1,737 results match your criteria Interphalangeal Joint Arthritis

Application of Automated Hand Ultrasound Scanning and a Simplified Three-Joint Scoring System for Assessment of Rheumatoid Arthritis Activity.

Ultrasound Med Biol 2021 Jul 24. Epub 2021 Jul 24.

Department of Rheumatology and Immunology, Second Affiliated Hospital of Harbin Medical University, Harbin, China. Electronic address:

Ultrasound can be used to objectively diagnose and evaluate disease activity in patients with rheumatoid arthritis (RA). We aimed to determine the value of a new automated hand ultrasound (AHUS) scanning device and a simplified 3-joint ultrasound scoring system (US3) in detecting synovitis in RA. We compared AHUS and traditional ultrasound (US) scanning in detecting synovial hyperplasia (SH), joint effusion, bone erosion and power Doppler (PD) synovitis in 49 patients. Read More

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Multicentric Osteolysis, Nodulosis, and Arthropathy in two unrelated children with matrix metalloproteinase 2 variants: Genetic-skeletal correlations.

Bone Rep 2021 Dec 10;15:101106. Epub 2021 Jul 10.

Division of Pediatric Orthopaedics, Department of Orthopaedic Surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Multicentric Osteolysis, Nodulosis, and Arthropathy (MONA) syndrome is a rare genetic skeletal dysplasia. Its diagnosis can be deceptively similar to childhood-onset genetic skeletal dysplasias and juvenile idiopathic arthritis. We aimed to report the syndrome's clinical and radiologic features with emphasis on skeletal manifestations. Read More

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December 2021

One-stage Distal Interphalangeal Joint Fusion With External Fixator for the Treatment of Septic Joint Arthritis.

Tech Hand Up Extrem Surg 2021 Jul 19. Epub 2021 Jul 19.

Hand Surgery Unit, Department of Orthopedics Infectious Diseases Unit, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain.

Septic joint arthritis in the small joints of the hand can be caused by penetrating trauma, ruptured ganglion cysts, or open joint dislocations, among others. The use of external fixation for the treatment of this condition has been reported in the past as a means of temporary joint distraction, or for secondary fusion procedures. In the present article, the authors describe a surgical technique involving the use of a low-cost external fixator for the primary arthrodesis of infected distal interphalangeal joints of the hand. Read More

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Distinct aberrations in cerebral pain processing differentiating fibromyalgia from rheumatoid arthritis patients.

Pain 2021 Jun 28. Epub 2021 Jun 28.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden Department of Neuroradiology, Karolinska University Hospital, Stockholm, Sweden Department of Clinical Sciences, Karolinska Institutet, Danderyd University Hospital, Stockholm, Sweden Department of Medicine, Rheumatology Unit, Center for Molecular Medicine (CMM), Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden Department of Surgical Sciences/Pain Research, Uppsala University, Uppsala, Sweden.

Abstract: The current study used functional magnetic resonance imaging (fMRI) to directly compare disease-relevant cerebral pain processing in well-characterized patient cohorts of fibromyalgia (FM, nociplastic pain) and rheumatoid arthritis (RA, nociceptive pain). Secondary aims were to identify pain-related cerebral alterations related to the severity of clinical symptoms such as pain intensity, depression and anxiety. Twenty-six FM (without RA-comorbidity) and 31 RA (without FM-comorbidity) patients underwent fMRI while stimulated with subjectively calibrated painful pressures corresponding to a pain sensation of 50 mm on a 100 mm VAS scale. Read More

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Comparison of Ultrasonography and X-Rays for the Diagnosis of Synovitis and Bony Erosions in Small Joints of Hands in Early Rheumatoid Arthritis: a Prospective Study.

Maedica (Bucur) 2021 Mar;16(1):22-28

Department of Hospital Administration, PGIMER Chandigarh; PGIMER Satellite Centre, Sangrur, Punjab, India.

Rheumatoid arthritis (RA) is the most common inflammatory joint disease. Many studies have shown that erosions and synovitis can be picked up at an early stage on ultrasonography (US) when X-rays appear normal. Ultrasonography exams in inflammatory arthritis helps in determining objective evidence of inflammatory arthritis- synovitis, erosions, effusions and also help in monitoring therapy in established RA patients. Read More

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Hand Erosive Osteoarthritis and Distal Interphalangeal Involvement in Psoriatic Arthritis: The Place of Conservative Therapy.

J Clin Med 2021 Jun 15;10(12). Epub 2021 Jun 15.

Rehabilitation Department, IRCCS Sacro Cuore Don Calabria, 37024 Negrar, Italy.

Hand erosive osteoarthritis (HEOA) and Psoriatic Arthritis (PsA) with DIP involvement are common diseases affecting the hand. Both of them evolve with a progressive limitation in grip due to limited range of motion of the affected joints and stenosing tenosynovitis. Pharmacological options currently available (corticosteroids and clodronate or Idrossicloroquine) for the treatment of EHOA are mostly symptomatic and currently there are no effective drugs able to modify the course of the disease. Read More

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Adolescent-onset anti-MDA5 antibody-positive juvenile dermatomyositis with rapidly progressive interstitial lung disease and spontaneous pneumomediastinum: a case report and literature review.

Pediatr Rheumatol Online J 2021 Jun 30;19(1):103. Epub 2021 Jun 30.

Department of Paediatrics and Adolescent Medicine, Tuen Mun Hospital, Tuen Mun, Hong Kong SAR.

Background: Dermatomyositis with positive anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody has a distinct phenotype associated with small hand joint arthritis, mucocutaneous ulceration, palmar papules and less muscle involvement. It is also associated with increased risk of rapidly progressive interstitial lung disease (RP-ILD) and has a high mortality rate in adults. There is evidence that cases complicated with spontaneous pneumomediastinum (PNM) have an increase in mortality. Read More

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Magnetic Resonance Imaging evidence of Inflammation at Interphalangeal joint of Thumb - A distinct entity in psoriatic arthritis.

Int J Rheum Dis 2021 Jun 28. Epub 2021 Jun 28.

Department of Clinical Immunology & Rheumatology, Christian Medical College, Vellore, India.

Background: This study aimed to compare inflammation at the interphalangeal (IP) joint of thumb in patients with psoriatic arthritis (PsA), rheumatoid arthritis (RA), undifferentiated inflammatory arthritis (UIA), and in psoriasis patients without clinical arthritis (PsO) using low-field magnetic resonance imaging (MRI).

Methods: Age-matched and disease duration-matched patients with inflammatory arthritis (RA, PsA, and UIA) and psoriasis patients without clinical arthritis (PsO), who had undergone MRI of hands were included in this study. The presence or absence of MRI inflammatory lesions including synovitis, tenosynovitis, and bone marrow edema was assessed by three independent readers. Read More

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Chikungunya Fever: Comparison Study of Synovitis and Tenosynovitis of the Hands and Wrists Using Physical Examination, Ultrasound and MRI Findings.

J Ultrasound Med 2021 Jun 25. Epub 2021 Jun 25.

Department of Radiology, Rio de Janeiro State University, Rio de Janeiro, Brazil.

Objectives: To compare musculoskeletal changes on a physical examination (PE), ultrasound (US) and magnetic resonance imaging (MRI) of the hands and wrists of patients with Chikungunya fever (CF).

Methods: The sample consisted of 30 patients in the chronic phase of CF. The sites analyzed were the interphalangeal (IP), metacarpophalangeal (MCP) and wrist/mediocarpal (WMC) joints and periarticular soft tissue. Read More

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Ultrasonography of Inflammatory and Structural Lesions in Hand Osteoarthritis: An OMERACT Agreement and Reliability Study.

Arthritis Care Res (Hoboken) 2021 Jun 16. Epub 2021 Jun 16.

The Parker Institute, Copenhagen University Hospital Bispebjerg-Frederiksberg, Frederiksberg, Denmark.

Objective: To standardize and assess the reliability of ultrasonographic assessment of inflammatory and structural lesions in patients with hand osteoarthritis (OA).

Methods: The Outcome Measures in Rheumatology (OMERACT) Ultrasound Working Group selected synovial hypertrophy (SH), joint effusion (JE), and power Doppler (PD) signals as the main inflammatory lesions in hand OA, and suggested osteophytes in the scapho-trapezio-trapezoid (STT) and cartilage defects in the proximal interphalangeal (PIP) joints as novel additions to previous structural scoring systems. A complementary imaging atlas provided detailed examples of the scores. Read More

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Leprosy-Related Chronic Arthritis with an Abundance of in the Synovial Fluid: A Rare Case.

Int Med Case Rep J 2021 3;14:371-376. Epub 2021 Jun 3.

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Hasan Sadikin General Hospital, Bandung, West Java, 40161, Indonesia.

Bone and joint involvements are the most common manifestation in leprosy, after cutaneous and neurological manifestations, yet are underdiagnosed and rarely reported. We report a case of lepromatous leprosy in a 41-year-old male with bone and joint changes. Physical examination revealed a leonine face, madarosis, hypesthetic hypopigmented macules on the back, and swelling of fingers and toes. Read More

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Gastric Adenocarcinoma Presenting as a Rheumatoid Factor and Anti-cyclic Citrullinated Protein Antibody-Positive Polyarthritis: A Case Report and Review of Literature.

Front Med (Lausanne) 2021 24;8:627004. Epub 2021 May 24.

Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Centre, Lisbon, Portugal.

A 64-year-old male presented with a 6-month history of symmetric polyarthritis involving proximal interphalangeal joints and metacarpophalangeal joints of the hands, wrists, and ankles. Associated symptoms included vomiting, progressive fatigue, and weight loss. Laboratory results showed microcytic anemia, leukocytosis, thrombocytosis, elevated C-reactive protein and erythrocyte sedimentation rate, and rheumatoid factor (RF) and anti-cyclic citrullinated protein (ACPA) antibody positivity. Read More

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Hemi-hamate Arthroplasty for Base of Middle Phalanx Fracture: A Systematic Review.

Hand (N Y) 2021 Jun 8:15589447211014623. Epub 2021 Jun 8.

Australian Research Collaboration on the Hand, Mudgeeraba, QLD, Australia.

Intra-articular fracture dislocations of the base of the middle phalanx are complex and debilitating injuries that present a management conundrum when nonreconstructable. Hemi-hamate arthroplasty (HHA) is a treatment modality of particular use in the setting of highly comminuted fractures. This systematic review aims to summarize the reported outcomes of HHA in this context. Read More

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Ultrasound findings of finger, wrist and knee joints in Mucopolysaccharidosis Type I.

Mol Genet Metab 2021 Jul 1;133(3):289-296. Epub 2021 Jun 1.

Ospedale Provinciale Madonna del Soccorso, Department of Internal Medicine, San Benedetto del Tronto, Marche, Italy.

Introduction: Musculoskeletal findings in MPS can progress after enzyme replacement. Our aim was to examine synovial recesses, tendons, retinacula and pulleys using ultrasonography for structural and inflammatory changes.

Material And Methods: The wrist, metacarpophalangeal (MCP), proximal and distal interphalangeal (PIP and DIP) joints, the finger flexor tendons and the knee including entheses of quadriceps and patella tendons were assessed clinically. Read More

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Ultrasound Evaluation of the Effectiveness of the Use of Acitretin in the Treatment of Nail Psoriasis.

J Clin Med 2021 May 14;10(10). Epub 2021 May 14.

Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, School of Medicine, Collegium Medicum, University of Warmia and Mazury, 10-900 Olsztyn, Poland.

The study aimed to evaluate the effect of retinoid treatment on the morphological changes in the nail apparatus in patients with nail psoriasis.

Material And Methods: 41 patients aged 32 to 64 with nail psoriasis, without clinical signs of psoriatic arthritis, started on acitretin 0.6 to 0. Read More

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Septic Arthritis of the Proximal Interphalangeal Joint After Rattlesnake Bite.

J Hand Surg Am 2021 May 25. Epub 2021 May 25.

Brooke Army Medical Center, Department of Orthopaedic Surgery, Fort Sam Houston, TX.

Snake bites are an uncommon injury requiring intervention by hand surgeons. While counteracting the effects of snake venom is the initial and urgent concern following a bite, infection caused by retention of a foreign body can present in a delayed fashion and may lead to increased morbidity. Standard radiographs of the injury should be carefully examined for foreign bodies, noting that retained snake teeth are somewhat radiolucent due to less mineralization as compared to bone and can be difficult to visualize. Read More

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Metacarpophalangeal impairment in hand osteoarthritis is not rare and is associated with mechanical factors: Results from the DIGICOD hand osteoarthritis cohort.

Arthritis Care Res (Hoboken) 2021 May 10. Epub 2021 May 10.

Sorbonne University, Department of Rheumatology, Saint-Antoine Hospital, CRSA Inserm UMRS_938, Paris, 75012, France.

Objective: To determine the prevalence, distribution and characteristics associated with radiographic metacarpophalangeal (MCP) osteoarthritis (OA).

Methods: This is a cross-sectional study of baseline data from the DIGItal Cohort Osteoarthritis Design, a French monocentric cohort including patients with symptomatic hand OA (HOA). We evaluated the prevalence of radiographic MCP OA defined as ≥2 MCP joints with a Kellgren and Lawrence score ≥2. Read More

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Rare presentation of bilateral thumb psoriatic arthritis treated with arthrodesis: a case report.

AME Case Rep 2021 25;5:18. Epub 2021 Apr 25.

Department of Orthopaedic Surgery, Georgetown University School of Medicine, Washington, DC, USA.

Psoriatic arthritis (PsA) is a seronegative inflammatory arthritis that occurs concomitantly with cutaneous manifestations and tendinous pathology that affects up to 1% of the general population. While the majority of cases are mild, nearly 20% of PsA patients will progress to severe disease manifesting as debilitating polyarticular inflammation and joint destruction. PsA is most commonly asymmetric and bilateral severe disease involving the same joints in each hand has rarely been reported in the literature. Read More

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Early psoriatic arthritis in Japan: Post-hoc analyses from a survey by the Japanese Society of Psoriasis Research.

J Dermatol 2021 Jun 25;48(6):902-906. Epub 2021 Apr 25.

Department of Dermatology, Kinki University Faculty of Medicine, Osaka, Japan.

To determine the characteristics of the early phase of psoriatic arthritis (PsA), we conducted a subanalysis of a retrospective survey of Japanese patients. In this study, we enrolled patients with early onset within either 2 years or 1 year from onset among the 1282 patients with PsA that had previously been reported. Among the total reported PsA patients, 304 (23. Read More

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Correction to: Risk factors for the progression of finger interphalangeal joint osteoarthritis: a systematic review.

Rheumatol Int 2021 Jul;41(7):1373-1374

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Centre for Sport, Exercise and Osteoarthritis Research Versus Arthritis, University of Oxford, Oxford, UK.

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Development and reliability of a novel ultrasonographic joint-specific scoring system for synovitis with reference atlas for patients with juvenile idiopathic arthritis.

RMD Open 2021 04;7(2)

Department of Rheumatology, Oslo University Hospital, Oslo, Norway.

Objective: To develop an ultrasonographic image acquisition protocol and a joint-specific scoring system for synovitis with reference atlas in patients with juvenile idiopathic arthritis (JIA) and to assess the reliability of the system.

Methods: Seven rheumatologists with extensive ultrasound experience developed a scanning protocol and a semiquantitative joint-specific scoring system for B-mode (BM) synovitis for the elbow, wrist, metacarpophalangeal 2-3, proximal interphalangeal 2-3, hip, knee, ankle and metatarsophalangeal 2-3 joints. An ultrasonographic reference atlas for BM synovitis, divided in four age groups (2-4, 5-8, 9-12, 13-18 years), and power Doppler (PD) activity was then developed. Read More

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Knuckle pads mimic early psoriatic arthritis.

Reumatismo 2021 Apr 19;73(1):67-69. Epub 2021 Apr 19.

Department of Medical and Biological Science, Rheumatology Clinic, University of Udine.

Knuckle pads or Garrod's nodes are a rare, non-inflammatory condition. They consist of benign, well-circumscribed fibro-adipose tissue over the small joints of hands and feet. Knuckle pads may be under-diagnosed and mistaken for early arthritis. Read More

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Comparison of interfragmentary pinning versus the extension block technique for acute Doyle type 4c mallet finger.

Hand Surg Rehabil 2021 Apr 14. Epub 2021 Apr 14.

Department of Orthopaedics and Traumatology, Gaziosmanpasa University Tokat, Mah. Muhittin Fisunoğlu Cad. Ali Şevki Erek Yerleşkesi, Merkez/Tokat, Turkey.

The aim of this study was to compare the closed reduction interfragmentary pinning method (IPM) with the extension block technique (EBT) for bony mallet finger. Patients who underwent mallet finger operations were screened retrospectively for the following inclusion criteria: Doyle type 4c, age between 18 and 75 years, less than 4 weeks to surgery, and more than 1 year of follow-up time. Group I underwent a closed reduction IPM, and group II underwent the EBT. Read More

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Erosive Hand Osteoarthritis: Incidence and Predictive Characteristics among Participants in the Osteoarthritis Initiative.

Arthritis Rheumatol 2021 Apr 12. Epub 2021 Apr 12.

Care New England Medical Group/Primary Care and Specialty Services, Pawtucket, RI, USA.

Objective: To evaluate age, sex, race, osteoarthritis severity, metabolic factors, and bone health as risk factors for incident erosive hand osteoarthritis (EHOA) at baseline and over 48-month period.

Methods: This study was a longitudinal cohort design including participants from the Osteoarthritis Initiative with complete hand radiographs from baseline and 48-month visits who were eligible at baseline for incident EHOA. Individuals were classified as having EHOA if they had Kellgren-Lawrence (KL) grade≥2 in at least one interphalangeal joint on two different fingers and central erosion in at least one joint. Read More

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Unusual Subacute Interphalangeal Tophaceous Gouty Arthritis.

Cureus 2021 Mar 6;13(3):e13732. Epub 2021 Mar 6.

Rheumatology, Jersey Shore University Medical Center, Neptune, USA.

Gout is an arthritic syndrome that causes extensive joint damage and discomfort. It is due to an elevated uric acid level in the blood which deposits in the joints. This causes an inflammatory response and joint damage. Read More

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More than meets the naked eye: an unusual psoriatic arthritis mimicry and the important role of dermoscopic examination.

BMC Rheumatol 2021 Apr 12;5(1):10. Epub 2021 Apr 12.

School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, 16150, Kota Bharu, Kelantan, Malaysia.

Background: Psoriatic arthritis (PsA) can manifest in various forms. This includes mimicry of other diseases. We describe an unusual mimicry of PsA. Read More

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Psoriatic onycho-pachydermo periostitis (POPP): a case report treated successfully with IL-17 blockade and a literature review on characteristics, pathogenesis, and treatment.

Clin Rheumatol 2021 Apr 8. Epub 2021 Apr 8.

Department of Rheumatology, 424 General Army Hospital, Ring Road N. Efkarpias, 564 03, Thessaloniki, Greece.

Psoriatic onycho-pachydermo periostitis (POPP) is characterized by psoriatic onychodystrophy, connective tissue thickening, and periostitis of the distal phalanges (DPs), producing a drumstick-like deformity. Our aim was to present the first case of POPP treated successfully with an IL-17 inhibitor, perform a literature review of its characteristics and treatment, and explore the possible pathogenesis. We conducted a systematic review of previously presented POPP cases. Read More

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Focal Synovial Inflammation Versus Enthesitis Theory in Distal Psoriatic Arthritis: A Pioneer Histopathologic Study.

Am J Dermatopathol 2021 Mar 30. Epub 2021 Mar 30.

Laboratoire Central d'Anatomie Pathologique, Hôpital L. Pasteur, University of Nice, Nice, France; Nail's Dermatology Consultations, Cannes, France.

Abstract: The aim of this analysis was to re-examine the classical concept of distal interphalangeal joint (DIP) psoriatic arthritis (PsA) as an entheseal-driven disease. Two cadaveric fingers with severe psoriatic arthritis were analyzed. Our results demonstrate that inflammation of DIP PsA is multifocal without interconnection between entheses and articular cartilage of the DIP. Read More

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[Atypical arthritis of the hands : Collagenosis-part 2].

Matthias Bollow

Radiologe 2021 May 1;61(5):470-482. Epub 2021 Apr 1.

Klinik für diagnostische und interventionelle Radiologie, Augusta-Kranken-Anstalt Bochum, Bergstraße 26, 44791, Bochum, Deutschland.

Background: Progressive systemic scleroderma (PSS) and mixed connective tissue disease (MCTD) represent vasculitic autoimmune diseases from the group of collagenoses with manifestations in various organ systems such as the skin, the internal organs and the joints.

Objective: To present the atypical arthritis patterns of the hands in PSS and MCTD that differ from those in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) in the context of clinical and serologic findings and in consideration of the classification of PSS and MCTD.

Materials And Methods: Narrative review based on the current literature on the subject from the radiological and rheumatological point of view. Read More

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Therapeutic Potential of Digital Nerve Block in Rheumatoid Arthritis Patients: A Clinical and Sonographic Prospective Study.

Clin J Pain 2021 06;37(6):413-420

Department of Rheumatology and Rehabilitation, Sohag University Hospital, Sohag.

Background: This study attempted to test the effectiveness of digital nerve block (DNB) in active rheumatoid arthritis (RA) joints with respect to local disease control.

Methods: The study included 83 RA patients aged 18 years or above and diagnosed, after American College of Rheumatology/European League Against Rheumatism criteria 2010, with bilateral proximal interphalangeal (PIP) arthritis. PIPs were examined by European League Against Rheumatism-outcome measures in rheumatoid arthritis clinical trials scoring system at 0, 2, and 8 weeks. Read More

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