865 results match your criteria Intestinal Leiomyosarcoma


A Case of Liver Metastasis from Small Intestinal Gastrointestinal Stromal Tumor 25 Years after Surgery including Autopsy Findings.

Case Rep Gastrointest Med 2021 24;2021:6642427. Epub 2021 Feb 24.

Division of Gastroenterology, Department of Internal Medicine, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japan.

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor in the digestive tract. Recurrences may occur even after radical resection; however, recurrence later than 10 years after surgery is rare. We report a case of GIST with recurrence of liver metastasis 25 years after surgery. Read More

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February 2021

Perforation of intestinal leiomyosarcoma: A case report.

Int J Surg Case Rep 2021 Feb 19;79:327-330. Epub 2021 Jan 19.

Department of Surgery, Tokyo Bay Medical Center, 3-4-32 Todaijima, Urayasu, Chiba, 279-0001, Japan. Electronic address:

Introduction And Importance: The majority of gastrointestinal sarcoma is gastrointestinal stromal tumors and intestinal leiomyosarcoma is rare. Small intestinal mesenchymal tumors are often large at diagnosis, and they commonly present with bleeding or intussusception. We report a perforation associated with intestinal leiomyosarcoma. Read More

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February 2021

Intestinal Myxoid Leiomyosarcoma in a Sambar Deer (Rusa unicolor).

J Comp Pathol 2020 Oct 1;180:69-72. Epub 2020 Oct 1.

California Animal Health and Food Safety Laboratory, School of Veterinary Medicine, University of California Davis, San Bernardino, California, USA.

A 9-year-old male sambar deer (Rusa unicolor) that died during sedation had a large and firm polypoid mass, which expanded the small intestinal wall and partially obstructed the duodenal lumen. Histopathology revealed a pleomorphic sarcoma composed of stellate to spindloid cells loosely arranged in an abundant myxoid matrix. The cytoplasm of the neoplastic cells was strongly immunopositive for vimentin and smooth muscle actin, but negative for c-KIT, desmin and myoglobin. Read More

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October 2020

Very delayed liver metastasis from small bowel gastrointestinal stromal tumor (32 years after resection of the small bowel GIST): Report of a case.

Int J Surg Case Rep 2020 28;76:156-160. Epub 2020 Sep 28.

Department of Radiology, Okayama Rosai Hospital, Okayama, Japan.

Introduction: Recurrent forms of gastrointestinal stromal tumor (GIST) include liver metastases and peritoneal dissemination. Recurrence often occurs within 2 years. We report a case of liver metastasis, which was detected 30 years after resection of a primary lesion in the small intestine and was resected 32 years later. Read More

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September 2020

Leiomyosarcoma of the transverse colon with lymph node metastasis and malignant transformation: a case report.

Surg Case Rep 2020 Oct 2;6(1):256. Epub 2020 Oct 2.

Department of Gastrointestinal Surgery, Tokyo Medical University Ibaraki Medical Center, 3-20-1 Chuo, AmimachiIbaraki, Inashiki-gun, 300-0395, Japan.

Background: The concept of GIST was established in 1998, clearly differentiating between gastrointestinal leiomyosarcoma and GISTs among gastrointestinal mesenchymal tumors. Lymph node metastasis is extremely rare in true gastrointestinal leiomyosarcoma, and there are no reports of malignant transformation from leiomyoma.

Case Presentation: The patient was an old woman who had undergone endoscopic mucosal resection for an Is polyp on the left side of the transverse colon at the age of 73. Read More

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October 2020

Recurrent Leiomyosarcoma of the Small Bowel: A Case Series.

Anticancer Res 2020 Jul;40(7):4199-4204

Department of General Surgery, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, University of Genoa, Genoa, Italy.

Background/aim: Leiomyosarcoma is an extremely rare, small bowel neoplasm (2% of all gastrointestinal tumours). Early diagnosis is challenging due to the slow growth of the cancer. The biological behaviour of this group of tumours is aggressive, and the first-line treatment is surgical resection. Read More

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Ileo-ileal intussusception caused by small bowel leiomyosarcoma: A rare case report.

Int J Surg Case Rep 2020 29;72:52-55. Epub 2020 May 29.

Colorectal Surgery Unit, Università Campus Bio-Medico, Rome, Italy.

Introduction: Intussusception is the telescoping of one segment of the bowel into an adjacent bowel segment, causing venous congestion, edema, and blood supply reduction. We present a case of ileo-ileal intussusception in an adult patient with intestinal obstruction caused by a rare mesenchymal malignant lesion of the distal ileum: Leiomyosarcoma (LMS).

Presentation Of Case: A 90-year-old Caucasian man presented to the hospital with a two-day history of abdominal pain, nausea, and bowel occlusion. Read More

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Palliative treatment with electrochemotherapy in recurrent or metastatic vaginal cancer.

Int J Gynecol Cancer 2020 07 30;30(7):939-946. Epub 2020 May 30.

Gynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, Bologna, Italy.

Objective: Vaginal metastases are very rare events with a poor prognosis. To improve the quality of life, local treatments should be considered. The aim of this study was to evaluate the role of electrochemotherapy as palliative treatment in vaginal cancer not amenable to standard treatments due to poor performance status, previous treatments, or advanced disease. Read More

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A pooled analysis of risk factors of surgically treated leiomyosarcoma of the colon in adults.

World J Surg Oncol 2020 Mar 28;18(1):61. Epub 2020 Mar 28.

Department of Digestive System, Qinghai University Affiliated Hospital, Xining, 810000, Qinghai, China.

Background: This current systematic review aimed to evaluate the role of surgical management and risk factors by pooled cases from all identified patients with colonic leiomyosarcomas.

Methods: The authors searched the Ovid MEDLINE, Embase, PubMed, and Cochrane databases using the keywords "colonic," "colon," and "leiomyosarcoma." Risk factors of colonic leiomyosarcoma in the pooled cohort were also evaluated. Read More

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Outcomes of palliative-intent surgery in retroperitoneal sarcoma-Results from the US Sarcoma Collaborative.

J Surg Oncol 2020 Jun 13;121(7):1140-1147. Epub 2020 Mar 13.

Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.

Background And Objectives: Outcomes of palliative-intent surgery in retroperitoneal sarcomas (RPS) are not well understood. This study aims to define indications for and outcomes after palliative-intent RPS resection.

Methods: Using a retrospective 8-institution database, patients undergoing resection of primary/recurrent RPS with palliative intent were identified. Read More

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Incidence and time trends of sarcoma (2000-2013): results from the French network of cancer registries (FRANCIM).

BMC Cancer 2020 Mar 6;20(1):190. Epub 2020 Mar 6.

French Network of Cancer Registries, F-31000, Toulouse, France.

Background: The exhaustive collection of new sarcoma cases and their second histologic review offer a unique opportunity to study their incidence and time trends in France according to the major subtypes.

Methods: Data were collected from population-based cancer registries covering 22% of the French population. Crude and world age-standardized incidence rates (ASR) were estimated according to anatomic, histological and genetic groups, age and sex over the 2010-2013 period. Read More

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Long-Term Survival After Multidisciplinary Treatment Including Surgery for Metachronous Metastases of Small Intestinal Gastrointestinal Stromal Tumors after Curative Resection: A Case Report.

Am J Case Rep 2019 Dec 26;20:1942-1948. Epub 2019 Dec 26.

Department of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.

BACKGROUND Currently, 3 molecular targeted drugs are available for the treatment of unresectable and recurrent gastrointestinal stromal tumors (GISTs), and result in improved prognoses and rare occurrence of bone metastases. However, there is no established treatment guideline for bone metastases of GIST. CASE REPORT The patient was a 56-year-old male who was diagnosed with leiomyosarcoma in 1997. Read More

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December 2019

Leiomyosarcoma of the colon. A very uncommon condition with poor prognosis.

Gastroenterol Hepatol 2020 Apr 18;43(4):200-201. Epub 2019 Dec 18.

Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Arnau de Vilanova, Lleida, España.

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Leiomyosarcoma of the superior mesenteric artery: .

J Surg Case Rep 2019 Nov 6;2019(11):rjz308. Epub 2019 Nov 6.

Oncological and General Surgery Unit, 'St. Giuseppe Moscati' Hospital of National Relevance and High Specialty, Avellino, Italy.

Arterial leiomyosarcoma (A-LMS) is a very rare tumour and no cases originating from the superior mesenteric artery (SMA) have been described. We present a case of A-LMS originating from distal part of SMA and incorporating superior mesenteric vein (SMV). SMA and SMV were prepared along their course by laparotomy. Read More

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November 2019

Tumour-bowel fistula as a possible complication of pazopanib therapy in retroperitoneal leiomyosarcoma.

BMJ Case Rep 2019 Nov 10;12(11). Epub 2019 Nov 10.

Critical Care Medicine, Mayo Clinic, Jacksonville, Florida, USA.

Pazopanib is a vascular endothelial growth factor receptor tyrosine kinase inhibitor (VEGFR TKI) that inhibits the vascular endothelial growth factor receptor A pathway and has the potential to cause ischaemic bowel changes, including perforation. Here we report a case of a 51-year-old man with large, metastatic, retroperitoneal leiomyosarcoma that developed a tumour-bowel fistula after 4 weeks of pazopanib therapy. He presented to the emergency department with sepsis and 1-week history of worsening fever, chills, nausea and diarrhoea. Read More

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November 2019

Palliative treatment of intestinal obstruction in patients with gynecologic malignancies - single center experience.

Ginekol Pol 2019 ;90(9):496-499

2nd Chair and Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Objectives: One of the common symptoms in patients with advanced gynecologic tumors is intestinal obstruction. Palliativemanagement may include pharmacological treatment, stenting as well as surgical removal of obstruction cause.Selection of appropriate treatment should be based on careful and individual assessment of advantages, disadvantagesand possible complications. Read More

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A very rare cause of the intra-abdominal bleeding.

Turk J Gastroenterol 2019 Sep;30(9):846-847

Department of General Surgery, Yeni Yüzyıl University Gaziosmanpaşa Hospital, İstanbul, Turkey.

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September 2019

Complete Remission of Associative Immune-Mediated Hemolytic Anemia in a Dog Following Surgical Resection of Intestinal Leiomyosarcoma.

Vet Sci 2019 Jun 13;6(2). Epub 2019 Jun 13.

Yuki Animal Hospital, 2-99 Kiba-cho, Minato-ku, Aichi 4550021, Japan.

A twelve-year-old male castrated Chihuahua with a severe, microcytic, hypochromic, and nonregenerative direct antiglobulin test positive anemia characterized by marked spherocytosis was referred to the veterinary hospital. Abdominal ultrasound revealed a peritoneal mass of unclear origin. Transfusion, followed by mass resection, rapidly resolved the anemia without further immunosuppressive treatment. Read More

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Incidence of soft tissue sarcoma in Taiwan: A nationwide population-based study (2007-2013).

Cancer Epidemiol 2019 06 2;60:185-192. Epub 2019 May 2.

Therapeutical and Research Center of Musculoskeletal Tumor, Department of Orthopedics, Taipei Veterans General Hospital, Taipei, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Division of Medical Oncology, Center for Immuno-oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address:

Background: Asian studies on soft tissue sarcoma (STS) incidence, irrespective of the primary site, are scant.

Methods: STS data were acquired from the population-based 2007-2013 Taiwan Cancer Registry of the Health and Welfare Data Science Center, Taiwan. Histological subtype-, site-, sex-, and age-specific STS incidence rates were analyzed according to the 2013 classification of the World Health Organization. Read More

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Large primary leiomyosarcoma of the seminal vesicle: A case report and literature revision.

Arch Ital Urol Androl 2019 Mar 29;91(1):55-57. Epub 2019 Mar 29.

Department of Urology, M.G. Vannini Hospital, Rome.

Primary Leiomyosarcoma of the seminal vesicle is a very rare condition. We report a case of a 74-year-old man with a tumour detected by rectal symptoms with pelvic pain and dysuria at ultrasonography. Computed tomography and magnetic resonance imaging suggest an origin in the left seminal vesicle and did not show a clear cleavage plan with the rectum and a right hydroureteronephrosis was also present. Read More

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Ileal leiomyosarcoma presenting with intussusception.

J Surg Case Rep 2019 Feb 19;2019(2):rjz052. Epub 2019 Feb 19.

Department of Abdominal Surgery, University Medical Centre Ljubljana, Zaloška 7, SI-1525 Ljubljana, Slovenia.

Intussusception is a rare cause of small bowel obstruction in adults, up to 30% of cases are caused by small bowel malignancy. Intestinal leiomyosarcoma is an extremely rare malignant mesenchymal tumour. An 80-year-old male presented with small bowel obstruction. Read More

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February 2019

Leiomyosarcoma Manifesting With Bowel Obstruction.

J Obstet Gynaecol Can 2020 02 14;42(2):109. Epub 2019 Feb 14.

Department of Obstetrics, Gynecology and Newborn Care, The Ottawa Hospital, Ottawa, ON.

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February 2020

Jejunal leiomyosarcoma: Report of a rare case diagnosed on cytology.

Diagn Cytopathol 2019 May 21;47(5):498-502. Epub 2018 Dec 21.

Department of Radiodiagnosis and Interventional Radiology, AIIMS, Jodhpur, India.

Jejunal leiomyosarcomas (LMS) are extremely rare. Of all the mesenchymal tumors of the small intestine, Gastrointestinal Stromal Tumors (GIST) comprise the majority. LMS of the small intestine have been documented as isolated reports or only a very small percentage of the smooth muscle tumors of the small intestine. Read More

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A case of gastric leiomyosarcoma in a domestic shorthair cat.

JFMS Open Rep 2018 Jul-Dec;4(2):2055116918818912. Epub 2018 Dec 6.

Department of Internal Medicine, Highcroft Veterinary Referrals, Bristol, UK.

Case Summary: A 10-year-old male neutered domestic shorthair cat presented with nausea and 1.2 kg weight loss over a 6 month period. Physical examination was unremarkable, and haematological and biochemical results were considered clinically unremarkable. Read More

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December 2018

Resection of a Perirectal Leiomyosarcoma via a Posterior Transcoccygeal Approach.

Ann Surg Oncol 2018 Sep 6;25(9):2641. Epub 2018 Jul 6.

Department of Surgical Oncology, MD Anderson Cancer Center, Houston, TX, USA.

Introduction: The management of perirectal tumors often requires rectal wall resection, and sometimes a complete proctectomy is required. Access to posterior perirectal masses via a posterior, transcoccygeal approach (Kraske procedure) avoids dissection of the intraperitoneal rectum.

Patient: The patient was a 63-year-old male who presented to his primary care physician with debilitating perirectal pain of several months' duration. Read More

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September 2018

Effect of Double-Balloon Enteroscopy on Diagnosis and Treatment of Small-Bowel Diseases.

Chin Med J (Engl) 2018 Jun;131(11):1321-1326

Department of Gastroenterology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong 264000, China.

Background: The diagnosis and treatment of small-bowel diseases is clinically difficult. The purpose of this study was to evaluate the diagnostic and therapeutic value of double-balloon enteroscopy in small-bowel diseases.

Methods: The history and outcomes of 2806 patients who underwent double-balloon enteroscopy from July 2004 to April 2017 were reviewed, which included 562 patients with obscure digestive tract bleeding, 457 patients with obscure diarrhea, 930 patients with obscure abdominal pain, 795 patients with obscure weight loss, and 62 patients with obscure intestinal obstruction. Read More

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Endometrial Stromal Sarcoma With Hyalinizing Giant Rosettes, Mimicking Low-Grade Fibromyxoid Sarcoma.

Int J Surg Pathol 2018 Sep 6;26(6):525-527. Epub 2018 Apr 6.

1 Royal Marsden Hospital, London, UK.

We highlight a rare variant pattern of low-grade endometrial stromal sarcoma showing extensive collagenous rosette formation, closely mimicking low-grade fibromyxoid sarcoma. Additionally, this neoplasm showed diffuse and strong expression of muscle markers, favoring an initial diagnosis of leiomyosarcoma. Reverse transcription-polymerase chain reaction showed the presence of JAZF1-SUZ12 fusion transcripts, and this highlights the broad morphologic and immunophenotypic spectrum of endometrial stromal sarcoma. Read More

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September 2018

Radiation-induced leiomyosarcoma of the rectum after cervical cancer treatment.

Rev Gastroenterol Mex 2018 Oct - Dec;83(4):465-467. Epub 2018 Feb 10.

Departamento de Piel y Partes Blandas, Instituto Nacional de Cancerología, Ciudad de México, México.

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[A Case of Leiomyosarcoma of the Small Intestine with Intestinal Hemorrhage Due to Intraluminal Penetration].

Gan To Kagaku Ryoho 2017 Nov;44(12):1068-1070

Dept. of Surgery, Tohoku University Graduate School of Medicine.

A 40-year-old man was referred to our hospital because of severe anemia and small intestinal tumor revealed by computed tomography. The enteroscopy exam showed the intraluminal penetration of the tumor, which was considered as a cause of anemia. Although emergency operation was performed laparoscopically, intraoperative findings indicated tumor invasion into peritoneum, and we converted from laparoscopic surgery to open surgery that included concomitant peritoneum resection. Read More

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November 2017

Spontaneous rupture of uterine smooth muscle tumour presenting acute abdominal pain and haemoperitoneum.

BMJ Case Rep 2018 Jan 3;2018. Epub 2018 Jan 3.

Chiba Aiyukai Memorial Hospital, Chiba, Japan.

Uterine smooth muscle tumours are histologically categorised into benign leiomyoma, malignant leiomyosarcoma or smooth muscle tumours of uncertain malignant potentials (STUMPs). Common symptoms of uterine tumours are hypermenorrhea, dysmenorrhea, lumbago or irregular genital bleeding. We experienced a case of uterine tumour with atypical clinical behaviour. Read More

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January 2018