509,175 results match your criteria International journal of gynecological cancer : official journal of the International Gynecological Cancer Society[Journal]


Head and Neck Pain in Patients Presenting with Acute Aortic Dissection.

Aorta (Stamford) 2018 Dec 24;6(6):130-138. Epub 2019 Apr 24.

Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan.

Background:  Head and neck pain is an atypical presentation of acute aortic dissection. Classic teaching associates this pain with proximal dissections, but this has not been extensively studied.

Methods:  Patients enrolled in the International Registry of Acute Aortic Dissection from January 1996 to March 2015 were included in this study. Read More

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http://dx.doi.org/10.1055/s-0039-18388DOI Listing
December 2018

Profile of Pregnant Women with Gestational Diabetes Mellitus at Increased Risk for Large for Gestational Age Newborns.

Rev Bras Ginecol Obstet 2019 Apr 24. Epub 2019 Apr 24.

Endocrinology Unit of University Hospital, Universidade Federal do Maranhão, São Luís, MA, Brazil.

Objective:  Gestational diabetes mellitus (GDM) is associated with a higher risk of perinatal morbidity and mortality, and its main complication is the occurrence of large for gestational age (LGA) newborns. The present study aims to characterize pregnant women with GDM and to identify factors associated with the occurrence of LGA newborns in this population.

Methods:  A cross-sectional study was performed based on medical records of women whose prenatal care and delivery were performed at the Maternal and Child Unit of the Hospital Universitário of the Universidade Federal do Maranhão, state of Maranhão, Brazil. Read More

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http://dx.doi.org/10.1055/s-0039-1687860DOI Listing

Using Artificial Intelligence to Identify Factors Associated with Autism Spectrum Disorder in Adolescents with Cerebral Palsy.

Neuropediatrics 2019 Apr 24. Epub 2019 Apr 24.

Department of Pediatric Orthopaedic Surgery, Lenval University Pediatric Hospital of Nice, Nice, France.

Autism spectrum disorder (ASD) is common in adolescents with cerebral palsy (CP) and there is a lack of studies applying artificial intelligence to investigate this field and this population in particular. The aim of this study is to develop and test a predictive learning model to identify factors associated with ASD in adolescents with CP. This was a multicenter controlled cohort study of 102 adolescents with CP (61 males, 41 females; mean age ± SD [standard deviation] = 16. Read More

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http://dx.doi.org/10.1055/s-0039-1685525DOI Listing

Hospitalization Burden of Biliary Strictures and Cholangitis After Pancreaticoduodenectomy.

J Surg Res 2019 Apr 21;241:95-102. Epub 2019 Apr 21.

Division of Gastroenterology and Hepatology, Rutgers New Jersey Medical School, Newark, New Jersey.

Background: Postsurgical biliary disease in Roux-en-y and cholecystectomies has been investigated, but less literature exists regarding biliary complications after Whipple procedure (pancreaticoduodenectomy [PD]). Moreover, the hospital burden incurred after this complication has not been previously examined. The aim of this study is to assess the trends in hospitalization for biliary strictures and cholangitis after PD. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00224804193017
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http://dx.doi.org/10.1016/j.jss.2019.03.057DOI Listing

Practical considerations for developmental thyroid toxicity assessments: What's working, what's not, and how can we do better?

Regul Toxicol Pharmacol 2019 Apr 21. Epub 2019 Apr 21.

BASF SE, Experimental Toxicology and Ecology, 67056, Ludwigshafen, Germany. Electronic address:

Thyroid hormones (THs; T3 and T4) play a role in development of cardiovascular, reproductive, immune and nervous systems. Thus, interpretation of TH changes from rodent studies (during pregnancy, in fetuses, neonates, and adults) is critical in hazard characterization and risk assessment. A roundtable session at the 2017 Society of Toxicology (SOT) meeting brought together academic, industry and government scientists to share knowledge and different perspectives on technical and data interpretation issues. Read More

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http://dx.doi.org/10.1016/j.yrtph.2019.04.010DOI Listing

Analgesic and anti-inflammatory effects and molecular mechanisms of Kadsura heteroclita stems, an anti-arthritic Chinese Tujia ethnomedicinal herb.

J Ethnopharmacol 2019 Apr 21:111902. Epub 2019 Apr 21.

TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, 410208, PR China. Electronic address:

Ethnopharmacological Relevance: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by failure of spontaneous resolution of inflammation. The stem of Kadsura heteroclite (KHS) is a well-known anti-arthritic Tujia ethnomedicinal plant, which named Xuetong in folk, has long been used for the prevention and treatment of rheumatic and arthritic diseases.

Aim Of The Study: The analgesic and anti-inflammatory effects and the potential mechanisms behind such effects of KHS would be investigated by using different animal models. Read More

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http://dx.doi.org/10.1016/j.jep.2019.111902DOI Listing

Strongly Coupled Pyridine-V O ·nH O Nanowires with Intercalation Pseudocapacitance and Stabilized Layer for High Energy Sodium Ion Capacitors.

Small 2019 Apr 24:e1900379. Epub 2019 Apr 24.

State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Hubei, Wuhan, 430070, P. R. China.

Developing pseudocapacitive cathodes for sodium ion capacitors (SICs) is very significant for enhancing energy density of SICs. Vanadium oxides cathodes with pseudocapacitive behavior are able to offer high capacity. However, the capacity fading caused by the irreversible collapse of layer structure remains a major issue. Read More

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http://dx.doi.org/10.1002/smll.201900379DOI Listing

Trends in tobacco use among adolescents in Spain (2002-2018).

Adicciones 2019 Mar 28;0(0):1111. Epub 2019 Mar 28.

Universidad de Sevilla.

Smoking is the single greatest preventable cause of death in the world today. Adolescence is the developmental period during which smoking is most commonly initiated and addiction is likely to happen. The aim of this study is to examine trends in tobacco use among school-aged adolescents in Spain from 2002 to 2018 by sex and age. Read More

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http://dx.doi.org/10.20882/adicciones.1111DOI Listing

Perinatal hepatitis B virus transmission in Lao PDR: A prospective cohort study.

PLoS One 2019 24;14(4):e0215011. Epub 2019 Apr 24.

Institut de recherche pour le développement (IRD, France), PHPT, Changklan, Muang, Chiang Mai, Thailand.

Background: Mother-to-child transmission of hepatitis B virus (HBV) is the main cause of new infections worldwide. We aimed at assessing the percentage of infants successfully immunized in two major hospitals in Vientiane, Lao PDR where HB immune globulin (HBIg) is not available.

Methods: We studied a prospective cohort of chronically HBV infected pregnant women and their infants until 6 months post-partum from January 2015 to March 2017. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215011PLOS
April 2019
1 Read

Food allergy knowledge, attitudes and their determinants among restaurant staff: A cross-sectional study.

PLoS One 2019 24;14(4):e0214625. Epub 2019 Apr 24.

Family Medicine and Primary Care, Lee Kong Chian School of Medicine, Mandalay, Nanyang Technological University Singapore, Singapore, Singapore.

Background: There is wide international variation regarding food allergy knowledge among restaurant staff. Further, attitudes towards food allergy remain under-researched. Insights into the independent determinants of knowledge and attitudes are limited due to lacking mutual statistical adjustment for determinants/confounders in the vast majority of prior studies. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214625PLOS

Speech-Language Pathology and the Youth Offender: Epidemiological Overview and Roadmap for Future Speech-Language Pathology Research and Scope of Practice.

Authors:
Pamela C Snow

Lang Speech Hear Serv Sch 2019 Apr;50(2):324-339

La Trobe Rural Health School, Bendigo, Victoria, Australia.

Purpose This article is concerned with the growing body of international evidence indicating that adolescents in contact with the youth justice system are likely to have severely compromised oral language skills, receptively and expressively. A smaller, but persuasive, literature also points to poor literacy skills in this population. Language and literacy skills underpin academic, social, and vocational success ( C. Read More

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http://dx.doi.org/10.1044/2018_LSHSS-CCJS-18-0027DOI Listing

Key Aroma Compounds in Oats and Oat Cereals.

J Agric Food Chem 2019 Apr 24. Epub 2019 Apr 24.

Department of Food Science and Technology , Oregon State University , 100 Wiegand Hall , Corvallis , Oregon 97331-6602 , United States.

Oats possess a unique flavor, comprising grain and nut-like sensory characteristics. The first comprehensive study of oat flavor by Heydanek and McGorrin [ Heydanek , M. G. Read More

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http://dx.doi.org/10.1021/acs.jafc.9b00994DOI Listing

Extending expressed RNA genomics from surgical decision making for cytologically indeterminate thyroid nodules to targeting therapies for metastatic thyroid cancer.

Cancer Cytopathol 2019 Apr 24. Epub 2019 Apr 24.

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cncy.22132
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http://dx.doi.org/10.1002/cncy.22132DOI Listing
April 2019
1 Read

Kinetics of Mimivirus Infection Stages Quantified Using Image Flow Cytometry.

Cytometry A 2019 Apr 24. Epub 2019 Apr 24.

Department of Structural Biology, Weizmann Institute of Science, 7610001, Rehovot, Israel.

Due to the heterogeneity of viruses and their hosts, a comprehensive view of viral infection is best achieved by analyzing large populations of infected cells. However, information regarding variation in infected cell populations is lost in bulk measurements. Motivated by an interest in the temporal progression of events in virally infected cells, we used image flow cytometry (IFC) to monitor changes in Acanthamoeba polyphaga cells infected with Mimivirus. Read More

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http://dx.doi.org/10.1002/cyto.a.23770DOI Listing

Case of follicular lymphoma presenting with nodules and plaques on the face.

J Dermatol 2019 Apr 24. Epub 2019 Apr 24.

Department of Dermatology, International University of Health and Welfare, Chiba, Japan.

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http://dx.doi.org/10.1111/1346-8138.14890DOI Listing

A Multi-Institutional International Analysis of Textbook Outcomes Among Patients Undergoing Curative-Intent Resection of Intrahepatic Cholangiocarcinoma.

JAMA Surg 2019 Apr 24:e190571. Epub 2019 Apr 24.

The Ohio State University Wexner Medical Center, Columbus.

Importance: Composite measures may be superior to individual measures for the analysis of hospital performance and quality of surgical care.

Objective: To determine the incidence of a so-called textbook outcome, a composite measure of the quality of surgical care, among patients undergoing curative-intent resection of intrahepatic cholangiocarcinoma.

Design, Setting, And Participants: This cohort study involved an analysis of a multinational, multi-institutional cohort of patient from 15 major hepatobiliary centers in North America, Europe, Australia, and Asia who underwent curative-intent resection of intrahepatic cholangiocarcinoma between 1993 and 2015. Read More

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http://archsurg.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamasurg.2019.0571DOI Listing
April 2019
1 Read

Z-scheme photocatalyst systems employing Rh- and Ir-doped metal oxide materials for water splitting under visible light irradiation.

Faraday Discuss 2019 Apr 24. Epub 2019 Apr 24.

Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan. and Photocatalysis International Research Center, Research Institute for Science and Technology, Tokyo University of Science, 2641, Yamazaki, Noda-shi, Chiba-ken 278-8510, Japan.

Various types of Z-scheme systems for water splitting under visible light irradiation were successfully developed by employing Rh- and Ir-doped metal oxide powdered materials with relatively narrow energy gaps (EG): BaTa2O6:Ir,La (EG: 1.9-2.0 eV), NaTaO3:Ir,La (EG: 2. Read More

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http://dx.doi.org/10.1039/c8fd00209fDOI Listing

Childhood epilepsy with a small number of seizures may be left untreated: an international prospective study.

Epileptic Disord 2019 Apr;21(2):141-153

Department of Paediatrics, Dalhousie University and the IWK Health Centre, Halifax, Nova Scotia, Canada.

It is unknown whether treatment with antiepileptic drugs in children with epilepsy with a presumed good prognosis is always necessary. We aimed to study the course of newly diagnosed epilepsy in children with a presumed good prognosis who are managed without AED treatment. A total of 151 children (one month to 12 years of age) with two to five lifetime unprovoked seizures (excluding febrile convulsions), were followed for three years. Read More

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http://dx.doi.org/10.1684/epd.2019.1040DOI Listing

Review of the International Literature.

Am J Clin Hypn 2019 Apr;61(4):429-433

a Naropa University , Boulder , Colorado.

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http://dx.doi.org/10.1080/00029157.2019.1583962DOI Listing

Low rate of early vertical transmission of HIV supports the feasibility of effective implementation of the national PMTCT guidelines in routine practice of referral hospitals in Cameroon.

Paediatr Int Child Health 2019 Apr 24:1-8. Epub 2019 Apr 24.

l Assistance Publique des Hôpitaux de Paris, Pédiatrie Générale , Hôpital Robert Debré , Paris , France.

Background: Vertical (VT) transmission of HIV remains a public health concern in sub-Saharan Africa.

Objective: To investigate the VT rate and factors associated with transmission in routine practice in three referral hospitals in Cameroon.

Methods: All HIV-infected mothers who delivered in maternity wards or sought paediatric services during the first postnatal week from November 2007 to October 2010 were invited to participate in the ANRS-Pediacam cohort. Read More

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http://dx.doi.org/10.1080/20469047.2019.1585136DOI Listing

To What Extent Are Main Accident-Insurer Cases Representative of All Significantly Injured? A Swiss Monocenter Perspective.

J Insur Med 2019 Apr 24. Epub 2019 Apr 24.

2   Amsler Consulting, Gundeldingerrain 111,CH-4059 Basel (FA).

Even though Switzerland has a compulsory insurance system, there is a lack of detailed information on the treatment and outcome following trauma. The objective of this evaluation was to examine to what extent cases insured by the largest accident-insurer (Suva) are representative of all significantly injured. Trauma center analysis of all ≥16 year old trauma patients with a New Injury Severity Score (NISS) ≥8, comparing the characteristics of Suva- vs non-Suva cases (chi-square; univariate explained variance R; multivariate logistic regression analysis, Nagelkerke R). Read More

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http://dx.doi.org/10.17849/insm-48-1-1-14.1DOI Listing

Effects of an Oil-Free Hydroethanolic Pumpkin Seed Extract on Symptom Frequency and Severity in Men with Benign Prostatic Hyperplasia: A Pilot Study in Humans.

J Med Food 2019 Apr 24. Epub 2019 Apr 24.

3 Frutarom Switzerland Ltd., Scientific Affairs BU Health, Wädenswil, Switzerland.

Majority of men are affected by symptomatic benign prostatic hyperplasia (BPH) from a certain age. Botanical extracts are frequently used in the early management of the symptoms. In a single-arm, mono-center pilot study, the effects of a proprietary oil-free hydroethanolic pumpkin seed extract on the symptoms of BPH were investigated. Read More

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https://www.liebertpub.com/doi/10.1089/jmf.2018.0106
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http://dx.doi.org/10.1089/jmf.2018.0106DOI Listing
April 2019
1 Read

Content validity and readability of patient-reported questionnaire instruments of hearing disability.

Int J Audiol 2019 Apr 24:1-11. Epub 2019 Apr 24.

g NIHR Biomedical Research Centre , University of Nottingham , Nottingham , UK.

Objective: This study evaluates the content validity (i.e. domains assessed) and readability levels of patient-reported questionnaire instruments using internationally recognised procedures and tools. Read More

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https://www.tandfonline.com/doi/full/10.1080/14992027.2019.1
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http://dx.doi.org/10.1080/14992027.2019.1602738DOI Listing
April 2019
1 Read

Prostate cancer dose-response, fractionation sensitivity and repopulation parameters evaluation from 25 international radiotherapy outcome data sets.

Br J Radiol 2019 Apr 24:20180823. Epub 2019 Apr 24.

5 Radiation Therapy, Candiolo Cancer Institute - FPO , IRCCS, Candiolo (To) , Italy.

Objective: This study was undertaken to model the biochemical free survival at 5 years and to evaluate the parameters defining dose-response curve, dose-fractionation radiosensitivity and repopulation.

Methods: It was carried out a literature search on Pubmed to retrieve data sets of patients treated with external beam radiation therapy of 1.8-4. Read More

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http://dx.doi.org/10.1259/bjr.20180823DOI Listing

No time to delay reperfusion: a cross-sectional study of Primary Percutaneous Coronary Intervention times.

J Clin Nurs 2019 Apr 24. Epub 2019 Apr 24.

School of Nursing and Midwifery, Trinity College Dublin, 24 D'Olier Street, Dublin 2, D02T283, Ireland.

Aims And Objectives: To establish and report cross-sectional data of reperfusion times for emergency primary percutaneous coronary interventions (PPCI) and to examine factors associated with times to reperfusion.

Background: Rapid coronary reperfusion can salvage myocardial tissue, preserve left ventricular function and reduce mortality. PPCI is the gold standard of management. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jocn.14892
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http://dx.doi.org/10.1111/jocn.14892DOI Listing
April 2019
1 Read

Side chain rotameric changes and backbone dynamics enable specific cladosporin binding in Plasmodium falciparum lysyl-tRNA synthetase.

Proteins 2019 Apr 24. Epub 2019 Apr 24.

Structural Parasitology, Molecular Medicine Group, International Center for Genetic Engineering and Biotechnology, New Delhi, India.

Cladosporin (CLD) is a fungal metabolite that kills malaria parasite via inhibiting its cytoplasmic lysyl-tRNA synthetase (KRS) and abrogating protein translation. Here we provide structural and drug selectivity analyses on CLD interacting residues in apo and holo KRSs from Plasmodium falciparum, Homo sapiens, Cryptosporidium parvum and Mycobacterium ulcerans. We show that both gross and subtle alterations in protein backbone and sidechains drive the active site structural plasticity that allows integration of CLD in KRSs. Read More

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http://dx.doi.org/10.1002/prot.25699DOI Listing

Analytical validation of a standardized scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicenter collaboration.

Histopathology 2019 Apr 24. Epub 2019 Apr 24.

The Institute of Cancer Research, London, United Kingdom.

Aims: The nuclear proliferation marker Ki67 assayed by immunohistochemistry has multiple potential uses in breast cancer, but an unacceptable level of inter-laboratory variability has hampered its clinical utility. The International Ki67 in Breast Cancer Working Group has undertaken a systematic program to determine whether Ki67 measurement can be analytically validated and standardized across laboratories. This study addresses whether acceptable scoring reproducibility can be achieved on excision whole sections. Read More

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http://dx.doi.org/10.1111/his.13880DOI Listing

[Erratum] MicroRNA-101 inhibits autophagy to alleviate liver ischemia/reperfusion injury via regulating the mTOR signaling pathway.

Int J Mol Med 2019 Jun 9;43(6):2532. Epub 2019 Apr 9.

First Central Clinical College, Tianjin Medical University, Tianjin 300070, P.R. China.

Owing to oversights during the production process, a pair of errors were introduced into the above article. First, in the Materials and methods section, Animals and cell lines subsection, on p. 1332, line 12, the sentence starting here should have read as: 'The non‑tumorigenic mouse hepatocyte alpha mouse liver 12 (AML12) cell line was purchased from the Shanghai Cell Bank of Chinese Academy of Sciences (Shanghai, China)' (i. Read More

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http://dx.doi.org/10.3892/ijmm.2019.4160DOI Listing

Nursing Care in Healthcare-Associated Infections: A Scoping Review.

Rev Bras Enferm 2019 Mar-Apr;72(2):476-483. Epub 2019 Apr 18.

Universidade Federal do Rio Grande do Norte. Natal-RN, Brasil.

Objective: To identify and map nursing care to the adult patient with Healthcare-Associated Infections admitted to the Intensive Care Unit.

Method: Scoping Review, conducted in January 2018, through the search of studies in national and international databases, journals, catalogs of theses and dissertations, and websites of Brazilian health institutions. We included full surveys published in the Portuguese, Spanish or English language; which had as object of study the researched subject, besides manuals and protocols. Read More

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http://dx.doi.org/10.1590/0034-7167-2018-0418DOI Listing

Contributions of the nurse's clinical practice to Primary Care.

Rev Bras Enferm 2019 Mar-Apr;72(2):354-359. Epub 2019 Apr 18.

Universidade Federal de Santa Catarina. Florianópolis-SC, Brasil.

Objective: To understand the repercussions of the nurse's clinical practice on Primary Health Care.

Method: Qualitative research with the theoretical and methodological contribution of Grounded Theory. Data collection took place between May and October 2016 in Florianópolis' Primary Care service. Read More

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http://dx.doi.org/10.1590/0034-7167-2018-0348DOI Listing

Reaching 90-90-90: outcomes of a 15-year multi-country HIV workplace programme in sub-Saharan Africa.

Antivir Ther 2019 Apr 24. Epub 2019 Apr 24.

Department Global Health and Safety, Heineken International B.V., Amsterdam, the Netherlands.

Background: In 2001, an international beverage company implemented an HIV workplace program providing free antiretroviral treatment (ART) for employees and dependents in sub-Saharan Africa, at a time when ART, cost assessments of ART programs and related public funding was hardly available. This study describes the outcomes of this program with respect to achieving the UNAIDS 90-90-90 targets in 5 African countries and analyzes trends over the past 15 years.

Methods: Anonymous human resource data were analyzed in three cohorts of participants (those enrolling in 2001-2005, 2006-2010, and 2011-2015). Read More

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http://dx.doi.org/10.3851/IMP3311DOI Listing

Cross-border nursing education: questions, qualms and quality assurance.

Int J Health Care Qual Assur 2019 Mar;32(2):375-384

Faculty of Health Sciences, Durban University of Technology , Durban, South Africa.

Purpose: The purpose of this paper is to share insights, research findings and discuss key issues relating to quality practices and quality assurance in cross-border nursing education program development and implementation.

Design/methodology/approach: The authors used a qualitative, multiple case-study approach, by sampling local, national and international nursing education institutions, academia and nurse graduates to identify challenges and best operating practices in implementing and facilitating cross-border education.

Findings: The authors reveal that quality assurance affects cross-border nursing education program design, delivery and implementation. Read More

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http://dx.doi.org/10.1108/IJHCQA-02-2018-0060DOI Listing

Iranian hospital efficiency: a systematic review and meta-analysis.

Int J Health Care Qual Assur 2019 Mar;32(2):385-397

Research Center for Environmental Determinants of Health, Kermanshah University of Medical Sciences , Kermanshah, Iran.

Purpose: The purpose of this paper (systematic review and meta-analysis) is to synthesize and analyze studies that assessed Iranian hospital efficiency.

Design/methodology/approach: A systematic literature search was conducted using both international (the Institute for Scientific Information, Scopus and PubMed) and Iranian scientific (Magiran, IranMedex and Scientific Information Database) databases. The review included original studies that used the Pabon Lasso Model to examine Iranian hospital performance, published in Persian or English. Read More

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http://dx.doi.org/10.1108/IJHCQA-03-2018-0067DOI Listing

Hospital quality indicators: a systematic review.

Int J Health Care Qual Assur 2019 Mar;32(2):474-487

Hospital Moinhos de Vento, Porto Alegre, Brazil.

Purpose: The purpose of this paper is to identify and describe hospital quality indicators, classifying them according to Donabedian's structure, process and outcome model and in specific domains (quality, safety, infection and mortality) in two care divisions: inpatient and emergency services.

Design/methodology/approach: A systematic review identified hospital clinical indicators. Two independent investigators evaluated 70 articles/documents located in electronic databases and nine documents from the grey literature, 35 were included in the systematic review. Read More

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https://www.emeraldinsight.com/doi/10.1108/IJHCQA-04-2018-00
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http://dx.doi.org/10.1108/IJHCQA-04-2018-0091DOI Listing

Change of trends in the treatment modality for pediatric nephrolithiasis: Retrospective analysis of a US-based insurance claims database.

J Endourol 2019 Apr 24. Epub 2019 Apr 24.

Stanford University Medical Center, 10623, Urology, Stanford, California, United States ;

Purpose: The objective of this study was to show the prevalence and investigate treatment trends of pediatric nephrolithiasis based on a large population of US insurance individual's data.

Materials And Methods: This research involved a retrospective observational cohort study. Administrative claims data were extracted from the IBM® MarketScan Research Database. Read More

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http://dx.doi.org/10.1089/end.2019.0154DOI Listing

Benzo-Fused Periacenes or Double Helicenes? Different Cyclodehydrogenation Pathways on Surface and in Solution.

J Am Chem Soc 2019 Apr 23. Epub 2019 Apr 23.

Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Joint International Research Laboratory of Carbon-Based Functional Materials and Devices , Soochow University , Suzhou 215123 , China.

Controlling the regioselectivity of C-H activation in unimolecular reactions is of great significance for the rational synthesis of functional graphene nanostructures, which are called nanographenes. Here, we demonstrate that the adsorption of tetranaphthyl- p-terphenyl precursors on metal surfaces can completely change the cyclodehydrogenation route and lead to obtaining planar benzo-fused perihexacenes rather than double [7]helicenes during solution synthesis. The course of the on-surface planarization reactions is monitored using scanning probe microscopy, which unambiguously reveals the formation of dibenzoperihexacenes and the structures of reaction intermediates. Read More

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http://dx.doi.org/10.1021/jacs.9b01267DOI Listing

[Discussion on strategies of health literacy promotion for echinococcosis control in China].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2019 Apr;31(1):94-97

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; WHO Collaborating Center for Tropical Diseases; Key Laboratory of Parasite and Vector Biology, National Health Commission; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China.

This article analyzes recent progresses on health education and health promotion targeting echinococcosis control in the major endemic foci of China, and describes the problems, including lack of human echinococcosis control knowledge, low human health literacy levels, incomplete establishment of health promotion mode, and urgent efforts to achieve the goal of Health for All. In addition, the feasible measures and strategies on health literacy promotion for echinococcosis control are discussed in combination with the national health literacy promotion strategy according to Healthy China 2030. Read More

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http://dx.doi.org/10.16250/j.32.1374.2019023DOI Listing

[Progress of research on the interplay between helminth and intestinal protozoa and gut microbiota].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2019 Mar;31(1):77-85

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology; Key Laboratory of Parasite and Vector Biology, National Health Commission, Shanghai 200025, China.

As the largest and most complex ecosystem in humans, gut microbiota resides in human or animal gastrointestinal tract with intestinal viruses and parasites. Previous studies have demonstrated that gut microbiotadysbiosis is strongly correlated with the development, progression and prognosis of multiple diseases. The parasites that are colonized in the host, may directly or indirectly affect gut microbiota and the gut microbiota-host homeostasis, and changes in the composition and diversity of gut microbiota may also affect parasitic infections and the development, progression and prognosis of parasitic diseases. Read More

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http://dx.doi.org/10.16250/j.32.1374.2019005DOI Listing

[Epidemic status and control of tick-borne parasitic diseases in China].

Authors:
Li Lan-Hua Zhang Yi

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2019 Mar;31(1):58-62

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Key Laboratory of Parasite and Vector Biology of National Health Commission, China.

Recently, both of the species of tick-borne parasites and cases of tick-borne parasitic diseases in human beings are increasing in China. Tick-borne diseases are considered to be an important public health problem affecting the health of Chinese. In this paper, we summarize the epidemic status and control measures of tick-borne parasitic diseases in China, and put forward that the epidemic status of tick-borne parasitic diseases may be greatly underestimated in China, and the systematic surveillance of tick-borne parasitic diseases on population, vectors and animal hosts is urgently needed. Read More

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http://dx.doi.org/10.16250/j.32.1374.2018310DOI Listing

[Current status and transmission risks of oversea imported schistosomiasis in China].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2019 Mar;31(1):26-32

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, China.

With the acceleration of the process of global integration, China's international exchanges and cooperation with other countries have been further increased. The personnel exchange has led to the frequent occurrence of imported schistosomiasis from abroad, which seriously endangers people's health. This paper reviews the prevalence and transmission risks of oversea imported schistosomiasis, providing the reference for the entry and exit health quarantine and prevention and control of schistosomiasis in China. Read More

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http://dx.doi.org/10.16250/j.32.1374.2019021DOI Listing

[A path analysis on China's participation in global health governance: a case study of China Aid of Schistosomiasis Control in Zanzibar].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2019 Mar;31(1):14-18

Key Laboratory of National Health Commission on Parasitic Diseases Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China.

Recently, China's participation in global health governance has been paid increasing global attention. This paper analyzed the current status and needs of African schistosomiasis control, the participation of China and international organizations in African schistosomiasis control and the progress of China Aid of Schistosomiasis Control in Zanzibar, with China Aid of Schistosomiasis Control in Zanzibar as an example. It is suggested that China may improve the capability of participation in global public health governance and international reputation through strengthening intergovernmental and international collaborations, providing successful disease control experiences and products and improving capability and team building. Read More

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http://dx.doi.org/10.16250/j.32.1374.2019041DOI Listing

[Upholding Chinese spirit on schistosomiasis control in the new era to accelerate the progress towards schistosomiasis elimination in China].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2019 Apr;31(1):1-13

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Key Laboratory of Parasite and Vector Biology of National Health Commission, Shanghai 200025, China.

China is one of the schistosomiasis-endemic countries with the highest burden of disease across the world. Following the control efforts for over 60 years, great successes have been achieved in schistosomiasis control in the country, and the control program is moving towards transmission interruption and elimination. To commemorate the 60th anniversary of publishing Chairman Mao Zedong's two poems entitled "", a series of activities that disseminate schistosomiasis control achievements have been conducted in China throughout 2018, including the development of Chinese spirit on schistosomiasis control in the new era. Read More

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http://dx.doi.org/10.16250/j.32.1374.2019043DOI Listing

Underestimated Burden: Non-Communicable Diseases in North Korea.

Authors:
Shin Ha Yo Han Lee

Yonsei Med J 2019 May;60(5):481-483

Department of Preventive Medicine, Konyang University College of Medicine, Daejeon, Korea.

There remains a misperception that non-communicable diseases (NCDs) are predominantly an issue for developed countries and are not major public health problems in low-income countries. North Korea is also often considered as a country with a disease structure that is typical of a low-income country. Infectious diseases and nutritional problems, including tuberculosis and pneumonia, are still major sources of medical discussion. Read More

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http://dx.doi.org/10.3349/ymj.2019.60.5.481DOI Listing

Comparison of Radiological and Histological Findings of Lung Parenchyma in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Yonsei Med J 2019 May;60(5):454-460

Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

Purpose: The present study investigated chest computed tomography (CT) patterns and lung histological features, as well as the consistency between radiological and histological features among patients with microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA), and eosinophilic GPA (EGPA).

Materials And Methods: The medical records of 74 antineutrophil cytoplasmic antibody-associated vasculitis (AAV) patients with radiological lung parenchymal lesions were reviewed along with the histological results for 28 of them. Chest CT patterns were divided according 12 items mostly suggested by radiologists and histological features were divided according to necrotising granuloma, necrotising vasculitis, eosinophilic infiltration, and hemosiderin laden macrophages as defined by a pathologist. Read More

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http://dx.doi.org/10.3349/ymj.2019.60.5.454DOI Listing

COPD as a Disease of Immunosenescence.

Yonsei Med J 2019 May;60(5):407-413

Severance Biomedical Science Institute and BK21 PLUS Project for Medical Sciences, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Although chronic obstructive pulmonary disease (COPD) is regarded as a chronic inflammatory lung disease, the disease mechanism is still not known. Intriguingly, aging lungs are quite similar to COPD-affected lungs in many ways, and COPD has been viewed as a disease of accelerated premature aging of the lungs. In this paper, based on a literature review, we would like to propose immunosenescence, age-associated decline in immunity, as a critical mechanism for the development of COPD. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.3349/ymj.2019.60
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http://dx.doi.org/10.3349/ymj.2019.60.5.407DOI Listing
May 2019
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Analysis of Global Drug Development Pathways and Postmarketing Safety in Japan: Local Studies May Reduce Drug-Related Deaths.

Clin Transl Sci 2019 Apr 23. Epub 2019 Apr 23.

Laboratory of Pharmaceutical Regulatory Science, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

Recent International Conference on Harmonization (ICH) guidelines provide pharmaceutical companies with regulatory justifications to pursue various global drug-development pathways, in some of which "local" dose-ranging and/or pivotal phase III studies are skipped. We examined the association between the clinical development pathway and postmarketing safety in Japan for 177 new molecular entities approved between 2004 and 2013 focusing on dose setting histories for each drug. The risk of drug-related deaths was higher when companies did not conduct local (i. Read More

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http://dx.doi.org/10.1111/cts.12631DOI Listing

What Can Be Learned From Crowdsourced Population Asparagus Urinary Odor Kinetics?

CPT Pharmacometrics Syst Pharmacol 2019 Apr 23. Epub 2019 Apr 23.

Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, USA.

Asparagus consumption is associated with the production of malodorous urine. Interindividual variability was previously characterized by an American Society for Clinical Pharmacology and Therapeutics crowdsourced study. To further characterize urinary odor kinetics, we conducted a study with consenting participants from Takeda Pharmaceutical International Company. Read More

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http://dx.doi.org/10.1002/psp4.12401DOI Listing

Enhanced Photodetection Properties of Tellurium@Selenium Roll-to-Roll Nanotube Heterojunctions.

Small 2019 Apr 24:e1900902. Epub 2019 Apr 24.

SZU-NUS Collaborative Innovation Centre for Optoelectronic Science & Technology, and Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, P. R. China.

Non-layered tellurium (Te) is a promising material for applications in transistor and optoelectronic devices for its advantages in excellent intrinsic electronic and optoelectronic properties. However, the poor photodetection performance and relatively uncertain stability of tellurene under ambient conditions greatly limit the practical applications. In order to improve the performance of tellurene-based materials, Te@Se roll-to-roll nanotubes with different selenium (Se) contents synthesized by epitaxial growth of Se on Te nanotubes are, for the first time, employed to fabricate working electrodes for photoelectrochemical (PEC)-type broadband photodetection. Read More

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http://dx.doi.org/10.1002/smll.201900902DOI Listing

Review article: A primer for clinical researchers in the emergency department: Part VIII. Implementation science: An introduction.

Emerg Med Australas 2019 Apr 24. Epub 2019 Apr 24.

Nursing Research Institute, St Vincent's Health Australia and Australian Catholic University, Sydney, New South Wales, Australia.

New research findings may not lead to change in practice, or a change at the front line may be delayed by years. A number of terms have been used to describe efforts and strategies to speed a change in evidence-based practice, such as: implementation science, knowledge translation, research translation and others. In contrast to traditional clinical research, implementation science generally aims to understand and change health professional behaviour to promote evidence uptake as opposed to attempting to change patient behaviour. Read More

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http://dx.doi.org/10.1111/1742-6723.13296DOI Listing

"Immuno-flowFISH" for the Assessment of Cytogenetic Abnormalities in Chronic Lymphocytic Leukemia.

Cytometry A 2019 Apr 24. Epub 2019 Apr 24.

Translational Cancer Pathology Laboratory, School of Biomedical Sciences, The University of Western Australia, Crawley, Western Australia, Australia.

Imaging flow cytometry is emerging as a diagnostic tool for the assessment of leukemia. It has the functionality of standard flow cytometry and generates high-resolution digital images of each cell with quantifiable numerical data. We demonstrate the use of an automated high-throughput method for performing fluorescence in situ hybridization (FISH) on immunophenotyped whole cells in suspension and analyzed by imaging flow cytometry, a technique called "Immuno-flowFISH". Read More

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http://dx.doi.org/10.1002/cyto.a.23769DOI Listing
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