25,342 results match your criteria Insomnia


Sex-Specific Impact of Pain Severity, Insomnia, and Psychosocial Factors on Disability due to Spinal Degenerative Disease.

Pain Res Manag 2020 6;2020:8496527. Epub 2020 May 6.

Department of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, Tokyo 113-8431, Japan.

Purpose: Pain experience due to spinal degenerative disease decreases activity of daily living and quality of life. The present cross-sectional study was aimed at examining the sex-specific impact of pain severity, psychosocial factors, and insomnia on the disability due to chronic pain arising from spinal degenerative disease.

Methods: In total, 111 outpatients with chronic spinal degenerative on initial diagnosis were analyzed. Read More

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http://dx.doi.org/10.1155/2020/8496527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229535PMC

A brief sleep focused psychoeducation program for sleep-related outcomes in new mothers: A randomised controlled trial.

Sleep 2020 May 26. Epub 2020 May 26.

Sleep and Circadian Research Group (CIRUS) and NeuroSleep Centre of Research Excellence, Woolcock Institute of Medical Research, University of Sydney.

Study Objectives: Poor sleep is commonly problematic during pregnancy and postpartum and is associated with depression. This trial investigated the efficacy of prenatal brief, group sleep psychoeducation in improving postpartum maternal sleep and depression.

Methods: 215 healthy expectant first-time mothers were cluster randomised (1:1) to receive either a 2 x 1. Read More

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http://dx.doi.org/10.1093/sleep/zsaa101DOI Listing

Psychologic stress and disease activity in patients with inflammatory bowel disease: A multicenter cross-sectional study.

PLoS One 2020 26;15(5):e0233365. Epub 2020 May 26.

Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

Background And Aims: Psychologic stress can affect the pathogenesis of inflammatory bowel disease (IBD), but the precise contribution of psychologic stress to IBD remains unclear. We investigated the association of psychologic stress with disease activity in patients with IBD, especially in terms of mental state and sleep condition.

Methods: This was a multi-center observational study comprising 20 institutions. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233365PLOS

Associations between widespread pain and sleep quality in people with HIV.

J Acquir Immune Defic Syndr 2020 May 21. Epub 2020 May 21.

Minneapolis Veterans Affairs Health Care System, and University of Minnesota, Minneapolis/USA.

Background: We investigate the association of widespread pain with sleep quality among people with HIV (PWH) and HIV-negative controls.

Setting: UK-based cohort.

Methods: Pain information was collected through a pain mannikin identifying affected body sites; pain was classified as widespread if pain was reported in >4 of 5 body regions and in >7 of 15 body sites, and as regional otherwise. Read More

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http://dx.doi.org/10.1097/QAI.0000000000002410DOI Listing

The effect of psychological factors on pain, function and quality of life in patients with rotator cuff tendinopathy: A systematic review.

Musculoskelet Sci Pract 2020 Jun 29;47:102173. Epub 2020 Apr 29.

Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong. Electronic address:

Background: Psychological factors may affect the pain level, shoulder function and quality of life in patients with rotator cuff tendinopathy.

Objective: To systematically review the prevalence of psychological factors reported in patients with rotator cuff tendinopathy; and to determine the association between psychological factors and pain, function and quality of life in patients with rotator cuff tendinopathy.

Study Design: Systematic review METHODS: Pubmed, Embase, CINAHL and Web of Science were systematically searched from inception to June 2019. Read More

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http://dx.doi.org/10.1016/j.msksp.2020.102173DOI Listing

The Prevalence and Incidence of Insomnia in Korea during 2005 to 2013.

Psychiatry Investig 2020 May 27. Epub 2020 May 27.

Department of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.

Objective: The aim of this study was to estimate the progress of insomnia prevalence and incidence over the past several years. Also, this study compared survival rates between individuals with and without insomnia.

Methods: The National Health Insurance Service-National Sample Cohort (NHIS-NSC) from 2002-2013 was used for this study. Read More

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http://dx.doi.org/10.30773/pi.2019.0218DOI Listing

Challenges and Opportunities in Insomnia Disorder.

Int J Neurosci 2020 May 23:1-12. Epub 2020 May 23.

Ursinus College, Collegeville, PA, USA.

Insomnia disorder is a prevalent, often unrecognized condition that affects millions. This clinical disorder is characterized by difficulty initiating or maintaining sleep over a sustained period. In fact, insomnia disorder affects much more than sleep; it increases the risk for developing serious medical and psychiatric comorbidities and can exacerbate existing conditions. Read More

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http://dx.doi.org/10.1080/00207454.2020.1773460DOI Listing

Suspected Aripiprazole-induced neutropenia in a geriatric patient: a case report.

BMC Geriatr 2020 May 24;20(1):179. Epub 2020 May 24.

Department of Psychiatry, Kern Medical Center, 1700 Mount Vernon Avenue, Bakersfield, CA, 93306, USA.

Background: Aripiprazole, a third-generation antipsychotic medication, has been used to treat a range of psychiatric disorders. According to the U.S. Read More

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http://dx.doi.org/10.1186/s12877-020-01514-xDOI Listing

[Effects of occupational stress and related factors on insomnia occurrence of workers in chip manufacturing industry].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2020 Apr;38(4):259-262

Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.

To investigate the prevenlence of insomnia on workers and related influcecing factors in chip manufacturing industry. By using cluster sampling method, 2 251 workers in chip manufacturing industry were selected as study subjects. The simple Job Demand-Control model Questionnnaire (JDC) , Effort-Reword Imbalance (ERI) Questionnnaire and Insomnia Symptoms Scale were used to evaluate JDC occupational stress, ERI occupational stress and insomnia symptoms respectively. Read More

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http://dx.doi.org/10.3760/cma.j.cn121094-20190219-00052DOI Listing

Identifying Modifiable Factors Linking Parenting and Sleep in Racial/Ethnic Minority Children.

J Pediatr Psychol 2020 May 24. Epub 2020 May 24.

Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia.

Background: Young children from racial and ethnic minority backgrounds are at risk for poor sleep, yet few studies have tested behavioral interventions in diverse samples. This study tests factors that could contribute to associations between parenting skills and child sleep to inform interventions for children at risk of poor sleep outcomes. Specifically, we examined household chaos, caregiver sleep knowledge, and caregiver sleep quality as putative mediators that may be relevant to interventions seeking to improve child sleep. Read More

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http://dx.doi.org/10.1093/jpepsy/jsaa034DOI Listing

Shorter sleep duration is associated with lower GABA levels in the anterior cingulate cortex.

Sleep Med 2020 Feb 28;71:1-7. Epub 2020 Feb 28.

Ewha Brain Institute, Ewha W. University, Seoul, South Korea; Department of Brain and Cognitive Sciences, Ewha W. University, Seoul, South Korea. Electronic address:

Background: Alterations in the levels of gamma-aminobutyric acid (GABA) and glutamate + glutamine (Glx), which are major inhibitory and excitatory neurotransmitters, respectively, are frequently associated with insomnia. Previous reports also suggested the involvement of the anterior cingulate cortex (ACC) and medial prefrontal cortex (mPFC) in insomnia and shorter sleep duration. In the current study, we investigated whether the GABA and Glx levels were altered in the ACC/mPFC in subclinical insomnia while focusing on the sleep duration. Read More

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http://dx.doi.org/10.1016/j.sleep.2020.02.018DOI Listing
February 2020

Overview of sleep disturbances and their management in Parkinson plus disorders.

J Neurol Sci 2020 May 8;415:116891. Epub 2020 May 8.

Department of Neurology, National Institute of Mental Health & Neurosciences (NIMHANS), Hosur Road, Bangalore, Karnataka 560029, India. Electronic address:

Sleep disturbance is one of the commonly reported non-motor symptoms in patients with Parkinson's disease (PD) as well as in Parkinson plus disorders such as multiple system atrophy (MSA), dementia with Lewy bodies (DLB), progressive supranuclear palsy (PSP), and corticobasal syndrome (CBS). Although there is a wealth of literature on sleep disturbances in PD, the same is not robust on the Parkinson plus disorders. This article aims to comprehensively review the sleep disturbances in Parkinson plus disorders. Read More

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http://dx.doi.org/10.1016/j.jns.2020.116891DOI Listing

Sleep disturbance is associated with an increased risk of menstrual problems in female Chinese university students.

Sleep Breath 2020 May 23. Epub 2020 May 23.

Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.

Purpose: We aimed to investigate the association between sleep disturbance and menstrual problems in female Chinese university students.

Methods: A convenience sample of 1006 female university students participated in this study. Sleep duration, sleep quality, and insomnia symptoms were assessed by the Pittsburgh Sleep Quality Index and the Insomnia Severity Index. Read More

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http://dx.doi.org/10.1007/s11325-020-02105-1DOI Listing

What have antidepressants been tested for? A systematic review.

Int J Risk Saf Med 2020 May 21. Epub 2020 May 21.

Institute for Scientific Freedom, Copenhagen, Denmark.

Background: Antidepressants are much used and have been tested for many conditions.

Objective: To investigate the type of diagnoses in placebo-controlled trials apart from depression and anxiety.

Methods: This was a systematic review. Read More

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http://dx.doi.org/10.3233/JRS-200006DOI Listing

A Previously Healthy Adolescent With Acute Psychosis and Severe Hyperhidrosis.

Pediatrics 2020 May 22. Epub 2020 May 22.

Stanford University School of Medicine and.

A previously healthy 15-year-old boy presented with 3 months of progressive psychosis, insomnia, back and groin pain, and hyperhidrosis. On examination, the patient was disheveled, agitated, and soaked with sweat, with systolic blood pressure in the 160s and heart rate in the 130s. Aside from occasional auditory and visual hallucinations, his neurologic examination was normal. Read More

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http://dx.doi.org/10.1542/peds.2019-3786DOI Listing

Disrupted sleep maintenance is associated with altered circadian phase and phase angle in community-dwelling adults.

Sleep Med 2020 Feb 29. Epub 2020 Feb 29.

Department of Psychiatry, Kangwon National University Hospital, Chunchon, South Korea; Department of Psychiatry, Kangwon National University School of Medicine, Chunchon, South Korea. Electronic address:

Objective: We aimed to compare the sleep onset, dim light melatonin onset (DLMO) and phase angle (PA) between sleep onset and DLMO of insomnia patients with those of controls, and to examine the difference in these parameters in relation to objective sleep quality.

Methods: Participants were recruited from three Public Health Centers in Korea. Actigraphy recordings were conducted for seven days. Read More

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http://dx.doi.org/10.1016/j.sleep.2020.02.017DOI Listing
February 2020

Evidence Base of Clinical Studies on Qi Gong: A Bibliometric Analysis.

Complement Ther Med 2020 May 6;50:102392. Epub 2020 Apr 6.

Centre for Evidence Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China; Institute of Integrated Traditional Chinese Medicine and Western Medicine, Guangzhou Medical University, Guangzhou, China. Electronic address:

Objective: This bibliometric study aimed to systematically and comprehensively summarize the volume, breadth and evidence for clinical research on Qigong. And this bibliometric analysis also can provide the evidence of this field.

Design: Bibliometric analysis. Read More

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http://dx.doi.org/10.1016/j.ctim.2020.102392DOI Listing

Pediatric Prevention: Sleep Dysfunction.

Pediatr Clin North Am 2020 Jun;67(3):559-571

Center for Behavioral Health, 13460 Walsh Drive, Boys Town, NE 68010, USA.

This article addresses the essential role of sleep in the medical, emotional, behavioral, and cognitive health of children. Sleep disorders common among children are defined along with the most common sleep concerns reported by caregivers. Prevention and intervention strategies are described. Read More

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http://dx.doi.org/10.1016/j.pcl.2020.02.010DOI Listing

Better Objective Sleep Was Associated with Better Subjective Sleep and Physical Activity; Results from an Exploratory Study under Naturalistic Conditions among Persons with Multiple Sclerosis.

Int J Environ Res Public Health 2020 May 18;17(10). Epub 2020 May 18.

Center of Affective, Stress and Sleep Disorders (ZASS), University of Basel, Psychiatric Clinics (UPK), 4002 Basel, Switzerland.

Persons with multiple sclerosis (PwMS) often complain about sleep problems. There is less known about objective sleep-electroencephalography (EEG) dimensions within naturalistic conditions (i.e. Read More

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http://dx.doi.org/10.3390/ijerph17103522DOI Listing

Anhedonia to Gentle Touch in Fibromyalgia: Normal Sensory Processing but Abnormal Evaluation.

Brain Sci 2020 May 18;10(5). Epub 2020 May 18.

Center for Social and Affective Neuroscience, Linköping University, 58185 Linköping, Sweden.

Social touch is important for interpersonal interaction. Gentle touch and slow brushing are typically perceived as pleasant, the degree of pleasantness is linked to the activity of the C-tactile (CT) fibers, a class of unmyelinated nerves in the skin. The inability to experience pleasure in general is called anhedonia, a common phenomenon in the chronic pain condition fibromyalgia. Read More

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http://dx.doi.org/10.3390/brainsci10050306DOI Listing

Mechanisms for the reduction of caffeine consumption: What, how and why.

Drug Alcohol Depend 2020 May 8;212:108024. Epub 2020 May 8.

University of Auckland, New Zealand.

Background: Anecdotal evidence suggests consumers of caffeine self-administer strategies to reduce consumption, but little is known of what these strategies are or how they are implemented. This study aimed to understand the lived experience of reducing caffeine consumption including specific techniques (what) and implementation strategies (how), harm and withdrawal symptoms (why).

Methods: We developed a classification system through an inductive and deductive approach and applied it to a large dataset derived from online sources. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2020.108024DOI Listing

Chaihu-Longgu-Muli decoction relieves epileptic symptoms by improving autophagy in hippocampal neurons.

J Ethnopharmacol 2020 May 19. Epub 2020 May 19.

Provincial Key Laboratory of TCM Diagnostics, Hunan University of Chinese Medicine, NO.300, Xueshi Road, Changsha, Hunan Province, 410208, China. Electronic address:

Ethnopharmacological Relevance: Chaihu-Longgu-Muli decoction (CLMD) is a well-known ancient formula in traditional Chinese medicine (TCM) to relieve disorder, clear away heat, tranquilize the mind and allay excitement. It has been used for the therapy of neuropsychiatric disorders such as epilepsy, dementia, insomnia, anxiety, and depression for several centuries in China.

Aim Of The Study: This paper is based on the assumption that the mechanism by which CLMD relieves epileptic symptoms in rats is associated with improving autophagy. Read More

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http://dx.doi.org/10.1016/j.jep.2020.112990DOI Listing

Relationship between sleep characteristics and markers of inflammation in Swedish women from the general population.

J Sleep Res 2020 May 22:e13093. Epub 2020 May 22.

Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.

Systemic inflammation is thought to mediate the link between sleep and cardiovascular outcomes, but previous studies on sleep habits and inflammation markers have found inconsistent results. This study investigated the relationship between sleep characteristics and C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor α (TNFα). A representative sample of 319 Swedish women was randomly selected from the general population for in-home polysomnography, sleep questionnaire and blood samples. Read More

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http://dx.doi.org/10.1111/jsr.13093DOI Listing

Insomnia Among Elderly Primary Care Patients in India.

Prim Care Companion CNS Disord 2020 May 21;22(3). Epub 2020 May 21.

Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.

Objective: To assess insomnia and its health correlates among elderly primary care patients in India.

Methods: A multicenter, cross-sectional survey was administered to 1,770 elderly primary care patients from 71 government primary health centers in Kerala, India, from May to December 2016. Insomnia was evaluated using the Insomnia Severity Index. Read More

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http://dx.doi.org/10.4088/PCC.19m02581DOI Listing

Sleep problems in adolescents with CFS: A case-control study nested within a prospective clinical cohort.

Clin Child Psychol Psychiatry 2020 May 22:1359104520918364. Epub 2020 May 22.

Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

Sleep problems have a negative impact on a range of outcomes and are very common in adolescents with chronic fatigue syndrome (CFS). We aimed to (a) establish whether adolescents with CFS have more self-reported sleep problems than illness controls as well as healthy controls, (b) investigate changes in sleep problems and (c) explore the extent to which sleep problems at baseline predict fatigue and functioning at follow-up in adolescents with CFS. The Insomnia Scale was completed by 121 adolescents with CFS, 78 healthy adolescents and 27 adolescents with asthma. Read More

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http://dx.doi.org/10.1177/1359104520918364DOI Listing

A descriptive analysis of pediatric post-tonsillectomy pain and recovery outcomes over a 10-day recovery period from 2 randomized, controlled trials.

Pain Rep 2020 Mar-Apr;5(2):e819. Epub 2020 Mar 6.

Department of Pain Medicine, Palliative Care and Integrative Medicine, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN, USA.

Pediatric tonsillectomy involves an often painful and lengthy recovery period, yet the extended recovery process is largely unknown. This article describes postoperative recovery outcomes for 121 children aged 4 to 15 (mean 6.6 years, SD = 2. Read More

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http://dx.doi.org/10.1097/PR9.0000000000000819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209815PMC

Cognitive behavioural therapy for insomnia reduces sleep apnoea severity: a randomised controlled trial.

ERJ Open Res 2020 Apr 17;6(2). Epub 2020 May 17.

The Adelaide Institute for Sleep Health: a Centre of Research Excellence, College of Medicine and Public Health, Flinders University, Adelaide, Australia.

Insomnia and obstructive sleep apnoea (OSA) frequently co-occur and may be causally related through sleep fragmentation and/or hyperarousal mechanisms. Previous studies suggest that OSA treatment can improve insomnia severity. However, the effect of insomnia treatment on OSA severity has not been investigated. Read More

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http://dx.doi.org/10.1183/23120541.00161-2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231124PMC

Gene as a Candidate Gene in Sertraline-Associated Insomnia in Depressed Patients.

Neuropsychiatr Dis Treat 2020 4;16:1121-1128. Epub 2020 May 4.

Department of Pharmacology and Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Selective serotonin reuptake inhibitors (SSRIs) are considered as first-line drugs for treating depressive disorders. Among the adverse effects reported with sertraline is sleep disturbances; however, the etiology lying beneath is obscure. Orexin, the most recently discovered neurotransmitter, is involved in the sleep cycle. Read More

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http://dx.doi.org/10.2147/NDT.S250141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210038PMC

New Medications for Neuropsychiatric Disorders.

Psychiatr Clin North Am 2020 Jun 8;43(2):399-413. Epub 2020 Apr 8.

Department of Psychiatry and Neuroscience, University of California Riverside School of Medicine, 14350-1 Meridian Parkway, Riverside, CA 92518, USA; Neuroscience Education Institute, 1917 Palomar Oaks Way, Suite 200, Carlsbad, CA 92008, USA; Department of Psychiatry, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA.

This article seeks to summarize the mechanisms of action, clinical trials, and FDA approval status of several psychiatric medications that are either newly available or in the FDA approval process. This article highlights medications that demonstrate novel mechanisms of action, examines nonpsychiatric medications that are being used to augment existing psychiatric treatments, and elucidates treatments for illnesses that have not previously received FDA indications. Read More

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http://dx.doi.org/10.1016/j.psc.2020.02.008DOI Listing

Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis.

Brain Behav Immun 2020 May 8. Epub 2020 May 8.

National and Kapodistrian University of Athens, Athens, Greece; Pulmonary and Respiratory Failure Department, First ICU, Evaggelismos Hospital. Athens, Greece.

Background: COVID-19 pandemic has the potential to significantly affect the mental health of healthcare workers (HCWs), who stand in the frontline of this crisis. It is, therefore, an immediate priority to monitor rates of mood, sleep and other mental health issues in order to understand mediating factors and inform tailored interventions. The aim of this review is to synthesize and analyze existing evidence on the prevalence of depression, anxiety and insomnia among HCWs during the Covid-19 outbreak. Read More

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http://dx.doi.org/10.1016/j.bbi.2020.05.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206431PMC

Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic.

Lancet Psychiatry 2020 May 18. Epub 2020 May 18.

UCL Institute of Mental Health, University College London, London, UK.

Background: Before the COVID-19 pandemic, coronaviruses caused two noteworthy outbreaks: severe acute respiratory syndrome (SARS), starting in 2002, and Middle East respiratory syndrome (MERS), starting in 2012. We aimed to assess the psychiatric and neuropsychiatric presentations of SARS, MERS, and COVID-19.

Methods: In this systematic review and meta-analysis, MEDLINE, Embase, PsycINFO, and the Cumulative Index to Nursing and Allied Health Literature databases (from their inception until March 18, 2020), and medRxiv, bioRxiv, and PsyArXiv (between Jan 1, 2020, and April 10, 2020) were searched by two independent researchers for all English-language studies or preprints reporting data on the psychiatric and neuropsychiatric presentations of individuals with suspected or laboratory-confirmed coronavirus infection (SARS coronavirus, MERS coronavirus, or SARS coronavirus 2). Read More

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http://dx.doi.org/10.1016/S2215-0366(20)30203-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234781PMC

Characterizing motivations for cannabis use in a cohort of people who use illicit drugs: A latent class analysis.

PLoS One 2020 21;15(5):e0233463. Epub 2020 May 21.

British Columbia Centre on Substance Use, Vancouver, BC, Canada.

Background: Cannabis use is common among marginalized people who use illicit drugs (PWUD) but reasons for use remain poorly investigated. We sought to explore how different intentions for cannabis use relate to social, structural, and behavioural factors among PWUD in Vancouver, Canada.

Methods: We used data from cannabis-using participants in two community-recruited prospective cohort studies of PWUD. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233463PLOS

Variations of Oral Microbiome in Chronic Insomnia Patients with Different Tongue Features.

Am J Chin Med 2020 May 21:1-22. Epub 2020 May 21.

Chinese Medicine School, Beijing University of Chinese Medicine, Beijing 100029, P. R. China.

Chronic insomnia is a disease which brings intense mental pain and disturbing complications to patients worldwide. The oral microbiome exhibits a mechanistic influence on human health. Therefore, it is crucial to understand the oral microbial diversity in insomnia. Read More

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http://dx.doi.org/10.1142/S0192415X20500445DOI Listing

Insomnia during the COVID-19 pandemic in a Greek population.

Psychiatry Res 2020 May 12;289:113076. Epub 2020 May 12.

1st Department of Psychiatry, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Insomnia is a major health issue associated with great psychological burden. Research of insomnia during a pandemic crisis is limited. The aim of the present study was to explore sleep difficulties during the COVID-19 pandemic in a Greek population. Read More

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http://dx.doi.org/10.1016/j.psychres.2020.113076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217074PMC

Cannabis and Complex Posttraumatic Stress Disorder: A Narrative Review With Considerations of Benefits and Harms.

J Nerv Ment Dis 2020 May 19. Epub 2020 May 19.

Department of Psychiatry, University of Colorado School of Medicine, Aurora, Colorado.

Despite substantial controversies concerning patients' reports of benefits from cannabis for posttraumatic stress disorder (PTSD) and inconsistent research findings regarding its efficacy and adverse risks, some states have already recognized PTSD as a qualifying condition for medical cannabis. Consequently, medical cannabis can also be provided for patients with complex PTSD who experience additional posttraumatic symptoms of affective dysregulation, negative perception of the self, and difficulties in relationships due to a history of repetitive trauma. In this article, we explore cannabis use in relation to benefits versus harms that might occur relative to specific complex PTSD symptoms and comorbidities. Read More

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http://dx.doi.org/10.1097/NMD.0000000000001172DOI Listing

[Sleep in the intensive care unit].

Somnologie (Berl) 2020 9;24(1):16-20. Epub 2020 Mar 9.

Klinik für Pneumologie, VAMED Klinik Hagen Ambrock, Ambrocker Weg 60, 58091 Hagen, Deutschland.

Many patients are treated in intensive care units daily, often over a long period of time. Sleep plays a role that should not be underestimated for these patients. Sleep disorders are a relevant problem for intensive care patients and lead to a higher prevalence of delirium in these patients and thus to a longer length of stay in the intensive care unit and to a higher mortality. Read More

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http://dx.doi.org/10.1007/s11818-020-00246-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222097PMC

Cyclosporine-A-Based Immunosuppressive Therapy-Induced Neurotoxicity: A Case Report.

Open Access Emerg Med 2020 28;12:93-97. Epub 2020 Apr 28.

Department of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Cyclosporine-A (CsA) and mycophenolate mofetil are immunosuppressive drugs used for the prevention of transplant rejection. Various clinical studies have been performed on different forms of CsA neurotoxicity, including tremor, paresthesia, confusion, ataxia, neuralgia, hemiplegia, occipital seizures, and transient cortical blindness. Mycophenolate is associated with several neurological side effects including headache, insomnia, dizziness, depression, confusion, hypertonia, and paresthesia. Read More

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http://dx.doi.org/10.2147/OAEM.S241501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197938PMC

Dietary sources of melatonin and benefits from production of high melatonin pasteurized milk.

J Food Sci Technol 2020 Jun 10;57(6):2026-2037. Epub 2020 Jan 10.

1Research Unit of Nutrition for Health, Department of Food Technology and Nutrition, Faculty of Technology, Mahasarakham University, Kuntarawichai, Maha Sarakham 44150 Thailand.

Melatonin is a neurohormone that regulates circadian rhythms in the human body. It can also be taken to alleviate insomnia and sleep disorders. Pasteurized milk is a good source of nutrients and some bioactive compounds. Read More

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http://dx.doi.org/10.1007/s13197-020-04236-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230083PMC

Subjective-objective sleep discrepancy in patients with insomnia during and after cognitive behavioural therapy: An actigraphy study.

J Sleep Res 2020 May 20:e13064. Epub 2020 May 20.

National Institute of Mental Health, Klecany, Czech Republic.

Although patients with insomnia often show a discrepancy between self-reported and objective sleep parameters, the role of and change in this phenomenon during treatment remain unclear. The present study aimed to assess the effect of cognitive behavioural therapy for insomnia on subjective and objective sleep discrepancy of total sleep time, sleep-onset latency and wake after sleep onset. The total sleep time discrepancy was also assessed across the entire therapy. Read More

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http://dx.doi.org/10.1111/jsr.13064DOI Listing

Early Childhood Sleep Intervention in Urban Primary Care: Clinician and Caregiver Perspectives.

J Pediatr Psychol 2020 May 20. Epub 2020 May 20.

Perelman School of Medicine, University of Pennsylvania.

Background: Despite significant income-related disparities in pediatric sleep, few early childhood sleep interventions have been tailored for or tested with families of lower socio-economic status (SES). This qualitative study assessed caregiver and clinician perspectives to inform adaptation and implementation of evidence-based behavioral sleep interventions in urban primary care with families who are predominantly of lower SES.

Methods: Semi-structured interviews were conducted with (a) 23 caregivers (96% mothers; 83% Black; 65% ≤125% U. Read More

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http://dx.doi.org/10.1093/jpepsy/jsaa024DOI Listing

Cannabidiol (CBD) and Δ-tetrahydrocannabinol (THC) for chronic insomnia disorder ('CANSLEEP' trial): protocol for a randomised, placebo-controlled, double-blinded, proof-of-concept trial.

BMJ Open 2020 May 18;10(5):e034421. Epub 2020 May 18.

Woolcock Institute of Medical Research, Centre for Sleep and Chronobiology, Sydney, New South Wales, Australia

Introduction: Insomnia is a highly prevalent and costly condition that is associated with increased health risks and healthcare utilisation. Anecdotally, cannabis use is frequently reported by consumers to promote sleep. However, there is limited research on the effects of cannabis on sleep and daytime function in people with insomnia disorder using objective measures. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-034421DOI Listing

: a source for anti-Alzheimer's disease drugs.

Pharm Biol 2020 Dec;58(1):410-416

Ningxia Medical University Pharmacy College, Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Research Center of Modern Hui Medicine Engineering and Technology, Yinchuan, P. R. China.

Alzheimer's disease (AD) is a chronic neurodegenerative disease that originates from central nervous system lesions or recessions. Current estimates suggest that this disease affects over 35 million people worldwide. However, lacking effective drugs is the biggest handicap in treating AD. Read More

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http://dx.doi.org/10.1080/13880209.2020.1758732DOI Listing
December 2020

Low-Intensity Cognitive Behavioral Therapy for Insomnia as the Entry of the Stepped-Care Model in the Community: A Randomized Controlled Trial.

Behav Sleep Med 2020 May 20:1-17. Epub 2020 May 20.

Department of Psychiatry, Queen Mary Hospital, Hong Kong, Hong Kong SAR.

: Diverse low-intensity interventions are available as the entry points in the stepped-care model for insomnia. The study aims to compare a single-session cognitive behavioral therapy for insomnia (CBTI) workshop, self-help CBTI and sleep hygiene education (SHE) workshop among adults with insomnia in the community, in terms of insomnia severity, anxiety and depressive symptoms, the quality of life, treatment adherence and credibility.: Two-hundred-and-ten Hong Kong adults with DSM-5 defined insomnia disorder for at least one month were recruited in the community. Read More

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http://dx.doi.org/10.1080/15402002.2020.1764000DOI Listing

Three steps to flatten the mental health need curve amid the COVID-19 pandemic.

Depress Anxiety 2020 05;37(5):405-406

Department of Psychiatry, Community Psychiatry Program for Research in Implementation and Dissemination of Evidence Based Treatments (Community Psychiatry PRIDE), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/da.23031DOI Listing

Treating Insomnia during the COVID-19 Pandemic: Observations and Perspectives from a Behavioral Sleep Medicine Clinic.

Behav Sleep Med 2020 May 19:1-3. Epub 2020 May 19.

Sleep Health & Insomnia Program, Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1080/15402002.2020.1765781DOI Listing

Pilot Trial of a Noninvasive Closed-Loop Neurotechnology for Stress-Related Symptoms in Law Enforcement: Improvements in Self-Reported Symptoms and Autonomic Function.

Glob Adv Health Med 2020 7;9:2164956120923288. Epub 2020 May 7.

Department of Neurology, Wake Forest School of Medicine, Winston-Salem, North Carolina.

Background: Law enforcement officers have decreased life expectancy, attributed to work-related exposure to traumatic stress and circadian disruption. Autonomic dysregulation is reported with traumatic stress and chronic insomnia.

Objective: We explore potential benefits for reduced symptoms related to stress and insomnia and improved autonomic function associated with open label use of high-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM®), in a cohort of sworn law enforcement personnel. Read More

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http://dx.doi.org/10.1177/2164956120923288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218336PMC