1,725 results match your criteria International Journal of Rheumatic Diseases[Journal]


Efficacious transition from reference infliximab to biosimilar infliximab in clinical practice.

Int J Rheum Dis 2019 Feb 14. Epub 2019 Feb 14.

Amsterdam Rheumatology and Immunology Center, Reade, Rheumatology, Amsterdam, The Netherlands.

Objectives: To evaluate the transition from reference infliximab Remicade to biosimilar Remsima in patients with rheumatoid arthritis (RA) or psoriatic arthritis (PsA).

Methods: Patients were informed through a letter about the transition to a biosimilar and were subsequently contacted for possible additional questions and whether they agreed upon the transition. Once agreed, Remsima was administered at the same dosage and interval as previous treatment with Remicade. Read More

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http://dx.doi.org/10.1111/1756-185X.13512DOI Listing
February 2019

Real-world effectiveness and safety of rituximab in the treatment of rheumatoid arthritis: A single-center experience in Taiwan.

Int J Rheum Dis 2019 Feb 13. Epub 2019 Feb 13.

Division of Allergy, Immunology and Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Aim: To assess the real-world effectiveness and safety of rituximab (RTX) at 24 months in patients with established rheumatoid arthritis (RA) and to identify predictors of low disease activity/remission and a good European League Against Rheumatism (EULAR) response.

Methods: Seventy RTX-treated RA patients were enrolled. Predictors for low disease activity/remission and a good EULAR response at 24 months were identified by multivariate analyses. Read More

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http://dx.doi.org/10.1111/1756-185X.13511DOI Listing
February 2019

Estrogen reverses nicotine-induced inflammation in chondrocytes via reducing the degradation of ECM.

Int J Rheum Dis 2019 Feb 11. Epub 2019 Feb 11.

Laboratory Animal Center of Instrumental Analysis Center, Shanghai Jiao Tong University, Shanghai, China.

Problem: Osteoarthritis (OA) is a chronic disease with a very high incidence and the pathology of which is quite complex. Epidemiological investigation showed that OA may be related to smoking and estrogen levels, but there are few studies focused on the cross-effect of these two factors. This research aims to investigate the molecular mechanism of nicotine and estrogen effects on chondrocytes to study the effect of smoking on the incidence of osteoarthritis in women. Read More

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http://dx.doi.org/10.1111/1756-185X.13476DOI Listing
February 2019
2 Reads

Pulmonary arterial hypertension in systemic lupus erythematosus based on a CSTAR-PAH study: Baseline characteristics and risk factors.

Int J Rheum Dis 2019 Feb 11. Epub 2019 Feb 11.

Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

Aim: Pulmonary arterial hypertension (PAH) is a complex and devastating complication of systemic lupus erythematosus (SLE). We sought to describe the baseline characteristics of right heart catheterization (RHC)-confirmed SLE-associated PAH and identify risk factors for PAH in SLE patients.

Methods: A multicenter, cross-sectional study was conducted using the Chinese SLE Treatment and Research group (CSTAR) registry. Read More

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http://doi.wiley.com/10.1111/1756-185X.13478
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http://dx.doi.org/10.1111/1756-185X.13478DOI Listing
February 2019
3 Reads
1.771 Impact Factor

Susceptibility to ERAP1 gene single nucleotide polymorphism modulates the inflammatory cytokine setting in ankylosing spondylitis.

Int J Rheum Dis 2019 Feb 10. Epub 2019 Feb 10.

Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Aim: To evaluate the association of ERAP1 gene single nucleotide polymorphisms (SNPs) with the risk of ankylosing spondylitis (AS) and their role in modulation of the inflammatory interleukin (IL)-17/IL-23 axis in the disease.

Methods: For genotyping, 190 AS cases and 190 healthy controls were enrolled. After DNA extraction, all the subjects were genotyped for rs17482078, rs469876, and rs27038 polymorphisms using single specific primer polymerase chain reaction (PCR) assay. Read More

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http://dx.doi.org/10.1111/1756-185X.13494DOI Listing
February 2019
1 Read

Evaluation of disease chronicity by bone marrow fat fraction using sacroiliac joint magnetic resonance imaging in patients with spondyloarthritis: A retrospective study.

Int J Rheum Dis 2019 Feb 10. Epub 2019 Feb 10.

Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.

Aim: This study investigated the use of fat fraction (FF) measurements in the sacroiliac (SI) joint to determine radiologic progression in patients with spondyloarthritis (SpA).

Method: A total of 138 patients who underwent pelvic magnetic resonance imaging (MRI) between September 2014 and March 2015 were retrospectively evaluated. The FF based upon fat deposition (%) using fat signaling on T1 and T2 weighted images in the sacroiliac joint was quantified using a 6-echo variant of the modified Dixon technique. Read More

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http://dx.doi.org/10.1111/1756-185X.13485DOI Listing
February 2019
2 Reads

Pulse corticosteroids in treatment of rheumatic disease concomitant with cytomegalovirus infection.

Int J Rheum Dis 2019 Feb 10. Epub 2019 Feb 10.

Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis (BZ0135), Peking-Tsinghua Center for Life Sciences, Beijing, China.

Aim: To investigate the impact of corticosteroids on the outcome of antiviral therapy in rheumatic patients with cytomegalovirus (CMV)-emia.

Method: Sixty-two patients with rheumatic disease complicated by CMV infection from 2011 to 2014 were retrospectively analyzed.

Results: Fifty-five of 62 patients were diagnosed with CMV-DNAemia. Read More

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http://dx.doi.org/10.1111/1756-185X.13467DOI Listing
February 2019

Can Sjögren's syndrome diagnosis and evaluation be stretched by elastography?

Int J Rheum Dis 2019 Feb;22(2):172-174

Department of Internal Medicine, Clinical Ultrasound and Training Services, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1111/1756-185X.13492DOI Listing
February 2019
1 Read

APLAR Matters.

Authors:

Int J Rheum Dis 2019 Feb;22(2):331-332

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http://dx.doi.org/10.1111/1756-185X.13532DOI Listing
February 2019
1 Read

Diagnostic value of anti-citrullinated fibrinogen antibody in rheumatoid arthritis: A meta-analysis.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Anhui Province Key Laboratory of Major Autoimmune Diseases, Hefei, Anhui, China.

Aim: To evaluate the overall diagnostic value of anti-citrullinated fibrinogen (ACF) antibody in patients with rheumatoid arthritis (RA).

Methods: Published studies were systematically retrieved from PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), Wan Fang, China Biology Medicine (CBM) disc, and Chinese VIP databases. QUADAS-2 tool was applied to evaluate the quality of eligible studies. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1756-185X.13
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http://dx.doi.org/10.1111/1756-185X.13477DOI Listing
February 2019
3 Reads
1.771 Impact Factor

Validation of algorithms to identify knee osteoarthritis patients in the claims database.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea.

Background: To identify knee osteoarthritis (OA) patients among OA patients in the claims database.

Methods: All patients with OA diagnostic codes for any sites (M15 to M19) in 2014 were recruited from a single academic referral hospital. After excluding patients who had inflammatory arthritis or were less than 50 years of age, we identified data for the overall OA population. Read More

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http://dx.doi.org/10.1111/1756-185X.13470DOI Listing
February 2019

Effects of vitamin D on disease activity and serum interleukin-6 in rheumatoid arthritis.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Division of Rheumatology, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Aim: Vitamin D or 25(OH)D may have a potential role in rheumatoid arthritis (RA) pathogenesis by inhibiting the expression of pro-inflammatory cytokines including interleukin-6 (IL-6). The aim of this study is to determine the clinical factors of vitamin D deficiency in multi-ethnic Malaysian RA patients and its association with disease activity, functional disability and serum IL-6 levels.

Method: One hundred RA patients and 50 healthy controls, sex- and age-matched, were recruited. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1756-185X.13
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http://dx.doi.org/10.1111/1756-185X.13484DOI Listing
February 2019
9 Reads

Who seeks physiotherapy or exercise treatment for hip and knee osteoarthritis? A cross-sectional analysis of the english longitudinal study of age cohort.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

School of Health & Social Care, London South Bank University, London, UK.

Objectives: To determine the characteristics of individuals with hip and/or knee osteoarthritis who are recommended to seek physiotherapy or exercise treatment, and to explore which people are more or less likely to follow such recommendations.

Methods: All data were obtained from Wave 4 of the English Longitudinal Study of Ageing (ELSA) cohort (2008-2009), a prospectively collected community-based dataset. Eligibility was justified by a patient-reported diagnosis of hip and/or knee osteoarthritis with a visual analog scale (VAS) pain score of 1 or above. Read More

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http://dx.doi.org/10.1111/1756-185X.13480DOI Listing
February 2019
1 Read

Serum miR-214 as a novel biomarker for ankylosing spondylitis.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Department of Rheumatology, Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju, Korea.

Objective: Serum microRNA (miR) in ankylosing spondylitis (AS) patients has been rarely identified. The objective of this study was to find AS-specific miR in sera of patients with AS.

Methods: Total RNAs were isolated from whole sera of patients with AS, patients with rheumatoid arthritis (RA), and healthy controls (HC) using miRNeasy Serum/Plasma Kit. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1756-185X.13
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http://dx.doi.org/10.1111/1756-185X.13475DOI Listing
February 2019
5 Reads

Impact of hepatitis C treatment on pain intensity, prescription opioid use and arthritis.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Oregon Health and Science University, Portland, Oregon.

Objective: To assess the impact of direct acting anti-viral (DAA) therapy for hepatitis C virus (HCV) infection on changes in pain intensity and prescription opioid use among Veterans.

Methods: We conducted a retrospective cohort study of Veterans with HCV who were seen in a rheumatology clinic at least once while receiving DAA therapy between January 1, 2010 and December 31st 2016. Demographic characteristics, HCV status, HCV treatment characteristics, numeric rating scale (NRS) pain scores and opioid prescription data were extracted from the electronic medical record. Read More

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http://dx.doi.org/10.1111/1756-185X.13479DOI Listing
February 2019
1 Read

Apoptosis in patients with primary antiphospholipid antibody syndrome.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Translational Medicine Laboratory, Rheumatic Diseases Research Center, China Medical University Hospital, Taichung, Taiwan.

Aim: Dysregulated apoptosis has been implicated in autoimmune diseases. In the present study, we investigated the apoptosis-related cytokines and apoptosis in patients with primary antiphospholipid syndrome (pAPS).

Method: We prospectively recruited 12 pAPS patients, 17 antiphospholipid antibody (APA)-positive systemic lupus erythematosus (SLE) patients without APS manifestations (APA SLE), 13 SLE patients with secondary APS (APS SLE) and 10 healthy controls (HCs). Read More

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http://dx.doi.org/10.1111/1756-185X.13468DOI Listing
February 2019
1 Read

HLA-B27 prevalence in axial spondyloarthritis patients and in blood donors in a Lebanese population: Results from a nationwide study.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Rheumazentrum Ruhrgebiet, Herne, Germany.

Aim: To calculate the prevalence of human leukocyte antigen (HLA)-B27 in axial spondyloarthritis patients (axSpA) compared to blood donors (BD) in Lebanon, to identify the clinical and radiological findings associated with HLA-B27 and to estimate the proportion of patients fulfilling the clinical arm of the Assessment of the Spondyloarthritis International Association (ASAS) criteria.

Method: Consecutive Lebanese adult axSpA patients fulfilling the ASAS classification criteria were included from 12 rheumatology clinics across Lebanon. BD served as controls. Read More

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http://dx.doi.org/10.1111/1756-185X.13487DOI Listing
February 2019
1 Read

Prognostic nutritional index is associated with disease severity and relapse in ANCA-associated vasculitis.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.

Aim: The prognostic nutritional index (PNI), calculated by serum albumin and peripheral blood lymphocyte count, is considered to reflect immune-related nutritional status. In this study, we first investigated the clinical significance of PNI in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV).

Method: Medical records of 160 patients classified as AAV from October 2000 to September 2017 were reviewed. Read More

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http://dx.doi.org/10.1111/1756-185X.13507DOI Listing
February 2019

The association between vitamin D level and Sjögren's syndrome: A meta-analysis.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1111/1756-185X.13474DOI Listing
February 2019
1 Read

A low perfusion-metabolic mismatch in Tl and I-BMIPP scintigraphy predicts poor prognosis in systemic sclerosis patients with asymptomatic cardiac involvement.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.

Aim: This study investigated the prognostic factors of cardiac death or cardiac failure using cardiac scintigraphy, echocardiography (UCG), and magnetic resonance imaging (MRI) in asymptomatic systemic sclerosis (SSc) patients.

Methods: We retrospectively evaluated SSc patients who had undergone cardiac scintigraphy using thallium ( Tl) and I-β-methyl-P-iodophenyl-pentadecanoic acid ( I-BMIPP), UCG, and cardiac MRI. We calculated the mismatch score in scintigraphy by subtracting the uptake of I-BMIPP from that of Tl. Read More

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http://dx.doi.org/10.1111/1756-185X.13508DOI Listing
February 2019
2 Reads

Clinical significance of positive anti-neutrophil cytoplasmic antibodies without evidence of anti-neutrophil cytoplasmic antibodies-associated vasculitis.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Department of Internal Medicine F and the Rheumatology Unit, The Chaim Sheba Medical Center, Ramat Gan, Israel.

Aim: Anti-neutrophil cytoplasmic antibodies (ANCA) have a role in the diagnostic workup of ANCA-associated vasculitis. However, the clinical significance of positive ANCA in the absence of vasculitis is yet to be determined. Therefore, we sought to investigate the clinical spectrum and rate of patients with a positive ANCA without evidence of vasculitis. Read More

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http://dx.doi.org/10.1111/1756-185X.13483DOI Listing
February 2019

Prevalence and associated factors of small intestinal bacterial overgrowth among systemic sclerosis patients.

Int J Rheum Dis 2019 Feb 6. Epub 2019 Feb 6.

Faculty of Medicine, Division of Allergy-Immunology-Rheumatology, Department of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Background: Small intestinal bacterial overgrowth (SIBO) results in nutrient malabsorption and malnutrition, thereby increasing the morbidity and mortality in systemic sclerosis (SSc) patients.

Objectives: To evaluate the prevalence and associated factors of SIBO in SSc patients.

Method: A cross-sectional study was conducted between July 2015 and January 2016 in SSc patients over 18, using the glucose H /CH breath test to evaluate SIBO. Read More

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http://dx.doi.org/10.1111/1756-185X.13495DOI Listing
February 2019
1 Read

Recent advances in the management of Takayasu arteritis.

Int J Rheum Dis 2019 Jan;22 Suppl 1:60-68

Department of Clinical Immunology & Rheumatology, Christian Medical College Hospital, Vellore, India.

Takayasu arteritis (TA) is a challenging large vessel vasculitis to treat. Distinguishing disease activity from vascular damage is difficult, often relying on clinician judgement aided by composite clinical disease activity indices with angiographic evidence of vessel wall thickening or vessel wall hypermetabolism demonstrable on positron emission tomography computerized tomography (PET CT). Glucocorticoids form the mainstay of remission induction. Read More

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http://dx.doi.org/10.1111/1756-185X.13285DOI Listing
January 2019
2 Reads
1.771 Impact Factor

Vasculitis special issue.

Authors:
Debashish Danda

Int J Rheum Dis 2019 Jan;22 Suppl 1

Department of Clinical Immunology and Rheumatology, Christian Medical College and Hospital, Vellore, TN, India.

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http://dx.doi.org/10.1111/1756-185X.13466DOI Listing
January 2019
1.771 Impact Factor

Vasculitis research: Moving east.

Authors:
Aman Sharma

Int J Rheum Dis 2019 Jan;22 Suppl 1:6-7

Department of Internal Medicine, Clinical Immunology and Rheumatology Services, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1111/1756-185X.13368DOI Listing
January 2019

A tribute to Paul Bacon.

Int J Rheum Dis 2019 Jan;22 Suppl 1:8-9

S.G.P.G.I.M.S, Lucknow, India.

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http://dx.doi.org/10.1111/1756-185X.13369DOI Listing
January 2019

Takayasu arteritis: A distinct syndrome of large vessel vasculitis: A view point by late Professor Paul Bacon.

Authors:
Ramnath Misra

Int J Rheum Dis 2019 Jan;22 Suppl 1:49-52

Clinical Immunology and Rheumatology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.

Takayasu arteritis (TA), despite being classified as a large vessel vasculitis, has distinct genetic, pathological and clinical features as compared to giant cell arteritis. It is a rare disease seen more commonly in Asian countries. The challenge lies in assessing the degree of inflammation in a narrowed vessel and immunosuppressive therapy improves inflammatory features but is unable to open up an occluded vessel. Read More

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http://dx.doi.org/10.1111/1756-185X.13383DOI Listing
January 2019
1 Read

Imaging in small and medium vessel vasculitis.

Int J Rheum Dis 2019 Jan;22 Suppl 1:78-85

Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Vasculitis includes a group of disorders characterized by inflammation of the vessel wall and classified based on the diameter of the predominantly involved vessels. Granulomatosis with polyangiitis, microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis and Henoch-Schonlein purpura are the important entities in the small vessel vasculitis group, while polyarteritis nodosa and Kawasaki disease represent the medium vessel vasculitis group. The clinical manifestations may be non-specific and there may be considerable overlap with the other disorders. Read More

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http://dx.doi.org/10.1111/1756-185X.13390DOI Listing
January 2019
1 Read

Prakash K. Pispati.

Authors:
Rohini Handa

Int J Rheum Dis 2019 Jan;22(1):158-159

Indian College of Rheumatology, India.

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http://dx.doi.org/10.1111/1756-185X.13481DOI Listing
January 2019

Similar and mimics: Latin America biosimilar regulations.

Int J Rheum Dis 2019 Jan;22(1):6-8

Organización Medica de Investigación, Buenos Aires, Argentina.

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http://dx.doi.org/10.1111/1756-185X.13461DOI Listing
January 2019

Letters from the outgoing and incoming Editor in Chief.

Int J Rheum Dis 2018 Dec;21(12):2056

Sydney, Australia.

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http://dx.doi.org/10.1111/1756-185X.13471DOI Listing
December 2018
1.771 Impact Factor

Behçet's disease.

Int J Rheum Dis 2018 Dec;21(12):2057-2058

Rheumatology Research Center, Iran's National Elites Foundation (Chair Behçet's Disease), Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1111/1756-185X.13465DOI Listing
December 2018
1 Read

The challenges of early diagnosis and therapeutic prediction in rheumatoid arthritis.

Int J Rheum Dis 2018 Dec;21(12):2059-2062

Department of Rheumatology and Immunology, Peking University Third Hospital, Beijing, China.

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http://dx.doi.org/10.1111/1756-185X.13459DOI Listing
December 2018
1 Read

Clinical outcomes of patients with active rheumatoid arthritis with normal acute phase reactant values.

Int J Rheum Dis 2019 Jan 24. Epub 2019 Jan 24.

Division of Rheumatology, Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.

Aim: Despite high clinical disease activity, some patients with active rheumatoid arthritis (RA) have normal acute phase reactant (APR) values. This study aimed to determine the clinical outcomes of active RA patients with normal APR values.

Method: Of 5376 patients with RA enrolled in the Korean observational study network for arthritis (KORONA) registry, 400 patients with disease duration of <2 years who had Clinical Disease Activity Index (CDAI) score of >2. Read More

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http://doi.wiley.com/10.1111/1756-185X.13469
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http://dx.doi.org/10.1111/1756-185X.13469DOI Listing
January 2019
7 Reads

Iguratimod ameliorates bleomycin-induced alveolar inflammation and pulmonary fibrosis in mice by suppressing expression of matrix metalloproteinase-9.

Int J Rheum Dis 2019 Jan 21. Epub 2019 Jan 21.

Department of Rheumatology, Beijing Hospital, National Center of Gerontology, Beijing, China.

Aim: To investigate the potential therapeutic efficacy of iguratimod (IGU) on bleomycin (BLM)-induced pulmonary fibrosis in mice.

Methods: A total of 75 C57BL/6 mice were randomly and evenly divided into control group, BLM (5 mg/kg) group, BLM + IGU (90 mg/kg) group, BLM + methylprednisolone (MP, 10 mg/kg) group and BLM + pirfenidone (PF, 100 mg/kg) group. The mice were sacrificed on day 7, 14 and 28. Read More

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http://dx.doi.org/10.1111/1756-185X.13463DOI Listing
January 2019

Disease activity and functional status associated with health-related quality of life and patient-acceptable symptom state in patients with psoriatic arthritis in Thailand: A cross-sectional study.

Int J Rheum Dis 2019 Jan 21. Epub 2019 Jan 21.

Division of Rheumatology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Aim: To identify factors associated with the EuroQol-5 Dimensions-5 levels (EQ-5D-5L) and patient acceptable symptom state (PASS) and to estimate health utility (HU) in Thai patients with psoriatic arthritis (PsA).

Methods: A cross-sectional study of consecutive PsA patients visiting Siriraj Hospital was performed between 31 May, 2012 and 31 March, 2016. Data of patient demographics, HU outcomes (Thai EQ-5D-5L), disease activity (Disease Activity Index for Psoriatic Arthritis [DAPSA], the Clinical DAPSA [cDAPSA], the minimal disease activity [MDA]), and the Health Assessment Questionnaire (HAQ) were collected. Read More

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http://doi.wiley.com/10.1111/1756-185X.13473
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http://dx.doi.org/10.1111/1756-185X.13473DOI Listing
January 2019
3 Reads

Comparative study on serum-induced arthritis in the temporomandibular and limb joint of mice.

Int J Rheum Dis 2019 Jan 21. Epub 2019 Jan 21.

Department of Orthodontics, University Hospital of Bonn, Bonn, Germany.

Introduction: The subject of the present study was a systematic comparative analysis of the rheumatoid arthritis (RA)-induced pathomechanisms in the temporomandibular joint with those of the limb joints using the serum-induced arthritis K/BxN model.

Methods: In 18 BALB/c mice the induction of RA was performed according to the Kouskoff method. Another healthy cohort served as controls (n = 12). Read More

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http://doi.wiley.com/10.1111/1756-185X.13486
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http://dx.doi.org/10.1111/1756-185X.13486DOI Listing
January 2019
5 Reads

Early supplemental α2-macroglobulin attenuates cartilage and bone damage by inhibiting inflammation in collagen II-induced arthritis model.

Int J Rheum Dis 2019 Jan 4. Epub 2019 Jan 4.

The Second Hospital of Shanxi Medical University, Taiyuan, China.

Objective: To determine if early supplemental intra-articular α2-macroglobulin (A2M) has a chondroprotective effect in a collagen II-induced arthritis (CIA) mice model.

Methods: DBA/1 mice were randomized into four groups (n = 15/group): (a) CIA + 1.2 μg of A2M; (b) CIA + 0. Read More

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http://dx.doi.org/10.1111/1756-185X.13457DOI Listing
January 2019

Changes in the pattern of cytokine production from peripheral blood mononuclear cells in patients with rheumatoid arthritis treated with infliximab and their relation to plasma arginase activity.

Int J Rheum Dis 2018 Nov 12;21(11):1907-1914. Epub 2016 May 12.

Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan.

Aim: The aim of this study was to quantify the production of T-cell cytokines from the peripheral blood mononuclear cells (PBMCs) of RA patients before and after treatment with anti-tumor necrosis factor (TNF)-α infliximab (IFX).

Method: We stimulated the PBMCs of RA patients (n = 24) in vitro and quantified the cytokines in the culture supernatant using enzyme-linked immunosorbent assay.

Results: Unexpectedly, the cytokines tested, interferon (IFN)-γ, interleukin (IL)-4 and IL-17, were all found to have increased, rather than decreased, after the treatment. Read More

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http://dx.doi.org/10.1111/1756-185X.12864DOI Listing
November 2018
1 Read

Serum levels of Krebs von den Lungen-6 as a promising marker for predicting occurrence and deterioration of systemic sclerosis-associated interstitial lung disease from a Chinese cohort.

Int J Rheum Dis 2019 Jan 28;22(1):108-115. Epub 2018 Dec 28.

Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Graduate School of Peking Union Medical College, Beijing, China.

Aim: A prospective and longitudinal study to investigate the correlations between Krebs von den Lungen-6 (KL-6) serum levels and systemic sclerosis associated with interstitial lung disease (SSc-ILD).

Method: Blood samples of baseline and the time point at 2 years follow-up intervals were collected for the measurement of serum KL-6 levels. The baseline clinical, laboratory characteristics, and incidence density of newly diagnosed ILD during the follow up were compared between SSc patients with elevated serum KL-6 levels (KL-6 > 500 U/mL) and those with normal KL-6 levels (KL-6 ≤ 500 U/mL) at baseline. Read More

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http://dx.doi.org/10.1111/1756-185X.13452DOI Listing
January 2019
1 Read
1.771 Impact Factor

Ten-year observation of patients with primary Sjögren's syndrome: Initial presenting characteristics and the associated outcomes.

Int J Rheum Dis 2018 Dec 26. Epub 2018 Dec 26.

Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

Aim/introduction: Primary Sjögren's syndrome (pSS) is a prototypical systemic autoimmune disease that manifests with various signs and symptoms. Although some studies have examined these manifestations over the long-term course of the disease, the association between initial clinical and immunological factors and subsequent long-term manifestations has not been fully elucidated. The aim of this study is to identify initial clinical and immunological factors associated with subsequent manifestations in patients with pSS. Read More

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http://dx.doi.org/10.1111/1756-185X.13464DOI Listing
December 2018
1 Read

Evaluation of monosodium iodoacetate dosage to induce knee osteoarthritis: Relation with oxidative stress and pain.

Int J Rheum Dis 2018 Dec 25. Epub 2018 Dec 25.

Postgraduate Program in Biochemistry, Universidade Federal do Pampa (Unipampa), Uruguaiana, Brazil.

Aim: To determine the dose of monosodium iodoacetate (MIA) required to induce oxidative stress, as well as pain and edema; to confirm the induction of knee osteoarthritis (OA) symptoms in rats by the presence of reactive oxygen species (ROS) and reduction of antioxidant agents; and to verify the presence of histopathological injury in these affected joints.

Method: Biological markers of oxidative stress, pain, knee edema, and cartilage degeneration provided by different doses of MIA (0.5; 1. Read More

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http://dx.doi.org/10.1111/1756-185X.13450DOI Listing
December 2018

Endothelial cell injury is involved in atherosclerosis and lupus symptoms in gld.apoE mice.

Int J Rheum Dis 2018 Dec 21. Epub 2018 Dec 21.

Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.

Aim: Cardiovascular complications related to atherosclerosis are major causes of morbidity and mortality in patients with systemic lupus erythematosus (SLE). However, the underlying mechanisms are not fully understood. Endothelial dysfunction has been identified as having involvement in pathogenesis of cardiovascular diseases and SLE. Read More

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http://dx.doi.org/10.1111/1756-185X.13458DOI Listing
December 2018

Polyneuropathy associated with chronic hemodialysis: Clinical and electrophysiological study.

Int J Rheum Dis 2018 Dec 21. Epub 2018 Dec 21.

Neurology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Aim: To estimate the frequency and pattern of peripheral polyneuropathy (PNP) that may affect patients maintained on hemodialysis.

Patients And Methods: The study was carried out on 60 middle-aged male patients attending the Internal Medicine Department for maintenance hemodialysis. All were subjected to a complete neurological examination. Read More

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http://dx.doi.org/10.1111/1756-185X.13462DOI Listing
December 2018

Diagnostic accuracy of positron emission tomography for assessment of disease activity in large vessel vasculitis.

Int J Rheum Dis 2018 Nov 22. Epub 2018 Nov 22.

Division of Vascular Medicine, University Hospital, Ludwig-Maximilians-University, Munich, Germany.

Aim: To determine the diagnostic yield of F-fluorodeoxyglucose positron emission tomography (PET) in disease activity assessment of large vessel vasculitides (LVV).

Methods: Patients with LVV who had undergone PET (between 2004 and June 2010) or PET co-registered with computed tomography (PET/CT; since June 2010) were identified. Clinical disease activity was assessed using established scoring systems. Read More

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http://doi.wiley.com/10.1111/1756-185X.13440
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http://dx.doi.org/10.1111/1756-185X.13440DOI Listing
November 2018
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Association between cumulative methotrexate dose, non-invasive scoring system and hepatic fibrosis detected by Fibroscan in rheumatoid arthritis patients receiving methotrexate.

Int J Rheum Dis 2019 Feb 22;22(2):214-221. Epub 2018 Nov 22.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Thammasat University, Patumthani, Thailand.

Background: Methotrexate (MTX) is recommended by recent American College of Rheumatology and European League against Rheumatism guidelines as a first-line drug for rheumatoid arthritis (RA). Liver fibrosis, which occurs as a long-term side effect is of major concern. Monitoring aminotransferase and albumin is suggested in the guidelines, unfortunately this method is unreliable for detecting liver fibrosis. Read More

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http://dx.doi.org/10.1111/1756-185X.13442DOI Listing
February 2019

Assessment of the validity and reliability of the Jenkins Sleep Scale in ankylosing spondylitis.

Int J Rheum Dis 2019 Feb 22;22(2):275-279. Epub 2018 Nov 22.

PMR Department, School of Medicine, Marmara University, Istanbul, Turkey.

Aim: Ankylosing spondylitis (AS) affects sleep quality. Jenkins Sleep Scale (JSS) Evaluation Questionnaire is a simple and easy to understand scale. The aim of this study is to constitute validity and reliability of JSS-TR in AS patients. Read More

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http://dx.doi.org/10.1111/1756-185X.13447DOI Listing
February 2019
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Associations between Health Assessment Questionnaire Disability Index and physical performance in rheumatoid arthritis and osteoarthritis.

Int J Rheum Dis 2018 Dec 17. Epub 2018 Dec 17.

Department of Medicine, University of Otago, Dunedin, New Zealand.

Objectives: To investigate whether the Health Assessment Questionnaire Disability Index (HAQ-DI) reflects objective measures of physical function in people with osteoarthritis (OA) and rheumatoid arthritis (RA).

Methods: In total, 139 people, 71 with RA fulfilling the American College of Rheumatology (ACR) criteria (1987) and 68 with OA fulfilling ACR criteria for OA of the hip or knee, completed the HAQ-DI. Physical function was assessed using Timed Up and Go (TUG), 30 seconds Sit to Stand (STS), grip strength dynamometry and pedometer steps over 7 days. Read More

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http://dx.doi.org/10.1111/1756-185X.13460DOI Listing
December 2018

Allergy inhibitory receptor-1 inhibits autoantibody production via upregulation of apoptotic debris clearance by macrophages.

Int J Rheum Dis 2018 Dec 16;21(12):2071-2078. Epub 2018 Dec 16.

Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

Aim: Allergy inhibitory receptor-1 (Allergin-1) is a newly identified immune regulatory molecule thought to influence autoantibody production. Autoantibody production, like that observed in Allergin-1-deficient mice, is crucial in the pathogenesis of several autoimmune diseases such as systemic lupus erythematosus. The purpose of this study is to clarify the regulatory role of Allergin-1-mediated autoantibody production using a murine model of thymocytic anaphylaxis. Read More

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http://dx.doi.org/10.1111/1756-185X.13381DOI Listing
December 2018
1 Read