4,139 results match your criteria International journal of geriatric psychiatry[Journal]


Problem solving therapy reduces subjective burden levels in caregivers of family members with mild cognitive impairment or early-stage dementia: Secondary analysis of a randomized clinical trial.

Int J Geriatr Psychiatry 2019 Mar 14. Epub 2019 Mar 14.

Departments of Psychiatry, Biostatistics, Epidemiology, Psychology and Clinical and Translational Science, University of Pittsburgh Schools of Medicine and Public Health, Pittsburgh, PA, USA.

Objectives: Interventions addressing burden have limited impact among long-term family caregivers. We examined whether problem solving therapy (PST) would reduce burden levels of caregivers of individuals diagnosed with mild cognitive impairment (MCI) or early-stage dementia (AD).

Methods: Caregivers (N = 73) randomly received PST or nutritional training (NT). Read More

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http://dx.doi.org/10.1002/gps.5095DOI Listing

Episodic density, subsyndromic symptoms and mood instability in late-life bipolar disorders: a 5-year follow-up study.

Int J Geriatr Psychiatry 2019 Mar 12. Epub 2019 Mar 12.

ÁREA, Assistance and Research in Affective Disorders, Buenos Aires, Argentina.

Objectives: Characterization of clinical course in Old Age Bipolar Disorder (OABD) is scarce and based solely on Episode Density (ED). The aim of this study was to explore Mood Instability (MI) and Subsyndromal Symptomatology (SS) in a prospective cohort of OABD. Further, we contrasted these measures with a cohort of Young Age Bipolar Disorder (YABD). Read More

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http://dx.doi.org/10.1002/gps.5094DOI Listing

Risk of dementia and mild cognitive impairment among older adults in same-sex relationships.

Int J Geriatr Psychiatry 2019 Mar 12. Epub 2019 Mar 12.

University of Kansas Alzheimer's Disease Center, Fairway, KS, USA.

Introduction: Sexual minority discrimination might lead to a higher risk of mild cognitive impairment (MCI) and dementia. The aim of this study was to assess the risk of MCI and dementia between older adults in same-sex relationships (SSR) and opposite-sex relationships (OSR).

Methods: We analyzed longitudinal data from the National Alzheimer's Coordinating Center up to September 2017. Read More

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http://dx.doi.org/10.1002/gps.5092DOI Listing

Unilateral and Bilateral Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Late-Life Depression.

Int J Geriatr Psychiatry 2019 Mar 10. Epub 2019 Mar 10.

Department of Psychiatry, University of Toronto.

Background: The management of late-life depression is challenged by high rates of treatment-resistance and adverse effects, along with medical comorbidities and polypharmacy. Together with the limited data on managing treatment-resistant depression in older adults, there is a need for investigating the efficacy of non-pharmacological treatment strategies. Repetitive transcranial magnetic stimulation (rTMS) is one modality that may better serve this patient population. Read More

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http://dx.doi.org/10.1002/gps.5091DOI Listing

Machine learning approaches to studying the role of cognitive reserve in conversion from mild cognitive impairment to dementia.

Int J Geriatr Psychiatry 2019 Mar 10. Epub 2019 Mar 10.

Department of Developmental and Educational Psychology, Universidade de Santiago de Compostela, Santiago de Compostela.

Objectives: The overall aim of the present study was to explore the role of Cognitive Reserve (CR) in the conversion from Mild Cognitive Impairment (MCI) to dementia. We used traditional and Machine Learning (ML) techniques to compare converter and non-converter participants. We also discuss the predictive value of CR proxies in relation to the ML model performance. Read More

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http://dx.doi.org/10.1002/gps.5090DOI Listing

Awareness and its relationships with neuropsychiatric symptoms in people with Korsakoff syndrome or other alcohol-related cognitive disorders living in specialized nursing homes.

Int J Geriatr Psychiatry 2019 Mar 10. Epub 2019 Mar 10.

Department of General Practice and Elderly Care Medicine, Amsterdam Public Health research institute, VU University Medical Center, MB, Amsterdam, The Netherlands.

Objectives: Impaired awareness of functional deficits is often observed in people with Korsakoff syndrome (KS) and may result in refusal of care, although this area has been understudied. This study aimed to investigate levels of impaired awareness and their relationships with neuropsychiatric symptoms (NPS) in people with KS residing in specialized nursing homes.

Methods: A cross-sectional, observational study was conducted among 215 residents with KS or other alcohol-related cognitive disorders. Read More

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http://doi.wiley.com/10.1002/gps.5093
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http://dx.doi.org/10.1002/gps.5093DOI Listing
March 2019
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Association of anxiety symptoms with health care use and costs in people aged 85 and over.

Int J Geriatr Psychiatry 2019 Mar 1. Epub 2019 Mar 1.

Department of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Objective: To analyze the association of anxiety symptoms with health care use and costs in people aged 85 and older.

Methods: Baseline data from AgeQualiDe (N = 856), a multicenter prospective cohort study of primary care patients aged 85 and older, were analyzed. Anxiety symptoms (Geriatric Anxiety Inventory-Short Form) and health care use were assessed via questionnaires. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/gps.5089
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http://dx.doi.org/10.1002/gps.5089DOI Listing
March 2019
3 Reads

Delirium and Alzheimer disease: A proposed model for shared pathophysiology.

Int J Geriatr Psychiatry 2019 Feb 17. Epub 2019 Feb 17.

Aging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.

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http://dx.doi.org/10.1002/gps.5088DOI Listing
February 2019
4 Reads

Anticholinergic burden before and after hospitalization in older adults with dementia: increase due to antipsychotic medications.

Int J Geriatr Psychiatry 2019 Feb 13. Epub 2019 Feb 13.

Leibniz Institute for Prevention Research and Epidemiology BIPS, Bremen, Germany.

Objectives: To evaluate changes in the use of antipsychotics and medications with anticholinergic activity (MACs) during hospitalization in older adults with dementia and factors associated with antipsychotic prescriptions and increased anticholinergic burden (ACB).

Methods And Design: This retrospective cohort study included all patients aged ≥65 years with a discharge diagnosis of dementia hospitalized at the university hospital of Udine, Italy, 2012-2014. Medications dispensed within 3 months before and after hospitalization, respectively, were identified in community-pharmacy dispensations while those prescribed at discharge were collected from Hospital Electronic Medical Records (EMR). Read More

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http://dx.doi.org/10.1002/gps.5084DOI Listing
February 2019

Increased ventromedial prefrontal cortex activity and connectivity predict poor sertraline treatment outcome in late-life depression.

Int J Geriatr Psychiatry 2019 Feb 13. Epub 2019 Feb 13.

Department of Psychiatry, University of Connecticut Health Center, Farmington, CT, USA.

Objective: Previous studies of imaging predictors on acute treatment response in late-life depression (LLD) demonstrated that poor response to selective serotonin reuptake inhibitors (SSRIs) is associated with pre-treatment low functional connectivity (FC) within executive control network and high FC within default-mode network including the ventromedial prefrontal cortex (vmPFC). However, there is less research in regional resting-state functional activity that explains FC changes related to SSRI response.

Methods: Thirty-six older major depressive disorder (MDD) patients not currently on antidepressant treatment had a baseline, pre-treatment resting-state functional magnetic resonance imaging scan, followed by sertraline treatment for 12 weeks. Read More

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http://dx.doi.org/10.1002/gps.5079DOI Listing
February 2019
2.866 Impact Factor

The relationship between basic, instrumental and advanced activities of daily living and executive functioning in geriatric patients with neurocognitive disorders.

Int J Geriatr Psychiatry 2019 Feb 14. Epub 2019 Feb 14.

Frailty in Ageing Research Group (FRIA), Vrije Universiteit Brussel, Brussels, (Belgium).

Objective: Although many studies explored the relationship between executive functions (EF) and activities of daily living (ADLs) in cognitive disorders, previous studies used measurements without well-defined levels of ADLs. This study explored the relationship between EF and the threefold classification of everyday functioning; basic or b-, instrumental or i-, and advanced or a-ADLs, and examined how EF account for the variance in this triad of everyday functioning.

Methods: A sample of 44 cognitively healthy persons, 41 persons with Mild Cognitive Impairment and 35 persons with Alzheimer's Disease were assessed with comprehensive measures of EF and the b-, i- and a-ADL tools. Read More

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http://dx.doi.org/10.1002/gps.5087DOI Listing
February 2019
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Intra-operative Blood Transfusion Predicts Post-Operative Delirium among Older Patients Undergoing Elective Orthopedic Surgery: a Prospective Cohort Study.

Int J Geriatr Psychiatry 2019 Feb 13. Epub 2019 Feb 13.

Aging and Health Research Center, National Yang Ming University, Taipei, Taiwan.

Objectives: To evaluate the roles of preoperative anemia and intra-operative blood transfusion in the development of post-operative delirium among older patients undergoing elective orthopedic surgery.

Methods: This prospective cohort study recruited subjects aged 60 years and over who were admitted for elective orthopedic surgery in a tertiary medical center during April 2011 to December 2013. Demographic data (age, gender, BMI, educational level), surgery-related factors (ASA class, type of anesthesia and surgery, intra-operative blood transfusion), results of geriatric assessment (hearing/visual impairment, cognition, depressive mood, comorbidity, malnutrition, polypharmacy, ADL, and IADL), laboratory data, length of hospital stay and the development of post-operative delirium were collected for analysis. Read More

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http://dx.doi.org/10.1002/gps.5086DOI Listing
February 2019
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The relationship between the frequency of number-puzzle use and baseline cognitive function in a large online sample of adults aged 50 and over.

Int J Geriatr Psychiatry 2019 Feb 11. Epub 2019 Feb 11.

University of Exeter Medical School, University of Exeter, Exeter, UK.

Objective: Establishing affordable lifestyle interventions that might preserve cognitive function in the aging population and subsequent generations is a growing area of research focus. Data from the PROTECT study has been utilised to examine whether number-puzzle use is related to cognitive function in older adults.

Methods: Data from 19 078 healthy volunteers aged 50 to 93 years old enrolled on the online PROTECT study were evaluated for self-reported frequency of performing number puzzles. Read More

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http://dx.doi.org/10.1002/gps.5085DOI Listing
February 2019

The recall of dementia-related and neutral words by people with dementia: The ironic process of thought suppression.

Int J Geriatr Psychiatry 2019 Feb 7. Epub 2019 Feb 7.

University of the West of England, Bristol, UK.

Objective: Thought suppression may not work effectively when people have a cognitive impairment. This study tests whether participants with dementia showed lessened or enhanced recall and recognition of dementia-related words compared to a control population.

Methods: Fifty participants living with dementia with mild levels of cognitive impairment and a control group of fifty-two participants without a diagnosis of dementia took part. Read More

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http://dx.doi.org/10.1002/gps.5083DOI Listing
February 2019
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Caregiver burden and quality of life 2 years after attendance at a memory clinic.

Int J Geriatr Psychiatry 2019 Feb 7. Epub 2019 Feb 7.

Department of Health Services Research & Policy, London School of Hygiene & Tropical Medicine, London, UK.

Objectives: We aimed to describe (1) the burden and health-related quality of life (HRQL) of informal caregivers of new patients attending a memory assessment service (MAS), (2) changes in these outcomes over 2 years, and (3) satisfaction with services.

Methods: Informal caregivers of patients attending one of 73 MASs throughout England completed questionnaires at the patient's first appointment, and 6 and 12 months later. Participants from 30 of these MASs were also followed up at 24 months. Read More

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http://dx.doi.org/10.1002/gps.5060DOI Listing
February 2019

Associations among Braak stage, Parkinsonian gait, cognition, and functional status in autopsy-confirmed dementia with Lewy bodies.

Int J Geriatr Psychiatry 2019 Feb 6. Epub 2019 Feb 6.

Shiley-Marcos Alzheimer's Disease Research Center, University of California San Diego, San Diego, CA.

Objective: Compromised functional abilities in older adults with dementia with Lewy bodies (DLB) represent a significant burden to families and frequently lead to institutionalization. Contributing factors to this compromise are poorly understood.

Methods: Using data collected at a first study visit, multiple regression modeling was used to examine the associations between Braak staged Alzheimer disease (AD) pathology, Apolipoprotein E (ApoE) status, Parkinsonian gait, cognition, and functional status from a cohort of 102 cases with an autopsy-confirmed diagnosis of dementia stemming from combined Lewy body and AD pathology. Read More

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http://dx.doi.org/10.1002/gps.5080DOI Listing
February 2019
1 Read

Verbal Fluency and Risk of Dementia.

Int J Geriatr Psychiatry 2019 Feb 6. Epub 2019 Feb 6.

Florida State University College of Medicine, Tallahassee, FL, USA.

Objective: Verbal fluency is a common neuropsychological test that is impaired in dementia. We test whether verbal fluency is a prospective risk factor for incident dementia, cognitive impairment not dementia (CIND), and conversion from CIND to dementia.

Methods: Participants (N=18,189) from the Health and Retirement Study were administered a standard test of verbal fluency and were assessed for cognitive status every two years between baseline and six years follow-up. Read More

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http://dx.doi.org/10.1002/gps.5081DOI Listing
February 2019

Relationship quality and sense of coherence in dementia: Results of a European cohort study.

Int J Geriatr Psychiatry 2019 Feb 7. Epub 2019 Feb 7.

CEDOC, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.

Objective: Quality of life of people with dementia and their family carers is strongly influenced by interpersonal issues and personal resources. In this context, relationship quality (RQ) and sense of coherence (SOC) potentially protect and promote health. We aimed to identify what influences RQ in dyads of people with dementia and their carers and to examine differences in their perspectives. Read More

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http://dx.doi.org/10.1002/gps.5082DOI Listing
February 2019
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Measurement validity of the Patient-Health Questionnaire-9 in US nursing home residents.

Int J Geriatr Psychiatry 2019 Feb 6. Epub 2019 Feb 6.

Center for Gerontology and Healthcare Research, Department of Health Services, Policy and Practice, Brown University School of Public Health, Providence, RI, United States.

Objectives: The objective of this study was to assess the measurement properties of the self-reported Patient Health Questionnaire-9 (PHQ-9) and its 10-item observer version (PHQ-10OV) among nursing home residents.

Methods: We conducted a retrospective study of Minimum Data Set 3.0 assessments for national cohorts of Medicare Fee-for-Service beneficiaries who were newly admitted or incident long-stay residents in 2014-2015 at US nursing homes (NHs) certified by the Center for Medicare and Medicaid Services. Read More

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http://dx.doi.org/10.1002/gps.5074DOI Listing
February 2019
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Pain assessment and pain treatment for community-dwelling people with dementia: A systematic review and narrative synthesis.

Int J Geriatr Psychiatry 2019 Feb 6. Epub 2019 Feb 6.

Research Institute for Primary Care and Health Sciences, Keele University, Staffordshire, UK.

Objectives: To describe the current literature on pain assessment and pain treatment for community-dwelling people with dementia.

Method: A comprehensive systematic search of the literature with narrative synthesis was conducted. Eight major bibliographic databases were searched in October 2018. Read More

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http://dx.doi.org/10.1002/gps.5078DOI Listing
February 2019
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Individual goal-oriented cognitive rehabilitation to improve everyday functioning for people with early-stage dementia: A multicentre randomised controlled trial (the GREAT trial).

Int J Geriatr Psychiatry 2019 Feb 6. Epub 2019 Feb 6.

Dementia Services Development Centre, Bangor University, Bangor, UK.

Objectives: To determine whether individual goal-oriented cognitive rehabilitation (CR) improves everyday functioning for people with mild-to-moderate dementia.

Design And Methods: Parallel group multicentre single-blind randomised controlled trial (RCT) comparing CR added to usual treatment (CR) with usual treatment alone (TAU) for people with an ICD-10 diagnosis of Alzheimer, vascular or mixed dementia, and mild-to-moderate cognitive impairment (Mini-Mental State Examination [MMSE] score ≥ 18), and with a family member willing to contribute. Participants allocated to CR received 10 weekly sessions over 3 months and four maintenance sessions over 6 months. Read More

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http://dx.doi.org/10.1002/gps.5076DOI Listing
February 2019
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Depression in carers of people with dementia from a minority ethnic background: Systematic review and meta-analysis of randomised-controlled trials of psychosocial interventions.

Int J Geriatr Psychiatry 2019 Feb 4. Epub 2019 Feb 4.

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Objectives: Systematic review and meta-analysis to determine the effectiveness of interventions in reducing depressive symptoms in ethnic minority carers of people with dementia.

Methods: We systematically searched EMBASE, CINAHL, MEDLINE, PsycINFO, PsycARTICLES, Applied Social Sciences Index and Abstracts (ASSIA), The Cochrane Central Register of Controlled Trials (CENTRAL), Sociological Abstracts and Social Policy and Practices databases from 1990 to 2015, supplemented by a grey literature search, hand searches of bibliographies and contacting authors. Study quality was assessed independently by two researchers using The Effective Public Health Practice Project Quality Assessment Tool, with an inter-rater reliability of Cohen's kappa of 0. Read More

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http://dx.doi.org/10.1002/gps.5070DOI Listing
February 2019
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Prevalence and determinants of subjective cognitive decline in a representative Greek elderly population.

Int J Geriatr Psychiatry 2019 Feb 3. Epub 2019 Feb 3.

Department of Social Medicine, Psychiatry and Neurology, National and Kapodistrian University of Athens, 1st Department of Neurology, Aeginition University Hospital, Athens, Greece.

Objectives: We studied the prevalence of subjective cognitive decline (SCD) and its determinants in a sample of 1456 cognitively normal Greek adults ≥65 years old.

Methods/design: Subjects were evaluated by a multi-disciplinary team on their neurological, medical, neuropsychological and lifestyle profile to reach consensus diagnoses. We investigated various types of SCD, including single-question, general memory decline, specific subjective memory decline based on a list of questions and three types of subjective naming, orientation and calculation decline. Read More

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http://dx.doi.org/10.1002/gps.5073DOI Listing
February 2019
3 Reads

Quality of education impacts late life cognition.

Int J Geriatr Psychiatry 2019 Feb 3. Epub 2019 Feb 3.

University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

Objectives: Screening tests of global cognition detect racial differences in scores even after adjustment for educational attainment. Differential educational environments in adolescence may affect individual cognitive function. This study examines the impact of high school educational quality on late-life cognition among community-dwelling older adults. Read More

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http://dx.doi.org/10.1002/gps.5075DOI Listing
February 2019
2 Reads

Cognitive behavioral therapy improves diverse profiles of depressive symptoms in Parkinson's disease.

Int J Geriatr Psychiatry 2019 Feb 4. Epub 2019 Feb 4.

Department of Psychiatry, Rutgers-Robert Wood Johnson Medical School, Piscataway, New Jersey.

Objective: Depression is among the most common and debilitating nonmotor complaints in Parkinson's disease (PD), yet there is a paucity of controlled research to guide treatment. Little research has focused on the extent to which specific depressive symptom profiles may dictate unique clinical recommendations to ultimately improve treatment outcomes. The current study examined the impact of cognitive behavioral therapy (CBT) on different types of depressive symptoms in PD. Read More

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http://dx.doi.org/10.1002/gps.5077DOI Listing
February 2019
1 Read

Imaging in prodromal dementia with Lewy bodies: Where do we stand?

Int J Geriatr Psychiatry 2019 Feb 3. Epub 2019 Feb 3.

Campus for Ageing and Vitality, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.

Objectives: The aim of this review was to provide an overview of the literature on imaging in prodromal dementia with Lewy bodies (DLB).

Design: Systematic PubMed search and literature review.

Results: Diagnostic classification of the prodromal DLB stage remains to be established but is likely to require imaging biomarkers to improve diagnostic accuracy. Read More

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http://doi.wiley.com/10.1002/gps.5071
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http://dx.doi.org/10.1002/gps.5071DOI Listing
February 2019
6 Reads

The usefulness of visual rating of posterior atrophy in predicting rapid cognitive decline in Alzheimer disease: A preliminary study.

Int J Geriatr Psychiatry 2019 Apr 20;34(4):625-632. Epub 2019 Feb 20.

Department of Neurology, Seoul National University Bundang Hospital, Seongnam, South Korea.

Background: Approximately 10% to 30% of Alzheimer disease (AD) patients progress rapidly in severity and become more dependent on caregivers. Although several studies have investigated whether imaging biomarkers such as medial temporal atrophy (MTA) and posterior atrophy (PA) are useful for predicting the rapid progression of AD, their results have been inconsistent.

Objective: The study aims to investigate the association of visually rated MTA and PA with rapid disease progression in AD. Read More

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http://dx.doi.org/10.1002/gps.5072DOI Listing
April 2019
2 Reads
2.866 Impact Factor

A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.

Int J Geriatr Psychiatry 2019 Jan 31. Epub 2019 Jan 31.

Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD, USA.

Objective: While a number of single nucleotide polymorphisms (SNPs) associated with Alzheimer's disease (AD) or cognitive impairment have been identified, independent replications remain the only way to validate proposed signals. We investigated SNPs in candidate genes associated with either cognitive impairment or AD pathogenesis and their relationships with probable dementia (PD) in the Women's Health Initiative Memory Study (WHIMS).

Methods: We analyzed 96 SNPs across five genes (APOE/TOMM40, BDNF, COMT, SORL1, and KIBRA) in 2857 women (ages ≥65) from the WHIMS randomized trials of hormone therapy using a custom Illumina GoldenGate assay; 19% of the sample were MCI (N = 165) or PD (N = 387), and the remaining 81% were free of cognitive impairment. Read More

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http://dx.doi.org/10.1002/gps.5068DOI Listing
January 2019
2.866 Impact Factor

Psychosis symptoms in nursing home residents with and without dementia-Cross-sectional analyses from the COSMOS study.

Int J Geriatr Psychiatry 2019 Jan 31. Epub 2019 Jan 31.

Department of Global Public Health and Primary Care, Centre for Elderly and Nursing Home Medicine, University of Bergen, Bergen, Norway.

Objective: To investigate the characteristics of nursing home residents with psychosis and the association with potential underlying factors, such as pain, sleep disturbances, and antipsychotic medication.

Method: Five hundred forty-five residents with and without dementia from 67 Norwegian nursing home units were included in the cross-sectional analyses. Psychosis was the main outcome measure in our study; other outcome measures include quality of life (QoL), activities of daily living (ADL) function, cognitive function, pain, and antipsychotic medication. Read More

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http://dx.doi.org/10.1002/gps.5067DOI Listing
January 2019
1 Read

Social networks and loneliness in people with Alzheimer's dementia.

Int J Geriatr Psychiatry 2019 Jan 31. Epub 2019 Jan 31.

Brighton and Sussex Medical School, Brighton, UK.

Objectives: Modifiable lifestyle risk factors are of great interest in the prevention and management of Alzheimer's disease (AD). Loneliness and social networks may influence onset of AD, but little is known about this relationship in people with AD. The current study aimed to explore the relationship between loneliness and social networks (social measures) and cognitive and psychopathology decline (AD outcomes) in people with AD. Read More

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http://dx.doi.org/10.1002/gps.5065DOI Listing
January 2019

What influences the sustainability of an effective psychosocial intervention for people with dementia living in care homes? A 9 to 12-month follow-up of the perceptions of staff in care homes involved in the WHELD randomised controlled trail.

Int J Geriatr Psychiatry 2019 Jan 31. Epub 2019 Jan 31.

Center for Age-Related Medicine (SESAM), Stavanger University Hospital, Stavanger, Norway.

Objectives The study aims to understand the factors that care home staff felt enabled or hindered them in continuing to use the well-being and health for people with dementia (WHELD) psychosocial approach in their care home and investigate whether there was sustained activity 9 to 12 months after the study ended.

Methods: This qualitative study is part of a wider clinical trial, which demonstrated effectiveness of a psychosocial intervention on quality of life outcomes and neuropsychiatric symptoms for residents. Forty-seven care home staff within nine care homes in the United Kingdom participated in focus groups, between 9 and 12 months after the intervention had finished. Read More

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http://dx.doi.org/10.1002/gps.5066DOI Listing
January 2019

Acceptability and feasibility of wearing activity monitors in community-dwelling older adults with dementia.

Int J Geriatr Psychiatry 2019 Apr 20;34(4):617-624. Epub 2019 Feb 20.

Trafford Centre, Brighton and Sussex Medical School, University of Sussex, Brighton, UK.

Objectives: Measuring physical activity is complicated particularly in people with dementia, where activity levels are low and subjective measures are susceptible to inaccurate recall. Activity monitors are increasingly being used within research; however, it is unclear how people with dementia view wearing such devices and what aspects of the device effect wear time. The aim of the study was to evaluate the acceptability and feasibility of people with dementia wearing activity monitors. Read More

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http://dx.doi.org/10.1002/gps.5064DOI Listing

Effectiveness of DementiAbility Methods: The Montessori Way on agitation in long-term care home residents with dementia in Hong Kong.

Int J Geriatr Psychiatry 2019 Jan 29. Epub 2019 Jan 29.

Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.

Objective: To investigate the effect of the DementiAbility Methods: The Montessori Way (DMMW) on agitation in long-term care home residents with dementia. The activities using the DMMW are hypothesized to reduce agitation in terms of its frequency and disruptiveness to greater extent than structured social activities as control.

Methods: Forty-six long-term care home residents with dementia were randomly allocated to receive the DMMW (n = 23) or structured social activities as control (n = 23). Read More

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http://dx.doi.org/10.1002/gps.5063DOI Listing
January 2019

Ethnic differences in cognition and age in people diagnosed with dementia: A study of electronic health records in two large mental healthcare providers.

Int J Geriatr Psychiatry 2019 Mar 24;34(3):504-510. Epub 2019 Jan 24.

UCL Division of Psychiatry, London, UK.

Objectives: Qualitative studies suggest that people from UK minority ethnic groups with dementia access health services later in the illness than white UK-born elders, but there are no large quantitative studies investigating this. We aimed to investigate interethnic differences in cognitive scores and age at dementia diagnosis.

Methods: We used the Clinical Record Interactive Search (CRIS) applied to the electronic health records of two London mental health trusts to identify patients diagnosed with dementia between 2008 and 2016. Read More

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http://dx.doi.org/10.1002/gps.5046DOI Listing

The impact of apathy on cognitive performance in the elderly.

Int J Geriatr Psychiatry 2019 Jan 22. Epub 2019 Jan 22.

Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Bilbao, Spain.

Objectives: To examine the impact of apathy on cognitive performance in the elderly following the conceptual principles proposed by Marin and Stuss et al and to determine the role of the symptoms of apathy in different cognitive domains.

Methods: Cross-sectional study with a cohort of healthy elderly subjects over 55 years old (n = 140). One hundred forty healthy-elderly subjects (aged 79. Read More

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http://dx.doi.org/10.1002/gps.5062DOI Listing
January 2019

Associations between handgrip strength and mild cognitive impairment in middle-aged and older adults in six low- and middle-income countries.

Int J Geriatr Psychiatry 2019 Apr 17;34(4):609-616. Epub 2019 Feb 17.

The Cambridge Centre for Sport and Exercise Sciences, Department of Life Sciences, Anglia Ruskin University, Cambridge, UK.

Objectives: A number of small-scale, single-country studies have suggested that muscular weakness may be a biomarker for cognitive health, mild cognitive impairment (MCI), and dementia. However, multinational, representative studies are lacking, particularly from low- and middle-income countries (LMICs). Thus, we assessed the association between muscular strength (measured by maximal handgrip) and MCI in six LMICs (China, Ghana, India, Mexico, Russia, and South Africa), using nationally representative data. Read More

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http://dx.doi.org/10.1002/gps.5061DOI Listing
April 2019
3 Reads
2.866 Impact Factor

Benzodiazepines or related drugs and risk of pneumonia: A systematic review and meta-analysis.

Int J Geriatr Psychiatry 2019 Apr 8;34(4):513-521. Epub 2019 Jan 8.

Department of Psychiatry, The Seventh Hospital of Hangzhou, Hangzhou, China.

Objective: Benzodiazepines and benzodiazepine-related drugs (BZRDs) are used to treat various psychiatric diseases. However, there are concerns that BZRDs increase the risk of pneumonia.

Methods: We performed a systematic review and meta-analysis of observational studies to determine whether BZRD use affects the risk of pneumonia. Read More

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http://dx.doi.org/10.1002/gps.5048DOI Listing
April 2019
1 Read
2.866 Impact Factor

Evidence for underuse and overuse of antidepressants in older adults: Results of a large population-based study.

Int J Geriatr Psychiatry 2019 Apr 8;34(4):539-547. Epub 2019 Jan 8.

Department of General Internal Medicine and Psychosomatics, Medical University Hospital Heidelberg, Heidelberg, Germany.

Objectives: Depression is common among elderly people. However, diagnosis and adequate treatment is frequently difficult. Research on underuse and overuse of antidepressants in elderly persons is scarce. Read More

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http://dx.doi.org/10.1002/gps.5047DOI Listing
April 2019
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Anxiety symptom levels are persistent in older adults with a mental disorder: A 33-month follow-up study.

Int J Geriatr Psychiatry 2019 Apr 22;34(4):601-608. Epub 2019 Jan 22.

Department of Geriatric Psychiatry, Diakonhjemmet Hospital, Oslo, Norway.

Objective: Anxiety symptoms are common in old age and have been suggested as risk factors for development of cognitive impairment and mortality. The objective of the present study was to investigate whether anxiety symptoms among older adults with a mental health diagnosis are persistent, and severity of anxiety predicts cognitive decline and mortality.

Methods: We collected data from 201 patients referred to specialist mental health service in a department of geriatric psychiatry. Read More

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http://dx.doi.org/10.1002/gps.5058DOI Listing
April 2019
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Pharmacological basis for sedative and hypnotic like effects of Pyrus pashia using in vivo experimental models.

Int J Geriatr Psychiatry 2019 Jan 4. Epub 2019 Jan 4.

Department of Pharmacy, Abdul Wali Khan University, Mardan, Pakistan.

Objective: Pyrus pashia has traditionally been used as a therapeutic agent including sedative. In this regard, hydroethanolic extract of Pyrus pashia (HEPP) was screened for phytochemical investigation, acute toxicity, and sedative-hypnotic activity to provide a scientific rationale to its ethno-medicinal uses.

Methods: Mice were used in acute toxicity test; sedative potential was observed in open field test while thiopental-induced sleeping time and barbiturate-induced sleeping time tests were used for the assessment of hypnotic like effects of HEPP. Read More

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http://doi.wiley.com/10.1002/gps.5059
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http://dx.doi.org/10.1002/gps.5059DOI Listing
January 2019
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Carer insights into self-harm in the very old: A qualitative study.

Int J Geriatr Psychiatry 2019 Apr 14;34(4):594-600. Epub 2019 Jan 14.

Academic Department of Aged Care Psychiatry, Prince of Wales Hospital, Sydney, New South Wales, Australia.

Objective: To examine the insights of carers to better understand self-harm in their older relatives.

Methods: An in-depth interview was conducted with the nominated relative/friend (carer) of a person over 80 who had self-harmed within the last month. Carer interpretation and experience of the self-harm and clinical care were explored qualitatively. Read More

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http://dx.doi.org/10.1002/gps.5057DOI Listing
April 2019
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Verbal fluency in a national sample: Telephone administration methods.

Int J Geriatr Psychiatry 2019 Apr 18;34(4):578-587. Epub 2019 Jan 18.

Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.

Objectives: Describe novel methods for ascertaining verbal fluency in a large national sample of adults, examine demographic factors influencing performance, and compare scores to studies using in-person assessment.

Methods/design: Participants were from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, a national, population-based, longitudinal study of stroke in adults aged 45 years and older. Letter and semantic fluency were gathered, using Letter "F" and Animal Naming, via a telephone-based assessment with computer-assisted scoring of digital recordings. Read More

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http://doi.wiley.com/10.1002/gps.5054
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http://dx.doi.org/10.1002/gps.5054DOI Listing
April 2019
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Feasibility and utility of a cognitive screening for risk stratification in hospitalized older patients.

Int J Geriatr Psychiatry 2019 Apr 18;34(4):588-593. Epub 2019 Jan 18.

Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany.

Objectives: To determine whether the Mini-Cog can be applied by nursing staff to hospitalized elderly patients for cognitive impairment associated risk stratification.

Methods: This explorative prospective multicenter cohort study was carried out among 2522 patients aged 70 and older, hospitalized due to physical illness in eight hospitals in Rhineland-Palatinate, Germany. All patients were asked to conduct the Mini-Cog at the day of admission and were clustered into low-performance, intermediate-performance, and good-performance categories by trained nursing staff and two experienced geronto-psychiatrists as gold standard. Read More

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http://dx.doi.org/10.1002/gps.5056DOI Listing
April 2019
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Neurocognitive and psychiatric comorbidities of posttraumatic stress disorder among older veterans: A systematic review.

Int J Geriatr Psychiatry 2019 Apr 9;34(4):522-538. Epub 2019 Jan 9.

School of Nursing, Duke University, Durham, NC, USA.

Objectives: Posttraumatic stress disorder (PTSD) is associated with neurocognitive and psychiatric comorbidities, and older adults experience comorbid illnesses disproportionately. Little is known about the comorbidities of PTSD among older veterans. This systematic review examines the prevalence, incidence, and patterns of neurocognitive and psychiatric comorbidities of PTSD among older veterans and explores the factors associated with these comorbidities. Read More

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http://dx.doi.org/10.1002/gps.5055DOI Listing
April 2019
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Caregiver burden and quality of life two years after attendance at a memory clinic.

Int J Geriatr Psychiatry 2018 Dec 17. Epub 2018 Dec 17.

Department of Health Services Research & Policy, London School of Hygiene & Tropical Medicine, London, UK.

Objectives: We aimed to describe 1) the burden and HRQL of informal caregivers of new patients attending a memory assessment service (MAS), 2) changes in these outcomes over two years and 3) satisfaction with services.

Methods: Informal caregivers of patients attending one of 73 MASs throughout England completed questionnaires at the patient's first appointment, and 6 and 12 months later. Participants from 30 of these MASs were also followed up at 24 months. Read More

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http://doi.wiley.com/10.1002/gps.5053
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http://dx.doi.org/10.1002/gps.5053DOI Listing
December 2018
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Finding fault: Criticism as a care management strategy and its impact on outcomes for dementia caregivers.

Int J Geriatr Psychiatry 2019 Apr 3;34(4):571-577. Epub 2019 Jan 3.

Dean and Distinguished University Professor, College of Nursing and Health Professions, Drexel University, Philadelphia, Pennsylvania, USA.

Background: Despite a large literature on the stress process, little attention has focused on how caregivers for persons living with dementia (PLWDs) provide care and how this may impact care outcomes. Criticism is a management strategy caregivers may use to respond to behavioral symptoms. We consider whether criticism is associated with caregivers' mental health and service utilization. Read More

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http://dx.doi.org/10.1002/gps.5052DOI Listing
April 2019
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Health literacy, sociodemographic factors, and cognitive training in the active study of older adults.

Int J Geriatr Psychiatry 2019 Apr 14;34(4):563-570. Epub 2019 Jan 14.

Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA.

Objective: Health literacy is critical for understanding information from health-care providers and correct use of medications and includes the capacity to filter other information in navigating health care systems. Older adults with low health literacy exhibit more chronic health conditions, worse physical functioning, and poorer mental health. This study examined the relationship between sociodemographic variables and health literacy, and the impact of cognitive training on change in health literacy over 10 years in older adults. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/gps.5051
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http://dx.doi.org/10.1002/gps.5051DOI Listing
April 2019
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Dissociation in awareness of memory and language decline in Alzheimer's disease.

Int J Geriatr Psychiatry 2019 Apr 21;34(4):548-554. Epub 2018 Dec 21.

Center for Memory and Attention Disorders, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Objectives: The aim of this study was to examine awareness of decline in memory and in language in individuals with Alzheimer's disease (AD), by comparing participant and informant ratings, as well as these ratings and actual test performance.

Methods: We analyzed data from 149 individuals with AD enrolled in the Alzheimer's Disease Neuroimaging Initiative (ADNI) who filled the Everyday Cognition questionnaire and performed memory and language tasks.

Results: Participants provided significantly lower assessments of decline than did informants for both memory and language. Read More

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http://dx.doi.org/10.1002/gps.5049DOI Listing
April 2019
18 Reads

Are overweight people more susceptible to anxiety?

Int J Geriatr Psychiatry 2019 Apr 27;34(4):555-562. Epub 2018 Dec 27.

Center for Tobacco Control Research, Zhejiang University School of Medicine, Zhejiang, China.

Objectives: This study aimed to investigate anxiety status and its relationship with body mass index (BMI) among empty nesters in China, so as to improve their quality of life and provide direction for further research.

Methods: A cross-sectional survey was conducted among 4901 empty nesters in Shanxi, China. Anxiety, weight, height, depression, socio-demographic variables, attention to daily nutritional health, social activities, and self-care ability were evaluated in the study. Read More

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http://dx.doi.org/10.1002/gps.5050DOI Listing
April 2019
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