496,491 results match your criteria International journal of surgery London England[Journal]


[Study on the relationship between age-related hearing loss and cognitive impairment].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Feb;54(2):110-115

Department of Otorhinolaryngology, Peking University People's Hospital, Beijing 100044, China.

To investigate the correlation between age-related hearing loss and cognitive impairment. 201 elderly patients, who were admitted to the Department of Otorhinolaryngology of Peking University People's Hospital from March 1, 2017 to March 31, 2017, were evaluated with hearing screening and the Montreal Cognitive Assessment Scale. Among them, 101 were female and 100 were male, aged 60-90 years old. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2019.02.003DOI Listing
February 2019

[Epithelial Dystrophies of the Cornea].

Klin Monbl Augenheilkd 2019 Feb 18. Epub 2019 Feb 18.

In 2015, the first revision of the international classification of corneal dystrophies (IC3D) has been published. According to this latest version of the IC3D the dystrophies of the cornea are divided into · epithelial and subepithelial dystrophies,. · epithelial-stromal TGFBI dystrophies,. Read More

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http://dx.doi.org/10.1055/a-0849-0228DOI Listing
February 2019

The Cost of Hypoglycemia Associated With Type 2 Diabetes Mellitus in Taiwan.

Value Health Reg Issues 2019 Feb 15;18:84-90. Epub 2019 Feb 15.

Lilly Diabetes, Eli Lilly and Co (Taiwan), Taipei, Taiwan.

Objectives: To quantify the incremental burden of patients with type 2 diabetes mellitus (T2DM) and a hypoglycemic event in Taiwan using the National Health Insurance Research Database.

Methods: Data from 2000 through 2013 with an index period of 2001 through 2012 from the National Health Insurance Research Database's 2-million-patient sample were used. Using a nested case-control study design, patients were indexed if they reported a diagnosis of T2DM during the index period. Read More

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http://dx.doi.org/10.1016/j.vhri.2019.01.002DOI Listing
February 2019

Obesity Kuznets curve: international evidence.

Public Health 2019 Feb 15;169:26-35. Epub 2019 Feb 15.

Graduate School for International Development and Cooperation, Hiroshima University. 1-5-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8529, Japan. Electronic address:

Objectives: The obesity epidemic has prevailed worldwide and is currently recognized as a global pandemic disease. Given the argument that various socio-economic features contribute to substantial differences in obesity rates across countries, economic development can also be considered a crucial factor of such variation. This study examines the relationship between economic development and each of three weight-related health statuses (rates of overweight, obesity, and morbid obesity). Read More

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http://dx.doi.org/10.1016/j.puhe.2019.01.004DOI Listing
February 2019

Generation of human iPSCs from fetal prostate fibroblasts HPrF.

Stem Cell Res 2019 Feb 7;35:101405. Epub 2019 Feb 7.

Department of Cytokinetics, Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic. Electronic address:

Human induced pluripotent stem cell line was generated from commercially available primary human prostate fibroblasts HPrF derived from a fetus, aged 18-24 weeks of gestation. The fibroblast cell line was reprogrammed with Yamanaka factors (OCT4, SOX2, c-MYC, KLF4) using CytoTune™-iPS 2.0 Sendai Reprogramming Kit. Read More

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http://dx.doi.org/10.1016/j.scr.2019.101405DOI Listing
February 2019

Construction of Ag/AgCl-CN heterojunctions with enhanced photocatalytic activities for degrading contaminants in wastewater.

J Colloid Interface Sci 2019 Feb 1;543:25-33. Epub 2019 Feb 1.

State Environmental Protection Engineering Center for Pollution Treatment and Control in Textile Industry, College of Environmental Science and Engineering, Donghua University, Shanghai 201620, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai 200092, China. Electronic address:

The non-metallic organic polymer carbon nitride has attracted widespread attentions, but its photocatalytic performance is unsatisfactory due to high recombination of photoinduced carriers. To solve this issue, we report Ag/AgCl-decorated carbon nitride (CN) nanorod heterojunctions as efficient and stable photocatalyst. CN nanorods (diameter: ∼25 nm; lengths: 1-1. Read More

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http://dx.doi.org/10.1016/j.jcis.2019.01.133DOI Listing
February 2019

Addition-omission of zinc, copper, and boron nano and bulk oxide particles demonstrate element and size -specific response of soybean to micronutrients exposure.

Sci Total Environ 2019 Feb 11;665:606-616. Epub 2019 Feb 11.

The Connecticut Agricultural Experiment Station, 123 Huntington Street, New Haven, CT 06511, United States.

Plant response to microelements exposure can be modulated based on particle size. However, studies are lacking on the roles of particle size and specific microelements in mixed exposure systems designed for plant nutrition, rather than toxicology. Here, an addition-omission strategy was used to address particle-size and element-specific effects in soybean exposed to a mixture of nano and bulk scale oxide particles of Zn (2 mg Zn/kg), Cu (1 mg Cu/kg) and B (1 mg B/kg) in soil. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.02.142DOI Listing
February 2019

Parental age and the risk of childhood acute myeloid leukemia: results from the Childhood Leukemia International Consortium.

Cancer Epidemiol 2019 Feb 15;59:158-165. Epub 2019 Feb 15.

Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece; Clinical Epidemiology Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden. Electronic address:

Background: Parental age has been associated with several childhood cancers, albeit the evidence is still inconsistent.

Aim: To examine the associations of parental age at birth with acute myeloid leukemia (AML) among children aged 0-14 years using individual-level data from the Childhood Leukemia International Consortium (CLIC) and non-CLIC studies.

Material/methods: We analyzed data of 3182 incident AML cases and 8377 controls from 17 studies [seven registry-based case-control (RCC) studies and ten questionnaire-based case-control (QCC) studies]. Read More

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http://dx.doi.org/10.1016/j.canep.2019.01.022DOI Listing
February 2019
2.558 Impact Factor

Access to second-line drug susceptibility testing results among patients with Rifampicin resistant tuberculosis after introduction of the Hain Line Probe Assay in Southern provinces, Zimbabwe.

Int J Infect Dis 2019 Feb 15. Epub 2019 Feb 15.

International Union Against Tuberculosis and Lung Disease (The Union), Paris, France; London School of Hygiene and Tropical Medicine, London, UK.

Objectives: To determine the proportion of rifampicin-resistant tuberculosis (RR-TB) patients who accessed second-line drug susceptibility testing (SL-DST) results following introduction of the Hain technology in southern provinces, Zimbabwe.

Design: Cohort study using secondary data.

Results: Xpert MTB/RIF results were used to identify 133 RR-TB patients for this study. Read More

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http://dx.doi.org/10.1016/j.ijid.2019.02.007DOI Listing
February 2019

Strengthening laboratory surveillance of viral pathogens: Experiences and lessons learned building next-generation sequencing capacity in Ghana.

Int J Infect Dis 2019 Feb 15. Epub 2019 Feb 15.

Division of Viral Diseases, CDC, Atlanta, Georgia, 30329, USA.

Objectives: To demonstrate the feasibility of applying next-generation sequencing (NGS) in medium-resource reference laboratories in Africa to enhance global disease surveillance.

Methods: A training program was developed to support implementation of NGS at Noguchi Memorial Institute for Medical Research (NMIMR), University of Ghana. The program was divided into two training stages, first at the Centers for Disease Control and Prevention (CDC) in Atlanta, GA, followed by on-site training at NMIMR for a larger cohort of scientists. Read More

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http://dx.doi.org/10.1016/j.ijid.2019.02.008DOI Listing
February 2019

Nursing student attitudes to people labelled with 'mental illness' and consumer participation: A survey-based analysis of findings and psychometric properties.

Nurse Educ Today 2019 Feb 12;76:89-95. Epub 2019 Feb 12.

Department of Nursing, University of Iceland, Reykjavik, Iceland. Electronic address:

Background: Understanding student attitudes towards people diagnosed with mental illness is central to realising evidence-based nursing education and policy at an international level. Redressing stigmatised views can assist in preparing nursing students to work in mental health settings and support the active involvement of consumers in all aspects of mental health service delivery (known as: consumer participation) at individual and systemic levels. Accurate research on nursing student attitudes is dependent on the availability of valid and reliable measures. Read More

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http://dx.doi.org/10.1016/j.nedt.2019.02.003DOI Listing
February 2019

Development and psychometric properties of the assessment questionnaire for the process of the tutorial action plan.

Nurse Educ Today 2019 Feb 13;76:109-117. Epub 2019 Feb 13.

Campus Docent Sant Joan de Déu-Fundació Privada, School of Nursing, University of Barcelona, Barcelona, Spain; Research Group GIES (Grupo de investigación en Enfermería, Educación y Sociedad), Spain; Research Committee of the Campus Docent SJD, Spain; Neonatal and Pediatric Hospital Pedagogy Research Group, Spain.

Background: Internationally, most countries recognize the right of the student to receive assistance from teachers and tutors. The Tutorial Action Plan is a teaching tool that aims to promote academic, personal, and professional development in students. It is important to monitor this process of tutoring to be able to provide appropriate guidance to nursing students throughout their education. Read More

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http://dx.doi.org/10.1016/j.nedt.2019.02.002DOI Listing
February 2019

Reliability of supraspinal correlates to lower urinary tract stimulation in healthy participants - A fMRI study.

Neuroimage 2019 Feb 15. Epub 2019 Feb 15.

Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland. Electronic address:

Previous functional neuroimaging studies provided evidence for a specific supraspinal network involved in lower urinary tract (LUT) control. However, data on the reliability of blood oxygenation level-dependent (BOLD) signal changes during LUT task-related functional magnetic resonance imaging (fMRI) across separate measurements are lacking. Proof of the latter is crucial to evaluate whether fMRI can be used to assess supraspinal responses to LUT treatments. Read More

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http://dx.doi.org/10.1016/j.neuroimage.2019.02.031DOI Listing
February 2019

The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity.

J Allergy Clin Immunol Pract 2019 Feb 15. Epub 2019 Feb 15.

Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany; Center for Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Germany. Electronic address:

Patient registries are instrumental for clinical research in rare diseases. They help to achieve a sufficient sample size for epidemiological and clinical research and to assess the feasibility of clinical trials. The European Society for Immunodeficiencies (ESID) registry currently comprises information on >25,000 patients with inborn errors of immunity (IEI). Read More

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http://dx.doi.org/10.1016/j.jaip.2019.02.004DOI Listing
February 2019

Hyperglycemia is associated with psoriatic inflammation in both humans and mice.

J Invest Dermatol 2019 Feb 15. Epub 2019 Feb 15.

Department of Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan. Electronic address:

Chronic low-grade inflammation can cause several metabolic syndromes. Patients with psoriasis, a chronic immunological skin inflammation, often develop diabetes. However, it is not clear to date how psoriasis leads to, or is correlated with, glucose intolerance. Read More

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http://dx.doi.org/10.1016/j.jid.2019.01.029DOI Listing
February 2019

Microplitis bicoloratus bracovirus modulates innate immune suppression through the eIF4E-eIF4A axis in Spodoptera litura.

Dev Comp Immunol 2019 Feb 15. Epub 2019 Feb 15.

School of Life Sciences, Yunnan University, Kunming, 650500, PR China; Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, 650500, PR China; Biocontrol Engineering Research Centre of Crop Disease & Pest in Yunnan Province, Kunming, 650500, PR China; Key Laboratory for Biochemistry and Molecular Biology and School of Life Sciences, Yunnan University, Kunming, 650500, PR China; Animal Genetic Diversity and Evolution of High Education in Yunnan Province, School of Life Sciences, Yunnan University, Kunming, 650500, PR China. Electronic address:

Eukaryotic initiation factor 4E (eIF4E) is regulated during the innate immune response. However, its translational regulation under innate immune suppression remains largely unexplored. Microplitis bicoloratus bracovirus (MbBV), a symbiotic virus harbored by the parasitoid wasp, Microplitis bicoloratus, suppresses innate immunity in parasitized Spodoptera litura. Read More

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http://dx.doi.org/10.1016/j.dci.2019.02.010DOI Listing
February 2019

Developability assessment of physicochemical properties and stability profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 envelope glycoprotein trimers as candidate vaccine antigens.

J Pharm Sci 2019 Feb 15. Epub 2019 Feb 15.

International AIDS Vaccine Initiative, New York, NY 10004 USA. Electronic address:

The induction of broadly neutralizing antibodies (bNAb) is a major goal in the development of an effective vaccine against HIV-1. A soluble, trimeric, germline (gI) bNAb-targeting variant of the HIV-1 envelope glycoprotein (termed BG505 SOSIP.v4. Read More

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http://dx.doi.org/10.1016/j.xphs.2019.01.033DOI Listing
February 2019

The Global Paradigm Shift in Screening for Colorectal Cancer.

Gastroenterology 2019 Feb 16. Epub 2019 Feb 16.

Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1053/j.gastro.2019.02.006DOI Listing
February 2019
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Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia.

FASEB J 2019 Feb 18:fj201802058RR. Epub 2019 Feb 18.

State Key Laboratory of Maternal and Fetal Medicine of Chongqing Municipality, Chongqing Medical University, Chongqing, China.

Successful pregnancy requires normal placentation, which largely depends on the tight regulation of proliferation, invasion, and migration of trophoblast cells. Abnormal functioning of trophoblast cells may cause failure of uterine spiral artery remodeling, which may be related to pregnancy-related disorders, such as preeclampsia. Here, we reported that an actin-binding protein, α-actinin (ACTN)4, was dysregulated in placentas from early onset preeclampsia. Read More

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http://dx.doi.org/10.1096/fj.201802058RRDOI Listing
February 2019

Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale-2 in Parkinson's disease.

Mov Disord 2019 Feb 10;34(2):285-291. Epub 2018 Dec 10.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA.

Background: Clinicians and researchers commonly use global cognitive assessments to screen for impairment. Currently there are no published studies directly comparing the sensitivity and specificity of the Montreal Cognitive Assessment and Mattis Dementia Rating Scale-2 in PD. The objective of this study was to identify the relative sensitivity and specificity of the Montreal Cognitive Assessment and Mattis Dementia Rating Scale-2 in PD. Read More

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http://dx.doi.org/10.1002/mds.27575DOI Listing
February 2019

A proposal for sectorial organizing and quality standards in therapeutic apheresis: The therapeutic apheresis unit (TAU) standards.

J Clin Apher 2019 Feb 18. Epub 2019 Feb 18.

Transfusion Medicine and Stem Cell Unit, San Camillo Forlanini Hospital, Rome, Italy.

Therapeutic apheresis (TA) includes a wide range of therapeutic procedures based on the separation of blood components and the collection of cells with therapeutic activity or the removal of unwanted plasma or cellular components involved in the etiology of various hematologic, renal, neurological, and medical diseases. The complexity of these interventions requires an organizing model to assure a proper clinical environment, technology, quality requirements, and personnel as well as an active system for outcome monitoring for safety and efficacy. Finally, a structured organizing model may favor the efficiency of the TA unit and economic affordability. Read More

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http://dx.doi.org/10.1002/jca.21689DOI Listing
February 2019

Sequencing of anthracyclines and taxanes in neoadjuvant and adjuvant therapy for early breast cancer.

Cochrane Database Syst Rev 2019 Feb 18;2:CD012873. Epub 2019 Feb 18.

Medical Oncology Department, Concord Repatriation General Hospital, Concord, New South Wales, Australia, 2139.

Background: Anthracyclines and taxanes are chemotherapeutic agents widely used in a sequential regimen in the adjuvant and neoadjuvant treatment of early breast cancer to reduce the risk of cancer recurrence. Standard practice is to administer anthracycline-based chemotherapy followed by a taxane. Anthracyclines tend to be administered first as they were established before taxanes for treatment of early breast cancer. Read More

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http://dx.doi.org/10.1002/14651858.CD012873.pub2DOI Listing
February 2019
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A proposal for updating the staging of endometrial cancer.

Int J Gynaecol Obstet 2019 Feb 18. Epub 2019 Feb 18.

Department of Pathology, Autonomous University of Barcelona, Barcelona, Spain.

Since the last update of the International Federation of Gynecology and Obstetrics (FIGO) staging for corpus uteri cancer in 2009, a number of new insights into pathology, molecular genetics, and prognostic factors that justify a revision have been made. We recommend incorporation of histotype and grade along with depth of myometrial invasion to define stage I endometrial cancer, a change from 3-tier grading to binary grading, and inclusion of lymph node status (negative versus not removed) in the definition of stage I disease. Elimination of cervical involvement to define stage II and inclusion of positive peritoneal cytology to upstage otherwise stage I cancers to stage IIA is also recommended. Read More

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http://dx.doi.org/10.1002/ijgo.12789DOI Listing
February 2019

Outcomes following pancreatic surgery using three different thromboprophylaxis regimens.

Br J Surg 2019 Feb 18. Epub 2019 Feb 18.

Department of Surgery, Leiden University Medical Centre, Leiden, the Netherlands.

Background: Postpancreatectomy haemorrhage (PPH) and venous thromboembolism (VTE) are serious complications following pancreatic surgery. The aim was to assess the timing, occurrence and predictors of PPH and VTE.

Methods: Elective pancreatic resections undertaken in a single university hospital between November 2013 and September 2017 were assessed. Read More

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http://dx.doi.org/10.1002/bjs.11103DOI Listing
February 2019

Investigative practice into sudden death in epilepsy: A global survey.

Acta Neurol Scand 2019 Feb 18. Epub 2019 Feb 18.

Department of Intellectual Disability Neuropsychiatry, Cornwall Partnership NHS Foundation Trust, Truro, TR1 3QB, UK.

Objectives: Sudden death is a recognised consequence of epilepsy. Little is known about the practice of confirming the cause of sudden death from most nations. We sought to determine how often autopsy is undertaken, clinician confidence in cause of death, and identify the factors which may influence autopsy utilization. Read More

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http://dx.doi.org/10.1111/ane.13080DOI Listing
February 2019

Assessment of Screen Exposure in Young Children, 1997 to 2014.

JAMA Pediatr 2019 Feb 18. Epub 2019 Feb 18.

Department of Health Policy and Management, Robert Stempel College of Public Health and Social Work, Florida International University, Miami.

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http://dx.doi.org/10.1001/jamapediatrics.2018.5546DOI Listing
February 2019

Factors Associated With High-Quality Guidelines for the Pharmacologic Management of Chronic Diseases in Primary Care: A Systematic Review.

JAMA Intern Med 2019 Feb 18. Epub 2019 Feb 18.

Departamento de Ciências Farmacêuticas, Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, Diadema, São Paulo, Brazil.

Importance: As the rate of publication of new and sometimes conflicting medical research increases, clinicians rely heavily on clinical practice guidelines (CPGs) to inform practice. However, CPGs are of widely variable quality, and there are no existing objective measures to rate the quality of CPGs.

Objective: To systematically assess 421 CPGs for the management of common noncommunicable diseases in primary care using the validated Appraisal of Guidelines for Research and Evaluation Instrument, version II (AGREE-II) tool and elucidate the factors associated with quality of CPGs. Read More

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http://dx.doi.org/10.1001/jamainternmed.2018.7529DOI Listing
February 2019

Development and characterization of 20 polymorphic microsatellite markers for Epinephelus marginatus (Lowe, 1834) (Perciformes: Epinephelidae) using 454 pyrosequencing.

Genet Mol Biol 2019 Feb 14. Epub 2019 Feb 14.

Núcleo Integrado de Biotecnologia, Universidade de Mogi das Cruzes, Mogi das Cruzes, SP, Brazil.

The dusky grouper, Epinephelus marginatus, is a well-known and widespread marine fish assessed as endangered by the International Union for the Conservation of Nature. Analyzing the genetic diversity of this species is, therefore, of utmost importance and necessary for conservation purposes. Microsatellites are molecular tools with advantages that are ideal for population analyses. Read More

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http://dx.doi.org/10.1590/1678-4685-GMB-2018-0067DOI Listing
February 2019

The Alz-tau Biomarker for Alzheimer's Disease: Study in a Caucasian Population.

J Alzheimers Dis 2019 Feb 11. Epub 2019 Feb 11.

Laboratory of Neuroscience, International Center for Biomedicine (ICC) and Faculty of Sciences, University of Chile, Santiago, Chile.

The establishment of a molecular biomarker for early detection of Alzheimer's disease (AD) is critical for diagnosis and follow up of patients, and as a quantitative parameter in the evaluation of potential new drugs to control AD. A list of blood biomarkers has been reported but none has been validated for the Alzheimer's clinic. The changes in hyperphosphorylated tau and amyloid peptide in the cerebrospinal fluid is currently used as a tool in the clinics and for research purposes, but this method is highly invasive. Read More

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http://dx.doi.org/10.3233/JAD-180637DOI Listing
February 2019

Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases.

Elife 2019 Feb 18;8. Epub 2019 Feb 18.

Institute of Cellular Biochemistry, University Medical Center Goettingen, Goettingen, Germany.

Perturbations in mitochondrial function and homeostasis are pervasive in lysosomal storage diseases, but the underlying mechanisms remain unknown. Here, we report a transcriptional program that represses mitochondrial biogenesis and function in lysosomal storage diseases Niemann-Pick type C (NPC) and acid sphingomyelinase deficiency (ASM), in patient cells and mouse tissues. This mechanism is mediated by the transcription factors KLF2 and ETV1, which are both induced in NPC and ASM patient cells. Read More

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http://dx.doi.org/10.7554/eLife.39598DOI Listing
February 2019
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The name Bradyrhizobiaceae Garrity et al. 2006 contains Nitrobacter Winogradsky 1892 (Approved Lists 1980), the nomenclatural type of the family Nitrobacteraceae Buchanan 1917 (Approved Lists 1980), is illegitimate and proposals to alter the wording of Rule 54 of the International Code of Nomenclature of Prokaryotes to clarify the fact that the family name Bradyrhizobiaceae Garrity et al. 2006 is replaced by the family name Nitrobacteraceae Buchanan 1917 (Approved Lists 1980) the only correct name.

Authors:
B J Tindall

Int J Syst Evol Microbiol 2019 Feb 18. Epub 2019 Feb 18.

Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, Inhoffenstraße 7B, 38124 Braunschweig, Germany.

The new name at the rank of family Bradyrhizobiaceae Garrity et al. 2006 was created to include the genera Afipia Brenner et al. 1992, Agromonas Ohta and Hattori 1985, Blastobacter Zavarzin 1961 (Approved Lists 1980), Bosea Das et al. Read More

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http://dx.doi.org/10.1099/ijsem.0.003253DOI Listing
February 2019

Influence of Survivors' Entrapment Factors and Traffickers' Characteristics on Perceptions of Interpersonal Social Power During Exit.

Violence Against Women 2019 Feb 18:1077801219826742. Epub 2019 Feb 18.

2 University of Texas at Arlington, USA.

Typically examined in terms of understanding vulnerabilities to and the scope of human trafficking, not much is understood about interpersonal dynamics in human trafficking experiences. This article explores human trafficking victims' ( n = 31, female, international) perceptions of traffickers' interpersonal social power during the exiting phase of the trafficking experience. Findings from this study revealed that entrapment factors and shared common characteristics between victim and trafficker prior to trafficking influenced perceptions of interpersonal social power. Read More

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http://dx.doi.org/10.1177/1077801219826742DOI Listing
February 2019

Serum calcium levels at admission is associated with the outcomes in patients with hypertensive intracerebral hemorrhage.

Br J Neurosurg 2019 Feb 18:1-4. Epub 2019 Feb 18.

a The First Affiliated Hospital of Soochow University , Suzhou , China.

Background/objective: Hypertensive spontaneous intracerebral hemorrhages (ICH) cause significant morbidity and mortality. In this study, we aimed to investigate the association between calcium level at admission and outcome in hypertensive ICH patients.

Methods: 658 hypertensive ICH patients were enrolled from January 2012 to January 2016 in this retrospective study, and demographic, clinical, laboratory, radiographic, and outcome data were collected. Read More

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http://dx.doi.org/10.1080/02688697.2019.1571162DOI Listing
February 2019

Lung cancer family history and exposure to occupational/domestic coal combustion contribute to variations in clinicopathologic features and gene fusion patterns in non-small cell lung cancer.

Thorac Cancer 2019 Feb 18. Epub 2019 Feb 18.

Department of Thoracic Surgery I, The Third Affiliated Hospital of Kunming Medical University/Yunnan Cancer Hospital, Yunnan Cancer Center, The International Cooperation Key Laboratory of Regional Tumor in High Altitude Area, Kunming, China.

Background: Both genetic and environmental factors contribute to the development of cancer and its mutant spectrum. Lung cancer has familial aggregation. Lung cancer caused by non-tobacco factors has unique pathological and molecular characteristics. Read More

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http://dx.doi.org/10.1111/1759-7714.12987DOI Listing
February 2019

Transition experiences of newly graduated Filipino nurses in a resource-scarce rural health care setting: A qualitative study.

Nurs Forum 2019 Feb 18. Epub 2019 Feb 18.

Graduate School, Emilio Aguinaldo College, Manila, Philippines.

Problem: Without a doubt, the transition to a professional nursing role is a challenging and stressful experience for many new nurses, regardless of where they are employed; yet, no study has been conducted to comprehend in detail the transition experiences of newly graduated nurses employed in a resource-scarce rural health care setting.

Purpose: This study describes the transition experiences of newly graduated Filipino nurses during their initial clinical placement process.

Methods: A qualitative phenomenological approach using structured interviews with 15 newly graduated Filipino nurses were used along with the Coliazzi's methodological framework for data analysis. Read More

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http://dx.doi.org/10.1111/nuf.12330DOI Listing
February 2019

Incorporation of a rhodamine B conjugated polymer for nanoparticle trafficking both in vitro and in vivo.

Biomater Sci 2019 Feb 18. Epub 2019 Feb 18.

School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 510006, P. R. China. and Institutes for Life Sciences and School of Medicine, South China University of Technology, Guangzhou, Guangdong 510006, China. and Guangdong Key Laboratory of Nanomedicine, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China and Research Institute for Food Nutrition and Human Health, South China University of Technology, Guangzhou 510641, China and Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou 510005, China.

Polymeric nanoparticles as drug delivery systems have the potential to improve the therapeutic efficacy and reduce the toxicity of chemotherapeutic drugs by enhancing the drug selectivity in vivo. The efficacy is directly dependent on the polymeric nanoparticles' in vivo fate. Therefore, it is very important to develop a method to stably label the polymeric nanoparticles for detecting the in vivo fate. Read More

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http://xlink.rsc.org/?DOI=C9BM00032A
Publisher Site
http://dx.doi.org/10.1039/c9bm00032aDOI Listing
February 2019
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Photoinduced peeling of molecular crystals.

Chem Commun (Camb) 2019 Feb 18. Epub 2019 Feb 18.

Department of Chemistry, University of California, Riverside, 501 Big Springs Road, Riverside, CA 92521, USA.

Block-like microcrystals composed of cis-dimethyl-2(3-(anthracen-9-yl)allylidene)malonate are grown from aqueous surfactant solutions. A pulse of 405 nm light converts a fraction of molecules to the trans isomer, creating an amorphous mixed layer that peels off the parent crystal. This photoinduced delamination can be repeated multiple times on the same block. Read More

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http://dx.doi.org/10.1039/c8cc10051aDOI Listing
February 2019

Evidence for Hidden Involvement of N3-Protonated Guanine in RNA Structure and Function.

ACS Omega 2019 Jan 9;4(1):699-709. Epub 2019 Jan 9.

Center for Computational Natural Sciences and Bioinformatics (CCNSB), International Institute of Information Technology, Hyderabad (IIIT-H), Gachibowli, Hyderabad 500032, Telangana, India.

Charged nucleobases have been found to occur in several known RNA molecules and are considered essential for their structure and function. The mechanism of their involvement is however not yet fully understood. Revelation of the role of N7-protonated guanine, in modulating the geometry and stability of noncanonical base pairs formed through its unprotonated edges [Watson-Crick (WC) and sugar], has triggered the need to evaluate the feasibility of similar roles of other protonated nucleobases [Halder et al. Read More

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http://dx.doi.org/10.1021/acsomega.8b02908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372247PMC
January 2019

The development of Taiwan Fracture Liaison Service network.

Osteoporos Sarcopenia 2018 Jun 7;4(2):47-52. Epub 2018 Jun 7.

Superintendent Office, National Taiwan University Hospital Chu-Tung Branch, Hsinchu County, Taiwan.

Osteoporosis and its associated fragility fractures are becoming a severe burden in the healthcare system globally. In the Asian-Pacific (AP) region, the rapidly increasing in aging population is the main reason accounting for the burden. Moreover, the paucity of quality care for osteoporosis continues to be an ongoing challenge. Read More

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http://dx.doi.org/10.1016/j.afos.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362955PMC

Urban-Rural Disparities in Chronic Obstructive Pulmonary Disease Management and Access in Uganda.

Chronic Obstr Pulm Dis 2019 Jan 4;6(1):17-28. Epub 2019 Jan 4.

Department of Medicine and Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda.

Almost 90% of chronic obstructive pulmonary disease (COPD) deaths occur in low- and middle-income countries (LMICs), where there are large rural populations and access to health care for COPD is poor. The purpose of this study was to compare urban-rural provider experiences regarding systemic facilitators and barriers to COPD management and treatment access. We conducted a qualitative study using direct observations and in-depth semi-structured interviews with 16 and 10 health care providers in urban Kampala and rural Nakaseke, Uganda, respectively. Read More

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http://dx.doi.org/10.15326/jcopdf.6.1.2018.0143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373590PMC
January 2019

Severe Crohn's Disease Manifestations in a Child with Cystathionine β-Synthase Deficiency.

ACG Case Rep J 2018 5;5:e93. Epub 2018 Dec 5.

King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Inflammatory bowel diseases (IBDs) are idiopathic autoimmune diseases that are characterized by inflammation of both the small and large intestine. Although IBD is common in the general population, the pathophysiology remains ambiguous. Clear understanding of IBD pathophysiology would be a major step toward curative treatment in the future. Read More

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http://dx.doi.org/10.14309/crj.2018.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358571PMC
December 2018

European Respiratory Society International Congress, Paris, 2018: highlights from the Clinical Assembly.

ERJ Open Res 2019 Feb 11;5(1). Epub 2019 Feb 11.

Dept of Pneumology and Critical Care Medicine, Thoraxklinik, Heidelberg University Hospital, Heidelberg, Germany.

This article contains highlights and a selection of the scientific advances from the European Respiratory Society's Clinical Assembly (Assembly 1 and its five respective groups) that were presented at the 2018 European Respiratory Society International Congress in Paris, France. The most relevant topics from each of the groups will be discussed, covering a wide range of areas including clinical problems, rehabilitation and chronic care, thoracic imaging, interventional pulmonology, and general practice and primary care. The newest research, actual data and highlight sessions will be discussed. Read More

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http://dx.doi.org/10.1183/23120541.00176-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368995PMC
February 2019

Rapid detection of salmonellosis due to serovar Typhimurium in Peruvian commercially bred cavies, using indigenous wild bacteriophages.

Germs 2018 Dec 3;8(4):178-185. Epub 2018 Dec 3.

MD, PhD, Dr Med, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado Nº 430, San Martín de Porras, Lima 31, Lima, Perú.

Introduction: The salmonelloses are among the commonest, most widespread human zoonotic infections. They have generated international networks to attempt their control, since they cause a spectrum of ailments, ranging from inapparent carrier states to full-blown, severe, sometimes deadly diarrheal and systemic disease. Rapid diagnosis is needed for a number of reasons. Read More

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http://dx.doi.org/10.18683/germs.2018.1144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363402PMC
December 2018

Apremilast in Psoriasis and Beyond: Big Hopes on a Small Molecule.

Indian Dermatol Online J 2019 Jan-Feb;10(1):1-12

Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Apremilast, an orally administered small molecule inhibitor of phosphodiesterase 4 (PDE4), has been licensed by the US Food and Drug Administration for the management of active psoriatic arthritis (March 21, 2014) and moderate to severe plaque psoriasis (September 23, 2014). It has got approval from Drug Controller General of India for marketing in India in 2017. The drug has drawn much attention from the practising dermatologists for its commendable safety profile and prescription convenience. Read More

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http://dx.doi.org/10.4103/idoj.IDOJ_437_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362739PMC
February 2019

Scaling up isoniazid preventive therapy in Zimbabwe: has operational research influenced policy and practice?

Public Health Action 2018 Dec;8(4):218-224

International Union Against Tuberculosis and Lung Disease, Paris, France.

Following the operational research study conducted during the isoniazid preventive therapy (IPT) pilot phase in Zimbabwe, recommendations for improvement were adopted by the national antiretroviral therapy (ART) programme. To compare before (January 2013-June 2014) and after the recommendations (July 2014-December 2015), the extent of IPT scale-up and IPT completion rates, and after the recommendations the risk factors for IPT non-completion, in 530 ART clinics. Retrospective cohort study. Read More

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http://dx.doi.org/10.5588/pha.18.0051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361487PMC
December 2018

HIV, HBV and HCV in people who inject drugs and are placed on methadone maintenance therapy, Yangon, Myanmar.

Public Health Action 2018 Dec;8(4):202-210

National Drug Abuse Prevention and Control Programme, Ministry of Health and Sports, Nay Pyi Taw, Myanmar.

Two drug treatment centres (DTCs) for people who inject drugs (PWID) and are enrolled in methadone maintenance therapy (MMT), Yangon, Myanmar. To determine, in PWID enrolled for MMT from 2015 to 2017, 1) testing uptake and results for human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV); 2) risk factors for infection; and 3) retention in care and risk factors for loss to follow-up (LTFU). Cohort study using secondary data. Read More

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http://dx.doi.org/10.5588/pha.18.0050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361496PMC
December 2018

Tuberculosis retreatment outcomes and associated factors: a mixed-methods study from Puducherry, India.

Public Health Action 2018 Dec;8(4):187-193

Department of Community Medicine, Pondicherry Institute of Medical Science (PIMS), Puducherry, India.

Four Tuberculosis (TB) Units in the Union Territory of Puducherry in India. To identify factors associated with unfavourable outcomes among retreatment TB cases in Puducherry. The study had a mixed-methods design in which routinely reported TB data from retreatment TB cases registered during 2014 and 2015 were used for the quantitative part; the qualitative phase comprised interviews and focus group discussions with health care providers. Read More

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http://dx.doi.org/10.5588/pha.18.0038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361493PMC
December 2018

Sputum smear-positive, Xpert MTB/RIF-negative results: magnitude and treatment outcomes of patients in Myanmar.

Public Health Action 2018 Dec;8(4):181-186

National Tuberculosis Programme, Department of Public Health, Ministry of Health and Sports, Nay Pyi Taw, Myanmar.

Myanmar's National Tuberculosis Programme (NTP) uses the Xpert MTB/RIF assay to diagnose rifampicin (RMP) resistance in sputum smear-positive (Sm+) pulmonary tuberculosis (TB) patients. The Xpert test may occasionally yield negative results (Xpert-) for Mycobacterium tuberculosis complex, indicating a false-positive sputum smear result, false-negative Xpert result or infection with non-tuberculous mycobacteria (NTM). Patients with NTM may respond poorly to first-line anti-tuberculosis treatment. Read More

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http://dx.doi.org/10.5588/pha.18.0056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361492PMC
December 2018

How many sputum samples should be examined during follow-up of tuberculosis patients in Myanmar: two or one?

Public Health Action 2018 Dec;8(4):169-174

Department of Public Health, Ministry of Health and Sports, Sagaing, Myanmar.

Ten selected microscopy centres in Sagaing Region, Myanmar, functioning under an external quality assurance system with no reported major errors. To assess the pattern of serial sputum results (NN, both smear-negative; NP, first smear-negative and second smear-positive; PN, first smear-positive and second smear-negative; and PP, both smear-positive) among follow-up sputum microscopy examinations of tuberculosis (TB) patients (end of intensive phase, mid-continuation phase and end of treatment) conducted from 1 November 2017 to 15 April 2018. Cross-sectional study using secondary data (laboratory registers). Read More

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http://dx.doi.org/10.5588/pha.18.0041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361485PMC
December 2018

Non-response to first-line anti-tuberculosis treatment in Sikkim, India: a risk-factor analysis study.

Public Health Action 2018 Dec;8(4):162-168

International Union Against Tuberculosis and Lung Disease South-East Asia Office, New Delhi, India.

Sikkim, India, has the highest proportion of tuberculosis (TB) patients on first-line anti-tuberculosis regimens with the outcome 'failure' or 'shifted to regimen for multidrug-resistant TB (MDR-TB)'. To assess the factors associated with non-response to treatment, i.e. Read More

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http://dx.doi.org/10.5588/pha.18.0026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361490PMC
December 2018