226 results match your criteria Interdisciplinary Perspectives on Infectious Diseases [Journal]


Daclatasvir and Sofosbuvir Therapy Enhance Monocyte Phenotypic Changes in Naive Chronic Hepatitis C Patients: A Prospective Cohort Study.

Interdiscip Perspect Infect Dis 2019 3;2019:9469567. Epub 2019 Feb 3.

Clinical Pathology Department, Faculty of Medicine for Boys, Al-Azhar University, Assiut, Egypt.

Background: Liver inflammation influences monocyte function, recruitment, and consequently inflammatory and fibrogenic responses. We aimed to investigate changes in the circulating monocyte phenotypes in response to Daclatasvir-Sofosbuvir (SOF/DCV) therapy in chronic hepatitis C (CHC) and relate findings to the viral kinetics and the fibrosis score.

Methods: A longitudinal study involving 100 treatment-naïve patients and 30 healthy controls, tested for liver function, fibrosis scores (AST to platelet ratio index, FIB-4), and blood monocyte subsets based on CD14/CD16 expression by flow cytometer. Read More

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http://dx.doi.org/10.1155/2019/9469567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420991PMC
February 2019

Antibiotic Susceptibility Pattern and Biofilm Formation in Clinical Isolates of spp.

Interdiscip Perspect Infect Dis 2019 3;2019:7854968. Epub 2019 Mar 3.

Department of Microbiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India.

is a commensal in the intestine and is now emerging as a drug-resistant pathogen. It produces different virulence factors. surface protein (esp) is a virulence factor that helps in the adhesion, but its role in biofilm formation is still contradictory. Read More

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http://dx.doi.org/10.1155/2019/7854968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420983PMC

Vaccine Prophylaxis of Pneumococcal Infections in Children under Conditions of Severe Flood in the Amur River Basin.

Interdiscip Perspect Infect Dis 2019 18;2019:5467275. Epub 2019 Feb 18.

The Khabarovsk Research Institute of Epidemiology and Microbiology, Khabarovsk 680610, Russia.

Background: Pneumococcal infection being one of the dominant causes of acute respiratory diseases and exacerbation of chronic ones is a serious problem for human health and society. The flood in the Amur river basin in the summer of 2013 created a special zone and risk conditions for the formation of respiratory pathology in the Far-Eastern region of Russia. We aimed to give clinical and epidemiological assessment of the effectiveness of vaccination programs of respiratory viral and pneumococcal infections and generalization of regional experience in the organization of a set of measures aimed at their prevention in the postflood period in the Far-Eastern region. Read More

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http://dx.doi.org/10.1155/2019/5467275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398015PMC
February 2019
1 Read

Current Practice and Barriers to an Early Antimicrobial Conversion from Intravenous to Oral among Hospitalized Patients at Jimma University Specialized Hospital: Prospective Observational Study.

Interdiscip Perspect Infect Dis 2019 29;2019:7847354. Epub 2019 Jan 29.

Clinical Pharmacist and Lecturer, Department of Pharmacy, College of Public Health and Medical Sciences, Jimma University, Ethiopia.

Objective: The aim of the present study was to explore the current practice and its barriers to an early antimicrobial conversion from intravenous (IV) to oral (PO) therapy among hospitalized patients.

Method: Hospital based prospective observational study was conducted to assess the practice of an early antimicrobial IV to PO conversion and its barriers using medical chart and case-specific physicians' interviews, respectively, from February to September, 2014. Patient charts and medication records were reviewed for appropriateness of IV to PO conversion program every 24hrs using a pretested data collection abstraction format. Read More

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http://dx.doi.org/10.1155/2019/7847354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379851PMC
January 2019

Vaginal Dysplasia and HIV: An African American and Caribbean American Cohort Study.

Interdiscip Perspect Infect Dis 2019 1;2019:6189837. Epub 2019 Jan 1.

Department of Obstetrics and Gynecology, Division of Research and Special Projects Miami, University of Miami Miller School of Medicine, Miami 33101, USA.

Background: Vaginal cancer is a rare disease with poor clinical outcomes and limited therapeutic options. In the United States (US), minority women and older women are disproportionately diagnosed with late-stage vaginal cancer. Sociodemographic characteristics, risk behaviors, and cooccurring conditions are linked to vaginal intraepithelial neoplasia (VaIN). Read More

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http://dx.doi.org/10.1155/2019/6189837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332938PMC
January 2019
4 Reads

Seroprevalence in a High-Risk Population in Greece: A Cross-Sectional Study.

Interdiscip Perspect Infect Dis 2018 25;2018:8751921. Epub 2018 Dec 25.

Laboratory of Epidemiology and Prevention of Hemoglobinopathies, Acute and Chronic Diseases, Department of Nursing, University of Peloponnese, Valioti & Plateon, 23100 Sparta, Laconia, Greece.

Introduction: Brucellosis is a zoonosis with high occupational risk. However, seroprevalence of antibodies among occupational groups is not known, since studies in endemic countries are rare.

Methods: A cross-sectional seroprevalence study was conducted among livestock farmers in an endemic region in Greece. Read More

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http://dx.doi.org/10.1155/2018/8751921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323493PMC
December 2018
1 Read

An Examination of Bacterial Contamination of Models Used in Anatomy Laboratories.

Interdiscip Perspect Infect Dis 2018 19;2018:9201312. Epub 2018 Dec 19.

Microbiology Department, Faculty of Medicine, Bolu Abant Izzet Baysal University, Turkey.

Background: Bacterial, viral, and parasitic transmission is a common issue involving items that are used in crowded places and are touched. In this study, it was aimed to identify the types of bacteria on models used in anatomy laboratories and the types of bacteria that contaminate students' hands.

Methods: Swab samples were taken from 30 models used in the laboratory and from the dominant hands of 94 students prior to and after contact with the models and were examined in the microbiology laboratory. Read More

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http://dx.doi.org/10.1155/2018/9201312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313981PMC
December 2018
2 Reads

Effects of UVC Irradiation on Growth and Apoptosis of and .

Interdiscip Perspect Infect Dis 2018 2;2018:3748594. Epub 2018 Dec 2.

Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

and are important fungal species isolated from immunocompromised patients. Previous studies have demonstrated that these filamentous fungi exist as saprophytes in the soil and showed the highest minimum inhibitory concentration to several drugs. We aimed to examine how UVC affects the and by investigating the role of UVC on growth, induction of apoptosis by ethidium bromide (EB)/acridine orange (AO) staining, and transcriptomic study of caspase recruitment domain family, member 9 (CARD-9) gene. Read More

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http://dx.doi.org/10.1155/2018/3748594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304556PMC
December 2018
1 Read

The Role of Pneumococcal Virulence Factors in Ocular Infectious Diseases.

Interdiscip Perspect Infect Dis 2018 13;2018:2525173. Epub 2018 Nov 13.

Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS 39216, USA.

is a gram-positive, facultatively anaerobic pathogen that can cause severe infections such as pneumonia, meningitis, septicemia, and middle ear infections. It is also one of the top pathogens contributing to bacterial keratitis and conjunctivitis. Though two pneumococcal vaccines exist for the prevention of nonocular diseases, they do little to fully prevent ocular infections. Read More

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https://www.hindawi.com/journals/ipid/2018/2525173/
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http://dx.doi.org/10.1155/2018/2525173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257906PMC
November 2018
12 Reads

Comparative Antiviral Efficacy of Generic Sofosbuvir versus Brand Name Sofosbuvir with Ribavirin for the Treatment of Hepatitis C.

Interdiscip Perspect Infect Dis 2018 1;2018:9124604. Epub 2018 Oct 1.

Department of Hepatology, Institute of Liver Diseases, Hepato Pancreato Biliary Surgery and Transplant, Global Hospitals, Mumbai, India.

Background: Chronic hepatitis C infection is a major cause for liver failure and liver cancer and can be treated with highly effective all oral directly acting antiviral (DAA) drugs. Generic versions of these DAAs are available in India.

Method: This was an open-label, single-center, prospective, nonrandomized observational study for the comparative safety and efficacy of generic versus brand name sofosbuvir with ribavirin therapy for chronic hepatitis C infection (all genotypes). Read More

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https://www.hindawi.com/journals/ipid/2018/9124604/
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http://dx.doi.org/10.1155/2018/9124604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188723PMC
October 2018
28 Reads

Corrigendum to "Association between Virulence Factors and Extended Spectrum Beta-Lactamase Producing Compared to Nonproducing Isolates".

Interdiscip Perspect Infect Dis 2018 8;2018:1023076. Epub 2018 Jan 8.

Microbiology & Immunology Department, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.

[This corrects the article DOI: 10.1155/2017/7279830.]. Read More

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https://www.hindawi.com/journals/ipid/2018/1023076/
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http://dx.doi.org/10.1155/2018/1023076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817306PMC
January 2018
10 Reads

Monthly or Weekly Supplementation with Cholecalciferol 20,000 IU in People Living with HIV: Results from a Nested Cohort Study.

Interdiscip Perspect Infect Dis 2018 2;2018:7502127. Epub 2018 Sep 2.

University Hospital Klinikum rechts der Isar, Department of Medicine II, Technische Universität München, 80675 Munich, Germany.

Background: There is still considerable uncertainty in handling vitamin D deficiency in people living with HIV (PLWH), due to a lack of comparative data and the wide range of recommended daily intake. Nondaily supplementation might be preferred in many PLWH, but recommendation on dosing has not been established. We aimed to compare the efficacy of weekly versus monthly supplementation with cholecalciferol 20,000 IU in a group of PLWH with vitamin D deficiency in Western Europe. Read More

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https://www.hindawi.com/journals/ipid/2018/7502127/
Publisher Site
http://dx.doi.org/10.1155/2018/7502127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139192PMC
September 2018
3 Reads

Assessment of Knowledge, Attitude, and Practice toward Antibiotic Use among Harar City and Its Surrounding Community, Eastern Ethiopia.

Interdiscip Perspect Infect Dis 2018 8;2018:8492740. Epub 2018 Aug 8.

Department of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.

Purpose: Community plays significant role in the process of emergence and spread of antibiotic resistance. The aim of this study is to assess knowledge, attitude, and practice toward antibiotic use among Harar city and its surrounding community, Eastern Ethiopia.

Patient And Methods: A cross-sectional study was conducted among 384 subjects from February 1 to May 1, 2017, through interview using pretested structured questionnaires. Read More

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http://dx.doi.org/10.1155/2018/8492740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106796PMC
August 2018
3 Reads

Evaluation of Adverse Drug Reaction Profile of Drugs Used as First-Line Antiretroviral Therapy.

Interdiscip Perspect Infect Dis 2018 2;2018:8095609. Epub 2018 Aug 2.

Medical Affairs, Mylan, Bengaluru, India.

Background And Objectives: The objective was to study the adverse drug reaction (ADR) profile in HIV patients receiving first-line antiretroviral therapy.

Methods: This was a prospective, observational study that included 171 HIV patients with a follow-up at six months. Demographic details, medical history, details of HIV infection including most recent CD4 count, details of antiretroviral therapy, and other concomitant medication were recorded. Read More

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http://dx.doi.org/10.1155/2018/8095609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098889PMC
August 2018
6 Reads

Predictors of Mortality in Scrub Typhus Infection Requiring Intensive Care Admission in Tertiary Healthcare Centre of Nepal.

Interdiscip Perspect Infect Dis 2018 3;2018:4867958. Epub 2018 Jun 3.

Faculty of Science, University of Sydney, Sydney, NSW, Australia.

Introduction: This study aimed to explore the predictors of mortality from scrub typhus infection in patients requiring intensive care unit (ICU) admission.

Materials And Methods: A retrospective study was conducted on 120 patients with serum ELISA IgM positive for scrub typhus (optical density ≥ 0.5) admitted at the medical ICU of Chitwan Medical College Teaching Hospital between April 2016 and September 2017. Read More

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http://dx.doi.org/10.1155/2018/4867958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008690PMC
June 2018
11 Reads

Transmission Dynamics of Bovine Anaplasmosis in a Cattle Herd.

Interdiscip Perspect Infect Dis 2018 2;2018:4373981. Epub 2018 May 2.

Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS, USA.

Bovine anaplasmosis is an infectious disease of cattle caused by the obligate intercellular bacterium, , and it primarily occurs in tropical and subtropical regions of the world. In this study, an age-structured deterministic model for the transmission dynamics of bovine anaplasmosis was developed; the model incorporates symptomatic and asymptomatic cattle classes. Sensitivity analysis was carried out to determine the parameters with the highest impact on the reproduction number. Read More

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http://dx.doi.org/10.1155/2018/4373981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954946PMC
May 2018
14 Reads

in Blood Donors: A Study in Boyer-Ahmad County, Southwest Iran.

Interdiscip Perspect Infect Dis 2018 15;2018:3813612. Epub 2018 Apr 15.

Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Iranian Blood Transfusion Organization (IBTO), Tehran, Iran.

is an important foodborne protozoan that can be transmitted through infected blood containing tachyzoite form of the parasite. The current study aimed to evaluate the prevalence of infection and related risk factors among healthy blood donors in Boyer-Ahmad County, southwest Iran. Blood samples were taken from 285 healthy blood donors who voluntarily agreed to participate in this study. Read More

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http://dx.doi.org/10.1155/2018/3813612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925030PMC
April 2018
5 Reads

Influence of Handprint Culture Training on Compliance of Healthcare Workers with Hand Hygiene.

Interdiscip Perspect Infect Dis 2018 5;2018:3727521. Epub 2018 Mar 5.

Department of Pediatrics, Kasr Alainy School of Medicine, Cairo University, Cairo, Egypt.

Objective: We aimed to study the effect of visual observation of bacterial growth from handprints on healthcare workers' (HCWs) compliance with hand hygiene (HH).

Settings: Medical and postoperative cardiac surgery units.

Design: Prospective cohort study. Read More

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http://dx.doi.org/10.1155/2018/3727521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863290PMC
March 2018
8 Reads

Retrospective Assessment of Antibiotics Prescribing at Public Primary Healthcare Facilities in Addis Ababa, Ethiopia.

Interdiscip Perspect Infect Dis 2018 28;2018:4323769. Epub 2018 Feb 28.

Addis Continental Institute of Public Health, P.O. Box 26751/1000, Addis Ababa, Ethiopia.

Antibiotic overprescribing is the major driving force for the emergence of antibiotics resistance. The aim of this study was to assess antibiotics prescribing at primary healthcare facilities in Addis Ababa, Ethiopia. The study was conducted in six public health centers found in Addis Ababa City. Read More

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http://dx.doi.org/10.1155/2018/4323769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851026PMC
February 2018
3 Reads

Prevalence and Associated Symptoms of Infection among Schoolchildren in Kassala State, East of Sudan.

Interdiscip Perspect Infect Dis 2018 15;2018:4325752. Epub 2018 Jan 15.

Department of Clinical Microbiology and Parasitology, College of Medicine, University of Bisha, Bisha, Saudi Arabia.

This study aimed to determine the prevalence of infections among schoolchildren and investigate the associations between seropositivity and existence of gastrointestinal symptoms. . A prospective cross-sectional study was conducted during a period from January to December 2012 at Kassala state, east of Sudan. Read More

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http://dx.doi.org/10.1155/2018/4325752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820545PMC
January 2018
8 Reads

Early Human Migrations (ca. 13,000 Years Ago) or Postcontact Europeans for the Earliest Spread of and to the Americas.

Authors:
Samuel Mark

Interdiscip Perspect Infect Dis 2017 9;2017:6491606. Epub 2017 Nov 9.

Department of Liberal Studies, Texas A&M University at Galveston, P.O. Box 1675, Galveston, TX 77553-1675, USA.

For over a century, it has been widely accepted that leprosy did not exist in the Americas before the arrival of Europeans. This proposition was based on a combination of historical, paleopathological, and representational studies. Further support came from molecular studies in 2005 and 2009 that four single-nucleotide polymorphisms (SNPs) and then 16 SNP subtypes correlated with general geographic regions, suggesting the subtypes in the Americas were consistent with European strains. Read More

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http://dx.doi.org/10.1155/2017/6491606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700473PMC
November 2017
4 Reads

Families Living with Blood-Borne Viruses: The Case for Extending the Concept of "Serodiscordance".

Interdiscip Perspect Infect Dis 2017 18;2017:4352783. Epub 2017 Oct 18.

Social Policy Research Centre, Goodsell Building, Level 3, UNSW, Sydney, NSW 2052, Australia.

The concept of "serodiscordance" (mixed infection status) is primarily associated with epidemiological concerns about HIV transmission risk in couples. We make the case for extending this concept to include families with mixed HIV and viral hepatitis status. Social research on couples with mixed HIV and hepatitis C status has laid an important foundation for illuminating how experiences of serodiscordance within intimate partnerships are much broader than concerns about risk. Read More

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http://dx.doi.org/10.1155/2017/4352783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688372PMC
October 2017
5 Reads

Serum Ferritin: A Backstage Weapon in Diagnosis of Dengue Fever.

Interdiscip Perspect Infect Dis 2017 2;2017:7463489. Epub 2017 Oct 2.

Medical Services, Biocon Limited, Bengaluru 560100, India.

Aims: This retrospective study evaluates ferritin as a surrogate marker for dengue infection (NS1 and IgM negative stage) as opposed to other febrile illnesses of infective or inflammatory etiology (OFI).

Methodology: Data of all patients admitted to medical ward and medical ITU during the dengue outbreak were collected. Patients admitted between 5 and 10 days of febrile illness without a diagnosis were included. Read More

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http://dx.doi.org/10.1155/2017/7463489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643150PMC
October 2017
4 Reads

Local Diversity and Biting Pattern of Species in Southern Minahasa.

Interdiscip Perspect Infect Dis 2017 6;2017:6313016. Epub 2017 Aug 6.

Biomedicine Postgraduate Program, Udayana University, Bali, Indonesia.

Background: To optimize the preventive measures of malaria, it is important to synchronize the efforts with the behavior of local species. However, the data of species and their behavior in Indonesia is still lacking.

Method: Explorative research was conducted from April to September 2016 in Southern Minahasa district. Read More

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http://dx.doi.org/10.1155/2017/6313016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563419PMC
August 2017
6 Reads

Association between Virulence Factors and Extended Spectrum Beta-Lactamase Producing Compared to Nonproducing Isolates.

Interdiscip Perspect Infect Dis 2017 8;2017:7279830. Epub 2017 Jun 8.

Microbiology & Immunology Department, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.

is considered an important opportunistic multidrug-resistant pathogen. Extended spectrum -lactamases (ESBLs) and expression of a multitude of virulence factors may work in a harmony resulting in treatment failure. This study was undertaken to compare the virulence characteristics and genetic relatedness between ESBL and non-ESBL producing . Read More

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http://dx.doi.org/10.1155/2017/7279830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480045PMC
June 2017
10 Reads

Epidemiological and Clinical Parameters Features of Patients with Clonorchiasis in the Geum River Basin, Republic of Korea.

Interdiscip Perspect Infect Dis 2017 26;2017:7415301. Epub 2017 Apr 26.

Division of Malaria and Parasitic Diseases, Center for Immunology and Pathology, National Research Institute of Health, Centers for Disease Control and Prevention, Osong 28159, Republic of Korea.

This study was conducted to evaluate the infection rates of and laboratory findings in infected people. The 3,167 fecal samples, from nine villages in Okcheon-gun, were examined. Read More

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http://dx.doi.org/10.1155/2017/7415301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424194PMC
April 2017
32 Reads

Hematological Parameters and Hemozoin-Containing Leukocytes and Their Association with Disease Severity among Malaria Infected Children: A Cross-Sectional Study at Pawe General Hospital, Northwest Ethiopia.

Interdiscip Perspect Infect Dis 2017 19;2017:8965729. Epub 2017 Feb 19.

Department of Medical Laboratory Science and Pathology, College of Health Sciences, Jimma University, Jimma, Ethiopia.

Hematological parameter changes are the most common complications in malaria. We aimed to determine the hematological parameters and hemozoin-containing leukocytes and their association with disease severity in malaria infected children aged between 1 and 15 years. A facility-based cross-sectional study was conducted at Pawe General Hospital from July 31 to December 30, 2014. Read More

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https://www.hindawi.com/journals/ipid/2017/8965729/
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http://dx.doi.org/10.1155/2017/8965729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337349PMC
February 2017
18 Reads

Sulfated Glycans and Related Digestive Enzymes in the Zika Virus Infectivity: Potential Mechanisms of Virus-Host Interaction and Perspectives in Drug Discovery.

Authors:
Vitor H Pomin

Interdiscip Perspect Infect Dis 2017 19;2017:4894598. Epub 2017 Jan 19.

Program of Glycobiology, Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, 21941-590 Rio de Janeiro, RJ, Brazil; University Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, 21941-913 Rio de Janeiro, RJ, Brazil.

As broadly reported, there is an ongoing Zika virus (ZIKV) outbreak in countries of Latin America. Recent findings have demonstrated that ZIKV causes severe defects on the neural development in fetuses in utero and newborns. Very little is known about the molecular mechanisms involved in the ZIKV infectivity. Read More

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http://dx.doi.org/10.1155/2017/4894598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288528PMC
January 2017
5 Reads

Prevalence, Characteristics, and One-Year Follow-Up of Congenital Cytomegalovirus Infection in Isfahan City, Iran.

Interdiscip Perspect Infect Dis 2016 14;2016:7812106. Epub 2016 Dec 14.

Department of Pediatrics, Isfahan University of Medical Sciences, Isfahan, Iran.

Need of neonatal screening for (CMV) infection is under debate, in part because of limited data on importance of the disease regarding the prevalence of congenital CMV (cCMV) infection and associated morbidity and mortality. We aimed to evaluate the prevalence and prognosis of cCMV infection in Iran, where there is high maternal seroprevalence of CMV. . Read More

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http://dx.doi.org/10.1155/2016/7812106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192306PMC
December 2016
34 Reads

Antimicrobial Stewardship: A Cross-Sectional Survey Assessing the Perceptions and Practices of Community Pharmacists in Ethiopia.

Interdiscip Perspect Infect Dis 2016 22;2016:5686752. Epub 2016 Nov 22.

Department of Pharmaceutical Chemistry, School of Pharmacy, University of Gondar, Lideta kebele 16, P.O. Box 196, Gondar, Ethiopia.

. Community pharmacists are key healthcare professionals for antimicrobial stewardship programs owing to their role in dispensing of antimicrobials. The aim of the present study was to assess the perception and practices of community pharmacists towards antimicrobial stewardship (AMS) in Ethiopia. Read More

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http://dx.doi.org/10.1155/2016/5686752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138470PMC
November 2016
12 Reads

Clinical Significance of Molecular Diagnostic Tools for Bacterial Bloodstream Infections: A Systematic Review.

Interdiscip Perspect Infect Dis 2016 16;2016:6412085. Epub 2016 Nov 16.

School of Science, College of Science and Technology, University of Rwanda, BP 56, Huye, Rwanda.

Bacterial bloodstream infection (bBSI) represents any form of invasiveness of the blood circulatory system caused by bacteria and can lead to death among critically ill patients. Thus, there is a need for rapid and accurate diagnosis and treatment of patients with septicemia. So far, different molecular diagnostic tools have been developed. Read More

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http://dx.doi.org/10.1155/2016/6412085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128711PMC
November 2016
11 Reads

Retracted: Contamination of Hospital Water Supplies in Gilan, Iran, with and .

Interdiscip Perspect Infect Dis 2016 12;2016:4801509. Epub 2016 Oct 12.

[This retracts the article DOI: 10.1155/2015/809842.]. Read More

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http://dx.doi.org/10.1155/2016/4801509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080488PMC
October 2016
11 Reads

Evaluation and Verification of the Global Rapid Identification of Threats System for Infectious Diseases in Textual Data Sources.

Interdiscip Perspect Infect Dis 2016 6;2016:5080746. Epub 2016 Sep 6.

Defense Threat Reduction Agency, Fort Belvoir, VA, USA.

The Global Rapid Identification of Threats System (GRITS) is a biosurveillance application that enables infectious disease analysts to monitor nontraditional information sources (e.g., social media, online news outlets, ProMED-mail reports, and blogs) for infectious disease threats. Read More

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http://dx.doi.org/10.1155/2016/5080746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028852PMC
September 2016
11 Reads

Epidemiological Mapping of Human Onchocerciasis in Transmission Suspected Districts of Bale, Borena, and West Arsi Zones of Eastern Ethiopia.

Interdiscip Perspect Infect Dis 2016 25;2016:6937509. Epub 2016 Aug 25.

Ethiopian Public Health Institute (EPHI), Addis Ababa, Ethiopia.

Onchocerciasis is mainly found in western part of Ethiopia and there is no evidence of transmission in the east ward. However, some zones (Bale, Borena, and West Arsi) are suspected for transmission given the area has fast flowing rivers and is covered with vegetation. Therefore, this study was conducted to map onchocerciasis transmission in those zones. Read More

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http://dx.doi.org/10.1155/2016/6937509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014964PMC
September 2016
45 Reads

Predictors of Staphylococcus aureus Colonization and Results after Decolonization.

Interdiscip Perspect Infect Dis 2016 26;2016:4367156. Epub 2016 Jul 26.

Department of Orthopaedic Surgery, Cleveland Clinic, 9500 Euclid Avenue, A41, Cleveland, OH 44195, USA.

Protocols for the screening and decolonization of Staphylococcus aureus prior to total joint arthroplasty (TJA) have become widely adopted. The goals of this study were to determine: (1) whether implementation of a screening protocol followed by decolonization with mupirocin/vancomycin and chlorhexidine reduces the risk of revision compared with no screening protocol (i.e. Read More

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http://dx.doi.org/10.1155/2016/4367156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977396PMC
August 2016
16 Reads

Evaluation of Antimicrobial Resistance in Staphylococcus aureus Isolates by Years.

Interdiscip Perspect Infect Dis 2016 9;2016:9171395. Epub 2016 May 9.

Faculty of Medicine, Department of Pediatric Diseases, Yuzuncu Yil University, 65080 Van, Turkey.

Objective. Recently, community and hospital-acquired infections with Staphylococcus aureus have increased and raised antibiotic resistant isolates. In this study, we aimed to evaluate the antibiotic resistance profile of S. Read More

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http://dx.doi.org/10.1155/2016/9171395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876226PMC
June 2016
16 Reads
2 Citations

Using MALDI-TOF Mass Spectrometry to Identify Drug Resistant Staphylococcal Isolates from Nonhospital Environments in Brunei Darussalam.

Interdiscip Perspect Infect Dis 2016 3;2016:8685602. Epub 2016 Apr 3.

PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Gadong BE1410, Brunei Darussalam.

Drug resistant bacteria have been a growing threat to the community and hospitals due to the misuse of antibiotics by humans, industrialization, and lack of novel antimicrobials currently available. Little is known about the prevalence of drug resistant bacteria in nonhealthcare environments in Brunei Darussalam and about how antibiotic resistant genes are transferred within these environments. Human contact points from different types of environments in Brunei Darussalam, varying from urban to jungle settings, were swabbed and cultured onto selective media to isolate staphylococci bacteria before performing antimicrobial susceptibility testing on the isolates. Read More

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http://dx.doi.org/10.1155/2016/8685602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834169PMC
April 2016
15 Reads

Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen.

Interdiscip Perspect Infect Dis 2016 9;2016:5954394. Epub 2016 Mar 9.

Biology Department, Faculty of Education, Aden University, Aden, Yemen.

Plasmodium falciparum malaria is the most common infection in Yemen. The present study aims to investigate changes in hematological and hepatic function indices of P. falciparum infected individuals. Read More

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http://dx.doi.org/10.1155/2016/5954394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804037PMC
April 2016
9 Reads

The Optimal Management of Acute Febrile Encephalopathy in the Aged Patient: A Systematic Review.

Interdiscip Perspect Infect Dis 2016 17;2016:5273651. Epub 2016 Feb 17.

Department of Infectious Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 91388-13944, Iran.

The elderly comprise less than 13 percent of world population. Nonetheless, they represent nearly half of all hospitalized adults. Acute change in mental status from baseline is commonly seen among the elderly even when the main process does not involve the central nervous system. Read More

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http://dx.doi.org/10.1155/2016/5273651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773559PMC
March 2016
10 Reads

Impact of HIV Infection and Zidovudine Therapy on RBC Parameters and Urine Methylmalonic Acid Levels.

Interdiscip Perspect Infect Dis 2016 24;2016:5210963. Epub 2016 Feb 24.

Department of Haematology and Blood Transfusion, College of Medicine, University of Lagos, Idi-Araba, Lagos 100254, Nigeria.

Background. Anaemia is a common complication of human immunodeficiency virus (HIV) infection. The aim of this study was to investigate the impact of HIV infection and zidovudine on red blood cells (RBC) parameters and urine methylmalonic acid (UMMA) levels in patients with HIV infection. Read More

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http://dx.doi.org/10.1155/2016/5210963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773552PMC
March 2016
22 Reads

Correlation between Trichomonas vaginalis and Concurrency: An Ecological Study.

Interdiscip Perspect Infect Dis 2016 2;2016:5052802. Epub 2016 Feb 2.

Center for Studies in Demography and Ecology, University of Washington, 206 Raitt Hall, Box 353412, Seattle, WA 98195, USA.

Objective. There is a large variation in the prevalence of Trichomonas vaginalis (TV) between different countries and between racial groups within countries. Sexual partner concurrency may play a role. Read More

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http://dx.doi.org/10.1155/2016/5052802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754479PMC
March 2016
10 Reads

Ulcerative Colitis and Its Association with Salmonella Species.

Interdiscip Perspect Infect Dis 2016 20;2016:5854285. Epub 2016 Jan 20.

Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India.

Ulcerative colitis (UC) is characterized by presence of ulcer in colon and bloody diarrhea. The present study explores the possibility of association between Salmonella and ulcerative colitis. The present study comprised 59 cases of UC, 28 of colon cancer (CC), 127 of irritable bowel syndrome (IBS), and 190 of healthy control. Read More

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http://dx.doi.org/10.1155/2016/5854285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745578PMC
February 2016
12 Reads

Medical Device-Associated Candida Infections in a Rural Tertiary Care Teaching Hospital of India.

Interdiscip Perspect Infect Dis 2016 24;2016:1854673. Epub 2016 Jan 24.

Department of Microbiology, Rural Medical College, Pravara Institute of Medical Sciences (Deemed University), Loni, Maharashtra 413736, India.

Health care associated infections (HCAIs) add incrementally to the morbidity, mortality, and cost expected of the patient's underlying diseases alone. Approximately, about half all cases of HCAIs are associated with medical devices. As Candida medical device-associated infection is highly drug resistant and can lead to serious life-threatening complications, there is a need of continuous surveillance of these infections to initiate preventive and corrective measures. Read More

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http://dx.doi.org/10.1155/2016/1854673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745319PMC
February 2016
53 Reads

Circulating Interferon-Gamma Levels Are Associated with Low Body Weight in Newly Diagnosed Kenyan Non-Substance Using Tuberculosis Individuals.

Interdiscip Perspect Infect Dis 2016 5;2016:9415364. Epub 2016 Jan 5.

Department of Medical Laboratory Sciences, Masinde Muliro University of Science and Technology, P.O. Box 190, Kakamega 50100, Kenya.

Although interferon-gamma, interleukin-10, and adiponectin are key immunopathogenesis mediators of tuberculosis, their association with clinical manifestations of early stage disease is inconclusive. We determined interferon-gamma, interleukin-10, and adiponectin levels in clinically and phenotypically well-characterised non-substance using new pulmonary tuberculosis patients (n = 13) and controls (n = 14) from Kenya. Interferon-gamma levels (P < 0. Read More

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http://dx.doi.org/10.1155/2016/9415364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736369PMC
February 2016
17 Reads

Bacteriospermia and Its Impact on Basic Semen Parameters among Infertile Men.

Interdiscip Perspect Infect Dis 2016 6;2016:2614692. Epub 2016 Jan 6.

Department of Microbiology, Karpaga Vinayaga Institute of Medical Sciences and Research Centre, Chinna Kolambakkam Post, Madurantakam Taluk, Kanchipuram, Tamil Nadu 603 308, India.

Introduction. Semen analysis is considered as the surrogate marker for male fecundity while assessing infertile men. There are several reasons for altered semen quality and bacteriospermia could be one among them. Read More

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http://dx.doi.org/10.1155/2016/2614692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736773PMC
February 2016
12 Reads

Imaging Based Methods of Liver Fibrosis Assessment in Viral Hepatitis: A Practical Approach.

Interdiscip Perspect Infect Dis 2015 8;2015:809289. Epub 2015 Dec 8.

Section of Gastroenterology and Hepatology, Temple University Lewis Katz School of Medicine, Temple University Health System, 3440 N. Broad Street, Philadelphia, PA 19140, USA.

Liver fibrosis represents the repair mechanism in liver injury and is a feature of most chronic liver diseases. The degree of liver fibrosis in chronic viral hepatitis infections has major clinical implications and presence of advanced fibrosis or cirrhosis determines prognosis. Treatment initiation for viral hepatitis is indicated in most cases of advanced liver fibrosis and diagnosis of cirrhosis entails hepatology evaluation for specialized clinical care. Read More

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http://dx.doi.org/10.1155/2015/809289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686715PMC
January 2016
6 Reads

Comparison between Two Decades of Prevalence of Intestinal Parasitic Diseases and Risk Factors in a Brazilian Urban Centre.

Interdiscip Perspect Infect Dis 2015 25;2015:546705. Epub 2015 Nov 25.

Federal University of Ceará, Rua Monsenhor Furtado 177, Rodolfo Teófilo, 60430-350 Fortaleza, CE, Brazil.

Objectives. This study's objective was to compare the prevalence of intestinal parasites and associated risk factors in children in urban communities, in the Brazilian Northeast, between two decades. Methods. Read More

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http://dx.doi.org/10.1155/2015/546705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673330PMC
December 2015
6 Reads

Prevalence of Asymptomatic Brucellosis in Children 7 to 12 Years Old.

Interdiscip Perspect Infect Dis 2015 20;2015:187369. Epub 2015 Oct 20.

Pediatric Medicine Research Center, Qom University of Medical Sciences, Qom 3713649373, Iran.

Background. Brucellosis is one of the most common diseases of humans and animals and its clinical manifestations differ from asymptomatic infection to chronic illness associated with recurrence of symptoms. This study aimed to evaluate the prevalence of brucellosis in asymptomatic children 7 to 12 years old in Kahak, Iran. Read More

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http://dx.doi.org/10.1155/2015/187369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630393PMC
November 2015
30 Reads

Contamination of Hospital Water Supplies in Gilan, Iran, with Legionella pneumophila, Escherichia coli, and Pseudomonas aeruginosa.

Interdiscip Perspect Infect Dis 2015 7;2015:809842. Epub 2015 Sep 7.

Department of Microbiology, Islamic Azad University, Lahijan Branch, Lahijan, Iran.

This study is designed to determine the contamination degree of hospital water supplies with Pseudomonas aeruginosa, Legionella pneumophila, and E. coli in Gilan, Iran. Samples were collected directly into sterile containers and concentrated by centrifuge. Read More

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http://dx.doi.org/10.1155/2015/809842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576014PMC
October 2015
6 Reads

Breeding Sites of Aedes aegypti: Potential Dengue Vectors in Dire Dawa, East Ethiopia.

Interdiscip Perspect Infect Dis 2015 7;2015:706276. Epub 2015 Sep 7.

Department of Life Sciences, Dire Dawa University, P.O. Box 1362, Dire Dawa, Ethiopia.

Background and Objectives. Entomological survey was carried out from May-June to September-October 2014 to investigate the presence of dengue vectors in discarded tires and artificial water containers in houses and peridomestic areas. Methods. Read More

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http://dx.doi.org/10.1155/2015/706276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576013PMC
October 2015
15 Reads