881 results match your criteria Intestinal Leiomyosarcoma


Unplanned reoperation after resection of retroperitoneal sarcoma: experience based on a high-volume sarcoma center.

World J Surg Oncol 2022 May 18;20(1):158. Epub 2022 May 18.

Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.

Background: Most retroperitoneal sarcoma (RPS) operations require combined multi-organ resection, and the proportion of unplanned reoperation is high. However, there are no relevant studies on reoperation for RPS.

Methods: Patients who underwent at least once unplanned reoperation at Shanghai Public Health Clinical Center, Fudan University, China, from August 2009 to December 2021 were retrospectively analyzed. Read More

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Duodenal leiomyosarcoma in a cat: Cytologic, pathologic, and immunohistochemical findings.

Vet Clin Pathol 2022 Apr 24. Epub 2022 Apr 24.

Setor de Patologia Veterinária, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

A 7-year-old mixed-breed neutered male cat was presented with a history of chronic vomiting with increased frequency in the last month, progressing to depression and profuse projectile vomiting. Abdominal ultrasonography revealed an area of marked segmental duodenal thickening associated with a nodule, and euthanasia was performed due to a poor prognosis. Grossly, at the postmortem examination, the wall of a duodenal segment was severely expanded by a nodule measuring 5. Read More

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The double challenge (preoperative diagnosis and surgical approach) of primary leiomyosarcoma of the sigmoid colon.

Acta Biomed 2022 Apr 14;93(S1):e2022124. Epub 2022 Apr 14.

Department of Medicine and Surgery, University of Parma, Parma (PR), Italy..

Background And Aim: Primary colonic leiomyosarcoma (cLMS) is a rare malignancy of muscularis mucosae or muscularis propria showing highly aggressive behaviour and poor prognosis. To date, making a preoperative diagnosis and performing the most appropriate treatment represent laborious tasks for the clinicians. On the one hand, in fact, cLMS diagnosis is often difficult to achieve preoperatively because of the low specificity of clinical, radiological and bioptical features: for these motives, the diagnosis is usually obtained at postoperative histology/immune-histochemistry. Read More

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A case of pulmonary leiomyosarcoma achieving long-term survival after multiple metastasectomies.

Int Cancer Conf J 2022 Apr 14;11(2):129-133. Epub 2022 Feb 14.

Department of Surgery, Yodogawa Christian Hospital, 1-7-50, Kunijima, Higashiyodogawa-ku, Osaka, 533-0024 Japan.

A 58-year-old man who underwent lower lobectomy of the right lung for primary pulmonary leiomyosarcoma (PPL) 4 years ago presented with epigastric pain and was diagnosed with small bowel intussusception caused by an intestinal mass. Partial resection of the small intestine was performed, and pathological examination revealed metastatic leiomyosarcoma. Masses in the left adrenal gland, subcutaneous tissue of the left upper arm, right pleura, jejunum, right trapezius muscle, and right adrenal gland were subsequently detected in the following 4 years. Read More

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Case Report: Giant Multiloculated Pseudocystic Jejunal Leiomyosarcoma in a Dog: Atypical Morphologic Features of Canine Intestinal Leiomyosarcoma.

Front Vet Sci 2022 8;9:791133. Epub 2022 Feb 8.

Department of Veterinary Emergency and Critical Care Medcine, Konkuk Veterinary Medical Teaching Hospital, Konkuk University, Seoul, South Korea.

A 10-year-old intact female Rottweiler dog weighing 29 kg presented with 2 days history of vomiting, anorexia, and lethargy to KonKuk University Teaching Hospital, Seoul, South Korea. Ultrasonography and computed tomography (CT) scannings revealed a well-demarcated, large mass (29 × 19 × 11 cm) with numerous fluid-filled cavities. Metastases to adjacent lymph nodes were also identified on CT. Read More

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February 2022

Leiomyosarcoma of urinary bladder with unusual recurrence in intestinal mucosa and peritoneum: a case report.

J Egypt Natl Canc Inst 2021 Dec 13;33(1):38. Epub 2021 Dec 13.

Department of Cytology and Gynaecological Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Background: Leiomyosarcomas of urinary bladder constitute rare malignant sarcomas with very few cases reported in literature.

Case Presentation: Here, we present a case of bladder leiomyosarcoma in a well-preserved female. She failed to respond to standard chemotherapy and had a rapidly downhill course with unusual metastases in anastomotic site and peritoneum soon after surgery. Read More

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December 2021

Spindle Cell Sarcoma (SCS); a case of primary leiomyosarcoma (LMS) of the sigmoid colon presented as intestinal obstruction.

J Surg Case Rep 2021 Nov 30;2021(11):rjab515. Epub 2021 Nov 30.

Department of Surgery, Al-Mouwasat University Hospital, Mazzah, Damascus, Syria.

Leiomyosarcoma (LMS) is a common form of soft tissue sarcoma. Primary colonic LMS is an extremely rare entity, comprising 1-2% of gastrointestinal malignancies. Primary mesenchymal sarcomas of the gastrointestinal system are rare and constitute just 0. Read More

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November 2021

Giant leiomyosarcoma of the transverse colon.

BMJ Case Rep 2021 Dec 2;14(12). Epub 2021 Dec 2.

General Surgery, Carlsbad Medical Center, Carlsbad, New Mexico, USA.

Leiomyosarcoma (LMS) of the colon accounts for <1% of all colorectal malignancies. Our patient was a 72-year-old man with a history of aortic valvular disorder and congestive heart failure, who presented with an abdominal mass and no constitutional symptoms. The CT scan finding suggested a large tumour with both solid and cystic components. Read More

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December 2021

Bilateral lower extremity induration in a patient with leiomyosarcoma.

Lancet Oncol 2021 10;22(10):e466

Harvard Medical School, Boston, MA, USA; Department of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.

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October 2021

Small intestine leiomyosarcoma mimicking gastrointestinal stromal tumour.

BMJ Case Rep 2021 Sep 13;14(9). Epub 2021 Sep 13.

Department of Surgery, All India Institute of Medical Sciences, New Delhi, India.

Small bowel malignant tumours make only 2% of all gastrointestinal (GI) malignancies. Small bowel leiomyosarcoma (LMS) is further rare, accounts for only 0.1%-3% fraction of these tumours. Read More

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September 2021

[Clinicopathological features of malignant mixed mesodermal tumor: analysis of 50 cases].

Zhonghua Bing Li Xue Za Zhi 2021 Sep;50(9):1008-1013

Department of Pathology, the Seventh Medical Center of PLA General Hospital, Beijing 100700, China.

To investigate the clinicpathological, immunohistochemical and molecular genetic features of malignant mixed mesodermal tumor (MMMT) in the female reproductive system. To analyze its histopathological characteristics, we performed a retrospective review of the MMMT cases diagnosed at PLA General Hospital, Beijing, China during 2005-2019 using its surgical and pathological databases. EnVision immunohistochemical staining was used to detect the expression of ER, PR, p16, p53 and MMR proteins. Read More

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September 2021

Caecal desmoid tumour: a rare tumour at uncommon location and review of literature.

BMJ Case Rep 2021 Jun 4;14(6). Epub 2021 Jun 4.

General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India

A 49-year-old woman presented to surgery outpatient clinic with the awareness of a right lower abdomen asymptomatic lump for one week. Contrast-enhanced CT of the abdomen demonstrated a 10×11×15 cm heterogeneous lesion anterior to the ileocecal junction with the possibility of leiomyosarcoma. The patient was prepared for laparotomy and intraoperative there was a large tumour arising from the medial wall of cecum. Read More

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Ileocolonic intussusception caused by epithelioid leiomyosarcoma of the ileum: a report of case and review of the literature.

Ann Coloproctol 2022 Apr 28;38(2):176-180. Epub 2021 May 28.

Department of General Surgery, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea.

Small intestinal malignant tumor accounts for about 3% of all malignant tumors in the gastrointestinal tract, among which 13% are leiomyosarcoma (LMS). In addition, epithelioid LMS is of very rare occurrence. As small intestinal malignant tumors are initially asymptomatic and nonspecific, diagnosis is often delayed, and this can lead to large tumor at the time of detection and lead to intussusception. Read More

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Right ureteric reconstruction with vascularised interpositional appendix graft in retroperitoneal leiomyosarcoma.

Med J Malaysia 2021 05;76(3):432-435

Sarawak General Hospital, Department of Surgery, Sarawak, Malaysia.

We present here a case of a 66-year-old lady who was diagnosed with right iliac fossa retroperitoneal leiomyosarcoma at Hospital Umum Sarawak. The challenge in this case was the extension of tumour with the involvement of her right ureter causing proximal hydroureter and hydronephrosis. After resection of tumour en-block with the involved segment of ureter, it was not possible to repair the ureteric defect directly. Read More

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A Case of Liver Metastasis from Small Intestinal Gastrointestinal Stromal Tumor 25 Years after Surgery including Autopsy Findings.

Case Rep Gastrointest Med 2021 24;2021:6642427. Epub 2021 Feb 24.

Division of Gastroenterology, Department of Internal Medicine, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japan.

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor in the digestive tract. Recurrences may occur even after radical resection; however, recurrence later than 10 years after surgery is rare. We report a case of GIST with recurrence of liver metastasis 25 years after surgery. Read More

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February 2021

Perforation of intestinal leiomyosarcoma: A case report.

Int J Surg Case Rep 2021 Feb 19;79:327-330. Epub 2021 Jan 19.

Department of Surgery, Tokyo Bay Medical Center, 3-4-32 Todaijima, Urayasu, Chiba, 279-0001, Japan. Electronic address:

Introduction And Importance: The majority of gastrointestinal sarcoma is gastrointestinal stromal tumors and intestinal leiomyosarcoma is rare. Small intestinal mesenchymal tumors are often large at diagnosis, and they commonly present with bleeding or intussusception. We report a perforation associated with intestinal leiomyosarcoma. Read More

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February 2021

Intestinal Myxoid Leiomyosarcoma in a Sambar Deer (Rusa unicolor).

J Comp Pathol 2020 Oct 1;180:69-72. Epub 2020 Oct 1.

California Animal Health and Food Safety Laboratory, School of Veterinary Medicine, University of California Davis, San Bernardino, California, USA.

A 9-year-old male sambar deer (Rusa unicolor) that died during sedation had a large and firm polypoid mass, which expanded the small intestinal wall and partially obstructed the duodenal lumen. Histopathology revealed a pleomorphic sarcoma composed of stellate to spindloid cells loosely arranged in an abundant myxoid matrix. The cytoplasm of the neoplastic cells was strongly immunopositive for vimentin and smooth muscle actin, but negative for c-KIT, desmin and myoglobin. Read More

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October 2020

Very delayed liver metastasis from small bowel gastrointestinal stromal tumor (32 years after resection of the small bowel GIST): Report of a case.

Int J Surg Case Rep 2020 28;76:156-160. Epub 2020 Sep 28.

Department of Radiology, Okayama Rosai Hospital, Okayama, Japan.

Introduction: Recurrent forms of gastrointestinal stromal tumor (GIST) include liver metastases and peritoneal dissemination. Recurrence often occurs within 2 years. We report a case of liver metastasis, which was detected 30 years after resection of a primary lesion in the small intestine and was resected 32 years later. Read More

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September 2020

Leiomyosarcoma of the transverse colon with lymph node metastasis and malignant transformation: a case report.

Surg Case Rep 2020 Oct 2;6(1):256. Epub 2020 Oct 2.

Department of Gastrointestinal Surgery, Tokyo Medical University Ibaraki Medical Center, 3-20-1 Chuo, AmimachiIbaraki, Inashiki-gun, 300-0395, Japan.

Background: The concept of GIST was established in 1998, clearly differentiating between gastrointestinal leiomyosarcoma and GISTs among gastrointestinal mesenchymal tumors. Lymph node metastasis is extremely rare in true gastrointestinal leiomyosarcoma, and there are no reports of malignant transformation from leiomyoma.

Case Presentation: The patient was an old woman who had undergone endoscopic mucosal resection for an Is polyp on the left side of the transverse colon at the age of 73. Read More

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October 2020

Leiomyosarcoma of the small intestine presenting as abdominal myofascial pain syndrome (AMPS): case report.

Scand J Pain 2021 01 25;21(1):191-193. Epub 2020 Sep 25.

University Hospitals of Leicester NHS Trust, Gwendolen Road, Leicester, UK.

Objective: To highlight an extremely unusual presentation of an aggressive, rare small bowel malignancy presenting as abdominal myofascial pain syndrome.

Case Presentation: The report is presented from a tertiary pain medicine unit at a university teaching hospital. A female patient presenting with chronic abdominal pain was initially diagnosed as abdominal myofascial pain syndrome. Read More

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January 2021

Recurrent Leiomyosarcoma of the Small Bowel: A Case Series.

Anticancer Res 2020 Jul;40(7):4199-4204

Department of General Surgery, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, University of Genoa, Genoa, Italy.

Background/aim: Leiomyosarcoma is an extremely rare, small bowel neoplasm (2% of all gastrointestinal tumours). Early diagnosis is challenging due to the slow growth of the cancer. The biological behaviour of this group of tumours is aggressive, and the first-line treatment is surgical resection. Read More

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Ileo-ileal intussusception caused by small bowel leiomyosarcoma: A rare case report.

Int J Surg Case Rep 2020 29;72:52-55. Epub 2020 May 29.

Colorectal Surgery Unit, Università Campus Bio-Medico, Rome, Italy.

Introduction: Intussusception is the telescoping of one segment of the bowel into an adjacent bowel segment, causing venous congestion, edema, and blood supply reduction. We present a case of ileo-ileal intussusception in an adult patient with intestinal obstruction caused by a rare mesenchymal malignant lesion of the distal ileum: Leiomyosarcoma (LMS).

Presentation Of Case: A 90-year-old Caucasian man presented to the hospital with a two-day history of abdominal pain, nausea, and bowel occlusion. Read More

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Palliative treatment with electrochemotherapy in recurrent or metastatic vaginal cancer.

Int J Gynecol Cancer 2020 07 30;30(7):939-946. Epub 2020 May 30.

Gynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, Bologna, Italy.

Objective: Vaginal metastases are very rare events with a poor prognosis. To improve the quality of life, local treatments should be considered. The aim of this study was to evaluate the role of electrochemotherapy as palliative treatment in vaginal cancer not amenable to standard treatments due to poor performance status, previous treatments, or advanced disease. Read More

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A pooled analysis of risk factors of surgically treated leiomyosarcoma of the colon in adults.

World J Surg Oncol 2020 Mar 28;18(1):61. Epub 2020 Mar 28.

Department of Digestive System, Qinghai University Affiliated Hospital, Xining, 810000, Qinghai, China.

Background: This current systematic review aimed to evaluate the role of surgical management and risk factors by pooled cases from all identified patients with colonic leiomyosarcomas.

Methods: The authors searched the Ovid MEDLINE, Embase, PubMed, and Cochrane databases using the keywords "colonic," "colon," and "leiomyosarcoma." Risk factors of colonic leiomyosarcoma in the pooled cohort were also evaluated. Read More

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Outcomes of palliative-intent surgery in retroperitoneal sarcoma-Results from the US Sarcoma Collaborative.

J Surg Oncol 2020 Jun 13;121(7):1140-1147. Epub 2020 Mar 13.

Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.

Background And Objectives: Outcomes of palliative-intent surgery in retroperitoneal sarcomas (RPS) are not well understood. This study aims to define indications for and outcomes after palliative-intent RPS resection.

Methods: Using a retrospective 8-institution database, patients undergoing resection of primary/recurrent RPS with palliative intent were identified. Read More

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Incidence and time trends of sarcoma (2000-2013): results from the French network of cancer registries (FRANCIM).

BMC Cancer 2020 Mar 6;20(1):190. Epub 2020 Mar 6.

French Network of Cancer Registries, F-31000, Toulouse, France.

Background: The exhaustive collection of new sarcoma cases and their second histologic review offer a unique opportunity to study their incidence and time trends in France according to the major subtypes.

Methods: Data were collected from population-based cancer registries covering 22% of the French population. Crude and world age-standardized incidence rates (ASR) were estimated according to anatomic, histological and genetic groups, age and sex over the 2010-2013 period. Read More

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Long-Term Survival After Multidisciplinary Treatment Including Surgery for Metachronous Metastases of Small Intestinal Gastrointestinal Stromal Tumors after Curative Resection: A Case Report.

Am J Case Rep 2019 Dec 26;20:1942-1948. Epub 2019 Dec 26.

Department of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.

BACKGROUND Currently, 3 molecular targeted drugs are available for the treatment of unresectable and recurrent gastrointestinal stromal tumors (GISTs), and result in improved prognoses and rare occurrence of bone metastases. However, there is no established treatment guideline for bone metastases of GIST. CASE REPORT The patient was a 56-year-old male who was diagnosed with leiomyosarcoma in 1997. Read More

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December 2019

Leiomyosarcoma of the colon. A very uncommon condition with poor prognosis.

Gastroenterol Hepatol 2020 Apr 18;43(4):200-201. Epub 2019 Dec 18.

Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Arnau de Vilanova, Lleida, España.

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Leiomyosarcoma of the superior mesenteric artery: .

J Surg Case Rep 2019 Nov 6;2019(11):rjz308. Epub 2019 Nov 6.

Oncological and General Surgery Unit, 'St. Giuseppe Moscati' Hospital of National Relevance and High Specialty, Avellino, Italy.

Arterial leiomyosarcoma (A-LMS) is a very rare tumour and no cases originating from the superior mesenteric artery (SMA) have been described. We present a case of A-LMS originating from distal part of SMA and incorporating superior mesenteric vein (SMV). SMA and SMV were prepared along their course by laparotomy. Read More

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November 2019