrO interface, which extend the lifetime and population of photogenerated charges in the p-n heterojunction material. Read More
Laryngoscope 2018 Dec 4. Epub 2018 Dec 4.
Department of Otolaryngology-Head and Neck Surgery, Stanford, California.
Objectives/hypothesis: Inverted papillomas (IPs) are benign tumors of the sinonasal tract with a malignant transformation potential. Predicting the transformation propensity of IPs and corresponding risk factors has long been a challenge. In this study, we aimed to use radiographic findings on magnetic resonance imaging (MRI) and computed tomography (CT) to help differentiate IP from IP-transformed squamous cell carcinomas (IP-SCC). Read More
Oral Maxillofac Surg 2018 Dec 4. Epub 2018 Dec 4.
Department of Oral and Maxillofacial Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-kogushi, Ube, Yamaguchi, 755-8505, Japan.
Background: Russell-Silver syndrome (RSS) is characterized by intrauterine growth retardation, short stature without postnatal catch-up growth, and an inverted triangular face with relative macrocephaly. There have been few case reports of RSS with cleft palate, in which perioperative problems such as difficult intubation due to trismus and impossibility to wear a mouth gag due to growth failure of the mandible were described. The case of a female RSS patient with cleft palate who underwent palatoplasty is reported. Read More
J Surg Case Rep 2018 Nov 30;2018(11):rjy321. Epub 2018 Nov 30.
Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK.
Sinonasal inverted papilloma (IP) is a benign tumour with an extremely low incidence in children. We report the case of an 11-year-old Caucasian male presenting with recurrent right-sided epistaxis, nasal obstruction and a mass in the right nasal cavity. An initial diagnosis of a nasopharyngeal angiofibroma was considered; however, on detailed histological examination, the mass was found to be an inverted papilloma. Read More
Front Pharmacol 2018 20;9:1105. Epub 2018 Nov 20.
School of Pharmacy, Anhui University of Chinese Medicine, Hefei, China.
Paeonol, an active compound isolated from the radix of , has been shown to have anti-atherosclerosis effects by regulating blood cells' function and protecting vascular cells injury. Besides, emerging evidences has proven that exosomes might play a pivotal role in intercellular communication by transmiting proteins and microRNAs from cell to cell. However, the relationship between monocytes-derived exosomal microRNA-223 and vascular inflammation injury along with paeonol' effects are still not clear. Read More
Sci Rep 2018 Dec 4;8(1):17626. Epub 2018 Dec 4.
Departments of Bioengineering, Material Science and Engineering, University of California, Berkeley, California, USA.
While cardiomyocytes differentiated from human induced pluripotent stems cells (hiPSCs) hold great promise for drug screening, the electrophysiological properties of these cells can be variable and immature, producing results that are significantly different from their human adult counterparts. Here, we describe a computational framework to address this limitation, and show how in silico methods, applied to measurements on immature cardiomyocytes, can be used to both identify drug action and to predict its effect in mature cells. Our synthetic and experimental results indicate that optically obtained waveforms of voltage and calcium from microphysiological systems can be inverted into information on drug ion channel blockage, and then, through assuming functional invariance of proteins during maturation, this data can be used to predict drug induced changes in mature ventricular cells. Read More
J Phys Chem B 2018 Dec 4. Epub 2018 Dec 4.
We present a thermodynamic analysis of the activation barrier for reactions which can be monitored through the difference in the energies of reactants and products defined as the reaction coordinate (electron and atom transfer, enzyme catalysis, etc). The free-energy surfaces along the reaction coordinate are separated into the enthalpy and entropy surfaces. For the Gaussian statistics of the reaction coordinate, the free-energy surfaces are parabolas, and the entropy surface is an inverted parabola. Read More
ACS Nano 2018 Dec 4. Epub 2018 Dec 4.
Solid-state nanopores are single-molecule sensors that hold great potential for rapid protein and nucleic-acid analysis. Despite their many opportunities, the conventional ionic current detection scheme that is at the heart of the sensor suffers inherent limitations. This scheme intrinsically couples signal strength to the driving voltage, requires the use of high-concentration electrolytes, suffers from capacitive noise, and impairs high-density sensor integration. Read More
Nat Commun 2018 Dec 3;9(1):5205. Epub 2018 Dec 3.
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA.
The originally published version of this Article contained errors in Figure 5, for which we apologise. In panel c, the scatter graph was inadvertently replaced with a scatter graph comprising a subset of data points from panel d. Furthermore, the legends to Figures 5c and 5d were inverted. Read More
BMC Plant Biol 2018 Dec 3;18(1):321. Epub 2018 Dec 3.
Department of Botany and Nature Protection, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Background: Comparative analyses of chloroplast and mitochondrial genomes have shown that organelle genomes in bryophytes evolve slowly. However, in contrast to seed plants, the organellar genomes are yet poorly explored in bryophytes, especially among liverworts. Discovering another organellar genomes of liverwort species by sequencing provides new conclusions on evolution of bryophytes. Read More
Biomacromolecules 2018 Nov 30. Epub 2018 Nov 30.
We report a novel method to prepare capsules, beads or open-cell materials from Pickering emulsions of monomers, stabilized by cellulose nanocrystals (CNCs) grafted with reactive Isobutyrate bromide moieties (CNC-Br). CNC-Br particles with different hydrophylic/hydrophobic balance at their surface were prepared, and subsequently used to stabilize direct (O/W), inverted (W/O), or double emulsions of Styrene or n-BuA. The different emulsions obtained were subsequently polymerized, by initiating an AGET-ATRP polymerization from the brominated particles surrounding the stabilized droplets. Read More
J Org Chem 2018 Nov 30. Epub 2018 Nov 30.
Two examples of highly unsymmetrical heterobenzisapphyrins containing one benzene, two pyrroles, one furan and one thiophene rings connected via four meso carbons and one direct bond were prepared over a sequence of five steps in 8-9% yields. The X-ray structure revealed that the furan ring was inverted from the macrocyclic framework and the macrocycle was nearly planar. Spectral and electrochemical studies indicated that the macrocycle was nonaromatic in nature due to lack of conjugation. Read More
J Phys Chem Lett 2018 Nov 30. Epub 2018 Nov 30.
The instability issue of Pb-free Sn-based perovskite is one of the biggest challenges towards its application in optoelectronic device. Herein, a structural regulation strategy is demonstrated to regulate the geometric symmetry of formamidiniumtin iodide (FASnI3) perovskite. Experimental and theoretical works show that the introduction of cesium cation (Cs+) could improve the geometric symmetry, suppress the oxidation of Sn2+, and enhance the thermodynamical structural stability of FASnI3. Read More
Curr Genet 2018 Nov 29. Epub 2018 Nov 29.
Department of Biology, Faculty of Education and Integrated Arts and Sciences, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo, 162-8480, Japan.
DNA sequences that read the same from 5' to 3' in either strand are called inverted repeat sequences or simply IRs. They are found throughout a wide variety of genomes, from prokaryotes to eukaryotes. Despite extensive research, their in vivo functions, if any, remain unclear. Read More
ISA Trans 2018 Oct 25. Epub 2018 Oct 25.
Department of Electrical Engineering, National Central University, Jhong-Li 32001, Taiwan, ROC. Electronic address:
A robust fuzzy controller (RFC) is proposed for a ball inverted pendulum (BIP) system control problem. A Mamdani-type fuzzy controller and a compensated control technique are combined in the proposed control system. This controller is used for real-world control of a BIP with unknown system uncertainties. Read More
Med Phys J 1801 May;5(27):450-452
Cell Physiol Biochem 2018 Nov 29;51(4):1616-1631. Epub 2018 Nov 29.
Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, China.
Background/aims: The emergence of multidrug resistance (MDR) caused by P-glycoprotein (P-gp) overexpression is a serious obstacle to the treatment of chronic myelocytic leukemia. In recent years, some clinical trials have shown that nelfinavir (NFV), a traditional anti-HIV drug, has anti-cancer effects. Some researchers have also shown NFV might be a potential P-gp inhibitor. Read More
PLoS Biol 2018 Nov 29;16(11):e2006577. Epub 2018 Nov 29.
Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
The interferon (IFN)-mediated innate immune response is the first line of defense against viruses. However, an IFN-stimulated gene, the adenosine deaminase acting on RNA 1 (ADAR1), favors the replication of several viruses. ADAR1 binds double-stranded RNA and converts adenosine to inosine by deamination. Read More
Biochim Biophys Acta Gene Regul Mech 2018 Oct 26;1861(10):928-937. Epub 2018 Aug 26.
State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266237, China. Electronic address:
Chaperonin groEL genes are duplicated in approximately 20% of bacteria, and the duplicates are differentially transcribed due to their divergent functions. The coordinated regulation of this differential transcription is as yet undetermined. In this study, we reported that the controlling inverted repeat of chaperone expression (CIRCE) element (the HrcA-binding site located upstream of the promoter) evolved for the transcriptional regulation of duplicate groELs. Read More
Minerva Gastroenterol Dietol 2018 Nov 27. Epub 2018 Nov 27.
National Health Laboratory Service, Department of Chemical Pathology, University of the Witwatersrand Medical School, Johannesburg, South Africa.
Background: The aim of the study was to determine the prevalence of gastroesophageal reflux disease (GORD) in a black population in South Africa and to determine if there was any association with obesity.
Methods: A sample of 312 black subjects was randomly selected and interviewed with a structured questionnaire (GerdQ) consisting of six questions translated into English and two of the most commonly used African languages (Zulu and Xhosa). This question-based symptom score for the diagnosis of GORD has been validated previously. Read More
Environ Sci Pollut Res Int 2018 Nov 28. Epub 2018 Nov 28.
Department of Management, College of Business Administration, King Saud University, Riyadh, Saudi Arabia.
The relationship between renewable energy consumption (REC), foreign direct investment (FDI) inflows, economic growth, and their resulting impact on CO2 emissions is widely discussed area in energy and environmental literature; however, there is an unseen literature on moderation and mediation effect of per capita income and FDI inflows with the renewable energy consumption on CO2 emissions in developing countries like Pakistan, which is being evaluated in this study by using a consistent time series data for a period of 1975-2016. The results show that economic growth and FDI inflows both increase CO2 emissions, while REC substantially decreases CO2 emissions during the study time period. The results do not support the inverted U-shaped Environmental Kuznets Curve (EKC) hypothesis for per capita income (and FDI inflows) and per capita CO2 emissions in a country. Read More
Int J Mol Sci 2018 Nov 28;19(12). Epub 2018 Nov 28.
Key Laboratory of Aquatic Botany and Watershed Ecology, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan 430074, China.
The order Nymphaeales, consisting of three families with a record of eight genera, has gained significant interest from botanists, probably due to its position as a basal angiosperm. The phylogenetic relationships within the order have been well studied; however, a few controversial nodes still remain in the Nymphaeaceae. The position of the genus and the monophyly of the Nymphaeaceae family remain uncertain. Read More
Micromachines (Basel) 2018 Nov 27;9(12). Epub 2018 Nov 27.
Key Laboratory of Agricultural Information Acquisition Technology, Ministry of Agriculture, China Agricultural University, Beijing 100083, China.
Immunomagnetic separation has been widely used for the separation and concentration of foodborne pathogens from complex food samples, however it can only handle a small volume of samples. In this paper, we presented a novel fluidic device for the specific and efficient separation and concentration of using self-assembled magnetic nanoparticle chains. The laminated sawtooth-shaped iron foils were first mounted in the 3D-printed matrix and magnetized by a strong magnet to generate dot-array high gradient magnetic fields in the fluidic channel, which was simulated using COMSOL (5. Read More
PLoS One 2018 28;13(11):e0207249. Epub 2018 Nov 28.
Monterey Bay Aquarium Research Institute, Moss Landing, California, United States of America.
Pelagic crustaceans are arguably the most abundant group of metazoans on Earth, yet little is known about their natural behavior. The deep pelagic shrimp Hymenopenaeus doris is a common decapod that thrives in low oxygen layers of the eastern Pacific Ocean. When first observed in situ using a remotely operated vehicle, most specimens of H. Read More
Org Lett 2018 Nov 28. Epub 2018 Nov 28.
Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Jiangsu National Synergetic Innovation Center for Advanced Materials , Nanjing Tech University , 30 South Puzhu Road , Nanjing , 211816 , P. R. China.
Under photoredox catalysis conditions, the conventional electrophilic reactivity of ketimines is inverted to generate nucleophilic species. As a result, chemoselective cross-electrophile couplings between aldehydes and ketimines are achieved via umpolung reactivity of ketimines to furnish amino alcohols (44 examples with good to excellent yields). To illustrate the utility of the amino alcohol products, 1,2-dihydroindol-3-one-based fluorophores are easily synthesized using the coupling products. Read More
Chromosoma 2018 Nov 27. Epub 2018 Nov 27.
Department of Botany and Plant Sciences, University of California, Riverside, CA, 92521, USA.
Chromosome pairing in meiosis usually starts in the vicinity of the telomere attachment to the nuclear membrane and congregation of telomeres in the leptotene bouquet is believed responsible for bringing homologue pairs together. In a heterozygote for an inversion of a rye (Secale cereale L.) chromosome arm in wheat, a distal segment of the normal homologue is capable of chiasmate pairing with its counterpart in the inverted arm, located near the centromere. Read More
ISA Trans 2018 Oct 17. Epub 2018 Oct 17.
School of Mechanical Engineering, Shiraz University, shiraz, Iran.
In this paper, a novel interval type-2 fuzzy fractional order super twisting algorithm (IT2FFOSTA) which is essentially a second order sliding mode controller is presented. The proposed IT2FFOSTA enhances fractional order super twisting algorithm (FOSTA) by taking advantage of an interval type-2 fuzzy fractional order sliding surface (IT2FFOSS) for some classes of fully-actuated and under-actuated nonlinear systems in presence of uncertainty. The FOSTA significantly reduces the amount of chattering and the IT2FFOSS results in decreasing the tracking error, control effort, and chattering level. Read More
Hear Res 2018 Oct 19. Epub 2018 Oct 19.
University of Antwerp, Biophysics and Biomedical Physics, Groenenborgerlaan 171, 2020, Antwerp, Belgium.
In the single-ossicle ear of chickens, the quasi-static displacement of the umbo shows great asymmetry; umbo displacements are much larger for negative than for positive pressure in the middle ear, which is opposite to the typical asymmetry observed in mammal ears. To better understand this behavior, a finite-element model was created of the static response of the chicken middle ear. The role of flexibility of the extracolumella in the model was investigated, and the potential effect of the outward orientation of the tympanic-membrane cone was studied by building two adapted models with a flat membrane and an inverted conical membrane. Read More
Life Sci Space Res (Amst) 2018 Nov 31;19:1-12. Epub 2018 Jul 31.
The Portuguese Sea and Atmosphere Institute, I.P. (IPMA, IP), Sea and Marine Resources Department (DMRM), R. Alfredo Magalhães Ramalho, 6, Lisbon 1495-006, Portugal. Electronic address:
The chain-forming dinoflagellate Alexandrium catenella was grown with LED or fluorescent light. With LED light, the pool of mycosporine-like amino acids (MAAs) with strong antioxidant properties, such as mycosporine-glycine and palythene, was reduced in comparison to fluorescent light. The conjugated MAAs M-320 and M-335/360 presented similar stability to light and oxidation than their respective more sensitive moiety: mycosporine-glycine and palythene, respectively. Read More
Cell Physiol Biochem 2018 Nov 27;51(3):1164-1178. Epub 2018 Nov 27.
Department of Physiology, (Cellular Physiology and Muscle Physiology Research Groups), Institute of Molecular Pathology Biomarkers, University of Extremadura, Cáceres, Spain.
Background/aims: STIM1 and Orai1 are the key components of store-operated Ca2+ entry (SOCE). Among the proteins involved in the regulation of SOCE, SARAF prevents spontaneous activation of SOCE and modulates STIM1 function.
Methods: Cytosolic Ca2+ mobilization was estimated in fura-2-loaded cells using an epifluorescence inverted microscope. Read More
Syst Biol 2018 Nov 27. Epub 2018 Nov 27.
School of Earth, Environmental and Biological Sciences, Queensland University of Technology, Brisbane, QLD, Australia.
Combined "total evidence" analysis of molecular and morphological data offers the opportunity to objectively merge fossils into the tree of life, and challenges the primacy of solely DNA based phylogenetic and dating inference, even among modern taxa. To investigate the relative utility of DNA, morphology, and total evidence for evolutionary inference, we sequenced the first near-complete mitochondrial genomes from extinct Australian megafauna: a 40-50 thousand year old giant short-faced kangaroo (Simosthenurus occidentalis) and giant wallaby (Protemnodon anak). We analysed the ancient DNA and fossil data alongside comparable data from extant species to infer phylogeny, divergence times, and ancestral body mass among macropods (kangaroos and wallabies). Read More
Small 2018 Nov 27:e1804692. Epub 2018 Nov 27.
State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, 2699 Qianjin Street, Changchun, 130012, P. R. China.
To overcome the zigzag pathway transport of the electron diffusion process and eliminate the surface trap states of phenyl-C61-butyric acid methyl ester (PCBM) nanofilms in inverted perovskite solar cells, novel 1D N-type doped carbon nanorods (CNRs) are developed by a stibonium (Sb) auxiliary ball milling method and introduced into the PCBM film to prepare the PCBM:Sb-CNRs hybrid transport layer. In this way, the N-type doped Sb-CNRs can extend the built-in electric field between CH NH PbI and PCBM to facilitate the separation of electron/hole pairs. The discontinuous band with the built-in potential in the PCBM/Sb-CNRs heterojunction can boost interfacial charge redistribution and promote electrons diffusion from PCBM to electrode through 1D Sb-CNRs network. Read More
PeerJ 2018 13;6:e5855. Epub 2018 Nov 13.
School of Electrical Engineering and Computer Science, National University of Sciences and Technology, Islamabad, Pakistan.
Segmentation of the retinal blood vessels using filtering techniques is a widely used step in the development of an automated system for diagnostic retinal image analysis. This paper optimized the blood vessel segmentation, by extending the trainable B-COSFIRE filter via identification of more optimal parameters. The filter parameters are introduced using an optimization procedure to three public datasets (STARE, DRIVE, and CHASE-DB1). Read More
Genes (Basel) 2018 Nov 23;9(12). Epub 2018 Nov 23.
Key Laboratory for Forest Genetic and Tree Improvement and Propagation in Universities of Yunnan Province, Southwest Forestry University, Kunming 650224, China.
Inverted cuttings of remain alive by rooting from the original morphological apex and sprouting from the base, but the lateral branches exhibit less vigorous growth than those of the upright plant. In this study, we examined the changes in hormone contents, oxidase activities, and transcriptome profiles between upright and inverted cuttings of . The results showed that the indole-3-acetic acid (IAA) and gibberellic acid (GA₃) contents were significantly lower in inverted cuttings than in upright cuttings only in the late growth period (September and October), while the abscisic acid (ABA) level was always similar between the two direction types. Read More