2,098 results match your criteria International Journal of Surgical Pathology [Journal]


Anthracofibrotic Lymph Node of Neck Mimicking Metastatic Malignant Melanoma in a Patient With Gastric Cancer.

Int J Surg Pathol 2019 Apr 24:1066896919845060. Epub 2019 Apr 24.

1 Chonnam National University, Gwangju, South Korea.

Extrathoracic anthracofibrosis in head and neck region is of extremely rare occurrence and can be confused with malignancy. In this article, we report an unusual case of an anthracofibrotic lymph node of neck that was mistaken for metastatic malignant melanoma in a gastric cancer patient. Because the incidence of an anthracofibrotic lymph node of the neck is very low, it is important to distinguish it from other diseases, including malignancy or metastasis, especially in patients with a cancer history. Read More

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http://dx.doi.org/10.1177/1066896919845060DOI Listing

Bone Marrow Biopsy Disclosing a Rare Osteolytic Disorder: Gorham-Stout Syndrome.

Int J Surg Pathol 2019 Apr 24:1066896919844319. Epub 2019 Apr 24.

3 University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1177/1066896919844319DOI Listing

Cecal Mucosal Myxoma: The First Report of a New Type of Mesenchymal Colon Polyp.

Int J Surg Pathol 2019 Apr 22:1066896919843625. Epub 2019 Apr 22.

1 University of Rochester, Rochester, NY, USA.

Myxomas are benign mesenchymal neoplasms of unknown etiology that most commonly occur in the cardiac atrium; however, other reported sites include the skin, joints, skeletal muscles, maxillofacial bones, and sinonasal tract. Myxomas involving the gastrointestinal (GI) tract are rare and are limited to a few published case reports. We are presenting, to our knowledge, the first case report of a mucosal myxoma in the colon presenting as a colonic polyp. Read More

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http://dx.doi.org/10.1177/1066896919843625DOI Listing

Leiomyomatous Hamartomas of the Oral Cavity: Clinicopathological and Immunohistochemical Features of 4 Cases and Literature Review.

Int J Surg Pathol 2019 Apr 16:1066896919843337. Epub 2019 Apr 16.

5 Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.

Objective: To present 4 new cases of oral leiomyomatous hamartomas (OLH), describing its clinical, microscopical, and immunohistochemical features, and a literature review.

Methods: The OLH cases were retrieved from the files of 2 Brazilian and 1 Peruvian oral pathology services. Clinical data were obtained from the pathology reports. Read More

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http://dx.doi.org/10.1177/1066896919843337DOI Listing

Clinicopathologic Characterization of Bilateral Testicular Germ Cell Tumors With Immunohistochemical Evaluation of Mismatch Repair and BRAF (V600E) Genes Mutations.

Int J Surg Pathol 2019 Apr 15:1066896919842939. Epub 2019 Apr 15.

1 Indiana University, Indianapolis, IN, USA.

The incidence of bilateral testicular germ cell tumor (TGCT) is 1% to 5%. Despite the high rate of treatment success, resistance to chemotherapy has a detrimental effect. Some studies found MMR and BRAF gene mutations to be associated with chemotherapy resistance, which has not been found by others. Read More

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http://dx.doi.org/10.1177/1066896919842939DOI Listing
April 2019
1 Read

Renal Cell Carcinoma With Hemangioma-Like Features: Diagnostic Implications and Review of the Literature.

Int J Surg Pathol 2019 Apr 8:1066896919840435. Epub 2019 Apr 8.

2 Yonsei University, Seoul, Republic of Korea.

Renal cell carcinoma (RCC) with clear cell morphology may show a prominent delicate vascularity. In this article, we report the morphologic and immunohistochemical features of a clear cell papillary RCC mimicking hemangioblastoma and a clear cell RCC mimicking hemangioma. Case 1 showed tubular and papillary growth of clear cells with distinctive areas of capillary proliferation and admixed stromal-like cells resembling a hemangioblastoma. Read More

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http://dx.doi.org/10.1177/1066896919840435DOI Listing
April 2019
1 Read

Sclerosing Tumors of the Gastrointestinal Tract: A Systematic Approach.

Int J Surg Pathol 2019 Apr 8:1066896919840431. Epub 2019 Apr 8.

1 Toronto General Hospital, Toronto, Ontario, Canada.

Some lesions in the gastrointestinal tract have a propensity for sclerosis such that it may mask the actual true nature of the lesion. The purpose of this review is to highlight those lesions of the gastrointestinal tract that can be attended by sclerosis. The sclerosis can mask the cellularity of the lesion; hence, knowledge of the key lesions that are known to have sclerosis will be aid the diagnostic pathologist. Read More

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http://dx.doi.org/10.1177/1066896919840431DOI Listing
April 2019
1 Read

Mixed Adenocarcinomatous and Neuroendocrine Tumor of the Urinary Bladder With Concomitant Carcinoma In Situ: A Case Report With a Comprehensive Immunohistochemical Analysis and Review of the Literature.

Int J Surg Pathol 2019 Apr 8:1066896919839781. Epub 2019 Apr 8.

1 Robert-Bosch-Hospital, Stuttgart, Germany.

Mixed adenoneuroendocrine carcinomas are rare and usually occur in the gastrointestinal tract. Although there have been several investigations regarding their developmental mechanism, the molecular origin of these tumors remains unclear. In this article, we present an exceedingly rare case of a mixed tumor of the urinary bladder with an adenocarcinomatous and a neuroendocrine component and a concomitant urothelial carcinoma in situ (CIS). Read More

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http://dx.doi.org/10.1177/1066896919839781DOI Listing
April 2019
1 Read

Adenocarcinoma With Osseous Metaplasia: Is It Bad to the Bone?

Int J Surg Pathol 2019 Apr 8:1066896919842204. Epub 2019 Apr 8.

1 University of Genova, Genova, Italy.

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http://dx.doi.org/10.1177/1066896919842204DOI Listing

Undifferentiated Sarcoma as Intermediate Step in Rhabdomyosarcomatous Transformation of a Metastatic Malignant Melanoma Resistant to Anti-BRAF Therapy: A Phenomenon Associated With Significant Diagnostic and Therapeutic Pitfalls.

Authors:
Tien Anh N Tran

Int J Surg Pathol 2019 Apr 3:1066896919839143. Epub 2019 Apr 3.

1 Florida Orlando Hospital, Orlando, FL, USA.

Undifferentiated sarcoma has been hypothesized as an intermediate step in the progression of malignant melanoma to rhabdomyosarcoma. The current report describes a new case of rhabdomyosarcomatous transformation in a malignant melanoma and documents the temporal progression of the malignant melanoma to rhabdomyosarcoma in different metastatic sites via undifferentiated sarcoma. A 65-year-old female with a past medical history of malignant melanoma presented with a new lung mass. Read More

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http://dx.doi.org/10.1177/1066896919839143DOI Listing
April 2019
8 Reads

Gastric Heterotopia: Ileal Thickening in a Patient With Jejunal Atresia Type IIIb.

Int J Surg Pathol 2019 Apr 3:1066896919840434. Epub 2019 Apr 3.

1 The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1177/1066896919840434DOI Listing
April 2019
2 Reads

Epithelioid Hemangioendothelioma Arising Within Mediastinal Myelolipoma: A WWTR1-Driven Composite Neoplasm.

Int J Surg Pathol 2019 Apr 3:1066896919837611. Epub 2019 Apr 3.

1 Department of Pathology, Miller School of Medicine, University of Miami, Miami, FL, USA.

In this article, we describe a case of conventional epithelioid hemangioendothelioma (EHE) arising within an extra-adrenal myelolipoma. This composite neoplasm arose in the mediastinum of a 51-year-old female. The tumor was composed of a large myelolipoma that contained nodules of EHE consisting of CD31-positive epithelioid endothelial cells that grew in solid cords and were enmeshed in a basophilic hyalinized stroma. Read More

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http://dx.doi.org/10.1177/1066896919837611DOI Listing
April 2019
3 Reads
0.961 Impact Factor

Role of Immunohistochemistry in the Subtyping of Periampullary Adenocarcinoma.

Int J Surg Pathol 2019 Apr 3:1066896919837606. Epub 2019 Apr 3.

1 Sir Ganga Ram Hospital, New Delhi, India.

Context: Subtyping of periampullary adenocarcinoma into intestinal and pancreatobiliary subtypes has emerged as an important prognostic factor with potential therapeutic implications. This distinction on morphology alone is often difficult with significant interobserver variability.

Objective: To analyze the usefulness of a panel of immunohistochemistry (IHC) markers as an aid to morphologic subtyping of periampullary adenocarcinoma. Read More

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http://dx.doi.org/10.1177/1066896919837606DOI Listing
April 2019
1 Read
0.961 Impact Factor

Florid Vascular Proliferation of the Small Bowel and Colon, a Potential Masquerader of Malignancy: Report of Three Cases.

Int J Surg Pathol 2019 Apr 3:1066896919837665. Epub 2019 Apr 3.

1 University of Rochester Medical Center, Rochester, NY, USA.

Vascular abnormalities and lesions of the small bowel and colon are rare. A florid vascular proliferation (FVP) associated with colon obstruction and intussusception has been described and can mimic malignant vascular tumors such as angiosarcoma. In this article, we report a case of colonic FVP associated with colon obstruction, a case of small bowel FVP associated with a Meckel's diverticulum, and a case of small bowel FVP with intussusception. Read More

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http://dx.doi.org/10.1177/1066896919837665DOI Listing
April 2019
4 Reads

Clear Cell Variant of Papillary Thyroid Carcinoma With Associated Anaplastic Thyroid Carcinoma: Description of an Extraordinary Case.

Int J Surg Pathol 2019 Apr 1:1066896919837678. Epub 2019 Apr 1.

1 Department of Oncology-Pathology, Karolinska Institutet, Solna, Sweden.

Clear cell change is a rare observation in thyroid cancer, resulting from aberrant cytoplasmic accumulation of lipids, glycogen, or thyroglobulin in the tumor cells. The phenomenon is most common for follicular thyroid neoplasia, with no definite coupling to patient outcome. The clear cell variant of papillary thyroid carcinoma (ccPTC) is even more infrequent-making conclusions regarding prognosis difficult. Read More

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http://dx.doi.org/10.1177/1066896919837678DOI Listing
April 2019
2 Reads

Clear Cell Lesions of the Mullerian System: Not Always That "Clear"!

Int J Surg Pathol 2019 Mar 27:1066896919835929. Epub 2019 Mar 27.

1 Brown University, Providence, RI, USA.

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http://dx.doi.org/10.1177/1066896919835929DOI Listing

Ovarian Carcinosarcoma and Concurrent Serous Tubal Intraepithelial Carcinoma With Next-Generation Sequencing Suggesting an Origin From the Fallopian Tube.

Int J Surg Pathol 2019 Mar 27:1066896919838347. Epub 2019 Mar 27.

1 Department of Pathology, McGaw Medical Center of Northwestern University, Chicago, IL, USA.

Background: Ovarian carcinosarcomas are rare aggressive biphasic tumors. Evidence suggests that these tumors are monoclonal and that the sarcoma component is derived from a stem cell undergoing divergent differentiation. Currently, there remains a paucity of data regarding its origin, with few reports suggesting an association with serous tubal intraepithelial carcinoma (STIC) by immunohistochemistry and genetics. Read More

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http://dx.doi.org/10.1177/1066896919838347DOI Listing

Intratubular Teratoma: A Rare Form of Testicular Germ Cell Neoplasia.

Int J Surg Pathol 2019 Mar 24:1066896919836491. Epub 2019 Mar 24.

1 Northwell Health Lenox Hill Hospital, New York, NY, USA.

Germ cell neoplasia in situ is the initial manifestation for invasive germ cell tumor. Further progression will result in intratubular germ cell tumor with the majority being intratubular seminoma or intratubular embryonal carcinoma. Intratubular teratoma in the testis is exceptionally rare with no well-documented cases to our knowledge. Read More

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http://dx.doi.org/10.1177/1066896919836491DOI Listing
March 2019
1 Read
0.961 Impact Factor

Extra-Adrenal Adult Neuroblastoma With Aberrant Germ Cell Marker Expression: Maturation After Chemotherapy as an Important Clue to a Challenging Diagnosis.

Int J Surg Pathol 2019 Mar 24:1066896919835945. Epub 2019 Mar 24.

1 Hospital Clinico Universitario, Valencia, Spain.

Adult neuroblastoma is an extremely infrequent neoplasm, usually occurring in the adrenal medulla or in the paraspinal sympathetic ganglia, as its childhood counterpart. We report a very unusual case of a Schwannian stroma-poor adult neuroblastoma of inguinal location, showing aberrant expression of germ cell markers: SALL4 and OCT4. This aberrant marker expression, the unusual positivity for NKX2. Read More

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http://dx.doi.org/10.1177/1066896919835945DOI Listing

Primary Pulmonary Acinic Cell Carcinoma: A Clinicopathological Study of 6 Cases and Literature Review.

Int J Surg Pathol 2019 Mar 21:1066896919836499. Epub 2019 Mar 21.

1 The Affiliated Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu Province, China.

Primary pulmonary acinic cell carcinoma (ACC) is rare. The clinicopathological features are not identical to that of classic ACC that leads to misdiagnosis. In this article, we summarized the clinicopathological features of 25 such cases, including 6 cases in this series and additional 19 cases in the literature. Read More

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http://dx.doi.org/10.1177/1066896919836499DOI Listing

Xanthomatous Interstitial Pneumopathy: Chemotherapy- or Contrast Substance Related Change?

Int J Surg Pathol 2019 Mar 22:1066896919837741. Epub 2019 Mar 22.

1 APHP GHU, Bobigny, France.

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http://dx.doi.org/10.1177/1066896919837741DOI Listing

A Case of Pseudomelanosis Duodeni: Striking Endoscopic Features With Subtle but Characteristic Pathologic Findings.

Int J Surg Pathol 2019 Mar 17:1066896919835939. Epub 2019 Mar 17.

2 Louisiana State University, New Orleans, LA, USA.

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http://dx.doi.org/10.1177/1066896919835939DOI Listing

The Sick Breast Lobe Has a Testicular Counterpart.

Int J Surg Pathol 2019 Mar 17:1066896919835928. Epub 2019 Mar 17.

1 University Hospital Saint-Luc, Brussels, Belgium.

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http://dx.doi.org/10.1177/1066896919835928DOI Listing

Abdominal Ectopic Thyroid Tissue: The Man From Istanbul.

Int J Surg Pathol 2019 Mar 14:1066896919833784. Epub 2019 Mar 14.

1 University of Genoa, Genoa, Italy.

Thyroid ectopia is a rare finding below the diaphragm. It is characterized by normal thyroid parenchyma in unusual locations with preserved thyroid marker immunoreactivity. In this article, we present the first known case of thyroid tissue in the periappendiceal fat and discuss possible ethiopathogenic theories. Read More

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http://dx.doi.org/10.1177/1066896919833784DOI Listing

Molecular Pathologic Subtyping of Urothelial Bladder Carcinoma in Young Patients.

Int J Surg Pathol 2019 Mar 11:1066896919830509. Epub 2019 Mar 11.

1 Clinical Research and Practical Center for Specialized Oncological Care, Saint Petersburg, Russia.

Urothelial cancer is a heterogeneous disease with different molecular pathways that produce distinct molecular subtypes with specific characteristics and patient survival outcomes that require different therapeutic methods. Urothelial tumors in young patients appear to have distinct genetic features compared with their counterparts in older patients. Using a Lund subtype-specific immunohistochemistry panel, we performed molecular subtype profiling of an urothelial carcinoma case series (n = 49) in patients younger than 45 years of age. Read More

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http://dx.doi.org/10.1177/1066896919830509DOI Listing

Yellow Is the New Black.

Int J Surg Pathol 2019 Mar 7:1066896919833168. Epub 2019 Mar 7.

1 University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1177/1066896919833168DOI Listing

Clear Cell Variant of Solid Pseudopapillary Neoplasm of the Pancreas: A Report of a Rare Variant and Review of the Literature.

Int J Surg Pathol 2019 Mar 7:1066896919833790. Epub 2019 Mar 7.

1 University of Southern California, Los Angeles, CA, USA.

The clear cell variant of solid pseudopapillary neoplasm (ccSPN) of the pancreas was first described in 2006. In this article, we report a case of this rare variant and review the few published reports. Both the current and previous reports show that ccSPN has several morphologic differences from conventional SPN, including clear vacuoles, fewer pseudopapillary formations, more solid/diffuse architecture, less hemorrhage, and fewer cholesterol clefts. Read More

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http://dx.doi.org/10.1177/1066896919833790DOI Listing

Palisaded Encapsulated (Solitary Circumscribed) Neuroma: A Review of 30 Cases.

Int J Surg Pathol 2019 Mar 5:1066896919833172. Epub 2019 Mar 5.

1 Istanbul Education and Research Hospital, Istanbul, Turkey.

Background: Solitary circumscribed neuroma (SCN), also known as palisaded encapsulated neuroma (PEN), is a benign neural tumor. It may be mistaken as either schwannoma or neurofibroma in pathology practice. In this study, we aimed to define clinicopathologic and immunohistochemical features and discuss its differential diagnosis. Read More

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http://dx.doi.org/10.1177/1066896919833172DOI Listing
March 2019
10 Reads

A Case of Clear Cell Papillary Renal Cell Carcinoma With Prominent Glycogen-Containing Intranuclear Inclusions.

Int J Surg Pathol 2019 Feb 27:1066896919832098. Epub 2019 Feb 27.

1 University of Maryland Medical Center, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/1066896919832098DOI Listing
February 2019
1 Read

Autoamputation of Dermatofibrosarcoma Protuberans: A Novel and Rare Presentation of a Familiar Entity.

Int J Surg Pathol 2019 Feb 27:1066896919832658. Epub 2019 Feb 27.

1 Henry Ford Health System, Detroit, MI, USA.

Dermatofibrosarcoma protuberans (DFSP) is categorized as a fibrohistiocytic tumor of intermediate malignant potential. It has significant risk for local recurrence and, less commonly, local or distant metastasis. Initially, these tumors typically arise as a firm plaque on the skin that slowly progresses to a nodular and protuberant dermal lesion. Read More

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http://dx.doi.org/10.1177/1066896919832658DOI Listing
February 2019

Chronic Myeloid Leukemia With Myelofibrosis-Like Features. Clues of Accelerated Phase?

Int J Surg Pathol 2019 Feb 27:1066896919833170. Epub 2019 Feb 27.

1 Hematology and Clinical Immunology Unit, University of Padua, Padova, Italy.

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http://dx.doi.org/10.1177/1066896919833170DOI Listing
February 2019

Lymphocytic Gastritis Overshadowed by Gastric Mucosa-Associated Lymphoid Tissue Lymphoma.

Int J Surg Pathol 2019 Feb 17:1066896919830498. Epub 2019 Feb 17.

2 Dubai Hospital, Dubai, United Arab Emirates.

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http://dx.doi.org/10.1177/1066896919830498DOI Listing
February 2019
1 Read

IgG4-Related Appendiceal Disease: A First Case Report Fulfilling All Pathological Diagnostic Criteria and With Concomitant S100-Positive Dendritic/Schwann Cell Hyperplasia.

Int J Surg Pathol 2019 Feb 17:1066896919830213. Epub 2019 Feb 17.

1 Georgetown University Hospital, Washington, DC, USA.

IgG4-related disease is a recent entity that has been described in a wide variety of organ systems. A 46-year-old female presented with acute appendicitis accompanied by a mass-forming lesion, raising a concern for neoplasm, and therefore, hemicolectomy was performed. The lesion revealed a dense lymphoplasmacytic infiltrate accompanied by storiform fibrosis and obliterative phlebitis. Read More

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http://dx.doi.org/10.1177/1066896919830213DOI Listing
February 2019
4 Reads

Multifocal Synchronous Upper Urinary Tract Carcinosarcoma (Sarcomatoid Carcinoma) With Rhabdomyoblastic Differentiation.

Int J Surg Pathol 2019 Feb 15:1066896919828111. Epub 2019 Feb 15.

1 Department of Urology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.

Carcinosarcoma of the upper urinary tract is very rare. In this article, we report a case of upper urinary tract carcinosarcoma with rhabdomyoblastic differentiation showing distinct transition between the epithelial and mesenchymal components confirmed by morphology and immunohistochemistry. An 81-year-old female underwent radical nephroureterectomy under the diagnosis of left ureteral urothelial carcinoma (UC). Read More

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http://dx.doi.org/10.1177/1066896919828111DOI Listing
February 2019
1 Read

Sarcomatoid Carcinoma With Quasi-Complete Loss of Cytokeratin Expression or Keratin-Positive Atypical Fibroxanthoma.

Int J Surg Pathol 2019 Feb 14:1066896919830208. Epub 2019 Feb 14.

1 University of Montreal, Montreal, Quebec, Canada.

We report the case of a 94-year-old man with a rapidly growing nodule on the preauricular area, which on histology showed a poorly differentiated spindle cell tumor with negative p63 and p40 antibody immunostains, negative high- and low-molecular-weight cytokeratins albeit for a focal expression of cytokeratin AE1/AE3. Spindle cell melanoma, angiosarcoma, and leiomyosarcoma were excluded. We explore the diagnostic approach to this challenging conundrum. Read More

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http://dx.doi.org/10.1177/1066896919830208DOI Listing
February 2019
7 Reads

Solid Cell Nests of the Thyroid Gland With Cartilaginous Differentiation: An Exceptionally Rare Morphological Phenomenon.

Int J Surg Pathol 2019 Feb 6:1066896919829221. Epub 2019 Feb 6.

1 Department of Pathology, Ghent University and Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1177/1066896919829221DOI Listing
February 2019

Verruciform Xanthoma of the Oral Mucosa: A Series of Eight Typical and Three Anomalous Cases.

Int J Surg Pathol 2019 Feb 6:1066896919827374. Epub 2019 Feb 6.

1 Queen Victoria Hospital NHSF Trust, East Grinstead, West Sussex, UK.

In this series, there are 8 typical verruciform xanthomas of the oral mucosa and 3 anomalies, 1 polypoid, 1 florid, and 1 carcinomatous. All were characterized by infiltrates of CD68-positive xanthomatous histiocytes in the lamina propria. The 11 patients comprised 6 men and 5 women (mean age = 54. Read More

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http://dx.doi.org/10.1177/1066896919827374DOI Listing
February 2019
1 Read

Bone Sarcoma With EWSR1-NFATC2 Fusion: Sarcoma With Varied Morphology and Amplification of Fusion Gene Distinct From Ewing Sarcoma.

Int J Surg Pathol 2019 Feb 3:1066896919827093. Epub 2019 Feb 3.

1 Queen Elizabeth Hospital, Hong Kong, SAR China.

Ewing sarcomas are typified by EWSR1 fusion to ETS gene family members. Tumors with fusion partners other than ETS family members and atypical histologic features pose significant diagnostic challenges and controversies as to their classification. In this article, we report a tumor with EWSR1-NFATC2 fusion in the left femur of a 43-year-old man and with unusual morphologic features that resemble undifferentiated high-grade sarcoma. Read More

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http://dx.doi.org/10.1177/1066896919827093DOI Listing
February 2019

Pilar Cysts' Epithelial Separation.

Int J Surg Pathol 2019 Jan 31:1066896919828100. Epub 2019 Jan 31.

2 Yale University, New Haven, CT, USA.

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http://dx.doi.org/10.1177/1066896919828100DOI Listing
January 2019
2 Reads

Villous Adenoma Arising in the Native Bladder Mucosa and the Upper Urinary Tract With Coexisting Neuroendocrine Carcinoma Following Augmentation Cystoplasty.

Int J Surg Pathol 2019 Jan 31:1066896919826708. Epub 2019 Jan 31.

1 University of Pennsylvania, Philadelphia, PA, USA.

Villous adenomas arising in the bladder following augmentation cystoplasty procedures are exceedingly rare. Even rarer is their occurrence in the native bladder mucosa and the upper urinary tract. In this article, we present a unique case of multifocal recurrent villous adenoma involving native bladder mucosa of an augmented bladder, bilateral ureters, and renal pelvis, with coexistent foci of adenocarcinoma and neuroendocrine carcinoma, in a patient with history of augmentation colocystoplasty. Read More

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http://dx.doi.org/10.1177/1066896919826708DOI Listing
January 2019
1 Read

Colon Metastasis From Microscopic Serous Carcinoma of the Fallopian Tube Fimbria Mimicking a Primary Colon Cancer.

Int J Surg Pathol 2019 Jan 20:1066896918824028. Epub 2019 Jan 20.

1 NTT Medical Center Tokyo, Tokyo, Japan.

Metastatic diseases rarely develop in the colorectum, and diagnosing colorectal metastasis by biopsy without history of a malignant tumor or clinical information of a primary tumor is challenging. A 65-year-old woman with a 6-month history of constipation and diarrhea was admitted to our hospital and diagnosed with rectosigmoid colonic micropapillary carcinoma. Low anterior resection was performed after neoadjuvant chemotherapy. Read More

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http://journals.sagepub.com/doi/10.1177/1066896918824028
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http://dx.doi.org/10.1177/1066896918824028DOI Listing
January 2019
18 Reads

Myxoid Myofibroblastoma of the Breast With Atypical Cells.

Int J Surg Pathol 2019 Jan 20:1066896918824406. Epub 2019 Jan 20.

1 University of Florida, Gainesville, FL, USA.

The differential diagnosis of myxoid lesions in the breast is broad and includes both benign and malignant entities. Assessment is particularly challenging on core biopsy specimens. Myofibroblastoma, initially thought to be more common in the adult male breast, is being recognized with increasing frequency in the female breast. Read More

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http://dx.doi.org/10.1177/1066896918824406DOI Listing
January 2019
1 Read

Lymphocytic Esophagitis: Inflammatory Pattern of Candida Esophagitis in a Patient With Ulcerative Colitis.

Int J Surg Pathol 2019 Jan 16:1066896918824023. Epub 2019 Jan 16.

1 Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1177/1066896918824023DOI Listing
January 2019
2 Reads
0.961 Impact Factor

Continuous Spatial Sequences of Lichen Sclerosus, Penile Intraepithelial Neoplasia, and Invasive Carcinomas: A Study of 109 Cases.

Int J Surg Pathol 2019 Jan 7:1066896918820960. Epub 2019 Jan 7.

1 Instituto de Patología e Investigación, Asunción, Paraguay.

Lichen sclerosus (LSc) with penile cancer is found in about two thirds of specimens. It has been hypothesized that LSc represents a precancerous condition. To qualify as such, in addition to cytological atypia and similarity with the invasive tumor, a spatial correlation between LSc and neoplastic lesions needs to be demonstrated. Read More

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http://journals.sagepub.com/doi/10.1177/1066896918820960
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http://dx.doi.org/10.1177/1066896918820960DOI Listing
January 2019
10 Reads

Mucoepidermoid Carcinoma of the Gallbladder: A Case-Based Study of an Extremely Rare Tumor Highlighting the Role of Immunohistochemical Profiling.

Int J Surg Pathol 2018 Dec 26:1066896918821436. Epub 2018 Dec 26.

1 Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi, India.

Mucoepidermoid carcinoma (MEC) is rarely reported in the hepatobiliary system. In this article, we detail the first case of MEC arising from the gallbladder, presenting in a 50-year-old male. Imaging and gross examination showed a large mass in the gallbladder fossa infiltrating the liver. Read More

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http://dx.doi.org/10.1177/1066896918821436DOI Listing
December 2018
3 Reads

Mammary Epithelial-Myoepithelial Carcinoma: Report of a Case With HRAS and PIK3CA Mutations by Next-Generation Sequencing.

Int J Surg Pathol 2018 Dec 25:1066896918821182. Epub 2018 Dec 25.

1 Weill Cornell Medicine, New York, NY, USA.

We present the case of a 73-year-old woman with an epithelial-myoepithelial carcinoma of the left breast (ie, malignant adenomyoepithelioma). In both the initial needle core biopsy and in the subsequently performed lumpectomy, the tumor consisted of nests of neoplastic epithelium and myoepithelium with cytologic atypia, increased mitoses, and infiltrative growth into the surrounding tissue. Mutational analysis showed oncogenic driver mutations in HRAS and PIK3CA. Read More

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http://dx.doi.org/10.1177/1066896918821182DOI Listing
December 2018
13 Reads

Proliferative Funiculitis-Like Dedifferentiated Liposarcoma With Mesothelial Glandular Structures: A Diagnostic Pitfall.

Int J Surg Pathol 2019 May 24;27(3):271-273. Epub 2018 Dec 24.

1 Clinical Research and Practical Center for Specialized Oncological Care, Saint Petersburg, Russia.

Dedifferentiated liposarcoma shows a wide morphological spectrum. We present a case of dedifferentiated liposarcoma of the spermatic cord in a 66-year-old male that was initially misinterpreted as pseudosarcomatous proliferative funiculitis with mesothelial proliferation. Read More

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http://journals.sagepub.com/doi/10.1177/1066896918820443
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http://dx.doi.org/10.1177/1066896918820443DOI Listing
May 2019
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Chondromyxoid Fibroma of the Pelvis: Institutional Case Series With a Focus on Distinctive Features.

Int J Surg Pathol 2018 Dec 23:1066896918820446. Epub 2018 Dec 23.

1 Johns Hopkins University, Baltimore, MD, USA.

Chondromyxoid fibroma (CMF) is a relatively uncommon benign bone tumor of cartilaginous differentiation. The primary pitfall in the histopathologic diagnosis of CMF is confusion with a high-grade chondrosarcoma, owing to the atypical stellate and spindled cells set within a chondromyxoid background. CMF is particularly challenging to diagnose within the pelvis, where clinical suspicion for chondrosarcoma is high and benign lesions may grow to a large size to occupy the pelvic bones. Read More

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http://journals.sagepub.com/doi/10.1177/1066896918820446
Publisher Site
http://dx.doi.org/10.1177/1066896918820446DOI Listing
December 2018
4 Reads