1,282 results match your criteria International Journal of Clinical Pharmacy[Journal]


Community pharmacists' role in preventing opioid substitution therapy-related deaths: a qualitative investigation into current UK practice.

Int J Clin Pharm 2019 Feb 15. Epub 2019 Feb 15.

Department of Pharmacy and Pharmacology, University of Bath, C/O: 5 West 3.26, Claverton Down, Bath, BA2 7AY, UK.

Background Opioid substitution therapy involves prescribing of medical substitutes like methadone and buprenorphine to patients who are addicted to opioids. The majority of opioid substitution therapy dispensing in the UK is done by community pharmacists and they often see the patients on daily basis. It is unknown to what extent community pharmacists implement the policy to prevent overdose in patients receiving such treatment. Read More

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http://dx.doi.org/10.1007/s11096-019-00790-xDOI Listing
February 2019

Hospitalization period and direct medical cost in patients using warfarin or novel oral anti-coagulants after a cerebral embolism.

Int J Clin Pharm 2019 Feb 5. Epub 2019 Feb 5.

Pharmacy Management Institute, 25-17, Sakuragaoka-cho, Shibuya-ku, Tokyo, 150-0031, Japan.

Background Warfarin has been used in Japan for a long time in patients after cerebral embolism to prevent recurrence. Recently, several novel oral anti-coagulants (NOACs) have been approved for use and are gradually replacing warfarin. However, it remains unclear whether warfarin and other NOACs differ from each other with respect to drug costs and length of stay (LOS) during treatment in Japan. Read More

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http://dx.doi.org/10.1007/s11096-019-00792-9DOI Listing
February 2019
1 Read

Factors associated with patient preferences towards deprescribing: a survey of adult patients on prescribed medications.

Int J Clin Pharm 2019 Feb 5. Epub 2019 Feb 5.

Department of Healthcare Epidemiology, School of Public Health in the Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto, 606-8501, Japan.

Background Deprescribing is a patient-centered intervention with inherent uncertainties and requires shared decision making and patient involvement. Objective In the present study, we aimed to investigate factors associated with patient preferences toward deprescribing in a representative sample in Japan. Methods We conducted a nationwide cross-sectional survey and used a quota sampling method to select representative samples of the Japanese general population. Read More

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http://dx.doi.org/10.1007/s11096-019-00797-4DOI Listing
February 2019
1 Read

Off-label use of tamoxifen in a Chinese tertiary care hospital.

Int J Clin Pharm 2019 Jan 25. Epub 2019 Jan 25.

Department of Pharmacy, Xiamen Maternity and Child Health Care Hospital, No. 10 Zhenhai Road, Xiamen, 361001, Fujian Province, China.

Background Tamoxifen is an estrogen receptor modulator used for the treatment of breast cancer; however, currently, it is used in many off-label indications. Objective To investigate the prevalence of tamoxifen off-label prescribing and explore available scientific evidence that supports those uses in outpatients. Setting Xiamen maternity and child health care hospital in Xiamen city of China. Read More

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http://dx.doi.org/10.1007/s11096-019-00788-5DOI Listing
January 2019
1 Read

Polypharmacy in older patients at primary care units in Brazil.

Int J Clin Pharm 2019 Jan 25. Epub 2019 Jan 25.

Programa de Mestrado em Saúde Coletiva, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Rua Rio de Contas 58, Quadra 17, Lote 58, Candeias, Vitória da Conquista, Bahia, 45055-090, Brazil.

Background Despite extensive studies of polypharmacy in older patients, no consensus regarding the definition of this practice exists in the literature. Several studies have defined polypharmacy as problematic when considering only the numbers of medications used by patients. Objective This study aimed to assess the prevalence of polypharmacy prescribing by comparing two different definitions (quantitative and qualitative) and evaluating factors associated with this practice in older patients. Read More

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http://dx.doi.org/10.1007/s11096-018-00780-5DOI Listing
January 2019

Usefulness of STOPP/START criteria to assess appropriateness of medicines prescribed to older adults in a resource-limited setting.

Int J Clin Pharm 2019 Jan 22. Epub 2019 Jan 22.

Department of Pharmacology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.

Background There is a dearth of published data from resource-limited settings on appropriateness of medicines in older adults using explicit criteria, but it is unclear if the STOPP/START criteria can be helpful. Objective To assess the usefulness of STOPP/START criteria in assessing appropriateness of medicines in a resource-limited setting. Setting Medical, diabetic and psychiatric clinics of a tertiary care hospital and elderly living in a selected locality in Colombo district. Read More

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http://dx.doi.org/10.1007/s11096-019-00786-7DOI Listing
January 2019

Pharmacist-led academic detailing intervention in primary care: a mixed methods feasibility study.

Int J Clin Pharm 2019 Jan 22. Epub 2019 Jan 22.

Pharmaceutical Care Research Group, Cavanagh Pharmacy Building, School of Pharmacy, University College Cork, College Road, Cork, Republic of Ireland.

Background Academic detailing is a form of continuing medical education in which a trained health professional such as a physician or pharmacist visits prescribers in their practice to provide evidence-based information. While academic detailing has been adopted in other countries, this strategy is not routinely used in Ireland. Objective The aim of this study was to assess the feasibility and acceptability to General Practitioners (GPs) of a pharmacist-led academic detailing intervention in Ireland. Read More

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http://dx.doi.org/10.1007/s11096-019-00787-6DOI Listing
January 2019
1 Read

Utilization of venous thromboembolism prophylaxis in American hospitalized pregnant women undergoing cesarean section.

Int J Clin Pharm 2019 Feb 19;41(1):264-271. Epub 2019 Jan 19.

Department of Obstetrics and Gynecology, University of California, Davis Medical Center, 2315 Stockton Blvd, Sacramento, CA, 95817, USA.

Background Pregnancy-related venous thromboembolism (VTE) is a leading preventable cause of maternal mortality in the United States; however, American guidelines for pharmacologic VTE prophylaxis remain less aggressive than other developed countries. The Safe Motherhood Initiative (SMI) combines aspects of American and international guidelines to increase utilization of prophylaxis and thereby decrease incidence of pregnancy-related VTE. Objectives To evaluate the prescribing and administration rates of pharmacologic VTE prophylaxis for women undergoing cesarean section (c-section) when retrospectively applying the SMI recommendations. Read More

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http://dx.doi.org/10.1007/s11096-018-00779-yDOI Listing
February 2019
2 Reads

Cost-effective analysis of low- versus high-dose colistin in the treatment of multi-drug resistant pneumonia in Saudi Arabia.

Int J Clin Pharm 2019 Feb 19;41(1):1-2. Epub 2019 Jan 19.

Skaggs School of Pharmacy and Pharmaceutical Science, University of California San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1007/s11096-019-00783-wDOI Listing
February 2019

Comparative efficacy of ivabradine versus beta-blockers in patients with mitral stenosis in sinus rhythm: systematic review and meta-analysis.

Int J Clin Pharm 2019 Feb 18;41(1):22-29. Epub 2019 Jan 18.

Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.

Background Patients with mitral valve stenosis have increased heart rate. HR reduction is known as an important treatment and therapy strategy for patients with mitral valve stenosis. Aim of the review The aim of this systematic review and meta-analysis was to compare the efficacy of ivabradine versus beta-blockers in patients with mitral stenosis in sinus rhythm. Read More

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http://dx.doi.org/10.1007/s11096-018-00778-zDOI Listing
February 2019
1 Read

DEFEAT-polypharmacy: deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities.

Int J Clin Pharm 2019 Feb 18;41(1):167-178. Epub 2019 Jan 18.

University of Bath, Bath, Somerset, UK.

Background Prolonged use of anticholinergic and sedative medicines is correlated with worsening cognition and physical function decline. Deprescribing is a proposed intervention that can help to minimise polypharmacy whilst potentially improving several health outcomes in older people. Objective This study aimed to examine the feasibility of implementing a deprescribing intervention that utilises a patient-centred pharmacist-led intervention model; in order to address major deprescribing challenges such as general practitioner time constraints and lack of accessible deprescribing guidelines and processes. Read More

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http://dx.doi.org/10.1007/s11096-019-00784-9DOI Listing
February 2019

Perceived roles and barriers in caring for the people who are homeless: a survey of UK community pharmacists.

Int J Clin Pharm 2019 Feb 18;41(1):215-227. Epub 2019 Jan 18.

School of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen, UK.

Background Community pharmacists can be an accessible source for advice and support for the people who are homeless, given their utilisation of a variety of currently available services such as dispensing of medicines, drugs and alcohol services. Objective To determine community pharmacists' training, experiences and behavioural determinants in counselling and management of homeless population. Setting UK community pharmacies. Read More

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http://dx.doi.org/10.1007/s11096-019-00789-4DOI Listing
February 2019

Infectious diseases physician attitudes to long-term antibiotic use.

Int J Clin Pharm 2019 Feb 17;41(1):18-21. Epub 2019 Jan 17.

Monash Health, Clayton, VIC, Australia.

Background In Australia, it is not known how much antibiotic prescribing by infectious diseases physicians is long-term, or how confident they are with the evidence behind this practice. Objective Survey Australian infectious diseases physicians to assess attitudes and prescribing practice prescribing prolonged courses of antibiotics. Methods An online questionnaire was distributed to the mailing group for the Australian Society of Infectious Diseases. Read More

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http://dx.doi.org/10.1007/s11096-018-00781-4DOI Listing
February 2019

The clinical effects of CYP2C19 *2 allele frequency on Palestinian patients receiving clopidogrel after percutaneous coronary intervention.

Int J Clin Pharm 2019 Feb 17;41(1):96-103. Epub 2019 Jan 17.

Faculty of Medicine, the Islamic University of Gaza, Gaza, Palestine.

BackgroundCYP2C19 loss-of-function polymorphic alleles (*2 and *3) have been documented to impair clopidogrel metabolism, and represent a risk factor for major adverse cardiac events. CYP2C19 polymorphism exhibits marked ethnic heterogeneity. Objective To determine the prevalence of CYP2C19 *2 and *3 alleles in a cohort of Palestinian patients managed with percutaneous coronary intervention and dual antiplatelet therapy, and to determine their role in causing major adverse cardiac events. Read More

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http://link.springer.com/10.1007/s11096-018-00782-3
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http://dx.doi.org/10.1007/s11096-018-00782-3DOI Listing
February 2019
4 Reads

Identify and categorize drug-related problems in hospitalized surgical patients in China.

Int J Clin Pharm 2019 Feb 4;41(1):13-17. Epub 2019 Jan 4.

Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuanjiagang, Yuzhong District, Chongqing, China.

Background Data is lacking on types and severities of drug-related problems (DRPs) in hospitalized surgical patients in China. Objective To identify and categorize types and causes of DRPs, and to assess severities of these DRPs. Setting An academic teaching hospital in Chongqing, China. Read More

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http://link.springer.com/10.1007/s11096-018-0777-7
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http://dx.doi.org/10.1007/s11096-018-0777-7DOI Listing
February 2019
2 Reads

Bevacizumab and erlotinib versus bevacizumab for colorectal cancer treatment: systematic review and meta-analysis.

Int J Clin Pharm 2019 Feb 4;41(1):30-41. Epub 2019 Jan 4.

Prevention Center of Social-Mental Injuries, Ilam University of Medical Sciences, Ilam, Iran.

Background Improving the survival of patients diagnosed with metastatic colorectal cancer requires the use of chemotherapy to be managed with minimum adverse effects. Randomized control trials (RCTs) have shown promising results with a combination of bevacizumab and erlotinib to block two important tumor growth pathways, namely vascular endothelial growth factor and epidermal growth factor receptor. Aim of the Review We aimed to examine the efficacy and safety of the combination of bevacizumab and erlotinib with bevacizumab alone in the maintenance treatment of metastatic colorectal cancer, by examining PFS, OS, overall response rate (ORR), and toxicity. Read More

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http://dx.doi.org/10.1007/s11096-018-0754-1DOI Listing
February 2019
4 Reads

Pain control using liposomal bupivacaine versus bupivacaine for robotic assisted thoracic surgery.

Int J Clin Pharm 2019 Feb 4;41(1):258-263. Epub 2019 Jan 4.

BJD School of Pharmacy, Shenandoah University, 1775 N Sector Ct, Winchester, VA, 22601, USA.

Background Despite a trend towards minimally invasive thoracic surgeries over thoracotomies, patients can still experience significant post-operative pain. Literature on the use of liposomal bupivacaine in patients undergoing robotic surgeries is lacking. Objective To compare pain control via intercostal nerve block with liposomal bupivacaine to bupivacaine for patients undergoing robotic assisted thoracic surgery. Read More

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http://link.springer.com/10.1007/s11096-018-0776-8
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http://dx.doi.org/10.1007/s11096-018-0776-8DOI Listing
February 2019
9 Reads

Potential inappropriate prescribing and associated factors among older persons in Nigeria and South Africa.

Int J Clin Pharm 2019 Feb 4;41(1):207-214. Epub 2019 Jan 4.

Discipline of Pharmaceutical Sciences, College of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4000, South Africa.

Background Potential inappropriate prescribing (PIP) among older persons is a global public health issue. However, trans-country data that can influence interventions on a global or regional level is scarce. Objectives To compare the prevalence of PIP and to determine the associated factors among older Nigerians and South Africans. Read More

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http://dx.doi.org/10.1007/s11096-018-0770-1DOI Listing
February 2019

Impact of hospital pharmacist interventions on the combination of citalopram or escitalopram with other QT-prolonging drugs.

Int J Clin Pharm 2019 Feb 4;41(1):42-48. Epub 2019 Jan 4.

Pharmacy Department, Groupe hospitalier Paris Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France.

Background Citalopram and escitalopram can both induce dose-dependent QT prolongation. The risk of arrhythmia may be increased with concomitant use of other drugs that induce QT prolongation. Objective To evaluate the prevalence and impact of pharmacist interventions on the combination of citalopram or escitalopram with other drugs that induce QT prolongation. Read More

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http://dx.doi.org/10.1007/s11096-018-0724-7DOI Listing
February 2019

Clinical experience with the etanercept biosimilar SB4 in psoriatic patients.

Int J Clin Pharm 2019 Feb 4;41(1):9-12. Epub 2019 Jan 4.

Department of Surgery and Translational Medicine, Section of Dermatology, University of Florence, Ospedale Piero Palagi, viale Michelangelo 41, 50125, Florence, Italy.

Background After the expiry of the patent of reference etanercept, several biosimilars have been developed, including SB4. Objective To study safety and efficacy of SB4 in psoriatic patients previously treated with etanercept and in the etanercept naive ones. Method Patients affected by moderate to severe psoriasis and/or psoriatic arthritis attending the Psoriasis Center of Florence University, treated with SB4 were enrolled in the study. Read More

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http://link.springer.com/10.1007/s11096-018-0769-7
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http://dx.doi.org/10.1007/s11096-018-0769-7DOI Listing
February 2019
6 Reads

The impact of a pharmacist on post-take ward round prescribing and medication appropriateness.

Int J Clin Pharm 2019 Feb 4;41(1):65-73. Epub 2019 Jan 4.

Pharmacy Department, Royal Brisbane and Women's Hospital, Cnr Butterfield St and Bowen Bridge Rd, Herston, QLD, 4029, Australia.

Background Medication communication and prescribing on the post-take ward round following patient admission to hospital can be suboptimal leading to worse patient outcomes. Objective To evaluate the impact of clinical pharmacist participation on the post-take ward round on the appropriateness of medication prescribing, medication communication, and overall patient health care outcomes. Setting Tertiary referral teaching hospital, Brisbane, Australia. Read More

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http://link.springer.com/10.1007/s11096-018-0775-9
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http://dx.doi.org/10.1007/s11096-018-0775-9DOI Listing
February 2019
1 Read

Abuse of sulfonylureas: Is factitious hypoglycemia a cause for concern?

Int J Clin Pharm 2019 Feb 4;41(1):3-5. Epub 2019 Jan 4.

Public Health Institute, Liverpool John Moores University, Liverpool, UK.

Several prescription and nonprescription drugs are liable for abuse. However, oral hypoglycemic agents are among the most benign and low-risk drugs in terms of abuse liability. This commentary intends to raise awareness regarding the abuse of a particular type of oral hypoglycemic agent, namely sulfonylurea drugs, used to experience mental-altering effects for its euphoric "hypoglycemic rush. Read More

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http://link.springer.com/10.1007/s11096-018-0767-9
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http://dx.doi.org/10.1007/s11096-018-0767-9DOI Listing
February 2019
6 Reads

Adaptation and validation of PCNE drug-related problem classification v6.2 in French-speaking Belgian community pharmacies.

Int J Clin Pharm 2019 Feb 4;41(1):244-250. Epub 2019 Jan 4.

Department of Pharmacotherapy and Pharmaceutics, Faculty of Pharmacy, Université libre de Bruxelles (ULB), Boulevard du Triomphe, CP 207, Access 2, Campus de la Plaine, Building BC, Local 1B7 101, 1050, Brussels, Belgium.

Background Many tools exist to document drug-related problems (DRP), such as the Pharmaceutical Care Network Europe (PCNE) classification. However, none have been adapted and published for French-speaking Belgian community pharmacies. Settings French-speaking Belgian Community pharmacies. Read More

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http://link.springer.com/10.1007/s11096-018-0773-y
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http://dx.doi.org/10.1007/s11096-018-0773-yDOI Listing
February 2019
1 Read

Assessment tool for hospital admissions related to medications: development and validation in older patients.

Int J Clin Pharm 2019 Feb 26;41(1):198-206. Epub 2018 Dec 26.

Hospital Pharmacy Department, Uppsala University Hospital, Uppsala, Sweden.

Background Medication-related hospital admissions (MRAs) are frequently used to measure outcomes in studies involving medication reviews. The process of identifying MRAs is subjective and time-consuming, and practical, validated alternatives are required. Objective The aim of this study was to develop and validate a practical tool to identify MRAs. Read More

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http://link.springer.com/10.1007/s11096-018-0768-8
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http://dx.doi.org/10.1007/s11096-018-0768-8DOI Listing
February 2019
1 Read

A multicentre observational study of the effectiveness, safety and economic impact of nivolumab on non-small-cell lung cancer in real clinical practice.

Int J Clin Pharm 2019 Feb 22;41(1):272-279. Epub 2018 Dec 22.

Hospital Pharmacy Department, Hospital Juan Ramón Jiménez, Huelva, Spain.

Background Immunotherapy has become a standard treatment for lung cancer; however, the high cost makes it necessary to assess health outcomes. Objective The aim of this study was to evaluate the effectiveness, safety and economic cost of nivolumab in real-world clinical practice. Setting Fifteen regional and academic hospitals from Spain participated in this study. Read More

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http://dx.doi.org/10.1007/s11096-018-0772-zDOI Listing
February 2019
4 Reads

Hassles with medication management perceived by caregivers of adults who have intellectual or developmental disabilities.

Int J Clin Pharm 2019 Feb 22;41(1):131-140. Epub 2018 Dec 22.

College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, MI, 48109-1065, USA.

Background Medication management is undertaken by caregivers of people who have intellectual or developmental disabilities. Objective The objectives were to measure the medication management hassles reported by caregivers of adults who have intellectual or developmental disabilities and to describe associations between characteristics of caregivers, medication regimens, and the person with intellectual or developmental disability and the scale score. Setting Web-based survey conducted in the United States. Read More

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http://link.springer.com/10.1007/s11096-018-0771-0
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http://dx.doi.org/10.1007/s11096-018-0771-0DOI Listing
February 2019
1 Read

Exploring influences on pharmacists' and students' ethical reasoning in a changing practice landscape in Australia.

Int J Clin Pharm 2019 Feb 22;41(1):280-288. Epub 2018 Dec 22.

School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, Curtin University, Perth, WA, Australia.

Background Practising pharmacists continuously develop their ethical reasoning skills, which evolve with practice experience and exposure to challenging scenarios. Considering the recent expansion of the roles of pharmacists and the paradigm shift in pharmacy practice, it is timely to explore community pharmacists' attitudes regarding the importance of ethics and their ethical reasoning. Objective To explore underlying factors influencing community pharmacists' and pharmacy students' ethical reasoning and attitudes towards pharmacy ethics, ethical reasoning processes and perceived current dilemmas. Read More

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http://dx.doi.org/10.1007/s11096-018-0774-xDOI Listing
February 2019
1 Read

South Asians living in the UK and adherence to coronary heart disease medication: a mixed- method study.

Int J Clin Pharm 2019 Feb 18;41(1):122-130. Epub 2018 Dec 18.

Department of Practice and Policy, School of Pharmacy, University College London, London, UK.

Background The prevalence of coronary heart disease amongst South Asian population in the UK is higher compared to the general population. Objective This study sought to investigate beliefs and experiences of South Asian patients regarding coronary heart disease and medication taking behaviour. Setting A London Heart Attack Centre. Read More

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http://link.springer.com/10.1007/s11096-018-0760-3
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http://dx.doi.org/10.1007/s11096-018-0760-3DOI Listing
February 2019
3 Reads

Impact of medication therapy management on pharmacotherapy safety in an intensive care unit.

Int J Clin Pharm 2019 Feb 15;41(1):179-188. Epub 2018 Dec 15.

Laboratório de Pesquisa em Ensino e Serviços de Saúde (LaPESS), Faculdade de Farmácia, Universidade Federal de Goiás - UFG, 240th street corner of 5th Avenue, Goiânia, GO, 74650-170, Brazil.

Background Drug-related problems are mostly preventable or predictable circumstances that may impact on health outcomes. Clinical pharmacy activities such as medication therapy management can identify and solve these problems, with potential to improve medication safety and effectiveness. Objective To evaluate ability of medication therapy management service to detect drug-related problems and prevent adverse drug events. Read More

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http://link.springer.com/10.1007/s11096-018-0763-0
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http://dx.doi.org/10.1007/s11096-018-0763-0DOI Listing
February 2019
5 Reads

Colistin and polymyxin B for treatment of nosocomial infections in intensive care unit patients: pharmacoeconomic analysis.

Int J Clin Pharm 2019 Feb 15;41(1):74-80. Epub 2018 Dec 15.

Faculty of Pharmaceutical Sciences, University of Campinas (UNICAMP), Cândido Portinari 200, 13083-871, Campinas, SP, Brazil.

Background The emergence and rapid spread of multidrug-resistant gram-negative bacteria related to nosocomial infections is a growing worldwide problem, and polymyxins have become important due to the lack of new antibiotics. Objectives To evaluate the outcomes and pharmacoeconomic impact of using colistin and polymyxin B to treat nosocomial infections. Setting Neurosurgical, cardiovascular, or transplantation intensive care unit (ICU) at the Clinical Hospital of the University of Campinas (São Paulo, Brazil). Read More

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http://link.springer.com/10.1007/s11096-018-0766-x
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http://dx.doi.org/10.1007/s11096-018-0766-xDOI Listing
February 2019
1 Read

Awareness and use of medication management services in relation to medication adherence prior to hospitalisation among older adults in Regional Australia.

Int J Clin Pharm 2019 Feb 11;41(1):189-197. Epub 2018 Dec 11.

Maryborough Hospital Pharmacy, Wide Bay Hospital and Health Service, 185 Walker Street, Maryborough, QLD, 4650, Australia.

Background Ageing is associated with changes in physiology, functional ability, declined in cognition and multiple co-morbidities. Alterations in pharmacodynamic and pharmacokinetic aspects also occur. Medications can improve the quality of life in people with multiple co-morbidities; polypharmacy and ageing could increase risks of medication misadventures and adverse events leading to hospital admissions. Read More

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http://dx.doi.org/10.1007/s11096-018-0765-yDOI Listing
February 2019

Contributing factors to outpatient pharmacy near miss errors: a Malaysian prospective multi-center study.

Int J Clin Pharm 2019 Feb 30;41(1):237-243. Epub 2018 Nov 30.

Pharmacy Department, Hospital Seberang Jaya, Perai, Penang, Malaysia.

Background Detecting errors before medication dispensed or 'near misses' is a crucial step to combat the incidence of dispensing error. Despite this, no published evidence available in Malaysia relating to these issues. Objective To determine the incidence of medication labeling and filling errors, frequency of each type of the errors and frequency of the contributing factors at the final stage before dispensing. Read More

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http://dx.doi.org/10.1007/s11096-018-0762-1DOI Listing
February 2019

"Bite-sized" rivaroxaban patient education and its effect on knowledge.

Int J Clin Pharm 2019 Feb 5;41(1):6-8. Epub 2018 Dec 5.

Department of Pharmacy Practice, Wayne State University and St. John Hospital and Medical Center, 259 Mack Avenue, Detroit, MI, 48201, USA.

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http://dx.doi.org/10.1007/s11096-018-0764-zDOI Listing
February 2019

The association between polypharmacy and late life deficits in cognitive, physical and emotional capability: a cohort study.

Int J Clin Pharm 2019 Feb 29;41(1):251-257. Epub 2018 Nov 29.

Aberdeen Biomedical Imaging Centre, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK.

Background Polypharmacy is a growing health concern for older adults and is associated with poorer clinical outcome. Objective This study aim is to investigate the association between polypharmacy and impairment in cognitive, physical and emotional capability controlling for the confounding effect of co-morbidities. Setting The Aberdeen 1936 Birth Cohort from 1999 to 2004. Read More

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http://dx.doi.org/10.1007/s11096-018-0761-2DOI Listing
February 2019

Counseling patients on correct drug handling in German community pharmacies: experiences and opinions of pharmaceutical staff.

Int J Clin Pharm 2019 Feb 29;41(1):151-158. Epub 2018 Nov 29.

Drug Safety Center and Dept. of Clinical Pharmacy, Leipzig University, Brüderstraße 32, 04103, Leipzig, Germany.

Background For a safe drug therapy, outpatients have to self-administer their medications correctly. However, these procedures are known as error-prone. In community pharmacies, the pharmaceutical staff has to recognize patients' counseling needs and to use adequate strategies to prevent possible handling errors. Read More

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http://link.springer.com/10.1007/s11096-018-0757-y
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http://dx.doi.org/10.1007/s11096-018-0757-yDOI Listing
February 2019
1 Read

Correction to: Development of a tool for benchmarking of clinical pharmacy activities.

Int J Clin Pharm 2018 Dec;40(6):1624

Pharmacy Department, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, Brussels, Belgium.

In the original publication of an article, the corresponding author name has been swapped. Now the correct name has been published in this correction. Read More

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http://link.springer.com/10.1007/s11096-018-0741-6
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http://dx.doi.org/10.1007/s11096-018-0741-6DOI Listing
December 2018
4 Reads

Impact of deprescribing rounds on discharge prescriptions: an interventional trial.

Int J Clin Pharm 2019 Feb 27;41(1):159-166. Epub 2018 Nov 27.

Faculty of Pharmaceutical Sciences, The University of British Columbia, 2405 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.

Background Successful deprescribing practices are required to address issues associated with polypharmacy but are hindered by minimal interprofessional collaboration, time constraints, concern for negative outcomes, and absence of a systematic and evidence-based approach. Objective Determine the impact of pharmacist-led deprescribing rounds within a clinical teaching unit (CTU) the number of home medications discontinued upon hospital discharge. Setting Canadian tertiary care hospital. Read More

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http://link.springer.com/10.1007/s11096-018-0753-2
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http://dx.doi.org/10.1007/s11096-018-0753-2DOI Listing
February 2019
15 Reads

Evaluation of a hypertension-based patient education program in a stroke center.

Int J Clin Pharm 2018 Dec 26;40(6):1490-1500. Epub 2018 Nov 26.

Neurology Department, Groupe hospitalier Paris Saint-Joseph, Paris, France.

Background The benefits of educational programs are recognized in chronic diseases. An education program was designed in our hospital, for hypertensive patients after an acute episode of stroke to prevent stroke recurrence. Objective Evaluate the effects of such program on patient knowledge and blood pressure management. Read More

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http://link.springer.com/10.1007/s11096-018-0745-2
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http://dx.doi.org/10.1007/s11096-018-0745-2DOI Listing
December 2018
7 Reads

Patients' experiences with multidose drug dispensing: a cross sectional study.

Int J Clin Pharm 2019 Feb 26;41(1):104-112. Epub 2018 Nov 26.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University Utrecht, Utrecht, The Netherlands.

Background Automated multidose drug dispensing is used to support patients with their medication management. Though multidose drug dispensing systems are frequently used, little is known about patients' experiences with multidose drug dispensing systems. Objective To explore patients' experiences with the initiation and use of multidose drug dispensing systems. Read More

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http://dx.doi.org/10.1007/s11096-018-0749-yDOI Listing
February 2019
13 Reads

Translation and validation of a tool to assess the impact of clinical pharmacists' interventions.

Int J Clin Pharm 2019 Feb 26;41(1):56-64. Epub 2018 Nov 26.

Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.

Background The tool CLEO in French language is designed for estimating the potential relevance of pharmacists' interventions (PIs) in three independent dimensions with regard to process-related, clinical, economic, and humanistic impact. Objective We aimed to translate CLEO into German (CLEO), to demonstrate its feasibility in daily practice, and to validate the German version. Setting Convenience sample of three Swiss hospitals with established clinical pharmacy services. Read More

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http://dx.doi.org/10.1007/s11096-018-0755-0DOI Listing
February 2019
13 Reads

Systematic review and network meta-analysis of treatment for moderate-to-severe ulcerative colitis.

Int J Clin Pharm 2018 Dec 26;40(6):1411-1419. Epub 2018 Nov 26.

Health Science, Universidad San Jorge, Autovía Mudéjar, km. 299, 50830, Villanueva de Gállego, Zaragoza, Spain.

Background Biological drugs for moderate-to-severe ulcerative colitis have changed the therapeutic perspective, while small-molecule inhibitors and new promising drugs suggest new options. Aim Assess comparative efficacy and safety of biological and new small oral drugs: commercialized and under-investigation ones for patients naïve to biological drugs. Methods A systematic review was conducted to identify the randomized clinical trials phase 2 or 3, in adults with moderate-to-severe ulcerative colitis treated with biological drugs (infliximab, adalimumab, golimumab, vedolizumab and etrolizumab) or new oral small molecules (tofacitinib and ozanimod) as first line. Read More

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http://link.springer.com/10.1007/s11096-018-0743-4
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http://dx.doi.org/10.1007/s11096-018-0743-4DOI Listing
December 2018
9 Reads

The impact of generics and generic reference pricing on candesartan and rosuvastatin utilisation, price and expenditure in South Africa.

Int J Clin Pharm 2019 Feb 26;41(1):81-87. Epub 2018 Nov 26.

Discipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal (Westville Campus), Private Bag X54001, Durban, KwaZulu-Natal, 4000, South Africa.

Background In the South African private sector context, generically similar products are grouped together and the reimbursement rate is set at the average price of the generically equivalent products. Very little evidence exists in low and middle-income countries with regards to the impact of this policy over time. Objectives To determine the impact of the introduction of generics and generic reference pricing on candesartan and rosuvastatin in the South African private health care sector in terms of medicine utilisation, medicine price and medicine expenditure. Read More

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http://link.springer.com/10.1007/s11096-018-0758-x
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http://dx.doi.org/10.1007/s11096-018-0758-xDOI Listing
February 2019
6 Reads

The treatment-related experiences of parents, children and young people with regular prescribed medication.

Int J Clin Pharm 2019 Feb 26;41(1):113-121. Epub 2018 Nov 26.

Aston Pharmacy School, Aston University, Birmingham, UK.

Background Taking regular medication has been shown to have an impact on the daily lives of patients and their families. Objective To explore the medication-related experiences of patients and their families when a child or young person is prescribed regular medication. Setting A specialist U. Read More

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http://link.springer.com/10.1007/s11096-018-0756-z
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http://dx.doi.org/10.1007/s11096-018-0756-zDOI Listing
February 2019
9 Reads

The impact of an infectious disease expert team on outpatient parenteral antimicrobial treatment in the Netherlands.

Int J Clin Pharm 2019 Feb 26;41(1):49-55. Epub 2018 Nov 26.

Department of Internal Medicine, Haga Teaching Hospital, The Hague, The Netherlands.

Background There is increasing interest in outpatient parenteral antimicrobial treatment. Objective To evaluate the added value of consultation of an infectious diseases expert team (consisting of two internist-infectious diseases specialists and a microbiologist) for advice regarding type, administration route and duration of antibiotic treatment. Setting A retrospective case series was performed at the Haga Teaching Hospital, a 700-bed regional teaching hospital in The Hague, The Netherlands. Read More

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http://link.springer.com/10.1007/s11096-018-0751-4
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http://dx.doi.org/10.1007/s11096-018-0751-4DOI Listing
February 2019
7 Reads

Knowledge of cardiovascular disease risk factors and practice of primary prevention of cardiovascular disease by Community Pharmacists in Nigeria: a cross-sectional study.

Int J Clin Pharm 2018 Dec 26;40(6):1587-1595. Epub 2018 Nov 26.

Department of Medicine, College of Medicine, University of Lagos, Nigeria, Lagos, Nigeria.

Background Studies in international literature have shown that Community Pharmacists can make considerable impact in controlling cardiovascular disease risk factors, especially hypertension. In Nigeria, there are no studies on the knowledge of CVD risk factors by Community Pharmacists and their practice of primary prevention. Objective To assess the knowledge of CVD risk factors and practice of primary prevention of CVD amongst Nigerian community pharmacists. Read More

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http://link.springer.com/10.1007/s11096-018-0744-3
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http://dx.doi.org/10.1007/s11096-018-0744-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280866PMC
December 2018
10 Reads

Descriptive analysis of pharmacy services provided after community pharmacy screening.

Int J Clin Pharm 2018 Dec 26;40(6):1577-1586. Epub 2018 Nov 26.

McMaster University, 1280 Main St. W., Hamilton, ON, L8S 4L8, Canada.

Background Community pharmacies are promising locations for opportunistic screening due to pharmacist accessibility and ability to perform various health and medication management services. Little is known as to the provision of pharmacy services following screening initiatives. Objective To describe provision of pharmacy services for participants following a community pharmacy stroke screening initiative. Read More

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http://dx.doi.org/10.1007/s11096-018-0742-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280862PMC
December 2018
10 Reads

Survey of outpatients' use and needs of patient medicine information leaflets in Thailand.

Int J Clin Pharm 2019 Feb 16;41(1):141-150. Epub 2018 Nov 16.

Division of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand.

Background Patient information leaflets are important sources of medicine information. Regulations of patient information leaflet provision varies among country. Little is known regarding patients' behavior and expectation on use of patient information leaflets. Read More

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http://dx.doi.org/10.1007/s11096-018-0748-zDOI Listing
February 2019
8 Reads

Medication prescribing errors: a pre- and post-computerized physician order entry retrospective study.

Int J Clin Pharm 2019 Feb 16;41(1):228-236. Epub 2018 Nov 16.

Clinical Pharmacy Department, Toulouse University Hospital Centre, 1 Avenue du Professeur Jean Poulhès, 31059, Toulouse, France.

Background The computerization of prescriptions with a computerized physician order entry contributes to securing the error-free drug supply, but is not risk-free. Objective: To determine the impact of a computerized physician order entry system on prescribing errors immediately after its implementation and 1 year later. Setting The Cardiology and Diabetology Departments at Toulouse University Hospital, France. Read More

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http://link.springer.com/10.1007/s11096-018-0747-0
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http://dx.doi.org/10.1007/s11096-018-0747-0DOI Listing
February 2019
6 Reads

Effectiveness of antibiotic therapy in pediatric patients with cat scratch disease.

Int J Clin Pharm 2018 Dec 16;40(6):1458-1461. Epub 2018 Nov 16.

College of Pharmacy, The Ohio State University, 500 W. 12th Ave, Columbus, OH, 43210, USA.

Background Appropriate antibiotic treatment of cat scratch disease (CSD) in pediatrics is not well established. Objective The purpose of this study was to evaluate the response rates of antibiotic therapy in pediatrics with CSD. Methods The electronic medical records of a cohort of pediatric patients with confirmed diagnosis of CSD (2006-2016) were reviewed, retrospectively. Read More

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http://dx.doi.org/10.1007/s11096-018-0746-1DOI Listing
December 2018
11 Reads