17,189 results match your criteria Intestinal Perforation


Endoscopic closure of gastrointestinal perforations and fistulas using the Ovesco Over-The-Scope Clip system at a tertiary hospital center.

Rev Gastroenterol Mex 2019 Apr 20. Epub 2019 Apr 20.

Unidad de Gastroenterología y Endoscopia Digestiva, Hospital Pablo Tobón Uribe, Medellín, Colombia.

Introduction And Aim: Enteric perforations and fistulas are difficult to manage due to comorbidities, poor nutritional status, and anatomic challenges related to multiple interventions in those patients. The use of endoscopic methods as a nonsurgical approach is increasing. The aim of the present study was to describe the clinical experience with the use of the Ovesco Over-The-Scope Clip system in the closure of perforations, fistulas, and other indications in the digestive tract at a tertiary care hospital center. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rgmx.2018.10.004DOI Listing
April 2019
2 Reads

Ileal perforation caused by a fish bone shortly after drug-eluting stent implantation for acute myocardial infarction.

J Int Med Res 2019 Apr 24:300060519842778. Epub 2019 Apr 24.

1 Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, ZheJiang Province, China.

During the past century, the incidence of myocardial infarction has markedly increased worldwide. Percutaneous coronary intervention with stent implantation is often considered as the first-choice treatment, especially in emergency cases. Current guidelines recommend delayed elective noncardiac surgery for such vulnerable patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0300060519842778DOI Listing

Complications Following Colonoscopy in a Nationwide Standard Cohort: A Retrospective Case-control Study.

Korean J Gastroenterol 2019 Mar;73(3):152-158

, Wonju; Department of Biostatistics, Yonsei University.

Background/aims: Despite the many reports of colonoscopy complications worldwide, few studies have been performed at the population level in Korea. In this study, a population-based study was performed to evaluate the incidence of post-colonoscopy perforations compared to a control group.

Methods: Between January 2011 and December 2011, data for all cases (age over 45) who underwent a colonoscopy were collected from National Health Insurance Service using a random sampling method. Read More

View Article

Download full-text PDF

Source
https://synapse.koreamed.org/DOIx.php?id=10.4166/kjg.2019.73
Publisher Site
http://dx.doi.org/10.4166/kjg.2019.73.3.152DOI Listing
March 2019
1 Read

Surgical Outcomes in Patients with Abdominal Cocoon: Series of 15 Patients.

World J Surg 2019 Apr 22. Epub 2019 Apr 22.

Department of Gastroenterology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Background: Abdominal cocoon (AC) or sclerosing encapsulating peritonitis is an uncommon cause of intestinal obstruction. Surgical intervention is warranted in patients with persistent pain or intestinal obstruction.

Methodology: A retrospective analysis of patients operated for AC was performed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00268-019-05006-xDOI Listing

Expansile Superabsorbent Polymer Ball Foreign Body in the Ear.

J Emerg Med 2019 Apr 17. Epub 2019 Apr 17.

Division of Pediatric Otolaryngology, Department of Otolaryngology- Head and Neck Surgery, UPMC, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.

Background: Superabsorbent polymers (SAPs) are materials that can absorb large quantities of water. Small spherical SAPs are commonly marketed as toys for children.

Case Report: We report the case of a 4-year-old female who presented to a pediatric emergency department with a small, marble-sized SAP that was placed in her ear by herself during the course of play at daycare. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S07364679193012
Publisher Site
http://dx.doi.org/10.1016/j.jemermed.2019.02.016DOI Listing
April 2019
1 Read

Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial.

Lancet Oncol 2019 Apr 16. Epub 2019 Apr 16.

Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy. Electronic address:

Background: Microsatellite-stable metastatic colorectal cancer is typically unresponsive to immunotherapy. This phase 3 study was designed to assess atezolizumab plus cobimetinib in metastatic colorectal cancer. Here, we report the comparison of atezolizumab plus cobimetinib or atezolizumab monotherapy versus regorafenib in the third-line setting. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(19)30027-0DOI Listing

Intestinal Perforation in ACTH-Dependent Cushing's Syndrome.

Biomed Res Int 2019 13;2019:9721781. Epub 2019 Mar 13.

Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.

Previous studies have linked systemic glucocorticoid use with intestinal perforation. However, the association between intestinal perforation and endogenous hypercortisolism has not been well described, with only 14 previously published case reports. In this study, we investigated if intestinal perforation occurred more frequently in patients with ectopic ACTH syndrome and in those with a greater than 10-fold elevation of 24-hour urinary free cortisol level. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/9721781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436364PMC

Gastrointestinal basidiobolomycosis in a patient suffering from duodenal ulcer with perforation: First case report from Italy.

New Microbiol 2019 Apr 17;41(2). Epub 2019 Apr 17.

Institute of Microbiology, Catholic University of the Sacred Heart, Polyclinic University Foundation Agostino Gemelli, IRCCS, Rome, Italy.

Gastrointestinal basidiobolomycosis (GIB), an unusual fungal infection caused by the fungus Basidiobolus ranarum, is rarely reported in the medical literature. GIB is difficult to diagnose because its clinical presentation is non-specific and has no identifiable risk factors. We report here the first case of GIB diagnosed in Italy in a patient suffering from a duodenal ulcer with perforation. Read More

View Article

Download full-text PDF

Source
April 2019
1 Read

Lymphangiomatosis of the ileum with perforation: A case report and review of the literature.

Ann Med Surg (Lond) 2019 May 29;41:6-10. Epub 2019 Mar 29.

Department of Surgery, University of L'Aquila, Italy.

Lymphangiomatosis is a benign proliferation of lymph vessels. Lymphatic diseases can vary from small lymphangioma to generalized lymphangiomatosis, which is a rare condition and can have several clinical manifestations. The gastrointestinal tract may be affected, but the incidence in the intestinal wall is very low. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2019.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449703PMC

Lack of Evidence for Time or Dose Relationship between Antenatal Magnesium Sulfate and Intestinal Injury in Extremely Preterm Neonates.

Neonatology 2019 Apr 9;115(4):371-378. Epub 2019 Apr 9.

Division of Neonatology, Pomona Valley Hospital Medical Center, Pomona, California, USA.

Background: Recent studies reported conflicting results on the relationship between antenatal magnesium sulfate (MgSO4) exposure and neonatal intestinal injury. Most studies have not assessed MgSO4 exposure quantitatively and none reported the exposure timing.

Objectives: The aim of this work was to assess whether there is a temporal or dose-dependent relationship between antenatal MgSO4 exposure and intestinal injury in extremely preterm neonates. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000497412DOI Listing

Unusual case of abdominal fullness in a middle-aged woman.

Gastroenterology 2019 Apr 6. Epub 2019 Apr 6.

Department of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2019.03.062DOI Listing
April 2019
1 Read

Acute appendicitis associated with the presence of schistosome eggs in a sailor: a case report.

Surg Case Rep 2019 Apr 8;5(1):55. Epub 2019 Apr 8.

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki city, Nagasaki, 852-8501, Japan.

Background: Schistosomiasis is prevalent in tropical and subtropical areas and rarely reported in developed countries. Schistosomiasis often occurs as a chronic illness, which can cause liver and intestinal damage. Appendicitis is an unusual complication of schistosomiasis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40792-019-0615-8DOI Listing
April 2019
1 Read

Management of Complications of Colorectal Submucosal Dissection.

Clin Endosc 2019 Mar 29;52(2):114-119. Epub 2019 Mar 29.

Division of Gastroenterology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Endoscopic submucosal dissection (ESD) is a useful procedure for the treatment of superficial gastrointestinal neoplasm. Compared with endoscopic mucosal resection (EMR), ESD has several benefits, which include resectability of various difficult lesion, accurate histologic assessment of specimen, and lower recurrence rate. However, the risk of procedure- related complications is higher with ESD than with EMR. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5946/ce.2019.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453857PMC
March 2019
1 Read

Concomitant fungal peritonitis and high ascitic amylase as a rare manifestation of gastric perforation.

Oxf Med Case Reports 2019 Mar 29;2019(3):omz022. Epub 2019 Mar 29.

Department of Gastroenterology and Hepatology, Al-Mouasat University Hospital, 00963112133000, Damascus, Syria.

High ascitic amylase concentration has been reported to be a characteristic of pancreatic ascites. However, values greater than 2000 U/l can also be seen in intestinal perforation. Fungal peritonitis is a serious entity that could also be caused by hollow viscous perforation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/omcr/omz022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440265PMC
March 2019
2 Reads

Use of contrast-enhanced post-mortem computed tomography to diagnose intestinal perforation caused by malpractice: A case report.

Medicine (Baltimore) 2019 Apr;98(14):e15042

Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai.

Rationale: The application of post-mortem computed tomography (PMCT) and PMCT angiography (PMCTA) is becoming increasingly common in forensic investigations. One of the most frequently applied techniques today is PMCTA. However, few studies have focused on the application of contrast-enhanced PMCT of hollow organs such as the gastrointestinal tract. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000015042DOI Listing
April 2019
2 Reads

The importance of colonoscopy in the treatment of colorectal polyps and colorectal cancer screening.

Ann Ital Chir 2019 Apr 1;8. Epub 2019 Apr 1.

Aim: Colorectal polyp is the most commonly encountered intestinal colon pathology in patients over 50 years of age, and 5% of which develops a "colorectal cancer". The early-stage polyps can be detected and removed endoscopically, which reduce the incidence of carcinoma. Our study is aimed to investigate the role of colonoscopy in colorectal adenoma treatment and screening for colorectal cancers, and to answer the question of whether the colorectal polyps would become malignant or not malignant by means of the comparative analysis of their histological features. Read More

View Article

Download full-text PDF

Source
April 2019
2 Reads

Risk factors associated with clinical outcomes of endoscopic mucosal resection for colorectal laterally spreading tumors: A Honam Association for the Study of Intestinal Diseases (HASID) multicenter study.

Turk J Gastroenterol 2019 Apr;30(4):350-356

Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.

Background/aims: Colorectal laterally spreading tumors (LSTs) are large and superficial neoplasms. Most are adenomatous lesions. Endoscopic mucosal resection (EMR) is a standard technique of removing precursor colorectal lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5152/tjg.2019.18393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453642PMC
April 2019
1 Read

Small intestinal perforation due to a huge gastrointestinal stromal tumor in a kidney transplant recipient: a case report and literature review.

BMC Nephrol 2019 Apr 3;20(1):120. Epub 2019 Apr 3.

Department of Urology, Keio University School of Medicine, Tokyo, 160-8582, Japan.

Background: Gastrointestinal stromal tumors (GISTs) in transplant recipients are very rare and only a handful of cases have been reported to date. Here we present the first known case of a huge GIST in a kidney transplant recipient with perforation of small intestine.

Case Presentation: A 64-year-old male presented at our hospital with right colic pain; he had received an ABO incompatible kidney transplant 6 years earlier and was treated with cyclosporine, mycophenolate mofetil, and methylprednisolone. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12882-019-1310-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448240PMC
April 2019
3 Reads
1.520 Impact Factor

[Advantages of Kasai procedure through minimally invasive approach in children with biliary atresia (in Russian only)].

Khirurgiia (Mosk) 2019 (3):48-59

Pirogov Russian National Research Medical University, Moscow, Russia; Filatov Munitsipal Children's Hospital, Moscow, Russia.

Aim: To compare early and long-term results of different surgical interventions in children with biliary atresia.

Material And Methods: Retrospective analysis included medical records of children with biliary atresia who were treated at the Filatov Munitsipal Children's Hospital and National Medical Research Center for Obstetrics, Gynecology and Perinatology from 2000 to 2018. There were 91 patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17116/hirurgia201903148DOI Listing
January 2019
1 Read

Necrotizing Enterocolitis and Spontaneous Intestinal Perforation: A Spatiotemporal Case Cluster Analysis.

Pediatr Qual Saf 2019 Jan-Feb;4(1):e127. Epub 2019 Jan 4.

Department of Pediatrics, Women & Infants Hospital, Alpert Medical School of Brown University.

Objective: To expand existing statistical methods to identify clusters of necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP) cases in the neonatal intensive care unit.

Methods: In an academic, tertiary referral center, possible NEC or SIP clusters were identified using a binomial distribution scan test. The incidence-density rate (IDR) was calculated as the number of cases per 1,000 patient-days during each possible cluster and compared with the baseline IDR. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/pq9.0000000000000127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426488PMC
January 2019
1 Read

All that fistulises is not Crohn's disease: Multiple entero-enteric fistulae in intestinal tuberculosis.

Pol Przegl Chir 2019 Jan;91(1):35-37

Postgraduate Institute of Medical Education and Research Gastroenterology.

Abdominal tuberculosis is a common problem for clinicians in the tropical world and may manifest with varying clinical scenarios. Intestinal tuberculosis could have intestinal ulcers, strictures, hypertrophic lesions like polyps and may be complicated by perforation, bleeding, and intestinal obstruction. Crohn's disease is an important differential of intestinal tuberculosis which is closely mimics intestinal tuberculosis in clinical, endoscopic, radiological and histological presentation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5604/01.3001.0012.8269DOI Listing
January 2019
1 Read

[An exceptional cause of peritonitis: ileal perforation due to a foreign body during reduction of an inguinal hernia].

Pan Afr Med J 2018 18;31:37. Epub 2018 Sep 18.

Service de Réanimation Médicale CHU Habib Bourguiba Route El Ain, Sfax, Tunisie.

Secondary peritonitis is frequently reported in the literature. It is due to multiple causes. We report an exceptional cause of ileal perforation due to a foreign body during reduction of an inguinal hernia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11604/pamj.2018.31.37.11758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430839PMC
April 2019
2 Reads

The Association between Absence of Abdominal Pain and Mortality in Lower Intestinal Perforation in Patients with Autoimmune Rheumatic Diseases.

Biomed Res Int 2019 17;2019:5381453. Epub 2019 Feb 17.

Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo, Japan.

Objective: To determine mortality and predictive factors for lower intestinal perforation (LIP) among patients with autoimmune rheumatic diseases.

Methods: This retrospective, single-center, observational study analyzed mortality rates in 31 autoimmune rheumatic disease patients with LIP who were admitted to our hospital from January 2002 to June 2017. The primary outcome was the mortality rate during hospitalization. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/5381453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398054PMC
February 2019

Prolonged early antenatal indomethacin exposure is safe for fetus and neonate.

J Matern Fetal Neonatal Med 2019 Apr 4:1-10. Epub 2019 Apr 4.

a Department of Obstetrics, Gynecology and Reproductive Sciences , University of Maryland School of Medicine , Baltimore , MD , USA.

Objective: To evaluate fetal and neonatal safety of early-onset long-term antenatal indomethacin treatment (LIT) for short cervix.

Methods: In this cohort study, women started LIT for short cervix (<25 mm) before completing 25 weeks. They followed a standardized regiment of oral indomethacin: 100 mg loading, 50 mg qid for 48 h, 25 mg qid until delivery or at 32 weeks gestational age (GA), whichever comes first. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14767058.2019.1599351DOI Listing
April 2019
3 Reads

Uncovered versus covered stent in management of large bowel obstruction due to colorectal malignancy: a systematic review and meta-analysis.

Int J Colorectal Dis 2019 May 23;34(5):773-785. Epub 2019 Mar 23.

Department of General Surgery, North Manchester General Hospital, Manchester, M8 5RB, UK.

Purpose: To compare outcomes of uncovered stent and covered stent in management of large bowel obstruction secondary to colorectal malignancy.

Methods: We conducted a search of electronic databases identifying studies comparing outcomes of uncovered and covered stents in management of large bowel obstruction secondary to colorectal malignancy. The Cochrane risk-of-bias tool and the Newcastle-Ottawa scale were used to assess the included studies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00384-019-03277-3DOI Listing
May 2019
1 Read

serovar enteritidis peritonitis with spontaneous intestinal perforation in an immunocompetent patient.

BMJ Case Rep 2019 Mar 20;12(3). Epub 2019 Mar 20.

Hopital d'Instruction des Armees Begin, Saint Mande, France.

Few data reported non-typhoidal peritonitis in immunocompromised patients. We reported the case of a man without immunosuppression or predisposing factor, who developed serovar Enteritidis peritonitis with spontaneous intestinal perforation. After emergent surgery, the patient was transferred to intensive care unit (ICU) because of respiratory, renal and haemodynamic failures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2018-228027DOI Listing
March 2019
1 Read

Nomogram for Predicting Risk of Intestinal Complications After Colorectal Cancer Surgery.

Med Sci Monit 2019 Mar 21;25:2104-2111. Epub 2019 Mar 21.

Department of General Surgery, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China (mainland).

BACKGROUND Intestinal complications are a major cause of morbidity after colorectal cancer surgery. This study aimed to develop an effective nomogram for predicting risk of intestinal complications following colorectal cancer surgery. MATERIAL AND METHODS We retrospectively analyzed 1876 patients who underwent colorectal cancer surgery at Yangpu and Zhuji hospitals from January 2013 to October 2018. Read More

View Article

Download full-text PDF

Source
https://www.medscimonit.com/abstract/index/idArt/915692
Publisher Site
http://dx.doi.org/10.12659/MSM.915692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439933PMC
March 2019
9 Reads

Differentiation between stercoral perforation and colorectal cancer perforation.

Rev Assoc Med Bras (1992) 2019 Feb;65(2):191-197

Department of Radiology, Soonchunhyang University Seoul Hospital, Yongsan-gu, Seoul, Korea.

Objective: To determine the computed tomography (CT) signs associated with stercoral perforation and colorectal cancer perforation.

Materials And Methods: From May 2003 to Feb. 2015, all surgically and pathologically confirmed patients with stercoral perforation (n=8, mean age 68. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/1806-9282.65.2.191DOI Listing
February 2019
1 Read

A Toothpick a day, keeps the doctor away?

Acta Gastroenterol Belg 2019 Jan-Mar;82(1):97-98

Department of Gastro-enterology, AZ-Groeninge, Kortrijk, Belgium.

A Toothpick is a dreaded offender when ingested, as it is risky to cause impaction, obstruction or perforation of the gut. When ingestion of a toothpick leads to one of these complications, it clinically mimics an acute abdomen. Often the patient doesn't recall the ingestion, leading to misdiagnosis as inflammatory bowel disease, appendicitis/diverticulitis, etc. Read More

View Article

Download full-text PDF

Source
March 2019
1 Read

Endoloop ligation after endoscopic mucosal resection using a transparent cap: A novel method to treat small rectal carcinoid tumors.

World J Gastroenterol 2019 Mar;25(10):1259-1265

Department of Gastroenterology, Shenzhen People's Hospital, First Affiliated Hospital of Southern University of Science and Technology, Second Clinical Medical College of Jinan University, Shenzhen 518020, Guangdong Province, China.

Background: Local endoscopic resection is an effective method for the treatment of small rectal carcinoid tumors, but remnant tumor at the margin after resection remains to be an issue.

Aim: To evaluate the efficacy and safety of resection of small rectal carcinoid tumors by endoloop ligation after cap-endoscopic mucosal resection (LC-EMR) using a transparent cap.

Methods: Thirty-four patients with rectal carcinoid tumors of less than 10 mm in diameter were treated by LC-EMR ( = 22) or endoscopic submucosal dissection (ESD) ( = 12) between January 2016 and December 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3748/wjg.v25.i10.1259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421235PMC
March 2019
4 Reads

Nationwide observational study of mortality from complicated intra-abdominal infections and the role of bacterial cultures.

Br J Surg 2019 Apr 18;106(5):606-615. Epub 2019 Mar 18.

Department of Health Policy and Informatics, Tokyo Medical and Dental University, Tokyo, Japan.

Background: The benefit of taking intra-abdominal cultures during source control procedures in patients with complicated intra-abdominal infection (CIAI) is unknown. The aim of this study was to evaluate whether intra-abdominal cultures reduce the mortality rate of CIAI.

Methods: The Japanese Diagnosis Procedure Combination database was used to identify adult patients with CIAI who had undergone source control procedures on the first day of admission to hospital between April 2014 and March 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bjs.11095DOI Listing
April 2019
1 Read

Primary gastrointestinal aspergillosis: a case report and literature review.

Infez Med 2019 Mar;27(1):85-92

Medipol University, Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Istanbul, Turkey.

Invasive aspergillosis is a severe infection that generally involves the lungs. Primary gastrointestinal aspergillosis is the least common form of invasive aspergillosis. A patient aged 65 years developed a febrile neutropenic episode following an autologous stem cell transplant for plasmacytoid variant diffuse large B-cell gastric non-Hodgkin's lymphoma. Read More

View Article

Download full-text PDF

Source
March 2019
1 Read

Small bowel perforation with multiple intestinal metastases from lung carcinoma: A case report.

Oncol Lett 2019 Apr 12;17(4):3862-3866. Epub 2019 Feb 12.

3rd Department of Surgery, National and Kapodistrian University of Athens, School of Medicine, Attikon Hospital, Athens 12462, Greece.

The present report describes the case of an 81-year-old woman who underwent an emergency explorative laparotomy due to small bowel perforation. Diffuse feculent peritonitis due to perforation of the jejunum was identified. In addition, six distinct tumors of the jejunum in close proximity to the perforation site, as well as two more lesions caudally at the ileum, were identified. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ol.2019.10031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403519PMC
April 2019
2 Reads

STING-mediated intestinal barrier dysfunction contributes to lethal sepsis.

EBioMedicine 2019 Mar 14;41:497-508. Epub 2019 Mar 14.

Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China. Electronic address:

Background: Gut integrity is compromised in abdominal sepsis with increased cellular apoptosis and altered barrier permeability. Intestinal epithelial cells (IEC) form a physiochemical barrier that separates the intestinal lumen from the host's internal milieu and is strongly involved in the mucosal inflammatory response and immune response. Recent research indicates the involvement of the stimulator of interferons genes (STING) pathway in uncontrolled inflammation and gut mucosal immune response. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2019.02.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443583PMC
March 2019
4 Reads

[Small bowel perforation caused by intestinal dissemination of pulmonary tuberculosis due to biological therapy].

Magy Seb 2019 Mar;72(1):13-19

Általános Sebészeti Osztály, Szent Pantaleon Kórház - Rendelőintézet Dunaújváros 2400 Dunaújváros, Korányi Sándor u. 4-6.

Case review: The authors present a case of a 78-year-old female patient who previously, as a teenager, had been treated for pulmonary tuberculosis. The biological therapy for subsequent inflammatory bowel disease in 2015 caused a flare up of the respiratory symptoms after 60 years of being asymptomatic, and the patient also developed acute abdomen. She required emergency laparotomy and small intestine segment resection was performed due to perforated ileum. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1556/1046.72.2019.1.3DOI Listing
March 2019
1 Read

Tension Pneumoperitoneum: A Rare Presentation Of Megacystis Microcolon Intestinal Hypoperistalsis Syndrome.

J Ayub Med Coll Abbottabad 2019 Jan-Mar;31(1):136-137

Department of Radiology, Shifa International Hospital, Islamabad, Pakistan.

Megacystis microcolon intestinal hypoperistalsis syndrome also known as Berdon syndrome is characterized by enlarged urinary bladder, small colon and reduced or absent intestinal peristalsis. We report a case of 4 days old female suffering from MMIHS presenting with tension pneumoperitoneum. To the best of our knowledge, this is the first reported case of MMIHS, having this unusual presentation. Read More

View Article

Download full-text PDF

Source

Malakoplakia of the colon following renal transplantation in a 73 year old woman: report of a case presenting as intestinal perforation.

Diagn Pathol 2019 Mar 13;14(1):22. Epub 2019 Mar 13.

Department of Radiology, Maisonneuve-Rosemont Hospital, 5415 Boulevard de L'Assomption, Montreal, QC, Canada.

Background: Malakoplakia is a chronic inflammatory disease characterized by tissue infiltrates of large granular macrophages containing distinctive intracytoplasmic inclusions termed Michaelis-Gutmann (MG) bodies. The genitourinary system is the most commonly involved site, followed by the gastrointestinal tract. Malakoplakia may occur as a complication of primary or secondary immunosuppression and, therefore, renal transplant recipients are at risk. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13000-019-0799-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416959PMC
March 2019
2 Reads

Small bowel strictures.

Curr Opin Gastroenterol 2019 May;35(3):235-242

AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, RPA Medical Centre, Camperdown, Sydney, New South Wales, Australia.

Purpose Of Review: Strictures of the small bowel are an underdiagnosed entity with significant morbidity because of obstruction and risk of perforation and penetrating disease.

Recent Findings: Recent advances in imaging, enteroscopy, and therapeutic advances particularly in Crohn's disease have enabled gastroenterologists to target and individualize management of small bowel strictures, preventing untimely surgery and complications.

Summary: All patients with obstructive symptoms, suspected small bowel disease, and negative panendoscopy should be evaluated for small intestinal strictures with cross-sectional imaging and considered for capsule endoscopy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOG.0000000000000531DOI Listing
May 2019
6 Reads

Single-Incision Laparoscopic Repair for Iatrogenic Duodenal Injury in Children with Choledochal Cysts.

J Laparoendosc Adv Surg Tech A 2019 Mar 13. Epub 2019 Mar 13.

1 Department of Pediatric Surgery, Capital Institute of Pediatrics, Beijing, P.R. China.

Background/purpose: During laparoscopic excision of choledochal cysts (CDCs), if duodenum injury is encountered, conversion to open repair of duodenal injury is often the standard approach. This study evaluates if it is safe to repair the duodenal injury laparoscopically in CDC children.

Materials And Methods: CDC children who underwent single-incision laparoscopic repair for iatrogenic duodenal injury between October 2013 and September 2018 were reviewed. Read More

View Article

Download full-text PDF

Source
https://www.liebertpub.com/doi/10.1089/lap.2018.0692
Publisher Site
http://dx.doi.org/10.1089/lap.2018.0692DOI Listing
March 2019
7 Reads

Spontaneous perforation of small intestine followed by rupture of the cystic artery: the natural history of Vascular Ehlers-Danlos Syndrome.

Autops Case Rep 2019 Jan-Mar;9(1):e2018054. Epub 2019 Jan 17.

Mount Sinai Medical Center, AM Rywlin MD Department of Pathology and Laboratory Medicine. Miami Beach, FL, United States of America.

Vascular Ehlers-Danlos Syndrome (VEDS) is a rare autosomal dominant disorder caused by mutations in the or genes. Its mortality is secondary to sudden and spontaneous rupture of arteries or hollow organs. The genotype influences the distribution of arterial pathology with aneurysms of intra-abdominal visceral arteries being relatively uncommon. Read More

View Article

Download full-text PDF

Source
http://www.autopsyandcasereports.org/article/doi/10.4322/acr
Publisher Site
http://dx.doi.org/10.4322/acr.2018.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394365PMC
January 2019
8 Reads

Severe ileocecal inflammatory syndrome in adult patients with cystic fibrosis.

Z Gastroenterol 2019 Mar 12;57(3):312-316. Epub 2019 Mar 12.

University Hospital Leipzig, Division of Gastroenterology, Leipzig, Germany.

The relevance of gastrointestinal manifestations of cystic fibrosis (CF) is increasing due to an improved life expectancy. We report on 2 adult patients with prior lung transplantation who presented with a severe inflammatory disorder of the ileocecal region. One patient underwent ileocecal resection; the second patient died after emergency surgery for intestinal perforation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/a-0829-7050DOI Listing
March 2019
1 Read
1.671 Impact Factor

A Novel Mouse Model of Sporadic Colon Cancer Induced by Combination of Conditional Apc Genes and Chemical Carcinogen in the Absence of Cre Recombinase.

Carcinogenesis 2019 Mar 12. Epub 2019 Mar 12.

Department of Radiology, The University of Chicago, Chicago, Illinois, USA.

Although valuable insights into colon cancer biology have been garnered from human colon cancer cell lines and primary colonic tissues, and animal studies using human colon cancer xenografts, immunocompetent mouse models of spontaneous or chemically-induced colon cancer better phenocopy human disease. As most sporadic human colon tumors present adenomatous polyposis coli (APC) gene mutations, considerable effort has gone into developing mice that express mutant Apc alleles that mimic human colon cancer pathogenesis. A serious limitation of many of these Apc-mutant murine models, however, is that these mice develop numerous tumors in the small intestine but few, if any, in the colon. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgz050DOI Listing

Hypocalcemia Revealing an Enteropathy-Associated T-cell Lymphoma.

Caspian J Intern Med 2019 ;10(1):111-117

Department of Internal Medicine, Gran Canaria University Hospital, Las Palmas, Spain.

Background: Enteropathy-associated T-cell lymphoma (EATL) is a rare and aggressive type of extranodal T-cell lymphoma (TCL) arising in the gastrointestinal (GI) tract and represents 5-8% of all T-cell non-Hodgkin lymphomas (NHL) and 10-25% of primary intestinal lymphomas.

Case Presentation: We reported a 78-year-old woman presenting with severe hypocalcemia. Investigations confirmed vitamin D and iron deficiency as well as hypoalbuminemia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.22088/cjim.10.1.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386331PMC
January 2019
5 Reads

Necrosis of the small intestine leading to a diagnosis of polyarteritis nodosa: a case report.

J Med Case Rep 2019 Mar 9;13(1):55. Epub 2019 Mar 9.

Department of Pathology, Saitama Medical University, 38 Morohongou, Moroyama, Iruma-gun, Saitama, 350-0495, Japan.

Background: Polyarteritis nodosa is a disease that presents with necrotizing vasculitis in small and medium-sized arteries. It may occur in various organs, but approximately half of cases have gastrointestinal involvement. Prognosis is not favorable once organ dysfunction begins as evidenced by gastrointestinal symptoms; thus, treatment with steroids should be promptly initiated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13256-019-2017-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408775PMC
March 2019
1 Read

Using formalin fixed paraffin embedded tissue to characterize the preterm gut microbiota in necrotising enterocolitis and spontaneous isolated perforation using marginal and diseased tissue.

BMC Microbiol 2019 Mar 4;19(1):52. Epub 2019 Mar 4.

Section of Neonatology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.

Background: Necrotising enterocolitis (NEC) is a common cause of death in preterm infants and is closely linked to the gut microbiota. Spontaneous intestinal perforation (SIP) also occurs in preterm neonates, but results in lower mortality and less adverse neonatal outcomes than NEC. Existing studies are largely limited to non-invasive stool samples, which may not be reflective of the anatomical site of disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12866-019-1426-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398254PMC
March 2019
3 Reads

Impact of practice change on intestinal perforation risk for pediatric gastrojejunostomy tube placement.

J Pediatr Surg 2019 Feb 6. Epub 2019 Feb 6.

Section of Pediatric Surgery, Department of Surgery, University of Michigan Medical School and C.S. Mott Children's Hospital, Ann Arbor, Michigan.

Background: Gastrojejunostomy tubes (GJTs) have been associated with intestinal perforation in children <6 months or <6 kg. This study evaluated the impact of an institutional practice change recommending a new soft tip GJT for children <10 kg.

Methods: We performed a single-center review of GJT placements among children <10 kg before (1/1/2010-12/31/2013) and after (7/1/2014-12/31/2016) the practice change. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00223468193008
Publisher Site
http://dx.doi.org/10.1016/j.jpedsurg.2019.01.043DOI Listing
February 2019
8 Reads

Successful closure of ileostomy in a patient with intestinal Behçet's disease after therapy with adalimumab: A case report.

Medicine (Baltimore) 2019 Mar;98(9):e14624

Department of Rheumatology and Immunology.

Rationale: Behçet's disease (BD) is a chronic immune-mediated inflammatory disorder involving multiple organ systems. In BD, intestinal ulcers can present as a refractory lesion capable of perforation, which makes the choice of treatment difficult.

Patient Concerns: A 34-year-old male who was diagnosed with intestinal BD and suffered with an ileocecal perforation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000014624DOI Listing
March 2019
1 Read