495,892 results match your criteria International Journal of Ozone Therapy[Journal]


[Antibiotic treatment of infections in burn patients - a systematic review].

Handchir Mikrochir Plast Chir 2019 Feb 14. Epub 2019 Feb 14.

Klinik für Plastische Chirurgie und Schwerbrandverletzte, Handchirurgiezentrum, Operatives Referenzzentrum für Gliedmaßentumore, BG Universitätskliniken Bergmannsheil.

Background: Due to the loss of the natural skin barrier function with reduced immune competence as a result of a plasma loss and the numerous intensive care interventions, burn patients are particularly at risk for infection.

Study Design: systematic review METHODS: A systematic review of German and English literature between 1990 and 2018 analyzes the epidemiological and diagnostic aspects as well as the therapeutic use of antibiotics in infections of burn patients in clinical trials.

Results: A total number of 53 randomized controlled clinical trials met the inclusion criteria. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0802-8882
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http://dx.doi.org/10.1055/a-0802-8882DOI Listing
February 2019
1 Read

The Heimann-Bielschowsky Phenomenon: A Retrospective Case Series and Literature Review.

Klin Monbl Augenheilkd 2019 Feb 14. Epub 2019 Feb 14.

Ophthalmology, Jules Gonin Eye Hospital, Lausanne, Switzerland.

Background: The Heimann-Bielschowsky phenomenon (HBP) is an unusual form of monocular vertical pendular nystagmus and is usually asymptomatic. It always occurs in an eye with longstanding, profound visual loss. Reports of HBP are few and HBP is probably underdiagnosed. Read More

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http://dx.doi.org/10.1055/a-0829-6001DOI Listing
February 2019

Influence of liquid-to-biogas ratio and alkalinity on the biogas upgrading performance in a demo scale algal-bacterial photobioreactor.

Bioresour Technol 2019 Feb 6;280:112-117. Epub 2019 Feb 6.

Department of Chemical Engineering and Environmental Technology, School of Industrial Engineering, University of Valladolid, Dr. Mergelina, s/n, 47011 Valladolid, Spain; Institute of Sustainable Processes, University of Valladolid, Dr. Mergelina, s/n, 47011 Valladolid, Spain. Electronic address:

The influence of the liquid-to-biogas ratio (L/G) and alkalinity on methane quality was evaluated in a 11.7 m outdoors horizontal semi-closed tubular photobioreactor interconnected to a 45-L absorption column (AC). CO concentrations in the upgraded methane ranged from <0. Read More

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http://dx.doi.org/10.1016/j.biortech.2019.02.029DOI Listing
February 2019

Characterization of microplastics in the surface waters of Kingston Harbour.

Sci Total Environ 2019 Feb 5;664:753-760. Epub 2019 Feb 5.

Centre for Marine Sciences, 1 Anguilla Close, University of the West Indies, Mona, Jamaica. Electronic address:

Microplastic contamination of the marine environment has garnered global attention in recent years, and its distribution and effects in many small island developing states (SIDS) are still undetermined. As such, this study serves to detail an investigation of the abundance, spatial distribution and characteristics of surface water microplastics in the Kingston Harbour, a heavily polluted embayment in Jamaica. Fortnightly sampling with a manta trawl (335 μm mesh) revealed non-variable concentrations of 0-5. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.01.319DOI Listing
February 2019

Photochemical degradation of BPF, BPS and BPZ in aqueous solution: Identification of transformation products and degradation kinetics.

Sci Total Environ 2019 Feb 5;664:595-604. Epub 2019 Feb 5.

Jožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia; International Postgraduate School Jožef Stefan, Jamova cesta 39, 1000 Ljubljana, Slovenia. Electronic address:

Bisphenols (BPs) are industrial chemicals that are used as monomers in the production of polycarbonate plastics and epoxy resins. These compounds can leach into the aqueous environment, where they can potentially have toxic effects. The aim of this study was to assess the photochemical degradation of three common bisphenols: BPF, BPS and BPZ in aqueous solution and determine their degradation kinetics and characterise their transformation products. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.02.064DOI Listing
February 2019

Duration of untreated illness and response to SRI treatment in Obsessive-Compulsive Disorder.

Eur Psychiatry 2019 Feb 11;58:19-26. Epub 2019 Feb 11.

Rita Levi Montalcini Department of Neuroscience, University of Turin, Italy and San Luigi Gonzaga University Hospital, Regione Gonzole 10, 10043, Orbassano, Torino, Italy.

Background: The duration of untreated illness (DUI) is a potentially modifiable parameter associated with worst prognosis in several psychiatric disorders, but poorly investigated in Obsessive-Compulsive Disorder (OCD). Our aims were to estimate the mean DUI in a large sample of individuals with OCD and its impact on response to the first ever adequate SRI treatment.

Methods: We retrospectively examined records of 251 patients with OCD (SCID-I, DSM-IV) who referred to our Department and were prospectively and naturalistically treated according to International Guidelines. Read More

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http://dx.doi.org/10.1016/j.eurpsy.2019.01.017DOI Listing
February 2019

Dynamics of intervention adoption, implementation, and maintenance inside organizations: The case of an obesity prevention initiative.

Soc Sci Med 2018 Dec 23;224:67-76. Epub 2018 Dec 23.

Department of Nutrition, Gillings School of Global Public Health, UNC Center for Health Promotion and Disease Prevention (a CDC Prevention Research Center), University of North Carolina at Chapel Hill, NC, USA. Electronic address:

Overall impact of public health prevention interventions relies not only on the average efficacy of an intervention, but also on the successful adoption, implementation, and maintenance (AIM) of that intervention. In this study, we aim to understand the dynamics that regulate AIM of organizational level intervention programs. We focus on two well-documented obesity prevention interventions, implemented in food carry-outs and stores in low-income urban areas of Baltimore, Maryland, which aimed to improve dietary behaviour for adults by providing access to healthier foods and point-of-purchase promotions. Read More

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http://dx.doi.org/10.1016/j.socscimed.2018.12.021DOI Listing
December 2018

Quality of Life Related to Oral Health and its Impact in Adults.

J Stomatol Oral Maxillofac Surg 2019 Feb 11. Epub 2019 Feb 11.

MD DDS, PhD. Doctor, Specialist in Stomatology. Professor of Oral Pathology, Faculty of Medicine and Health Sciences (School of Dentistry), Oral Health and Masticatory System Group (Bellvitge Biomedical Research Institute), IDIBELL, University of Barcelona, Departament of OdontoestomatologySecond Floor, Room 2.32, Faculty of Medicine and Health Sciences - School of Dentistry Campus Bellvitge, University of Barcelona, Spain.

Oral health is part of general health, and is recognized as an essential component of quality of life (QoL). For years, oral health was determined solely by the clinic, which did not allow an evaluation of the true impact of oral diseases on the patients' daily lives. The development of instruments for assessing QoL related to oral health has occurred due to the urgency of determining the effects of changes in the oral cavity of individuals. Read More

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http://dx.doi.org/10.1016/j.jormas.2019.02.004DOI Listing
February 2019

A six-month systems toxicology inhalation/cessation study in ApoE mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes.

Food Chem Toxicol 2019 Feb 11. Epub 2019 Feb 11.

PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000, Neuchâtel, Switzerland. Electronic address:

Smoking is one of the major modifiable risk factors in the development and progression of chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD). Modified-risk tobacco products (MRTP) are being developed to provide substitute products for smokers who are unable or unwilling to quit, to lessen the smoking-related health risks. In this study, the ApoE mouse model was used to investigate the impact of cigarette smoke (CS) from the reference cigarette 3R4F, or aerosol from two potential MRTPs based on the heat-not-burn principle, carbon-heated tobacco product 1. Read More

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http://dx.doi.org/10.1016/j.fct.2019.02.008DOI Listing
February 2019

The optimal use of imaging in Radiation Therapy for lymphoma - Guidelines from the International Lymphoma Radiation Oncology Group (ILROG).

Int J Radiat Oncol Biol Phys 2019 Feb 11. Epub 2019 Feb 11.

Department of Oncology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Radiation therapy (RT) for the management of lymphomas has evolved over the past decades. Large extended or involved fields have been replaced by smaller involved site or nodal volumes. Currently, customized plans are created for each individual patient that encompass only the areas involved by disease. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2019.02.001DOI Listing
February 2019

High-resolution characterization of allelic and haplotypic HLA frequency distribution in a Spanish population using high-throughput next-generation sequencing.

Hum Immunol 2019 Feb 11. Epub 2019 Feb 11.

Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.

Next-generation sequencing (NGS) at the HLA-A, -B, -C, -DPA1, -DPB1, -DQA1, -DQB1, -DRB1 and -DRB3/4/5 loci was performed on 282 healthy unrelated individuals from different major regions of Spain. High-resolution HLA genotypes defined by full sequencing of class I loci and extended coverage of class II loci were obtained to determine allele frequencies and also to estimate extended haplotype frequencies. HLA alleles were typed at the highest resolution level (4-field level, 4FL); with exception of a minor deviation in HLA-DPA1, no statistically significant deviations from expected Hardy Weinberg Equilibrium (HWE) proportions were observed for all other HLA loci. Read More

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http://dx.doi.org/10.1016/j.humimm.2019.02.005DOI Listing
February 2019

[Development of a modern methodological base for monitoring the content of vitamins in food and food supplements].

Vopr Pitan 2018 13;87(6):106-116. Epub 2018 Nov 13.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow.

The determination of vitamins in various food matrices is necessary for monitoring the quality and safety indicators of food, including the control of the use of vitamins as food additives - food colorings and antioxidants. As well it is necessary to evaluate the level of consumption of vitamins by different age and sex categories of the population. The analysis of the regulatory and methodical basis in the field of determining the content of vitamins in food, including food supplements, has been held. Read More

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http://dx.doi.org/10.24411/0042-8833-2018-10072DOI Listing
November 2018

[Specialized food products with modified carbohydrate profile for dietary correction of diet of patients with type 2 diabetes].

Vopr Pitan 2018 13;87(6):76-88. Epub 2018 Nov 13.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow.

In recent years, the incidence of diabetes mellitus (DM) in the world is growing steadily. According to the international diabetes Federation (IDF), the number of DM patients in the world in 2015 was 415 million, of them more than 90% - patients with type 2 diabetes. According to forecasts, in 2040 their number will increase to 642 million. Read More

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http://dx.doi.org/10.24411/0042-8833-2018-10069DOI Listing
November 2018

Female low dose tip syringes-increased complexity of use may compromise dosing accuracy in paediatric patients.

J Clin Pharm Ther 2019 Feb 14. Epub 2019 Feb 14.

Department of Pharmacy, UF Health Shands Children's Hospital, Newberry, Florida.

What Is Known And Objective: The International Organization for Standardization (ISO) created enteral device specifications to reduce tubing misconnections. The Global Enteral Device Supplier Association (GEDSA) supports a female design: standard and low dose tip (LDT). Concerns include increased complexity of use with adapters, dosing accuracy and workflow. Read More

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http://dx.doi.org/10.1111/jcpt.12810DOI Listing
February 2019

A CGE Framework for Modeling the Economics of Flooding and Recovery in a Major Urban Area.

Risk Anal 2019 Feb 14. Epub 2019 Feb 14.

Department of Economics, University of Western Ontario, London, ON, Canada.

Coastal cities around the world have experienced large costs from major flooding events in recent years. Climate change is predicted to bring an increased likelihood of flooding due to sea level rise and more frequent severe storms. In order to plan future development and adaptation, cities must know the magnitude of losses associated with these events, and how they can be reduced. Read More

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http://dx.doi.org/10.1111/risa.13285DOI Listing
February 2019

Association between birth attendant type and delivery site and perinatal outcomes.

Int J Gynaecol Obstet 2019 Feb 14. Epub 2019 Feb 14.

University of Alabama at Birmingham, Birmingham, Alabama.

Objective: To test the hypothesis that modified perinatal mortality, early neonatal mortality, and other measures of perinatal mortality are lower with facility births than with home births among deliveries conducted by traditional birth attendants (TBAs) or nurse-midwives.

Method: This population-based observational study used data collected prospectively for home and facility deliveries conducted by TBAs and nurse-midwives in 13 rural communities in Zambia between September 1, 2009, and December 31, 2015.

Results: We enrolled 48,956 pregnant women. Read More

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http://dx.doi.org/10.1002/ijgo.12786DOI Listing
February 2019

Next-Generation Sequencing of Infectious Pathogens.

JAMA 2019 Feb 14. Epub 2019 Feb 14.

Office of Advanced Molecular Detection, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.

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http://dx.doi.org/10.1001/jama.2018.21669DOI Listing
February 2019

Effect of transcranial direct current stimulation on the number of smoked cigarettes in tobacco smokers.

PLoS One 2019 14;14(2):e0212312. Epub 2019 Feb 14.

Neuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia.

Background: Recent studies reported that transcranial direct current stimulation (tDCS) applied over the dorsolateral prefrontal cortex (DLPFC) reduced craving and cigarette smoking. We aimed to evaluate whether 3 sessions of tDCS over the DLPFC modulate cigarette smoking which is a critical factor in tobacco smokers.

Methods: In a double-blinded, sham-controlled, parallel experimental study, 22 participants who wished to quit smoking received tDCS with the cathodal over the right DLPFC and anodal over the left DLPFC based on the 10-20 EEG international system (F4, F3) at an intensity of 1. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212312PLOS
February 2019

Immigrant Vietnamese women's adaptation to culture and society in rural areas of Korea.

PLoS One 2019 14;14(2):e0212265. Epub 2019 Feb 14.

College of Nursing, Chonnam National University, Gwangju, Korea.

Background: International marriages between Vietnamese women and Korean men have increased rapidly in Korea. Successful adaptation of these women is challenging, and concerns on the issue have been raised. Most existing studies have surveyed Vietnamese immigrant women in urban Korea; less is known about women residing in rural areas of Korea. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212265PLOS
February 2019

Molecular fungal community and its decomposition activity in sapwood and heartwood of 13 temperate European tree species.

PLoS One 2019 14;14(2):e0212120. Epub 2019 Feb 14.

Technische Universität Dresden, International Institute Zittau, Department of Bio- and Environmental Sciences, Zittau, Germany.

Deadwood is an important structural component in forest ecosystems and plays a significant role in global carbon and nutrient cycling. Relatively little is known about the formation and decomposition of CWD by microbial communities in situ and about the factors controlling the associated processes. In this study, we intensively analyzed the molecular fungal community composition and species richness in relation to extracellular enzyme activity and differences in decomposing sapwood and heartwood of 13 temperate tree species (four coniferous and nine deciduous species, log diameter 30-40 cm and 4 m long) in an artificial experiment involving placing the logs on the forest soil for six years. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212120PLOS
February 2019

Elucidating fitness components of the invasive dermestid beetle Trogoderma granarium combining deterministic and stochastic demography.

PLoS One 2019 14;14(2):e0212182. Epub 2019 Feb 14.

Department of Statistics, Athens University of Economics and Business, Athens, Greece.

The invasive dermestid khapra beetle, Trogoderma granarium, is an important pest of stored products that is subject to strict phytosanitary measures. In this study, we conducted a demographic analysis of this species at 30, 35 and 40°C, combining deterministic and stochastic approaches. The net reproductive rate, the intrinsic rate of increase, the finite rate of increase and the doubling time did not differ significantly between 30 and 35°C, while at 40°C we detected negative values of the intrinsic rate of increase and the doubling time. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212182PLOS
February 2019

A comparison of the Muenster, SIOP Boston, Brock, Chang and CTCAEv4.03 ototoxicity grading scales applied to 3,799 audiograms of childhood cancer patients treated with platinum-based chemotherapy.

PLoS One 2019 14;14(2):e0210646. Epub 2019 Feb 14.

BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.

Childhood cancer patients treated with platinums often develop hearing loss and the degree is classified according to different scales globally. Our objective was to compare concordance between five well-known ototoxicity scales used for childhood cancer patients. Audiometric test results (n = 654) were evaluated longitudinally and graded according Brock, Chang, International Society of Pediatric Oncology (SIOP) Boston, Muenster scales and the U. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210646PLOS
February 2019

Effects of angiotensin converting enzyme gene polymorphism on hypertension in Africa: A meta-analysis and systematic review.

PLoS One 2019 14;14(2):e0211054. Epub 2019 Feb 14.

School of Pharmacy, College of Health and Medical Sciences, Haramaya Univeristy, Harar, Ethiopia.

Background: Hypertension is dramatically increasing in Africa with evidence of increased severity and resistance to treatment. Although angiotensin converting enzyme gene polymorphism is associated with higher prevalence of hypertension, the evidence is inconclusive on its influence on the emerging pattern in Africa. This meta-analysis is conducted to pool the available evidence to inform future research and interventions. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211054PLOS
February 2019

A prescription support-tool for chronic management of oral antithrombotic combinations in adults based on a systematic review of international guidelines.

PLoS One 2019 14;14(2):e0211695. Epub 2019 Feb 14.

Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, AP-HP, Hôpital Pitié-Salpêtrière, Département Biostatistique Santé Publique et Information Médicale, Unité de Recherche Clinique PSL-CFX, Centre de Pharmacoépidémiologie (Cephepi), Paris, France.

Background: Oral antithrombotic (AT) drugs, which include antiplatelet and anticoagulant therapies, are widely implicated in serious preventable bleeding events. Avoiding inappropriate oral AT combinations is a major concern. Numerous practical guidelines have been released; a document to enhance prescriptions of oral AT combinations for adults would be of great help. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211695PLOS
February 2019

Recommendations of the Advisory Committee on Immunization Practices for Use of Hepatitis A Vaccine for Persons Experiencing Homelessness.

MMWR Morb Mortal Wkly Rep 2019 Feb 15;68(6):153-156. Epub 2019 Feb 15.

Hepatitis A (HepA) vaccination is recommended routinely for children at age 12-23 months, for persons who are at increased risk for hepatitis A virus (HAV) infection, and for any person wishing to obtain immunity. Persons at increased risk for HAV infection include international travelers to areas with high or intermediate hepatitis A endemicity, men who have sex with men, users of injection and noninjection drugs, persons with chronic liver disease, person with clotting factor disorders, persons who work with HAV-infected primates or with HAV in a research laboratory setting, and persons who anticipate close contact with an international adoptee from a country of high or interme-diate endemicity (1-3). Persons experiencing homelessness are also at higher risk for HAV infection and severe infection-associated outcomes. Read More

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http://www.cdc.gov/mmwr/volumes/68/wr/mm6806a6.htm?s_cid=mm6
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http://dx.doi.org/10.15585/mmwr.mm6806a6DOI Listing
February 2019
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Determinants and Variations of Hospital Costs in Patients With Lumbar Radiculopathy Hospitalized for Spinal Surgery.

Spine (Phila Pa 1976) 2019 Mar;44(5):355-362

I-CHER, Interuniversity Center for Health Economics Research Group, Belgium.

Study Design: A retrospective study.

Objective: The aim of this study was to determine hospital costs related to surgery for lumbar radiculopathy and identify determinants of intramural costs based on minimal hospital and claims data.

Summary Of Background Data: Costs related to the initial hospitalization of patients undergoing surgery for lumbar radiculopathy make up the major part of direct health care expenditure in this population. Read More

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http://dx.doi.org/10.1097/BRS.0000000000002801DOI Listing

Indications for echocardiography of replacement heart valves: a joint statement from the BHVS and BSE.

Echo Res Pract 2019 Feb 1. Epub 2019 Feb 1.

R Steeds, Cardiology, University Hospital of Birmingham, Birmingham, United Kingdom of Great Britain and Northern Ireland.

Echocardiography plays a vital role in the follow up of patients with replacement heart valves. However, there is considerable variation in international guidelines regarding the recommended time points after implantation at which routine echocardiography should be performed. The purpose of routine echocardiography is to detect early structural valve deterioration in biological valves to improve the timing of redo interventions. Read More

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http://dx.doi.org/10.1530/ERP-18-0079DOI Listing
February 2019

Complex diseases and co-morbidities: polycystic ovary syndrome and type 2 diabetes mellitus.

Endocr Connect 2019 Feb 1. Epub 2019 Feb 1.

H Teede, Monash Centre for Health Research and Implementation, Monash University, Clayton, Australia.

Objective: Many complex diseases exhibit co-morbidities often requiring management by more than one health specialist. We examined cross-speciality issues that ultimately affect the health and wellbeing of patients with polycystic ovary syndrome (PCOS). PCOS was originally described as a reproductive condition but is now recognised to also be a metabolic and psychological condition affecting 8-13% of women of reproductive age. Read More

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https://ec.bioscientifica.com/view/journals/ec/aop/ec-18-050
Publisher Site
http://dx.doi.org/10.1530/EC-18-0502DOI Listing
February 2019
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Accuracy assessment of consecutive test strip lots for whole blood INR point-of-care instruments: clarifying the role of frozen plasma pools.

Clin Chem Lab Med 2019 Feb 14. Epub 2019 Feb 14.

Coagulation Reference Laboratory, Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, The Netherlands.

Background In the Netherlands, each new lot of test strips for the CoaguChek XS is validated by a group of collaborating centers. The purpose of this study was to assess the accuracy of the international normalized ratio (INR) measured with consecutive test strip lots and the suitability of frozen plasma pools for accuracy evaluation. Methods Each year, a particular lot of CoaguChek XS test strips is used as reference lot. Read More

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http://dx.doi.org/10.1515/cclm-2018-1054DOI Listing
February 2019

Google Trends predicts present and future plague cases during the plague outbreak in Madagascar: insights and implications from an infodemiological study.

JMIR Public Health Surveill 2019 Jan 18. Epub 2019 Jan 18.

Tel Aviv University, Tel Aviv, IL.

Background: Plague is a highly infectious zoonotic disease caused by the bacillus Yersinia pestis. Three major forms of the disease are known: bubonic, septicemic, and pneumonic plague. Though being strictly related to past history, plague still represents a global public health concern. Read More

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http://dx.doi.org/10.2196/13142DOI Listing
January 2019

Building State and Local Public Health Capacity in Syndromic Surveillance Through an Online Community of Practice.

Public Health Rep 2019 Feb 14:33354919828713. Epub 2019 Feb 14.

3 Arizona Department of Health Services, Phoenix, AZ, USA.

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http://dx.doi.org/10.1177/0033354919828713DOI Listing
February 2019

Brazil's Fight against Hepatitis C - Universalism, Local Production, and Patents.

N Engl J Med 2019 Feb;380(7):605-607

From the Department of Public Administration, São Paulo Business School, São Paulo (E.M.F.), and the Oswaldo Cruz Foundation, Rio de Janeiro (F.I.B.) - both in Brazil; the Center for Latin American Studies, University of California, Berkeley, Berkeley (E.M.F.); and the Department of International Development, London School of Economics and Political Science, London (K.S.). Data collection for this article was funded under the auspices of the São Paulo Research Foundation.

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http://dx.doi.org/10.1056/NEJMp1812959DOI Listing
February 2019

Universal Medicine Access through Lump-Sum Remuneration - Australia's Approach to Hepatitis C.

N Engl J Med 2019 Feb;380(7):607-610

From the Graduate Institute of International and Development Studies, Geneva (S.M., E.E.); and the Harvard T.H. Chan School of Public Health, Boston (S.M.).

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http://dx.doi.org/10.1056/NEJMp1813728DOI Listing
February 2019

Performance of the adapted Diabetes Complications Severity Index translated to ICD-10.

Am J Manag Care 2019 Feb 1;25(2):e45-e49. Epub 2019 Feb 1.

Institute of General Practice, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Email:

Objectives: To assess the performance of the adapted Diabetes Complications Severity Index (aDCSI) translated to International Classification of Diseases, Tenth Revision (ICD-10) in predicting hospitalizations, mortality, and healthcare-associated costs.

Study Design: Retrospective closed cohort study based on secondary data analysis.

Methods: We translated the aDCSI to ICD-10 and calculated aDCSI scores based on health insurance claims data. Read More

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February 2019

Portal vein tumor thrombus from gastric cancer.

J Ultrason 2018 ;18(75):365-368

Pathology Department, Hospital Tuanku Ja'afar , Jalan Rasah, Negeri Sembilan , Malaysia.

A 53-year-old woman presented with left-sided abdominal pain, nausea and vomiting for the past 3 months with associated loss of appetite and weight. On physical examination, there was a large, ill-defined, firm mass at the epigastrium. Ultrasonography showed heterogeneously hypoechoic filling defect within the dilated main portal vein. Read More

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http://dx.doi.org/10.15557/JoU.2018.0054DOI Listing
January 2018

Serum TSH level in obese children and its correlations with atherogenic lipid indicators and carotid intima media thickness.

J Ultrason 2018 ;18(75):296-301

Department of Pediatrics and Endocrinology, Medical University of Warsaw , Poland.

Moderately elevated level of thyroid-stimulating hormone accompanied by normal serum concentrations of free thyroxine, suggesting subclinical hypothyroidism, is the most common hormonal abnormality in obese children. Controversy remains, whether a thyroid dysfunction related to obesity has an influence on the cardiovascular risk factors. The aim of the study was to assess correlation between thyroid-stimulating hormone and free thyroxine and chosen atherogenic lipid indicators, and carotid intima media thickness in obese children and adolescents. Read More

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http://dx.doi.org/10.15557/JoU.2018.0043DOI Listing
January 2018

Synthesis and Applications of Red-emissive Carbon Dots.

Chem Rec 2019 Feb 14. Epub 2019 Feb 14.

MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry & Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, China.

Carbon dots (CDs), a new class of fluorescent carbon nanoparticles (less than 10 nm in size), have been widely applied in various fields, including sensors, bioimaging, catalysis, light-emitting devices (LEDs), and photoelectronic devices, owing to their unique properties such as low toxicity, bio-compatibility, high photostability, easy surface modification, and up-conversion fluorescence, over the past decades. Recently, multiple-color-emissive CDs, especially red-emissive CDs (RCDs), have drawn much attention owing to their unique advantages, like the ability to penetrate the animal bodies without the disturbance of strong tissue autofluorescence, multiple-color fluorescence displaying or sensing, and the capacity to be one essential component to obtain white LED (WLED). In this review, we focused on the progress of recently-emerging RCDs in the past five years, including their synthetic methods (hydrothermal, solvothermal, reflux condensation and microwave techniques), influencing factors (precursors, solvents, elements doping, surface chemistry) and various applications (bioimaging, sensor, photocatalysis and WLEDs), with a perspective on the future advancements. Read More

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http://doi.wiley.com/10.1002/tcr.201800172
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http://dx.doi.org/10.1002/tcr.201800172DOI Listing
February 2019
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Perspectives on facilitating whole exome sequencing for international patients at Mayo Clinic.

J Genet Couns 2019 Feb 14. Epub 2019 Feb 14.

Department of Clinical Genomics, Mayo Clinic, Rochester, Minnesota.

Whole exome sequencing (WES) has become a fundamental component of genetic evaluation and diagnosing rare genetic diseases. This test is now offered to patients from a wide variety of cultural backgrounds and in various clinical and research settings. This commentary is a reflection of one group of clinical genetic counselors' experiences in facilitating WES for patients who come from outside the United States for genetic evaluation and pursue WES. Read More

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http://dx.doi.org/10.1002/jgc4.1100DOI Listing
February 2019

Research evidence on strategies enabling integration of electronic health records in the health care systems of low- and middle-income countries: A literature review.

Int J Health Plann Manage 2019 Feb 14. Epub 2019 Feb 14.

Carolina Health Informatics Program, University of North Carolina at Chapel Hill, North Carolina, USA.

Integration of electronic health records (EHRs) in the national health care systems of low- and middle-income countries (LMICs) is vital for achieving the United Nations Sustainable Development Goal of ensuring healthy lives and promoting well-being for all people of all ages. National EHR systems are increasing, but mostly in developed countries. Besides, there is limited research evidence on successful strategies for ensuring integration of national EHRs in the health care systems of LMICs. Read More

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http://dx.doi.org/10.1002/hpm.2754DOI Listing
February 2019

Patient costs of hypertension care in public health care facilities in Kenya.

Int J Health Plann Manage 2019 Feb 14. Epub 2019 Feb 14.

Health Economics Research Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.

Background: Hypertension in low- and middle-income countries, including Kenya, is of economic importance due to its increasing prevalence and its potential to present an economic burden to households. In this study, we examined the patient costs associated with obtaining care for hypertension in public health care facilities in Kenya.

Methods: We conducted a cross-sectional study among adult respondents above 18 years of age, with at least 6 months of treatment in two counties. Read More

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http://dx.doi.org/10.1002/hpm.2752DOI Listing
February 2019

Effects of therapeutic plasma exchange on anticoagulants in patients receiving therapeutic anticoagulation: a systematic review.

Transfusion 2019 Feb 14. Epub 2019 Feb 14.

Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina.

Therapeutic plasma exchange (TPE) removes coagulation proteins, but its impact on therapeutic anticoagulation is unknown. We performed a systematic review of the literature to determine the coagulation effects of TPE in patients receiving systemic anticoagulation. We searched MEDLINE, CINAHL, EMBASE, and Web of Science until June 2018 for studies combining controlled vocabulary and keywords related to therapeutic plasma exchange, plasmapheresis, anticoagulants, and therapy. Read More

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http://dx.doi.org/10.1111/trf.15191DOI Listing
February 2019

Assessment of the diagnostic value of using serum CA125 and GI-RADS system in the evaluation of adnexal masses.

Medicine (Baltimore) 2019 Feb;98(7):e14577

Department of Gynecology and Obstetrics, Key Laboratory of Obstetric and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital, Sichuan University, Chengdu.

Cancer antigen 125 (CA125) is a valuable tumor marker for ovarian cancer. Gynecology Imaging Reporting and Data System (GI-RADS) is proved to be effective at identifying the adnexal masses. We investigated whether the combination of these two methods can improve the diagnostic accuracy of ovarian cancer. Read More

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http://dx.doi.org/10.1097/MD.0000000000014577DOI Listing
February 2019
5.723 Impact Factor

Acupuncture for perimenopausal depressive disorder: A systematic review and meta-analysis protocol.

Medicine (Baltimore) 2019 Feb;98(7):e14574

Yunnan University of Chinese Medicine, Kunming, Yunnan.

Background: Perimenopausal depressive disorder (PDD) is a disease that plagues many perimenopausal women. There is an urgent need for a safe way to treat the disease. With few side effects, acupuncture treatment for PDD has been gradually accepted. Read More

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http://dx.doi.org/10.1097/MD.0000000000014574DOI Listing
February 2019

Randomized, open-label, multicenter study of azithromycin compared with doxycycline for treating anorectal Chlamydia trachomatis infection concomitant to a vaginal infection (CHLAZIDOXY study).

Medicine (Baltimore) 2019 Feb;98(7):e14572

University Bordeaux.

Background: Chlamydia trachomatis can lead to a persistent infection in the lower gastrointestinal tract, suggesting a potential role of autoinoculation of cervical chlamydial infection from the rectal site, contributing to repeat infections. Moreover, around 75% of women with urogenital C. trachomatis have concurrent anorectal infection. Read More

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http://dx.doi.org/10.1097/MD.0000000000014572DOI Listing
February 2019

Increased risk of neurodegenerative dementia in women with migraines: A nested case-control study using a national sample cohort.

Medicine (Baltimore) 2019 Feb;98(7):e14467

Department of Laboratory Medicine, Hallym University College of Medicine, Anyang, Korea.

The present study aimed to evaluate the association between migraines and dementia.Data were collected from 11,438 dementia participants who were 1:4 matched by age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia with 45,752 controls from the Korean National Health Insurance Service-National Sample Cohort from 2002 to 2013. Dementia was diagnosed using the International Classification of Disease-10 (ICD-10) codes (G30 or F00). Read More

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http://dx.doi.org/10.1097/MD.0000000000014467DOI Listing
February 2019

The triad of diabetes ketoacidosis, hypertriglyceridemia and acute pancreatitis. How does it affect mortality and morbidity?: A 10-year analysis of the National Inpatient Sample.

Medicine (Baltimore) 2019 Feb;98(7):e14378

Gastroenterology and Hepatology Department, Digestive Disease Institute.

The triad of acute pancreatitis (AP) coexisting with diabetes ketoacidosis (DKA) and hypertriglyceridemia (HTG) has been reported, but no impact on mortality has been found to date. We aim to assess if patients with this triad are at a higher inpatient mortality compared to patients with acute pancreatitis only.Retrospective cohort. Read More

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http://dx.doi.org/10.1097/MD.0000000000014378DOI Listing
February 2019

Neurophysiological Differences in Emotional Processing by Cochlear Implant Users, Extending Beyond the Realm of Speech.

Ear Hear 2019 Feb 11. Epub 2019 Feb 11.

Department of Otolaryngology-Head and Neck Surgery, McGill University, Montreal, Canada.

Objective: Cochlear implants (CIs) restore a sense of hearing in deaf individuals. However, they do not transmit the acoustic signal with sufficient fidelity, leading to difficulties in recognizing emotions in voice and in music. The study aimed to explore the neurophysiological bases of these limitations. Read More

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http://dx.doi.org/10.1097/AUD.0000000000000701DOI Listing
February 2019

Validation of noninvasive oscillometric blood pressure 2020 up pressure upper arm blood pressure monitoring technology according to the European Society of Hypertension International Protocol revision 2010.

Blood Press Monit 2019 Feb 11. Epub 2019 Feb 11.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department of Nephrology.

To validate noninvasive oscillometric blood pressure (NIBP) 2020 up pressure (UP) upper arm blood pressure (BP) monitoring technology according to the European Society of Hypertension International Protocol revision 2010 (ESH-IP revision 2010). According to the protocol, 33 participants were included. NIBP2020 UP technology was integrated into the BP+ host device, and common upper arm cuffs were used. Read More

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http://dx.doi.org/10.1097/MBP.0000000000000370DOI Listing
February 2019

Determining Best Practices for Management of Bacteriuria in Spinal Cord Injury: Protocol for a Mixed-Methods Study.

JMIR Res Protoc 2019 Feb 14;8(2):e12272. Epub 2019 Feb 14.

Center for Innovations in Quality, Effectiveness and Safety, Houston, TX, United States.

Background: Bacteriuria, either asymptomatic (ASB) or symptomatic, urinary tract infection (UTI), is common in persons with spinal cord injury (SCI). Current Veterans Health Administration (VHA) guidelines recommend a screening urinalysis and urine culture for every veteran with SCI during annual evaluation, even when asymptomatic, which is contrary to other national guidelines. Our preliminary data suggest that a positive urine culture (even without signs or symptoms of infection) drives antibiotic use. Read More

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https://www.researchprotocols.org/2019/2/e12272/
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http://dx.doi.org/10.2196/12272DOI Listing
February 2019
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Digital Education in Health Professions: The Need for Overarching Evidence Synthesis.

J Med Internet Res 2019 02 14;21(2):e12913. Epub 2019 Feb 14.

Health Workforce Department, World Health Organization, Geneva, Switzerland.

Synthesizing evidence from randomized controlled trials of digital health education poses some challenges. These include a lack of clear categorization of digital health education in the literature; constantly evolving concepts, pedagogies, or theories; and a multitude of methods, features, technologies, or delivery settings. The Digital Health Education Collaboration was established to evaluate the evidence on digital education in health professions; inform policymakers, educators, and students; and ultimately, change the way in which these professionals learn and are taught. Read More

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http://dx.doi.org/10.2196/12913DOI Listing
February 2019