Hear Res 2019 04 22;375:14-24. Epub 2019 Feb 22.
Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, UT, 84132, USA; Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, UT, 84132, USA; Department of Otolaryngology Head and Neck Surgery, University of Utah, Salt Lake City, UT, 84132, USA. Electronic address:
Usher syndrome (USH) is the leading cause of inherited combined vision and hearing loss. However, mutations in most USH causative genes lead to other diseases, such as hearing loss only or vision loss only. The molecular mechanisms underlying the variable disease manifestations associated with USH gene mutations are unclear. Read More