153,874 results match your criteria Intracranial Epidural Abscess


Middle Meningeal Artery to Premeatal Anterior Inferior Cerebellar Artery Bypass Via Anterior Petrosectomy: An Anatomic Feasibility Study.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurological Surgery, University of California, San Francisco, California, USA; Skull Base and Cerebrovascular Laboratory, University of California, San Francisco, California, USA. Electronic address: http://skullbaselab.ucsf.edu.

Introduction: Anterior-inferior cerebellar artery (AICA) aneurysms are rare with no optimal consensus on management strategies. When the treatment requires parent artery occlusion post-operative ischemic or neuropathic, complications can occur.

Objective: To evaluate the feasibility of direct revascularization of premeatal AICA using the middle meningeal artery (MMA) as the donor through an anterior petrosectomy (APA) window. Read More

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December 2018

Left Atrial Appendage Closure Device Implantation in Patients with Prior Intracranial Hemorrhage.

Heart Rhythm 2018 Nov 19. Epub 2018 Nov 19.

Section of Cardiac Pacing and Electrophysiology, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, OH. Electronic address:

Background: The Watchman™ device (Boston Scientific, MN), used for left atrial appendage closure (LAAC) was approved for stroke prevention in patients with atrial fibrillation (AF) and an appropriate rationale to avoid long-term oral anticoagulation. Patients with AF and prior intracranial hemorrhage (ICH) were excluded from clinical trials due to perceived risks of peri-operative anticoagulation.

Objective: We studied the efficacy and safety of LAAC using Watchman™ in patients with AF and prior ICH. Read More

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November 2018

Small cell bladder cancer: should we consider prophylactic cranial irradiation?

Int Braz J Urol 2018 Oct 30;44. Epub 2018 Oct 30.

Department of Urology, University of Pittsburgh, Pennsylvania, U.S.A.

Purpose: To describe the clinical characteristics, treatment patterns, and outcomes in patients with small cell bladder cancer at our institution, including those who received prophylactic cranial irradiation (PCI) for the prevention of intracranial recurrence.

Materials And Methods: Patients with small cell bladder cancer treated at a single institution between January 1990 and August 2015 were identified and analyzed retrospectively for demographics, tumor stage, treatment, and overall survival.

Results: Of 44 patients diagnosed with small cell bladder cancer, 11 (25%) had metastatic disease at the time of presentation. Read More

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October 2018
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Platelet transfusion practices in immune thrombocytopenia related hospitalizations.

Transfusion 2018 Dec 5. Epub 2018 Dec 5.

Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Division of Hematology/Oncology, Emory University School of Medicine, Atlanta, Georgia.

Background: The role of platelet transfusions in management of Immune Thrombocytopenia (ITP) remains controversial. Current guidelines recommend that platelet transfusions in ITP be reserved for catastrophic hemorrhage or invasive surgical procedures. This study assesses the nationwide platelet transfusion practices in hospitalized children and adults with ITP. Read More

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December 2018
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MRI Presentation of Infectious Intracranial Aneurysms in Infective Endocarditis.

Neurocrit Care 2018 Dec 5. Epub 2018 Dec 5.

Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.

Background: The radiographic appearance of infectious intracranial aneurysms (IIAs) of infective endocarditis (IE) on magnetic resonance imaging (MRI) of brain is varied. We aimed to describe the IIA-specific MRI features in a series of patients with IIAs.

Methods: Records of patients with active IE who had digital subtraction angiography (DSA) at a tertiary medical center from January 2011 to December 2016 were reviewed. Read More

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December 2018
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The application of fluorescence techniques in meningioma surgery-a review.

Neurosurg Rev 2018 Dec 6. Epub 2018 Dec 6.

Department of Neurosurgery, University Medical Center Groningen, University of Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.

Surgical resections of meningiomas, the most common intracranial tumor in adults, can only be curative if radical resection is achieved. Potentially, the extent of resection could be improved, especially in complex and/or high-grade meningiomas by fluorescence-guided surgery using 5-aminolevulinic acid (5-ALA), indocyanine green (ICG), or fluorescein. This review aims to summarize and evaluate these fluorescence-guided meningioma surgery techniques. Read More

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December 2018

Thromboembolic Complications Following Tissue Plasminogen Activator Therapy in Patients of Acute Ischemic Stroke - Case Report and Possibility for Detection of Cardiac Thrombi.

Open Med (Wars) 2018 19;13:551-555. Epub 2018 Nov 19.

Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, 30-1 Oyaguchi Kamimachi, Itabashi-ku, Tokyo Japan.

Many reports focus on the probability of intracranial hemorrhage as a complication after recombinant tissue plasminogen activator (rt-PA) therapy. However, thromboembolic complications are not well discussed. We experienced a case in which severe thromboembolic complications occurred in the right radial and right ulnar artery. Read More

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November 2018

Microembolic signal detection by transcranial Doppler: Old method with a new indication.

World J Methodol 2018 Nov 29;8(3):40-43. Epub 2018 Nov 29.

Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand.

Transcranial Doppler (TCD) is useful for investigation of intracranial arterial blood flow and can be used to detect a real-time embolic signal. Unfortunately, artefacts can mimic the embolic signal, complicating interpretation and necessitating expert-level opinion to distinguish the two. Resolving this situation is critical to achieve improved accuracy and utility of TCD for patients with disrupted intracranial arterial blood flow, such as stroke victims. Read More

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November 2018

Comprehensive Review of Spinal Neurenteric Cysts with a Focus on Histopathological Findings.

Cureus 2018 Sep 28;10(9):e3379. Epub 2018 Sep 28.

Neurosurgery, Seattle Science Foundation, Seattle, USA.

Among the occult spinal dysraphisms, neurenteric cysts (NECs) are rare and are thought to arise due to a failure of the separation of the primitive endoderm and ectoderm. Patients experience various neurological symptoms depending on the location of the lesion. As the epithelial morphology of NECs share similarities with other intracranial and intraspinal cystic growths, the definitive diagnosis of NEC can be made after a histochemical analysis with endodermal markers. Read More

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September 2018

Feasibility and Efficacy of Simultaneous Integrated Boost Intensity-modulated Radiation Therapy based on MRI-CT fusion in Patients with Brain Metastases of Non-small Cell Lung Cancer.

J Cancer 2018 31;9(23):4477-4483. Epub 2018 Oct 31.

Department of Radiation Oncology, Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, China.

To assess the feasibility and therapeutic effects of simultaneous integrated boost intensity-modulated radiation therapy (SIB-IMRT) based on the fusion imaging of magnetic resonance imaging (MRI) and computed tomography (CT) as a dose-intensive technique in patients with brain metastases (BM) of non-small cell lung cancer (NSCLC). Forty-six NSCLC patients with 1 to 7 brain metastases were enrolled in this retrospective study between November, 2011 and February, 2017. Thirty-one patients (67. Read More

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October 2018
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First clinical experiences of concurrent bleeding control and intracranial pressure monitoring using a hybrid emergency room system in patients with multiple injuries.

World J Emerg Surg 2018 29;13:56. Epub 2018 Nov 29.

Division of Trauma and Surgical Critical Care, Osaka General Medical Center, 3-1-56 Bandai-Higashi, Sumiyoshi-ku, Osaka, 558-8558 Japan.

Background: The outcomes of multiple injury patients with concomitant torso hemorrhage and traumatic brain injury (TBI) are very poor. The hybrid emergency room system (HERS) is a trauma management system designed to complete resuscitation, computed tomography (CT), surgery, angioembolization, and intracranial pressure (ICP) monitoring all in one trauma resuscitation room without patient transfer. We aimed to review the outcomes of polytrauma patients who underwent concurrent bleeding control and ICP monitoring using the HERS. Read More

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November 2018
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Cerebrovascular Function in the Large Arteries Is Maintained Following Moderate Intensity Exercise.

Front Physiol 2018 21;9:1657. Epub 2018 Nov 21.

Centre for Heart Lung and Vascular Health, School of Health and Exercise Science, University of British Columbia Okanagan, Kelowna, BC, Canada.

Exercise has been shown to induce cerebrovascular adaptations. However, the underlying temporal dynamics are poorly understood, and regional variation in the vascular response to exercise has been observed in the large cerebral arteries. Here, we sought to measure the cerebrovascular effects of a single 20-min session of moderate-intensity exercise in the one hour period immediately following exercise cessation. Read More

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November 2018

Transient Anarthria and Quadriplegia in a Patient with Basilar Artery Hypoplasia and Coincidental Intracranial Lipoma: A Case Report.

Case Rep Neurol 2018 Sep-Dec;10(3):322-327. Epub 2018 Nov 14.

Department of Neurology, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea.

Cerebral ischemia may be rarely associated with a hypoplastic vertebrobasilar system. Intracranial lipoma is also a very rare congenital malformation. We report the case of a 52-year-old woman with vertebrobasilar transient ischemic attack associated with basilar artery hypoplasia and coincidental intracranial lipoma. Read More

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November 2018
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The role of postoperative radiotherapy in pediatric patients with grade II intracranial ependymomas: a population-based, propensity score-matched study.

Cancer Manag Res 2018 8;10:5515-5524. Epub 2018 Nov 8.

Department of Neurosurgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China,

Purpose: The main objectives of this study were to clarify the efficacy of postoperative radiotherapy (PORT) for pediatric intracranial grade II ependymomas (EPNs) and to explore whether various characteristics are associated with different outcomes in patients with and without PORT.

Patients And Methods: Data from patients younger than 18 years diagnosed with grade II intracranial EPNs and treated by surgery, with or without PORT, were obtained from the Surveillance, Epidemiology, and End Results (SEER) database (1973-2013 data set). Propensity score-matched analysis was conducted to balance clinical variables. Read More

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November 2018
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Severity of enterovirus A71 infection in a human SCARB2 knock-in mouse model is dependent on infectious strain and route.

Emerg Microbes Infect 2018 Dec 5;7(1):205. Epub 2018 Dec 5.

Department of Medical Microbiology, Capital Medical University, Beijing, 100069, China.

Enterovirus A71 (EV-A71) is a major etiological agent of human hand, foot and mouth disease, and it can cause severe neurological complications. Although several genotypes of EV-A71 strains are prevalent in different regions of the world, the genotype C4 has circulated in mainland China for more than 20 years. The pathogenicity of different EV-A71 clinical isolates varies and needs to be explored. Read More

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December 2018
7 Reads

Three-dimensional volumetric magnetic resonance imaging (MRI) analysis of the soft palate and nasopharynx in brachycephalic and non-brachycephalic dog breeds.

J Vet Med Sci 2018 Dec 5. Epub 2018 Dec 5.

Section of Medical Imaging, Veterinary Medical Center, Chungbuk National University.

The purpose of this study was to use magnetic resonance imaging (MRI) to compare the volumes and three-dimensional configurations of the soft palate and nasopharynx in non-brachycephalic and brachycephalic dogs with different body weights, and infer which factors influence nasopharyngeal volume. This was a retrospective observational study. The brain MRI medical records of all dogs referred to the Veterinary Medical Center, Chungbuk National University, between 2013 and 2016, for evaluation of intracranial disease were reviewed. Read More

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December 2018
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Intracranial dural arteriovenous fistula mistaken as cervical transverse myelitis.

Pract Neurol 2018 Dec 5. Epub 2018 Dec 5.

Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK

We describe a man with an intracranial dural arteriovenous fistula that presented as a subacute longitudinally extensive cervical myelopathy. The uncommon location of the fistula and the absence of specific radiological signs resulted in initial misdiagnosis as longitudinally extensive transverse myelitis. Neurologists should have a high index of suspicion for dural arteriovenous fistula in older men, especially those with subacute or chronic symptoms, acellular cerebrospinal fluid and, particularly, if there is neurological deterioration soon after corticosteroid treatment. Read More

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December 2018

Trajectories of early secondary insults correlate to outcomes of traumatic brain injury: results from a large, single centre, observational study.

BMC Emerg Med 2018 Dec 5;18(1):52. Epub 2018 Dec 5.

School of Medicine and Surgery, University of Milan-Bicocca, Via Cadore 48, 20900, Monza, MB, Italy.

Background: Secondary insults (SI), such as hypotension, hypoxia, and intracranial hypertension frequently occur after traumatic brain injury (TBI), and have a strong impact on patients' clinical outcomes. The aim of this study is to examine the trajectories of SI from the early phase of injury in the prehospital setting to hospital admission in a cohort of TBI patients.

Methods: This is a retrospective, observational, single centre study on consecutive patients admitted from 1997 to 2016 to the Neuro Intensive Care Unit (NICU) at San Gerardo Hospital, in Monza, Italy. Read More

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December 2018

Diagnostic and prognostic value of the optic nerve sheath diameter with respect to the intracranial pressure and neurological outcome of patients following hemicraniectomy.

BMC Neurol 2018 Dec 5;18(1):199. Epub 2018 Dec 5.

Department of Emergency Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88, Jiefang Road, Hangzhou City, 310009, Zhejiang Province, China.

Background: In cases showing cerebrospinal fluid (CSF) redistribution as a compensatory mechanism in acute intracranial hypertension, the optic nerve sheath diameter (ONSD) can be used to estimate intracranial pressure (ICP). However, it remains unclear whether the ONSD can be applied in patients with skull defects after a craniectomy, because the primary injury or surgical craniectomy may alter the dynamics of the CSF circulation or structure of the optical nerve sheath. This study explored the value of the ONSD in patients after a hemicraniectomy. Read More

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December 2018

Preliminary Clinical Microneurosurgical Experience With the 4K3-Dimensional Microvideoscope (ORBEYE) System for Microneurological Surgery: Observation Study.

Oper Neurosurg (Hagerstown) 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan.

Background: The exoscope has been reported as a novel neurosurgical instrumentation in clinical practice.

Objective: To investigate the possibility that ORBEYE (OE), a novel instrument that excludes eyepiece lenses and allows for microsurgery by observation of the 4K3D monitor, could replace microscopes.

Methods: We report 22 clinical cases by 5 experienced neurosurgeons and the comparative results of training 10 residents. Read More

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December 2018

Association of Seizure Spread With Surgical Failure in Epilepsy.

JAMA Neurol 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut.

Importance: Seizures recur in as many as half of patients who undergo surgery for drug-resistant temporal lobe epilepsy (TLE). Understanding why TLE is resistant to surgery in some patients may reveal insights into epileptogenic networks and direct new therapies to improve outcomes.

Objective: To characterize features of surgically refractory TLE. Read More

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December 2018

Anterior Cranial Vault Reconstruction With Distraction for Primary and Secondary Craniosynostosis Repair.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Division of Plastic and Reconstructive Surgery, University of Nebraska Medical Center, Omaha, NE.

Traditional fronto-orbital advancement continues to be a useful operation for correction of craniosynostosis involving the coronal or metopic sutures. Recently, distraction osteogenesis has been used to correct a variety of cranial deformities. Studies have mostly focused on posterior vault distraction due to its simplicity and greater volume gain when compared with anterior vault distraction. Read More

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November 2018

Wider Suturectomy Before Posterior Distraction for Craniosynostosis.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Plastic Surgery, Osaka Medical College.

The aim of the surgery for craniosynostosis is to release increased intracranial pressure and to normalize cranial shape. The procedure has developed so far in Japan, from a simple strip craniectomy before 1960s through a total calvarial remodeling after 1970s and later methods of 1990s, such as distraction and its modifications applying to the posterior cranium. Since a distracter needs certain hardness and thickness of the bone, the surgery has to be stood by until 5 to 6 months of age. Read More

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November 2018

Cone Beam Computed Tomographic Evaluation of Intracranial Physiologic Calcifications.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Dentomaxillofacial Radiology Department, Faculty of Dentistry, Ankara University, Ankara, Turkey.

Objective: The aim of the present study was to evaluate the incidence of physiologic intracranial calcifications detected in cone beam computed tomography (CBCT) images of a Turkish subpopulation.

Methods: The CBCT image of the full head of 573 patients taken between 2015 and 2018 was evaluated retrospectively. The prevalence of habenular calcification, petroclinoid ligament, coroid plexus, interclinoid ligament (ICL), and carotico-clinoid ligament (CCL) calcifications was investigated. Read More

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November 2018

Study on the Therapeutic Effects of Trigeminal Neuralgia With Microvascular Decompression and Stereotactic Gamma Knife Surgery in the Elderly.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Neurosurgery, The Second Hospital of Shandong University, Jinan, China.

Objective: The aim of the study was to evaluate the efficacy of microvascular decompression (MVD) and stereotactic gamma knife surgery (GKS) in the treatment of trigeminal neuralgia (TN) in the elderly.

Patients And Methods: Retrospective analysis of 137 elderly cases with TN underwent MVD, partial sensory rhizotomy (PR) treatment from August 2007 to March 2017 and 56 cases underwent GKS treatment from May 2014 to February 2017 was made, compared the efficacy of MVD and GKS in different age groups.

Results: In 125 patients of MVD alone, the responsible vessels included 60 cases of superior cerebellar artery, 55 cases of anterior inferior cerebellar artery, 4 cases of venous vascular compression, 13 cases of mixed arteriovenous compression and 3 cases of vertebral artery, and 2 cases of no responsible vessel. Read More

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November 2018

Management of sphenoid lateral recess encephalocoeles.

Curr Opin Otolaryngol Head Neck Surg 2018 Nov 16. Epub 2018 Nov 16.

Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Purpose Of Review: Sphenoid sinus lateral recess encephalocoeles (SSLRE) are rare occurrences and pose unique challenges due to limited surgical access for endoscopic endonasal repair and also the lack of consensus on optimal perioperative managements specifically in the spontaneous cases, which are also believed to be a variant of idiopathic intracranial hypertension (IIH). Endoscopic endonasal approaches have largely replaced the transcranial route and the techniques are continuously being refined to reduce the neurovascular morbidity and improve outcome.

Recent Findings: Transpetrygoid is the most utilized approach with modifications suggested to limit bone removal, exposure and preservation of the neurovascular structures as dictated by the extent of the lateral recess. Read More

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November 2018

Systematic review with meta-analysis: the risk of gastrointestinal bleeding in patients taking third-generation P2Y inhibitors compared with clopidogrel.

Aliment Pharmacol Ther 2018 Dec 2. Epub 2018 Dec 2.

Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.

Background: Ticagrelor and prasugrel are third-generation oral P2Y receptor antagonists with rapid onset and pronounced platelet inhibition. However, higher overall bleeding rates have been reported for these agents when compared with clopidogrel.

Aim: To compare the risk of gastrointestinal bleeding (GIB) among users of third-generation P2Y inhibitors with clopidogrel. Read More

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December 2018

Anesthesia for endovascular treatment in anterior circulation stroke: A systematic review and meta-analysis.

Brain Behav 2018 Dec 3:e01178. Epub 2018 Dec 3.

Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Background: Endovascular treatment in patients with acute anterior circulation stroke could be performed under either conscious sedation (CS) or general anesthesia (GA). Although several studies have investigated the association between the clinical outcomes and the two anesthesia methods, consensus is lacking.

Methods: PubMed and EMBASE searches were used to select full-text articles comparing the effects of GA and CS on functional outcome and complications in patients with anterior circulation ischemic stroke. Read More

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December 2018

Nasal septal abscess: a 10-year retrospective study.

Eur Arch Otorhinolaryngol 2018 Nov 30. Epub 2018 Nov 30.

Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Cheng-Kung Road Section 2, Taipei 114, Taiwan, ROC.

Objective: Nasal septal abscess is an uncommon condition but it can cause potentially life-threatening intracranial complications and cosmetic nasal deformity.

Methods: We analyzed ten years of cases to determine the optimal diagnostic and therapeutic modalities. A retrospective review of case notes from Tri-Service General Hospital archives was performed. Read More

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November 2018
3 Reads

Patterns of failures after surgical resection in olfactory neuroblastoma.

J Neurooncol 2018 Nov 30. Epub 2018 Nov 30.

Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

Introduction: Patterns of failure in patients with olfactory neuroblastoma (ONB) according to two surgical approaches, craniofacial resection (CFR) and endoscopic surgery (ENDO), have yet to be analyzed.

Methods: We retrospectively reviewed 28 patients with surgically treated ONB between January 1995 and October 2017. Fourteen (50. Read More

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November 2018
2 Reads

Results and limits of posterior cranial vault expansion by osteotomy and internal distractors.

Surg Neurol Int 2018 30;9:217. Epub 2018 Oct 30.

Craniofacial Unit, Department of Pediatric Neurosurgery, Hôpital Necker-Enfants Malades, Paris, France.

Background: Expanding the posterior cranial vault has become a common procedure in the treatment of complex craniosynostosis. Several techniques are available to remodel the posterior vault. Aim of this study was to analyze the posterior vault distraction osteogenesis. Read More

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October 2018

The use of flow diverters to treat small (≤5 mm) ruptured, saccular aneurysms.

Surg Neurol Int 2018 30;9:216. Epub 2018 Oct 30.

Neuroradiological Clinic, Neurocenter, Leipzig, Germany.

Background: There is limited published literature on the use of flow diverting stents (FDS) to treat ruptured intracranial aneurysms in the acute stage. We present our experience of using FDS to treat small (≤5 mm) ruptured aneurysms.

Methods: We retrospectively identified all patients with ≤5 mm ruptured aneurysms treated exclusively with FDS between February 2009 and February 2016. Read More

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October 2018

A Case of Seizure Revealing Fahr's Syndrome with Primary Hypoparathyroidism.

Am J Case Rep 2018 Dec 1;19:1430-1433. Epub 2018 Dec 1.

Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.

BACKGROUND Idiopathic basal ganglia calcification, also known as Fahr's disease or Fahr's syndrome, is a rare neurological disorder characterized by abnormal calcified deposits in the basal ganglia. Here, we report a case of Fahr's syndrome with calcification of the basal ganglia due to hypoparathyroidism in a patient with seizures. CASE REPORT A 52-year-old male patient visited our clinic with seizures. Read More

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December 2018

Rivaroxaban Promotes Reduction of Embolus Size within Cerebrocortical Microvessels in a Mouse Model of Embolic Stroke.

Keio J Med 2018 Nov 30. Epub 2018 Nov 30.

Department of Neurology, Keio University School of Medicine, Tokyo, Japan.

Previous reports have suggested that direct oral anticoagulants exert a prothrombolytic effect against intracardiac thrombi. We hypothesized that these anticoagulants may also help recanalize occluded intracranial arteries via prothrombolytic effects. In this study, we evaluated the effects of rivaroxaban, a direct oral anticoagulant, on fibrin emboli within the cerebrocortical microvessels in a mouse model of embolic stroke. Read More

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November 2018

Surgery for very large and giant intracranial aneurysms: Results and complications.

Neurol India 2018 Nov-Dec;66(6):1741-1757

Department of Neurosurgery, University of Washington, Seattle, Washington, USA.

Background: Results of and the complications encountered during surgery for very large and giant intracranial aneurysms are illustrated.

Objective: To analyze a consecutive series of patients with very large and giant aneurysms treated with microsurgery.

Methods: This retrospective study included seventy six very large and giant aneurysms which were managed by clipping and bypass technique. Read More

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December 2018

Microsurgery of giant intracranial aneurysms: Current status.

Neurol India 2018 Nov-Dec;66(6):1614-1616

Department of Neurosurgery and Gamma Knife Radiosurgery, P D Hinduja National Hospital and Medical Research Centre, Mumbai, Maharashtra, India.

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December 2018

Use of quantitative diffusion tensor imaging as a diagnostic tool for intracranial lesions.

Authors:
Aditya Vedantam

Neurol India 2018 Nov-Dec;66(6):1612-1613

Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.

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December 2018
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Genome-wide identification of lncRNAs and mRNAs differentially expressed in non-functioning pituitary adenoma and construction of a lncRNA-mRNA co-expression network.

Biol Open 2018 Nov 30. Epub 2018 Nov 30.

Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou 215000, People's Republic of China

The involvement of long noncoding RNAs (lncRNAs) during tumorigenesis is a recent, emerging theme. Yet, no systematic evaluation of lncRNAs has been previously reported for non-functioning pituitary adenoma (NFPA), a fairly common type of intracranial tumor. Here, we report the first genome-wide expression profile for lncRNAs and mRNAs in NFPA, using formalin-fixed and paraffin-embedded tissue specimens. Read More

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November 2018

Dural arteriovenous fistula mimicking temporal arteritis.

Clin Neurol Neurosurg 2018 Nov 26;176:44-46. Epub 2018 Nov 26.

Department of Neurosurgery, Kuala Lumpur Hospital, Malaysia.

Introduction: Dural arteriovenous fistula (dAVF) is a very rare disease characterized by an abnormal vascular communication between arteries and veins in dural mater. It frequently presents with intracranial haemorrhage. Common presenting symptoms are headache and seizures. Read More

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November 2018

Sudden and unexpected death due to intracranial sellar extramedullary plasmacytoma.

J Forensic Leg Med 2018 Nov 26;61:89-91. Epub 2018 Nov 26.

Institute od Pathology, Faculty of Medicine, Slovak Medical University and Cytopathos Ltd., Limbova 12, 833 03 Bratislava, Slovakia. Electronic address:

The incidence of sudden death caused by undiagnosed primary intracranial neoplasm in young adults is extremely low. The aim of the work is to present a case report of the sudden death of a 24-year-old woman. The autopsy has revealed enlargement of sella turcica with an intrasellar tumorous mass extending into the adjacent basal parts of the brain. Read More

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November 2018
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Associated Injuries Are Frequent and Severe Among Geriatric Patients With Zygomatico-Orbital Fractures.

J Oral Maxillofac Surg 2018 Nov 5. Epub 2018 Nov 5.

Professor, Department of Oral and Maxillofacial Diseases, Institute of Dentistry, University of Turku and Turku University Hospital, Turku, Finland.

Purpose: Associated injuries (AIs) are hypothesized to be frequent in geriatric zygomatico-orbital (ZMO) fractures. The study aim was to determine the relation between ZMO fractures and AIs in geriatric patients compared with younger adult patients.

Patients And Methods: A retrospective case-and-control study was carried out on geriatric patients at least 65 years of age (n = 93) and younger adult patients 20 to 30 years of age (n = 68) diagnosed with pure unilateral ZMO fractures. Read More

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November 2018

Direct Electrical Stimulation of Lateral Orbitofrontal Cortex Acutely Improves Mood in Individuals with Symptoms of Depression.

Curr Biol 2018 Nov 21. Epub 2018 Nov 21.

Weill Institute for Neurosciences, University of California, San Francisco, 675 Nelson Rising Ln, San Francisco, CA 94158, USA; Department of Neurological Surgery, University of California, San Francisco, 400 Parnassus Ave, San Francisco, CA 94143, USA. Electronic address:

Mood disorders cause significant morbidity and mortality, and existing therapies fail 20%-30% of patients. Deep brain stimulation (DBS) is an emerging treatment for refractory mood disorders, but its success depends critically on target selection. DBS focused on known targets within mood-related frontostriatal and limbic circuits has been variably efficacious. Read More

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November 2018
3 Reads

Intraspinal Dissemination and Local Recurrence of an Intracranial Hemangiopericytoma: Case Report.

World Neurosurg 2018 Nov 29. Epub 2018 Nov 29.

Department of Neurosurgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Background: Hemangiopericytomas (HPCs) are rare vascular tumors that resemble meningiomas on imaging and have a high rate of local recurrence and metastases. There remains a paucity of data to guide management decisions of intraspinal dissemination of HPC in the literature, and none specifically related to anaplastic HPCs.

Case Description: Case report of a 34-year-old female with locally and distantly recurrent anaplastic hemangiopericytoma (HPC) (WHO grade III). Read More

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November 2018

Tumour-to-Tumour Metastasis Phenomenon: Metastatic Prostatic Adenocarcinoma within an Anaplastic Oligodendroglioma in the Brain of a Dog.

J Comp Pathol 2018 Nov 29;165:62-66. Epub 2018 Oct 29.

Department of Animal Medicine and Surgery, Veterinary Faculty, Cerdanyola del Vallès, Spain; Networking Research Centre on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.

A 10-year-old entire male French bulldog was presented following clusters of generalized tonic-clonic epileptic seizures. Neurolocalization was consistent with a lesion in the left forebrain. Magnetic resonance imaging of the brain revealed a large, ill-defined, intra-axial, space-occupying lesion at the level of the left temporal and parietal lobes, causing marked compression of the adjacent parenchyma. Read More

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November 2018

Differences in Ischemic Anterior and Posterior Circulation Strokes: A Clinico-Radiological and Outcome Analysis.

J Stroke Cerebrovasc Dis 2018 Nov 27. Epub 2018 Nov 27.

Stroke Center/Neurology Service of the Lausanne University Hospital, Switzerland.

Background: There are limited data comparing posterior (PC) and anterior (AC) circulation acute ischemic strokes (AIS). We aimed to identify specific features of PC and AC strokes regarding clinical, etiological, radiological, and outcome factors.

Methods: Patients from the Acute STroke Registry and Analysis of Lausanne, a prospective cohort of consecutive AIS, from years 2003 to 2008 were included. Read More

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November 2018
1 Read

Mirth and laughter induced by electrical stimulation of the posterior insula.

J Clin Neurosci 2018 Nov 27. Epub 2018 Nov 27.

Beijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.

Laughter induced in the insula is uncommon. In this case-report we present a description of a patient with drug-resistant focal epilepsy for whom laughter with mirth was elicited when the posterior insula (PI) was stimulated by intracranial electrodes. We attempted to analyze the progression of laughter in the insula and suggest a possible pathway for the expression of laughter. Read More

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November 2018

A Child With a Hoarse Cry and Intracranial Calcification.

Pediatr Neurol 2018 Oct 22;87:78-79. Epub 2018 Aug 22.

Dept. of Pediatric Neurology, Childrens Hospital of Michigan, Wayne State University, Detroit, Michigan.

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October 2018

Eliminating the Secret Handshake: A Plea for Clarity in Medical Terminology.

Authors:
E Steve Roach

Pediatr Neurol 2018 Oct 16;87:7-8. Epub 2018 Aug 16.

The University of Texas Dell Medical School, Austin, Texas. Electronic address:

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October 2018