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Int Ophthalmol 2019 Apr 13. Epub 2019 Apr 13.

Division of Ophthalmology, Sourasky Medical Center Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Purpose: To report and characterize cases of very late onset (5 years or more after surgery) flap margin corneal ulcers after laser in situ keratomileusis (LASIK) procedure.

Methods: A retrospective case series of consecutive patients who were diagnosed with very late flap margin corneal ulcers following LASIK, between January 2014 and July 2017. All patients were treated with topical antibiotics and were followed up until complete resolution. Read More

Int Ophthalmol 2019 Apr 11. Epub 2019 Apr 11.

Department of Pediatrics, Division of Nutrition and Metabolism, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.

Purpose: To evaluate accumulation patterns of deposits in retinal layers of type B Niemann-Pick patients by multimodal imaging.

Methods: Seven patients with type B Niemann-Pick disease were included in this study. All participants underwent a complete ophthalmologic evaluation, high-resolution digital colour imaging, spectral-domain optical coherence tomography, blue light fundus autofluorescence and optical coherence tomography angiography (OCTA). Read More

Int Ophthalmol 2019 Apr 11. Epub 2019 Apr 11.

Fernández-Vega Ophthalmological Institute, Avda. Dres. Fernández-Vega 114, 33012, Oviedo, Spain.

Purpose: To report visual and refractive results in radial keratotomy (RK) patients that underwent a cataract surgery with a monofocal intraocular lens (IOL) implantation with 1 year of follow-up.

Methods: Twenty-eight eyes of 15 patients with cataract and the previous RK were included. All eyes underwent phacoemulsification and monofocal IOL implantation. Read More

Int Ophthalmol 2019 Apr 10. Epub 2019 Apr 10.

Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.

Purpose: Retinitis pigmentosa (RP) is the most common hereditary retinal degeneration and an important cause of visual disability worldwide. Rhodopsin gene is one of the most important genes implicated in autosomal dominant RP (ADRP). In this study, we investigated rhodopsin gene mutations in Iranian patients with ADRP. Read More

Int Ophthalmol 2019 Apr 9. Epub 2019 Apr 9.

Ophthalmic Research Center, Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Boostan 9 St., Pasdaran Ave., Tehran, 16666, Iran.

Purpose: To determine the roundness of recipient corneal cuts after mechanical trephination and to investigate possible factors that could affect the corneal bed configuration in deep anterior lamellar keratoplasty (DALK).

Methods: This study enrolled 85 eyes with keratoconus that underwent DALK. Recipient corneas were partially trephined using a new, unused, disposable Hessburg-Barron suction trephine. Read More

Int Ophthalmol 2019 Apr 9. Epub 2019 Apr 9.

Eye Center, Medical Center, University Hospital Freiburg, University of Freiburg, Killianstrasse 5, 79106, Freiburg, Germany.

Purpose: Intraocular pressure (IOP) measurement can be performed with different methods. Newer methods have to be compared to the standard method, the Goldmann applanation tonometry (GAT). We herein compare two air-puff tonometers, the non-contact tonometer (Tomey NCT) and the Corvis ST (CST) with GAT in eyes with a broad spectrum of IOP. Read More

Int Ophthalmol 2019 Apr 20;39(4):957-970. Epub 2019 Mar 20.

Department of Ophthalmology, The Second Hospital of Jilin University, 218 Ziqiang Street, Changchun, 130041, Jilin, China.

Purpose: To review and summarize the recent progress in the diagnosis and treatment of Coats' disease.

Methods: Literature was collected from Web of Science, Medline and Pubmed, through searching of these keywords: "Coats' disease", "diagnosis" and "treatment".

Results: Coats' disease is characterized by idiopathic leaky retinal vascular telangiectasia and microvascular abnormalities often accompanied by intraretinal or subretinal exudation and retinal detachment. Read More

Int Ophthalmol 2019 Mar 15. Epub 2019 Mar 15.

Department of Opthalmology, Selcuk University Faculty of Medicine, Konya, Turkey.

Purpose: To evaluate the retinal vascular plexus and choriocapillaris structures in patients with non-ocular Behçet's disease (BD) using optical coherence tomography angiography (OCTA).

Methods: The study included 42 eyes of non-ocular BD patients (study group) and 40 eyes of 20 healthy subjects (control group). Flow area (mm), mean vascular density (VD) (%) and foveal avascular zone (FAZ) (mm) were measured using OCTA (Optovue Inc. Read More

Int Ophthalmol 2019 Mar 13. Epub 2019 Mar 13.

Department of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Novena, Singapore.

Fireworks are an integral aspect of national, cultural and religious festivals globally, featuring in a vast range of celebrations including Diwali in India and New Year's Eve in the USA. We have seen a trend in eye injuries related to the use of fireworks, with millions of people, of which a large proportion comprising children, are injured annually-and rather than falling, as one would hope, this number is remaining stable. A comprehensive study of the impact of firework-related injuries to the eye is not available, and the efforts to mitigate this are not widely discussed in the literature. Read More

Int Ophthalmol 2019 Mar 11. Epub 2019 Mar 11.

Ophthalmology Department, Faculty of Medicine, Benha University Hospitals, Benha University, Benha, Egypt.

Purpose: To evaluate circular neodymium: YAG laser incision in cases of anterior capsular contraction syndrome (ACCS) by comparing it to radial Neodymium: YAG laser incision as for efficacy and safety.

Settings: Ophthalmology Department, Benha University Hospitals.

Methods: The study was done on 74 eyes of 66 patients with symptomatic ACCS. Read More

Int Ophthalmol 2019 Mar 9. Epub 2019 Mar 9.

Department of Ophthalmology, Valencia University Clinic Hospital, Avenida Blasco Ibáñez, 17, 46010, Valencia, Spain.

Purpose: The authors report a case of Purtscher's retinopathy whose optical coherence tomography angiography (OCT-A) analysis allows us to better understand the vascular network of the optic disk.

Methods: Case report.

Results: A 75-year-old man presented with vision loss in his left eye (LE) after chest compression. Read More

Int Ophthalmol 2019 Mar 9. Epub 2019 Mar 9.

Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Stavros Niarchos Avenue, 45110, Ioannina, Greece.

Purpose: To evaluate the clinical manifestations of intraocular inflammation associated with Bartonella infection and describe the assessment and management of patients with cat-scratch disease (CSD).

Methods: This is a retrospective review of the clinical records of patients diagnosed with Bartonella henselae and Bartonella quintana intraocular inflammation from 2011 to 2018 in the Department of Ocular Inflammations and Infections of the University Eye Clinic of Ioannina (Greece). An analysis of the current literature concerning Bartonella-related intraocular infections was also carried out. Read More

Int Ophthalmol 2019 Mar 4. Epub 2019 Mar 4.

University Eye Hospital, University of Leipzig, Liebigstrasse 10-14, 04103, Leipzig, Germany.

Purpose: The aim was to compare the postsurgical outcomes of trabeculectomy (TET) and transscleral cyclophotocoagulation (CPC) in a similar cohort of eyes diagnosed with primary open-angle glaucoma (POAG).

Materials And Methods: For this monocentric non-randomized retrospective comparative trial, the records of eyes which underwent TET or CPC between 2013 and 2016 at our institution for the treatment of POAG were reviewed. Parameters analyzed before surgery as well as 1 and 2-3 years afterwards were visual acuity (VA), intraocular pressure (IOP), mean defect (MD) of the visual field, number of glaucoma medications and the objective refraction using which the surgically induced astigmatism (SIA) was calculated. Read More

Int Ophthalmol 2019 Mar 4. Epub 2019 Mar 4.

Birmingham and Midland Eye Centre, Birmingham, UK.

Purpose: To compare surgical parameters among eyes undergoing laser-assisted cataract surgery (LACS) using different lens fragmentation patterns (LFP).

Methods: Prospective, randomized, unmasked clinical trial. One-hundred eyes underwent LACS and were randomly assigned to 1 of 3 LFP treatment groups: (1) laser capsulotomy only; no lens fragmentation (NLF) (n = 34); (2) three-plane chop (TPC) (n = 33); and, (3) pie-cut pattern (PCP) fragmentation (n = 33). Read More

Int Ophthalmol 2019 Mar 4. Epub 2019 Mar 4.

Gazi Yaşargil Eğitim ve Araştırma Hastanesi, Diyarbakir, Turkey.

Objective: Evaluation of vascular leakage and retinal vascular development with fundus fluorescein angiography for infants diagnosed with aggressive posterior retinopathy of prematurity who underwent intravitreal anti-VEGF treatment.

Method: Medical recordings of 30 patients who received RetCam fluorescein angiography during follow-up and had been treated with anti-VEGF on diagnosis of aggressive posterior ROP in the zone I or zone II between the dates of April 2014-January 2017 were evaluated retrospectively.

Results: Fifty-nine eyes of 30 patients were included in the study. Read More

Int Ophthalmol 2019 Mar 2. Epub 2019 Mar 2.

Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, No 23, Paydarfard-9th Boostan St., Pasdaran Ave, Tehran, 1666673111, Iran.

Purpose: Currently, regenerative medicine has attracted much attention among researchers investigating new methods to treat ocular surface diseases. Based on this new concept, cultivated limbal epithelial transplantation (CLET), whether in the form of autograft or allograft, has emerged as a promising surgical procedure for treating limbal stem cell deficiency (LSCD). Given that there is no updated comparison between autograft and allograft CLETs, the present review and meta-analysis aims to compare and determine the efficacy of two different CLET techniques, autologous versus allogeneic, based on a literature review of relevant studies. Read More

Int Ophthalmol 2019 Mar 1. Epub 2019 Mar 1.

School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, 325000, China.

Purpose: To develop a new regression formula based on the Gaussian thick lens formula and to verify the accuracy of the regression formula.

Methods: In this prospective study, 207 eyes of 207 myopic subjects and 133 eyes of 67 postoperative subjects were included. For the 133 postoperative eyes, 127 eyes underwent laser-assisted in situ keratomileusis, and 6 eyes underwent photorefractive keratectomy. Read More

Int Ophthalmol 2019 Mar 1. Epub 2019 Mar 1.

Southwest Hospital, Southwest Eye Hospital, Army Medical University, Chongqing, People's Republic of China.

Purpose: To evaluate the efficiency of plasma exchange (PE) add-on on optic neuritis (ON) in neuromyelitis optica spectrum disorders (NMOSD).

Methods: Our ambispective, nonrandomized study was performed in Southwest Hospital, Southwest Eye Hospital, Army Medical University. We studied 31 consecutive NMOSD patients characterized by ON and hospitalized from September 2015 to May 2018. Read More

Int Ophthalmol 2019 Feb 23. Epub 2019 Feb 23.

Department of Ophthalmology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

Purpose: We investigated using ultrawide-field fundus images with a deep convolutional neural network (DCNN), which is a machine learning technology, to detect treatment-naïve proliferative diabetic retinopathy (PDR).

Methods: We conducted training with the DCNN using 378 photographic images (132 PDR and 246 non-PDR) and constructed a deep learning model. The area under the curve (AUC), sensitivity, and specificity were examined. Read More

Int Ophthalmol 2019 Feb 20. Epub 2019 Feb 20.

Clinica Oculistica, DiNOGMI, Università degli Studi di Genova, Viale Benedetto XV 5, 16132, Genoa, Italy.

Purpose: To create a diagnostic algorithm for the management of chorioretinal folds.

Methods: We reviewed the existing literature about chorioretinal folds focusing our attention on three specific conditions and created a diagnostic algorithm in order to otpimize the choice and the number of investigations.

Results: Chorioretinal folds are visible striations of the fundus usually arranged in parallel lines and disposed horizontally. Read More

Int Ophthalmol 2019 Feb 19. Epub 2019 Feb 19.

Università di Pisa-Dipartimento di patologia chirurgica medica, molecolare e dell'area critica, Via Savi n. 10, 56126, Pisa, PI, Italy.

Purpose: The aim of this study is to investigate potential correlations between age, gender, spherical equivalent and optical coherence tomography (OCT) retinal parameters among healthy children.

Methods: A macular spectral-domain OCT was performed in all patients using a Spectralis OCT device, and the macular thickness and volume of each of the early treatment diabetic retinopathy study (ETDRS) subfields were analysed.

Results: Ninety-four children were enrolled. Read More

Int Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Department of Preventive Medicine, Hospital Universitario Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.

Purpose: To describe indocyanine green angiography (ICGA) and visual acuity (VA) results in patients with neovascular age-related macular degeneration (nAMD) refractory to ranibizumab switched to aflibercept.

Methods: This study is a prospective interventional case series. Thirty-two eyes of 32 patients with nAMD showing a poor response after at least 24 months of ranibizumab were switched to aflibercept. Read More

Int Ophthalmol 2019 Feb 13. Epub 2019 Feb 13.

University of São Paulo (USP), São Paulo, Brazil.

Purpose: To evaluate the influence of preoperative mitomycin C (MMC) on the proliferative behavior of fibroblasts and fibrovascular tissue derived from the primary pterygium using the immunohistochemical method (Ki67 and CD34).

Design: Randomized clinical trial.

Subjects, Participants And/or Controls: Sixty-five patients with primary pterygium were randomly selected and divided into one of three groups. Read More

Int Ophthalmol 2019 Feb 6. Epub 2019 Feb 6.

Department of Optometry, School of Rehabilitation Science, Iran University of Medical Sciences, Tehran, Iran.

Purpose: To evaluate discrete wavelet transform coefficients and identify descriptors of pattern electroretinogram (PERG) waveforms in order to determine PERG characteristics for optimizing the diagnosis of early primary open-angle glaucoma (POAG).

Methods: Pattern electroretinogram was performed in 30 normal eyes and 30 eyes with primary open-angle glaucoma according to the ISCEV protocol. The check size was 0. Read More

Int Ophthalmol 2019 Feb 1. Epub 2019 Feb 1.

Department of Ophthalmology, Ege University School of Medicine, İzmir, Turkey.

Purpose: Retinal vasculitis and vein occlusions are common causes of serious visual loss in Behçet's disease. We aimed to evaluate the optical coherence tomography angiography (OCTA) findings of Behcet uveitis (BU) patients.

Methods: We evaluated 32 eyes of 16 patients with BU and 30 eyes of 15 healthy controls. Read More

Int Ophthalmol 2019 Feb 1. Epub 2019 Feb 1.

Department of Ophthalmology, University of Nigeria Teaching Hospital, PMB 01129, Ituku-Ozalla, Enugu, Nigeria.

Purpose: To investigate the current practice on glaucoma care with the aim of highlighting its poise to tackle this emerging sight-threatening disease in Nigeria.

Methods: This was a cross-sectional, descriptive, population-based survey involving 88 ophthalmologists. Information on their demographic characteristics, practice profile, challenges and prospects on glaucoma care was collected using a semi-structured, self-administered questionnaire in August 2016. Read More

Int Ophthalmol 2019 Feb 1. Epub 2019 Feb 1.

Department of Ophthalmology, Rambam Healthcare Campus, P.O.B 9602, 31096, Haifa, Israel.

Purpose: To describe a new technique for sealing small corneal perforations after penetrating trauma.

Methods: Corneal perforations in six eyes were sealed using a stromal cefuroxime hydration technique. This technique is identical to the current method used to seal leaking incisions upon completion of cataract surgery except for the use of cefuroxime instead of balanced salt solution. Read More

Int Ophthalmol 2019 Jan 24. Epub 2019 Jan 24.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 South Xianlie Road, Guangzhou, 510060, China.

Purpose: To investigate the predictors of long-term intraocular pressure (IOP) in chronic primary angle-closure glaucoma (CPACG) treated with primary trabeculectomy.

Methods: This study systematically reviewed cases of CPACG treated with primary trabeculectomy. The scleral flaps in all cases were sutured with two stitches in situ and two releasable sutures to ensure watertight under normal IOP conditions during surgery. Read More

Int Ophthalmol 2019 Jan 23. Epub 2019 Jan 23.

Department of Ophthalmology-Retina, Federal University of São Paulo, Alameda Santos, 333 - Apto 142, São Paulo, SP, CEP 01419-000, Brazil.

Purposes: To compare surgeons' opinions regarding idiopathic full-thickness macular hole (MH) surgery by using traditional microscopy and three-dimensional (3-D) visualization system. To analyze the required time for pars plana vitrectomy (PPV) and for internal limiting membrane (ILM) rhexis by using both visualization methods. To evaluate anatomical surgical results. Read More

Int Ophthalmol 2019 Jan 18. Epub 2019 Jan 18.

Queen Victoria Hospital, NHS Foundation Trust, East Grinstead, West Sussex, UK.

Background: To investigate response of dissolving collagen contact lenses as an alternative for bandage contact lenses, for the post-interventional care of epithelial defects after corneal cross-linking (CXL) treatment for keratoconus.

Patients And Methods: Follow-up visits were performed at day 1, 4 and 1 month after the intervention. We reviewed notes for re-epithelialization, comfort/pain and any untoward effects of Collagen SOFT SHIELD. Read More

Int Ophthalmol 2019 Jan 17. Epub 2019 Jan 17.

Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Purpose: The purpose of this article was to introduce a novel surgical technique for the management of peripheral Descemet's membrane perforation during deep anterior lamellar keratoplasty (DALK).

Methods: First, a thin stromal patch was prepared either from the anterior stromal lamella cut during DALK or from the anterior stroma of a Descemet's stripping automated endothelial keratoplasty button. The stromal patch was secured in a stromal pocket dissected deep in the trephination edge along the perforation site. Read More

Int Ophthalmol 2019 Jan 17. Epub 2019 Jan 17.

Nikookari Eye Hospital, Tabriz University of Medical Sciences, Tabriz, 5154645395, Iran.

Purpose: Comparison of the effect of mitomycin C (MMC) versus bevacizumab-methylcellulose mixture (BMM) on combined phacoemulsification and non-penetrating deep sclerectomy surgery on the intraocular pressure in patients with open-angle glaucoma was made.

Methods: The current study is a controlled, randomized, double-blind clinical trial. Thirty-eight patients were enrolled, with a total of 40 eyes, and underwent a combined phacoemulsification and non-penetrating deep sclerectomy surgery from 2016 to 2017. Read More

Int Ophthalmol 2019 Jan 14. Epub 2019 Jan 14.

Cornea and Refractive Surgery Department, Asociación Para Evitar la Ceguera (APEC), Universidad Nacional Autónoma de México, #46 Vicente García Torres, Delegación Coyoacán, 04030, México City, México.

Purpose: To translate and validate a Spanish-language adaptation of the 5-Item Dry Eye Questionnaire for the Mexican population.

Methods: Based on the MAPI Institute guidelines, the linguistic validation procedures consisted of four steps. Every step was reviewed by the committee. Read More

Int Ophthalmol 2019 Jan 12. Epub 2019 Jan 12.

Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.

Objective: The objective of this work was to find out the effects of nuclear factor erythroid 2-related factor/heme oxygenase-1 (Nrf2/HO-1) pathway on retinal ganglion cell (RGC) injury in glaucoma.

Methods: The chronic ocular hypertension (COH) rat models of glaucoma were constructed, and intraocular pressure (IOP) and RGC numbers were detected at different time points. Additionally, rats were divided into normal group (normal control rats), model group (COH model rats), and model + tBHQ group (COH model rats treated with Nrf activator, tBHQ). Read More

Int Ophthalmol 2019 Jan 9. Epub 2019 Jan 9.

2nd Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.

Purpose: To study the association of serum ionic calcium and glycated hemoglobin (HbA1c) with retinal photoreceptor ellipsoid zone (EZ) disruption in diabetic retinopathy (DR).

Methods: This is a tertiary care center-based observational cross-sectional study. Sixty-three consecutive cases, divided into 21 cases each with no diabetic retinopathy, non-proliferative diabetic retinopathy and proliferative diabetic retinopathy were included. Read More

Int Ophthalmol 2019 Jan 8. Epub 2019 Jan 8.

Department of Ophthalmology, Harran University Faculty of Medicine, 63300, Haliliye, Şanlıurfa, Turkey.

Purpose: The aim of the study was to measure amino acid levels with the metabolomics analysis in pterygium tissue and normal conjunctiva tissue.

Materials And Methods: In this prospective, randomized, clinical study, a comparison of the amino acid profile of pterygium tissue and normal conjunctiva tissue taken during autograft pterygium surgery was made. After homogenization of the tissues, amino acid levels were measured with chromatography-mass spectrometry (LC-MS/MS) in the biochemistry laboratory. Read More

Int Ophthalmol 2019 Jan 4. Epub 2019 Jan 4.

Eye Clinic Sulzbach, Knappschaft Hospital Saar, An der Klinik 10, 66280, Sulzbach, Saarland, Germany.

Purpose: The aim of this study was to investigate the clinical outcome after standardized DMEK using a glass injector.

Methods: A total of 254 patients undergoing DMEK surgery using a disposable DMEK borosilicate glass cartridge system were included in this retrospective study. The mean follow-up time was 13. Read More

Int Ophthalmol 2019 Jan 3. Epub 2019 Jan 3.

Department of Ophthalmology, Jingzhou First People's Hospital, Jingzhou, Hubei, China.

Objective: To understand the involvement of the mGluR5-mediated JNK signaling pathway in rats with diabetic retinopathy (DR).

Methods: This study established rat models of diabetes mellitus (DM), which were divided into Normal, DM, DM + CHPG (mGluR5 agonist CHPG), and DM + MTEP (mGluR5 antagonist MTEP) groups. The blood glucose and weight of rats were recorded. Read More

Int Ophthalmol 2019 Jan 3. Epub 2019 Jan 3.

State Key Laboratory of Precision Measurement Technology and Instruments, Tianjin University, Tianjin, 300072, China.

Purpose: The mechanisms of naso-ocular interaction in allergic rhinoconjunctivitis are not well understood. Neurogenic inflammation affects both eyes and nose via the same neurogenic factors. The purpose of this study was to investigate the effects of neurogenic inflammation on conjunctival inflammation following nasal allergen provocation. Read More

Int Ophthalmol 2019 Jan 3. Epub 2019 Jan 3.

Department of Ophthalmology, Akdeniz University Medical Faculty, Antalya, Turkey.

Purpose: To evaluate the retinal and choroidal vascular changes through optical coherence tomography angiography (OCTA) in patients with macular telangiectasia type 2 (MacTel 2).

Methods: Our study included 20 patients (40 eyes) with MacTel 2, and age-matched and sex-matched 18 subjects (36 eyes) in the control group. Fundus color photographs, fundus autofluorescence, fundus fluorescein angiography, spectral-domain optical coherence tomography and OCTA were performed. Read More

Int Ophthalmol 2019 Jan 3. Epub 2019 Jan 3.

Centre for Sight, Road No 2 Banjara Hills, Hyderabad, 500034, India.

Purpose: The objective of this study was to investigate the efficacy and safety of phaco-endocycloplasty in an exclusive cohort of primary angle closure disease/glaucoma.

Methods: The study was interventional and non-comparative, carried out at a tertiary level eye care Institute. All adult patients (> 18 years) with angle closure disease, who had controlled or uncontrolled intra-ocular pressure (IOP) and had visually significant cataract, requiring surgery, and had undergone phaco-endocycloplasty, performed for 180°-210° simultaneously with cataract surgery, were included. Read More

Int Ophthalmol 2019 Jan 2. Epub 2019 Jan 2.

Ophthalmology Clinics, Bakırkoy Dr. Sadi Konuk Training and Research Hospital, Bakirkoy, Istanbul, Turkey.

Purpose: To investigate the extent of vascularization of the peripheral retina and vascular development patterns in patients with type 1 retinopathy of prematurity (ROP) treated with intravitreal injection of bevacizumab (IVB) and compare fluorescein angiography (FA) findings of them to those seen in patients with type 2 ROP who have recovered spontaneously.

Methods: Between May 2014 and September 2016, patients with type 1 ROP who had a single 0.025 ml (0. Read More

Int Ophthalmol 2019 Feb;39(2):491-495

S. Anna Clinical Institute, Via del Franzone, 31, 25127, Brescia, Italy.

Purpose: To demonstrate the safety and efficacy of partial thickness sclerectomies to treat exudative retinal detachment secondary to choroidal hemangioma, non-suitable with photodynamic therapy in a 5-year-old child with Sturge-Weber syndrome.

Methods: A 5 year-old child presented exudative retinal detachment secondary to choroidal subfoveal diffuse hemangioma. The child was non-compliant to undergo a photodynamic therapy. Read More

Int Ophthalmol 2018 Dec 7. Epub 2018 Dec 7.

Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

Purpose: To evaluate the effect of topical sodium hyaluronate (SH) 0.18% treatment on corneal epithelial healing after epithelial debridement in pars plana vitrectomy in diabetic patients.

Method: This is prospective and randomized clinical trial. Read More

Int Ophthalmol 2018 Dec 8. Epub 2018 Dec 8.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th Street, Miami, FL, 33136, USA.

Purpose: To evaluate corneal edema in different-aged pediatric patients with Peters anomaly and to correlate in vivo with ex vivo histopathologic findings.

Methods: A retrospective cross-sectional study was performed. The medical records of patients diagnosed with Peters anomaly who underwent examination under anesthesia (EUA) between 2011 and 2015 were reviewed. Read More

Int Ophthalmol 2018 Dec 8. Epub 2018 Dec 8.

Ophthalmic Pathology Laboratory (DKM), L V Prasad Eye Institute, Hyderabad, India.

Purpose: To study the concordance between intra-operative rapid frozen section and permanent section diagnoses of surgical margins following wide surgical excisional biopsy of malignant eyelid tumors.

Methods: This is a retrospective study of 120 cases and 429 frozen section slides.

Results: Of 120 cases, 75 (63%) had sebaceous gland carcinoma, 34 (28%) had basal cell carcinoma, and 11 (9%) had squamous cell carcinoma. Read More

Int Ophthalmol 2018 Dec 3. Epub 2018 Dec 3.

Department of Ophthalmology, Yildirim Beyazit University Faculty of Medicine, Ankara Ataturk Training and Research Hospital, Ankara, Turkey.

Purpose: To investigate the elasticity of ocular structures in patients with rheumatoid arthritis (RA) without ocular involvement.

Methods: The study included 56 RA patients (study group) and 24 healthy volunteers as the control group. The rheumatoid arthritis patients were divided into two subgroups as those in active phase (Group 1, n = 25) or in remission phase (Group 2, n = 31) according to the disease activity index (DAS 28) score. Read More

Int Ophthalmol 2018 Nov 28. Epub 2018 Nov 28.

Department of Ophthalmology, V.M.M.C & Safdarjung Hospital, Room No. 430 of Eye OPD, 4th Floor of OPD Building, Ansari Nagar, Ring Road, New Delhi, 110029, India.

Purpose: To evaluate and compare the change in postoperative central macular thickness in patients receiving benzalkonium chloride (BKC)-preserved and BKC-free medications after uneventful phacoemulsification.

Setting: V.M. Read More

Int Ophthalmol 2018 Nov 26. Epub 2018 Nov 26.

Universidade Federal do Rio Grande do Sul (UFRGS), Cabral 732/1204, Porto Alegre, RS, 90420-121, Brazil.

Purpose: To compare choroidal thickness (CT) measurements in preeclamptic and healthy women in the third trimester of pregnancy using optical coherence tomography.

Methods: This cross-sectional study included 148 eyes of 74 women, divided into two groups: 27 healthy pregnant women in the third trimester (control group) and 47 age-matched pregnant women in the third trimester with preeclampsia (PE group). Of the 47 subjects in preeclampsia group, 26 were classified as having mild PE and 21 as having severe PE. Read More

Int Ophthalmol 2018 Nov 26. Epub 2018 Nov 26.

Department of Medical Biology and Genetics, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.

Purpose: Duane retraction syndrome (DS) is a rare congenital strabismus with genetic heterogeneity. The genetic causes of DS are not always of monogenic origin; various chromosomal copy number variations (CNVs) have also been reported. The objective of our study was to characterize the CNVs, including gains and losses detected by high-resolution chromosomal microarray in patients with DS. Read More