4,468 results match your criteria International Journal of Colorectal Disease[Journal]


Prevalence of alpha-1-antitrypsin deficiency carriers in a population with and without colonic diverticula. A multicentre prospective case-control study: the ALADDIN study.

Int J Colorectal Dis 2019 Feb 15. Epub 2019 Feb 15.

Department of Surgery, Northwest Clinics, Wilhelminalaan 12, 1815 JD, Alkmaar/Den Helder, Netherlands.

Purpose: The underling pathophysiological mechanisms that cause the formation of colonic diverticula (diverticulosis) remain unclear. Connective tissue changes due to ageing that cause changes in collagen structure of the colonic wall is one theory. Alpha-1-antitrypsin (A1AT) is a protease inhibitor known to protect connective tissue in other organs. Read More

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http://dx.doi.org/10.1007/s00384-019-03248-8DOI Listing
February 2019

Correction to: Appendicitis as a manifestation of colon cancer: should we image the colon after appendicectomy in patients over the age of 40 years?

Int J Colorectal Dis 2019 Feb 15. Epub 2019 Feb 15.

Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK.

The above article originally published with an error present in Table 1 and is now presented correctly in this article. Read More

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http://dx.doi.org/10.1007/s00384-019-03262-wDOI Listing
February 2019

Appendicectomy in older patients with acute appendicitis is not an indication for routine colonoscopy.

Int J Colorectal Dis 2019 Feb 14. Epub 2019 Feb 14.

Department of Accident and Emergency, St Helens and Knowsley Hospitals NHS Trust, Prescot, UK.

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http://dx.doi.org/10.1007/s00384-019-03264-8DOI Listing
February 2019

Long distance to hospital is not a risk factor for non-reversal of a defunctioning stoma.

Int J Colorectal Dis 2019 Feb 12. Epub 2019 Feb 12.

Department of Surgical and Perioperative Sciences, Umeå University, SE-901 88, Umeå, Sweden.

Purpose: To see if road distance to hospital influences stoma reversal rate, time from index operation to stoma reversal, and occurrence of permanent stoma.

Methods: Data from all diagnosed cases of rectal cancer from three counties in northern Sweden were extracted from the Swedish Rectal Cancer Registry. The three counties are sparsely populated, with a population density roughly one fifth the average density in Sweden. Read More

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http://dx.doi.org/10.1007/s00384-019-03258-6DOI Listing
February 2019

Ileostomy versus fecal diversion device to protect anastomosis after rectal surgery: a randomized clinical trial.

Int J Colorectal Dis 2019 Feb 11. Epub 2019 Feb 11.

Department of Surgery, College of Medicine, Yeungnam University, 170, Hyeonchung-ro, Nam-gu, Daegu, 42415, South Korea.

Purpose: Patients with rectal anastomosis commonly experience various ileostomy-related complications. This study aimed to elucidate the usefulness of a fecal diversion device (FDD) as an alternative to ileostomy for protecting rectal anastomosis.

Methods: Patients with rectal anastomosis were randomly assigned to the ileostomy and FDD groups except in cases of emergency surgery. Read More

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http://link.springer.com/10.1007/s00384-019-03255-9
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http://dx.doi.org/10.1007/s00384-019-03255-9DOI Listing
February 2019
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Clinical and endoscopic complications of Epstein-Barr virus in inflammatory bowel disease: an illustrative case series.

Int J Colorectal Dis 2019 Feb 9. Epub 2019 Feb 9.

Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

Background And Aim: Epstein-Barr virus (EBV) is a proposed trigger in the etiopathogenesis of inflammatory bowel disease (IBD) and is associated with lymphoproliferative diseases. Nevertheless, testing for EBV DNA in the intestinal mucosa and screening for EBV infection before initiation of a drug therapy are not routinely performed. The aim of this article is to increase awareness of the relevance of EBV infection in specific clinical situations. Read More

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http://dx.doi.org/10.1007/s00384-019-03257-7DOI Listing
February 2019

Prognostic significance of doubling time in patients undergoing radical surgery for metachronous peritoneal metastases of colorectal cancer.

Int J Colorectal Dis 2019 Feb 9. Epub 2019 Feb 9.

Department of Surgical Oncology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Purpose: The doubling times of tumor volume and tumor markers are associated with the prognosis of liver or lung metastases from colorectal cancer (CRC). However, no studies have assessed peritoneal metastases. Therefore, we aimed to elucidate the association between doubling time and the prognosis of patients who underwent radical surgery for metachronous peritoneal metastases of CRC. Read More

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http://dx.doi.org/10.1007/s00384-019-03259-5DOI Listing
February 2019
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Correction to: Short-term outcome of laparoscopic versus robotic ventral mesh rectopexy for full-thickness rectal prolapse. Is robotic superior?

Int J Colorectal Dis 2019 Feb 9. Epub 2019 Feb 9.

Department of Colorectal Surgery, Royal Liverpool and Broadgreen University Hospital NHS Trust, University of Liverpool, Liverpool, L7 8XP, UK.

The authors wish to clarify a number of points that were incorrectly stated in the original article. These changes do not invalidate the article. Read More

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http://dx.doi.org/10.1007/s00384-019-03247-9DOI Listing
February 2019

Refractory major LARS: stoma can wait.

Int J Colorectal Dis 2019 Feb 9. Epub 2019 Feb 9.

Department of General and Specialist Surgery, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1007/s00384-019-03261-xDOI Listing
February 2019
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To what extent is the low anterior resection syndrome (LARS) associated with quality of life as measured using the EORTC C30 and CR38 quality of life questionnaires?

Int J Colorectal Dis 2019 Feb 5. Epub 2019 Feb 5.

Department of General, Visceral and Thoracic Surgery, Dresden-Friedrichstadt General Hospital, Teaching Hospital of the Technical University of Dresden, Friedrichstr. 41, D-01067, Dresden, Germany.

Purpose: Treatment of rectal cancer often results in disturbed anorectal function, which can be quantified by the Low Anterior Resection Syndrome (LARS) score. This study investigates the association of impaired anorectal function as measured with the LARS score with quality of life (QoL) as measured with the EORTC-QLQ-C30 and CR38 questionnaires.

Methods: All stoma-free patients who had undergone sphincter-preserving surgery for rectal cancer from 2000 to 2014 in our institution were retrieved from a prospective database. Read More

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http://dx.doi.org/10.1007/s00384-019-03249-7DOI Listing
February 2019
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Endoscopic pilonidal sinus treatment (EPSiT) in recurrent pilonidal disease: a prospective international multicenter study.

Int J Colorectal Dis 2019 Feb 4. Epub 2019 Feb 4.

Department of Surgery, EOC Hospital, Mendrisio, Switzerland.

Background: Pilonidal disease (PD) is a common disease of the natal cleft, which can lead to complications including infection and abscess formation. Various operative management options are available, but the ideal technique is still debatable. Recurrent PD after surgical treatment is frequent event for the 25-30% of cases. Read More

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http://link.springer.com/10.1007/s00384-019-03256-8
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http://dx.doi.org/10.1007/s00384-019-03256-8DOI Listing
February 2019
2 Reads

Determination of the transection margin during colorectal resection with hyperspectral imaging (HSI).

Int J Colorectal Dis 2019 Feb 2. Epub 2019 Feb 2.

Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Liebigstr. 20, D-04103, Leipzig, Germany.

Purpose: This study evaluated the use of hyperspectral imaging for the determination of the resection margin during colorectal resections instead of clinical macroscopic assessment.

Methods: The used hyperspectral camera is able to record light spectra from 500 to 1000 nm and provides information about physiologic parameters of the recorded tissue area intraoperatively (e.g. Read More

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http://dx.doi.org/10.1007/s00384-019-03250-0DOI Listing
February 2019
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Three-dimensional high-resolution anorectal manometry in functional anorectal disorders: results from a large observational cohort study.

Int J Colorectal Dis 2019 Jan 31. Epub 2019 Jan 31.

Gastroenterology Department, North Hospital, Assistance Publique Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.

Background: The aim of the study was to describe the results of 3D high-resolution anorectal manometry (3DHRAM) in a large cohort of patients with functional anorectal disorders.

Methods: In this single-center retrospective study, all consecutive patients referred for investigation of fecal incontinence (FI) or dyssynergic defecation (DD) underwent 3DHRAM. The parameters analyzed were usual manometric data, repartition of dyssynergic patterns, and the prevalence of a new "muscular subtype classification" underlying dyssynergia, anal sphincter defects, and pelvic floor disorders. Read More

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http://dx.doi.org/10.1007/s00384-019-03235-zDOI Listing
January 2019
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Appendix orifice polyps: a study of 691 lesions at a single institution.

Int J Colorectal Dis 2019 Jan 30. Epub 2019 Jan 30.

Department of Colorectal Surgery, Digestive Diseases and Surgery Institute, Cleveland Clinic Foundation, Cleveland, OH, 44195, USA.

Purpose: Data on the management of appendix orifice lesions are limited. We present our experience on the management of appendix orifice lesions focusing on the range of size, histology, treatment, and outcomes for polyps at the appendix orifice.

Methods: Retrospective descriptive study at a tertiary referral center. Read More

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http://link.springer.com/10.1007/s00384-019-03251-z
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http://dx.doi.org/10.1007/s00384-019-03251-zDOI Listing
January 2019
5 Reads

Associations between multiple immunosuppressive treatments before surgery and surgical morbidity in patients with ulcerative colitis during the era of biologics.

Int J Colorectal Dis 2019 Jan 26. Epub 2019 Jan 26.

Division of Infection Control and Prevention, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.

Purpose: It is unclear whether immunomodulators or biologics, with the exception of corticosteroids, can be risk factors for postoperative infectious complications of ulcerative colitis (UC). Moreover, many immunosuppressive therapies including some biologics are used mainly to treat UC, and many patients are on multi-agent immunosuppressive therapy at the time of surgery. Therefore, we evaluated the influence of pre-operative multiple immunosuppressive agents on the occurrence of surgical site infection (SSI) in UC during the era of biologics. Read More

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http://dx.doi.org/10.1007/s00384-019-03253-xDOI Listing
January 2019
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Diverted versus undiverted restorative proctocolectomy for chronic ulcerative colitis: an analysis of long-term outcomes after pouch leak short title: outcomes after pouch leak.

Int J Colorectal Dis 2019 Jan 25. Epub 2019 Jan 25.

Department of Surgery, Icahn School of Medicine at Mount Sinai, 5 E 98th St., 15th Floor, New York, NY, 10029, USA.

Background: The safety of undiverted restorative proctocolectomy (RPC) is debated. This study compares long-term outcomes after pouch leak in diverted and undiverted RPC patients.

Methods: Data were obtained from a prospectively maintained registry from a single surgical practice. Read More

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http://dx.doi.org/10.1007/s00384-019-03240-2DOI Listing
January 2019

Impact of the preoperative prognostic nutritional index on postoperative and survival outcomes in colorectal cancer patients who underwent primary tumor resection: a systematic review and meta-analysis.

Int J Colorectal Dis 2019 Jan 24. Epub 2019 Jan 24.

Department of Anorectal Surgery, The First Hospital of China Medical University, Shenyang, 110001, People's Republic of China.

Purpose: We aimed to explore whether the preoperative prognostic nutritional index (PNI) could be an indicator of prognostic outcomes in colorectal cancer (CRC) patients.

Methods: A systematic review and meta-analysis was conducted using the PubMed, Embase, and Web of Science databases. All original comparative studies published in English that were related to a high PNI versus a low PNI in CRC patients were included. Read More

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http://dx.doi.org/10.1007/s00384-019-03241-1DOI Listing
January 2019

What's wrong with the status quo? Plenty.

Int J Colorectal Dis 2019 Jan 24. Epub 2019 Jan 24.

UCSF ANCRE Center, Mount Zion Hospital, San Fracisco, California, USA.

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http://dx.doi.org/10.1007/s00384-019-03246-wDOI Listing
January 2019

Predictors of toxicity-related hospitalization in four randomized studies of 5-fluorouracil-based chemotherapy in metastatic colorectal cancer.

Int J Colorectal Dis 2019 Jan 24. Epub 2019 Jan 24.

Department of Oncology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

Objective: To evaluate the predictors of toxicity-related hospitalization associated with various chemotherapy regimens among metastatic colorectal cancer patients METHODS: This pooled analysis includes patient-level datasets from four randomized clinical studies (NCT00272051; NCT00305188; NCT00115765; NCT00364013). Through univariate and multivariate logistic regression analyses, factors predicting the development of serious adverse events, fatal adverse events, and toxicity-related hospitalizations were determined.

Results: A total of 2533 patients were included in the current study. Read More

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http://dx.doi.org/10.1007/s00384-019-03252-yDOI Listing
January 2019

The relation between oncologic outcomes and metastatic lymph node location following laparoscopic resection of stage III colon cancer.

Int J Colorectal Dis 2019 Jan 23. Epub 2019 Jan 23.

Department of Surgery, Chonnam National University Hwasun Hospital, 322 Seoyang-ro, Hwasun-eup, Hwasun-gun, Jeonnam, 58128, Republic of Korea.

Purpose: Colon cancers are staged by assessing more than 12 lymph nodes, but there is still a controversy over the number of lymph nodes. Only a few studies of metastatic lymph node position in colon cancer have been published with its significance not completely understood. This study aimed to compare survival rates according to metastatic lymph node position following radical lymph node dissection for stage III colon cancers. Read More

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http://dx.doi.org/10.1007/s00384-019-03245-xDOI Listing
January 2019
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Carcinoembryonic antigen reduction after medical treatment in patients with metastatic colorectal cancer: a systematic review and meta-analysis.

Int J Colorectal Dis 2019 Jan 22. Epub 2019 Jan 22.

Department of Oncology, Ospedale Civile di Sanremo, Via G. Borea n. 56, I-18038, Sanremo (Imperia), Italy.

Purpose: The introduction of new drugs and multimodal treatments for the management of patients with metastatic colorectal cancer (mCRC) has reduced the importance of time-to-event endpoints and reported the attention on the response-related endpoints. Furthermore, the prognostic role of the surgical scores before the resection of metastases has not been confirmed for multimodal treatments. The purpose of this research is to perform a meta-analysis of the studies that evaluated the relationship between carcinoembryonic antigen (CEA) response and outcome in patients with mCRC receiving systemic chemotherapy. Read More

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http://dx.doi.org/10.1007/s00384-018-03230-wDOI Listing
January 2019
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Comparison of conservative versus surgical therapy for acute appendicitis with abscess in five German hospitals.

Int J Colorectal Dis 2019 Jan 22. Epub 2019 Jan 22.

Helios Klinikum Schleswig, Schleswig, Germany.

Introduction: The aim of this study was to evaluate the effectiveness of initially conservative therapy compared to immediate appendectomy for acute appendicitis with abscess in terms of medical and economic outcomes.

Methods: Of all the patients treated for appendicitis from January 2009 to December 2017 in five German hospitals, 240 were included in the study. Fifty-three patients received conservative (CON) and 195 patients received surgical (SUR) therapy as initial treatment. Read More

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http://link.springer.com/10.1007/s00384-019-03238-w
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http://dx.doi.org/10.1007/s00384-019-03238-wDOI Listing
January 2019
2 Reads

Preoperative T staging of colon cancer using CT colonography with multiplanar reconstruction: new diagnostic criteria based on "bordering vessels".

Int J Colorectal Dis 2019 Jan 21. Epub 2019 Jan 21.

Colorectal Surgery Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 1040045, Japan.

Purpose: Preoperative T staging of colon cancer, in particular, for distinguishing T3 from T2 and T4, has been a challenge. The aim of this study was to evaluate newly developed criteria for preoperative T staging of colorectal cancer using computed tomography colonography (CTC) with multiplanar reconstruction (MPR), based on the spatial relationship of tumors and "bordering vessels," that is, marginal vessels that are detectable by multi-detector row CT with MPR.

Methods: A total of 172 patients with colon and upper rectal cancer who underwent preoperative CTC and surgery between August 2011 and September 2013 were included. Read More

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http://dx.doi.org/10.1007/s00384-019-03236-yDOI Listing
January 2019

Appendiceal endometriosis invading the sigmoid colon: a rare entity.

Int J Colorectal Dis 2019 Jan 21. Epub 2019 Jan 21.

Department of Minimally Invasive Digestive Surgery, Antoine-Beclere Hospital, AP-HP, 92140, Clamart, France.

Purpose: We report an unusual case of endometriosis of the appendix with simultaneous invasion of the sigmoid colon.

Methods: Clinical, radiological, surgical, and histological data of the patient were reviewed, as well as the current literature on gastrointestinal endometriosis.

Results: A 41-year-old woman presented to the emergency department of our hospital with acute right lower quadrant pain, pronounced tenderness elevated white blood cell count, and increased C-reactive protein. Read More

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http://link.springer.com/10.1007/s00384-019-03242-0
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http://dx.doi.org/10.1007/s00384-019-03242-0DOI Listing
January 2019
3 Reads

Oncologic outcomes after adjuvant chemotherapy with capecitabine compared to 5-fluorouracil/leucovorin for geriatric stage II colon cancer: a retrospective cohort study.

Int J Colorectal Dis 2019 Jan 19. Epub 2019 Jan 19.

Department of Surgery, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, South Korea.

Purpose: After curative resection of stage II colon cancer, adjuvant chemotherapy with 5-fluorouracil/leucovorin (FL) or capecitabine is selectively recommended. However, there is little evidence of the effect of capecitabine on oncologic outcome in geriatric patients with stage II colon cancer compared to that of FL. The aim of this study was to determine the difference in recurrence-free survival (RFS), cancer-specific survival (CSS), and overall survival (OS) in patients older than 70 years of age with stage II colon cancer receiving capecitabine and FL. Read More

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http://dx.doi.org/10.1007/s00384-019-03237-xDOI Listing
January 2019
1 Read

D3 lymph node dissection reduces recurrence after primary resection for elderly patients with colon cancer.

Int J Colorectal Dis 2019 Jan 18. Epub 2019 Jan 18.

Department of Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan.

Purpose: The favorable oncological impact of D3 lymph node dissection after colon cancer surgery has been described previously. However, D3 lymph node dissection is potentially more invasive than conventional D2 lymph node dissection. The oncological merit of D3 lymph node dissection in elderly patients with colon cancer remains unclear. Read More

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http://dx.doi.org/10.1007/s00384-018-03233-7DOI Listing
January 2019

Colonic stenting as a bridge to surgery in malignant large bowel obstruction: oncological outcomes.

Int J Colorectal Dis 2019 Jan 16. Epub 2019 Jan 16.

Department of Colorectal Surgery, St James Hospital, Dublin 8, Ireland.

Introduction: Stenting of obstructing colorectal cancers obviates the need for emergency surgery, reducing initial morbidity and mortality rate associated with emergency surgery and facilitates full staging of the neoplastic process with an opportunity to optimize the patient for surgery. Some recent publications have suggested however that this approach may be associated with higher local recurrence rates. We examined our outcomes following colonic stenting as a bridge to resection. Read More

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http://dx.doi.org/10.1007/s00384-019-03239-9DOI Listing
January 2019
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Short-term outcomes of laparoscopic surgery for colorectal cancer in the elderly versus non-elderly: a systematic review and meta-analysis.

Int J Colorectal Dis 2019 Jan 16. Epub 2019 Jan 16.

Department of Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Purpose: Laparoscopic surgery for colorectal cancer has spread globally. The usefulness of laparoscopic surgery for elderly patients was initially indicated by comparison with open surgery. However, whether the procedure is safe for elderly as well as non-elderly patients with colorectal cancer remains unclear. Read More

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http://link.springer.com/10.1007/s00384-019-03234-0
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http://dx.doi.org/10.1007/s00384-019-03234-0DOI Listing
January 2019
4 Reads

A mini-invasive procedure for the treatment of supralevator abscess of cryptoglandular origin by extrasphincteric extension: preliminary results at 1-year follow-up.

Int J Colorectal Dis 2019 Jan 15. Epub 2019 Jan 15.

Department of Radiology, "S. Maria dei Battuti" Hospital, Via Brigata Bisagno 4, 31015, Conegliano, TV, Italy.

Aim: The aim of this retrospective study is to evaluate the preliminary results of a mini-invasive procedure for the treatment of supralevator abscesses (SLA) of cryptoglandular origin by extrasphincteric extension.

Method: In this clinical study, an innovative two-stage procedure was tested for the surgical treatment of SLA. As first step and as a preparation for surgery, the interventional radiologist positioned a CT-guided percutaneous perianal guidewire inside the abscess cavity under local anesthesia. Read More

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http://dx.doi.org/10.1007/s00384-019-03243-zDOI Listing
January 2019

A review of the effect of faecal incontinence and constipation on sexual function.

Int J Colorectal Dis 2019 Jan 11. Epub 2019 Jan 11.

The Sir Alan Parks Department of Physiology, St Mark's Hospital and Academic Institute, Watford Road, Harrow, HA1 3UJ, UK.

Aim: Faecal incontinence and constipation are common conditions which may adversely affect quality of life. They may have an adverse effect on sexual function.

Method: This review of the published literature aimed to assess the published evidence. Read More

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http://dx.doi.org/10.1007/s00384-018-03231-9DOI Listing
January 2019
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Surgery and chemotherapy are associated with improved overall survival in anal adenocarcinoma: results of a national cohort study.

Int J Colorectal Dis 2019 Jan 11. Epub 2019 Jan 11.

Division of Colon and Rectal Surgery, Mayo Clinic, 200 First St. Southwest, Rochester, MN, 55905, USA.

Purpose: Anal adenocarcinoma (AAC) is a rare disease with treatment protocols that mimic both that of rectal adenocarcinoma (RAC) and anal squamous cell carcinoma (ASCC). Due to its rarity, data regarding outcomes are lacking. We sought to determine outcomes of patients with AAC compared to RAC and ASCC and to evaluate risk factors for mortality in AAC. Read More

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http://dx.doi.org/10.1007/s00384-018-03232-8DOI Listing
January 2019
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Circulating tumor cells as an independent prognostic factor in advanced colorectal cancer: a retrospective study in 121 patients.

Int J Colorectal Dis 2019 Jan 10. Epub 2019 Jan 10.

Department of Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201999, China.

Purpose: This study aimed to evaluate the prognostic value of circulating tumor cells (CTCs) in advanced colorectal cancer (CRC) patients during chemotherapy course.

Methods: From January 2016 to September 2017, the clinicopathological variables, such as gender, age, tumor location, tumor de-differentiation, depth of invasion, lymphatic invasion, distant metastasis, TNM stage, CTCs enumeration during 2-6 cycles of chemotherapy, and serum carcinoembryonic antigen (CEA) level during the same period, of 121 newly acquired and histopathologically confirmed CRC patients were collected from the Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine. All patients were followed up for survival until the end of November 2018. Read More

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http://link.springer.com/10.1007/s00384-018-03223-9
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http://dx.doi.org/10.1007/s00384-018-03223-9DOI Listing
January 2019
2 Reads

Colorectal cancer screening by colonoscopy and trends in disease-specific mortality: a population-based ecological study of 358 German districts.

Int J Colorectal Dis 2019 Jan 10. Epub 2019 Jan 10.

Institute of Social Medicine and Epidemiology, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.

Purpose: Screening for colorectal cancer (CRC) by colonoscopy was implemented in Germany in 2002. Although the procedure has proven to be effective in reducing disease-specific mortality in numerous clinical studies, its effect at the population level is unclear. We performed an ecological study at the level of 358 German districts, testing the hypothesis that a higher participation rate in screening colonoscopy is associated with a stronger decline in CRC mortality from 2001 to 2012. Read More

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http://dx.doi.org/10.1007/s00384-018-03226-6DOI Listing
January 2019

Treatment patterns and survival outcomes for patients receiving second-line treatment for metastatic colorectal cancer in the USA.

Int J Colorectal Dis 2019 Jan 9. Epub 2019 Jan 9.

Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, 46285, USA.

Background: Colorectal cancer is the third most common cause of cancer death in the USA. It is important to identify patients who may experience poor outcomes from available treatments.

Methods: In this retrospective observational study, treatment patterns and survival outcomes were described among adult patients from the Flatiron Health electronic medical records database who were treated with at least two lines of therapy for metastatic colorectal cancer in the USA between January 2013 and May 2018. Read More

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http://link.springer.com/10.1007/s00384-018-03227-5
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http://dx.doi.org/10.1007/s00384-018-03227-5DOI Listing
January 2019
3 Reads

Patterns of bone metastases in newly diagnosed colorectal cancer: a real-world analysis in the SEER database.

Int J Colorectal Dis 2019 Jan 8. Epub 2019 Jan 8.

Department of Epidemiology and Biostatistics, First Affiliated Hospital, Army Medical University, 30 Gaotanyan Street Shapingba District, Chongqing, 400038, China.

Purpose: To investigate the incidence and the associated factors for bone metastases (BM) development and prognosis in initial colorectal cancer (CRC) with a large sample using Surveillance, Epidemiology, and End Results (SEER) cohort.

Methods: Primary CRC patients, who were initially diagnosed between 2010 and 2015 in the SEER database, were included to analyze BM incidence and risk factors for BM occurrence. The patients with at least 1-year follow-up were involved to investigate the prognostic factors for BM. Read More

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http://dx.doi.org/10.1007/s00384-018-3213-5DOI Listing
January 2019
2 Reads
2.449 Impact Factor

Appendicitis as a manifestation of colon cancer: should we image the colon after appendicectomy in patients over the age of 40 years?

Int J Colorectal Dis 2019 Jan 7. Epub 2019 Jan 7.

Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK.

Background: Appendicitis can be secondary to caecal pathology (polyp or cancer). Increasing age is a risk factor for malignancy coexisting with appendicitis. There is an increased coexistence of cancer post-appendicectomy in patients aged 50-54 years. Read More

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http://link.springer.com/10.1007/s00384-018-03224-8
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http://dx.doi.org/10.1007/s00384-018-03224-8DOI Listing
January 2019
6 Reads

Prognostic significance of inflammatory-related parameters in patients with anal canal cancer.

Int J Colorectal Dis 2019 Jan 7. Epub 2019 Jan 7.

Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Viale Regina Elena 326, 00161, Rome, Italy.

Purpose: To investigate the correlation between inflammatory-related parameters and overall survival (OS) and disease-free survival (DFS) in anal canal cancer population.

Methods And Materials: Patients diagnosed with anal canal carcinoma and treated with curative intent chemoradiotherapy (CRT) were included. Data about pre-treatment complete blood count were collected. Read More

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http://dx.doi.org/10.1007/s00384-018-03225-7DOI Listing
January 2019

Placement of SurgiWrap® adhesion barrier film around the protective loop stoma after laparoscopic colorectal cancer surgery may reduce the peristomal adhesion severity and facilitate the closure.

Int J Colorectal Dis 2019 Jan 7. Epub 2019 Jan 7.

Division of Colorectal Surgery, Department of Surgery, Kaohsiung Veteran General Hospital, 386 Ta-Chung 1st RD, Kaohsiung, Taiwan, 81346, Republic of China.

Purpose: A temporary loop stoma is often created after laparoscopic colorectal cancer surgery. Peristomal adhesions may make stoma closure into a complicated operation. We demonstrated how to place the SurgiWrap® adhesion barrier film and evaluated the peristomal adhesion severity and feasibility of stoma closure. Read More

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http://dx.doi.org/10.1007/s00384-018-03229-3DOI Listing
January 2019

The adipofasciocutaneous gluteal fold perforator flap a versatile alternative choice for covering perineal defects.

Int J Colorectal Dis 2019 Jan 4. Epub 2019 Jan 4.

Department of Plastic and Hand Surgery, Faculty of Medicine, University of Freiburg, im Breisgau, Germany.

Aim: Perineal defects following the resection of anorectal malignancies are a reconstructive challenge. Flaps based on the rectus abdominis muscle have several drawbacks. Regional perforator flaps may be a suitable alternative. Read More

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http://dx.doi.org/10.1007/s00384-018-03222-wDOI Listing
January 2019

Comparable perioperative outcomes, long-term outcomes, and quality of life in a retrospective analysis of ulcerative colitis patients following 2-stage versus 3-stage proctocolectomy with ileal pouch-anal anastomosis.

Int J Colorectal Dis 2019 Jan 4. Epub 2019 Jan 4.

Division of General and Gastrointestinal Surgery, Department of Surgery, Massachusetts General Hospital, 55 Fruit St, GRB-425, Boston, MA, 02114, USA.

Purpose: Many surgeons assume 3-stage ileal pouch-anal anastomosis (IPAA) is safer than 2-stage IPAA in patients with active ulcerative colitis (UC), although recent data suggest outcomes are comparable. This study aimed to compare perioperative complications, late complications, and functional outcomes after 2- versus 3-stage IPAA in patients with active UC.

Methods: A retrospective review was conducted of patients who underwent 2- or 3-stage IPAA for active UC from 2000 to 2015 in a high-volume institution. Read More

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http://dx.doi.org/10.1007/s00384-018-03221-xDOI Listing
January 2019

Long-term prognosis after treatment for T1 carcinoma of laterally spreading tumors: a multicenter retrospective study.

Int J Colorectal Dis 2019 Jan 3. Epub 2019 Jan 3.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

Purpose: Long-term prognosis of T1 laterally spreading tumors (LSTs) after treatment have not been clarified. This study compared clinicopathological characteristics and long-term prognosis of T1 LSTs.

Methods: We retrospectively assessed 169 patients with 169 T1 LSTs between January 1992 and December 2008 by ten hospitals. Read More

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http://dx.doi.org/10.1007/s00384-018-3203-7DOI Listing
January 2019

Persistent fecal incontinence into adulthood after repair of anorectal malformations.

Int J Colorectal Dis 2018 Dec 28. Epub 2018 Dec 28.

Department of Pediatric Surgery, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.

Purpose: Persistent fecal incontinence beyond childhood is common in ARM patients. The aim of this study was to analyze a consecutive series of adult patients with persistent incontinence, establish the causes, and evaluate whether further treatment could be offered.

Methods: Forty-four adult ARM patients with reported incontinence were invited. Read More

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http://dx.doi.org/10.1007/s00384-018-3220-6DOI Listing
December 2018
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Correction to: Mucosal advancement flap for recurrent complex anal fistula: a repeatable procedure.

Int J Colorectal Dis 2018 Dec 20. Epub 2018 Dec 20.

Proctology Unit, Service of Visceral Surgery, Geneva University Hospitals and Medical School, Geneva, Switzerland.

The name of the second author of this article was incorrectly presented as "Riccardo Scarpa Cosimo" this should have been "Cosimo Riccardo Scarpa". Read More

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http://link.springer.com/10.1007/s00384-018-3217-1
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http://dx.doi.org/10.1007/s00384-018-3217-1DOI Listing
December 2018
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Focus on current and future management possibilities in inflammatory bowel disease-related chronic pain.

Int J Colorectal Dis 2019 Feb 19;34(2):217-227. Epub 2018 Dec 19.

Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 6/8, 92-215, Lodz, Poland.

Introduction: Visceral pain is a symptom reported by over 70% of inflammatory bowel disease (IBD) sufferers. So far, a single, specific cause of this debilitating state has not been established. Chronic pain is one of the most important factors decreasing the quality of life in IBD course. Read More

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http://dx.doi.org/10.1007/s00384-018-3218-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331746PMC
February 2019

Totally robotic modified complete mesocolic excision and central vascular ligation for right-sided colon cancer: technical feasibility and mid-term oncologic outcomes.

Int J Colorectal Dis 2018 Dec 17. Epub 2018 Dec 17.

Department of Surgery, College of Medicine, Yonsei University, 50 Yonsei-ro, Seodaemun-Gu, Seoul, 120-752, South Korea.

Background: Recently, an operative strategy involving complete mesocolic excision (CME) and central vascular ligation (CVL) for colonic cancer has been introduced. We aimed to describe our initial experience and assess the long-term outcomes of robotic modified CME (mCME) and CVL (mCME+CVL) for right-sided colon cancer.

Methods: Of the 677 patients with histologically confirmed, right-sided colon adenocarcinoma who underwent curative mCME+CVL between February 2008 and October 2016, 43 who were treated entirely using the robotic approach were included in this retrospective study. Read More

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http://dx.doi.org/10.1007/s00384-018-3208-2DOI Listing
December 2018
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Quality of life following ostomy reversal with purse-string vs linear skin closure: a systematic review.

Int J Colorectal Dis 2019 Feb 13;34(2):209-216. Epub 2018 Dec 13.

Division of General Surgery, IRCCS Policlinico San Donato, Department of Biomedical Sciences of Health, University of Milan Medical School, San Donato Milanese, Milan, Italy.

Background: The importance of the defunctioning stoma on minimizing anastomotic leak in colorectal surgery is well established. However, a defunctioning stoma can substantially impact on quality of life (QoL). Circumferential purse-string approximation (PSA) and linear skin closure (LSC) are the most commonly performed surgical technique for reversal of stoma. Read More

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http://dx.doi.org/10.1007/s00384-018-3219-zDOI Listing
February 2019

Guideline recommendations for treatment of patients with inflammatory bowel diseases are not implemented in clinical practice-results of a non-representative survey.

Int J Colorectal Dis 2018 Dec 7. Epub 2018 Dec 7.

Medizinische Klinik m. S. Gastroenterologie, Infektiologie und Rheumatologie, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Hindenburgdamm 30, 12200, Berlin, Germany.

Purpose: There is a growing evidence for over-, under-, or misuse of health care in patients with inflammatory bowel disease. Most studies looked at treatment variability or used quality measures, which mostly capture supportive interventions rather than treatment of IBD in itself. We aimed to evaluate if current recommendations in clinical practice guidelines regarding the medical treatment of patients with inflammatory bowel diseases are being followed in Germany. Read More

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http://dx.doi.org/10.1007/s00384-018-3215-3DOI Listing
December 2018
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The growing discrepancy between resident training in colonic surgery and the rising number of general surgery graduates.

Int J Colorectal Dis 2018 Dec 6. Epub 2018 Dec 6.

Department of Surgery, University Hospital Zurich, Rämistrasse 100, CH-8091, Zürich, Switzerland.

Purpose: The decrease in resident operative experience due to working-hour directives and sub-specialization within general surgery is the subject of growing debate. This study aims to examine how the numbers of colectomies used for resident training have evolved since the introduction of working-hour directives and to place these results within the context of the number of new general surgeons.

Methods: Based on the nationwide database of the Swiss association for quality management in surgery, all segmental colectomies performed at 86 centers were analyzed according to the presence or absence of residents and compared to national numbers of surgical graduates. Read More

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http://dx.doi.org/10.1007/s00384-018-3209-1DOI Listing
December 2018

Probiotics for preventing postoperative infection in colorectal cancer patients: a systematic review and meta-analysis.

Int J Colorectal Dis 2018 Dec 11. Epub 2018 Dec 11.

Center for Disease Prevention and Control of Beijing Military Region, Beijing, 100042, China.

Purpose: Postoperative infection has seriously affected the prognosis of cancer patients, while probiotics have been increasingly used to prevent postoperative infection in clinical practice. This study aimed to evaluate the preventive effect of probiotics on infection after colorectal cancer (CRC) surgery.

Methods: Related clinical trial reports were collected from Pubmed, Embase, Cochrane Library as well as China National Knowledge Infrastructure (CNKI) databases. Read More

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http://dx.doi.org/10.1007/s00384-018-3214-4DOI Listing
December 2018