23,822 results match your criteria Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery[Journal]


Prevalence of geophagy and knowledge about its health effects among native Sub-Saharan Africa, Caribbean and South America healthy adults living in France.

Eat Weight Disord 2018 Dec 13. Epub 2018 Dec 13.

Service de Médecine Interne et des Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire Reims, 51092, Reims, France.

Geophagy is widespread among women from Sub-Saharan Africa, South America and the Caribbean and may persist in western countries. This practice may be associated with adverse effects such as anaemia, constipation or intestinal occlusion. We aimed to determine the prevalence of geophagy and the level of knowledge about its health effects among healthy adults originating from these countries and attending a travel medicine and international vaccination consultation in France. Read More

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December 2018

Glaucoma - Next Generation Therapeutics: Impossible to Possible.

Pharm Res 2018 Dec 13;36(2):25. Epub 2018 Dec 13.

Ophthalmology Research, Novartis Institutes for Biomedical Research, 22 Windsor Street, Cambridge, Massachusetts, 02139, USA.

The future of next generation therapeutics for glaucoma is strong. The recent approval of two novel intraocular pressure (IOP)-lowering drugs with distinct mechanisms of action is the first in over 20 years. However, these are still being administered as topical drops. Read More

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December 2018

"Just Carbon": Ideas About Graphene Risks by Graphene Researchers and Innovation Advisors.

Nanoethics 2018 22;12(3):199-210. Epub 2018 Oct 22.

2Gothenburg Research Institute, University of Gothenburg, PO Box 603, 405 30 Gothenburg, Sweden.

Graphene is a nanomaterial with many promising and innovative applications, yet early studies indicate that graphene may pose risks to humans and the environment. According to ideas of responsible research and innovation, all relevant actors should strive to reduce risks related to technological innovations. Through semi-structured interviews, we investigated the idea of graphene as a risk (or not) held by two types of key actors: graphene researchers and innovation advisors at universities, where the latter are facilitating the movement of graphene from the laboratory to the marketplace. Read More

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October 2018

Giving Voice to Patients: Developing a Discussion Method to Involve Patients in Translational Research.

Nanoethics 2018 9;12(3):181-197. Epub 2018 Jul 9.

4Wageningen University and Research, Wageningen, The Netherlands.

Biomedical research policy in recent years has often tried to make such research more 'translational', aiming to facilitate the transfer of insights from research and development (R&D) to health care for the benefit of future users. Involving patients in deliberations about and design of biomedical research may increase the quality of R&D and of resulting innovations and thus contribute to translation. However, patient involvement in biomedical research is not an easy feat. Read More

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Sustainable food systems-a health perspective.

Sustain Sci 2018 12;13(6):1505-1517. Epub 2018 Jun 12.

7Departments of Population Health and of Public Health, Environments and Society, London School of Hygiene & Tropical Medicine, London, UK.

Malnutrition in all forms, ranging from undernourishment to obesity and associated diet-related diseases, is one of the leading causes of death worldwide, while food systems often have major environmental impacts. Rapid global population growth and increases in demands for food and changes in dietary habits create challenges to provide universal access to healthy food without creating negative environmental, economic, and social impacts. This article discusses opportunities for and challenges to sustainable food systems from a human health perspective by making the case for avoiding the transition to unhealthy less sustainable diets (using India as an exemplar), reducing food waste by changing consumer behaviour (with examples from Japan), and using innovations and new technologies to reduce the environmental impact of healthy food production. Read More

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REASSURED diagnostics to inform disease control strategies, strengthen health systems and improve patient outcomes.

Nat Microbiol 2019 Jan 13;4(1):46-54. Epub 2018 Dec 13.

London School of Hygiene and Tropical Medicine, London, England.

Lack of access to quality diagnostics remains a major contributor to health burden in resource-limited settings. It has been more than 10 years since ASSURED (affordable, sensitive, specific, user-friendly, rapid, equipment-free, delivered) was coined to describe the ideal test to meet the needs of the developing world. Since its initial publication, technological innovations have led to the development of diagnostics that address the ASSURED criteria, but challenges remain. Read More

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January 2019

Catalyzing marketing innovation and competitive advantage in the healthcare industry: the value of thinking like an outsider.

BMC Health Serv Res 2018 Dec 14;18(Suppl 3):922. Epub 2018 Dec 14.

Willis-Knighton Health System, 2600 Greenwood Road, Shreveport, LA, 71103, USA.

Background: Marketing arguably is the most critical administrative responsibility associated with the pursuit and realization of growth and prosperity, making prowess in the discipline essential for any healthcare institution, especially given the competitive intensity that characterizes the industry. But in order to truly gain an advantage, healthcare establishments must tap into innovative pathways that their competitors have yet to discover. Here, thinking like an outsider can pay tremendous dividends, as health and medical organizations tend to focus inwardly, limiting their exposure to externally-derived innovations and advancements which often can supply differentiation opportunities. Read More

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December 2018

Healthcare establishments as owner-operators of digital billboards: making the most of excellent roadside visibility and high traffic counts to better connect with patients.

BMC Health Serv Res 2018 Dec 14;18(Suppl 3):928. Epub 2018 Dec 14.

Willis-Knighton Health System, 2600 Greenwood Road, Shreveport, LA, 71103, USA.

Background: Given the importance of communicating effectively with current and prospective patients, healthcare institutions must direct considerable energies toward achieving associated excellence. Pursuits usually center on addressing the marketing communications mix properly, but in order to maximize communications prowess, attention also should be directed toward incorporating emerging communications innovations, when and where possible, to bolster opportunities to connect with patients.

Discussion: In pursuit of communications excellence, Willis-Knighton Health System's executives reflected on campus dynamics in the context of modern outdoor advertising technologies, namely, digital billboards, which present electronic advertisements on-demand, around-the-clock. Read More

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December 2018

Engaging patients, enhancing patient experiences: insights, innovations, and applications.

BMC Health Serv Res 2018 Dec 14;18(Suppl 3):925. Epub 2018 Dec 14.

Department of Health Services Administration, University of Alabama at Birmingham, School of Health Professions Building, 5th Floor, 1720 2nd Avenue South, Birmingham, AL, 35294, USA.

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December 2018

Environmental and social responsibility of companies cross EU countries - Panel data analysis.

Sci Total Environ 2018 Dec 5;657:287-296. Epub 2018 Dec 5.

University of Belgrade, Technical Faculty Bor, VJ 12, 19210 Bor, Serbia; Mining and Metallurgy Institute Bor, Zeleni Bulevar 35, 19210 Bor, Serbia. Electronic address:

In recent years, the socio-environmental dimension has become a structural and strategic element of successful companies, where it is usually addressed through the concept of Corporate Social Responsibility. The challenge for business is to draft new paradigms for operational procedures and improve the business conditions towards social and environmental responsibilities. Companies focus on eco-innovations and the production of "green products". Read More

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December 2018

Outcomes After the MitraClip Procedure in Patients at Very High Risk for Conventional Mitral Valve Surgery.

Innovations (Phila) 2018 Nov/Dec;13(6):433-437

From the Divisions of Cardiothoracic Surgery and.

Objective: Approximately 50% of patients with severe symptomatic mitral regurgitation are deemed too high risk for surgery. The MitraClip procedure is a viable option for this population. Our goal was to assess outcomes and survival of patients who underwent the MitraClip procedure at an institution where mitral valve surgery is routinely performed. Read More

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Stented Versus Stentless Aortic Valve Replacement in Patients With Small Aortic Root: A Systematic Review and Meta-Analysis.

Innovations (Phila) 2018 Nov/Dec;13(6):404-416

Manchester Royal Infirmary, Manchester, United Kingdom.

Objective: The aim of the study was to compare hemodynamic and perioperative outcomes of stented against stentless aortic valve replacement in patients with small aortic root (21 mm or less).

Methods: A comprehensive search was undertaken among the four major databases (PubMed, Embase, Scopus, and Ovid) to identify all randomized and nonrandomized controlled trials comparing stentless to stented bioprosthetic valves in small aortic root patients. Odds ratios, weighted mean differences, or standardized mean differences and their 95% confidence intervals were analyzed. Read More

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Minimally Invasive and Robotic Esophagectomy: A Review.

Innovations (Phila) 2018 Nov/Dec;13(6):391-403

Division of Thoracic Surgery, Robert Tucker Hayes Foundation, University of Texas Southwestern Medical Center, Dallas, TX USA.

Great advances have been made in the surgical management of esophageal disease since the first description of esophageal resection in 1913. We are in the era of minimally invasive esophagectomy. The current three main approaches to an esophagectomy are the Ivor Lewis technique, McKeown technique, and the transhiatal approach to esophagectomy. Read More

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Heterogeneous Recommendations for Oncology Products Among Different HTA Systems: A Comparative Assessment.

Recent Results Cancer Res 2019 ;213:39-55

Public Health Department, Research Unit EA 3279, Aix-Marseille University, Marseille, France.

Rising budget constraints and demands for healthcare services create additional complexity within the decision process for resource allocation. Innovations and scientific progress have been shown to be key drivers of the increase in healthcare expenditures (1). In the context of rising medical care costs and limited resources, Health Technology Assessment (HTA) was developed as a tool to inform decision-making and to provide the rationalization behind these decisions driving resource allocation and spending for health technology products. Read More

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January 2019

"Closing the Gap": Provider Recommendations for Implementing Birth Point of Care HIV Testing.

AIDS Behav 2018 Dec 12. Epub 2018 Dec 12.

Department of Family Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, KS, 66160, USA.

Delays in traditional HIV DNA PCR testing for early infant diagnosis (EID) at 6 weeks of age result in late antiretroviral treatment (ART). Birth point of care (POC) testing is an emerging strategy with the potential to streamline EID services. We elicited providers' recommendations for introducing birth POC testing to guide strategies in Kenya and similar settings. Read More

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December 2018

Secular trends in Dietary Inflammatory Index among adults in the United States, 1999-2014.

Eur J Clin Nutr 2018 Dec 12. Epub 2018 Dec 12.

Physical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, USA.

Objective: The objective of this study was to evaluate secular trends in Dietary Inflammatory Index (DII) scores in the United States between 1999 and 2014.

Methods: Data from adults over 19 years from the 1999 to 2014 National Health and Nutrition Examination Survey (N = 39,191) were used. DII scores, at each 2-year cycle, were evaluated from a 24-h recall, including 26 food parameters for DII calculation. Read More

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December 2018

Assessment of unmet needs to address noncompliant households during polio supplemental immunization activities in Kaduna state, 2014-2016.

BMC Public Health 2018 Dec 13;18(Suppl 4):1309. Epub 2018 Dec 13.

World Health Organization Country Office, Abuja, Nigeria.

Background: Despite concerted global efforts being made to eradicate poliomyelitis, the wild poliovirus still circulates in three countries, including Nigeria. In addition, Nigeria experiences occasional outbreaks of the circulating vaccine-derived poliovirus type 2 (cVDPV2). Vaccine rejection by caregivers persists in some parts of northern Nigeria, which compromises the quality of supplemental immunization activities (SIAs). Read More

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December 2018

Targeting the last polio sanctuaries with Directly Observed Oral Polio Vaccination (DOPV) in northern Nigeria, (2014-2016).

BMC Public Health 2018 Dec 13;18(Suppl 4):1314. Epub 2018 Dec 13.

World Health Organization, Country Representative Office, Abuja, Nigeria.

Background: The declaration of poliomyelitis eradication as a programmatic emergency for global public health by the 65th World Health Assembly in 2012 necessitated innovations and strategies to achieve results. Review of the confirmed polio cases in 2013 showed that most of the cases were from non-compliant households, where parents connived with vaccinators to finger mark the children without actually vaccinating the children with oral polio vaccine or children were absent from home at the time of the visit of vaccinators.

Methods: We used pre-post design to quantify the outcomes of directly observed vaccination in 90 local government areas from 12 northern Nigeria states at very high risk of polio transmission. Read More

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December 2018

A National Survey of Transplant Surgeons and Nephrologists on Implementing Apolipoprotein L1 ( APOL1) Genetic Testing Into Clinical Practice.

Prog Transplant 2018 Dec 13:1526924818817048. Epub 2018 Dec 13.

5 Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Introduction:: There is debate over whether Apolipoprotein L1 (APOL1) gene risk variants contribute to African American (AA) live donors' (LD) increased risk of kidney failure. Little is known about factors influencing physicians' integration of APOL1 genetic testing of AA LDs into donor evaluation.

Design:: We conducted a cross-sectional survey, informed by Roger's Diffusion of Innovations theory, among nephrology and surgeon members of the American Society of Nephrology, American Society of Transplantation, and American Society of Transplant Surgeons about their practices of and attitudes about APOL1 genetic testing of AA potential LDs. Read More

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December 2018

Quasi-Experimental Evaluation of LifeCourse on Utilization and Patient and Caregiver Quality of Life and Experience.

Am J Hosp Palliat Care 2018 Dec 13:1049909118817740. Epub 2018 Dec 13.

4 Allina Health, Minneapolis, MN, USA.

Whole-person care is a new paradigm for serious illness, but few programs have been robustly studied. We sought to test the effect of LifeCourse (LC), a person-centered program for patients living with serious illness, on health-care utilization, care experience, and quality of life, employing a quasi-experimental design with a Usual Care (UC) comparison group. The study was conducted 2012 to 2017 at an upper-Midwest not-for-profit health-care system with outcomes measured every 3 months until the end of life. Read More

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December 2018

Quantitative Genetics and Genomics Converge to Accelerate Forest Tree Breeding.

Front Plant Sci 2018 22;9:1693. Epub 2018 Nov 22.

Department of Forest and Conservation Sciences, Faculty of Forestry, University of British Columbia Vancouver, BC, Canada.

Forest tree breeding has been successful at delivering genetically improved material for multiple traits based on recurrent cycles of selection, mating, and testing. However, long breeding cycles, late flowering, variable juvenile-mature correlations, emerging pests and diseases, climate, and market changes, all pose formidable challenges. Genetic dissection approaches such as quantitative trait mapping and association genetics have been fruitless to effectively drive operational marker-assisted selection (MAS) in forest trees, largely because of the complex multifactorial inheritance of most, if not all traits of interest. Read More

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November 2018

Needs and Expectations of Patients with Erectile Dysfunction: An Update on Pharmacological Innovations in Phosphodiesterase Type 5 Inhibition with Focus on Sildenafil.

Sex Med 2018 Dec 3. Epub 2018 Dec 3.

Urology and Andrology Department, CHU de Nîmes-Montpellier 1 University School of Medicine, Nîmes, France.

Introduction: Phosphodiesterase type 5 inhibitors (PDE5-Is) have an excellent efficacy and tolerability profile and remain the first-line choice for the treatment of erectile dysfunction (ED). However, ED is still an underdiagnosed and undertreated condition, and many men prematurely discontinue therapy with conventional dosage formulations despite successful intercourse.

Aim: To review the unmet needs and expectations of patients with ED and describe the latest pharmaceutical innovations in the field of PDE5-I formulations designed to address these needs, with particular reference to a new orodispersible film (ODF) formulation of the PDE5-I, sildenafil. Read More

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December 2018

[Current trends in flexible ureteroscopy: an update].

Aktuelle Urol 2018 Dec 12. Epub 2018 Dec 12.

Department of Urology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg.

Flexible ureteroscopy (fURS) has become a success story in urology. Since its implementation into the treatment of urolithiasis, fURS has demonstrated excellent clinical performance and safety. In recent years, the spread of disposable ureteroscopes has shaped the field of endoscopic stone treatment. Read More

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December 2018
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Associations between general practice characteristics with use of urgent referrals for suspected cancer and endoscopies: a cross-sectional ecological study.

Fam Pract 2018 Dec 12. Epub 2018 Dec 12.

The Health Improvement Institute (THIS), University of Cambridge, Cambridge, UK.

Background: Large variation in measures of diagnostic activity has been described previously between English general practices, but related predictors remain understudied.

Objective: To examine associations between general practice population and characteristics, with the use of urgent referrals for suspected cancer, and use of endoscopy.

Methods: Cross-sectional observational study of English general practices. Read More

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December 2018

Divergent effects of brief contemplative practices in response to an acute stressor: A randomized controlled trial of brief breath awareness, loving-kindness, gratitude or an attention control practice.

PLoS One 2018 12;13(12):e0207765. Epub 2018 Dec 12.

Center for Healthy Minds, University of Wisconsin-Madison, Madison, WI, United States of America.

Mindfulness practices are increasingly being utilized as a method for cultivating well-being. The term mindfulness is often used as an umbrella for a variety of different practices and many mindfulness-based interventions (MBIs) contain multiple styles of practice. Despite the diversity of practices within MBIs, few studies have investigated whether constituent practices produce specific effects. Read More

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December 2018

Application of the ConNECT Framework to Precision Health and Health Disparities.

Nurs Res 2018 Dec 12. Epub 2018 Dec 12.

Professor and Associate Vice Dean of Research, University of South Florida College of Nursing, Tampa, FL Founding Director, Center of Community Alliance for Research Education, Professor, Department of Population Sciences, Beckman Research Institute, City of Hope Medical Center, Duarte, CA Associate Professor, The Ohio State University, College of Nursing, Columbus, OH Department of Health Outcomes and Behavior, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612 Assistant Professor, College of Nursing, University of Utah, Salt Lake City, UT Professor, Department of Psychological Science, University of North Carolina at Charlotte, Charlotte, NC Senior Member, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL Department of Health Disparities Research, MD Anderson Cancer Center, Houston, TX Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute & Department of Oncological Sciences, University of South Florida, College of Medicine, Tampa, FL Assistant Professor, Department of Oncology Sciences, Icahn School of Medicine at Mount Sinai, New York, NY Assistant Professor, Department of Community Health Sciences, Boston University School of Public Health and Department of Social and Behavioral Sciences, and Harvard T.H. Chan School of Public Health, Boston, MA Assistant Professor, Department of Medical Social Sciences and Robert H. Lurie Comprehensive Cancer Center at Northwestern University Feinberg School of Medicine, Chicago, IL Associate Professor, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR Staff Scientist, Project Director, Biobehavioral Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA Strategic Director of Health Disparities Research, Behavioral Research Center, American Cancer Society, Atlanta, GA.

Background: An emphasis on precision health (PH) has stimulated precision medicine studies to focus on the interplay of biological, behavioral, and environmental factors with disease risks, treatments, prognoses, and outcomes affecting health disparities. It is imperative, as well, that improving health equity among underserved populations remains central to the efforts and aims of PH.

Objectives: Apply the transdisciplinary ConNECT Framework: A model for advancing behavioral medicine science and practice to foster health equity to PH by integrating a population health agenda for reducing health disparities. Read More

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December 2018
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Innovations: The Journey Continues Under New Leadership.

Authors:
Ralph J Damiano

Innovations (Phila) 2018 Dec 5. Epub 2018 Dec 5.

From the Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine at Barnes-Jewish Hospital, St. Louis, MO USA.

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December 2018

Reason and Timing for Conversion to Sternotomy in Robotic-Assisted Coronary Artery Bypass Grafting and Patient Outcomes.

Innovations (Phila) 2018 Dec 5. Epub 2018 Dec 5.

From the Divisions of Cardiac Surgery and.

Objective: Conversion to sternotomy is a primary bailout method for robotically assisted coronary artery bypass grafting procedures. The aims of this study were to identify the primary reasons for conversion from robotically assisted coronary artery bypass grafting to sternotomy and to evaluate the in-hospital outcomes in such patients.

Methods: Prospectively collected data from February 2004 to April 2017 were reviewed for 72 patients (56 men; mean age = 63. Read More

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December 2018
1 Read

A Minimally Invasive Approach for Placing Sew-On Epicardial Leads in the Child.

Innovations (Phila) 2018 Dec 5. Epub 2018 Dec 5.

LSI SOLUTIONS, Victor, NY USA.

Traditionally, pacing leads are placed transvenously, although smaller pediatric patients who require permanent pacemakers may benefit from delaying tranvenous lead placement until they are larger. Alternative, minimally invasive atrioventricular pacing options have not previously existed for this patient population, leaving many of these children with large sternotomies or thoracotomies. Using three port sites and an adjustable shaft dual-needle suturing device, we placed a steroid-eluting, sew-on epicardial lead on the right atrium of a 9-year-old patient. Read More

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December 2018
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Primary Endovascular Repair of the Ascending Aorta.

Innovations (Phila) 2018 Dec 5. Epub 2018 Dec 5.

From the Cardiac Surgery Department, Parma University Hospital, Parma, Italy.

Different case series have been published demonstrating the feasibility of endovascular repair of the ascending aorta in selected patients deemed unfit for open surgery. However, the use of commercially available stent graft in the ascending aorta remains off-label, and their excessive length often prevents their deployment in the ascending aorta. Here we report a case of successful primary endovascular repair of the ascending aorta using a physician modified off-the-shelf device. Read More

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December 2018

Conclusions of the digital health hub of the Transform Africa Summit (2018): strong government leadership and public-private-partnerships are key prerequisites for sustainable scale up of digital health in Africa.

BMC Proc 2018 15;12(Suppl 11):17. Epub 2018 Aug 15.

WHO Country Office, Kigali, Rwanda.

Background: The use of digital technologies to improve access to health is gaining momentum in Africa. This is more pertinent with the increasing penetration of mobile phone technology and internet use, and calls for innovative strategies to support implementation of the health-related Sustainable Development Goals and Universal Health Coverage on the continent. However, the huge potential benefits of digital health to advance health services delivery in Africa is yet to be fully harnessed due to critical challenges such as proliferation of pilot projects, poor coordination, inadequate preparedness of the African health workforce for digital health, lack of interoperability and inadequate sustainable financing, among others. Read More

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Positional Differences in GPS Outputs and Perceived Exertion During Soccer Training Games and Competition.

J Strength Cond Res 2018 Nov;32(11):3222-3231

Center for Sport and Exercise Science and Medicine, University of Brighton, Eastbourne, United Kingdom.

Abbott, W, Brickley, G, and Smeeton, NJ. Positional differences in GPS outputs and perceived exertion during soccer training games and competition. J Strength Cond Res 32(11): 3222-3231, 2018-Soccer training games are popular training modalities, allowing technical, tactical, and physical aspects to be trained simultaneously. Read More

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November 2018

Value-based medicine in oncology: the importance of perspective in the emerging value frameworks.

Clinics (Sao Paulo) 2018 Dec 10;73(suppl 1):e470s. Epub 2018 Dec 10.

Centro de Investigacao Translacional em Oncologia, Instituto do Cancer do Estado de Sao Paulo (ICESP), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.

Recently, professional and healthcare-related entities have launched frameworks designed to assess the value of cancer innovations in multistakeholder decision processes. Among the most visible entities that propose and implement value frameworks in oncology are the European Society of Medical Oncology (ESMO), the American Society of Clinical Oncology (ASCO), the Memorial Sloan Kettering Cancer Center (MSKCC) and the National Comprehensive Cancer Network (NCCN). However, these value frameworks have been criticized for conceptual inconsistencies, inability to include a greater variety of value criteria, and inadequate explanation of the uncertainty approach used in the modeling process. Read More

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December 2018

Trends in Attitudes to and the Use of HIV Pre-exposure Prophylaxis by Australian Gay and Bisexual Men, 2011-2017: Implications for Further Implementation from a Diffusion of Innovations Perspective.

AIDS Behav 2018 Dec 11. Epub 2018 Dec 11.

Centre for Social Research in Health, UNSW Sydney, Sydney, Australia.

Using repeated, national, online, cross-sectional surveys of Australian gay and bisexual men (GBM), we analysed trends related to HIV pre-exposure prophylaxis (PrEP). Specifically, we analysed trends in PrEP use, willingness to use PrEP, and concern about using PrEP during 2011-2017. We assessed support for GBM using PrEP and willingness to have sex with men taking PrEP between 2015 and 2017. Read More

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December 2018

Accelerated Decline in Javelin Throwing Performance in Master Athletes 70 Years and Older - Do Changes in Technique Play a Role?

Sports Med Int Open 2018 Jun 27;2(3):E79-E83. Epub 2018 Aug 27.

Manchester Metropolitan University, School of Healthcare Science, Manchester, United Kingdom.

While many older adults are immobile and frail, others still participate in competitive sports. World records of javelin throw decrease with increasing age. It is, however, unknown 1) whether the decline is linear or, as in sprint performance, accelerates beyond the age of 69; and 2) to what extent frailty-related changes in throwing technique contribute to decreasing performance. Read More

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Innovations in Personalized and Targeted Therapies for Breast Cancer.

Int J Breast Cancer 2018 14;2018:5409846. Epub 2018 Nov 14.

Lerner College of Medicine, Cleveland Clinic, 9500 Euclid Avenue/A81, Cleveland, Ohio 44195, USA.

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November 2018

Physical and physiological demands and hormonal responses in basketball small-sided games with different tactical tasks and training regimes.

J Sci Med Sport 2018 Nov 23. Epub 2018 Nov 23.

Lithuanian Sports University, Institute of Sport Science and Innovations, Lithuania.

Objectives: To evaluate external and internal training load (TL) and hormonal responses in basketball 3-versus-3 small-sided games (SSGs).

Design: Randomized repeated-measures study.

Methods: Twelve male basketball players participated to four 3-versus-3 SSGs characterized by different tactical tasks (offensive; defensive) and training regimes (long-intermittent: three 4-min bouts with 2' rest in between; short-intermittent: six 2-min bouts with 1' rest in between). Read More

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November 2018

Current challenges in health information technology-related patient safety.

Health Informatics J 2018 Dec 11:1460458218814893. Epub 2018 Dec 11.

Center for Innovations in Quality, Effectiveness and Safety, Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA.

We identify and describe nine key, short-term, challenges to help healthcare organizations, health information technology developers, researchers, policymakers, and funders focus their efforts on health information technology-related patient safety. Categorized according to the stage of the health information technology lifecycle where they appear, these challenges relate to (1) developing models, methods, and tools to enable risk assessment; (2) developing standard user interface design features and functions; (3) ensuring the safety of software in an interfaced, network-enabled clinical environment; (4) implementing a method for unambiguous patient identification (1-4 Design and Development stage); (5) developing and implementing decision support which improves safety; (6) identifying practices to safely manage information technology system transitions (5 and 6 Implementation and Use stage); (7) developing real-time methods to enable automated surveillance and monitoring of system performance and safety; (8) establishing the cultural and legal framework/safe harbor to allow sharing information about hazards and adverse events; and (9) developing models and methods for consumers/patients to improve health information technology safety (7-9 Monitoring, Evaluation, and Optimization stage). These challenges represent key "to-do's" that must be completed before we can expect to have safe, reliable, and efficient health information technology-based systems required to care for patients. Read More

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December 2018

Untangling the role of diverse social dimensions in the diffusion of microfinance.

Appl Netw Sci 2016 22;1(1):14. Epub 2016 Nov 22.

Department of Mathematics and Computer Science, Av. Paisos Catalans, 26, Tarragona, 43007 Spain.

Ties between individuals on a social network can represent different dimensions of interactions, and the spreading of information and innovations on these networks could potentially be driven by some dimensions more than by others. In this paper we investigate this issue by studying the diffusion of microfinance within rural India villages and accounting for the whole multilayer structure of the underlying social networks. We define a new measure of node centrality, diffusion versatility, and show that this is a better predictor of microfinance participation rate than previously introduced measures defined on aggregated single-layer social networks. Read More

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November 2016

Differences in perceptions of e-cigarettes across daily and non-daily users.

Addict Behav 2018 Dec 5;90:415-420. Epub 2018 Dec 5.

Department of Psychology, University of Houston, Houston, TX, United States; Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; Health Institute, University of Houston, Houston, TX, United States. Electronic address:

Objective: E-cigarette use has increased significantly over the past decade. Among the growing population of e-cigarette users, several pattern-based subgroups have emerged, including daily and non-daily users. Daily users are at greater risk for experiencing negative health consequences from use. Read More

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December 2018
1 Read

Adjuvant Therapy for Biliary Tract Cancers: Desperately Seeking Data.

J Oncol Pract 2018 Dec;14(12):719-720

Center for Innovations in Quality, Effectiveness, and Safety at the Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX.

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December 2018

Remodeling Medicaid.

Authors:
Joey Berlin

Tex Med 2018 Jul 1;114(7):16-21. Epub 2018 Jul 1.

House calls, yoga classes, and community networks are among the value-based innovations making Medicaid more patient-centered and more penny-wise. Read More

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Factor Analysis of Negative Symptom Items in the Structured Interview for Prodromal Syndromes.

Schizophr Bull 2018 Dec 8. Epub 2018 Dec 8.

Department of Psychology, Department of Psychiatry, Department of Medical Social Sciences, Institute for Policy Research, Institute for Innovations in Developmental Sciences, Northwestern University, Evanston, IL.

Background: Negative symptoms occur early in the clinical high risk (CHR) state and indicate increased risk of conversion to psychotic disorder and poor functional outcome. However, while the negative symptom domain has shown to be parsimoniously explained by a 2-factor construct in schizophrenia, there has yet to be an established factor structure of negative symptoms in CHR.

Methods: 214 individuals meeting the Structured Interview for Psychosis-Risk Syndromes (SIPS) criteria for CHR were recruited through 3 active research programs in the United States. Read More

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December 2018

Multimodal Intravascular Photoacoustic and Ultrasound Imaging.

Biomed Eng Lett 2018 May 26;8(2):193-201. Epub 2018 Mar 26.

Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, CA 92617 USA.

The rupture of atherosclerotic plaques is the leading cause of death in developed countries. Early identification of vulnerable plaque is the essential step in preventing acute coronary events. Intravascular photoacoustic (IVPA) technology is able to visualize chemical composition of atherosclerotic plaque with high specificity and sensitivity. Read More

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Temporal Changes on the Risks and Complications of Posttransplantion Diabetes Mellitus Following Cardiac Transplantation.

J Transplant 2018 8;2018:9205083. Epub 2018 Nov 8.

Montreal Heart Institute, Université de Montréal, Montreal, QC, Canada.

Background: Recent changes in the demographic of cardiac donors and recipients have modulated the rate and risk, associated with posttransplant diabetes mellitus (PTDM). We investigated the secular trends of the risk of PTDM at 1 year and 3 years after transplantation over 30 years and explored its effect on major outcomes.

Methods: Three hundred and three nondiabetic patients were followed for a minimum of 36 months, after a first cardiac transplantation performed between 1983 and 2011. Read More

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November 2018

Cross-sectional study to determine viral hepatitis knowledge in different urban populations in Brazil.

World J Hepatol 2018 Nov;10(11):867-876

Laboratory of Viral Hepatitis, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040360, Brazil.

Aim: To evaluate viral hepatitis knowledge among individuals from different resource areas and health conditions to identify possible gaps.

Methods: A cross-sectional, descriptive study was carried out among 447 individuals from five distinct populations in Brazil: Southeast Viral Hepatitis Ambulatory ( = 100), South ( = 89) and Northeast ( = 114) Health Center, Southeast ( = 77) and Northeast ( = 67) low resource areas. All individuals answered a questionnaire assessing sociodemographic characteristics and viral hepatitis awareness. Read More

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November 2018
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Nonvascularized Bone Graft Reconstruction of the Irradiated Murine Mandible: An Analogue of Clinical Head and Neck Cancer Treatment.

J Craniofac Surg 2018 Dec 10. Epub 2018 Dec 10.

Section of Plastic and Reconstructive Surgery, Michigan Medicine, Ann Arbor, MI.

Nonvascularized bone grafts (NBGs) represent a practical method of mandibular reconstruction that is precluded in head and neck cancer patients by the destructive effects of radiotherapy. Advances in tissue-engineering may restore NBGs as a viable surgical technique, but expeditious translation demands a small-animal model that approximates clinical practice. This study establishes a murine model of irradiated mandibular reconstruction using a segmental iliac crest NBG for the investigation of imperative bone healing strategies. Read More

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December 2018

Opportunities to observe and measure intangible inputs to innovation: Definitions, operationalization, and examples.

Proc Natl Acad Sci U S A 2018 Dec;115(50):12638-12645

Social and Decision Analytics Laboratory, Biocomplexity Institute of Virginia Tech, Arlington, VA 22203.

Measuring the value of intangibles is not easy, because they are critical but usually invisible components of the innovation process. Today, access to nonsurvey data sources, such as administrative data and repositories captured on web pages, opens opportunities to create intangibles based on new sources of information and capture intangible innovations in new ways. Intangibles include ownership of innovative property and human resources that make a company unique but are currently unmeasured. Read More

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December 2018

How science and technology developments impact employment and education.

Authors:
Wendy Martinez

Proc Natl Acad Sci U S A 2018 Dec;115(50):12624-12629

Office of Survey Methods Research, US Bureau of Labor Statistics, Washington, DC 20212

A better understanding of how developments in science and technology influence the creation of new occupations and subsequent changes in educational programs can help decision makers at all levels of our society. As a result of research and development efforts, innovations are achieved, resulting in the creation of new occupations and the demand for employees with expertise in these new areas. To fulfill the demand, universities and colleges often revise their programs to address these needs. Read More

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December 2018