Chest 2022 May 7. Epub 2022 May 7.
Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, University of Sydney, NSW, Australia; The University of Sydney, Faculty of Science, School of Psychology, Sydney, NSW, 2006, Australia; The University of Sydney, Brain and Mind Centre, Sydney, New South Wales, Australia.
Sleep disturbances are often cited as a primary reason for medicinal cannabis use and there is increasing clinical interest in the therapeutic potential of cannabinoids in treating sleep disorders. Burgeoning evidence suggests a role of the endocannabinoid system in regulating the circadian sleep-wake cycle, highlighting a potential avenue for developing novel therapeutics. Despite widespread use of cannabis products as sleep aids globally, robustly designed studies verifying efficacy in sleep-disordered populations are limited. Read More