5,534 results match your criteria International Journal of STD and AIDS[Journal]


Two cases of multidrug-resistant genitourinary Mycoplasma genitalium infection successfully eradicated with minocycline.

Int J STD AIDS 2019 Apr 10;30(5):512-514. Epub 2019 Jan 10.

1 Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Mycoplasma genitalium (MG) infection is a sexually transmitted infection that causes up to 25% of nongonococcal urethritis (NGU). MG strains carrying genetic markers of antimicrobial resistance that may affect treatment outcomes are increasingly recognized as a public health concern. We present two cases of persistent MG NGU with strains carrying both macrolide and quinolone resistance-associated mutations that were eradicated successfully by an extended course of minocycline. Read More

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http://dx.doi.org/10.1177/0956462418816757DOI Listing
April 2019
2 Reads

Superimposing incident sexually transmitted infections on HIV phylogram to investigate possible misclassification of men who have sex with men as heterosexuals in a cohort in Antwerp, Belgium.

Int J STD AIDS 2019 Apr 4;30(5):486-495. Epub 2019 Feb 4.

1 Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

In this study, we assessed if the superimposition of incident sexually transmitted infections (STIs) on HIV phylogenetic analyses could reveal possible sexual behaviour misclassifications in our HIV-infected population. HIV-1 sequences collected between 1997 and 2014 from 1169 individuals attending a HIV clinic in Antwerp, Belgium were analysed to infer a partial HIV transmission network. Individual demographic, clinical and laboratory data collected during routine HIV follow-up were used to compare clustered and non-clustered individuals using logistic regression analyses. Read More

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http://journals.sagepub.com/doi/10.1177/0956462418821752
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http://dx.doi.org/10.1177/0956462418821752DOI Listing
April 2019
1 Read

Efficacy and safety of abacavir/lamivudine with raltegravir in treatment-experienced and treatment-naïve patients with HIV-1 infection: an observational, retrospective, multi-centre study.

Int J STD AIDS 2019 Apr 10;30(5):467-471. Epub 2019 Jan 10.

1 Infectious Diseases Unit, G.B. Rossi University Hospital, Verona, Italy.

Raltegravir (RAL) is an HIV-1 integrase strand transfer inhibitor that is well established as a component of highly active antiretroviral therapy regimens for the treatment of adults living with human immunodeficiency virus (HIV), due to its high virological efficacy and good tolerability profile. To date, limited data are available on the use of RAL with abacavir/lamivudine (ABC/3TC). We investigated retrospectively 62 HIV-1 infected patients managed by three Italian Infectious Diseases Outpatient Departments, including 57 treatment-experienced patients and 5 treatment-naïve patients, treated with ABC/3TC plus RAL. Read More

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http://dx.doi.org/10.1177/0956462418817049DOI Listing

Bowenoid papulosis unveiling a rare cause of immunosuppression.

Int J STD AIDS 2019 Apr 4;30(5):522-525. Epub 2019 Feb 4.

Department of Dermatology & Venereology, Govt. Medical College, Thrissur, Kerala.

Bowenoid papulosis (BP) is a premalignant condition usually caused by oncogenic types of human papillomavirus (HPV) presenting clinically as warty genital papules. Adult T-cell leukaemia-lymphoma (ATLL) is a peripheral T-cell leukaemia-lymphoma caused by the retrovirus, human T-cell lymphotropic virus 1 (HTLV-1). We report a case of BP initially mistaken as genital warts; on detailed evaluation the patient had features of chronic immunosuppression. Read More

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http://dx.doi.org/10.1177/0956462418813057DOI Listing
April 2019
1 Read

Immune reconstitution inflammatory syndrome associated with secondary syphilis: dermatologic, neurologic and ophthalmologic compromise in an HIV patient.

Int J STD AIDS 2019 Apr 10;30(5):509-511. Epub 2019 Jan 10.

1 Servicio de Enfermedades Infecciosas y Tropicales. Hospital Nacional Dos de Mayo, Lima, Peru.

The presentation of syphilis as a manifestation of immune reconstitution inflammatory syndrome in patients with human immunodeficiency virus (HIV) infection is rare and can be associated with the varied clinical expression of unusual syphilitic manifestations. We report a case of immune reconstitution syndrome with dermatologic, ophthalmologic and neurologic compromise of secondary syphilis in a patient with HIV infection. Read More

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http://dx.doi.org/10.1177/0956462418813045DOI Listing

The association between gender and HIV viral suppression on third-line therapy in Zambia: a retrospective cohort study.

Int J STD AIDS 2019 Apr 10;30(5):453-459. Epub 2019 Jan 10.

1 Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.

Patient's gender may impact pharmacokinetics and play a role in viral suppression. Existing literature has focused on treatment-naïve patients and produced inconclusive results, often implicating differences in adherence as the driver of gender-based outcome differences. The present analysis assessed whether viral suppression on third-line HIV treatment among a closely followed population differs by gender. Read More

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http://journals.sagepub.com/doi/10.1177/0956462418817645
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http://dx.doi.org/10.1177/0956462418817645DOI Listing
April 2019
2 Reads

Cognitive function, depressive symptoms and syphilis in HIV-positive and HIV-negative individuals.

Int J STD AIDS 2019 Apr 10;30(5):440-446. Epub 2019 Jan 10.

1 Institute for Global Health, UCL, London, UK.

We evaluated associations between history of syphilis infection and both cognitive function and depressive symptoms in people living with HIV (PLHIV) and comparable HIV-negative controls. Syphilis serological tests, cognitive function and depression were assessed in PLHIV and controls participating in the Pharmacokinetic and Clinical Observations in People Over Fifty study. Cognitive test scores were converted to demographically adjusted T-scores (mean = 50, SD = 10) and then averaged to obtain a global T-score. Read More

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http://dx.doi.org/10.1177/0956462418817612DOI Listing
April 2019
1.037 Impact Factor

Incidence and risk factors for invasive pneumococcal disease in HIV-positive individuals in the era of highly active antiretroviral therapy.

Int J STD AIDS 2019 Apr 4;30(5):472-478. Epub 2019 Feb 4.

1 Department of Genitourinary Medicine and Infectious Diseases (GUIDE), St James's Hospital, Dublin, Ireland.

Invasive pneumococcal diseases (IPDs) remain a significant cause of morbidity and mortality in human immunodeficiency virus (HIV)-positive individuals despite the widespread use of highly active antiretroviral therapy (HAART) and availability of pneumococcal vaccines. The aim of this study was to measure temporal trends in incidence and risk factors for IPD (defined as culture of Streptococcus pneumoniae from blood, cerebrospinal fluid or both) in a cohort of HIV-positive patients attending an ambulatory HIV care centre in Dublin, Ireland over a 10-year period 2006-2015. Incidence of IPD was determined as events per 100,000 person-years' follow-up. Read More

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http://dx.doi.org/10.1177/0956462418817034DOI Listing
April 2019
1 Read

Ritonavir- or cobicistat-boosted antiretroviral therapy and direct oral anticoagulants: A case for apixaban.

Int J STD AIDS 2019 Apr 11:956462419832099. Epub 2019 Apr 11.

2 Indiana University Health, Indianapolis, IN, USA.

The potential for drug-drug interactions (DDIs) between direct oral anticoagulants and antiretroviral therapy (ART) is vast. Ritonavir and cobicistat are used as pharmacokinetic enhancers with either concurrent protease inhibitors or the integrase strand transfer inhibitor, elvitegravir, to optimize therapeutic concentrations by cytochrome P450 (CYP) inhibition. To date, only rivaroxaban and dabigatran have reported cases of use with ritonavir-boosted ART. Read More

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http://dx.doi.org/10.1177/0956462419832099DOI Listing

Unsupervised PrEP in routine practice: a new challenge?

Int J STD AIDS 2019 Apr 11:956462419828872. Epub 2019 Apr 11.

1 Service d'Immuno-hématologie Clinique, Aix Marseille Univ, APHM Sainte-Marguerite, Marseille, France.

Pre-exposure prophylaxis (PrEP) for the prevention of HIV infection with 300 mg daily tenofovir co-formulated with 200 mg emtricitabine is recommended as one prevention option for people who are at substantial risk of acquiring an HIV infection. We report the case of a 28-year-old man who has sex with men and who was referred to our unit for a primary HIV infection with positive p18, p24 and gp160 bands on Western blot analysis but with a low HIV plasma viral load. Although HIV misdiagnosis should always be considered in cases of atypical seroconversion pattern with a low viral burden, unsupervised PrEP should be systematically investigated. Read More

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http://dx.doi.org/10.1177/0956462419828872DOI Listing

University students' behaviours towards accessing sexual health information and treatment.

Int J STD AIDS 2019 Apr 8:956462419828866. Epub 2019 Apr 8.

3 Centre for Criminal Justice and Criminology, Swansea University, Swansea, UK.

Globally, it is widely recognised that young people (those under the age of 25 years) are at a higher risk of developing sexually transmitted infections (STIs). The majority of university students studying in the UK fall within this age bracket, and to help prevent such high incidence of STIs in this age group, it is essential that advice and treatment, if required, are obtained from reliable sources. This study sought to explore sources of sexual heath advice and treatment for students at Welsh universities (n = 3007). Read More

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http://dx.doi.org/10.1177/0956462419828866DOI Listing
April 2019
8 Reads

CD4/CD8 ratio improvement in HIV-1-infected patients receiving dual antiretroviral treatment.

Int J STD AIDS 2019 Apr 8:956462419834129. Epub 2019 Apr 8.

Department of Infectious Diseases, Ramón y Cajal Hospital, Madrid, Spain.

The CD4/CD8 ratio is an indirect marker of immune activation, immune senescence, and inflammation in HIV infection. We performed a prospective study of the CD4/CD8 ratio evolution in 245 virally-suppressed (median, 55 months) HIV-infected patients (29% females) who had switched to four dual antiretroviral regimens. At baseline, the median CD4/CD8 ratio was 0. Read More

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http://dx.doi.org/10.1177/0956462419834129DOI Listing
April 2019
2 Reads

Drug interaction after ritonavir discontinuation: considerations for antiretroviral therapy changes in renal transplant recipients.

Int J STD AIDS 2019 Apr 8:956462419829989. Epub 2019 Apr 8.

4 Division of Infectious Diseases, Saint Joseph's University Medical Center, Paterson, NJ, USA.

Organ transplantation among people living with human immunodeficiency virus (PLHIV) is increasing. Guidelines recommend any changes in antiretroviral therapy (ART) prior to transplantation, but there are limited data regarding ART changes post transplantation. We report a case where an ART switch from a protease inhibitor-based regimen to dolutegravir plus emtricitabine/tenofovir alafenamide in a renal transplant recipient led to subtherapeutic tacrolimus concentrations and an increased serum creatinine (SCr). Read More

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http://dx.doi.org/10.1177/0956462419829989DOI Listing
April 2019
2 Reads

HIV and HCV screening among trauma patients.

Int J STD AIDS 2019 Apr 8:956462419829590. Epub 2019 Apr 8.

4 Department of Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.

The purpose of this study was to develop a hepatitis C virus (HCV) and HIV screening program for patients evaluated by the trauma service and link to care. Patients were offered screening for HCV antibody and HIV. Demographics were collected on gender, race, age, and history of intravenous drug use. Read More

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http://journals.sagepub.com/doi/10.1177/0956462419829590
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http://dx.doi.org/10.1177/0956462419829590DOI Listing
April 2019
6 Reads

Health implications of sex trading characteristics in Long Beach, California, USA.

Int J STD AIDS 2019 Apr 8:956462419828138. Epub 2019 Apr 8.

6 Office of Research, Pacific University, Forest Grove, OR, USA.

This study examined the comparative health risk behaviors of women who (a) traded sex for money, (b) traded sex for drugs, (c) traded sex for both drugs and money, or (d) did not trade sex. Self-report data were collected from 2369 women who received services through HIV and sexually transmitted infection (STI) testing programs and a subset were tested for HIV, hepatitis B, hepatitis C, and syphilis. Results revealed those women who traded sex only for money used condoms, were tested for HIV, and received the HIV test results more often than the other women. Read More

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http://dx.doi.org/10.1177/0956462419828138DOI Listing
April 2019
1 Read

Evaluation of the BD MAX™ Vaginal Panel for the detection of vaginal infections in a sexual health service in the UK.

Authors:
Jackie Sherrard

Int J STD AIDS 2019 Mar 8;30(4):411-414. Epub 2019 Jan 8.

Department of Sexual Health, Buckinghamshire Healthcare NHS Trust, Wycombe General Hospital, Wycombe, UK.

The aim of this study is to compare the performance of the BD MAX™ Vaginal Panel (Becton, Dickinson and company, Franklin Lakes, NJ, USA) in the diagnosis of bacterial vaginosis (BV), candidiasis and trichomoniasis with current standard tests in a UK specialist sexual health service. Women with abnormal vaginal discharge attending the service who had not used douches or vaginal treatment in the preceding 48 hours had two vulvovaginal swabs taken: one for Chlamydia and gonorrhoea nucleic acid amplification test (NAAT) and one for testing on the BD MAX™ Vaginal Panel on the BD MAX System. Speculum examination was then performed and vaginal swabs taken for vaginal pH, and microscopy of vaginal secretions: Gram stain for Candida and BV using the Hay-Ison score and wet-mount for clue cells and Trichomonas vaginalis (TV). Read More

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http://dx.doi.org/10.1177/0956462418815284DOI Listing
March 2019
2 Reads

Optimizing enrollment methods: Lessons learned from an mHealth, pilot HIV prevention randomized controlled trial with sexual minority men.

Int J STD AIDS 2019 Mar 19:956462419831854. Epub 2019 Mar 19.

2 Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA.

Using data from eligible participants, we evaluated procedures of a multi-step enrollment process for an mHealth, pilot randomized controlled trial aimed to promote regular HIV testing among at-risk, diverse sexual minority men. Completion rates of eligible participants were calculated and characterized for these enrollment procedures. Among 3058 men who screened, 183 were eligible and 113 enrolled. Read More

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http://dx.doi.org/10.1177/0956462419831854DOI Listing

Exploring the spatial relationship between primary road distance to antenatal clinics and HIV prevalence in pregnant females of Lilongwe, Malawi.

Int J STD AIDS 2019 Mar 19:956462419830232. Epub 2019 Mar 19.

1 UNC Project, University of North Carolina at Chapel Hill, Lilongwe, Malawi.

While urbanization in a sub-Saharan African (SSA) context can lead to greater independence in women, various sociological, biological, and geographical factors in urban areas may keep women at a higher risk for HIV than men. Access to major roads during Malawi's transition into rapid urbanization may leave women disproportionately vulnerable to HIV infection. It is not well established whether women who report to health clinics closer to major roads have higher or lower levels of HIV. Read More

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http://dx.doi.org/10.1177/0956462419830232DOI Listing

Modeling economic and epidemiological impact of voluntary medical male circumcision among men who have sex with men in Beijing, China.

Int J STD AIDS 2019 Mar 19:956462419831859. Epub 2019 Mar 19.

3 School of Public Health, Yale University, New Haven, CT, USA.

Voluntary medical male circumcision (VMMC) among men who have sex with men (MSM) may protect against HIV acquisition. We conducted a series of analyses to assess if expanded VMMC might reduce HIV incidence among MSM effectively and economically. We used a deterministic compartmental model to project new HIV cases (2016-2026) under annual VMMC coverage rates (λ) ranging from 0. Read More

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http://dx.doi.org/10.1177/0956462419831859DOI Listing
March 2019
1 Read
1.037 Impact Factor

Risky sexual behavior and sexually transmitted infections among men who have sex with men and purchase sex attending an Israeli sexually transmitted infection clinic.

Int J STD AIDS 2019 Mar 19:956462419830856. Epub 2019 Mar 19.

3 Tel Aviv Department of Health, Tel Aviv, Israel.

Men who have sex with men (MSM) and purchase sex (MPS) are a sub-group potentially at high risk for acquiring and transmitting sexually transmitted infections (STIs). This is a hard-to-reach population resulting in a scarcity of studies covering the issue. This cross-sectional study aimed to assess the association between purchasing sex and high-risk behaviors related to HIV/STI transmission and appraise the STI prevalence among MSM. Read More

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http://dx.doi.org/10.1177/0956462419830856DOI Listing
March 2019
1 Read

Testing for genital mycoplasmas and ureaplasmas.

Int J STD AIDS 2019 Mar 4;30(3):310-311. Epub 2019 Feb 4.

5 School of Clinical Medicine, University of Cambridge, Cambridge, UK.

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http://journals.sagepub.com/doi/10.1177/0956462418820400
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http://dx.doi.org/10.1177/0956462418820400DOI Listing
March 2019
3 Reads

Corrigendum.

Authors:

Int J STD AIDS 2019 Mar 7:956462419838215. Epub 2019 Mar 7.

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http://dx.doi.org/10.1177/0956462419838215DOI Listing

Identifying risk factors for HIV-positive test results in walk-in and hospitalized patients in a Mexico City HIV clinic: a descriptive study.

Int J STD AIDS 2019 Feb 27:956462419828604. Epub 2019 Feb 27.

1 Departamento de Investigación en Enfermedades Infecciosas (CIENI), Instituto Nacional de Enfermedades Respiratorias (INER), Mexico City, Mexico.

The objective of this study was to analyze risk factors for HIV-positive tests in walk-in users and in hospitalized patients in a Mexico City hospital. We undertook a cross-sectional study based on routine HIV testing and counseling service data in adults undergoing an HIV test from January 2015 to July 2017. Multivariate analysis was performed to determine risk factors for walk-in and hospitalized patients. Read More

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http://dx.doi.org/10.1177/0956462419828604DOI Listing
February 2019

Factors associated with HIV testing among men who have sex with men in Guatemala City.

Int J STD AIDS 2019 Feb 27:956462419826393. Epub 2019 Feb 27.

6 Center on Gender Equity and Health, Division of Infectious Diseases and Global Public Health, School of Medicine, University of California, San Diego, La Jolla, CA, USA.

Although men who have sex with men (MSM) have the highest human immunodeficiency virus (HIV) prevalence in Guatemala, prevention efforts have been focused on other vulnerable populations. Respondent-driven sampling was used to recruit 444 MSM in Guatemala City to explore factors related to HIV testing among MSM. About 56% of participants reported HIV testing in the past 12 months, which was associated with a public MSM status (adjusted odds ratio (AOR) 2. Read More

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http://dx.doi.org/10.1177/0956462419826393DOI Listing
February 2019
4 Reads

Psoriasis in HIV infection: an update.

Int J STD AIDS 2019 Feb 27:956462419827673. Epub 2019 Feb 27.

1 Dermatology and Venereology Department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisboa, Portugal.

Psoriasis is a prevalent systemic immune-mediated disease with cutaneous manifestations. In HIV-infected patients, psoriasis may have a higher incidence, present atypical and more exuberant clinical features, and is frequently recalcitrant to treatment. Despite this aggravated severity, treatment options for psoriasis in HIV-infected individuals remain limited due to the risk of fatal immunosuppression associated with both classical immunosuppressants and new biological drugs. Read More

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http://journals.sagepub.com/doi/10.1177/0956462419827673
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http://dx.doi.org/10.1177/0956462419827673DOI Listing
February 2019
1 Read

Cervical cancer awareness and presence of abnormal cytology among HIV-infected women on antiretroviral therapy in rural Andhra Pradesh, India.

Int J STD AIDS 2019 Feb 27:956462419825950. Epub 2019 Feb 27.

1 Sue & Bill Gross School of Nursing, University of California, Irvine, CA, USA.

Cervical cancer is a leading cause of death among women in low- and middle-income countries, and women living with HIV are at high risk for cervical cancer. The objective of this study was to estimate the prevalence and correlates of cervical cancer and pre-cancer lesions and to examine cervical cancer knowledge among women living with HIV receiving antiretroviral therapy in rural Andhra Pradesh, India. We conducted cytology-based screening and administered a standardized questionnaire among 598 HIV-infected women. Read More

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http://dx.doi.org/10.1177/0956462419825950DOI Listing
February 2019
6 Reads
1.037 Impact Factor

Re: Chorioamnionitis in pregnancy: a comparative study of HIV-positive and HIV-negative parturients.

Int J STD AIDS 2019 Jan;30(1):101-102

1 Department of Obstetrics and Gynaecology, University of Jos/Jos University Teaching Hospital, Jos, Nigeria.

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http://dx.doi.org/10.1177/0956462418803820DOI Listing
January 2019
2 Reads
1.037 Impact Factor

Partner notification and contact tracing must accompany provider-initiated counselling and testing in population screening for HIV infection in Nigeria.

Int J STD AIDS 2019 Jan;30(1):99-100

3 Department of Internal Medicine, Niger Delta University Teaching Hospital, Okolobiri, Bayelsa State, Nigeria.

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http://dx.doi.org/10.1177/0956462418809293DOI Listing
January 2019
1.037 Impact Factor

Female sex workers in Kigali, Rwanda: a key population at risk of HIV, sexually transmitted infections, and unplanned pregnancy.

Int J STD AIDS 2019 Feb 6:956462418817050. Epub 2019 Feb 6.

1 Projet San Francisco, Rwanda Zambia HIV Research Group, Kigali, Rwanda.

Female sex workers (FSWs) were recruited from known hotspots in Kigali, Rwanda, and offered free, anonymous human immunodeficiency virus (HIV) counseling and testing, diagnosis and treatment of sexually transmitted infections (STIs) and long-acting reversible contraception (LARC). From September 2012 to March 2015, 1168 FSWs sought services, including 587 (50%) who were HIV-positive. More than 90% had previously tested for HIV, and 26% who reported previously testing negative had seroconverted. Read More

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http://dx.doi.org/10.1177/0956462418817050DOI Listing
February 2019
2 Reads

HIV encephalitis in a patient on antiretroviral therapy: a case report.

Int J STD AIDS 2019 Feb 5:956462418824905. Epub 2019 Feb 5.

3 Pomeranian Hospitals, Gdansk, Poland.

We present the case of a 52-year-old man with human immunodeficiency virus (HIV) encephalitis resulting from cerebrospinal fluid (CSF) viral escape, to illustrate therapeutic challenges in patients with emergent CSF genotypic HIV drug resistance. This case report highlights the usefulness of CSF HIV-resistance testing to guide antiretroviral therapy and treatment optimizing decisions. Read More

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http://dx.doi.org/10.1177/0956462418824905DOI Listing
February 2019
7 Reads

A case report of proctitis associated with Mycoplasma genitalium in a man who has sex with men.

Int J STD AIDS 2019 Feb 5:956462419825896. Epub 2019 Feb 5.

3 STI Unit Vall d'Hebron - Drassanes, Infectious Diseases Department, Hospital Vall d'Hebron, Barcelona, Spain.

Mycoplasma genitalium is an infection of increasing concern due to its potential to cause sequelae in the reproductive tract and the development of antimicrobial resistance. Its role as a cause of proctitis in people with high-risk sexual behaviour has not been properly defined yet but it seems to be less symptomatic than proctitis caused by Chlamydia trachomatis or Neisseria gonorrhoeae. We present a case of a man who has sex with men with proctitis associated with M. Read More

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http://dx.doi.org/10.1177/0956462419825896DOI Listing
February 2019
2 Reads

A case of late presentation of darunavir-related cholestatic hepatitis.

Int J STD AIDS 2019 Feb 5:956462419826723. Epub 2019 Feb 5.

2 Department of Gastroenterology, Tokuda Acibadem Hospital, Sofia, Bulgaria.

We report a case of darunavir-induced cholestatic hepatitis in a human immunodeficiency virus (HIV)-infected patient in the third year of his combined antiretroviral therapy. During the patient's monthly follow-up with regard to his HIV infection, elevated transaminase levels were detected. The patient was subsequently hospitalised at the AIDS and gastroenterology departments. Read More

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http://journals.sagepub.com/doi/10.1177/0956462419826723
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http://dx.doi.org/10.1177/0956462419826723DOI Listing
February 2019
10 Reads

The role of sexual risk behaviors on PrEP awareness and interest among men who have sex with men in Latin America.

Int J STD AIDS 2019 Feb 5:956462419825944. Epub 2019 Feb 5.

1 Department of Behavioral and Social Health Sciences, Brown University School of Public Health, Providence, RI, USA.

In Latin America, men who have sex with men (MSM) remain disproportionately impacted by HIV. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention tool and has been FDA approved in the United States since 2012, but no Latin American state, with the recent exception of Brazil, has implemented PrEP guidelines. We carried out a multinational online survey of MSM in Latin America (n = 22698) in 2012 to assess whether MSM at highest risk of HIV acquisition (i. Read More

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http://dx.doi.org/10.1177/0956462419825944DOI Listing
February 2019
9 Reads
1.037 Impact Factor

Diagnostic determination of Norovirus infection as one of the major causes of infectious diarrhea in HIV patients using a multiplex polymerase chain reaction assay.

Int J STD AIDS 2019 Feb 5:956462418824912. Epub 2019 Feb 5.

2 Clinical Laboratory of Beijing Ditan Hospital, Capital Medical University, Beijing, China.

Although infectious diarrhea is one of the most common complications in human immunodeficiency virus (HIV)-infected patients, robust diagnostic methods for determining potential pathogens are still limited in the clinic. Norovirus, a type of calicivirus, has been shown to be the most common cause of gastroenteritis. Here, we used multiplex polymerase chain reaction as a diagnostic tool to verify Norovirus as the diarrhea-related pathogen in HIV-infected patients with unknown etiological information. Read More

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http://journals.sagepub.com/doi/10.1177/0956462418824912
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http://dx.doi.org/10.1177/0956462418824912DOI Listing
February 2019
12 Reads

Failure of syndromic management due to drug-resistant Mycoplasma genitalium infection in South Africa: a case report.

Int J STD AIDS 2019 Apr 4;30(5):519-521. Epub 2019 Feb 4.

1 Department of Medical Microbiology, University of Pretoria, Pretoria, South Africa.

We report a case of management failure of male urethritis syndrome due to macrolide-resistant Mycoplasma genitalium in South Africa. We detected mutations in 23S rRNA and one of the quinolone resistance-determining regions. This report confirms that drug-resistant M. Read More

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http://dx.doi.org/10.1177/0956462418820745DOI Listing
April 2019
2 Reads

Validity of hemoglobin A1c for diagnosing diabetes among people with and without HIV in Uganda.

Int J STD AIDS 2019 Apr 4;30(5):479-485. Epub 2019 Feb 4.

4 Massachusetts General Hospital, Boston, MA, USA.

Sub-Saharan Africa (SSA) is facing a growing co-epidemic of chronic HIV infection and diabetes. Hemoglobin A1c (A1c) may underestimate glycemia among people living with HIV (PLWH). We estimated the validity of A1c to diagnose diabetes among PLWH and HIV-uninfected persons in rural Uganda. Read More

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http://dx.doi.org/10.1177/0956462418823406DOI Listing

Lymphogranuloma venereum presenting as penile ulcer in two HIV-negative gay men.

Int J STD AIDS 2019 Apr 4;30(5):515-518. Epub 2019 Feb 4.

3 RPA Sexual Health, Sydney Local Health District, Camperdown, Australia.

An epidemic of lymphogranuloma venereum among men who have sex with men (MSM) has persisted in Australia for over a decade and virtually all diagnoses are made from rectal samples. We discuss two cases of human immunodeficiency virus-negative MSM who presented with a penile ulcer. The diagnosis can be made by ensuring a swab of any such ulcer is tested for Chlamydia trachomatis. Read More

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http://dx.doi.org/10.1177/0956462418821579DOI Listing
April 2019
1 Read

HIV-positive in the darkness of a correctional facility: more vulnerable and less treated.

Int J STD AIDS 2019 Apr 10;30(5):460-466. Epub 2019 Jan 10.

1 COREVIH Guyane, Centre Hospitalier André Rosemon, Cayenne, France.

In French Guiana, 4.5-5.0% of HIV-infected persons experienced an incarceration between 2007 and 2013. Read More

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http://dx.doi.org/10.1177/0956462418816452DOI Listing
April 2019
1 Read

Nodulo-ulcerative and erythrodermic secondary syphilis in human immunodeficiency virus-infected individuals.

Int J STD AIDS 2019 Apr 10;30(5):505-508. Epub 2019 Jan 10.

Department of Dermatology, Topiwala National Medical College & BYL Nair Charitable Hospital, Mumbai, India.

Syphilis and human immunodeficiency virus (HIV) infections are both transmitted sexually. Co-infection of HIV and syphilis alters the course of both diseases. Clinical presentation of syphilis in patients of HIV may be atypical. Read More

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http://dx.doi.org/10.1177/0956462418815310DOI Listing
April 2019
13 Reads

Tenofovir disoproxil fumarate/emtricitabine is associated with a higher risk of hypocalcemia compared to abacavir/lamivudine - results from a German cohort study.

Int J STD AIDS 2019 Apr 10;30(5):447-452. Epub 2019 Jan 10.

3 MUC Research, München, Germany.

Hyperparathyroidism has been described in people living with HIV undergoing tenofovir disoproxil fumarate (TDF)-containing antiretroviral therapy (ART), but differences in calcium levels have never been investigated in detail. We aimed to compare the prevalence of hypocalcemia between patients with and without TDF-containing ART. The patients and methods were a retrospective cohort study in HIV-infected adult patients receiving dolutegravir and either abacavir (ABC)/lamivudine (3TC) or TDF/emtricitabine in a single center in Munich, Germany. Read More

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http://dx.doi.org/10.1177/0956462418815022DOI Listing
April 2019
2 Reads

Why we need pre-exposure prophylaxis: incident HIV and syphilis among men, and transgender women, who have sex with men, Bangkok, Thailand, 2005-2015.

Int J STD AIDS 2019 Apr 9;30(5):430-439. Epub 2019 Jan 9.

1 Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.

We describe incident human immunodeficiency virus (HIV) and syphilis trends in men who have sex with men (MSM) and transgender women (TGW) presenting for HIV voluntary counseling and testing (VCT) services and sexually transmitted infection (STI) management at the Silom Community Clinic, Bangkok, Thailand. Clients underwent rapid HIV testing and syphilis rapid plasma reagin (RPR) testing. For incidence analysis, we included clients with >1 follow-up visit. Read More

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http://dx.doi.org/10.1177/0956462418814994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474786PMC
April 2019
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Point-of-care diagnostics: needs of African health care workers and their role combating global antimicrobial resistance.

Int J STD AIDS 2019 Mar 9;30(4):404-410. Epub 2019 Jan 9.

5 Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Point-of-care tests (POCTs) offer the opportunity for increased diagnostic capacity in resource-limited settings, where there is lack of electricity, technical capacity, reagents, and infrastructure. Understanding how POCTs are currently used and determining what health care workers (HCWs) need is key to development of appropriate tests. In 2016, we undertook an email survey of 7584 HCWs who had received training at the Infectious Diseases Institute, Uganda, in a wide variety of courses. Read More

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http://journals.sagepub.com/doi/10.1177/0956462418807112
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http://dx.doi.org/10.1177/0956462418807112DOI Listing
March 2019
4 Reads

Trichomonas vaginalis virus: a review of the literature.

Int J STD AIDS 2019 Apr 9;30(5):496-504. Epub 2019 Jan 9.

1 Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.

Trichomonas vaginalis (TV) is a parasitic protozoan responsible for the sexually transmitted infection trichomoniasis. Trichomonas vaginalis virus (TVV) is a nonsegmented, 4.5-5 kbp, double-stranded RNA virus, from the Totiviridae family, which inhabits TV. Read More

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http://dx.doi.org/10.1177/0956462418809767DOI Listing
April 2019
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Enhanced surveillance of syphilis cases among men who have sex with men in London, October 2016-January 2017.

Int J STD AIDS 2019 Apr 8;30(5):422-429. Epub 2019 Jan 8.

1 Field Service, PHE, London, UK.

Syphilis rates have been increasing in men who have sex with men (MSM) in London. To describe risk behaviour and refine public health interventions, we conducted prospective enhanced surveillance of new syphilis cases in MSM attending selected London sexual health clinics (SHCs) between October 2016 and January 2017. Sexual health advisors (SHAs) completed 107 questionnaires. Read More

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http://journals.sagepub.com/doi/10.1177/0956462418814998
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http://dx.doi.org/10.1177/0956462418814998DOI Listing
April 2019
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Behavioral characteristics and their association with syphilis seroprevalence among a cohort of young Black men who have sex with men.

Int J STD AIDS 2019 Mar 8;30(4):396-403. Epub 2019 Jan 8.

2 Department of Public Health Sciences, University of Chicago, Chicago, IL, USA.

The objective of this study was to describe the sociodemographic characteristics and behavioral factors that are associated with syphilis seroprevalence in a cohort of young Black men who have sex with men (YBMSM) in Chicago, USA (n = 606). The weighted syphilis seroprevalence in the study population was 29.2% (95% CI 23. Read More

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http://dx.doi.org/10.1177/0956462418816449DOI Listing
March 2019
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Reasons for delayed antiretroviral therapy (ART) initiation in the era of early ART initiation guidelines: a retrospective service evaluation.

Int J STD AIDS 2019 Mar 8;30(4):415-418. Epub 2019 Jan 8.

3 St Mary's Hospital and Imperial College, London, UK.

Following changes in national antiretroviral therapy (ART) guidelines removing the CD4 threshold for initiation of ART, we evaluated the time to ART initiation and reasons for delayed or non-initiation. A retrospective notes review of 292 newly diagnosed HIV-positive individuals attending two London clinics between August 2015 and December 2016 was performed. Two hundred and fifty-four of 292 (87%) individuals started ART. Read More

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http://journals.sagepub.com/doi/10.1177/0956462418814985
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http://dx.doi.org/10.1177/0956462418814985DOI Listing
March 2019
25 Reads

Prevalence and determinants of unprotected sex in intimate partnerships of men who inject drugs: findings from a prospective intervention study.

Int J STD AIDS 2019 Mar 12;30(4):386-395. Epub 2018 Dec 12.

1 Department of Obstetrics and Gynaecology, International Centre for Reproductive Health, Ghent University, Ghent, Belgium.

Unprotected sex, common among people who inject drugs, puts them and their partners at risk of sexually transmitted infections including human immunodeficiency virus (HIV). This analysis assesses the changes in sexual risk behavior with regular female partners (RFPs), among married men who inject drugs, before and after implementation of a HIV prevention intervention, and identifies correlates of unprotected sex. People who inject drugs (PWID) were assessed at three points: baseline, preintervention follow-up visit (FV)1, and postintervention FV2. Read More

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http://dx.doi.org/10.1177/0956462418802142DOI Listing
March 2019
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Characterizing HIV risk among cisgender men in Latin America who report transgender women as sexual partners: HIV risk in Latin America men.

Int J STD AIDS 2019 Mar 11;30(4):378-385. Epub 2018 Dec 11.

3 The Fenway Institute, Fenway Health, Boston, MA, USA.

Cisgender men (CM) who report transgender women (TW) as sexual partners are an understudied population in the HIV epidemic in Latin America. The current study sought to characterize this group in a 2012 cross-sectional online survey of Latin American CM who were members of a sexual networking website for men who have sex with men (N = 11,847). Multivariable logistic regression models were fit to estimate demographic, behavioral, and psychosocial correlates of having a TW sexual partner and engaging in condomless sex. Read More

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http://dx.doi.org/10.1177/0956462418802687DOI Listing
March 2019
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Widespread use of herbal medicines by people living with human immunodeficiency virus and contamination of herbal medicines with antiretrovirals in Nigeria.

Int J STD AIDS 2019 Mar 30;30(4):371-377. Epub 2018 Nov 30.

1 Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

Herbal medication use amongst people living with human immunodeficiency virus (PLWH) is widespread and understudied. This study aimed to evaluate the prevalence of herbal medicine use amongst PLWH and possible contamination with antiretrovirals (ARVs). Countrywide collection of herbal samples sold by street vendors in Nigeria for the following indications: human immunodeficiency virus (HIV), acquired immune deficiency syndrome, fever and general weakness. Read More

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http://dx.doi.org/10.1177/0956462418809749DOI Listing
March 2019
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Response to the recently published UK National Guideline on the Sexual Health Care of Men who Have Sex with Men.

Int J STD AIDS 2019 Feb 30;30(2):204-205. Epub 2018 Nov 30.

Department of Genitourinary Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2GW, UK.

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http://dx.doi.org/10.1177/0956462418813070DOI Listing
February 2019
1 Read