27,956 results match your criteria Insomnia


The clinical effects of sleep restriction therapy for insomnia: A meta-analysis of randomised controlled trials.

Sleep Med Rev 2021 Apr 21;58:101493. Epub 2021 Apr 21.

Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, UK. Electronic address:

Sleep restriction therapy (SRT) is an established treatment for insomnia that has been used in clinical practise for over 30 y. It is commonly delivered as part of multicomponent cognitive-behavioural therapy (CBT-I) but has also been linked to beneficial effects as a standalone intervention. In order to quantify the efficacy of SRT we performed a comprehensive meta-analysis of randomised controlled trials (RCTs) comparing SRT to minimally active or non-active control groups. Read More

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Sleep Difficulties among Mexican Adolescents: Subjective and Objective Assessments of Sleep.

Behav Sleep Med 2021 May 13:1-15. Epub 2021 May 13.

Department of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan.

: Self-reported sleep difficulties, such as insomnia symptoms, have been reported among adolescents. Yet, studies of their prevalence and correlates are scarce among Latin Americans. This study sought (1) to describe associations between sociodemographic and lifestyle factors with self-reported sleep difficulties and (2) to examine associations between self-reported sleep difficulties and actigraphy-based sleep. Read More

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Knowledge to action: a scoping review of approaches to educate primary care providers in the identification and management of routine sleep disorders.

J Clin Sleep Med 2021 May 13. Epub 2021 May 13.

Flinders Health and Medical Research Institute Sleep Health / Adelaide Institute of Sleep Health, College of Medicine and Public Health, Flinders University, Adelaide, Australia.

Study Objectives: The referral burden on healthcare systems for routine sleep disorders could be alleviated by educating primary care providers (PCPs) to diagnose and manage patients with sleep health issues. This requires effective professional education strategies and resources. This scoping review examined the literature on existing approaches to educate PCPs in sleep health management. Read More

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Post-ICU Care in the Outpatient Setting.

Am Fam Physician 2021 May;103(10):590-596

University of Iowa Carver College of Medicine, Iowa City, IA, USA.

More than 5 million patients in the United States are admitted to intensive care units (ICUs) annually, and an increasing percentage of patients treated in the ICU survive to hospital discharge. Because these patients require follow-up in the outpatient setting, family physicians should be prepared to provide ongoing care and screening for post-ICU complications. Risk factors for complications after ICU discharge include previous ICU admissions, preexisting mental illness, greater number of comorbidities, and prolonged mechanical ventilation or higher opioid exposure while in the ICU. Read More

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[Literature research and traditional Chinese medicine properties of Aspalathus linearis].

Zhongguo Zhong Yao Za Zhi 2021 Apr;46(8):1960-1966

School of Chinese Medicine, Beijing University of Chinese Medicine Beijing 100029, China.

Aspalathus linearis is a needle-shaped shrub that grows in the Cedarberg mountains in southern South Africa, with an extremely high medicinal value. In 2014, China has approved A. linearis as a new food material. Read More

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[Literature research of Passiflora incarnata and discussion of its traditional Chinese medicine properties].

Zhongguo Zhong Yao Za Zhi 2021 Apr;46(8):1943-1950

School of Chinese Medicine, Beijing University of Chinese Medicine Beijing 100029, China.

Based on the research literatures of Passiflora incarnata and the theory of traditional Chinese medicine, the paper discussed the traditional Chinese medicinal properties of P. incarnate, so as to provide a theoretical basis for the compatibility and application of P. incarnata. Read More

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Acute psychological impact of coronavirus disease 2019 outbreak among psychiatric professionals in China: a multicentre, cross-sectional, web-based study.

BMJ Open 2021 May 11;11(5):e047828. Epub 2021 May 11.

Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China

Objectives: To assess the magnitude of mental health outcomes and associated factors among psychiatric professionals in mental health services during COVID-19 in China.

Design, Setting And Participants: This cross-sectional, survey-based, region-stratified study collected demographic data and mental health measurements from psychiatric professionals in 34 hospitals between 29 January and 7 February 2020, in China. Hospitals equipped with fever clinics or deployed on wards for patients with COVID-19 were eligible. Read More

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Using Prazosin to Treat Posttraumatic Stress Disorder and Associations: A Systematic Review.

Psychiatry Investig 2021 May 14. Epub 2021 May 14.

Department of Psychiatry, School of Medicine, State University of Campinas, Campinas, Brazil.

Objective: A central adrenergic hyperactivation is described in the neurobiology of posttraumatic stress disorder (PTSD) with probable variable symptomatic impact. Few studies have evaluated using the alpha-1 adrenergic antagonist prazosin for such symptoms; however, given the likely pathophysiology involved, this drug may play an important role in the pharmacological approach to PTSD.

Methods: This study assessed articles already published on the use of prazosin through a systematic review along a timeline in view of the symptomatic target of difficult access by standardized treatments. Read More

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Depressive and stress symptoms in insomnia patients predict group cognitive-behavioral therapy for insomnia long-term effectiveness: A data-driven analysis.

J Affect Disord 2021 Apr 24;289:117-124. Epub 2021 Apr 24.

Sleep Disorder Center, San Raffaele Hospital Milan, Italy.

Background: Insomnia Disorder is characterized by high degree of phenotypic heterogeneity, that might influence treatment response.

Methods: 123 of 294 insomnia patients initially recruited (66.7% females, age=40. Read More

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Circadian factors in comorbid insomnia and sleep apnea (COMISA).

J Clin Sleep Med 2021 May 12. Epub 2021 May 12.

The Adelaide Institute for Sleep Health, Flinders Health and Medical Research Institute: Sleep Health, College of Education, Psychology and Social Work, Flinders University.

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Prevalence of Obstructive Sleep Apnea Among Saudi Pilots.

Nat Sci Sleep 2021 4;13:537-545. Epub 2021 May 4.

Somnogen Canada Inc., Toronto, Ontario, M6H 1C5, Canada.

Purpose: To evaluate the presence of obstructive sleep apnea (OSA), using home sleep testing in pilots and first officers in Saudi-based airlines. This will allow for proper diagnosis and management of OSA in that group which can help in minimizing any possible aviation accidents related to sleep disturbances secondary to OSA.

Materials And Methods: This is a cross-sectional study conducted through Saudi-based aviation among pilots and first officers who were in service, active, and flying short- to medium-haul flights. Read More

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Predictive factors of insomnia during the COVID-19 pandemic in Bangladesh: a GIS-based nationwide distribution.

Sleep Med 2021 Apr 26. Epub 2021 Apr 26.

CHINTA Research Bangladesh (Centre for Health Innovation, Networking, Training, Action and Research - Bangladesh), Savar, Dhaka, Bangladesh; Department of Public Health and Informatics, Jahangirnagar University, Savar, Dhaka, Bangladesh. Electronic address:

Background: In a densely populated country like Bangladesh, mental health-related burden and associated adverse outcomes are quite prevalent. However, exploration of sleep-related issues in general, and more specifically of insomnia during the COVID-19 pandemic has been scarce and restricted to a single location. The present study investigated the prevalence of insomnia and its predictive factors in the general population, and included Geographic Information System (GIS) analysis to identify regional heterogeneities of insomnia in Bangladesh. Read More

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Corrigendum to "Defificits in attention performance are associated with insufficiency of slow-wave sleep in insomnia" [Sleep Med 24 (2016) 124-130].

Sleep Med 2021 May 8. Epub 2021 May 8.

Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Translational Neuroscience Center, Department of Otolaryngology, West China Hospital, Sichuan University, Chengdu, China. Electronic address:

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Overview of sleep management during COVID-19.

Authors:
Philip M Becker

Sleep Med 2021 Apr 24. Epub 2021 Apr 24.

Sleep Medicine Associates of Texas, Department of Psychiatry, University of Texas Medical Center at Dallas, 12327 Brittany Circle, Dallas, TX 75230 USA. Electronic address:

The sleep of millions has suffered during the global COVID-19 pandemic. Prevalence rates of 20-45% are reported globally for insomnia symptoms during the pandemic. Affected populations include the public and health care workers. Read More

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Social distancing during the COVID-19 pandemic and health-related quality of life among esophageal cancer survivors.

Acta Oncol 2021 May 11:1-8. Epub 2021 May 11.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

Purpose: The purpose was to investigate whether social distancing during the COVID-19 pandemic reduced health-related quality of life (HRQL) in esophageal cancer patients and if so, to identify factors related to the HRQL changes.

Methods: A prospective Swedish nationwide study of patients who undergone surgery for esophageal cancer between 2013 and 2019. Telephone interviews were conducted 5 weeks and 13 weeks after the introduction of social distancing recommendations. Read More

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Mental Health in Health Professionals in the COVID-19 Pandemic.

Adv Exp Med Biol 2021 ;1318:737-757

Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.

The coronavirus disease 2019 (COVID-19) pandemic has posed enormous challenges to the healthcare systems worldwide, which are mainly shouldered by healthcare workers from all professions. This chapter outlines the potential stressors of the COVID-19 pandemic for health professionals and describes possible consequences for their mental health as well as potential interventions and coping strategies. The chapter is based on preliminary research on the psychosocial implications of the COVID-19 pandemic in health professionals and is complemented by findings from previous outbreaks of high-risk infectious diseases. Read More

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Causal influences of neuroticism on mental health and cardiovascular disease.

Hum Genet 2021 May 11. Epub 2021 May 11.

Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, 200030, China.

We investigated the relationship between neuroticism and 16 mental and 18 physical traits using summary results of genome-wide association studies for these traits. LD score regression was used to investigate genetic correlations between neuroticism and the 34 health outcomes. Mendelian randomization was performed to investigate mutual causal relationships between neuroticism and the 34 health outcomes. Read More

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Characterization of pharmaco-EEG fingerprint and sleep-wake profiles of Lavandula angustifolia Mill. essential oil inhalation and diazepam administration in rats.

J Ethnopharmacol 2021 May 7:114193. Epub 2021 May 7.

Division of Biological Science, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand; Biosignal Research Center for Health, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand. Electronic address:

Ethnopharmacological Relevance: Lavandula angustifolia Mill. essential oil (Lavender EO) has a long history of medicinal use and is particularly claimed to possess anxiolytic and sedative properties. Lavender EO aromatherapy has been used to reduce distress and improve insomnia naturally. Read More

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Benzodiazepine Use in Opioid Maintenance Treatment Programme: Risks and Clinical Outcomes.

Acta Med Port 2021 Mar 1;34(3):209-216. Epub 2021 Mar 1.

Drug Addiction Treatment Centre. Agualva-Cacém. Cacém. Portugal.

Introduction: The co-association of benzodiazepines and opioids is associated with an increased risk of overdose, death, and poorer psychosocial prognosis. The aim of this study is to characterize the prevalence, pattern of use, and primary clinical outcomes in benzodiazepines users in a public opioid maintenance treatment unit.

Material And Methods: We conducted a cross-sectional study involving 236 patients treated with opioid substitutes (methadone and buprenorphine). Read More

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Developing a real-world evidence base for prescribed cannabis in the United Kingdom: preliminary findings from Project Twenty21.

Psychopharmacology (Berl) 2021 May 10. Epub 2021 May 10.

Imperial College London, Burlington Danes Building, Hammersmith Hospital, Du Cane Rd, White City, London, W12 0NN, UK.

The therapeutic potential of medical cannabis to treat a variety of conditions is becoming increasingly recognised. Globally, a large number of countries have now legalised cannabis for medical uses and a substantial number of patients are able to access their medications. Yet in the UK, where medical cannabis was legalised in November 2018, only a handful of NHS prescriptions have been written, meaning that most patients are unable to access the medicine. Read More

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Prevalence of and Trends in the Co-Existence of Obesogenic Behaviors in Adolescents From 15 Countries.

Front Pediatr 2021 22;9:664828. Epub 2021 Apr 22.

Applied Biostatistics Laboratory, University of Michigan School of Nursing, Ann Arbor, MI, United States.

The global epidemic of pediatric obesity is well-known, but data on co-existence of obesogenic behaviors are limited. We aim to report the prevalence of and trends in the co-existence of obesogenic behaviors in adolescents from 15 countries. This study was based on the Global School-based Student Health Survey 2003-2017 and included 121,963 adolescents aged 12-15 years from 15 countries where at least 2 cross-sectional surveys were conducted. Read More

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Hypnotic Effect of . Hydroalcoholic Extract in Pentobarbital-Treated Mice.

Neurol Res Int 2021 21;2021:5521019. Epub 2021 Apr 21.

Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Current drugs used in the management of insomnia are associated with side effects. The use of medicinal herbs for insomnia treatment has recently been suggested.

Objective: The present study aimed to determine the hypnotic activity of the hydroalcoholic extract of . Read More

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Mental Health During the First Weeks of the COVID-19 Pandemic in the United States.

Front Psychiatry 2021 22;12:561898. Epub 2021 Apr 22.

Social, Cognitive, and Affective Neuroscience Lab, Department of Psychiatry, University of Arizona College of Medicine, Tucson, AZ, United States.

By March 2020, the World Health Organization declared the COVID-19 crisis as a worldwide pandemic and many local governments instituted stay-at-home orders and closed non-essential businesses. Within the United States, tens of millions of workers lost their jobs and financial security during the first few weeks of the national response, in an attempt to slow the global pandemic. Because of the enormity of the pandemic and its potential impact on mental health, the objective of the present study was to document the prevalence of mental health problems and their association with pandemic-related job loss during the third week of the nationwide shutdown. Read More

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Insomnia Moderates the Relationship Between Amyloid-β and Cognitive Decline in Late-Life Adults without Dementia.

J Alzheimers Dis 2021 May 5. Epub 2021 May 5.

Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China.

Background: It is suggested that not all individuals with elevated Aβ will develop dementia or cognitive impairment. Environment or lifestyle might modulate the association of amyloid pathology with cognition. Insomnia is a risk factor of cognitive disorders including Alzheimer's disease. Read More

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Psychiatric disorders as risk factors for type 2 diabetes: an umbrella review of systematic reviews with and without meta-analyses.

Diabetes Res Clin Pract 2021 May 6:108855. Epub 2021 May 6.

Department of Psychology, University of Southern Denmark, Odense, Denmark; STENO Diabetes Centre Odense, Odense University Hospital, Odense, Denmark; School of Psychology, Deakin University, Geelong, Australia. Electronic address:

Having a psychiatric disorder may increase the risk of developing type 2 diabetes[T2D] and this umbrella review aims to determine whether people with a psychiatric disorder have an increased risk of developing T2D and to investigate potential underlying mechanisms. A literature search was performed to identify systematic reviews of longitudinal studies investigating different psychiatric disorders as risk factors for incident T2D in humans (≥18 years). A total of 8,612 abstracts were identified, 180 full-text articles were read, and 25 systematic reviews were included. Read More

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Sex Differences, Sleep Disturbance and Risk of Persistent Pain Associated With Groin Hernia Surgery: A Nationwide Register-Based Cohort Study.

J Pain 2021 May 5. Epub 2021 May 5.

Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden; Department of Surgery, Skåne University Hospital, Malmö, Sweden.

Persistent pain after groin hernia repair is a major health problem. Sleep disturbance is associated with heightened pain sensitivity. The main objective of this study was to examine the role of sleep disturbance in the development and long-term maintenance of chronic postherniorrhaphy inguinal pain (CPIP), with exploration of sex differences. Read More

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The effect of sleep-wake intraindividial variability in digital cognitive behaviour therapy for insomnia: A mediation analysis of a large-scale RCT.

Sleep 2021 May 8. Epub 2021 May 8.

Department of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.

Study Objectives: Digital Cognitive Behavioural Therapy for Insomnia (dCBT-I) is an effective treatment for insomnia. However, less is known about mediators of its benefits. The aim of the present study was to test if intraindividual variability in sleep (IIV) was reduced with dCBT-I, and whether any identified reduction was a mediator of dCBT-I on insomnia severity and psychological distress. Read More

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The psychological symptom burden in partners of pancreatic cancer patients: a population-based cohort study.

Support Care Cancer 2021 May 8. Epub 2021 May 8.

Unit of Survivorship & Inequality in Cancer, Danish Cancer Society Research Centre, Danish Cancer Society, Copenhagen, Denmark.

Purpose: Pancreatic cancer (PC) has high morbidity and mortality and is stressful for patients and their partners. We investigated the psychological symptom burden in partners of PC patients.

Methods: We followed 5774 partners of PC patients diagnosed from 2000 to 2016 up for first redeemed prescriptions of antidepressants or hospital admission, anxiolytics, and hypnotics as proxies for clinical depression, anxiety, and insomnia and compared them with 59,099 partners of cancer-free spouses. Read More

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Effect of early intervention for anxiety on sleep outcomes in adolescents: a randomized trial.

Eur Child Adolesc Psychiatry 2021 May 7. Epub 2021 May 7.

Regional Centre for Child and Youth Mental Health and Child Welfare, Norwegian Research Center, NORCE, Bergen, Norway.

The potential effect of early intervention for anxiety on sleep outcomes was examined in a sample of adolescents with anxiety (N = 313, mean 14.0 years, SD = 0.84, 84% girls, 95. Read More

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Estimating the cumulative risk of postnatal depressive symptoms: the role of insomnia symptoms across pregnancy.

Soc Psychiatry Psychiatr Epidemiol 2021 May 7. Epub 2021 May 7.

Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Mannerheimintie 166, P. O. Box 30, 00271, Helsinki, Finland.

Purpose: Insomnia symptoms during late pregnancy are a known risk for postnatal depressive symptoms (PDS). However, the cumulative effect of various risk factors throughout pregnancy has not been explored. Our aim was to test how various insomnia symptoms (sleep latency, duration, quality, frequent night awakenings, early morning awakenings) and other risk factors (e. Read More

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