1 results match your criteria International Journal of Analytical Mass Spectrometry and Chromatography

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Formation of Mercury(II)-Glutathione Conjugates Examined Using High Mass Accuracy Mass Spectrometry.

Int J Anal Mass Spectrom Cromatogr 2013 Dec;1(2):90-94

Department of Chemistry, University at Buffalo, State University of New York, Buffalo, USA.

Maternal exposure to Hg(II) during pregnancy has been identified as a potential causal factor in the development of severe neurobehavioral disorders. Children with autism have been identified with lower reduced glutathione (GSH)/oxidized glutathione (GSSG) ratios, and GSH is known to strongly bind Hg(II). In order to gain insight into the mechanism by which GSH binds Hg(II), high resolution mass spectrometry coupled with tandem mass spectrometry was utilized to examine the conjugation process. Read More

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http://dx.doi.org/10.4236/ijamsc.2013.12011DOI Listing
December 2013
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