11,399 results match your criteria International Journal of Biological Macromolecules [Journal]


The first complete mitochondrial genome of a cyclophorid land snail, with implications for architaenioglossan relationships (Mollusca, Caenogastropoda, Cyclophoroidea).

Int J Biol Macromol 2019 Apr 19. Epub 2019 Apr 19.

School of Life Sciences, Nanchang University, Nanchang 330031, China. Electronic address:

Herein, we described the complete mitochondrial genome ('mitogenome') of the Chinese land snail Cyclophorus martensianus, which is the first published mitogenome for the caenogastropod family Cyclophoridae. This mitogenome is 15,308 bp long consisting of 37 genes: 13 protein-coding genes (PCG's), 22 tRNA genes and two rRNA genes. The A + T content (69. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.138DOI Listing
April 2019
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Wound dressing properties of cationized cotton fabric treated with carrageenan/cyclodextrin hydrogel loaded with honey bee propolis extract.

Int J Biol Macromol 2019 Apr 18. Epub 2019 Apr 18.

Pre-Treatment and Finishing of Cellulosic Fabric Department, Textile Research Division, National Research Center, 33 El-Behooth St, Dokki, Giza 12311, Egypt. Electronic address:

The current study was set to prepare a delivery system based on a mixture of biodegradable polymeric hydrogel (i.e., carrageenan (κ-CAR) and β-cyclodextrin (β-CD)) for encapsulating honey bee propolis extract (HBP). Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.065DOI Listing

The synthesis and characterization of zinc-containing electrospun chitosan/gelatin derivatives with antibacterial properties.

Int J Biol Macromol 2019 Apr 18. Epub 2019 Apr 18.

Pretreatment & Finishing of Cellulose Based Textiles Dept., National Research Centre, Scopus Affiliation ID: 60014618, P.O. Box 12622, 33 EL-Bohouth St., Dokki, Giza, Cairo, Egypt. Electronic address:

Homogenous allocation of inorganic particles in a polymeric matrix is a challenge. In this work, we discuss electrospinning of chitosan /gelatin using CS-Si (chitosan silicone hybrids) as well as the formation of homogeneously distributed Zn elements inside chitosan nanofiber through chitosan -GPTMS hybrids. Chitosan -GPTMS hybrids can be synthesized by acid catalyzed amino-oxirane addition reaction. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.047DOI Listing
April 2019
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Probing the binding interaction of zinc and cadmium with garlic phytocystatin: Implication of the abiotic stress on garlic phytocystatin.

Int J Biol Macromol 2019 Apr 18. Epub 2019 Apr 18.

Department of Biochemistry, Aligarh Muslim University, Aligarh 202002, Uttar Pradesh, India. Electronic address:

Abiotic stress induced by heavy metals retards the growth and development of plants. Therefore, it is essential to have an insight into the potential toxic effects of heavy metals. The present article investigates the effect of zinc and cadmium on the structure and function of garlic phytocystatin (GPhyCys). Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.036DOI Listing

Investigating architecture and structure-function relationships in cold shock DNA-binding domain family using structural genomics based approach.

Int J Biol Macromol 2019 Apr 18. Epub 2019 Apr 18.

Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India. Electronic address:

Oligonucleotide/oligosaccharide-binding fold (OB-fold) plays a major role in the regulation of central dogma of life via binding though DNA and RNA. The OB-fold domains are diverse in nature and present in large number of proteins with verities of molecular functions. Here, we have investigated the distribution of sequence, structure and repeats of cold shock DNA-binding proteins (CSDB), a member of OB-fold, in all three kingdoms to establish functional relationships. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.135DOI Listing

Influence of the welan gum biopolymer concentration on the rheological properties, droplet size distribution and physical stability of thyme oil/W emulsions.

Int J Biol Macromol 2019 Apr 18. Epub 2019 Apr 18.

Departamento de Ingeniería Química, Facultad de Química, Universidad de Sevilla, C/ Profesor García González, s/n, 41012 Sevilla, Spain. Electronic address:

The objective of this work is to obtain a stable and natural antimicrobial delivery system. Thus, the effect of the addition of a natural polysaccharide such as welan gum on the linear viscoelastic properties, flow behaviour, droplet size distribution and physical stability of thyme oil/W emulsions formulated with a wheat-derived surfactant was studied. All emulsions obtained show submicron diameters regardless of the concentration of welan. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.137DOI Listing

Characterization of a high-performance edible film based on Salep mucilage functionalized with pennyroyal (Mentha pulegium).

Int J Biol Macromol 2019 Apr 18. Epub 2019 Apr 18.

Transfer Phenomena Laboratory (TPL), Department of Food Science, Technology and Engineering, Faculty of Agricultural Engineering and Technology, University of Tehran, Iran.

Salep mucilage was extracted from salep tubers and used to produce edible films containing pennyroyal extracts (PER) (0, 0.5, 1, and 1.5% v/v) as a new antibacterial/antioxidant edible film, and their physical, mechanical, permeability, thermal, microstructural and antibacterial properties were measured. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.136DOI Listing
April 2019
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Development of a nanocomposite scaffold of gelatin-alginate-graphene oxide for bone tissue engineering.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Department of Polymer and Process Engineering, Indian Institute of Technology Roorkee, Roorkee, India. Electronic address:

Bone damage, due to congenital defects, trauma and sports-related injuries, has become a foremost health problem all over the world. The present study involves fabrication of a nanocomposite scaffold of graphene oxide (GO), gelatin and alginate, with an aim of enhancing bone regeneration. The effect of varying concentration of GO on the scaffold properties was also determined. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.113DOI Listing

Effect of temperature in Chitin and Chitosan production by solid culture of Penicillium Camembertii on YPG medium.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Univ Rennes, Ecole Nationale Supérieure de Chimie de Rennes, CNRS, UMR 6226, F-35000 Rennes, France.

This study was devoted to polysaccharides extraction (Chitin and Chitosan) from Penicillium camembertii cell wall. A culture on solid medium was adopted under carefully selected conditions, appropriate to mycelium growth: duration 6 days, medium YPGA and pH 5. The temperature was adjusted (20 °C to 28 °C) in order to study the effect of temperature on Chitin/Chitosan production. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.116DOI Listing
April 2019
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Bio-assay: The best alternative for conventional methods in detection of epidermal growth factor.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Nanotechnology Research Center, Uremia University, Uremia, Iran.

Growth factors are necessary for proper and efficient wound closure and tissue regeneration. Epidermal growth factor (EGF) is one of the key signaling molecules in stimulating epithelial cell motility, making it a required factor for re-epithelialization. Increased EGF expression is likely to be a strong prognostic and predictive feature in multiple tumor types and determination of EGF may product remarkable diagnosis benefits. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.121DOI Listing
April 2019
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Amination of ficin extract to improve its immobilization on glyoxyl-agarose: Improved stability and activity versus casein.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Departamento de Biocatálisis, Instituto de Catálisis-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain. Electronic address:

Ficin extract has been aminated using ethylenediamine and carbodiimide to transform all exposed carboxylic groups into amino groups, retaining around 80% of activity versus benzoyl-d,l-arginine p-nitroanilide hydrochloride (BANA) and 90% versus casein. This aminated enzyme was then immobilized on glyoxyl agarose beads. After optimization of the immobilization protocol (immobilization at pH 10 for just 1 h), the new biocatalyst was compared to that obtained using the non-aminated enzyme. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.123DOI Listing

Isolation and structural characterization of a levan produced by probiotic Bacillus tequilensis-GM from Tunisian fermented goat milk.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Department of Chemical Sciences, University of Naples "Federico II", Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy.

The probiotic features of strain GM newly isolated from Tunisian spontaneously fermented goat milk and identified as Bacillus tequilensis-GM were assessed. Strain GM showed high resistance to saliva (90.64%), gastric juice (88. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.130DOI Listing
April 2019
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Tragacanth gum based hydrogel nanocomposites for the adsorption of methylene blue: Comparison of linear and non-linear forms of different adsorption isotherm and kinetics models.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Chemistry group, Pardis College, Isfahan University of Technology, Isfahan 84156-83111, Islamic Republic of Iran.

In the current work, novel eco-friendly hydrogel nanocomposite biosorbents (ef-HNCs) made up from tragacanth gum and modified CaCO nanoparticles (CC NPs) were applied for the adsorption of methylene blue dye (MBD). A simple, fast, and safe method regarding green chemistry was used to prepare the ef-HNC, with the aid of ultrasound waves. The ef-HNCs were successfully characterized using several spectroscopic, microscopic, and analytical methods. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.129DOI Listing
April 2019
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An optimized cocktail of chitinolytic enzymes to produce N,N'-diacetylchitobiose and N-acetyl-d-glucosamine from defatted krill by-products.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

State Key Laboratory of Fine Chemical Engineering and School of Life Science and Biotechnology, Dalian University of Technology, Dalian 116024, China; Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China. Electronic address:

Defatted krill powder (DKP), the byproduct of krill oil industry, is a resource of biological macromolecules. Here, one bacterial protease, three bacterial chitinases and one insect N-acetyl-d-hexosaminidase were integratively used to produce peptide, N,N'-diacetylchitobiose [(GlcNAc)] and N-acetyl-d-glucosamine (GlcNAc) from DKP. First, alkaline protease was found to outperform neutral protease in deproteinizing DKP and the resultant krill peptides were rich in essential amino acids (41. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.114DOI Listing
April 2019
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Physicochemical properties of partially α-glucan-coated normal corn starch formed by amylosucrase from Neisseria polysaccharea.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Department of Food Science & Biotechnology, Gachon University, Seongnam 13120, Republic of Korea. Electronic address:

Amylosucrase (AS) is a glycosyltransferase that produces linear α-1,4 glucans using sucrose as the sole substrate. In this study, for various applications, α-glucan-coated starch (α-GCS) was produced by AS (20 U/L) from Neisseria polysaccharea to improve the physicochemical properties of raw normal corn starch (NCS) by applying different reaction conditions (i.e. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.133DOI Listing

Investigating the formulation of alginate- gelatin encapsulated Pseudomonas fluorescens (VUPF5 and T17-4 strains) for controlling Fusarium solani on potato.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Department of Plant Protection, Faculty of Agriculture, Vali-e-Asr University of Rafsanjan, Iran.

Nanotechnology is one of the most fascinating sciences with a great potential to improve many agricultural products. Use of nanoparticles in plant disease management is a novel area which may prove very effective in future. Use of nanomaterials and biocompatible compounds in nano-encapsulation of antagonist bacteria is an important step in enhancing the efficiency of these agents in adverse environmental conditions. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.071DOI Listing

A novel peroxidase from Arabian balsam (Commiphora gileadensis) stems: Its purification, characterization and immobilization on a carboxymethylcellulose/FeO magnetic hybrid material.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Department of Chemistry, University College in Al-Jamoum, Umm Al-Qura University, Makkah, Saudi Arabia.

A novel plant peroxidase was isolated from the stem of Arabian balsam (Commiphora gileadensis) and purified using ammonium sulfate, followed by ion exchange chromatography (DEAE-Sepharose) and gel filtration (Sephacryl S-200). The newly isolated peroxidase was characterized as having a specific activity of 9503.3 unit/mg of protein after 20. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.119DOI Listing
April 2019
2.858 Impact Factor

A novel polysaccharide from Dendrobium devonianum serves as a TLR4 agonist for activating macrophages.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

School of Basic Medical Sciences & Forensic Medicine, Hangzhou Medical College, Hangzhou 310053, China. Electronic address:

Dendrobium devonianum has been used as herbal medicines and nutraceutical products since ancient time in China. However, its chemical composition and pharmacological mechanisms are not fully known. In present studies, by chemical purification and characteristic identification, we discovered a novel polysaccharide from D. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.125DOI Listing
April 2019
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Monosaccharide composition influence and immunomodulatory effects of probiotic exopolysaccharides.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Department of Food Science and Nutrition, Meiho University, Taiwan. Electronic address:

Exopolysaccharides (EPSs) are metabolites of probiotics that have gained wide interest recently. A strain of Lactobacillus reuteri Mh-001 with high exopolysaccharide (EPS) production ability was isolated, identified, and were used to investigate the anti-inflammatory effects of the EPSs. Among the three unpurified EPSs, RAW246. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.109DOI Listing

Regulation of neuronal microtubule dynamics by tau: Implications for tauopathies.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, India. Electronic address:

In specialized cell types such as neurons, microtubules maintain the integrity of axons by forming stable bundles and facilitate the transport of synaptic vesicles. The cells regulate the stability and dynamics of microtubules using a diverse array of mechanisms. One of the mechanisms involves the interaction of microtubules with its associated proteins. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.120DOI Listing
April 2019
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Improved emulsion stability and resveratrol encapsulation by whey protein/gum arabic interaction at oil-water interface.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Department of Food Technology, ATEI of Thessaloniki, 57400 Thessaloniki, Greece.

This work studied the effects of different concentrations of gum arabic (GA) on the interfacial adsorption kinetics of whey protein (WP) at the oil-water interface, the possibility of emulsion stabilized by WP/GA mixtures, and use of such emulsions as resveratrol delivery systems. Dynamic interface pressure measurements indicated that the change of GA concentration significantly affected the diffusion, penetration and rearrangement of WP at the oil-water interface, while measurements of hydrodynamic diameter and ζ-potential indicated electrostatic and hydrophobic interactions between WP and GA. The rheological measurements of the emulsions supported the above observations and indicated that different GA concentrations affected the viscoelastic properties of the emulsion. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.126DOI Listing
April 2019
2 Reads

Synthesis and characterization of porous tree gum grafted copolymer derived from Prunus cerasifera gum polysaccharide.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Integrated Composites Laboratory (ICL), Department of Chemical & Biomolecular Engineering, University of Tennessee, Knoxville, TN 37996, USA. Electronic address:

Porous grafted copolymer with excellent thermal stability and swelling capacity was synthesized from water soluble Prunus cerasifera gum polysaccharide (PG) and acrylamide (AM). The monosaccharide compositions and the structure of Prunus cerasifera tree gum were detected by a high-performance anion exchange chromatography (HPAEC) system and H NMR and C NMR, and the obtained PG-AM copolymer was characterized by Fourier transform infrared (FT-IR), scanning electron microscope (SEM), thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC), respectively. The results indicated that the water soluble polysaccharides obtained from Prunus cerasifera tree gum were mainly composed of l-arabinose (39. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.128DOI Listing

Assessment of silver nanoparticles decorated starch and commercial zinc nanoparticles with respect to their genotoxicity on onion.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Pre-Treatment and Finishing of Cellulosic Fabric Department, Textile Research Division, National Research Centre, 33 El-Behooth St, Dokki, Giza 12311, Egypt. Electronic address:

High throughput production of silver nanoparticles (AgNPs) having controlled size appropriate for industrial purposes were achieved via using facile and ecofriendly chemical reduction method. Native rice starch was used as reductant for silver ions (Ag) to silver atoms (Ag), as well as stabilizing for the obtainable AgNPs. Two different concentrations; 2000 ppm and 4000 ppm were successfully prepared and coded as AgNPs-2000 and AgNPs-4000 respectively. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.134DOI Listing
April 2019
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Hyaluronic acid - dihydroartemisinin conjugate: Synthesis, characterization and in vitro evaluation in lung cancer cells.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Product Development Cell-II, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India. Electronic address:

In recent years, a great deal of attention has been given towards re-purposing and re-innovating the potential drugs. In this regard, dihydroartemisinin (DHA) has been reported to demonstrate anti-proliferative effects on various cancerous cells viz. breast, liver and lung. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.124DOI Listing
April 2019
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Structure and distribution changes of Eucalyptus hemicelluloses during hydrothermal and alkaline pretreatments.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Center for Lignocellulose Science and Engineering, Liaoning Key Laboratory Pulp and Paper Engineering, Dalian Polytechnic University, Dalian 116034, China.

Eucalyptus wood was pretreated with an integrated process based on hydrothermal and alkaline pretreatments. The structural changes of hemicelluloses during the pretreatments and the components of the hydrolysates were comprehensively characterized. Sugar and spectral analyses indicated that the hemicelluloses remained in the residues obtained at hydrothermal pretreatment under low temperatures were mainly composed of a (1 → 4)-β-D-Xylp backbone with 4-O-methyl-α-D-glucuronic acids attached at O-2 of the xylose together with various monosaccharides of rhamnose, arabinose, galactose, glucose, and mannose. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.127DOI Listing

Composite edible coatings from commercial pectin, corn flour and beetroot powder minimize post-harvest decay, reduces ripening and improves sensory liking of tomatoes.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Center of Innovative and Applied Bioprocessing (CIAB), Sector-81 (Knowledge City), Mohali 140306, Punjab, India. Electronic address:

The present study aimed to enhance the shelf life of tomatoes at pink-red stage through pectin (P), corn flour (CF) and beetroot powder (B) based coatings. PCF11 coating was resulted in significant enhancement of shelf life and quality retention of tomato in terms of physiological weight loss (PWL), decay per cent, ripening index, respiration rate, hue angle, firmness and DPPH antioxidant activity. Lower amounts of glucose and fructose quantified through HPLC indicated lesser cell wall components degradation in tomatoes coated with P and PCF11. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.132DOI Listing
April 2019
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Systematic optimization of cationic surface engineered mucoadhesive vesicles employing Design of Experiment (DoE): A preclinical investigation.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Pharmaceutics Research Projects Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour Central University, Sagar, M.P. 470 003, India. Electronic address:

Fungal keratitis (FK) is treated by topical natamycin (Nat) which is an effective antifungal agent. However, it has numerous therapeutic limitations i.e. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.118DOI Listing
April 2019
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Polysaccharide and polypeptide based injectable thermo-sensitive hydrogels for local biomedical applications.

Int J Biol Macromol 2019 Apr 17. Epub 2019 Apr 17.

Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei 106, Taiwan; Advanced Membrane Materials Research Center, National Taiwan University of Science and Technology, Taipei 106, Taiwan; R&D Center for Membrane Technology, Chung Yuan Christian University, Chungli, Taoyuan 320, Taiwan.

Injectable thermo-responsive hydrogels have been studied for various biomedical applications including; drug delivery, cell encapsulation, and tissue repairing. There are various natural and synthetic polymers which exhibit homogenous injectable solution at ambient temperature and form a gel in human body temperature. Polysaccharide, polypeptide and other biological macromolecule based hydrogels have been getting immense attention in biomedical application due to their low immunogenicity, abundance in nature, high biocompatibility and biodegradability. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.131DOI Listing
April 2019
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Anti-inflammatory effects of vanadium-binding protein from Halocynthia roretzi in LPS-stimulated RAW264.7 macrophages through NF-κB and MAPK pathways.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Department of Food Science and Biotechnology, Kyung Hee University, Yongin 17104, Republic of Korea; Skin Biotechnology Center, Kyung Hee University, Suwon 16229, Republic of Korea. Electronic address:

Vanadium-binding protein (VBP) was separated from the blood of the fresh sea urchin Halocynthia roretzi through (NH)SO precipitation, Diethylaminoethyl Sepharose fast-flow ion-exchange chromatography, and Sephacryl S-200 high-resolution size-exclusion chromatography. The protein size and purification yield of VBP were 27 kDa and 5.5%, respectively. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.106DOI Listing

Comparative study of keratin extraction from human hair.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Department of Materials Engineering, Indian Institute of Science, Bangalore, Karnataka 560012, India. Electronic address:

Keratin has been attracting interest due to its stability against enzymatic degradation thereby allowing more predictable degradation profile for tissue regeneration. While the efficacy of keratin has been demonstrated in different tissue models, there has been no systematic study to investigate and compare the different routes of keratin extraction from human hair. Here, we compared the four commonly used extraction methods and highlight the both physical and chemical differences in the extracted keratin. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.098DOI Listing
April 2019
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Design and evaluation of chitosan/chondroitin sulfate/nano-bioglass based composite scaffold for bone tissue engineering.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

School of Biochemical Engineering, Indian Institute of Technology, Banaras Hindu University, Varanasi 221005, India. Electronic address:

Chitosan, a natural biopolymer with osteoconductive properties is widely investigated to generate scaffolds for bone tissue engineering applications. However, chitosan based scaffolds lacks in mechanical strength and structural stability in hydrated condition and thereby limits its application for bone tissue regeneration. Thus in the present study, to overcome the limitations associated with chitosan based scaffolds, we fabricated polyelectrolyte complexation mediated composite scaffold of chitosan and chondroitin sulfate incorporated with nano-sized bioglass. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.107DOI Listing
April 2019
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Chitosan and gelatin-based electrospun fibers for bone tissue engineering.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu, India. Electronic address:

Fractures and injuries pertaining to bone tissue usually take prolonged periods for its natural healing. To overcome this problem, the field of bone tissue engineering (BTE) has acquired an efficient designing mechanism that incorporates cells, biomaterials and the corresponding growth factors to promote both osteogenesis as well as mineralization of the bone. Amidst the various techniques available for scaffold creation, electrospinning is considered superior as it paves the way for the creation of nanostructured scaffolds using biopolymers. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.115DOI Listing
April 2019
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Genetic variation in starch physicochemical properties of Chinese foxtail millet (Setaria italica Beauv.).

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Department of Food Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China. Electronic address:

In this study, 34 Chinese foxtail millet germplasm accessions (cultivars and breeding lines) were characterized for starch physicochemical properties including apparent amylose content, and gel textural, RVA pasting, thermal and retrogradation properties. The relationships among 21 starch parameters were discussed based on correlation analysis and hierarchical cluster analysis. Generally, this set of germplasm presented a surprisingly low genetic diversity in starch properties. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.022DOI Listing
April 2019
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Comparative transcriptome analyses reveal changes of gene expression in fresh and cryopreserved yellow catfish (Pelteobagrus fulvidraco) sperm and the effects of Cryoprotectant MeSO.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China. Electronic address:

This study, for the first time in fish, compared the transcriptome of fresh and frozen-thawed sperm, and would help to better understand the effect of cryopreservation on fish sperm and then better preserve the aquatic germplasm resources. Here, we employed high-throughput sequencing technology to obtain the transcriptome of yellow catfish from fresh sperm, cryopreserved sperm with and without cryoprotectant. When cryoprotectant (MeSO) was excluded, down-regulated genes were significantly enriched into calcium ion binding, cytoskeletal protein binding, microfilament motor activity and carnitine O-acyltransferase activity, which affected Ca regulation, cellular morphology, motility and metabolism. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.050DOI Listing
April 2019
2 Reads

Water extractable pentosans - Quantification of ferulic acid using RP-HPLC, techno-rheological and antioxidant properties.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Department of Food Science and Technology, University of Kashmir, Srinagar 190006, India.

Water extractable pentosans extracted from three varieties of oats were studied for structural analysis using ATR- FTIR, ferulic acid content using RP-HPLC, antioxidant activity by DPPH, reducing power, and metal chelating assays, and functional properties. The appearance of absorption band at 1720 cm in water extractable pentosans is assigned to the presence of aromatic esters as displayed from ATR-FTIR spectrum. All the samples exhibited non-newtonian behavior with viscosities following the order; SWEP > 20WEP > 90WEP. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.112DOI Listing
April 2019
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Use of gelatin and gum arabic for microencapsulation of probiotic cells from Lactobacillus plantarum by a dual process combining double emulsification followed by complex coacervation.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Food Technology Department, Federal University of Viçosa (UFV), P.H. Rolfs Avenue, Campus, 36570-900 Viçosa, MG, Brazil.

The objectives of this study were i) to microencapsulate probiotic cells of Lactobacillus plantarum through a dual process consisting of emulsification followed by complex coacervation using gelatin and gum arabic, ii) to characterize the lyophilized microcapsules, iii) to evaluate their behavior in simulated in vitro gastrointestinal conditions and iv) to evaluate the survival of microencapsulated probiotic cells during 45 days of storage at 8 °C, 25 °C and -18 °C. The optimized conditions for complex coacervation consisted of a 50:50 biopolymer ratio and pH = 4.0. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.110DOI Listing

Correct partner makes the difference: Septin G-interface plays a critical role in amyloid formation.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Instituto de Física de São Carlos, Universidade de São Paulo, Av. João Dagnone, 1100, São Carlos, SP CEP 13563-120, Brazil. Electronic address:

Septins are members of a group of GTP-binding proteins highly conserved in eukaryotes, being linked to diverse cell processes, such as cytokinesis and membrane association. On the other hand, the malfunction of septins is linked to several pathological processes including neurodegeneration and oncogenesis. Septins interact with each other forming heterocomplexes that polymerize in filaments. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.105DOI Listing

Nanocrystalline cellulose: Preparation, physicochemical properties, and applications in drug delivery systems.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address:

Cancer is the leading cause of death all over the world and chemotherapy is an important approach to fight cancer, however, there are many obstacles against successful cancer chemotherapy such as development of multidrug resistance, poor solubility of chemotherapeutic agents and adverse side effects to healthy tissues. An important strategy to overcome these obstacles, is the use of nanotechnology. In recent years, natural polymers such as cellulose and its nanoform structure, nanocrystalline cellulose (NCC), have attracted the interest of researchers in the field of nanotechnology and specially drug delivery systems, due to biocompatibility and biodegradability of NCC. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01418130193169
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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.117DOI Listing
April 2019
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Identification of the anchoring protein SpoIIIJ for construction of the microbial cell surface display system in Bacillus spp.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address:

Microbial cell surface display technology is a powerful tool for displaying proteins on the surfaces of cells. However, few anchoring proteins can be employed for the display of target proteins on the cell surface of the environmentally benign Gram-positive bacterium Bacillus subtilis. In this study, bioinformatics tools were used to screen all of the encoded proteins of B. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01418130193048
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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.033DOI Listing
April 2019
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Presence of actin binding motif in VgrG-1 toxin of Vibrio cholerae reveals the molecular mechanism of actin cross-linking.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur 741246, Nadia, West Bengal, India. Electronic address:

Type VI secretion systems (T6SS) plays a crucial role in Vibrio cholerae mediated pathogenicity. Tip of T6SS is homologous to gp27/gp5 complex or tail spike of T4 bacteriophage. VgrG-1 of V. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.026DOI Listing
April 2019
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Molecular, crystal and physicochemical properties of granular waxy corn starch after repeated freeze-thaw cycles at different freezing temperatures.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

College of Food Science and Engineering, Northwest A&F University, Yangling 712100, China. Electronic address:

The study was undertaken to reveal the effects of freeze-thaw cycles at different freeze temperature (-20 °C, -40 °C and -80 °C) and the number of freeze-thaw cycles (3, 6, 12, 18, 24 times) on physicochemical and structural properties of waxy corn starch. The number of pores on the surface of starch granules increased, but there was no significant (P < 0.05) effect on molecular weight, transparency, freeze-thaw stability and the crystal structure of starch after repeated freeze-thaw cycle. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.111DOI Listing

Antibacterial free-standing polysaccharide composite films inspired by the sea.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, 4805-017 Barco, Guimarães, Portugal; ICVS/3B's PT Associate Laboratory, Guimarães, Portugal. Electronic address:

The adhesive capabilities of marine mussel proteins are well-known, exhibiting the ability to stick to different underwater substrates, either inorganic or organic. These unique adhesive properties are due to the high levels of amino acid, 3,4-dihydroxyphenyl-l-alanine (DOPA), which presents the reactive catechol group. Herein, novel antibacterial free-standing (FS) films were developed with natural polymers, namely chitosan (CHT) and hyaluronic acid (HA), being the catechol-functionalized hyaluronic acid (HA-DN) also included to provide wet adhesive properties. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01418130193042
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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.102DOI Listing
April 2019
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Rheological properties of Prunus persica exudate: Potential effects of proteins and polyphenols.

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Shanghai Engineering Research Center of Food Microbiology, School of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. Electronic address:

This study was to investigate the rheological properties of graded Prunus persica exudates (peach gums). Graded peach gums were extracted by hot water and precipitated by ethanol to obtain white peach gum polysaccharide (WPGP) and yellow peach gum polysaccharide (YPGP). Chemical analysis showed that YPGP had 0. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.104DOI Listing
April 2019
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Protective effects of Ulva pertusa polysaccharide and polysaccharide‑iron (III) complex on cyclophosphamide induced immunosuppression in mice.

Int J Biol Macromol 2019 Apr 15. Epub 2019 Apr 15.

Institute of Extreme Environment Nutrition and Protection, Harbin Institute of Technology, Harbin, China; National Local Joint Laboratory of Extreme Environmental Nutritional Molecule Synthesis Transformation and Separation, Harbin, China. Electronic address:

A water-soluble polysaccharide was isolated from marine green algae Ulva pertusa and then chelated with iron to prepare the polysaccharide‑iron (III) complex. The immunomodulatory activities of sulfated polysaccharide and polysaccharide‑iron (III) complex were investigated through a mice immune-deficiency model. Cyclophosphamide (Cy) was utilized to establish mice immunodeficiency model. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.101DOI Listing

Quercetin binding to Spatholobus parviflorus lectin: Promise of a macromolecular, specific-compound carrier for drug.

Int J Biol Macromol 2019 Apr 13. Epub 2019 Apr 13.

School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam, Kerala 686560, India. Electronic address:

Glycan recognition is the most attractive defining feature of lectins, and also they exhibit specific phytochemical interactions at distinct sites without interfering the glycocode recognition capability. These additional sites may be viewed as potential drug carrying sites that could be exploited for targeted drug delivery. The pharmacological effects of quercetin (QN) have already been studied. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.100DOI Listing
April 2019
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Identification and characterization of a polysaccharide from the roots of Morinda officinalis, as an inducer of bone formation by up-regulation of target gene expression.

Int J Biol Macromol 2019 Apr 13. Epub 2019 Apr 13.

School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China. Electronic address:

Morinda officinalis is an important traditional tonic herbal medicine. In the present study, we found that crude polysaccharides extracted from M. officinalis, named MO90, could significantly increase the bone mineral density (BMD) of the whole femur, distal femur, and proximal femur in ovariectomized (OVX) rats. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.084DOI Listing
April 2019
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Heat shock protein 70 of filarial parasite Setaria equina: Cloning, expression, and analysis of binding with diethylcarbamazine citrate.

Int J Biol Macromol 2019 Apr 13;133:202-213. Epub 2019 Apr 13.

Immunity Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.

Setaria equina heat shock protein (SeqHSP) 70 gene was characterized, cloned and expressed to recombinant protein (rSeqHSP70). The protein was tested for binding with an anti-filarial drug "diethylcarbamazine citrate (DEC)" by equilibrium dialysis method. Molecular docking was also used to determine the binding sites and residues of binding with DEC. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.053DOI Listing
April 2019
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High-value utilization of kraft lignin: Color reduction and evaluation as sunscreen ingredient.

Int J Biol Macromol 2019 Apr 13;133:86-92. Epub 2019 Apr 13.

State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou 510640, Guangdong, China; Ministry of Education Key Laboratory of Pollution Control and Ecological Remediation for Industrial Agglomeration Area, College of Environment and Energy, South China University of Technology, Guangzhou 510006, China.

Dark color of lignin puts brakes on its development as sunscreen ingredient. In order to address this issue, the color of lignin was whitened by facile and economical approach via solvent fractionation and follow-up acetylation. After the two-step treatment, the color of lignin was highly lightened by 313. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01418130193174
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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.092DOI Listing
April 2019
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Preparation of chitosan-Cu/NH physical hydrogel and its properties.

Int J Biol Macromol 2019 Apr 13;133:67-75. Epub 2019 Apr 13.

School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, PR China.

Chitosan (CTS) physical hydrogels crosslinked under gaseous ammonia atmospheres have attracted considerable attentions for their abilities to maximize the biological activities of CTS while maintaining their biocompatibility. However, poor mechanical properties significantly limit their application. The CTS-metal ion complexing hydrogels showed better mechanical properties. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.03.011DOI Listing
April 2019
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Comparative preservation effect of water-soluble and insoluble chitosan from Tenebrio molitor waste.

Int J Biol Macromol 2019 Apr 13;133:165-171. Epub 2019 Apr 13.

Chongqing Engineering Research Center for Processing & Storage of Distinct Agricultural Products, Chongqing Technology and Business University, Chongqing 400067, China.

Edible films and coatings have been developed based on numerous natural biopolymers, which have been used to increase fresh-cut fruit shelf life. Here, we present the preparation, characteristics and preservation effect of water-soluble chitosan (WSC) and water-insoluble chitosan (WIC) from Tenebrio molitor waste (TMW) on fresh-cut apple slices. WIC was isolated from TMW in four steps and WSC was obtained from the WIC solution by 8% HO treatment at 40 °C for 3 h. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.094DOI Listing