17,081 results match your criteria Intestinal Perforation


Non-occlusive intestinal ischemia in the ascending colon and rectum: a pediatric case occurring during encephalitis treatment.

Surg Case Rep 2019 Feb 15;5(1):23. Epub 2019 Feb 15.

Department of Pediatrics, Yamanashi Prefectural Central Hospital, Kofu, Japan.

Background: Non-occlusive mesenteric ischemia (NOMI) is a rare and severe pathological condition that can cause intestinal necrosis without mechanical obstruction of the mesenteric artery. NOMI often develops during the treatment of severe disease in elderly patients and mostly occurs in the intestine supplied by the superior mesenteric artery (SMA). We experienced a 12-year-old patient with NOMI that was segmentally localized in the ascending colon and rectum during encephalitis treatment. Read More

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http://dx.doi.org/10.1186/s40792-019-0592-yDOI Listing
February 2019

Atraumatic splenic rupture secondary to appendicular perforation by cecal volvulus.

Cir Cir 2019 ;87(2):211-214

Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Tenerife, España.

Atraumatic splenic rupture, an infrequent surgical emergency, constitutes a life-threatening situation. The lack of a traumatic background makes it difficult to suspect. We present a case of a 45-year-old woman, with history of bariatric surgery, referred to our emergency due to 3 weeks long abdominal and lumbar pain, in shock. Read More

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http://dx.doi.org/10.24875/CIRU.18000373DOI Listing
January 2019

[A Case of Diverticular Perforation of Sigmoid Colostomy during FOLFIRI plus BevacizumabTreatment].

Gan To Kagaku Ryoho 2019 Jan;46(1):148-150

Dept. of Surgery, Toda Chuo General Hospital.

A 61-year-old man with a diagnosis of rectal cancer underwent assisted laparoscopic rectal amputation. Recurrence occurred, and treatment with FOLFIRI plus bevacizumab was initiated at our department. After 12 treatment courses, he developed abdominal pain at home. Read More

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January 2019

A Case Against Fancy Decorated Drinks: Multi-Organ Failure After Drinking a Mojito Cocktail.

Eur J Case Rep Intern Med 2016 6;3(6):000479. Epub 2016 Sep 6.

Department of Internal Medicine and Gastroenterology, Albert Schweitzer Hospital, Dordrecht, The Netherlands.

We present the first case of gastro-intestinal perforation caused by a mint twig decorating a cocktail drink. A 76-year-old man was enjoying his Mojito cocktail on a cruise ship near Mexico when he accidently swallowed a mint twig, resulting in ileum perforation. This led to a cascade of events, eventually resulting in life-threatening multi-organ failure. Read More

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http://dx.doi.org/10.12890/2016_000479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346844PMC
September 2016

Acquired diverticular disease of the jejunum and ileum: imaging features and pitfalls.

Abdom Radiol (NY) 2019 Feb 13. Epub 2019 Feb 13.

Department of Radiology, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75674, Paris, France.

Purpose: To present radiological aspects of jejunoileal diverticulosis and its complications.

Results: Jejunoileal diverticulosis is a relatively rare and underestimated condition, which mostly affects the elderly. It is frequently asymptomatic but it can lead to significant complications requiring surgical treatment. Read More

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http://dx.doi.org/10.1007/s00261-019-01928-1DOI Listing
February 2019

A Rare Presentation of Small Bowel Diverticulosis Causing Chronic Obstruction and Malnutrition: A Case Study with Review of Literature.

Case Rep Surg 2019 13;2019:2548631. Epub 2019 Jan 13.

National Hospital of Sri Lanka, Sri Lanka.

Small bowel diverticulosis is an uncommon entity. Clinical presentation of small intestinal diverticulosis is variable. A high mortality is associated with complications such as chronic malnutrition, haemorrhage, intestinal obstruction, and perforation. Read More

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http://dx.doi.org/10.1155/2019/2548631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348891PMC
January 2019

[Chilaiditi sign and differential diagnosis with intestinal perforation].

Rev Esp Geriatr Gerontol 2019 Feb 9. Epub 2019 Feb 9.

Unidad de Convalecencia, Centro Sociosanitario Albada, Corporación Sanitaria ParcTaulí, Sabadell, Barcelona, España.

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http://dx.doi.org/10.1016/j.regg.2018.11.004DOI Listing
February 2019

Endoscopic vacuum assisted wound closure (EVAC) device to treat esophageal and gastric leaks: assessing time to proficiency and cost.

Surg Endosc 2019 Feb 11. Epub 2019 Feb 11.

Department of Minimally Invasive Surgery, Baylor University Medical Center, Dallas, TX, USA.

Background: Endoluminal vacuum therapy (EVAC) is an emerging procedure used to treat anastomotic leaks and/or perforations that would otherwise require surgery. The aim of this study was to determine time to proficiency in EVAC and the cost effectiveness of the procedure.

Methods: We retrospectively reviewed a prospectively maintained IRB approved database for all patients undergoing EVAC after esophageal and gastric complications between October 2013 and December 2017. Read More

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http://dx.doi.org/10.1007/s00464-019-06685-2DOI Listing
February 2019

Prolonged duration of early antibiotic therapy in extremely premature infants.

Pediatr Res 2019 Jan 22. Epub 2019 Jan 22.

Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.

Background: Prolonged early antibiotics in extremely premature infants may have negative effects. We aimed to assess prevalence and outcomes of provision of prolonged early antibiotics to extremely premature infants in the absence of culture-confirmed infection or NEC.

Methods: Cohort study of infants from 13 centers born without a major birth defect from 2008-2014 who were 401-1000 grams birth weight, 22-28 weeks gestation, and survived ≥5 days without culture-confirmed infection, NEC, or spontaneous intestinal perforation. Read More

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http://dx.doi.org/10.1038/s41390-019-0300-4DOI Listing
January 2019

Connexin-43-dependent ATP release mediates macrophage activation during sepsis.

Elife 2019 Feb 8;8. Epub 2019 Feb 8.

Department for BioMedical Research, University of Bern, Bern, Switzerland.

Bacterial spillage into a sterile environment following intestinal hollow-organ perforation leads to peritonitis and fulminant sepsis. Outcome of sepsis critically depends on macrophage activation by extracellular ATP-release and associated autocrine signaling via purinergic receptors. ATP-release mechanisms, however, are poorly understood. Read More

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http://dx.doi.org/10.7554/eLife.42670DOI Listing
February 2019
1 Read

Complications of Long-Term Indwelling Transmural Double Pigtail Stent Placement for Symptomatic Peripancreatic Fluid Collections.

Dig Dis Sci 2019 Feb 6. Epub 2019 Feb 6.

Department of Gastroenterology, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0375, Japan.

Background: Endoscopic transmural drainage is performed for symptomatic peripancreatic fluid collections (PPFCs). Long-term transmural double-pigtail stent (DPS) placement is useful in preventing recurrences. There are few reports on the long-term safety of DPS placement. Read More

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http://dx.doi.org/10.1007/s10620-019-05508-7DOI Listing
February 2019
1 Read

Outcome and risk factors associated with perirenal subcapsular fluid collections in extremely preterm infants with acute kidney injury.

Eur Radiol 2019 Feb 4. Epub 2019 Feb 4.

Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, Republic of Korea, 06351.

Objectives: To investigate the incidence of, clinical outcome of, and risk factors for perirenal subcapsular fluid collections in extremely preterm infants with acute kidney injury (AKI).

Methods: Extremely preterm infants with AKI who underwent renal ultrasonography (US) during neonatal intensive care unit stay were classified into two groups according to the presence of a perirenal subcapsular fluid collection at US. Clinical outcome was compared, and relevant data were analysed, including demographics and comorbidities of the infants, as well as maternal demographics. Read More

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http://link.springer.com/10.1007/s00330-018-5962-5
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http://dx.doi.org/10.1007/s00330-018-5962-5DOI Listing
February 2019
3 Reads

A Catastrophic Case of Idiopathic Cholesterol Crystal Embolism with Multiple Lethal Complications: A Labyrinth Underneath the Diagnosis of Skin Ulcers in Chronic Kidney Disease Patients.

Intern Med 2019 Feb 1. Epub 2019 Feb 1.

Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Japan.

A 66-year-old man was admitted to our hospital because of multiple refractory skin ulcers. Based on his severe systemic arterial calcification and severe calcium-phosphate imbalance due to severe kidney dysfunction, we initially considered calciphylaxis. However, a skin biopsy provided a diagnosis of cholesterol crystal embolization. Read More

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http://dx.doi.org/10.2169/internalmedicine.2378-18DOI Listing
February 2019
1 Read

Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer.

BMJ Case Rep 2019 Jan 29;12(1). Epub 2019 Jan 29.

Department of General Surgery, Ministry of Health, Dammam, Eastern Province, Saudi Arabia.

Basidiobolomycosis is a rare fungal infection that may affect the gastrointestinal tract. It is caused by and less than 80 cases have been reported in the literature. The incidence seems to be higher in the Middle East and in particular Saudi Arabia where most cases are diagnosed in the south-western region. Read More

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http://dx.doi.org/10.1136/bcr-2018-225054DOI Listing
January 2019
2 Reads

Perforation of Cecal Diverticulum after Appendectomy.

Authors:
Kesici Ugur

J Coll Physicians Surg Pak 2019 Feb;29(2):175-177

Department of General Surgery, Faculty of Medicine, University of Beykent, Istanbul, Turkey.

Solitary cecal diverticulum was first described by Potier in 1912. Although it is a rare condition, however, there is an increased prevalence in Asian populations. The cecal diverticula are usually asymptomatic, however, 10-20% of the cases become symptomatic due to complications. Read More

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http://dx.doi.org/10.29271/jcpsp.2019.02.175DOI Listing
February 2019
1 Read

Chirurgische Behandlung der chronisch entzündlichen Darmerkrankungen.

Ther Umsch 2019 Jan;75(5):302-314

1 Klinik für Viszeralchirurgie, Universitätsspital Lausanne CHUV.

Surgical treatment of chronic inflammatory bowel disease Abstract. Surgery is an important mainstay in the treatment of inflammatory bowel disease. Despite considerable progress in anti-inflammatory treatment approaches, two thirds of patients with Crohn's Disease will need surgery during their lifetime. Read More

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http://dx.doi.org/10.1024/0040-5930/a001001DOI Listing
January 2019
1 Read

Case 4-2019: An 18-Year-Old Man with Abdominal Pain and Hematochezia.

N Engl J Med 2019 Jan;380(5):473-485

From the Department of Medicine, Brigham and Women's Hospital (H.M.S.), the Departments of Medicine (F.J.S., K.L.A.), Radiology (T.T.P.), Surgery (M.F.C., M.G.R.), and Orthopedic Surgery (S.D.M.), Massachusetts General Hospital, and the Departments of Medicine (H.M.S., F.J.S., K.L.A.), Radiology (T.T.P.), Surgery (M.F.C., M.G.R.), and Orthopedic Surgery (S.D.M.), Harvard Medical School - all in Boston.

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http://www.nejm.org/doi/10.1056/NEJMcpc1810391
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http://dx.doi.org/10.1056/NEJMcpc1810391DOI Listing
January 2019
9 Reads

Perforation of Meckel's diverticulum by a swallowed fish bone: case report and literature review.

J Surg Case Rep 2019 Jan 24;2019(1):rjz003. Epub 2019 Jan 24.

Department of Surgery, Centro Hospitalar do Porto, 4099-001 Porto, Portugal.

Meckel's diverticulum is the commonest congenital abnormality of the gastrointestinal tract. Most cases are asymptomatic and only incidentally found. Its perforation by a foreign body is an extremely rare event. Read More

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http://dx.doi.org/10.1093/jscr/rjz003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344916PMC
January 2019
1 Read

[A Case of Emergency Surgery for Intussusception Due to Cecal Cancer].

Gan To Kagaku Ryoho 2018 Dec;45(13):2387-2389

Dept. of Surgery, Fuchu Hospital.

A 79-year-old woman was admitted to the hospital because of continuous right lower abdominal pain lasting for 1 day. There was tenderness with signs of peritoneal irritation at the right lower abdomen along with a palpable mass. With the diagnosis of intussusception of the ileocecal region by CT examination, an emergency surgery was performed under general anesthesia. Read More

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December 2018
2 Reads

[A Case of Intestinal Perforation Due to a Catheter for Intraperitoneal Access Port for Intraperitoneal Chemotherapy for Gastric Cancer].

Gan To Kagaku Ryoho 2018 Dec;45(13):2381-2383

Dept. of Surgery, Faculty of Medicine, Kindai University.

The usefulness of intraperitoneal(IP)chemotherapy for gastric cancer with intraperitoneal metastasis has been examined in some clinical trials. We report a case of intestinal perforation caused by a catheter for IP ports. A 75-year-old man had undergone IP therapy for type 4 gastric cancer. Read More

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December 2018

Traumatic Rupture of Jejunal Burkitt's Lymphoma with Intestinal Transection.

J Indian Assoc Pediatr Surg 2019 Jan-Mar;24(1):61-62

Department of Pediatric Surgery, Sardar Patel Medical College and Associated Group of Hospitals, Bikaner, Rajasthan, India.

Burkitt's lymphoma (BL) is an aggressive non-Hodgkin lymphoma.[1] BL of the small intestine, presenting as a surgical emergency needing emergency laparotomy, is an uncommon presentation of this tumor. We present a case of BL presenting as perforation peritonitis after blunt trauma abdomen. Read More

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http://dx.doi.org/10.4103/jiaps.JIAPS_67_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322174PMC
January 2019
1 Read

Intraperitoneal alpha-emitting radio immunotherapy with Astatine-211 in relapsed ovarian cancer; long-term follow-up with individual absorbed dose estimations.

J Nucl Med 2019 Jan 25. Epub 2019 Jan 25.

Clinical Sciences, University of Gothenburg, Sweden.

Eliminating microscopic residual disease with α-particle radiation is theoretically appealing. Following extensive preclinical work with α-particle emitting astatine-211 (At), we performed a phase I trial with intraperitoneal (i.p. Read More

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http://dx.doi.org/10.2967/jnumed.118.220384DOI Listing
January 2019

Intestinal perforation after liposuction.

Cir Esp 2019 Jan 22. Epub 2019 Jan 22.

Servicio de Cirugía General, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.

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http://dx.doi.org/10.1016/j.ciresp.2018.12.006DOI Listing
January 2019

Chronic nodules of sigmoid perforation caused by incarcerated intrauterine contraception device.

Medicine (Baltimore) 2019 Jan;98(4):e14117

Department of Gynecology, Guangdong Women and Children Hospital.

Rationale: It is extremely rare for an intrauterine contraception device (IUD) to cause uterine perforation and Sigmoid perforation for a long time without being detected.

Patient Concerns: We present a case of a patient who has suffered from abdominal pain after 4 years of placement of an IUD, and found that the IUD was incarcerated by ultrasound.

Diagnoses: Laparoscopic and hysteroscopic examination revealed that the incarcerated IUD caused uterine perforation and sigmoid perforation for a long time. Read More

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http://dx.doi.org/10.1097/MD.0000000000014117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358395PMC
January 2019
1 Read

Rectal ulcer due to Kayexalate deposition - an unusual case.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):680-683

. Internal Medicine Department, Medicine Service III - Santarém Hospital - Santarém, Santarém, Portugal.

Sodium polystyrene sulfonate (PSP) or Kayexalate is a cation-exchange resin, widely used in the management of hyperkalaemia due to renal disease. A rare, yet potentially dangerous, adverse event related to sodium polystyrene sulfonate use is intestinal mucosal injury, especially in the colon. The injury to the gastrointestinal mucosa can range from mild and superficial to wall necrosis and bowel perforation. Read More

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http://dx.doi.org/10.1590/1806-9282.64.08.680DOI Listing
August 2018
3 Reads

The use of bedside echocardiography for measuring cardiac index and systemic vascular resistance in pediatric patients with septic shock.

Rev Bras Ter Intensiva 2018 Oct-Dec;30(4):460-470

Department of Pediatrics, Faculty of Medicine, Cairo University - Cairo, Egypt.

Objective: Follow-up of cardiac index and systemic vascular resistance index by bedside echocardiography until resuscitation.

Methods: A set of hemodynamic parameters was obtained, including cardiac output, stroke volume, cardiac index, systemic vascular resistance index, velocity time integral, myocardial performance index, capillary refill time, and heart rate at 0 hours after fluid boluses before the start of inotropes, and followed up after 6 hours and 24 hours.

Results: Included were 45 patients with community-acquired septic shock. Read More

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http://dx.doi.org/10.5935/0103-507X.20180067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334480PMC
April 2018
2 Reads

Acute ischemic intestinal necrosis as a rare side effect of nilotinib.

Authors:
L Li W Liu Z Zeng S Chen

Niger J Clin Pract 2019 Jan;22(1):131-133

Collaborative Innovation Center of Hematology, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, The First Affiliated Hospital of Soochow University, Suzhou, China.

Tyrosine kinase inhibitors (TKIs) are highly effective therapies for chronic myeloid leukemia (CML). However, continuous administration of TKIs could lead to toxicity that could induce serious vascular disorders. Nilotinib, a second-generation TKI, has been approved for patients with CML in the chronic phase or accelerated phase, after resistance to imatinib has been identified, or as a first-line treatment. Read More

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http://dx.doi.org/10.4103/njcp.njcp_33_18DOI Listing
January 2019
1 Read

Pediatric Endoscopy and High Risk Patients: A Clinical Report from the NASPGHAN Endoscopy Committee.

J Pediatr Gastroenterol Nutr 2019 Jan 16. Epub 2019 Jan 16.

Texas Children's Hospital, 1010 MW Tower, 6621 Fannin St, Houston, TX 77030.

Pediatric gastrointestinal endoscopy has been established as safe and effective for diagnosis and management of many pediatric gastrointestinal diseases. Nevertheless, certain patient and procedure factors should be recognized that increase the risk of intra and/or post procedural adverse events. Adverse events associated with endoscopic procedures can broadly be categorized as involving sedation-related physiological changes, bleeding, perforation and infection. Read More

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http://dx.doi.org/10.1097/MPG.0000000000002277DOI Listing
January 2019
5 Reads

Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms.

Gut 2019 Jan 19. Epub 2019 Jan 19.

Medical Department 1, University Hospital Dresden, Technische Universität Dresden (TU Dresden), Dresden, Germany.

Objective: Diverticular disease is a common complex disorder characterised by mucosal outpouchings of the colonic wall that manifests through complications such as diverticulitis, perforation and bleeding. We report the to date largest genome-wide association study (GWAS) to identify genetic risk factors for diverticular disease.

Design: Discovery GWAS analysis was performed on UK Biobank imputed genotypes using 31 964 cases and 419 135 controls of European descent. Read More

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2018-317619
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http://dx.doi.org/10.1136/gutjnl-2018-317619DOI Listing
January 2019
5 Reads

Intestinal Perforation Secondary to Pits of Jujube Ingestion: A Single-Center Experience with 18 Cases.

World J Surg 2019 Jan 18. Epub 2019 Jan 18.

Department of General Surgery, Peking University Third Hospital, Beijing, 100191, China.

Background: Ingestion of jujube pits is a common clinical problem, which can be difficult to diagnose and life-threatening if accompanied with intestinal perforation and peritonitis. In this study, 18 cases of intestinal perforation caused by ingestion of jujube pits were reviewed and summarized to discuss the clinical characteristics, diagnosis and treatments.

Methods: From 2012 to 2018, a total of 18 patients diagnosed as intestinal perforation due to ingested pits of jujube in our center were retrospectively reviewed and the manifestations, laboratory tests, imaging examinations and treatment strategies were summarized. Read More

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http://dx.doi.org/10.1007/s00268-018-04902-yDOI Listing
January 2019
3 Reads

Fragility of Life: Recurrent Intestinal Perforation Due to Vascular Ehlers-Danlos Syndrome.

Dig Dis Sci 2019 Jan 17. Epub 2019 Jan 17.

Division of Colorectal Surgery, Department of General Surgery, Stanford University School of Medicine, 300 Pasteur Drive Rm H3691, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1007/s10620-019-5467-3DOI Listing
January 2019
1 Read

Correlation between a continent ileocecal valve and CT signs of severity in patients presenting with obstructive colonic cancer.

Emerg Radiol 2019 Jan 18. Epub 2019 Jan 18.

Department of Radiology, Besançon University Hospital, 3 boulevard Fleming, 25030, Besançon, France.

Objective: To study the association of a continent ileocecal valve and the degree of severity of the CT signs in patients presenting with large bowel obstruction due to colonic cancer.

Patients And Methods: Sixty-six patients undergoing emergency surgery for confirmed obstructive colonic cancer were included. The CT examinations were analyzed without consultation of the surgical results. Read More

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http://link.springer.com/10.1007/s10140-018-01667-8
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http://dx.doi.org/10.1007/s10140-018-01667-8DOI Listing
January 2019
7 Reads

Epidemiology and Outcomes of Acute Kidney Injury in Critically Ill: Experience from a Tertiary Care Center.

Indian J Nephrol 2018 Nov-Dec;28(6):413-420

Department of Nephrology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

There is only limited information on the epidemiology and outcomes of acute kidney injury (AKI) in critically ill patients from low- and middle-income countries. This study aims to identify the etiology, short-term outcomes, and determinants of mortality in patients with AKI admitted to multiple medical and surgical Intensive Care Units (ICU's) in a tertiary care center. The study also aims to compare the clinical characteristics and outcomes of community-acquired AKI (CAAKI) and hospital-acquired AKI (HAAKI). Read More

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http://dx.doi.org/10.4103/ijn.IJN_191_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309393PMC
January 2019
1 Read

Colonic stenting for malignant large bowel obstruction is safe and effective: a single-surgeon experience.

Singapore Med J 2019 Jan 15. Epub 2019 Jan 15.

Department of Colorectal Surgery, Singapore General Hospital, Singapore.

Introduction: Self-expanding metal stents (SEMS) can be used as a bridge to surgery (BTS) or for palliation in the treatment of malignant large bowel obstruction. This case series evaluates the short-term outcomes of SEMS and success rates over time.

Methods: A total of 75 consecutive patients who underwent colonic stenting for malignant colonic obstruction over a period of six years were included. Read More

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http://dx.doi.org/10.11622/smedj.2019010DOI Listing
January 2019
1 Read

Rectovaginal fistula during treatment with axitinib in a patient with renal cell carcinoma: a case report and review of the literature.

Anticancer Drugs 2019 Jan 11. Epub 2019 Jan 11.

Department of Medical Oncology, ASST-Settelaghi, Circolo Hospital, Varese, Italy.

Renal cell carcinoma (RCC) is one of the most frequent malignancies of the adults. Its incidence has been increasing steadily by 2-4% each year. Up to 30% of patients present with metastases at diagnosis. Read More

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http://dx.doi.org/10.1097/CAD.0000000000000742DOI Listing
January 2019
2 Reads

Risk factors for perforation during endoscopic retrograde cholangiopancreatography in post-reconstruction intestinal tract.

World J Clin Cases 2019 Jan;7(1):10-18

First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.

Background: Endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgically altered anatomy has been a major challenge to gastrointestinal endoscopists with low success rates for reaching the target site as well as high complication rates. The knowledge of ERCP-related risk factors is important for reducing unexpected complications.

Aim: To identify ERCP-related risk factors for perforation in patients with surgically altered anatomy. Read More

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http://dx.doi.org/10.12998/wjcc.v7.i1.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327124PMC
January 2019
1 Read

Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial.

Authors:

Lancet 2019 02 8;393(10170):423-433. Epub 2019 Jan 8.

Background: Infections acquired in hospital are an important cause of morbidity and mortality in very preterm infants. Several small trials have suggested that supplementing the enteral diet of very preterm infants with lactoferrin, an antimicrobial protein processed from cow's milk, prevents infections and associated complications. The aim of this large randomised controlled trial was to collect data to enhance the validity and applicability of the evidence from previous trials to inform practice. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183222
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http://dx.doi.org/10.1016/S0140-6736(18)32221-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356450PMC
February 2019
4 Reads

Spontaneous ileocecal perforation induced by deep endometriosis.

JBRA Assist Reprod 2019 Jan 11. Epub 2019 Jan 11.

Preventative Gynecology Research Center (PGRC), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Bowel endometriosis is a rare condition that may cause catastrophic complications necessitating immediate medical attention. This report describes the case of a patient diagnosed with endometriosis-induced bowel perforation. Albeit rare, bowel perforations caused by endometriosis should be considered in the differential diagnosis of women of reproductive age with abdominal pain. Read More

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http://dx.doi.org/10.5935/1518-0557.20180087DOI Listing
January 2019
1 Read

Rare acute abdominal condition caused by mesenteric fibromatosis perforation: A case report.

Medicine (Baltimore) 2019 Jan;98(2):e14115

Rationale: Mesenteric fibromatosis is a rare benign neoplasm with a tendency to spread and recur locally, without metastasis. It may present with a wide spectrum of clinical features; however, onset as a perforation is extremely rare.

Patient Concerns: The present patient was an 18-year-old female with a 10-hour history of increasing abdominal pain that arose suddenly with nausea and vomiting. Read More

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http://dx.doi.org/10.1097/MD.0000000000014115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336540PMC
January 2019
4 Reads

Pneumatosis Intestinalis and Intestinal Perforation in a Patient Receiving Tocilizumab.

Arch Rheumatol 2018 Sep 17;33(3):372-375. Epub 2018 Jan 17.

Department of Rheumatology, Barts Health NHS Trust, London, United Kingdom.

In this article, we report a case of pneumatosis intestinalis associated with tocilizumab use. This is a unique case and may explain the increased rate of idiopathic bowel perforation among patients taking tocilizumab. Read More

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http://dx.doi.org/10.5606/ArchRheumatol.2018.6668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328221PMC
September 2018

Treatment of Abdominal Surgical Wound Dehiscence With Bowel Exposure and Infection: Using Intrawound Continuous Negative Pressure, Irrigation, and Application of Artificial Dermis.

Ann Plast Surg 2019 Feb;82(2):213-217

From the Department of Plastic & Reconstructive Surgery and Maxillofacial Surgery, Kurume University Hospital, Fukuoka, Japan.

Abdominal surgical wound dehiscence with bowel exposure and infection carries a risk of intestinal fistula, making it extremely difficult to treat. The objective at this time is to heal such wounds safely and absolutely with using intrawound continuous negative pressure and irrigation treatment and artificial dermis. The subjects were 18 patients with abdominal wall dehiscence wounds with bowel exposure. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001739DOI Listing
February 2019
8 Reads

Rare complications of multikinase inhibitor treatment.

Arch Endocrinol Metab 2018 ;62(6):636-640

Division of Endocrinology, University of Buenos Aires, Buenos Aires, Argentina.

Objective: The advent of multikinase inhibitor (MKI) therapy has led to a radical change in the treatment of patients with advanced thyroid carcinoma. The aim of this manuscript is to communicate rare adverse events that occurred in less than 5% of patients in clinical trials in a subset of patients treated in our hospital.

Subjects And Methods: Out of 760 patients with thyroid cancer followed up with in our Division of Endocrinology, 29 (3. Read More

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http://dx.doi.org/10.20945/2359-3997000000090DOI Listing
February 2019
6 Reads

Counteraction of perforated cecum lesions in rats: Effects of pentadecapeptide BPC 157, L-NAME and L-arginine.

World J Gastroenterol 2018 Dec;24(48):5462-5476

Departments of Pharmacology and Pathology, Medical Faculty University of Zagreb, Zagreb 10000, Croatia.

Aim: To study the counteraction of perforated cecum lesion using BPC 157 and nitric oxide (NO) system agents.

Methods: Alongside with the agents' application (after 1 min, medication (/kg, 10 mL/2 min bath/rat) includes: BPC 157 (10 μg), L-NAME (5 mg), L-arginine (100mg) alone or combined, and saline baths (controls)) on the rat perforate cecum injury, we continuously assessed the gross reappearance of the vessels (USB microcamera) quickly propagating toward the defect at the cecum surface, defect contraction, bleeding attenuation, MDA- and NO-levels in cecum tissue at 15 min, and severity of cecum lesions and adhesions at 1 and 7 d.

Results: Post-injury, during/after a saline bath, the number of vessels was significantly reduced, the defect was slightly narrowed, bleeding was significant and MDA-levels increased and NO-levels decreased. Read More

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http://dx.doi.org/10.3748/wjg.v24.i48.5462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319139PMC
December 2018
2 Reads
2.369 Impact Factor

Complications of newborn enterostomies.

World J Clin Cases 2018 Dec;6(16):1101-1110

Department of Pediatric Surgery, University Hospital Frankfurt, Goethe-University Frankfurt am Main, Frankfurt 60590, Germany.

Aim: To evaluate the occurrence and severity of enterostomy complications in newborns suffering from different intestinal disorders.

Methods: A 10-year retrospective cohort study (2008-2017) investigated newborns that underwent enterostomy formation and reversal for different intestinal disorders. Only infants less than 28 d old at the time of enterostomy creation were included in the study (corrected age was applied in the cases of preterm neonates). Read More

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http://dx.doi.org/10.12998/wjcc.v6.i16.1101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306644PMC
December 2018
3 Reads

Risk factors for failure of hydrostatic reduction of intussusception in pediatric patients: A retrospective study.

Medicine (Baltimore) 2019 Jan;98(1):e13826

Department of Pediatric Surgery, West China Hospital, Sichuan University, China.

The aim of this current study was to explore the risk factors associated with failure of hydrostatic reduction of intussusception in pediatric patients.Patients with intussusception treated with hydrostatic reduction from January 2010 to December 2016 were retrospectively analyzed. Candidates for inclusion in the study were children from 0 to 18 who were diagnosed with intussusception and treated with hydrostatic reduction. Read More

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http://dx.doi.org/10.1097/MD.0000000000013826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344150PMC
January 2019
1 Read

[Immediate results of surgical treatment of complicated colorectal cancer in elderly and senile patients.]

Adv Gerontol 2018 ;31(4):574-580

I.I.Mechnikov Northwestern State Medical University, 41, Kirochnaya str., St. Petersburg, 191015, Russian Federation.

The work analyzes the results of surgical treatment of 545 elderly and senile patients with complicated forms of colon cancer. Among colon cancer complications frequently encountered acute intestinal obstruction (AIO) - 413 (75,8%), less likely to have been identified - perifocal inflammation (PPV) with abscess - 80 (14,7%), bleeding - 30 (5,5 %) and tumor perforation - 22 (4%). Operations on the colon were performed as a traditional method - 408 (74,9%) and with the use of endovideosurgical technologies - 137 (25,1%). Read More

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January 2018
1 Read

Hemoperitoneum due to a Perforated Meckel Diverticulum.

Am Surg 2018 Dec;84(12):e561-e563

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December 2018
7 Reads

[Prognostic value of combining preoperative serum tumor markers and peripheral blood routine indexes in patients with colorectal cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Dec;21(12):1421-1426

Department of Gastrointestinal Surgery, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China, Email:

Objective: To investigate the prognostic value of preoperative serum tumor markers combined with peripheral blood routine indexes in colorectal cancer patients.

Methods: From January 2010 to March 2013, clinicopathological data of colorectal cancer patients receiving surgery treatment at the Third Affiliated Hospital of Sun Yat-sen University were collected.

Inclusion Criteria: (1) histologically confirmed adenocarcinoma; (2) primary cancer resected; (3) intact clinical data; (4) no signs of clinical infection. Read More

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December 2018
1 Read

The feasibility of routine use of distal stoma refeeding method in newborns with enterostomy.

J Matern Fetal Neonatal Med 2018 12 25:1-101. Epub 2018 Dec 25.

a Department of Pediatric Surgery , Medical University of Innsbruck , Innsbruck , Austria.

Objective: Temporary enterostomies are life-saving in neonatal surgery, however causing loss of fluid electrolyte, delays in distal bowel adaptation and thus delayed growth of newborns. In this study, we aimed to present the method and clinical results of distal stoma refeeding in premature and mature neonates.

Methods: Between January 2012 and December 2017, records of newborn patients who underwent enterostomy and distal stoma refeeding were retrospectively analysed. Read More

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http://dx.doi.org/10.1080/14767058.2018.1563593DOI Listing
December 2018
2 Reads

Surgical treatment of intestinal perforation in Behçet Syndrome: an unusual presentation.

Pan Afr Med J 2018 26;30:230. Epub 2018 Jul 26.

Hospital de Cascais, Cascais, Portugal.

Behçet syndrome is a chronic, recurring, systemic disorder characterized by the histopathologic finding of nonspecific vasculitis in multiple organs. Behçet syndrome involves the gastrointestinal tract in 10-50% of patients; The main sites of involvement are the terminal ileum and cecum. In patients with Behçet syndrome, CT is advocated for early detection of complications as well as for exclusion of other abdominal pathologic conditions but there is no specific exam. Read More

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http://dx.doi.org/10.11604/pamj.2018.30.230.15950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295296PMC
January 2019
2 Reads