120 results match your criteria International forum of allergy & rhinology[Journal]


Effect of commercial nasal steroid preparation on bacterial growth.

Int Forum Allergy Rhinol 2019 Feb 12. Epub 2019 Feb 12.

Department of Otolaryngology-Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, University of Adelaide, Woodville South, SA, Australia.

Background: Topical budesonide (Pulmicort; AstraZeneca AB, Sodertalje, Sweden) is commonly used in the management of chronic rhinosinusitis (CRS). Although its use is due to its perceived anti-inflammatory effect, studies have suggested that it may also have antibacterial properties. To make the hydrophobic steroid molecule suitable for topical administration, pharmaceutical excipients are used in commercial steroid formulations. Read More

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http://dx.doi.org/10.1002/alr.22312DOI Listing
February 2019

The role of patient-reported outcomes in the management of chronic spontaneous urticaria.

Authors:
Kate Hopkinson

Br J Nurs 2019 Feb;28(3):144-150

Allergy Nurse Specialist, Department of Clinical Immunology and Allergy, Nottingham University Hospitals NHS Trust.

Chronic spontaneous urticaria (CSU) is a debilitating condition that can substantially affect patients' quality of life (QoL), mental health and ability to perform daily tasks. International guidelines on the management of CSU, jointly developed by the European Academy of Allergy and Clinical Immunology (EAACI), Global Allergy and Asthma European Network (GALEN), European Dermatology Forum (EDF) and World Allergy Organization (WAO), recommend a treat-to-target strategy until symptom control or remission is achieved. This may mean stepping up or down in the treatment algorithm according to the course of CSU and re-evaluating the need for continued/alternative drug treatment. Read More

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http://www.magonlinelibrary.com/doi/10.12968/bjon.2019.28.3.
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http://dx.doi.org/10.12968/bjon.2019.28.3.144DOI Listing
February 2019
2 Reads

The difference in nasal bacterial microbiome diversity between chronic rhinosinusitis patients with polyps and a control population.

Int Forum Allergy Rhinol 2019 Feb 5. Epub 2019 Feb 5.

Department of Otorhinolaryngology-Head and Neck Surgery, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, Sichuan, PR China.

Background: Little is known regarding the role of the microbiome of the paranasal sinuses and its contribution to sinus mucosal health and disease. Consequently, we examined the microbiome of chronic rhinosinusitis patients with polyps (CRSwNP) and a control population to provide new insights into the microbiota associated with the pathogenesis of CRSwNP.

Methods: Fifty-nine CRSwNP patients and 27 controls were enrolled in the study. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/alr.22297
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http://dx.doi.org/10.1002/alr.22297DOI Listing
February 2019
1 Read

Epidemiology and trends of anaphylaxis in the United States, 2004-2016.

Int Forum Allergy Rhinol 2019 Feb 4. Epub 2019 Feb 4.

Office of Biostatistics, Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, TX.

Background: No national study has examined the epidemiology of anaphylaxis after introduction of the codes of the International Statistical Classification of Diseases and Health Related Problems, Tenth Revision, Clinical Modification (ICD-10 CM). Our objective was to examine the trends in incidence and hospitalization rates in the United States utilizing ICD-9 and ICD-10 CM codes.

Methods: We used the Clinformatics database from 2004 to 2016. Read More

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http://dx.doi.org/10.1002/alr.22293DOI Listing
February 2019
1 Read

Clarithromycin for the treatment of adult chronic rhinosinusitis: a systematic review and meta-analysis.

Int Forum Allergy Rhinol 2019 Jan 10. Epub 2019 Jan 10.

Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.

Background: The aim of this systematic review (SR) was to assess the safety and efficacy of oral clarithromycin for the treatment of chronic rhinosinusitis (CRS).

Methods: This SR and meta-analysis was conducted based on the recommendations outlined in the Cochrane Handbook for SR of Interventions. The protocol was registered on PROSPERO, an international prospective register of SRs. Read More

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http://dx.doi.org/10.1002/alr.22281DOI Listing
January 2019
1 Read

ARIA pharmacy 2018 "Allergic rhinitis care pathways for community pharmacy".

Allergy 2018 Dec 18. Epub 2018 Dec 18.

MACVIA-France, Fondation partenariale FMC VIA-LR, Montpellier, France.

Pharmacists are trusted health professionals. Many patients use over-the-counter (OTC) medications and are seen by pharmacists who are the initial point of contact of allergic rhinitis management in most countries. The role of pharmacists in integrated care pathways (ICPs) for allergic diseases is important. Read More

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http://dx.doi.org/10.1111/all.13701DOI Listing
December 2018
8 Reads

Gastroesophageal reflux disease increases the risk of chronic rhinosinusitis: a nested case-control study using a national sample cohort.

Int Forum Allergy Rhinol 2018 Dec 10. Epub 2018 Dec 10.

Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University College of Medicine, Anyang, Korea.

Background: The purpose of this study was to evaluate the relations between gastroesophageal reflux disease (GERD) and chronic rhinosinusitus (CRS) in a Korean population.

Methods: Subjects from the Korean National Health Insurance Service-National Sample Cohort, all ≥20 years old, were assessed from 2002 to 2013. In total, 23,489 CRS participants were matched with 93,956 controls at a ratio of 1:4 with respect to age, group, sex, income group, region of residence, hypertension, diabetes, and dyslipidemia. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/alr.22259
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http://dx.doi.org/10.1002/alr.22259DOI Listing
December 2018
11 Reads

Air Pollution and Noncommunicable Diseases: A Review by the Forum of International Respiratory Societies' Environmental Committee, Part 2: Air Pollution and Organ Systems.

Chest 2019 Feb 9;155(2):417-426. Epub 2018 Nov 9.

School of Earth, Society, and Environment, Department of Atmospheric Sciences, University of Illinois, Urbana, IL.

Although air pollution is well known to be harmful to the lung and airways, it can also damage most other organ systems of the body. It is estimated that about 500,000 lung cancer deaths and 1.6 million COPD deaths can be attributed to air pollution, but air pollution may also account for 19% of all cardiovascular deaths and 21% of all stroke deaths. Read More

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http://dx.doi.org/10.1016/j.chest.2018.10.041DOI Listing
February 2019
16 Reads

Air Pollution and Noncommunicable Diseases: A Review by the Forum of International Respiratory Societies' Environmental Committee, Part 1: The Damaging Effects of Air Pollution.

Chest 2019 Feb 9;155(2):409-416. Epub 2018 Nov 9.

School of Earth, Society, and Environment, Department of Atmospheric Sciences, University of Illinois, Urbana, IL.

Air pollution poses a great environmental risk to health. Outdoor fine particulate matter (particulate matter with an aerodynamic diameter < 2.5 μm) exposure is the fifth leading risk factor for death in the world, accounting for 4. Read More

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http://dx.doi.org/10.1016/j.chest.2018.10.042DOI Listing
February 2019
15 Reads

ERS statement on harmonised standards for lung cancer registration and lung cancer services in Europe.

Eur Respir J 2018 Dec 20;52(6). Epub 2018 Dec 20.

Klinik für Pneumologie, Lungenklinik Heckeshorn, HELIOS Klinikum Emil von Behring, Berlin, Germany.

The European Respiratory Society (ERS) task force for harmonised standards for lung cancer registration and lung cancer services in Europe recognised the need to create a single dataset for use in pan-European data collection and a manual of standards for European lung cancer services.The multidisciplinary task force considered evidence from two different sources, reviewing existing national and international datasets alongside the results of a survey of clinical data collection on lung cancer in 35 European countries. A similar process was followed for the manual of lung cancer services, with the task force using existing guidelines and national or international recommendations for lung cancer services to develop a manual of standards for services in Europe. Read More

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http://dx.doi.org/10.1183/13993003.00610-2018DOI Listing
December 2018
3 Reads

Highlights of eosinophilic chronic rhinosinusitis with nasal polyps in definition, prognosis, and advancement.

Int Forum Allergy Rhinol 2018 Nov 8;8(11):1218-1225. Epub 2018 Oct 8.

Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, PR China.

Background: Tissue eosinophils are characteristic of inflammation in most but not all patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and may be useful for defining subgroups and making treatment choices. However, no consistent diagnostic criteria for CRSwNP with eosinophilic inflammation have been established.

Methods: Related literature review was performed and current developments in the diagnosis of eosinophilic CRSwNP were summarized. Read More

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http://doi.wiley.com/10.1002/alr.22214
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http://dx.doi.org/10.1002/alr.22214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282610PMC
November 2018
2 Reads

Management and outcome of epistaxis under direct oral anticoagulants: a comparison with warfarin.

Int Forum Allergy Rhinol 2019 Jan 3;9(1):120-124. Epub 2018 Oct 3.

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Munich, Munich, Germany.

Background: Epistaxis is one of the more common reasons for emergency room visits. The main risk factor for epistaxis is anticoagulant therapy. Until recently, the main culprit was oral intake of a vitamin K antagonist, such as warfarin, which has a number of side effects. Read More

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http://doi.wiley.com/10.1002/alr.22210
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http://dx.doi.org/10.1002/alr.22210DOI Listing
January 2019
9 Reads

International assessment of inter- and intrarater reliability of the International Frontal Sinus Anatomy Classification system.

Int Forum Allergy Rhinol 2019 Jan 14;9(1):39-45. Epub 2018 Sep 14.

Department of Otolaryngology-Head and Neck Surgery, University of Texas Health San Antonio, San Antonio, TX.

Background: Inconsistencies in the nomenclature of structures of the frontal sinus have impeded the development of a validated "reference standard" classification system that surgeons can reliably agree upon. The International Frontal Sinus Anatomy Classification (IFAC) system was developed as a consensus document, based on expert opinion, attempting to address this issue. The purposes of this study are to: establish the reliability of the IFAC as a tool for classifying cells in the frontal recess among an international group of rhinologists; and improve communication and teaching of frontal endoscopic sinus surgery (ESS). Read More

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http://doi.wiley.com/10.1002/alr.22200
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http://dx.doi.org/10.1002/alr.22200DOI Listing
January 2019
30 Reads

Proliferation and Contributions of National Database Studies in Otolaryngology Literature Published in the United States: 2005-2016.

Ann Otol Rhinol Laryngol 2018 Sep 26;127(9):643-648. Epub 2018 Jul 26.

1 Kansas University Medical Center, Kansas City, Kansas, USA.

Objective: Health registries and discharge-level databases are powerful tools. Commonly used data sets include the Nationwide Inpatient Sample (NIS); Surveillance, Epidemiology, and End Results Program (SEER); National Cancer Database (NCDB); and American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP). This study investigated the frequency with which these resources are being used and categorized their contributions to literature. Read More

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http://dx.doi.org/10.1177/0003489418784968DOI Listing
September 2018
1 Read

Sex bias in rhinology research.

Int Forum Allergy Rhinol 2018 Dec 20;8(12):1469-1475. Epub 2018 Jul 20.

Department of Otolaryngology-Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Background: Analysis of general surgery literature has revealed noteworthy sex bias and underreporting. Our objective was to determine the prevalence of sex bias and underreporting in rhinology.

Methods: All articles in 2016 issues of Rhinology, the American Journal of Rhinology and Allergy (AJRA), and the International Forum of Allergy and Rhinology (IFAR) were reviewed. Read More

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http://dx.doi.org/10.1002/alr.22179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279575PMC
December 2018
8 Reads

Quality indicators for the diagnosis and management of chronic rhinosinusitis.

Int Forum Allergy Rhinol 2018 Dec 12;8(12):1369-1379. Epub 2018 Jul 12.

Division of Rhinology, Department of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, ON, Canada.

Background: Chronic rhinosinusitis (CRS) has been identified as a high-priority disease category for quality improvement. To this end, this study aimed to develop CRS-specific quality indicators (QIs) to evaluate diagnosis and management that relieves patient discomfort, improves quality of life, and prevents complications.

Methods: A guideline-based approach, proposed in 2012 by Kötter et al. Read More

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http://dx.doi.org/10.1002/alr.22161DOI Listing
December 2018
24 Reads

A Comparison of the United States and International Perspective on Chronic Urticaria Guidelines.

J Allergy Clin Immunol Pract 2018 Jul - Aug;6(4):1144-1151. Epub 2018 May 18.

University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address:

Urticaria is a heterogeneous skin disorder that may be acute or chronic and is defined by the appearance of wheals, angioedema, or both. The European perspective is expressed in a recent international guideline and the American perspective has been based on the US Joint Task Force chronic urticaria practice parameter published in 2014. Both the international guideline (initiated by the European societies European Academy of Allergology and Clinical Immunology [EAACI]/Global Allergy and Asthma European Network [GALEN]/European Dermatology Forum [EDF] in collaboration with the World Allergy Organization [WAO]) and the US (American Academy of Allergy, Asthma & Immunology/American College of Allergy, Asthma and Immunology) guideline have been developed to help direct primary care physicians and specialists in the management of their patients with urticaria. Read More

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http://dx.doi.org/10.1016/j.jaip.2018.04.012DOI Listing
May 2018
3 Reads

Adult acute rhinosinusitis guidelines worldwide: similarities and disparities.

Int Forum Allergy Rhinol 2018 May 2. Epub 2018 May 2.

Department of Otolaryngology-Head and Neck Surgery, Assuta University Hospital, Faculty of Health Sciences, Ben Gurion University of the Negev, Ashdod, Israel.

Background: Acute rhinosinusitis (ARS) is a common respiratory infection that poses a major public healthcare burden with respect to antibiotic consumption and related morbidity. Position statements and national ARS guidelines have been published worldwide, aiming to define diagnostic criteria and outline treatment options. Our objective was to analyze the similarities and disparities between such guidelines. Read More

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http://doi.wiley.com/10.1002/alr.22125
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http://dx.doi.org/10.1002/alr.22125DOI Listing
May 2018
6 Reads
2.370 Impact Factor

mySinusitisCoach: patient empowerment in chronic rhinosinusitis using mobile technology.

Rhinology 2018 Sep;56(3):209-215

European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA), Brussels, Belgium.

Mobile health technology is emerging to take a prominent position in the management of chronic diseases. These technologies aim at enhancing patient empowerment via education and self-management. To date, of all the different apps available for patients with sinus disease, none were developed by medical experts dealing with chronic rhinosinusitis (CRS). Read More

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http://dx.doi.org/10.4193/Rhin17.253DOI Listing
September 2018
2 Reads

Computed tomography analysis of frontal cell prevalence according to the International Frontal Sinus Anatomy Classification.

Int Forum Allergy Rhinol 2018 07 19;8(7):825-830. Epub 2018 Feb 19.

Department of Otolaryngology-Head & Neck Surgery, Stanford University School of Medicine, Stanford, CA.

Background: The International Frontal Sinus Anatomy Classification (IFAC) is an international consensus document published in 2016 to standardize the nomenclature of cells in the region of the frontal recess and frontal sinus. The IFAC was designed to be surgically relevant and anatomically precise. The current study was undertaken to assess the prevalence of the frontal cell variants as defined by the IFAC, as well as to determine the interrater reliability of the IFAC. Read More

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http://dx.doi.org/10.1002/alr.22105DOI Listing
July 2018
4 Reads

International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis.

Int Forum Allergy Rhinol 2018 02;8(2):108-352

Otolaryngology, University of Michigan, USA.

Background: Critical examination of the quality and validity of available allergic rhinitis (AR) literature is necessary to improve understanding and to appropriately translate this knowledge to clinical care of the AR patient. To evaluate the existing AR literature, international multidisciplinary experts with an interest in AR have produced the International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR).

Methods: Using previously described methodology, specific topics were developed relating to AR. Read More

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http://dx.doi.org/10.1002/alr.22073DOI Listing
February 2018
74 Reads
4 Citations
2.371 Impact Factor

International consensus statement on allergy and rhinology: allergic rhinitis-executive summary.

Int Forum Allergy Rhinol 2018 02;8(2):85-107

Department of Otolaryngology-Head and Neck Surgery, Temple University, Philadelphia, PA.

Background: The available allergic rhinitis (AR) literature continues to grow. Critical evaluation and understanding of this literature is important to appropriately utilize this knowledge in the care of AR patients. The International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR) has been produced as a multidisciplinary international effort. Read More

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http://dx.doi.org/10.1002/alr.22070DOI Listing
February 2018
9 Reads

Open Access: Is There a Predator at the Door?

Otol Neurotol 2018 Mar;39(3):271-272

Co-Editor-in-Chief, American Journal of Rhinology & Allergy Senior Editor, Journal of Laryngology and Otology Editor-in-Chief, Clinical Otolaryngology Editor-in-Chief, International Forum of Allergy & Rhinology Co-Editor-in-Chief, Journal of Neurological Surgery-Part B Editor-in-Chief, Otolaryngology-Head and Neck Surgery, Editor-in-Chief, OTO-Open Co-Editor-in-Chief, Journal of Neurological Surgery-Part B Editor-in-Chief, Otology & Neurotology Editor-in-Chief, Journal for Oto-Rhino-Laryngology, Head and Neck Surgery Editor-in-Chief, JAMA Otolaryngology-Head & Neck Surgery Editor-in-Chief, International Journal of Pediatric Otorhinolaryngology Editor-in-Chief, Journal of Voice; Editor-in-Chief, Ear, Nose and Throat Journal ORL - Head and Neck Nursing Co-Editor-in-Chief, American Journal of Rhinology & Allergy Editor-in-Chief, Annals of Otology, Rhinology & Laryngology Editor-in-Chief, The Laryngoscope Editor-in-Chief, American Journal of Otolaryngology Editor-in-Chief, Laryngoscope Investigative Otolaryngology Senior Editor, Journal of Laryngology and Otology.

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http://dx.doi.org/10.1097/MAO.0000000000001721DOI Listing
March 2018
11 Reads

Meeting report: Global vaccine and immunization research forum.

Vaccine 2018 02 12;36(7):915-920. Epub 2018 Jan 12.

Department of Immunization, Vaccines, and Biologicals, World Health Organization (WHO), Geneva, Switzerland.

Building on the success of the first Global Vaccine and Immunization Research Forum (GVIRF), the World Health Organization, the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health in the United States of America, and the Bill & Melinda Gates Foundation convened the second GVIRF in March 2016. Leading scientists, vaccine developers, and public health officials from around the world discussed scientific advances and innovative technologies to design and deliver vaccines as well as novel tools and approaches to increase the uptake of vaccines throughout the world. This report summarizes the discussions and conclusions from the forum participants. Read More

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http://dx.doi.org/10.1016/j.vaccine.2017.12.013DOI Listing
February 2018
3 Reads

The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria.

Allergy 2018 Jul;73(7):1393-1414

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology and Allergy, Allergy-Centre-Charité, Berlin, Germany.

This evidence- and consensus-based guideline was developed following the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. The conference was held on 1 December 2016. It is a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), the EU-founded network of excellence, the Global Allergy and Asthma European Network (GA²LEN), the European Dermatology Forum (EDF) and the World Allergy Organization (WAO) with the participation of 48 delegates of 42 national and international societies. Read More

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http://dx.doi.org/10.1111/all.13397DOI Listing
July 2018
73 Reads

Comparison of the Outcomes of Individuals With Medically Attended Influenza A and B Virus Infections Enrolled in 2 International Cohort Studies Over a 6-Year Period: 2009-2015.

Open Forum Infect Dis 2017 7;4(4):ofx212. Epub 2017 Oct 7.

Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota.

Background: Outcome data from prospective follow-up studies comparing infections with different influenza virus types/subtypes are limited.

Methods: Demographic, clinical characteristics and follow-up outcomes for adults with laboratory-confirmed influenza A(H1N1)pdm09, A(H3N2), or B virus infections were compared in 2 prospective cohorts enrolled globally from 2009 through 2015. Logistic regression was used to compare outcomes among influenza virus type/subtypes. Read More

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http://dx.doi.org/10.1093/ofid/ofx212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740982PMC
October 2017
9 Reads

Risks of Ruxolitinib in Gain-of-Function-Associated Severe Fungal Disease.

Open Forum Infect Dis 2017 22;4(4):ofx202. Epub 2017 Sep 22.

Immunopathogenesis Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Immunology, National Institutes of Health, Bethesda, Maryland.

Heterozygous gain-of-function (GOF) mutations are associated with chronic mucocutaneous candidiasis and a broad spectrum of infectious, inflammatory, and vascular manifestations. We describe therapeutic failures with the Janus Kinase (JAK) inhibitor ruxolitinib in 2 GOF patients with severe invasive or cutaneous fungal infections. Read More

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https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofx20
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http://dx.doi.org/10.1093/ofid/ofx202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714179PMC
September 2017
23 Reads

Rhinology Future Debates, an EUFOREA Report.

Rhinology 2017 Dec;55(4):298-304

Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands and Department of Otorhinolaryngology, University Hospitals Leuven, Belgium.

The first Rhinology Future Debates was held in Brussels in December 2016, organized by EUFOREA (European Forum for Research and Education in Allergy and Airways diseases). The purpose of these debates is to bring novel developments in the field of Rhinology to the attention of the medical, paramedical and patient community, in a highly credible and balanced context. For the first time in Rhinology, a peer to peer scientific exchange with key experts in the field of rhinology and key medical colleagues from leading industries let to a brainstorming and discussion event on a number of hot issues in Rhinology. Read More

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http://dx.doi.org/10.4193/Rhin17.221DOI Listing
December 2017
4 Reads

Therapeutic potential of α-lipoic acid derivative, sodium zinc histidine dithiooctanamide, in a mouse model of allergic rhinitis.

Int Forum Allergy Rhinol 2017 11 1;7(11):1095-1103. Epub 2017 Sep 1.

Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Background: Oxidative stress is involved in various diseases, including allergies. Several studies have pointed to the preventive and therapeutic potential of antioxidants in allergic disorders. However, little is known about the immunomodulatory effects of antioxidants in type I hypersensitivity. Read More

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http://dx.doi.org/10.1002/alr.22008DOI Listing
November 2017
13 Reads

Evaluation of a Guidelines-Based Approach to the Treatment of Chronic Spontaneous Urticaria.

J Allergy Clin Immunol Pract 2018 Jan - Feb;6(1):177-182.e1. Epub 2017 Jul 12.

Group of Experimental and Clinical Allergy, IPS Universitaria, University of Antioquia, Medellín, Colombia.

Background: International scientific associations have made recommendations for the management of chronic spontaneous urticaria (CSU) that have been summarized in clinical guidelines.

Objective: To evaluate the clinical impact of guideline recommendations for CSU management.

Methods: A multicenter, triple-blinded, prospective, randomized study (the Urticaria Research of Tropical Impact and Control Assessment project; ClinicalTrials. Read More

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http://dx.doi.org/10.1016/j.jaip.2017.06.002DOI Listing
July 2017
12 Reads

Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force.

Ann Rheum Dis 2018 01 6;77(1):3-17. Epub 2017 Jul 6.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

Therapeutic targets have been defined for axial and peripheral spondyloarthritis (SpA) in 2012, but the evidence for these recommendations was only of indirect nature. These recommendations were re-evaluated in light of new insights. Based on the results of a systematic literature review and expert opinion, a task force of rheumatologists, dermatologists, patients and a health professional developed an update of the 2012 recommendations. Read More

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http://dx.doi.org/10.1136/annrheumdis-2017-211734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754738PMC
January 2018
80 Reads

Medication-related costs of rhinitis in Australia: a NostraData cross-sectional study of pharmacy purchases.

J Asthma Allergy 2017 9;10:153-161. Epub 2017 May 9.

Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK.

Purpose: There is a relative paucity of research regarding medication expenditure associated with multiple-therapy use for rhinitis in Australia. To describe 1) the nature and extent of multiple-therapy use for rhinitis in Australia using data on therapies purchased with prescription or over-the-counter (OTC) and 2) additional costs incurred by multiple-therapy use compared with intranasal corticosteroid (INCS) therapy alone.

Patients And Methods: A retrospective observational study was carried out using a database containing anonymous pharmacy transaction data available from 20% of pharmacies in Australia that links doctor prescriptions and OTC purchase information. Read More

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http://dx.doi.org/10.2147/JAA.S128431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431691PMC
May 2017
46 Reads

Early postoperative management after lung transplantation: Results of an international survey.

Clin Transplant 2017 07 29;31(7). Epub 2017 May 29.

Advanced Lung Disease and Transplant Program, Inova Fairfax Hospital, Falls Church, VA, USA.

Introduction: Little data exist regarding optimal therapeutic strategies postoperatively after lung transplant (LTx). Current practice patterns rely on expert opinion and institutional experience resulting in nonuniform postoperative care. To better define current practice patterns, an international survey of LTx clinicians was conducted. Read More

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http://dx.doi.org/10.1111/ctr.12985DOI Listing
July 2017
3 Reads

The International Classification of the radiological Complexity (ICC) of frontal recess and frontal sinus.

Int Forum Allergy Rhinol 2017 04 5;7(4):332-337. Epub 2016 Dec 5.

Department of Surgery-Otolaryngology, University of Adelaide, Adelaide, Australia.

Background: The frontal sinus is considered the most challenging sinus to address surgically. There are no current classifications of the degree of surgical complexity of different frontal sinus configurations. The aim of this study is to develop a classification system of the degree of complexity of frontal recess surgery based on preoperative computed tomography (CT) scans. Read More

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http://dx.doi.org/10.1002/alr.21893DOI Listing
April 2017
19 Reads

Mitochondrial Haplogroups as a Risk Factor for Herpes Zoster.

Open Forum Infect Dis 2016 Oct 19;3(4):ofw184. Epub 2016 Oct 19.

Vanderbilt Genetics Institute; Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.

 Herpes zoster, or shingles, is a common, painful reactivation of latent varicella zoster virus infection. Understanding host factors that predispose to herpes zoster may permit development of more effective prevention strategies. Our objective was to examine mitochondrial haplogroups as a potential host factor related to herpes zoster incidence. Read More

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http://dx.doi.org/10.1093/ofid/ofw184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088697PMC
October 2016
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Factors impacting cerebrospinal fluid leak rates in endoscopic sellar surgery.

Int Forum Allergy Rhinol 2016 11 23;6(11):1117-1125. Epub 2016 Aug 23.

Department of Otolaryngology-Head & Neck Surgery, Medical University of South Carolina, Charleston, SC.

Background: In patients undergoing transnasal endoscopic sellar surgery, an analysis of risk factors and predictors of intraoperative and postoperative cerebrospinal fluid leak (CSF) would provide important prognostic information.

Methods: A retrospective review of patients undergoing endoscopic sellar surgery for pituitary adenomas or craniopharyngiomas between 2002 and 2014 at 7 international centers was performed. Demographic, comorbidity, and tumor characteristics were evaluated to determine the associations between intraoperative and postoperative CSF leaks. Read More

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http://dx.doi.org/10.1002/alr.21783DOI Listing
November 2016
14 Reads

Effectiveness of atorvastatin in suppressing MUC5AC gene expression in human airway epithelial cells.

Int Forum Allergy Rhinol 2016 11 16;6(11):1159-1166. Epub 2016 Jun 16.

Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea.

Background: We recently reported that chronic cholesterol depletion in NCI-H292 cells by lovastatin suppresses interleukin (IL)-1β-induced MUC5AC gene expression. However, as there are numerous statins affect MUC5AC expression, we sought to determine which statin is most effective in reducing MUC5AC expression, and whether this activity of statins is related to IL-1 receptor (IL-1RI) and mitogen-activated protein kinase (MAPK) activity.

Methods: Four statins, namely atorvastatin, fluvastatin, lovastatin, and simvastatin, were tested. Read More

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http://dx.doi.org/10.1002/alr.21811DOI Listing
November 2016
19 Reads

A validated case definition for chronic rhinosinusitis in administrative data: a Canadian perspective.

Int Forum Allergy Rhinol 2016 11 26;6(11):1167-1172. Epub 2016 May 26.

Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.

Background: Pharmacoepidemiological research using administrative databases has become increasingly popular for chronic rhinosinusitis (CRS); however, without a validated case definition the cohort evaluated may be inaccurate resulting in biased and incorrect outcomes. The objective of this study was to develop and validate a generalizable administrative database case definition for CRS using International Classification of Diseases, 9th edition (ICD-9)-coded claims.

Methods: A random sample of 100 patients with a guideline-based diagnosis of CRS and 100 control patients were selected and then linked to a Canadian physician claims database from March 31, 2010, to March 31, 2015. Read More

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http://dx.doi.org/10.1002/alr.21801DOI Listing
November 2016
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European consensus-based (S2k) Guideline on the Management of Herpes Zoster - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV), Part 1: Diagnosis.

J Eur Acad Dermatol Venereol 2017 Jan 2;31(1):9-19. Epub 2016 Nov 2.

Division of Evidence Based Medicine in Dermatology (dEBM), Department of Dermatology, Venereology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Herpes zoster (HZ, shingles) is a frequent medical condition which may severely impact the quality of life of affected patients. Different therapeutic approaches to treat acute HZ are available. The aim of this European project was the elaboration of a consensus-based guideline on the management of patients who present with HZ, considering different patient populations and different localizations. Read More

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http://dx.doi.org/10.1111/jdv.13995DOI Listing
January 2017
5 Reads

Successful repair of intraoperative cerebrospinal fluid leaks improves outcomes in endoscopic skull base surgery.

Int Forum Allergy Rhinol 2017 01 31;7(1):80-86. Epub 2016 Aug 31.

Department of Otolaryngology-Head & Neck Surgery, Medical University of South Carolina, Charleston, SC.

Background: The impact of failed cerebrospinal fluid leak (CSF) leak repair in endoscopic skull base surgery has not been adequately studied.

Methods: In this investigation we reviewed patients who had undergone endoscopic skull base surgery between 2002 and 2014 at 7 international centers. Demographic variables, comorbidities, tumor characteristics, and repair techniques were evaluated to determine association with successful repair of CSF leak. Read More

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http://dx.doi.org/10.1002/alr.21845DOI Listing
January 2017
17 Reads