855 results match your criteria Intestinal Leiomyosarcoma


Palliative treatment with electrochemotherapy in recurrent or metastatic vaginal cancer.

Int J Gynecol Cancer 2020 May 30. Epub 2020 May 30.

Gynecologic Oncology Unit, Azienda Ospedaliero-Universitaria Policlinico di Sant'Orsola, Bologna, Italy.

Objective: Vaginal metastases are very rare events with a poor prognosis. To improve the quality of life, local treatments should be considered. The aim of this study was to evaluate the role of electrochemotherapy as palliative treatment in vaginal cancer not amenable to standard treatments due to poor performance status, previous treatments, or advanced disease. Read More

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http://dx.doi.org/10.1136/ijgc-2020-001471DOI Listing

Outcomes of palliative-intent surgery in retroperitoneal sarcoma-Results from the US Sarcoma Collaborative.

J Surg Oncol 2020 Jun 13;121(7):1140-1147. Epub 2020 Mar 13.

Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.

Background And Objectives: Outcomes of palliative-intent surgery in retroperitoneal sarcomas (RPS) are not well understood. This study aims to define indications for and outcomes after palliative-intent RPS resection.

Methods: Using a retrospective 8-institution database, patients undergoing resection of primary/recurrent RPS with palliative intent were identified. Read More

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http://dx.doi.org/10.1002/jso.25890DOI Listing
June 2020
3.244 Impact Factor

Incidence and time trends of sarcoma (2000-2013): results from the French network of cancer registries (FRANCIM).

BMC Cancer 2020 Mar 6;20(1):190. Epub 2020 Mar 6.

French Network of Cancer Registries, F-31000, Toulouse, France.

Background: The exhaustive collection of new sarcoma cases and their second histologic review offer a unique opportunity to study their incidence and time trends in France according to the major subtypes.

Methods: Data were collected from population-based cancer registries covering 22% of the French population. Crude and world age-standardized incidence rates (ASR) were estimated according to anatomic, histological and genetic groups, age and sex over the 2010-2013 period. Read More

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http://dx.doi.org/10.1186/s12885-020-6683-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059296PMC

Long-Term Survival After Multidisciplinary Treatment Including Surgery for Metachronous Metastases of Small Intestinal Gastrointestinal Stromal Tumors after Curative Resection: A Case Report.

Am J Case Rep 2019 Dec 26;20:1942-1948. Epub 2019 Dec 26.

Department of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.

BACKGROUND Currently, 3 molecular targeted drugs are available for the treatment of unresectable and recurrent gastrointestinal stromal tumors (GISTs), and result in improved prognoses and rare occurrence of bone metastases. However, there is no established treatment guideline for bone metastases of GIST. CASE REPORT The patient was a 56-year-old male who was diagnosed with leiomyosarcoma in 1997. Read More

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http://dx.doi.org/10.12659/AJCR.918606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944036PMC
December 2019

Leiomyosarcoma of the superior mesenteric artery: .

J Surg Case Rep 2019 Nov 6;2019(11):rjz308. Epub 2019 Nov 6.

Oncological and General Surgery Unit, 'St. Giuseppe Moscati' Hospital of National Relevance and High Specialty, Avellino, Italy.

Arterial leiomyosarcoma (A-LMS) is a very rare tumour and no cases originating from the superior mesenteric artery (SMA) have been described. We present a case of A-LMS originating from distal part of SMA and incorporating superior mesenteric vein (SMV). SMA and SMV were prepared along their course by laparotomy. Read More

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http://dx.doi.org/10.1093/jscr/rjz308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831951PMC
November 2019

Tumour-bowel fistula as a possible complication of pazopanib therapy in retroperitoneal leiomyosarcoma.

BMJ Case Rep 2019 Nov 10;12(11). Epub 2019 Nov 10.

Critical Care Medicine, Mayo Clinic, Jacksonville, Florida, USA.

Pazopanib is a vascular endothelial growth factor receptor tyrosine kinase inhibitor (VEGFR TKI) that inhibits the vascular endothelial growth factor receptor A pathway and has the potential to cause ischaemic bowel changes, including perforation. Here we report a case of a 51-year-old man with large, metastatic, retroperitoneal leiomyosarcoma that developed a tumour-bowel fistula after 4 weeks of pazopanib therapy. He presented to the emergency department with sepsis and 1-week history of worsening fever, chills, nausea and diarrhoea. Read More

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http://dx.doi.org/10.1136/bcr-2019-230727DOI Listing
November 2019

Palliative treatment of intestinal obstruction in patients with gynecologic malignancies - single center experience.

Ginekol Pol 2019 ;90(9):496-499

2nd Chair and Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Objectives: One of the common symptoms in patients with advanced gynecologic tumors is intestinal obstruction. Palliativemanagement may include pharmacological treatment, stenting as well as surgical removal of obstruction cause.Selection of appropriate treatment should be based on careful and individual assessment of advantages, disadvantagesand possible complications. Read More

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http://dx.doi.org/10.5603/GP.2019.0086DOI Listing
May 2020
1 Read

A very rare cause of the intra-abdominal bleeding.

Turk J Gastroenterol 2019 Sep;30(9):846-847

Department of General Surgery, Yeni Yüzyıl University Gaziosmanpaşa Hospital, İstanbul, Turkey.

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http://dx.doi.org/10.5152/tjg.2018.18490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750821PMC
September 2019

Complete Remission of Associative Immune-Mediated Hemolytic Anemia in a Dog Following Surgical Resection of Intestinal Leiomyosarcoma.

Vet Sci 2019 Jun 13;6(2). Epub 2019 Jun 13.

Yuki Animal Hospital, 2-99 Kiba-cho, Minato-ku, Aichi 4550021, Japan.

A twelve-year-old male castrated Chihuahua with a severe, microcytic, hypochromic, and nonregenerative direct antiglobulin test positive anemia characterized by marked spherocytosis was referred to the veterinary hospital. Abdominal ultrasound revealed a peritoneal mass of unclear origin. Transfusion, followed by mass resection, rapidly resolved the anemia without further immunosuppressive treatment. Read More

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http://dx.doi.org/10.3390/vetsci6020055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631155PMC
June 2019
10 Reads

Incidence of soft tissue sarcoma in Taiwan: A nationwide population-based study (2007-2013).

Cancer Epidemiol 2019 06 2;60:185-192. Epub 2019 May 2.

Therapeutical and Research Center of Musculoskeletal Tumor, Department of Orthopedics, Taipei Veterans General Hospital, Taipei, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Division of Medical Oncology, Center for Immuno-oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address:

Background: Asian studies on soft tissue sarcoma (STS) incidence, irrespective of the primary site, are scant.

Methods: STS data were acquired from the population-based 2007-2013 Taiwan Cancer Registry of the Health and Welfare Data Science Center, Taiwan. Histological subtype-, site-, sex-, and age-specific STS incidence rates were analyzed according to the 2013 classification of the World Health Organization. Read More

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http://dx.doi.org/10.1016/j.canep.2019.04.007DOI Listing
June 2019
10 Reads

Large primary leiomyosarcoma of the seminal vesicle: A case report and literature revision.

Arch Ital Urol Androl 2019 Mar 29;91(1):55-57. Epub 2019 Mar 29.

Department of Urology, M.G. Vannini Hospital, Rome.

Primary Leiomyosarcoma of the seminal vesicle is a very rare condition. We report a case of a 74-year-old man with a tumour detected by rectal symptoms with pelvic pain and dysuria at ultrasonography. Computed tomography and magnetic resonance imaging suggest an origin in the left seminal vesicle and did not show a clear cleavage plan with the rectum and a right hydroureteronephrosis was also present. Read More

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http://dx.doi.org/10.4081/aiua.2019.1.55DOI Listing
March 2019
9 Reads

Ileal leiomyosarcoma presenting with intussusception.

J Surg Case Rep 2019 Feb 19;2019(2):rjz052. Epub 2019 Feb 19.

Department of Abdominal Surgery, University Medical Centre Ljubljana, Zaloška 7, SI-1525 Ljubljana, Slovenia.

Intussusception is a rare cause of small bowel obstruction in adults, up to 30% of cases are caused by small bowel malignancy. Intestinal leiomyosarcoma is an extremely rare malignant mesenchymal tumour. An 80-year-old male presented with small bowel obstruction. Read More

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http://dx.doi.org/10.1093/jscr/rjz052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380073PMC
February 2019
8 Reads

Jejunal leiomyosarcoma: Report of a rare case diagnosed on cytology.

Diagn Cytopathol 2019 May 21;47(5):498-502. Epub 2018 Dec 21.

Department of Radiodiagnosis and Interventional Radiology, AIIMS, Jodhpur, India.

Jejunal leiomyosarcomas (LMS) are extremely rare. Of all the mesenchymal tumors of the small intestine, Gastrointestinal Stromal Tumors (GIST) comprise the majority. LMS of the small intestine have been documented as isolated reports or only a very small percentage of the smooth muscle tumors of the small intestine. Read More

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http://doi.wiley.com/10.1002/dc.24136
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http://dx.doi.org/10.1002/dc.24136DOI Listing
May 2019
22 Reads

A case of gastric leiomyosarcoma in a domestic shorthair cat.

JFMS Open Rep 2018 Jul-Dec;4(2):2055116918818912. Epub 2018 Dec 6.

Department of Internal Medicine, Highcroft Veterinary Referrals, Bristol, UK.

Case Summary: A 10-year-old male neutered domestic shorthair cat presented with nausea and 1.2 kg weight loss over a 6 month period. Physical examination was unremarkable, and haematological and biochemical results were considered clinically unremarkable. Read More

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http://dx.doi.org/10.1177/2055116918818912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293366PMC
December 2018
18 Reads

Resection of a Perirectal Leiomyosarcoma via a Posterior Transcoccygeal Approach.

Ann Surg Oncol 2018 Sep 6;25(9):2641. Epub 2018 Jul 6.

Department of Surgical Oncology, MD Anderson Cancer Center, Houston, TX, USA.

Introduction: The management of perirectal tumors often requires rectal wall resection, and sometimes a complete proctectomy is required. Access to posterior perirectal masses via a posterior, transcoccygeal approach (Kraske procedure) avoids dissection of the intraperitoneal rectum.

Patient: The patient was a 63-year-old male who presented to his primary care physician with debilitating perirectal pain of several months' duration. Read More

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http://dx.doi.org/10.1245/s10434-018-6636-xDOI Listing
September 2018
44 Reads

Effect of Double-Balloon Enteroscopy on Diagnosis and Treatment of Small-Bowel Diseases.

Chin Med J (Engl) 2018 Jun;131(11):1321-1326

Department of Gastroenterology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong 264000, China.

Background: The diagnosis and treatment of small-bowel diseases is clinically difficult. The purpose of this study was to evaluate the diagnostic and therapeutic value of double-balloon enteroscopy in small-bowel diseases.

Methods: The history and outcomes of 2806 patients who underwent double-balloon enteroscopy from July 2004 to April 2017 were reviewed, which included 562 patients with obscure digestive tract bleeding, 457 patients with obscure diarrhea, 930 patients with obscure abdominal pain, 795 patients with obscure weight loss, and 62 patients with obscure intestinal obstruction. Read More

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http://dx.doi.org/10.4103/0366-6999.232802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987504PMC
June 2018
15 Reads

Endometrial Stromal Sarcoma With Hyalinizing Giant Rosettes, Mimicking Low-Grade Fibromyxoid Sarcoma.

Int J Surg Pathol 2018 Sep 6;26(6):525-527. Epub 2018 Apr 6.

1 Royal Marsden Hospital, London, UK.

We highlight a rare variant pattern of low-grade endometrial stromal sarcoma showing extensive collagenous rosette formation, closely mimicking low-grade fibromyxoid sarcoma. Additionally, this neoplasm showed diffuse and strong expression of muscle markers, favoring an initial diagnosis of leiomyosarcoma. Reverse transcription-polymerase chain reaction showed the presence of JAZF1-SUZ12 fusion transcripts, and this highlights the broad morphologic and immunophenotypic spectrum of endometrial stromal sarcoma. Read More

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http://dx.doi.org/10.1177/1066896918767547DOI Listing
September 2018
36 Reads

Radiation-induced leiomyosarcoma of the rectum after cervical cancer treatment.

Rev Gastroenterol Mex 2018 Oct - Dec;83(4):465-467. Epub 2018 Feb 10.

Departamento de Piel y Partes Blandas, Instituto Nacional de Cancerología, Ciudad de México, México.

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http://dx.doi.org/10.1016/j.rgmx.2017.06.001DOI Listing
April 2019
5 Reads

[A Case of Leiomyosarcoma of the Small Intestine with Intestinal Hemorrhage Due to Intraluminal Penetration].

Gan To Kagaku Ryoho 2017 Nov;44(12):1068-1070

Dept. of Surgery, Tohoku University Graduate School of Medicine.

A 40-year-old man was referred to our hospital because of severe anemia and small intestinal tumor revealed by computed tomography. The enteroscopy exam showed the intraluminal penetration of the tumor, which was considered as a cause of anemia. Although emergency operation was performed laparoscopically, intraoperative findings indicated tumor invasion into peritoneum, and we converted from laparoscopic surgery to open surgery that included concomitant peritoneum resection. Read More

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November 2017
22 Reads

Spontaneous rupture of uterine smooth muscle tumour presenting acute abdominal pain and haemoperitoneum.

BMJ Case Rep 2018 Jan 3;2018. Epub 2018 Jan 3.

Chiba Aiyukai Memorial Hospital, Chiba, Japan.

Uterine smooth muscle tumours are histologically categorised into benign leiomyoma, malignant leiomyosarcoma or smooth muscle tumours of uncertain malignant potentials (STUMPs). Common symptoms of uterine tumours are hypermenorrhea, dysmenorrhea, lumbago or irregular genital bleeding. We experienced a case of uterine tumour with atypical clinical behaviour. Read More

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http://dx.doi.org/10.1136/bcr-2017-222806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775777PMC
January 2018
10 Reads

Leiomyomatosis peritonealisis disseminata: Two unusual cases with literature review.

J Gynecol Obstet Hum Reprod 2018 Feb 28;47(2):89-94. Epub 2017 Nov 28.

Chirurgie digestive, CHU de Caen, 14000 Caen, France.

Background: Leiomyomatosis peritonealis disseminata (LPD) is a rare benign disease characterized by numerous smooth muscle-like cell nodules disseminated among the abdominal cavity. The pathogenesis of LPD is not well-known; one hypothesis, widely reported, is parasitic LPD (after uterine myoma surgery). The role of hormonal status has been raised without any evidence yet confirmed. Read More

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http://dx.doi.org/10.1016/j.jogoh.2017.11.011DOI Listing
February 2018
8 Reads

Surgical Management of Primary Retroperitoneal Sarcomas: Rationale for Selective Organ Resection.

Ann Surg Oncol 2018 Jan 24;25(1):98-106. Epub 2017 Oct 24.

Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.

Background: Recently, some have argued for routine resection of adjacent but uninvolved organs in patients with retroperitoneal sarcoma (RPS) without stipulating the rationale for such organ resection (beyond the need to achieve a macroscopically complete resection) or examining histopathologic organ invasion (HOI). This study reviewed the authors' experience with primary RPS to investigate the rate and rationale for individual organ resection and the rate of HOI.

Methods: Operative and pathology reports for patients with primary RPS who underwent resection at our institution were retrospectively reviewed. Read More

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http://dx.doi.org/10.1245/s10434-017-6136-4DOI Listing
January 2018
16 Reads

Integrated genome analysis of uterine leiomyosarcoma to identify novel driver genes and targetable pathways.

Int J Cancer 2018 03 7;142(6):1230-1243. Epub 2017 Nov 7.

Department of Oncology, Gynecologic Oncology, KU Leuven (University of Leuven), Leuven, 3000, Belgium.

Uterine leiomyosarcomas (uLMS) are rare, aggressive malignancies for which limited treatment options are available. To gain novel molecular insights into uLMS and identify potential novel therapeutic targets, we characterized 84 uLMS samples for genome-wide somatic copy number alterations, mutations, gene fusions and gene expression and performed a data integration analysis. We found that alterations affecting TP53, RB1, PTEN, MED12, YWHAE and VIPR2 were present in the majority of uLMS. Read More

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http://dx.doi.org/10.1002/ijc.31129DOI Listing
March 2018
48 Reads

Rare case of primary leiomyosarcoma of sigmoid mesocolon.

BMJ Case Rep 2017 Sep 15;2017. Epub 2017 Sep 15.

Department of Surgery, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

We experienced a rare case of primary leiomyosarcoma of sigmoid mesentery. A 45-year-old woman was presented to us with left iliac fossa mass and discomfort for 4-month duration. CT scan of abdomen and pelvis revealed a huge mass 14 cm×14 cm×16 cm occupying left iliac fossa mimicked having a large left ovarian carcinoma. Read More

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http://dx.doi.org/10.1136/bcr-2017-219826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614005PMC
September 2017
6 Reads

Pediatric liver transplantation for hepatocellular cancer and rare liver malignancies: US multicenter and single-center experience (1981-2015).

Liver Transpl 2017 12;23(12):1577-1588

Thomas E. Starzl Transplantation Institute, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA.

A tenth of all pediatric liver transplantations (LTs) are performed for unresectable liver malignancies, especially the more common hepatoblastoma (HBL). Less understood are outcomes after LT for the rare hepatocellular carcinoma, nonhepatoblastoma embryonal tumors (EMBs), and slow growing metastatic neuroendocrine tumors of childhood. Pediatric LT is increasingly performed for rare unresectable liver malignancies other than HBL. Read More

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http://dx.doi.org/10.1002/lt.24847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725660PMC
December 2017
67 Reads

Synchronous coexistence of liver metastases from cecal leiomyosarcoma and rectal adenocarcinoma: A case report.

World J Gastroenterol 2017 Mar;23(9):1725-1734

Hideki Aoki, Takashi Arata, Masashi Utsumi, Yutaka Mushiake, Tomoyoshi Kunitomo, Isao Yasuhara, Fumitaka Taniguchi, Koh Katsuda, Kohji Tanakaya, Hitoshi Takeuchi, Department of Surgery, Iwakuni Clinical Center, Yamaguchi 740-8510, Japan.

Multiple liver tumors represent a challenging condition for abdominal surgeons both in the selection of technique and the rarity of diagnosis. There are no case reports on co-existence of liver metastases from both intestinal leiomyosarcoma and adenocarcinoma. The patient described in this report successfully underwent resection of both primary lesions and liver metastases in combination with chemotherapy. Read More

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http://www.wjgnet.com/1007-9327/full/v23/i9/1725.htm
Publisher Site
http://dx.doi.org/10.3748/wjg.v23.i9.1725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340824PMC
March 2017
29 Reads

A rare case of small bowel leiomyosarcoma presenting with acute gastro-intestinal bleeding.

BJR Case Rep 2017 22;3(2):20160089. Epub 2016 Dec 22.

Department of Radiology, Medisch Centrum Haaglanden, The Hague, Netherlands.

A 62-year-old Turkish female was admitted to our hospital with acute, progressive melena. Gastroscopy and colonoscopy could not reveal the cause of the melena. Subsequent CT angiography demonstrated a large, exophytic mass in the ileocecal junction as a source of the haemorrhage, leading to urgent laparotomy and resection. Read More

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https://www.birpublications.org/doi/10.1259/bjrcr.20160089
Publisher Site
http://dx.doi.org/10.1259/bjrcr.20160089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159237PMC
December 2016
13 Reads

[A pseudotumoral lesion revealing Meckel's diverticulum].

Arch Pediatr 2016 Nov 28;23(11):1157-1160. Epub 2016 Sep 28.

Service d'anatomie et cytologie pathologiques, hôpital Armand-Trousseau, AP-HP, 26, avenue du Dr-Arnold-Netter, 75012 Paris, France.

Introduction: Meckel's diverticulum is a common malformation in children, usually asymptomatic, with complications in only 20% of cases. Exceptionally, a tumor can develop in Meckel's diverticulum in children, particularly Burkitt's lymphoma; in adults it can develop into a gastrointestinal stromal tumor, a leiomyosarcoma, or a neuroendocrine tumor such as a carcinoid tumor. The diagnosis of inflammatory pseudotumor following an insidious perforation is rare. Read More

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http://dx.doi.org/10.1016/j.arcped.2016.08.002DOI Listing
November 2016
59 Reads

Rectal Bleeding Due to Leiomyosarcoma.

Clin Gastroenterol Hepatol 2017 01 12;15(1):e1-e2. Epub 2016 Aug 12.

Department of Gastroenterology, Campbelltown Hospital, Western Sydney University, New South Wales, Sydney, Australia; Department of Anatomical Pathology, Liverpool Hospital, Western Sydney University, New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1016/j.cgh.2016.08.008DOI Listing
January 2017
15 Reads

Unusual evolution of leiomyosarcoma of the rectum: a case report and review of the literature.

J Med Case Rep 2016 Sep 15;10(1):249. Epub 2016 Sep 15.

Department of Radiotherapy, National Institute of Oncology, University Mohammed V, Rabat, Morocco.

Background: Leiomyosarcoma of the rectum is a rare entity that comprises less than 0.1 % of all rectal malignancies. Given the uncommon nature of this tumor and the controversy about its treatment we report one case and review the literature in an attempt to report a particular evolution and to discuss the most appropriate treatment. Read More

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http://dx.doi.org/10.1186/s13256-016-1047-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025574PMC
September 2016
8 Reads

A very rare case of a small bowel leiomyosarcoma leading to ileocaecal intussusception treated with a laparoscopic resection: a case report and a literature review.

World J Surg Oncol 2016 Feb 24;14(1):48. Epub 2016 Feb 24.

Department of General, Gastroenterological and Oncologic Surgery, Medical University of Warsaw, ul. Banacha 1a, 02-097, Warsaw, Poland.

Background: Small bowel tumours are rare and comprise less than 2% of all primary gastrointestinal neoplasms. Among these tumours, a leiomyosarcoma belonging to soft tissue sarcomas is extremely rare and accounts for about 1 % of malignant mesenchymal lesions in the gastrointestinal tract. Due to its aggressive nature and slow growth, it is often diagnosed at the late stage when curative treatment is impossible. Read More

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http://www.wjso.com/content/14/1/48
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http://dx.doi.org/10.1186/s12957-016-0798-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765121PMC
February 2016
19 Reads

Gastrointestinal (GI) leiomyosarcoma (LMS) case series and review on diagnosis, management, and prognosis.

Med Oncol 2016 Feb 20;33(2):20. Epub 2016 Jan 20.

Department of Internal Medicine, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, Beirut, Lebanon.

This review of 76 gastrointestinal (GI) leiomyosarcoma (LMS) cases that include 11 cases from the American University of Beirut Medical Center represents, to our knowledge, the largest number of combined GI LMS cases reported. The age range of GI LMS is variable, and the presentation is non-specific, making pathological diagnosis essential. LMSs usually lack CD117 and CD 34 mutations and are usually positive for smooth muscle cell markers. Read More

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http://dx.doi.org/10.1007/s12032-016-0730-3DOI Listing
February 2016
16 Reads

Laparoscopic Hysterectomy for Uterine Fibroids: Is it Safe?

Clin Obstet Gynecol 2016 Mar;59(1):66-72

*Department of Obstetrics and Gynecology †Division of Minimally Invasive Gynecologic Surgery, Brigham and Women's Hospital, Boston, Massachusetts.

As more complex cases and larger uterine specimens are able to be managed with minimally invasive surgery, the limitations of tissue retrieval with these methods are of increasing concern. Risks of morcellator-related injury, tissue dissemination, or fragmentation must be weighed against increased morbidity of abdominal approach to hysterectomy. In an effort to mitigate the risks of tissue morcellation, containment system use must be considered when fragmenting a specimen, either with power morcellation or a manual technique via the vagina or minilaparotomy. Read More

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http://dx.doi.org/10.1097/GRF.0000000000000165DOI Listing
March 2016
14 Reads

Clinical presentation and management of gastro-intestinal and pancreatic secondary metastatic tumors.

J BUON 2015 Jul-Aug;20(4):1009-14

2nd Department of Surgery, "Aretaieio" Hospital, University of Athens Medical School, Athens, Greece.

Purpose: As progress regarding the treatment has occurred over recent years in oncology, more patients with metastatic disease are presented for diagnosis and further management. The purpose of this study was to reveal the incidence, location and to describe the clinical characteristics and outcome in a series of patients diagnosed with pancreatic, small and large bowel metastatic tumors that underwent metastasectomy.

Methods: A total of 12 patients (7 male and 5 female) diagnosed with extrahepatic gastrointestinal (GI) and pancreatic metastases from 2001 to 2013 were operated for resection of secondary metastatic tumors to the small and large bowel and the pancreas. Read More

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November 2015
62 Reads

Perineal approach for surgical treatment in a patient with retro-rectal tumor: a case report and review of the literature.

BMC Res Notes 2015 Sep 24;8:470. Epub 2015 Sep 24.

Department of Digestive Surgery, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Mohammed V University, Rabat, Morocco.

Background: Retrorectal tumors in adults are very rare and little known condition. These tumors, often misdiagnosed or mistreated, should be completely excised because of the potential for malignancy or infection. A suitable operative approach is the key to the successful surgical management. Read More

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http://dx.doi.org/10.1186/s13104-015-1457-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581409PMC
September 2015
17 Reads

[Cancer and wall growths in the mesenchymal gastrointestinal tract].

Pol J Pathol 2014 Dec;65(4 Suppl 1):S90-106

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December 2014
11 Reads

Gastrointestinal stromal tumour presenting as palpable abdominal mass: A rare entity.

World J Gastrointest Surg 2015 Jun;7(6):98-101

Manoj R Bhambare, Jayashri S Pandya, Sudatta B Waghmare, Tilakdas S Shetty, Department of General Surgery, Topiwala National Medical College and Bai Yamunabai Laxman Nair Hospital, Mumbai 400008, India.

Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumour of gastro-intestinal tract. Annual incidence of GIST in United States is approximately 3000-4000. Clinical presentation of GIST varies with location and size of tumour but GIST presenting with palpable abdominal mass is rare. Read More

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http://dx.doi.org/10.4240/wjgs.v7.i6.98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478562PMC
June 2015
14 Reads

Sinonasal inflammatory myofibroblastic pseudotumor (plasma cell granuloma).

Kulak Burun Bogaz Ihtis Derg 2015 ;25(3):174-8

Department of Pathology, Medical Faculty of Mersin University, 33100 Zeytinlibahçe, Mersin, Turkey.

Inflammatory myofibroblastic pseudotumor (plasma cell granuloma) is a soft tissue lesion consisting of myofibroblasts, mature lymphocytes, histiocytes, plasma cells, eosinophils, and extracellular collagen. Various sites in the body may harbor these lesions. Lungs, omentum, intestines, mesentery, and urinary system are the most susceptible areas. Read More

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http://dx.doi.org/10.5606/kbbihtisas.2015.04875DOI Listing
June 2016
20 Reads

Diaphragm disease of the small intestine: an interesting case report.

Int J Surg Pathol 2015 Jun 18;23(4):322-4. Epub 2014 Dec 18.

Airedale Hospital, Steeton, UK.

Diaphragm disease of small intestine usually presents with nonspecific clinical features. Radiological investigations often fail to differentiate it from small intestinal tumors and inflammatory bowel disease. It is therefore diagnosed on final histology after surgical resection. Read More

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http://dx.doi.org/10.1177/1066896914563392DOI Listing
June 2015
18 Reads

What is your diagnosis? Leiomyosarcoma.

J Am Vet Med Assoc 2015 Jan;246(1):51-3

Center for Veterinary Health Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078.

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http://avmajournals.avma.org/doi/abs/10.2460/javma.246.1.51
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http://dx.doi.org/10.2460/javma.246.1.51DOI Listing
January 2015
24 Reads

Small intestinal gastrointestinal stromal tumor in a young adult woman: a case report and review of the literature.

J Med Case Rep 2014 Sep 28;8:321. Epub 2014 Sep 28.

Institute of Pathology, Faculty of Medicine, University of Prishtina, Mother Theresa Street NN, 10 000 Prishtina, Kosovo.

Introduction: Gastrointestinal stromal tumor is the most common sarcoma of the gastrointestinal tract. We report a case of gastrointestinal stromal tumor in a small intestine, initially suspected for leiomyosarcoma given that gastrointestinal stromal tumors in young adult patients are limited due to their rarity.

Case Presentation: A 30-year-old Caucasian ethnic Albanian woman from Kosovo presented with abdominal pain, nausea and vomiting. Read More

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http://www.jmedicalcasereports.com/content/pdf/1752-1947-8-3
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http://www.jmedicalcasereports.com/content/8/1/321
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http://dx.doi.org/10.1186/1752-1947-8-321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188407PMC
September 2014
41 Reads

Metastasis of gastrointestinal stromal tumor to skeletal muscle: a case report.

J Med Case Rep 2014 Jul 18;8:256. Epub 2014 Jul 18.

Department of Orthopaedic Surgery, University of Toyama, 2630 Sugitani, Toyama, Toyama 930-0194, Japan.

Introduction: Gastrointestinal stromal tumor is the most common malignant mesenchymal tumor of the gastrointestinal tract. The most common sites of metastasis are the liver and the peritoneum, but gastrointestinal stromal tumors rarely metastasize to the skeletal muscles. Only three cases of gastrointestinal stromal tumor metastasizing to skeletal muscle have been reported in the English literature. Read More

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http://dx.doi.org/10.1186/1752-1947-8-256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112972PMC
July 2014
14 Reads

Bowel perforation associated with temsirolimus use in a recently irradiated patient.

Am J Health Syst Pharm 2014 Jun;71(11):919-23

Claire M. Mach, Pharm.D., is Assistant Professor, College of Pharmacy, University of Houston, and Division of Gynecologic Oncology, Baylor College of Medicine, Houston, TX. Anze Urh, M.D., is Obstetrics and Gynecology Resident, Division of Gynecologic Oncology, Baylor College of Medicine. Matthew L. Anderson, M.D., Ph.D., is Assistant Professor and Director of Clinical and Translational Research, Division of Gynecologic Oncology and Dan L. Duncan Cancer Center, Baylor College of Medicine.

Purpose: A probable case of bowel perforation associated with temsirolimus use in a patient with uterine leiomyosarcoma is reported.

Summary: A 45-year-old Hispanic woman reported acute abdominal pain one day after receiving her third weekly i.v. Read More

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http://dx.doi.org/10.2146/ajhp130145DOI Listing
June 2014
13 Reads

Idiopathic phlebosclerotic colitis: a rare entity of chronic ischemic colitis.

Korean J Gastroenterol 2014 Mar;63(3):183-6

Department of Internal Medicine, Hanyang University College of Medicine, 222 Wangsimni-ro, Seongdong-gu, Seoul 133-791, Korea.

Colonic wall thickening is frequently encountered in various conditions, from acute or chronic inflammatory disease to colorectal carcinoma. Colonic wall thickening may be accompanied by calcifications in mucinous adenocarcinoma of the colon, leiomyosarco-ma of the colon, schistosomiasis japonica, and phlebosclerotic colitis. Phlebosclerotic colitis is a rare entity of chronic ischemic colitis associated with sclerosis and fibrosis of mesenteric veins. Read More

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http://dx.doi.org/10.4166/kjg.2014.63.3.183DOI Listing
March 2014
19 Reads

A case of benign schwannoma of the ascending colon treated with laparoscopic-assisted wedge resection.

Int Surg 2013 Oct-Dec;98(4):315-8

1 Department of Surgery, Korea University Anam Hospital, Seoul, Korea.

Isolated colonic schwannomas are rare gastrointestinal mesenchymal tumors. Only a small number of cases have been reported. Occurrence of these tumors is more common in the stomach than in the large intestine. Read More

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http://dx.doi.org/10.9738/INTSURG-D-13-00015.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829056PMC
February 2015
20 Reads

[Colonic intussusception by leiomyosarcoma].

Rev Gastroenterol Peru 2013 Jul-Sep;33(3):251-4

Departamento del Aparato Digestivo, Hospital Nacional Edgardo Rebagliati Martins, EsSalud. Lima, Perú.

Unlabelled: We report the case of female patient, 34 years old, occupation Secretary.

Background: Polycystic ovary and chronic anemia. No family history of cancer. Read More

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August 2014
31 Reads

Gastrointestinal leiomyosarcoma in a pygmy sperm whale (Kogia breviceps).

J Zoo Wildl Med 2013 Sep;44(3):744-8

Department of Infectious Diseases and Pathology, College of Veterinary Medicine, University of Florida, Gainesville, Florida 32612, USA.

An adult male pygmy sperm whale (Kogia breviceps) was stranded within a tidal pool on Fernandina Beach on the north Florida Atlantic coast (USA) and expired soon after discovery. Necropsy findings included a small intestinal mass markedly expanding the intestinal wall and partially obstructing the lumen. This finding likely led to the malnutrition and ultimately the stranding of this whale. Read More

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http://dx.doi.org/10.1638/2012-0147R.1DOI Listing
September 2013
39 Reads

Leiomyosarcoma of the sigmoid colon: a rare cause of intestinal intussusception.

J Gastrointest Cancer 2014 Dec;45 Suppl 1:6-9

Department of Gastroenterology, Pforzheim Hospital, Kanzlerstr. 2-6, 75175, Pforzheim, Germany,

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http://dx.doi.org/10.1007/s12029-013-9520-8DOI Listing
December 2014
17 Reads

Patient with two secondary somatic-type malignancies in a late recurrence of a testicular non-seminoma: illustration of potential and flaw of the cancer stem cell therapy concept.

Int J Dev Biol 2013 ;57(2-4):153-7

Department of Pathology, Erasmus University Medical Center, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

Here, we report the case of a patient with a non-seminoma of the left testicle, with an intestinal-type adenocarcinoma and a low grade leiomyosarcoma in a late recurrence 19 years after initial diagnosis. The history of the patient, alive with disease 21 years after initial treatment, illustrates the potential and flaw of the cancer stem cell therapy concept. In addition, it is proposed that residual mature teratoma can be regarded as normalization of cancer due to embryonic patterning, and the development of a secondary somatic-type malignancy as failure of normalization. Read More

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http://dx.doi.org/10.1387/ijdb.130141joDOI Listing
January 2014
30 Reads