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    Molecular, morphological and experimental assessment of the life cycle of Posthodiplostomum nanum Dubois, 1937 (Trematoda: Diplostomidae) from Brazil, with phylogenetic evidence of the paraphyly of the genus Posthodiplostomum Dubois, 1936.
    Infect Genet Evol 2018 May 18;63:95-103. Epub 2018 May 18.
    Departament of Parasitology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address:
    Species of the genus Posthodiplostomum are intestinal parasites of piscivorous birds with worldwide distribution. Recent molecular surveys have focused on developmental stages from vertebrate hosts, with few sequences from larvae found in molluscs. Moreover, most published molecular data are from collections in North America, Europe and Asia, and there are no data for South American species. Read More

    Brachylaima asakawai sp. nov. (Trematoda: Brachylaimidae), a rodent intestinal fluke in Hokkaido, Japan, with a finding of the first and second intermediate hosts.
    Parasitol Int 2018 Apr 27;67(5):565-574. Epub 2018 Apr 27.
    Mie University Graduate School, Faculty of Bioresources, Tsu, Mie 514-8507, Japan.
    In the 1970's and 1980's, an unknown species of the genus Brachylaima (Trematoda: Brachylaimidae) had been recorded from the intestines of Rattus norvegicus and Apodemus speciosus in Hokkaido, Japan. The rodent fluke was characteristic in extending a bilateral vitellarium till the level of posterior margin of anterior testis and in keeping almost the same-sized spherical ovary and testes. In this study, the rodent fluke was rediscovered from A. Read More

    Antischistosomal and anti-inflammatory activity of garlic and allicin compared with that of praziquantel in vivo.
    BMC Complement Altern Med 2018 Apr 27;18(1):135. Epub 2018 Apr 27.
    Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.
    Background: Schistosomiasis is an acute and chronic zoonotic parasitic disease caused by trematode worms. The host inflammatory response to schistosome eggs leads to perioval granulomata formation, mainly in the liver and intestine. This study investigated the potential antischistosomal and anti-inflammatory activity of both garlic extract and allicin on liver fibrotic markers in BALB/c mice with schistosomiasis (S. Read More

    Associations of intestinal helminth infections with health parameters of spring-migrating female lesser scaup (Aythya affinis) in the upper Midwest, USA.
    Parasitol Res 2018 Jun 25;117(6):1877-1890. Epub 2018 Apr 25.
    Frank C. Bellrose Waterfowl Research Center, Forbes Biological Station, Illinois Natural History Survey, Prairie Research Institute, University of Illinois Urbana-Champaign, 20003 CR 1770E, Havana, IL, 62644, USA.
    Thousands of lesser scaup (Aythya affinis) die during spring and fall migrations through the upper Midwest, USA, from infections with Cyathocotyle bushiensis and Sphaeridiotrema spp. (Class: Trematoda) after ingesting infected intermediate hosts, such as non-native faucet snails (Bithynia tentaculata). The lesser scaup is a species of conservation concern and is highly susceptible to these infections. Read More

    Utilization of real time PCR for the assessment of egg burden in the organs of Schistosoma japonicum experimentally infected mice.
    Exp Parasitol 2018 Jun 18;189:61-65. Epub 2018 Apr 18.
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan. Electronic address:
    Schistosoma japonicum, causing zoonotic intestinal schistosomiasis, is found in China, the Philippines and parts of Indonesia. Severe disease manifestations are basically due to the deposition of eggs in some vital organs such as the liver, spleen and brain. Traditionally, histopathological microscopic examination of the egg burden was used to evaluate the intensity of infection in the affected organs. Read More

    The life cycle of a zoonotic parasite reassessed: Experimental infection of Melanoides tuberculata (Mollusca: Thiaridae) with Centrocestus formosanus (Trematoda: Heterophyidae).
    PLoS One 2018 6;13(4):e0194161. Epub 2018 Apr 6.
    Department of Parasitology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
    Centrocestus formosanus is a foodborne intestinal trematode that is native to Asia and has been introduced into the Americas and Europe. Although there are several studies of C. formosanus in definitive vertebrate hosts (birds and mammals, including humans), and in intermediate vertebrate hosts (fish and amphibians), there is little published information regarding interaction with its transmitting mollusc. Read More

    Infection in Two Residents of Savannakhet Province, Lao PDR.
    Korean J Parasitol 2018 Feb 28;56(1):75-79. Epub 2018 Feb 28.
    Department of Parasitology, Korea University College of Medicine, Seoul 02841, Korea.
    Adult specimens of (Garrison, 1908) Odhner, 1911 (Trematoda: Echinostomatidae) were recovered from 2 riparian people who resided along the Mekong River in Savannakhet Province, Lao PDR. In fecal examinations done by the Kato-Katz technique, they revealed echinostome eggs together with eggs of (and minute intestinal fluke eggs) and hookworms. To recover the adult flukes, they were treated with praziquantel 30-40 mg/kg in a single dose and purged with magnesium salts. Read More

    Study of diagnostic accuracy of Helmintex, Kato-Katz, and POC-CCA methods for diagnosing intestinal schistosomiasis in Candeal, a low intensity transmission area in northeastern Brazil.
    PLoS Negl Trop Dis 2018 03 8;12(3):e0006274. Epub 2018 Mar 8.
    Laboratório de Biologia Parasitária, School of Sciences, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
    Control initiatives have successfully reduced the prevalence and intensity of schistosomiasis transmission in several localities around the world. However, individuals that release low numbers of eggs in their feces may not be detected by classical methods that are limited by low sensitivity. Given that accurate estimates of prevalence are key to implementing planning control actions for the elimination of schistosomiasis, new diagnostic tools are needed to effectively monitor infections and confirm transmission interruption. Read More

    Evaluation of diagnostic methods for the detection of intestinal schistosomiasis in endemic areas with low parasite loads: Saline gradient, Helmintex, Kato-Katz and rapid urine test.
    PLoS Negl Trop Dis 2018 02 22;12(2):e0006232. Epub 2018 Feb 22.
    Departamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.
    Background: In some tropical countries, such as Brazil, schistosomiasis control programs have led to a significant reduction in the prevalence and parasite burden of endemic populations. In this setting, the Kato-Katz technique, as the standard diagnostic method for the diagnosis of Schistosoma mansoni infections, which involves the analysis of two slides from one fecal sample, loses its sensitivity. As a result, a significant number of infected individuals are not detected. Read More

    Adaptation of the secretome of Echinostoma caproni may contribute to parasite survival in a Th1 milieu.
    Parasitol Res 2018 Apr 12;117(4):947-957. Epub 2018 Feb 12.
    Departamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Avda. Vicent Andrés Estellés s/n, Burjassot, 46100, Valencia, Spain.
    Echinostoma caproni (Trematoda: Echinostomatidae) is an intestinal trematode, broadly employed to study the host-dependent mechanisms that govern the evolution of intestinal helminth infections. Resistance against E. caproni homologous secondary infections has been reported in mice and appears to be related to the generation of a local Th2 response, whereas Th1 responses promote the development of chronic primary infections. Read More

    Diet assimilation trends and host-parasite relationships in two species of sunfish (Lepomis) revealed by stable isotope analyses of multiple tissues.
    Parasitol Res 2018 Apr 2;117(4):1043-1049. Epub 2018 Feb 2.
    Formerly School of Environmental Studies, Queen's University, Kingston, Ontario, Canada.
    White grub flukes, Posthodiplostomum minimum centrarchi (Trematoda), and hookworms Pomphorhynchus bulbocolli (Acanthocephala) are common internal parasites for many North American freshwater fishes. P. minimum are found as cysts in internal organ tissues, while P. Read More

    A new species of Steringotrema Odhner, 1911 (Trematoda: Fellodistomidae) from the New Zealand sole Peltorhamphus novaezeelandiae Günther off Kaka point in the Catlins, South Island, New Zealand.
    Syst Parasitol 2018 Mar 25;95(2-3):213-222. Epub 2018 Jan 25.
    Ecology Degree Programme, University of Otago, P.O. Box 56, Dunedin, 9054, New Zealand.
    As a part of a comprehensive survey of macroparasites of commercially exploited fish species off the coast of Otago, New Zealand, the parasite fauna of the New Zealand sole Peltorhamphus novaezeelandiae Günther was recently studied. Steringotrema robertpoulini n. sp. Read More

    A new genus and species of turtle blood fluke (Digenea: Schistosomatoidea) from the Mekong snail-eating turtle, Malayemys subtrijuga (Schlegel & Müller) (Testudines: Geoemydidae) in Vietnam, with a reassessment of related Asiatic turtle blood flukes and molecular phylogeny.
    Syst Parasitol 2018 Mar 22;95(2-3):133-145. Epub 2018 Jan 22.
    Aquaculture & Aquatic Sciences and Aquatic Parasitology Laboratory, School of Fisheries, Auburn University, 203 Swingle Hall, Auburn, AL, 36849, USA.
    Platt sinuosus Roberts & Bullard n. g., n. Read More

    Assessing the benefits of five years of different approaches to treatment of urogenital schistosomiasis: A SCORE project in Northern Mozambique.
    PLoS Negl Trop Dis 2017 12 8;11(12):e0006061. Epub 2017 Dec 8.
    Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.
    Background: In Mozambique, schistosomiasis is highly endemic across the whole country. The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) coordinates a five-year study that has been implemented in various African countries, including Mozambique. The overall goal of SCORE was to better understand how to best apply preventive chemotherapy with praziquantel (PZQ) for schistosomiasis control by evaluating the impact of alternative treatment approaches. Read More

    Kunitz-type protease inhibitor as a vaccine candidate against schistosomiasis mansoni.
    Int J Infect Dis 2018 Jan 8;66:26-32. Epub 2017 Nov 8.
    Molecular Parasitology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
    Objective: The aim of this study was to develop a vaccine against schistosomiasis, which is a major challenge due to the complex lifecycle of the causative schistosome parasite.

    Methods: SmKI-1 is a 16-kDa Kunitz-type protease inhibitor present in the excretory-secretory products and tegument of adult worms and eggs of Schistosoma mansoni. Two independent vaccine trials were performed in mice to determine the efficacy of rSmKI-1 in developing protective immunity. Read More

    Intestinal Parasite Infections among Inhabitants in Yanbian Prefecture, Jilin Province, China.
    Korean J Parasitol 2017 Oct 31;55(5):579-582. Epub 2017 Oct 31.
    Division of Vectors and Parasitic Diseases, Centers for Disease Control and Prevention, Osong 28159, Korea.
    To investigate the prevalence of intestinal parasite infections in Yanbian Prefecture, Jilin Province, China, epidemiological surveys were conducted on a collaboration basis between the Korean Centers for Disease Control and Prevention and the Yanbian Center for Disease Control and Prevention. A total of 8,396 (males 3,737 and females 4,659) stool samples were collected from 8 localities and examined with the formalin-ether sedimentation technique, and additionally examined with the cellotape anal swab to detect Enterobius vermicularis eggs. The overall rate of intestinal parasites was 1. Read More

    New Record of Aspidogaster ijimai Kawamura, 1913 (Trematoda: Aspidogastridae) from Cyprinus carpio in Korea.
    Korean J Parasitol 2017 Oct 31;55(5):575-578. Epub 2017 Oct 31.
    Department of Parasitology, Medical Research Institute and Parasite Resource Bank, Chungbuk National University School of Medicine, Cheongju 28644, Korea.
    Aspidogastrid trematodes (Subclass Aspidogastrea) are a relatively small group with a characteristic adhesive disc and parasitize in a variety of cold-blooded hosts. Until now, only 2 species in the genus Cotylaspis, i.e. Read More

    Molecular discrimination of Opisthorchis-like eggs from residents in a rural community of central Thailand.
    PLoS Negl Trop Dis 2017 Nov 2;11(11):e0006030. Epub 2017 Nov 2.
    Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
    Background: Opisthorchis viverrini infection is a major public health problem in northern and northeastern Thailand. The chronic infection of O. viverrini is related to cholangiocarcinoma which causes high mortality in endemic areas. Read More

    Schistosoma mansoni: In vivo evaluation of Phyllanthus amarus hexanic and ethanolic extracts.
    Exp Parasitol 2017 Dec 23;183:56-63. Epub 2017 Oct 23.
    Biology Institute, Animal Biology Department, Campinas State University (UNICAMP), SP, Brazil. Electronic address:
    Human schistosomiasis is an important neglected tropical disease caused by blood flukes of the genus Schistosoma and is responsible for more than 280,000 deaths annually. Treatment for this disease relies currently on a single drug, praziquantel (PZQ). Concerns regarding PZQ resistance and insensitivity of juvenile schistosomes have increased the interest in resorting to medicinal plants for alternative drug therapies. Read More

    Cross-species prophylactic efficacy of Sm-p80-based vaccine and intracellular localization of Sm-p80/Sm-p80 ortholog proteins during development in Schistosoma mansoni, Schistosoma japonicum, and Schistosoma haematobium.
    Parasitol Res 2017 Nov 12;116(11):3175-3188. Epub 2017 Oct 12.
    Center for Tropical Medicine and Infectious Diseases, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
    Schistosomiasis remains a major global health problem. Despite large-scale schistosomiasis control efforts, clear limitations such as possible emergence of drug resistance and reinfection rates highlight the need for an effective schistosomiasis vaccine. Schistosoma mansoni large subunit of calpain (Sm-p80)-based vaccine formulations have shown remarkable efficacy in protecting against S. Read More

    [Food-borne trematodiases].
    Rev Med Suisse 2017 Oct;13(578):1741-1744
    Clinique de médecine, HFR Fribourg - Hôpital cantonal, 1708 Fribourg.
    Food-borne trematodiases (flukes) are transmitted through the consumption of contaminated undercooked aquatic food. Infections are most prevalent in Southeast Asia and Latin America, but might occur anywhere due to food trade, international travel, human migration. Clinical manifestations are hepatobiliary, intestinal, and pleuropulmonary. Read More

    Estimating sensitivity of the Kato-Katz technique for the diagnosis of Schistosoma mansoni and hookworm in relation to infection intensity.
    PLoS Negl Trop Dis 2017 Oct 4;11(10):e0005953. Epub 2017 Oct 4.
    Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.
    The Kato-Katz technique is the most widely used diagnostic method in epidemiologic surveys and drug efficacy trials pertaining to intestinal schistosomiasis and soil-transmitted helminthiasis. However, the sensitivity of the technique is low, particularly for the detection of light-intensity helminth infections. Examination of multiple stool samples reduces the diagnostic error; yet, most studies rely on a single Kato-Katz thick smear, thus underestimating infection prevalence. Read More

    Helminth parasites of the endangered hooded grebe, Podiceps gallardoi, from Patagonia Argentina, with the description of two new digenean species.
    J Helminthol 2017 Oct 4:1-9. Epub 2017 Oct 4.
    División Zoología Invertebrados,Museo de La Plata,Facultad de Ciencias Naturales y Museo,Universidad Nacional de La Plata (UNLP),Paseo del Bosque S/N°, 1900 La Plata,Buenos Aires Province,Argentina.
    In March 2011, a predator killed 33 hooded grebes, Podiceps gallardoi Rumboll (Podicipedidae), a critically endangered species, in a nesting colony at El Cervecero Lake, Santa Cruz Province, Argentina. The viscera of ten birds were examined for helminths. Two new species of Trematoda were recovered from the intestines. Read More

    Immunolocalization and immunodetection of the excretory/secretory (ES) antigens of Fasciola gigantica.
    PLoS One 2017 3;12(10):e0185870. Epub 2017 Oct 3.
    Section of Parasitology, Department of Zoology, Aligarh Muslim University, Aligarh, India.
    The digenetic trematode Fasciola gigantica is a parasite of great agricultural and economic importance. Along with Fasciola hepatica, F. gigantica incurs huge economic losses to the agricultural sector. Read More

    Perceptions about interventions to control schistosomiasis among the Lake Victoria island communities of Koome, Uganda.
    PLoS Negl Trop Dis 2017 Oct 2;11(10):e0005982. Epub 2017 Oct 2.
    Social Aspects of Health Programme, Medical Research Council/ Uganda Virus Research Institute (MRC/ UVRI) Uganda Research Unit, Uganda Virus Research Institute, Entebbe, Uganda.
    Background: Praziquantel-based mass treatment is the main approach to controlling schistosomiasis mansoni in endemic areas. Interventions such as provision and use of safe water, minimising contact with infested water, disposal of stool in latrines and snail control provide key avenues to break the transmission cycle and can sustain the benefits of mass treatment in the long term. Efforts are also being made to develop a schistosomiasis vaccine which, if effective, might reduce the incidence of re-infection after treatment. Read More

    Insulin growth factor inhibitor as a potential new anti-schistosoma drug: An in vivo experimental study.
    Biomed Pharmacother 2017 Nov 19;95:1346-1358. Epub 2017 Sep 19.
    Department of Public Health and Community Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt. Electronic address:
    Background And Objective: Tyrphostin "AG1024" is an insulin growth factor-1 receptor (IGF-1R) inhibitor that displayed an effect on the viability of larval and mature schistosomes in vitro. We sought to investigate the possible in vivo role of AG1024 as a potential new anti-Schistosoma drug against immature and adult stages of Schistosoma mansoni and its effect on the degree of hepatic fibrosis and insulin pathway.

    Methods: The study included a control non-infected group and 5 groups of S. Read More

    Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model.
    PLoS Negl Trop Dis 2017 Sep 21;11(9):e0005942. Epub 2017 Sep 21.
    Merck Global Health Institute, Ares Trading S.A., a subsidiary of Merck KGaA (Darmstadt, Germany), Coinsins, Switzerland.
    After more than 40 years of use, Praziquantel (PZQ) still remains the drug of choice for the treatment of intestinal and urogenital schistosomiasis. Its anti-parasitic activity resides primarily in the (R)-enantiomer. Hitherto neither the molecular target nor the pharmacokinetic-pharmacodynamic relationship have been fully elucidated. Read More

    Preparation and investigation of P28GST-loaded PLGA microparticles for immunomodulation of experimental colitis.
    Int J Pharm 2017 Nov 18;533(1):26-33. Epub 2017 Sep 18.
    Univ. Lille, Inserm, CHU Lille, U1008 - Controlled Drug Delivery Systems and Biomaterials, F-59000 Lille, France. Electronic address:
    The aim of this work was to prepare and characterize (in vitro and in vivo) PLGA-based microparticles loaded with an enzymatic protein derived from the helminth parasite Schistosoma haematobium: glutathione S-transferase P28GST (P28GST). This protein is not only a promising candidate vaccine against schistosomiasis, it also exhibits interesting immunomodulating effects, which can be helpful for the regulation of inflammatory diseases. Helminths express a regulatory role on intestinal inflammation, and immunization by P28GST has recently been shown to be as efficient as infection to reduce inflammation in a murine colitis model. Read More

    A comparative study on the efficacy of praziquantel and albendazole in the treatment of urinary schistosomiasis in Adim, Cross River State, Nigeria.
    Int Health 2017 09;9(5):288-293
    Medical Microbiology/Parasitology Unit, Department of Medical Laboratory Science, University of Calabar, Cross River State, Nigeria.
    Background: Praziquantel (PZQ) is the current drug of choice for the treatment of urinary schistosomiasis in endemic areas. It is very efficacious, although the potential for the development of resistance has been reported in some endemic areas among human subjects and in animal studies. Its' limitation include high cost and administration of multiple numbers of tablets. Read More

    attenuates dextran sodium sulfate-induced colitis in mice reduction of endoplasmic reticulum stress.
    World J Gastroenterol 2017 Aug;23(31):5700-5712
    Department of Gastroenterology, Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
    Aim: To elucidate the impact of (.) infection on inflammatory bowel disease by studying the effects of exposure to cercariae on dextran sodium sulfate (DSS)-induced colitis.

    Methods: Infection was percutaneously established with 20 ± 2 cercariae of , and colitis was induced by administration of 3% DSS at 4 wk post infection. Read More

    Characterization of Echinostoma cinetorchis endoribonuclease, RNase H.
    Korean J Parasitol 2017 Aug 31;55(4):451-455. Epub 2017 Aug 31.
    Institute of Research and Development, Scorpiogen Co., Anseong 17579, Korea.
    Echinostoma cinetorchis is an oriental intestinal fluke causing significant pathological damage to the small intestine. The aim of this study was to determine a full-length cDNA sequence of E. cinetorchis endoribonuclease (RNase H; EcRNH) and to elucidate its molecular biological characters. Read More

    Nitric oxide blocks the development of the human parasite .
    Proc Natl Acad Sci U S A 2017 09 5;114(38):10214-10219. Epub 2017 Sep 5.
    Center for Parasitic Organisms, State Key Laboratory of Biocontrol, Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, People's Republic of China;
    Human schistosomiasis, caused by species, is a major public health problem affecting more than 700 million people in 78 countries, with over 40 mammalian host reservoir species complicating the transmission ecosystem. The primary cause of morbidity is considered to be granulomas induced by fertilized eggs of schistosomes in the liver and intestines. Some host species, like rats (), are naturally intolerant to infection, and do not produce granulomas or pose a threat to transmission, while others, like mice and hamsters, are highly susceptible. Read More

    Assessment of schistosomiasis and soil-transmitted helminths prevalence in school-aged children and opportunities for integration of control in local health services in Kwilu Province, the Democratic Republic of the Congo.
    Trop Med Int Health 2017 11 14;22(11):1442-1450. Epub 2017 Sep 14.
    Department of Public Health, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.
    Objective: To determine the prevalence of schistosomiasis (SCH) and soil-transmitted helminths (STH) in the Democratic Republic of Congo, and to assess the capacity of the local health centres for diagnosis and treatment.

    Methods: Cross-sectional school-based survey in two health districts in the Province of Kwilu. We collected a stool and a urine sample for parasitological examination. Read More

    Metazoan parasites from odontocetes off New Zealand: new records.
    Parasitol Res 2017 Oct 10;116(10):2861-2868. Epub 2017 Aug 10.
    Department of Zoology, University of Otago, 340 Great King Street, PO Box 56, Dunedin, 9054, New Zealand.
    Information about the parasite fauna of spectacled porpoises and cetaceans from New Zealand waters in general is scarce. This study takes advantage of material archived in collections of the Otago Museum in Dunedin and Massey University in Auckland, sampled from cetacean species found stranded along the New Zealand coastline between 2007 and 2014. Parasites from seven species of cetaceans (spectacled porpoise, Phocoena dioptrica (n = 2 individuals examined); pygmy sperm whale (n = 1); long-finned pilot whale, Globicephala melas (n = 1); Risso's dolphin, Grampus griseus (n = 1); short-beaked common dolphin, Delphinus delphis (n = 7); striped dolphin, Stenella coeruleoalba (n = 3) and dusky dolphin, Lagenorhynchus obscurus (n = 2)) from the respiratory and gastro-intestinal tract, cranial sinus, liver, urogenital and mammary tract, fascia and blubber were investigated. Read More

    Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania.
    World J Surg Oncol 2017 Aug 2;15(1):146. Epub 2017 Aug 2.
    Department of General Surgery, Kilimanjaro Christian Medical Centre, P.O Box 3010, Moshi, Tanzania.
    Background: Colorectal cancer associated with chronic intestinal schistosomiasis has been linked with the chronic inflammation as a result of schistosomal ova deposition in the submucosal layer of the intestine. Among all species Schistosoma japonicum has been more linked to development of colorectal cancer as compared to Schistosoma mansoni due to absence of population-based studies to support the association. Despite the weak evidence, some cases have been reported associating S. Read More

    Distribution and current infection status of Biomphalaria straminea in Hong Kong.
    Parasit Vectors 2017 Jul 25;10(1):351. Epub 2017 Jul 25.
    School of Life Science, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, People's Republic of China.
    Background: Schistosomiasis, also generally known as snail fever, is a parasitic disease caused by trematode flatworms of the genus Schistosoma. In Hong Kong and mainland China, the freshwater snail Biomphalaria straminea has been introduced and has the potential to transmit intestinal schistosomiasis caused by S. mansoni, a parasite of man which has a wide distribution in Africa and parts of the New World, especially Brazil. Read More

    Tissue Lesions Due to Spirorchiid Eggs in a Loggerhead Turtle ( Caretta caretta Linnaeus 1758) from Brazil: First Report Outside of the United States.
    J Parasitol 2017 Dec 24;103(6):801-803. Epub 2017 Jul 24.
    Universidade Estadual do Norte Fluminense Darcy Ribeiro-UENF, Campos dos Goytacazes, Rio de Janeiro, 28013-602, Brazil.
    Spirorchiids (family Spirorchiidae Stunkard 1921) are a group of flukes that inhabit the circulatory system of turtles. Infection by members of the family Spirorchiidae involves egg deposition in the host bloodstream and accumulation in tissues, which cause inflammatory reactions and embolisms, leading or contributing to the death of the host. Reports of spirorchiid egg lesions in loggerhead turtles ( Caretta caretta Linnaeus, 1758) have only been reported from U. Read More

    : Metacercariae Encysted in sp. Snails Purchased from Phnom Penh, Cambodia.
    Korean J Parasitol 2017 Jun 30;55(3):341-345. Epub 2017 Jun 30.
    Institute of Parasitic Diseases, Korea Association of Health Promotion, Seoul 07653, Korea.
    The metacercariae of (Leiper, 1911) Mendheim, 1943 were discovered in sp. snails purchased from a market in Phnom Penh, Cambodia. They were isolated from the snails using the artificial digestion technique and were orally fed to 2 hamsters, 1 rat, and 2 mice to obtain the adult flukes. Read More

    A Case of Ectopic Peritoneal Paragonimiasis Mimicking Diverticulitis or Abdominal Abscess.
    Korean J Parasitol 2017 Jun 30;55(3):313-317. Epub 2017 Jun 30.
    Department of Infectious Diseases, Asan Medical Center, Seoul 05505, Korea.
    Paragonimiasis is a parasitic disease caused by species. The primary site of infection is the lung, and extrapulmonary involvement is also reported. When infected with , which is the dominant species in Korea, the central nervous system is frequently involved along with the liver, intestine, peritoneal cavity, retroperitoneum, and abdominal wall. Read More

    Antibody trapping: A novel mechanism of parasite immune evasion by the trematode Echinostoma caproni.
    PLoS Negl Trop Dis 2017 Jul 17;11(7):e0005773. Epub 2017 Jul 17.
    Departamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Burjassot, Valencia, Spain.
    Background: Helminth infections are among the most prevalent neglected tropical diseases, causing an enormous impact in global health and the socioeconomic growth of developing countries. In this context, the study of helminth biology, with emphasis on host-parasite interactions, appears as a promising approach for developing new tools to prevent and control these infections.

    Methods/principal Findings: The role that antibody responses have on helminth infections is still not well understood. Read More

    Genetic line comparisons and genetic parameters for endoparasite infections and test-day milk production traits.
    J Dairy Sci 2017 Sep 6;100(9):7330-7344. Epub 2017 Jul 6.
    Institute of Animal Breeding and Genetics, Justus-Liebig-University of Gießen, 35390 Gießen, Germany. Electronic address:
    Keeping dairy cows in grassland systems relies on detailed analyses of genetic resistance against endoparasite infections, including between- and within-breed genetic evaluations. The objectives of this study were (1) to compare different Black and White dairy cattle selection lines for endoparasite infections and (2) the estimation of genetic (co)variance components for endoparasite and test-day milk production traits within the Black and White cattle population. A total of 2,006 fecal samples were taken during 2 farm visits in summer and autumn 2015 from 1,166 cows kept in 17 small- and medium-scale organic and conventional German grassland farms. Read More

    Longitudinal survey on the distribution of Biomphalaria sudanica and B. choanomophala in Mwanza region, on the shores of Lake Victoria, Tanzania: implications for schistosomiasis transmission and control.
    Parasit Vectors 2017 Jun 28;10(1):316. Epub 2017 Jun 28.
    Department of Life Sciences, Natural History Museum, Cromwell Road, London, SW7 5BD, UK.
    Background: Schistosomiasis is hyper-endemic in the Lake Victoria basin; with intestinal schistosomiasis plaguing communities adjacent to the lake, where the intermediate host snails live. The two intermediate host species of Schistosoma mansoni in the Mwanza region are Biomphalaria sudanica, found on the banks of the lakes, and B. choanomphala, found in the lake itself. Read More

    High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, Madagascar.
    Parasit Vectors 2017 Jun 24;10(1):307. Epub 2017 Jun 24.
    Ministère de la Santé Publique, Antananarivo, Madagascar.
    Background: A school-based survey was undertaken to assess prevalence and infection intensity of schistosomiasis in school-aged children in the Marolambo District of Madagascar.

    Methods: School-aged children from six purposively selected schools were tested for Schistosoma haematobium by urine filtration and Schistosoma mansoni using circulating cathodic antigen (CCA) and Kato-Katz stool analysis. The investigators did not address soil-transmitted helminths (STH) in this study. Read More

    Epidemiology of intestinal helminthiasis among school children with emphasis on Schistosoma mansoni infection in Wolaita zone, Southern Ethiopia.
    BMC Public Health 2017 06 20;17(1):587. Epub 2017 Jun 20.
    Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
    Background: Intestinal helminth infections are major parasitic diseases causing public health problems in Ethiopia. Although the epidemiology of these infections are well documented in Ethiopia, new transmission foci for schistosomiasis are being reported in different parts of the country. The objective of this study was to assess the prevalence of Schistosoma mansoni and other intestinal helminth infections among school children and determine the endemicity of schistosomiasis in Wolaita Zone, southern Ethiopia. Read More

    LAMPhimerus: A novel LAMP assay for detecting Amphimerus sp. DNA in human stool samples.
    PLoS Negl Trop Dis 2017 Jun 19;11(6):e0005672. Epub 2017 Jun 19.
    Infectious and Tropical Diseases Research Group (e-INTRO), Biomedical Research Institute of Salamanca-Research Centre for Tropical Diseases at the University of Salamanca (IBSAL-CIETUS), Faculty of Pharmacy, University of Salamanca, Salamanca, Spain.
    Background: Amphimeriasis is a fish-borne disease caused by the liver fluke Amphimerus spp. that has recently been reported as endemic in the tropical Pacific side of Ecuador with a high prevalence in humans and domestic animals. The diagnosis is based on the stool examination to identify parasite eggs, but it lacks sensitivity. Read More

    First record of a rare transversotrematid cercaria larva (Trematoda: Digenea) from Rajasthan, India: focus on seasonal occurrence and host-specificity of diverse cercariae.
    J Parasit Dis 2017 Jun 15;41(2):496-502. Epub 2016 Sep 15.
    Parasitology and Toxicology Research Laboratory, Post Graduate Department of Zoology, Government Meera Girls College, Udaipur, Rajasthan 313001 India.
    During the survey of freshwater snail hosts and their digenean larval trematode parasites, a rare cercaria larva belonging to family Transversotrematidae and subclass Digenea (Trematoda) was recovered from the snail species inhabiting perennial Som river of Udaipur district, Rajasthan, India. More than 28 % mature specimens of these snails were found to be infected with transversotrematid cercaria larvae in the spring season. Body of this cercaria is large, bowl-shaped, biocellate, spinose, transparent and laterally extended having two pigmented eye spots, two hold fast organs extended from the junction of body and tail, large tail with two foliated furcal rami, and cyclocoel intestinal caeca. Read More

    Intraspecific variation in adult Uvitellina iraquensis Dronen, Ali & Al-Amura, 2013 (Cyclocoelidae: Haematotrephinae) from two collection sites of white-tailed lapwing, Vanellus leucurus (Lichtenstein) (Charadriiformes: Charadriidae), in Iraq.
    Zootaxa 2017 Mar 9;4242(1):1-33. Epub 2017 Mar 9.
    Laboratory of Parasitology, Department of Wildlife and Fisheries Sciences, Texas A&M University, 2258 TAMU, College Station, Texas 77843-2258; USA..
    A total of 19 white-tailed lapwing, Vanellus leucurus, were collected from Huwazah Marsh, north-eastern Basrah Province, Iraq from February to March and in October, 2011 (collection site #1) and 60 V. leucurus were collected from Al-Hammar Marshes, Thi-Qar Province, southern Iraq from July to November, 2012 (collection site #2), and examined for cyclocoelids. Nineteen Uvitellina iraquensis Dronen, Ali & Al-Amura, 2013 from site #1 and 17 specimens from site #2 were fixed with minimal compression for comparisons of morphological characteristics, measurements, morphometric percentages and morphometric ratios commonly used to distinguish species of cyclocoelids. Read More

    The importance of patient compliance in repeated rounds of mass drug administration (MDA) for the elimination of intestinal helminth transmission.
    Parasit Vectors 2017 Jun 12;10(1):291. Epub 2017 Jun 12.
    London Centre for Neglected Tropical Disease Research, Department of Infectious Disease Epidemiology, St Mary's Campus, Imperial College London, London, W2 1PG, UK.
    Background: Systematic non-compliance to chemotherapeutic treatment among a portion of the eligible population is thought to be a major obstacle to the elimination of helminth infections by mass drug administration (MDA). MDA for helminths is repeated at defined intervals such as yearly or every 2 years, as a consequence of the inability of the human host to develop fully protective immunity to reinfection. As such, how an individual complies to these repeated rounds of MDA can have a significant impact on parasite transmission. Read More

    Redescription of Austrodiplostomum compactum (Trematoda: Diplostomidae) from its Type Host and Locality in Venezuela, and of Austrodiplostomum mordax from Argentina.
    J Parasitol 2017 Oct 10;103(5):497-505. Epub 2017 Jun 10.
    Departamento de Biodiversidad y Biología Experimental, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, 1428 Buenos Aires, Argentina.
    Austrodiplostomum compactum from Nannopterum brasilianus, and its metacercaria from Geophagus sp. and Oreochromis mossambicus captured (1979) at its type locality, Valencia Lake, Venezuela, by the author, are redescribed. The adult is characterized by its large body size, and an oral sucker smaller than the pharynx. Read More

    Present Situation of Opisthorchiasis in Vientiane Capital, Lao Peoples' Democratic Republic.
    Nihon Eiseigaku Zasshi 2017 ;72(2):101-105
    Graduate School of Nursing and Faculty of Nursing, Hiroshima Bunka Gakuen University.
    Opisthorchiasis is the commonest liver disease caused by Opisthorchis viverrini in Thailand, Lao People's Democratic Republic (PDR) and Cambodia, which will be a major cause of future human cholangiocarcinoma in these regions. In this short review, we describe the epidemic aspects of this parasite infection and the outline of results of our recent surveys of the fluke in humans and its intermediate hosts in Vientiane Capital, where information on the opisthorchiasis epidemic is insufficient. We examined the stool from a total of 296 persons living in the Phailom village (population, 1545, 1999) from 2011 to 2012. Read More

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