27,777 results match your criteria International journal of cardiology[Journal]


Sex-specific differences regarding seasonal variations of incidence and mortality in patients with myocardial infarction in Germany.

Int J Cardiol 2019 Apr 11. Epub 2019 Apr 11.

Department of Cardiology, Cardiology I, University Medical Center Mainz (Johannes Gutenberg-University Mainz), Mainz, Germany.

Background: Seasonal variation regarding the incidence and the short-term mortality of acute myocardial infarction (MI) was frequently reported, but data about sex-specific differences are sparse.

Methods: We analysed the impact of seasons and temperature on incidence and in-hospital mortality of patients with acute MI in Germany between 2005 and 2015.

Results: The nationwide sample comprised 3,008,188 hospitalizations of MI patients (2005-2015). Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.035DOI Listing

Risk of contrast-induced nephropathy in patients undergoing complex percutaneous coronary intervention.

Int J Cardiol 2019 Apr 14. Epub 2019 Apr 14.

Interventional Cardiology Division, Cardio-Thoracic-Vascular Department, San Raffaele Scientific Institute, Milan, Italy.

Background: Complex percutaneous coronary intervention (PCI) is associated with increased procedural challenges and high contrast load. We aimed to evaluate the association between complex PCI and contrast-induced nephropathy (CIN).

Methods: This single-center retrospective study included all-comers undergoing PCI between January 2012 and December 2016. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.043DOI Listing

Sugars make the difference - Glycosylation of cardiodepressant antibodies regulates their activity in dilated cardiomyopathy.

Int J Cardiol 2019 Apr 9. Epub 2019 Apr 9.

Department of Internal Medicine B, Cardiology, University Medicine Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Germany. Electronic address:

Background: Cardiodepressant antibodies contribute to cardiac dysfunction in dilated cardiomyopathy (DCM). Changes in immunoglobulin G (IgG) glycosylation modulate the activity of various autoimmune diseases and influence disease activity as well as severity of various autoimmune diseases. We hypothesized that alterations in IgG glycosylation are involved in the disease course of DCM. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.025DOI Listing

N-terminal pro-B-type natriuretic peptide in chronic heart failure: The impact of sex across the ejection fraction spectrum.

Int J Cardiol 2019 Apr 11. Epub 2019 Apr 11.

Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

Objective: The aim was to assess sex-specific differences in N-terminal B-type natriuretic peptide (NT-proBNP) regarding concentrations, predictors of high concentrations, and prognostic role, in a large and unselected population with chronic heart failure (HF) with preserved (HFpEF), mid-range (HFmrEF), and reduced ejection fraction (HFrEF).

Methods And Results: In 9847 outpatients with HFpEF, HFmrEF, and HFrEF (49 vs. 35 vs. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.023DOI Listing

Catheter based therapies in massive pulmonary embolism.

Int J Cardiol 2019 Apr 11. Epub 2019 Apr 11.

Division of Cardiovascular medicine, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1016/j.ijcard.2019.04.029DOI Listing

Plasma FABP4 levels are associated with left atrial fat volume in persistent atrial fibrillation and predict recurrence after catheter ablation.

Int J Cardiol 2019 Apr 10. Epub 2019 Apr 10.

Translational Cardiology Group, Health Research Institute of Santiago de Compostela, Spain; Cardiovascular area and Coronary Unit, University Clinical Hospital of Santiago de Compostela and Cardiology group of Health Research Institute, Spain; CIBERCV, Madrid, Spain. Electronic address:

Background: Imaging techniques have shown the association between left atrial adipose tissue (LAAT) volume and atrial fibrillation (AF) risk.

Purpose: To analyze 1) adipokines in peripheral and atrial plasma from patients undergoing AF ablation; 2) its association with LAAT volume measured by multislice CT and 3) its predictive value for AF recurrence.

Methods: Seventy consecutive patients undergoing AF catheter ablation were screened. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.031DOI Listing

Statin therapy for Takayasu Arteritis.

Int J Cardiol 2019 Apr 11. Epub 2019 Apr 11.

Ospedale San Raffaele, via Olgettina 60, 20132 Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2019.04.024DOI Listing

New-generation drug eluting stent vs. bare metal stent in saphenous vein graft - 1 year outcomes by a propensity score ascertainment (SVG Baltic Registry).

Int J Cardiol 2019 Apr 11. Epub 2019 Apr 11.

Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland.

Background: Data regarding the efficacy of the percutaneous coronary intervention (PCI) with new-designed drug-eluting stent (new-DES) vs. bare metal stent (BMS) of saphenous vein grafts (SVG) stenosis is scarce. The primary objective was to compare one-year clinical outcomes of PCI in stenosis of SVG using new-DES vs. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.022DOI Listing

Monocyte-platelet aggregates affect local inflammation in patients with acute myocardial infarction.

Int J Cardiol 2019 Apr 8. Epub 2019 Apr 8.

Klinik und Poliklinik für Innere Medizin I, Klinikum rechts der Isar, Technische Universität München, Munich, Germany. Electronic address:

The local inflammatory response following acute myocardial infarction (AMI) is increasingly being recognized as a central factor determining infarct healing. Myocardial inflammation can be visualized in patients using fasting F-FDG PET/MRI. Although this novel biosignal correlates with long-term functional outcome, the corresponding cellular substrate is not well understood. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.009DOI Listing

ST-segment elevation and cardiac magnetic resonance imaging findings in myocardial infarction with non-obstructive coronary arteries.

Int J Cardiol 2019 Apr 10. Epub 2019 Apr 10.

Soter Center for Women's Cardiovascular Research, Leon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, NY, United States of America. Electronic address:

Purpose: Patients with myocardial infarction and non-obstructive coronary arteries (MINOCA) may present with or without ST-elevation (STE) on the electrocardiogram (ECG). Previous studies have shown that STE was associated with higher risk of early mortality and long-term major adverse coronary events, and that cardiac magnetic resonance imaging (CMR) can help to determine whether the cause of a MINOCA presentation is ischemic or non-ischemic. We set out to determine the relationship between STE and CMR findings in patients presenting with MINOCA. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.028DOI Listing

Inflammation during acute coronary syndromes - Risk of cardiovascular events and bleeding.

Int J Cardiol 2019 Mar 27. Epub 2019 Mar 27.

Department of Cardiology, University Heart Center, University Hospital Zurich and University of Zurich, Zurich, Switzerland.

Background: Many parameters can affect the level of inflammation during acute coronary syndromes (ACS). We aimed to assess the one-year risk of major adverse cardiovascular events (MACE) and bleeding associated with elevated hsCRP levels during ACS, taking into account the severity of myocardial infarction, the timing of blood sampling and established long-term prognostic factors.

Methods: We studied 1864 consecutive patients with ACS enrolled in a contemporary multicenter prospective cohort study in Switzerland. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.03.049DOI Listing
March 2019
2 Reads

Right ventricular pressure overload alters cardiac lipid composition.

Int J Cardiol 2019 Apr 8. Epub 2019 Apr 8.

University of Groningen, University Medical Center Groningen, Center for Congenital Heart Diseases, Department of Pediatric Cardiology Groningen, the Netherlands.

Introduction: Right ventricular (RV) failure due to pressure load is an important determinant of clinical outcome in pulmonary hypertension, congenital heart disease and left ventricular failure. The last decades it has become clear that metabolic dysregulation is associated with the development of RV-failure. However, underlying mechanisms remain to be unraveled. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01675273183643
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http://dx.doi.org/10.1016/j.ijcard.2019.04.004DOI Listing
April 2019
1 Read

What would we find behind the darkness to predict patients' fate?

Int J Cardiol 2019 Apr 8. Epub 2019 Apr 8.

Cardiology Department, New Tokyo Hospital, Chiba, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2019.04.017DOI Listing

Serum potassium and glucose levels, and mortality in acute myocardial infarction; fact or myth?

Int J Cardiol 2019 Apr 8. Epub 2019 Apr 8.

Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S01675273193085
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http://dx.doi.org/10.1016/j.ijcard.2019.04.013DOI Listing
April 2019
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Valve in valve TAVI for degenerated Mitroflow is safe and feasible.

Int J Cardiol 2019 Apr 8. Epub 2019 Apr 8.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2019.04.016DOI Listing

Plasma endothelin-1 and adrenomedullin are associated with coronary artery function and cardiovascular outcomes in humans.

Int J Cardiol 2019 Apr 2. Epub 2019 Apr 2.

Department of Cardiology, Austin Health, Melbourne, Australia; Department of Medicine, Austin Health, The University of Melbourne, Melbourne, Australia.

Background: Endothelin-1 (ET-1) is a vasoconstrictor associated with cardiovascular disease, whereas adrenomedullin (ADM) is a vasorelaxant with cardioprotective properties. We sought to determine the relationship between plasma ET-1 and ADM with coronary circulatory function and long-term major adverse cardiovascular events (MACE).

Methods: Thirty-two patients undergoing coronary angiography for chest pain were recruited. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.008DOI Listing
April 2019
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Early invasive assessment of the coronary microcirculation predicts subsequent acute rejection after heart transplantation.

Int J Cardiol 2019 Apr 8. Epub 2019 Apr 8.

Division of Cardiovascular Medicine, Stanford Cardiovascular Institute, Stanford University School of Medicine, USA. Electronic address:

Background: Acute allograft rejection (AAR) plays an important role in patient and graft survival; therefore, more emphasis should be placed on its prediction. This study aimed to investigate baseline clinical and diagnostic variables associated with subsequent AAR during the first year post-transplant, especially focusing on early physiologic and anatomic measures.

Methods: This study enrolled 88 heart transplant patients who underwent fractional flow reserve (FFR), coronary flow reserve (CFR), the index of microcirculatory resistance (IMR) and intravascular ultrasound (IVUS) in the left anterior descending artery at baseline (within 8 weeks post-transplant). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01675273183680
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http://dx.doi.org/10.1016/j.ijcard.2019.04.018DOI Listing
April 2019
2 Reads

Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting using the human amniotic fluid stem cell secretome.

Int J Cardiol 2019 Apr 4. Epub 2019 Apr 4.

Regenerative Medicine Laboratory, Department of Experimental Medicine, University of Genova, Genova, Italy. Electronic address:

Background: The adult mammalian heart retains residual regenerative capability via endogenous cardiac progenitor cell (CPC) activation and cardiomyocyte proliferation. We previously reported the paracrine cardioprotective capacity of human amniotic fluid-derived stem cells (hAFS) following ischemia or cardiotoxicity. Here we analyse the potential of hAFS secretome fractions for cardiac regeneration and future clinical translation. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.011DOI Listing
April 2019
1 Read

Effect of stent diameter in women undergoing percutaneous coronary intervention with early- and new-generation drug-eluting stents: From the WIN-DES collaboration.

Int J Cardiol 2019 Mar 19. Epub 2019 Mar 19.

The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, USA. Electronic address:

Background: The risk of stent thrombosis (ST) or target lesion revascularization (TLR) is increased with smaller stent diameters (SD). Whether SD has a deleterious effect in women treated with early- vs. new-generation drug-eluting stents (DES) is unknown. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.03.034DOI Listing
March 2019
2 Reads
4.036 Impact Factor

Histopathological comparison of intramural coronary artery remodeling and myocardial fibrosis in obstructive versus end-stage hypertrophic cardiomyopathy.

Int J Cardiol 2019 Mar 28. Epub 2019 Mar 28.

Cardiovascular Pathology Unit, Department of Pathology, Sant'Orsola-Malpighi University Hospital, Bologna, Italy.

Background: Although imaging techniques have demonstrated the existence of microvascular abnormalities in hypertrophic cardiomyopathy (HCM), a detailed histopathological assessment is lacking as well as a comparison between different phases of the disease. We aimed to compare microvasculopathy and myocardial fibrosis in hypertrophic obstructive cardiomyopathy (HOCM) versus end-stage (ES) HCM.

Methods: 27 myectomy specimens of HOCM patients and 30 ES-HCM explanted hearts were analyzed. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.03.060DOI Listing
March 2019
2 Reads

Neuroinflammation as a mechanism for cardiovascular diseases.

Int J Cardiol 2019 Apr 4. Epub 2019 Apr 4.

Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273193117
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http://dx.doi.org/10.1016/j.ijcard.2019.04.003DOI Listing
April 2019
2 Reads

Propagation velocity at atrial fibrillation sources: Go with the flow.

Int J Cardiol 2019 Apr 3. Epub 2019 Apr 3.

Stanford University, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2019.04.007DOI Listing

The necessity of immediate cardio-thoracic surgical cover for high-risk transvenous lead extraction procedures: the Art of lead extraction.

Int J Cardiol 2019 Apr 3. Epub 2019 Apr 3.

Guy's & St Thomas' NHS Foundation Trust, London SE1 7EH, United Kingdom of Great Britain and Northern Ireland.

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http://dx.doi.org/10.1016/j.ijcard.2019.04.005DOI Listing

The impact of coronary sinus narrowing on diastolic function in patients with refractory angina.

Int J Cardiol 2019 Mar 21. Epub 2019 Mar 21.

Department of Cardiology, Tel Aviv Medical Center and Sackler School of Medicine, Tel Aviv University, Israel. Electronic address:

Objective: Evaluating the impact of Coronary sinus (CS) narrowing on diastolic function.

Background: Narrowing of the CS is an emerging therapy for refractory angina pectoris, improving perfusion to the ischemic subendocardium and relieving ischemia and angina. It was speculated that increased CS pressure might cause interstitial myocardial edema and diastolic dysfunction. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01675273183711
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http://dx.doi.org/10.1016/j.ijcard.2019.03.041DOI Listing
March 2019
2 Reads

The effect of ticagrelor based dual antiplatelet therapy on development of late left ventricular thrombus after acute anterior ST elevation myocardial infarction.

Int J Cardiol 2019 Apr 3. Epub 2019 Apr 3.

Department of Cardiology, Hisar Intercontinental Hospital, Istanbul, Turkey; Department of Biostatistics, Ataturk University Medical School, Erzurum, Turkey.

Aim: The aim of this study is to investigate the impact of ticagrelor as compared to clopidogrel based dual antiplatelet therapy (DAPT) during post-discharge management on the incidence of left ventricular (LV) thrombus in patients with first acute anterior ST elevation myocardial infarction (STEMI).

Method: 641 patients who met the inclusion criteria were divided into two groups based on the receipt of either ticagrelor or clopidogrel based DAPT.

Result: Left ventricular thrombus was detected in 73 (11. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.010DOI Listing

Non-specific chest pain and subsequent serious cardiovascular readmissions.

Int J Cardiol 2019 Apr 2. Epub 2019 Apr 2.

Keele Cardiovascular Research Group, Keele University, Stoke-on-Trent, UK; Royal Stoke University Hospital, Stoke-on-Trent, UK. Electronic address:

Background: The rates of readmission for serious cardiovascular events among patients admitted with a diagnosis of non-specific chest pain are unknown.

Methods: A national retrospective cohort study in the United States was undertaken to evaluate the rates, trends and predictors of readmission for serious cardiovascular events (acute coronary syndrome (ACS), pulmonary embolism (PE) and aortic dissection (AD)) after an inpatient episode with a primary diagnosis of non-specific chest pain.

Results: Among 1,172,430 patients with an index diagnosis of non-specific chest pain between 2010 and 2014, 2. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.001DOI Listing
April 2019
2 Reads

Left atrial volume quantification using coronary calcium score scan: Feasibility, reliability and reproducibility analysis of a standardized approach.

Int J Cardiol Heart Vasc 2019 Jun 30;23:100351. Epub 2019 Mar 30.

The Ohio State University Wexner Medical Center, 473 W 12th Avenue, Suite 200, Columbus, OH, 43210, United States of America.

Background: Left atrial volume (LAV) is an independent prognosticator of cardiovascular events. We investigated whether LAV could be accurately and reliably measured using coronary calcium score (CAC) scan.

Methods: We retrospectively selected consecutive patients that underwent coronary CT angiography (CCTA) and CAC scans. Read More

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http://dx.doi.org/10.1016/j.ijcha.2019.100351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441762PMC

Risks of age and sex on clinical outcomes post myocardial infarction.

Int J Cardiol Heart Vasc 2019 Jun 28;23:100350. Epub 2019 Mar 28.

Department of Cardiology, Chi Mei Medical Center, Tainan, Taiwan.

Background: How sex and age influence post-myocardial infarction (post-MI) outcomes remains unclear. This study evaluated the influence of sex and age on drug therapy, echocardiographic parameters, and outcomes in post-MI patients undergoing percutaneous coronary intervention (PCI).

Methods: We retrospectively enrolled 643 patients with first acute MI who underwent successful PCI and two echocardiographic examinations within 1 year after MI. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23529067183014
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http://dx.doi.org/10.1016/j.ijcha.2019.100350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441739PMC
June 2019
3 Reads

The use of a single chamber leadless pacemaker for the treatment of cardioinhibitory vasovagal syncope.

Int J Cardiol Heart Vasc 2019 Jun 28;23:100349. Epub 2019 Mar 28.

Manchester University NHS Foundation Trust, United Kingdom.

Background: The use of pacemakers in the treatment of cardioinhibitory vasovagal syncope is controversial with a mixed message from the limited evidence base. Single chamber leadless pacemakers have been shown to be an effective alternative option to conventional pacemakers.

Objective: This study examines the use of leadless pacemakers in a cardioinhibitory vasovagal population in the United Kingdom. Read More

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http://dx.doi.org/10.1016/j.ijcha.2019.100349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441741PMC
June 2019
1 Read

Association between resting heart rate, VOmax and carotid intima-media thickness in middle-aged men.

Int J Cardiol Heart Vasc 2019 Jun 29;23:100347. Epub 2019 Mar 29.

Department of Sports Medicine, National Fitness Center, Republic of Korea.

Introduction: Low resting heart rate (RHR) and high cardiorespiratory fitness (VOmax) are associated with a reduction in cardiovascular events (CV). Carotid intima-media thickness (CIMT) has been suggested as a predictor of CV. The purpose of this study was to investigate the association between RHR, VOmax and CIMT. Read More

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http://dx.doi.org/10.1016/j.ijcha.2019.100347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441756PMC

Reduction in thrombogenic activity and thrombocytopenia after transcatheter aortic valve implantation - The ATTRACTIVE-TTAS study.

Int J Cardiol Heart Vasc 2019 Jun 28;23:100346. Epub 2019 Mar 28.

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Introduction: Bleeding complications after transcatheter aortic valve implantation (TAVI) is a major problem in clinical practice. However, there is few information on thrombogenicity after TAVI. The aim of this study was to establish a monitoring of total thrombogenicity in perioperative TAVI using the Total Thrombus-formation Analysis System (T-TAS), a microchip-based flow chamber system for analysis of thrombus formation under flow condition. Read More

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http://dx.doi.org/10.1016/j.ijcha.2019.100346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441766PMC
June 2019
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Lack of IκBNS promotes cholate-containing high-fat diet-induced inflammation and atherogenesis in low-density lipoprotein (LDL) receptor-deficient mice.

Int J Cardiol Heart Vasc 2019 Jun 27;23:100344. Epub 2019 Mar 27.

Department of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Hongo, Tokyo, Japan.

Background: IκBNS, a nuclear IκB protein, regulates a subset of Toll-like receptor (TLR) dependent genes. A cholate-containing high-fat diet (HFD(CA(+))) induces TLR4 mediated early inflammatory response. The present study aims to clarify that the lack of IκBNS promotes atherogenesis in low-density lipoprotein receptor-deficient (LDLr) mice fed HFD(CA(+)) compared with those fed a cholate-free HFD (HFD(CA(-))). Read More

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http://dx.doi.org/10.1016/j.ijcha.2019.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439265PMC

Baseline LDL-C levels and risk of cardiovascular events: is there any room for questions?

Int J Cardiol 2019 Mar 29. Epub 2019 Mar 29.

Lipid Clinic Heart Institute (InCor)-University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil; Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

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http://dx.doi.org/10.1016/j.ijcard.2019.03.058DOI Listing

Exercise and heart. In medium virtus est?

Int J Cardiol 2019 Apr 3. Epub 2019 Apr 3.

Faculty of Sport Sciences, Universidad Europa de Madrid, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S01675273193136
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http://dx.doi.org/10.1016/j.ijcard.2019.04.002DOI Listing
April 2019
1 Read

Long-term outcomes with balloon-expandable and self-expandable prostheses in patients undergoing transfemoral transcatheter aortic valve implantation for severe aortic stenosis.

Int J Cardiol 2019 Mar 28. Epub 2019 Mar 28.

Department of Cardiology, Swiss Cardiovascular Center Bern, University Hospital, Bern, Switzerland.

Background: Data on long-term outcomes in patients undergoing transcatheter aortic valve implantation (TAVI) is scarce.

Methods: We investigated long term outcomes of consecutive patients undergoing TAVI with balloon- and self-expandable bioprostheses (Edwards SAPIEN (ESV), Edwards Lifesciences Inc., Irvine, CA, USA; Medtronic Corevalve system (MCS), Medtronic Inc. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.03.050DOI Listing
March 2019
1 Read

Daily risk of adverse outcomes in patients undergoing complex lesions revascularization: A subgroup analysis from the RAIN-CARDIOGROUP VII study (veRy thin stents for patients with left mAIn or bifurcatioN in real life).

Int J Cardiol 2019 Mar 22. Epub 2019 Mar 22.

Division of Cardiology, Departement of Internal Medicine, Città della Salute e della Scienza, Turin, Italy.

Introduction: Percutaneous coronary intervention (PCI) for complex lesions, including unprotected left main (ULM) and bifurcations, is gaining a relevant role in treating coronary artery disease with good outcomes, also thanks to new generation stents. The daily risk of adverse cardiovascular events and their temporal distribution after these procedures is not known.

Methods: All consecutive patients presenting with a critical lesion of ULM or bifurcation treated with very thin struts stents, enrolled in the RAIN-Cardiogroup VII study, were analyzed. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.03.038DOI Listing
March 2019
2 Reads
4.036 Impact Factor

Inhibition of circHIPK3 prevents angiotensin II-induced cardiac fibrosis by sponging miR-29b-3p.

Int J Cardiol 2019 Apr 2. Epub 2019 Apr 2.

Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200800, People's Republic of China. Electronic address:

Background: Circular RNAs (circRNAs) are emerging as powerful regulators of cardiac development and disease. Nevertheless, detailed studies describing circRNA-mediated regulation of cardiac fibroblasts (CFs) biology and their role in cardiac fibrosis remain limited.

Methods: PCR and Sanger sequencing were performed to identify the expression of circHIPK3 in CFs. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.006DOI Listing

In vitro mechanical behavior and in vivo healing response of a novel thin-strut ultrahigh molecular weight poly-l-lactic acid sirolimus-eluting bioresorbable coronary scaffold in normal swine.

Int J Cardiol 2019 Apr 4. Epub 2019 Apr 4.

CRF-Skirball Center for Innovation, Orangeburg, NY, United States of America; Cardiovascular Research Foundation, New York, NY, United States of America. Electronic address:

Background: New generation bioresorbable scaffolds (BRS) promise to improve the outcomes of current generation BRS technologies by decreasing wall thickness while maintaining structural strength. This study aimed to compare the biomechanical behavior and vascular healing profile of a novel thin-walled (98 μm) sirolimus-eluting ultrahigh molecular weight BRS (Magnitude, Amaranth Medical) to the Absorb everolimus-eluting bioresorbable vascular scaffold (Abbott Vascular).

Methods And Results: In vitro biomechanical testing showed lower number of fractures on accelerated cycle testing over time (at 21K cycles = 20. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01675273183503
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http://dx.doi.org/10.1016/j.ijcard.2019.04.012DOI Listing
April 2019
2 Reads
4.036 Impact Factor

Impact of moderate to severe mitral stenosis in patients undergoing transcatheter aortic valve replacement.

Int J Cardiol 2019 Mar 28. Epub 2019 Mar 28.

Quebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada. Electronic address:

Objective: In patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR), the impact of concomitant mitral stenosis (MS) remains unknown. The aim of this study was to determine the incidence and impact of moderate to severe MS in patients undergoing TAVR.

Methods: The study included 2113 consecutive patients (mean age: 80 ± 9 years, mean STS: 6. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.03.053DOI Listing
March 2019
1 Read

Cardiovascular disease, ABO locus, and markers of platelet functionality.

Authors:
Raha Pazoki

Int J Cardiol 2019 Mar 29. Epub 2019 Mar 29.

MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, St Mary's Campus, Norfolk Place, London W2 1PG, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273193053
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http://dx.doi.org/10.1016/j.ijcard.2019.03.061DOI Listing
March 2019
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Impact of atrial fibrillation in patients with lung cancer: Insights from National Inpatient Sample.

Int J Cardiol Heart Vasc 2019 Mar 12;22:216-217. Epub 2019 Mar 12.

Associate Director Cardiology, Clinical Operations Mount Sinai St. Luke's Hospital, NY, NY, USA.

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http://dx.doi.org/10.1016/j.ijcha.2019.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437280PMC

Bound to bleed: How altered albumin binding may dictate warfarin treatment outcome.

Int J Cardiol Heart Vasc 2019 Mar 25;22:214-215. Epub 2019 Mar 25.

Institute of Pharmacology, West German Heart and Vascular Center, University Duisburg-Essen, Germany.

Although non-vitamin-K anticoagulants are now the preferred option for stroke prevention in atrial fibrillation (AF), warfarin is still used in a significant number of patients. Warfarin dosing requirements are susceptible to drug interactions and genetic polymorphisms in metabolising enzymes. Human serum albumin (HSA) is a candidate modifier of warfarin pharmacokinetics, with hypoalbuminemia now shown to correlate with supratherapeutic INR levels and annual bleeding risk. Read More

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http://dx.doi.org/10.1016/j.ijcha.2019.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437285PMC
March 2019
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Atrial fibrillation in sub-Saharan Africa: The knowns and unknowns?

Int J Cardiol Heart Vasc 2019 Mar 11;22:212-213. Epub 2019 Mar 11.

Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia.

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http://dx.doi.org/10.1016/j.ijcha.2019.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437278PMC

Bayesian network analyses in atrial fibrillation - A path to better therapies?

Int J Cardiol Heart Vasc 2019 Mar 4;22:210-211. Epub 2019 Mar 4.

Institute of Pharmacology, West German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany.

Despite several major innovations in atrial fibrillation (AF) management, including the improved detection of AF and advances in catheter-ablation-based rhythm control, AF remains a major health-care burden. Recent advances have enabled curation of increasingly large data sets, which, together with improvements in AF detection through screening and continuous rhythm monitoring, enable novel 'big data' approaches to better predict and classify AF. In this issue of the , Drs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23529067193004
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http://dx.doi.org/10.1016/j.ijcha.2019.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437288PMC
March 2019
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A comprehensive clinical diagnostic score system for prediction of coronary artery spasm in patients with acute chest pain.

Int J Cardiol Heart Vasc 2019 Mar 23;22:205-209. Epub 2019 Feb 23.

Department of Cardiology, Shenzhen People's Hospital, 2nd Clinical Medical College of Jinan University, first affiliated Hospital of South University of Science and Technology, No. 1017, Dongmen Northern Road, 518020 Shenzhen, Guangdong, PR China.

Background: Currently, there is no validated multivariate model to predict probability of coronary artery spasm (CAS) in patients with acute chest pain.

Methods: A total of 976 consecutive patients with acute chest pain were enrolled. Patients were divided into two groups based on the presence of significant CAS. Read More

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http://dx.doi.org/10.1016/j.ijcha.2019.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437281PMC

Prevalence and risk factors for atrial fibrillation and its anticoagulant requirement in adults aged ≥40 in Jimma Town, Southwest Ethiopia: A community based cross-sectional study.

Int J Cardiol Heart Vasc 2019 Mar 23;22:199-204. Epub 2019 Feb 23.

Department of Medical Physiology, Faculty of Medical Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.

Background: There is no information on the prevalence and incidence of atrial fibrillation in Ethiopia. We aimed to investigate the prevalence, risk factors and anticoagulant requirements of atrial fibrillation in an elderly Jimma population.

Methods: In a community-based cross-sectional study in 634 adult (≥40 years) Jimma population, we performed cardiovascular health examinations including a 12-lead electrocardiogram to estimate AF prevalence. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23529067183016
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http://dx.doi.org/10.1016/j.ijcha.2019.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437289PMC
March 2019
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Impact of the clinical frailty scale on mid-term mortality in patients with ST-elevated myocardial infarction.

Int J Cardiol Heart Vasc 2019 Mar 11;22:192-198. Epub 2019 Mar 11.

Department of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.

Background: "Frailty" is associated with poor prognosis in ST-elevated myocardial infarction (STEMI). However, there is little data regarding the impact of the Canadian Study of Health and Aging Clinical Frailty Scale (CFS), a simple and semiquantitative tool for assessing frailty, on mid-term mortality in STEMI patients.

Methods: A total of 354 consecutive STEMI patients (mean age 69. Read More

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http://dx.doi.org/10.1016/j.ijcha.2019.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437299PMC

Increased level of high-sensitivity cardiac Troponin T in a geriatric population is determined by comorbidities compared to age.

Int J Cardiol Heart Vasc 2019 Mar 8;22:187-191. Epub 2019 Mar 8.

Department of Medicine, Division of Geriatrics, Faculty of Medicine, University of Sherbrooke, Canada.

High level of cardiac Troponin T (hs-cTnT) in geriatric population has been considered as an age-related phenomenon, which may question the interpretation of the increase of hs-cTnT in this population. The challenge is what is the primary cause of the increased hs-cTnT levels in elderly patients without AMI.

Objective: The aim of the current study was to determine the impact of aging on hs-cTnT levels in elderly patients without acute cardiac events but in the presence of comorbidities. Read More

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http://dx.doi.org/10.1016/j.ijcha.2019.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437284PMC