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    3493 results match your criteria Insect Repellents

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    Micromorphological and histochemical attributes of flowers and floral reward in Linaria vulgaris (Plantaginaceae).
    Protoplasma 2018 Jun 3. Epub 2018 Jun 3.
    Department of Botany, University of Life Sciences in Lublin, 15 Akademicka St., 20-950, Lublin, Poland.
    The self-incompatible flowers of Linaria vulgaris have developed a range of mechanisms for attraction of insect visitors/pollinators and deterrence of ineffective pollinators and herbivores. These adaptive traits include the flower size and symmetry, the presence of a spur as a "secondary nectar presenter," olfactory (secondary metabolites) and sensual (scent, flower color, nectar guide-contrasting palate) signals, and floral rewards, i.e. Read More

    Retrospective analysis of Bluetongue farm risk profile definition, based on biology, farm management practices and climatic data.
    Prev Vet Med 2018 Jul 12;155:75-85. Epub 2018 Apr 12.
    Istituto Zooprofilattico Sperimentale della Sardegna "G. Pegreffi" - Centro di Sorveglianza Epidemiologica, Via XX Settembre n°9, 09125, Cagliari, CA, Italy.
    Bluetongue (BT) is a vector-borne disease transmitted by species of Culicoides midges (Diptera: Ceratopogonidae). Many studies have contributed to clarifying various aspects of its aetiology, epidemiology and vector dynamic; however, BT remains a disease of epidemiological and economic importance that affects ruminants worldwide. Since 2000, the Sardinia region has been the most affected area of the Mediterranean basin. Read More

    Stratum corneum substantivity: drug development implications.
    Arch Dermatol Res 2018 May 11. Epub 2018 May 11.
    Department of Dermatology, School of Medicine, University of California, San Francisco, 90 Medical Center Way, Box 0989, Surge Building, Room 110, San Francisco, CA, 94143, USA.
    There are at least 15 factors that influence the ability of chemicals to penetrate the skin. Substantivity is yet another factor and allows penetrants to remain on and in skin for many days. As many skin pathologies involve stratum corneum and require multiple dosing of topicals, understanding substantivity mechanisms may provide insight for topical dosing strategies. Read More

    Identification of novel bioinspired synthetic mosquito repellents by combined ligand-based screening and OBP-structure-based molecular docking.
    Insect Biochem Mol Biol 2018 Jul 8;98:48-61. Epub 2018 May 8.
    Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece. Electronic address:
    In this work we report a fast and efficient virtual screening protocol for discovery of novel bioinspired synthetic mosquito repellents with lower volatility and, in all likelihood, increased protection time as compared with their plant-derived parental compounds. Our screening protocol comprises two filtering steps. The first filter is based on the shape and chemical similarity to known plant-derived repellents, whereas the second filter is based on the predicted similarity of the ligand's binding mode to the Anopheles gambiae odorant binding protein (AgamOBP1) relative to that of DEET and Icaridin to the same OBP. Read More

    Ethnobotanical survey of plants used as repellents against housefly, Musca domestica L. (Diptera: Muscidae) in Budondo Subcounty, Jinja District, Uganda.
    J Ethnobiol Ethnomed 2018 May 10;14(1):35. Epub 2018 May 10.
    Department of Biology, Faculty of Science, Gulu University, P.O. Box 166, Gulu, Uganda.
    Background: The housefly, Musca domestica L., is a major public health and domestic pest that spoils food and causes irritation and is a vector of many infectious disease pathogens of medical and veterinary importance. Currently, its control relies largely on chemical pesticides. Read More

    Prospects for management of whitefly using plant semiochemicals, compared with related pests.
    Pest Manag Sci 2018 May 2. Epub 2018 May 2.
    Biointeractions and Crop Protection Department, Rothamsted Research, Harpenden, UK.
    Whitefly (Hemiptera: Sternorrhyncha: Aleyrodidae) pests, including the tobacco whitefly, Bemisia tabaci, and the greenhouse whitefly, Trialeurodes vaporariorum, are important economically in agriculture. Whiteflies are controlled mainly by synthetic insecticides but resistance to these is evolving rapidly. A semiochemical-based management strategy could provide an alternative to the use of insecticides, by exploiting natural volatile signalling processes to manipulate insect behaviour. Read More

    Terpenes associated with resistance against the gall wasp, Leptocybe invasa, in Eucalyptus grandis.
    Plant Cell Environ 2018 Apr 30. Epub 2018 Apr 30.
    Research School of Biology, Australian National University, 46 Sullivans Creek Road, Canberra, 2601, Australian Capital Territory, Australia.
    Leptocybe invasa is an insect pest causing gall formation on oviposited shoot tips and leaves of Eucalyptus trees leading to leaf deformation, stunting, and death in severe cases. We previously observed different constitutive and induced terpenes, plant specialized metabolites that may act as attractants or repellents to insects, in a resistant and susceptible clone of Eucalyptus challenged with L. invasa. Read More

    Inhibitory Effects of Semiochemicals on the Attraction of an Ambrosia Beetle Euwallacea nr. fornicatus to Quercivorol.
    J Chem Ecol 2018 Jun 17;44(6):565-575. Epub 2018 Apr 17.
    Institute of Plant Protection, Agricultural Research Organization, Volcani Center, Rishon LeZion, Israel.
    The Euwallacea fornicatus (Eichhoff) species complex includes the polyphagous shot hole borer (PSHB), an ambrosia beetle infesting avocado limbs, Persea americana Mill. Synthetic quercivorol, a monoterpene alcohol, is known to attract females (males are flightless) over a range of release rates spanning three orders of magnitude. The upper release dose was extended 10-fold using sticky traps baited with quercivorol released at 1× (0. Read More

    Safety Evaluation of Various Vector Repellents in Combination with Deltamethrin in Wistar Rats.
    J Pharm Bioallied Sci 2018 Jan-Mar;10(1):21-28
    Department of Research and Development, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.
    Background: Vector repellents are used globally to avoid insect bites and control transmission of diseases. It is important to ensure safety levels of these compounds, although they are noxious to insects. Vector repellents when used in combination are known to bring additional benefits in getting rid of the harmful insects. Read More

    Odorant-binding protein-based identification of natural spatial repellents for the African malaria mosquito Anopheles gambiae.
    Insect Biochem Mol Biol 2018 May 12;96:36-50. Epub 2018 Apr 12.
    Institute of Biology, Faculty of Science, University of Neuchâtel, rue Emile-Argand 11, 2000 Neuchâtel, Switzerland. Electronic address:
    There is increasing interest in the development of effective mosquito repellents of natural origin to reduce transmission of diseases such as malaria and yellow fever. To achieve this we have employed an in vitro competition assay involving odorant-binding proteins (OBPs) of the malaria mosquito, Anopheles gambiae, with a predominantly female expression bias to identify plant essential oils (EOs) containing bioactive compounds that target mosquito olfactory function. EOs and their fractions capable of binding to such OBPs displayed repellence against female mosquitoes in a laboratory repellent assay. Read More

    New insights on repellent recognition by Anopheles gambiae odorant-binding protein 1.
    PLoS One 2018 3;13(4):e0194724. Epub 2018 Apr 3.
    School of Life, Health and Chemical Sciences, Open University, Milton Keynes, United Kingdom.
    It is generally recognized that insect odorant binding proteins (OBPs) mediate the solubilisation and transport of hydrophobic odorant molecules and contribute to the sensitivity of the insect olfactory system. However, the exact mechanism by which OBPs deliver odorants to olfactory receptors and their role, if any, as selectivity filters for specific odorants, are still a matter of debate. In the case of Anopheles gambiae, recent studies indicate that ligand discrimination is effected through the formation of heterodimers such as AgamOBP1 and AgamOBP4 (odorant binding proteins 1 and 4 from Anopheles gambiae). Read More

    The paediatric traveller.
    Int Marit Health 2018 ;69(1):70-74
    Department of Epidemiology and Tropical Medicine in Gdynia, Military Institute of Medicine, Poland.
    International travel with children, which is the opportunity for the family to see the world together, has become commonplace. If you are travelling with children the journey needs to be carefully planned, especially in cases of visiting a region with harsh environment or poor sanitation. It is particularly important in terms of thermoregulation (hot climate) and the immune system (protection against pathogens causing infectious and invasive diseases) as these are not fully developed in small children. Read More

    Prevalence and spatial distribution of Ixodid tick populations in the forest fringes of Western Ghats reported with human cases of Kyasanur forest disease and monkey deaths in South India.
    Exp Appl Acarol 2018 May 28;75(1):135-142. Epub 2018 Mar 28.
    Vector Control Research Centre (Indian Council of Medical Research, Ministry of Health and Family Welfare Government of India), Indira Nagar, Pondicherry, 605 006, India.
    Kyasanur forest disease (KFD) is a major tick-borne viral haemorrhagic fever caused by KFD virus (KFDV) (Flaviviridae). The disease was reported to be confined to five districts of Karnataka state India until 2011. During 2012-2016, emergence of KFD has been reported in newer areas of Karnataka and adjoining states. Read More

    Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells.
    Toxicol Lett 2018 Jun 20;290:55-61. Epub 2018 Mar 20.
    Reproductive Toxicology Branch, Toxicity Assessment Division, National Health and Environmental Effects Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA, USA. Electronic address:
    In utero exposure to certain phthalate esters results in testicular toxicity, characterized at the tissue level by induction of multinucleated germ cells (MNGs) in rat, mouse, and human fetal testis. Phthalate exposures also result in a decrease in testicular testosterone in rats. The anti-androgenic effects of phthalates have been more thoroughly quantified than testicular pathology due to the significant time requirement associated with manual counting of MNGs on histological sections. Read More

    Pest Management Strategies Against the Coffee Berry Borer (Coleoptera: Curculionidae: Scolytinae).
    J Agric Food Chem 2018 May 22;66(21):5275-5280. Epub 2018 Mar 22.
    El Colegio de la Frontera Sur (ECOSUR) , Carretera Antiguo Aeropuerto km 2.5 , Tapachula , 30700 Chiapas México.
    Coffee ( Coffea arabica and C. canephora) is one of the most widely traded agricultural commodities and the main cash crop in ∼80 tropical countries. Among the factors that limit coffee production, the coffee berry borer, Hypothenemus hampei (Ferrari) has been considered the main insect pest, causing losses of over U. Read More

    Synthesis, Bioassays and Field Evaluation of Hydroxycoumarins and their Alkyl Derivatives as Repellents or Kairomones for Aedes albopictus Skuse (Diptera: Culicidae).
    J Chem Ecol 2018 Mar 10;44(3):299-311. Epub 2018 Mar 10.
    Laboratory International Associates, University of Antananarivo-University of Lyon 1, PO Box 906, Antananarivo, Madagascar.
    In recent years, a significant increase in mosquito-borne diseases has been recorded worldwide. Faced with the limitations of existing methods for controlling the vector mosquito population, the development of attractants to bait traps and repellents to limit host-vector contacts could be promising and environmentally-friendly control strategies. The purpose of this study was to evaluate the effect of hydroxycoumarins and their alkyls derivatives against Aedes albopictus, the main vector of several arboviruses. Read More

    On-line solid phase extraction-liquid chromatography-tandem mass spectrometry for insect repellent residue analysis in surface waters using atmospheric pressure photoionization.
    J Chromatogr A 2018 Apr 21;1544:33-40. Epub 2018 Feb 21.
    Dept. of Environmental Chemistry, IDAEA-CSIC, C/Jordi Girona 18-26, 08034, Barcelona, Spain; Catalan Institute for Water Research (ICRA), Parc Científic i Tecnològic de la Universitat de Girona, C/Emili Grahit, 101 Edifici H2O, 17003, Girona, Spain.
    Insect repellents (IRs) are a group of organic chemicals whose function is to prevent the ability of insects of landing in a surface. These compounds have been found in the environment and may pose a risk to non-target organisms. In this study, an on-line solid phase extraction - high performance liquid chromatography-tandem mass spectrometry multiresidue method was developed using an atmospheric photoionization source (SPE-HPLC-(APPI)-MS/MS). Read More

    Botanical essential oils and uses as mosquitocides and repellents against dengue.
    Environ Int 2018 Apr 13;113:214-230. Epub 2018 Feb 13.
    United States Department of Agriculture, Agricultural Research Service, U.S. Horticultural Research Laboratory, 2001 South Rock Road, Fort Pierce, FL 34945, USA.
    Plants naturally produce bioactive compounds along with many secondary metabolites which serve as defensive chemical against herbivorers including insect pests. One group of these phytochemicals are the 'Essential Oils' (EO's), which possess an extensive range of biological activity especially insecticidal and insect repellents. This review provides a comprehensive viewpoint on potential modes of action of biosafety plant derived Essential Oils (EO's) along with their principal chemical derivatives against larvae and adult mosquito vectors of dengue virus. Read More

    Urinary concentrations of benzophenone-type ultra violet light filters and reproductive parameters in young men.
    Int J Hyg Environ Health 2018 Apr 9;221(3):531-540. Epub 2018 Feb 9.
    Division of Preventive Medicine and Public Health, Department of Public Health Sciences, University of Murcia School of Medicine, 30100 Murcia, Spain; Health Research Methodology Group, Biomedical Research Institute of Murcia (IMIB-Arrixaca), 30120 El Palmar, Murcia, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain; Department of Preventive Medicine, "Virgen de la Arrixaca" University Clinical Hospital, 30120 El Palmar, Murcia, Spain.
    Background: Benzophenone (BP)-type ultraviolet (UV) light filters are chemicals frequently added to personal care products, insect repellents, sunscreens, and beverage and food packaging to diminish the harmful effects of UV sunlight on human skin or foodstuffs. BP-type UV filters have shown negative effects on male reproduction function in in vitro and animal models, but human epidemiologic studies are limited. The goal of this study was to examine associations between urinary concentrations of BP-type UV filters and semen quality and reproductive hormone levels. Read More

    A natural agonist of mosquito TRPA1 from the medicinal plant Cinnamosma fragrans that is toxic, antifeedant, and repellent to the yellow fever mosquito Aedes aegypti.
    PLoS Negl Trop Dis 2018 02 9;12(2):e0006265. Epub 2018 Feb 9.
    Department of Entomology, The Ohio State University, Ohio Agricultural Research and Development Center, Wooster, Ohio, United States of America.
    Plants produce various secondary metabolites that offer a potential source of novel insecticides and repellents for the control of mosquito vectors. Plants of the genus Cinnamosma are endemic to, and widely-distributed throughout, the island of Madagascar. The barks of these species are commonly used in traditional medicines for treating a wide range of maladies. Read More

    Deltamethrin-resistant German Cockroaches Are Less Sensitive to the Insect Repellents DEET and IR3535 than Non-resistant Individuals.
    J Econ Entomol 2018 Apr;111(2):836-843
    UNIDEF-CITEDEF-CONICET-CIPEIN, J.B. de La Salle,Villa Martelli, Buenos Aires, Argentina.
    The German cockroach, Blattella germanica (L.) (Blattodea: Blattellidae), is a serious worldwide pest with a considerable economical and sanitary impact. It is mainly controlled by the application of synthetic insecticides, but repeated use of these substances has promoted the appearance of resistance in cockroach populations throughout the world. Read More

    Trends in insect repellent formulations: A review.
    Int J Pharm 2018 Mar 3;539(1-2):190-209. Epub 2018 Feb 3.
    Federal University of Rio de Janeiro, Faculty of Pharmacy, Department of Medicines, Laboratório de Desenvolvimento Galênico (LADEG), Carlos Chagas Filho Avenue, Ilha do Fundão, Rio de Janeiro 21941-590, Brazil.
    The use of natural and synthetic repellents, marketed in different pharmaceutical forms, is growing in the world due to the emerging vector-borne viral diseases as Dengue, Zika, Chikungunya, Yellow Fever and Malaria. The choice of the ideal formulation will depend on a series of factors to be analyzed: type of repellent active (natural or synthetic), pharmaceutical forms (spray, lotion, cream, gel), action time duration (short or long), environment of exposure and the user (adult, pregnant women, children, newborn). The most used repellents are DEET, IR3535 (Ethyl Butylacetylaminopropionate) (EB), Icaridin (Picaridin) and essential oils, each of them presenting advantages and disadvantages. Read More

    Mosquito repellents for malaria prevention.
    Cochrane Database Syst Rev 2018 02 6;2:CD011595. Epub 2018 Feb 6.
    Public Health and Epidemiology, Swiss Tropical and Public Health Institute, Socinstrasse 57, Basel, Switzerland, CH-4051.
    Background: Malaria is an important cause of illness and death across endemic regions. Considerable success against malaria has been achieved within the past decade mainly through long-lasting insecticide-treated nets (LLINs). However, elimination of the disease is proving difficult as current control methods do not protect against mosquitoes biting outdoors and when people are active. Read More

    Sustainable manufacture of insect repellents derived from Nepeta cataria.
    Sci Rep 2018 Feb 2;8(1):2235. Epub 2018 Feb 2.
    Département de Génie Chimique, École Polytechnique de Montréal, 2900, boul. Édouard-Montpetit, H3C 3A7, Montréal, QC, Canada.
    Malaria devastates sub-Saharan Africa; the World Health Organization (WHO) estimates that 212 million people contract malaria annually and that the plasmodium virus will kill 419 000 in 2017. The disease affects rural populations who have the least economic means to fight it. Impregnated mosquito nets have reduced the mortality rate but the Anopheles mosquitoes are changing their feeding patterns and have become more active at dusk and early morning rather than after 22h00 as an adaptation to the nets. Read More

    Determining Exposure Factors of Anti-Fogging, Dye, Disinfectant, Repellent, and Preservative Products in Korea.
    Int J Environ Res Public Health 2018 Jan 30;15(2). Epub 2018 Jan 30.
    Division of Risk Assessment, National Institute of Environmental Research, Hwangyeong-ro 42, Seo-gu, Incheon 22689, Korea.
    Reliable exposure factors are essential to determine health risks posed by chemicals in consumer products. We analyzed five risk-concerned product categories (anti-fogging, dye, disinfectant, repellent, and preservative products) for 13 products (three car anti-fogging products, a lens anti-fogging product, two car dye products, two drain disinfectants, an air conditioner disinfectant, a chlorine-based disinfectant, a fabric repellent, an insect repellent for food, and a wood preservative) considered to be of high risk in order to determine exposure factors via web surveys and estimation of amount of product. Among the 3000 participants (1482 (49%) men) aged ≥19 years, drain disinfectants were used most frequently (38. Read More

    Zein Nanoparticles as Eco-Friendly Carrier Systems for Botanical Repellents Aiming Sustainable Agriculture.
    J Agric Food Chem 2018 Feb 1;66(6):1330-1340. Epub 2018 Feb 1.
    Institute of Science and Technology, São Paulo State University (UNESP) , Sorocaba, São Paulo 18087-180, Brazil.
    Botanical repellents represent one of the main ways of reducing the use of synthetic pesticides and the contamination of soil and hydric resources. However, the poor stability and rapid degradation of these compounds in the environment hinder their effective application in the field. Zein nanoparticles can be used as eco-friendly carrier systems to protect these substances against premature degradation, provide desirable release characteristics, and reduce toxicity in the environment and to humans. Read More

    Evidence for activation of nitenpyram by a mitochondrial cytochrome P450 in Drosophila melanogaster.
    Pest Manag Sci 2018 Jul 26;74(7):1616-1622. Epub 2018 Feb 26.
    Department of Genetics and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria, Australia.
    Background: Nitenpyram is a member of the economically important neonicotinoid class of insecticides. The in vivo metabolism of nitenpyram is not well characterised, but cytochrome P450 activity is the major mechanism of resistance to neonicotinoids identified in insect pests, and P450s metabolise other neonicotinoids including imidacloprid.

    Results: Here, we used the GAL4-UAS targeted expression system to direct RNA interference (RNAi) against the cytochrome P450 redox partners to interrupt P450 functions in specific tissues in Drosophila melanogaster. Read More

    A Pilot Qualitative Investigation of Stakeholders' Experiences and Opinions of Equine Insect Bite Hypersensitivity in England.
    Vet Sci 2018 Jan 9;5(1). Epub 2018 Jan 9.
    Department of Animal Production, Welfare and Veterinary Sciences, Harper Adams University, Newport, Shropshire TF10 8NB, UK.
    Equine insect bite hypersensitivity (IBH), commonly known as sweet itch or summer eczema, is a frustrating recurrent skin disease in the equine industry involving an immune reaction to the bites of spp. midges. To investigate the impact of IBH in the field, an exploratory pilot study was conducted with equine stakeholders in one region of central England. Read More

    DEET as a feeding deterrent.
    PLoS One 2017 14;12(12):e0189243. Epub 2017 Dec 14.
    Department of Molecular and Cellular Biology, University of California Davis, Davis, CA, United States of America.
    The insect repellent N,N-diethyl-3-methylbenzamide (DEET), is a multimodal compound that acts as a spatial repellent as well as an irritant (contact repellent), thus being perceived by the insect's olfactory and gustatory systems as an odorant and a tastant, respectively. Soon after DEET was developed, almost 6 decades ago, it was reported that it reduced mosquito feeding on blood mixed with this repellent. It is now known that the mosquito proboscis senses contact repellents with the tips (labella) of the labium, which remain in direct contact with the outer layers of the skin, while the stylets, including the feeding deterrent sensor (labrum), penetrate the skin. Read More

    Neurotoxic Effects of Linalool and β-Pinene on Tribolium castaneum Herbst.
    Molecules 2017 11 24;22(12). Epub 2017 Nov 24.
    Environmental and Computational Chemistry Group, Zaragocilla Campus, School of Pharmaceutical Sciences, University of Cartagena, Cartagena 130016, Bolivar, Colombia
    Effective, ethical pest control requires the use of chemicals that are highly specific, safe, and ecofriendly. Linalool and β-pinene occur naturally as major constituents of the essential oils of many plant species distributed throughout the world, and thus meet these requirements. These monoterpenes were tested as repellents against , using the area preference method, after four hours of exposure and the effect transcriptional of genes associated with neurotransmission. Read More

    Essential oils and their components as an alternative in the control of mosquito vectors of disease.
    Biomedica 2017 Mar 29;37(0):224-243. Epub 2017 Mar 29.
    Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México, México.
    More than half of the human population is exposed to mosquito-borne infections. Climate change and the emergence of strains resistant to traditionally used insecticides have motivated the search of new agents for mosquito population control. Essential oils have been effective repellents and larvicidal agents. Read More

    Characterizing pollutant emissions from mosquito repellents incenses and implications in risk assessment of human health.
    Chemosphere 2018 Jan 22;191:962-970. Epub 2017 Oct 22.
    Shanghai Research Institute of Building Sciences Group, Shanghai, 201108, China. Electronic address:
    Mosquito-repellent incense is one of the most popular products used for dispelling mosquitos during summer in China. It releases large amounts of particulate and gaseous pollutants which constitute a potential hazard to human health. We conducted chamber experiment to characterize major pollutants from three types of mosquito-repellent incenses, further assessed the size-fractionated deposition in human respiratory system, and evaluated the indoor removing efficiency by fresh air. Read More

    Shifting the paradigm in Dirofilaria immitis prevention: blocking transmission from mosquitoes to dogs using repellents/insecticides and macrocyclic lactone prevention as part of a multimodal approach.
    Parasit Vectors 2017 Nov 9;10(Suppl 2):525. Epub 2017 Nov 9.
    TRS Labs, Inc., 215 Paradise Boulevard, Athens, GA, 30607, USA.
    Background: This study assessed the influence of a topical ectoparasiticide (dinotefuran-permethrin-pyriproxyfen, DPP, Vectra® 3D, Ceva Animal Health) combined with a macrocyclic lactone (milbemycin oxime, MBO, Interceptor®, Virbac) on transmission of heartworm L3 from mosquitoes to dogs and subsequent development of worms in treated dogs exposed to infected mosquitoes.

    Methods: Thirty-two beagle dogs were allocated to four groups of eight: Group 1, untreated controls; Group 2, treated topically with DPP on Day 0; Group 3, treated orally with MBO on Day 51; and Group 4, treated with DPP on Day 0 and MBO on Day 51. Dogs were exposed under sedation for 1 h to Dirofilaria immitis (JYD-34)-infected Aedes aegypti on Days 21 and 28. Read More

    Toxic effects of Solanum xanthocarpum Sch &Wendle against Helicoverpa armigera (Hub.), Culex quinquefasciatus (Say.) and Eisenia fetida (Savigny, 1826).
    Environ Sci Pollut Res Int 2018 Jan 15;25(3):2774-2782. Epub 2017 Nov 15.
    Entomology Research Institute, Loyola College, Chennai, 600 034, Tamil Nadu, India.
    Many commercially available agro and household chemicals are used as pesticides, repellents, and growth inhibitors against insect pests. The repeated uses of these chemicals against insect pests have caused the development of resistance in them; they also cause ill effects on nontarget organisms. The present study was aimed to evaluate the antifeedant, larvicidal, pupicidal, and biochemical effects of the solvent extracts of Solanum xanthocarpum against third instar larvae of Helicoverpa armigera. Read More

    Development and validation of modified QuEChERS method coupled with LC-MS/MS for simultaneous determination of cymiazole, fipronil, coumaphos, fluvalinate, amitraz, and its metabolite in various types of honey and royal jelly.
    J Chromatogr B Analyt Technol Biomed Life Sci 2018 Jan 8;1072:60-69. Epub 2017 Nov 8.
    Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Konkuk University, Seoul 143-701, Republic of Korea. Electronic address:
    Over the past few decades, honey products have been polluted by different contaminants, such as pesticides, which are widely applied in agriculture. In this work, a modified EN - quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction method was developed for the simultaneous quantification of pesticide residues, including cymiazole, fipronil, coumaphos, fluvalinate, amitraz, and its metabolite 2,4-dimethylaniline (2,4-DMA), in four types of honey (acacia, wild, chestnut, and manuka) and royal jelly. Samples were buffered with 0. Read More

    Seasonal Terpene Variation in Needles of Pinus radiata (Pinales: Pinaceae) Trees Attacked by Tomicus piniperda (Coleoptera: Scolytinae) and the Effect of Limonene on Beetle Aggregation.
    J Insect Sci 2017 Sep;17(5)
    Université catholique de Louvain, ELIB, Earth and Life Institute, Croix du Sud 4-5, 1348 Louvain, Belgium.
    Concentrations of four monoterpenes were determined in needles of Pinus radiata (D.Don) (Pinales: Pinaceae) trees that were attacked or nonattacked by Tomicus piniperda (L.) (Coleoptera: Scolytinae). Read More

    "Gold" Pressed Essential Oil: An Essay on the Volatile Fragment from Juice Industry By-Products Chemistry and Bioactivity.
    Biomed Res Int 2017 4;2017:2761461. Epub 2017 Oct 4.
    Department of Nutritional Physiology and Feeding, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece.
    Present essay explores the potentials of juice industry's by-products as alternative bioactive natural products resources. Four crude Cold Pressed Essential Oils (CPEOs), derived from orange, lemon, grapefruit, and mandarin, were studied. All CPEOs were subjected to water distillation, in order to obtain the volatile fragment, which was further fractionated with respect to distillation period in two parts, concluding to eight samples. Read More

    Ultrastructural analysis of oocytes of Rhipicephalus (Boophilus) annulatus during postengorgement period as a tool to evaluate the cytotoxic effects of amitraz and deltamethrin on the germinative cells.
    Vet Parasitol 2017 Nov 12;247:113-120. Epub 2017 Oct 12.
    Division of Parasitology, Indian Veterinary Research Institute, Izatnagar, UP 243122, India.
    The present study utilizes the ultrastructural analysis of the fully engorged female Rhipicephalus (Boophilus) annulatus ticks, as a tool to evaluate the cytotoxic potential of deltamethrin and amitraz on the germinative cells. The ultrastructural analysis of the ovary of the normal (untreated) R (B.) annulatus revealed, oocytes in different stages of development, attached to the ovary wall by pedicel cells. Read More

    Urinary concentrations of 3-(diethylcarbamoyl)benzoic acid (DCBA), a major metabolite of N,N-diethyl-m-toluamide (DEET) and semen parameters among men attending a fertility center.
    Hum Reprod 2017 Dec;32(12):2532-2539
    Department of Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Ave., Boston, MA 02115, USA.
    Study Question: Are specific gravity (SG)-adjusted urinary concentrations of 3-(diethylcarbamoyl)benzoic acid (DCBA) associated with semen parameters among men attending an academic fertility center?

    Summary Answer: Our study did not demonstrate any association between SG-adjusted urinary DCBA concentrations and semen parameters among men attending an academic fertility center.

    What Is Known Already: N,N-Diethyl-m-toluamide (DEET) is the most common active ingredient in consumer insect repellents. The recent rise in public health concerns regarding mosquito-borne diseases such as Zika, have led to an increased use of DEET insect repellents, especially among couples planning pregnancy. Read More

    Phthalate induced toxicity in prostate cancer cell lines and effects of alpha lipoic acid.
    Bratisl Lek Listy 2017 ;118(8):460-466
    Objective: The effects of dimethyl phthalate, diethyl phthalate, diisobutyl phthalate, di-n-butyl phthalate, benzylbutyl phthalate, di-2-ethylhexyl phthalate were investigated on human prostate cancer cell lines DU145 and PC3 in vitro.

    Materials And Methods: Standards of dimethyl phthalate, diethyl phthalate, di-isobutyl phthalate, dibutyl phthalate, benzyl butyl phthalate, and di-ethyl hexyl phthalate were used. Alpha lipoic acid was used as antioxidant compound. Read More

    Protecting cows in small holder farms in East Africa from tsetse flies by mimicking the odor profile of a non-host bovid.
    PLoS Negl Trop Dis 2017 Oct 17;11(10):e0005977. Epub 2017 Oct 17.
    International Centre of Insect Physiology and Ecology (icipe), Nairobi, Kenya.
    Background: For the first time, differential attraction of pathogen vectors to vertebrate animals is investigated for novel repellents which when applied to preferred host animals turn them into non-hosts thereby providing a new paradigm for innovative vector control. For effectively controlling tsetse flies (Glossina spp.), vectors of African trypanosomosis, causing nagana, repellents more powerful than plant derived, from a non-host animal the waterbuck, Kobus ellipsiprymnus defassa, have recently been identified. Read More

    Behaviors Related to Mosquito-Borne Diseases among Different Ethnic Minority Groups along the China-Laos Border Areas.
    Int J Environ Res Public Health 2017 10 15;14(10). Epub 2017 Oct 15.
    Yunnan Institute of Parasitic Diseases, Puer 665000, China.
    : In China, mosquito-borne diseases are most common in the sub-tropical area of Yunnan province. The objective of this study was to examine behaviors related to mosquito-borne diseases in different ethnic minority groups and different socioeconomic groups of people living in this region. : A stratified two-stage cluster sampling technique with probability proportional to size was used in Mengla County, Xishuangbanna Prefecture, Yunnan. Read More

    Protection of Grain Products from Sitophilus oryzae (L.) Contamination by Anti-Insect Pest Repellent Sachet Containing Allyl Mercaptan Microcapsule.
    J Food Sci 2017 Nov 14;82(11):2634-2642. Epub 2017 Oct 14.
    Dept. of Food Bioscience and Technology, College of Life Sciences and Biotechnology, Korea Univ., Seoul 02841, Republic of Korea.
    The purpose of this study was to develop an anti-insect pest repellent sachet to prevent Sitophilus oryzae (L.) (Coleoptera: Curculionidae) contamination in grain packaging. The anti-insect pest activities of essential oils (EOs) from garlic (Allium Sativum), ginger (Zingiber Officinalis), black pepper (Piper nigrum), onion (Allium cepa), and fennel (Foeniculum vulgare) as well as major compounds (allyl disulfide, AD; allyl mercaptan, AM) isolated from of garlic and onion (AD and AM) were measured against S. Read More

    Coordination of different ligands to copper(II) and cobalt(III) metal centers enhances Zika virus and dengue virus loads in both arthropod cells and human keratinocytes.
    Biochim Biophys Acta 2018 01 13;1862(1):40-50. Epub 2017 Oct 13.
    Department of Biological Sciences, Old Dominion University, Norfolk, VA, USA; Center for Molecular Medicine, Old Dominion University, Norfolk, VA, USA. Electronic address:
    Trace elements such as copper and cobalt have been associated with virus-host interactions. However, studies to show the effect of conjugation of copper(II) or cobalt(III) metal centers to thiosemicarbazone ligand(s) derived from either food additives or mosquito repellent such as 2-acetylethiazole or citral, respectively, on Zika virus (ZIKV) or dengue virus (serotype 2; DENV2) infections have not been explored. In this study, we show that four compounds comprising of thiosemicarbazone ligand derived from 2-acetylethiazole viz. Read More

    Field assessment of a novel spatial repellent for malaria control: a feasibility and acceptability study in Mondulkiri, Cambodia.
    Malar J 2017 Oct 13;16(1):412. Epub 2017 Oct 13.
    Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
    Background: Large-scale use of insecticide-treated nets and indoor residual spraying have contributed to a significant decrease in malaria transmission worldwide. Further reduction and progress towards elimination, however, require complementary control measures which can address the remaining gaps in protection from mosquito bites. Following the development of novel pyrethroids with high knockdown effects on malaria vectors, programmatic use of spatial repellents has been suggested as one potential strategy to fill the gaps. Read More

    Evaluation of the Constituents of Vetiver Oil Against Anopheles minimus (Diptera: Culicidae), a Malaria Vector in Thailand.
    J Med Entomol 2018 Jan;55(1):193-199
    Department of Entomology, Faculty of Agriculture, Kasetsart University, Bangkok, Thailand.
    The development of resistance by mosquitoes to current synthetic compounds has resulted in reduced effectiveness of prevention and control methods worldwide. An alternative nonchemical based control tools are needed to be evaluated particularly plant-derived essential oils. Several components of vetiver oil have been documented as insect repellents. Read More

    Differential Expression Profile of lncRNAs from Primary Human Hepatocytes Following DEET and Fipronil Exposure.
    Int J Mol Sci 2017 10 7;18(10). Epub 2017 Oct 7.
    Department of Entomology and Plant Pathology, North Carolina Agromedicine Institute, Campus Box 7647, 3230 Ligon Street, North Carolina State University, Raleigh, NC 27695, USA.
    While the synthesis and use of new chemical compounds is at an all-time high, the study of their potential impact on human health is quickly falling behind, and new methods are needed to assess their impact. We chose to examine the effects of two common environmental chemicals, the insect repellent ,-diethyl--toluamide (DEET) and the insecticide fluocyanobenpyrazole (fipronil), on transcript levels of long non-protein coding RNAs (lncRNAs) in primary human hepatocytes using a global RNA-Seq approach. While lncRNAs are believed to play a critical role in numerous important biological processes, many still remain uncharacterized, and their functions and modes of action remain largely unclear, especially in relation to environmental chemicals. Read More

    Adsorption and desorption of phthalic acid esters on graphene oxide and reduced graphene oxide as affected by humic acid.
    Environ Pollut 2018 Jan 5;232:505-513. Epub 2017 Oct 5.
    Department of Environmental Science, Zhejiang University, Hangzhou 310058, China; Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, Hangzhou 310058, China. Electronic address:
    The implications of humic acid (HA) regarding surface properties of graphene materials and their interactions with phthalic acid esters (PAEs) are not vivid. We report the role of HA on graphene oxide (GO) and reduced graphene oxide (RGO) for sorption-desorption behavior of PAEs. Besides higher surface area and pore volume, the hydrophobic π-conjugated carbon atoms on RGO ensured prominent adsorption capacity towards PAEs in comparison to hydrophilic GO, highlighting the hydrophobic effect. Read More

    Robust Manipulations of Pest Insect Behavior Using Repellents and Practical Application for Integrated Pest Management.
    Environ Entomol 2017 10;46(5):1041-1050
    Department of Entomology, Cornell University, 630 W. North St., Geneva, NY 14456.
    In agricultural settings, examples of effective control strategies using repellent chemicals in integrated pest management (IPM) are relatively scarce compared to those using attractants. This may be partly due to a poor understanding of how repellents affect insect behavior once they are deployed. Here we attempt to identify potential hallmarks of repellent stimuli that are robust enough for practical use in the field. Read More

    Risk assessment of a formamidine pesticide, Amitraz, focusing on thyroid hormone receptors (TRs) in rainbow trout, Oncorhynchus mykiss.
    Cell Mol Biol (Noisy-le-grand) 2017 Sep 30;63(9):29-34. Epub 2017 Sep 30.
    Faculty of Agriculture, Department of Fisheries and Aquaculture Engineering, Ankara University, Dişkapi, Ankara, Turkey.
    Amitraz, a formamidine pesticide, and their metabolites have the potential to disrupt endocrine homeostasis in a variety of organisms, nevertheless there is a lack of information concerning such effects and underlying mechanisms in any fish species.To evaluate the potential impacts of Trasil (EC; active constituent 200 g amitraz/L), a commercial product of amitraz, on thyroid hormone (TH) homeostasis of rainbow trout (Oncorhynchus mykiss); mRNA levels of thyroid hormone receptors (TRs), TRα and TRβ, were determined by RT-PCR soon after sub-lethal administration in a static bio-assay system. The sub-lethal exposure of 0. Read More

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