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Otol Neurotol 2019 Apr;40(4):e393-e398

Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.

Objective: To demonstrate characteristic nystagmus findings in acute otitis media (AOM) complicated by serous labyrinthitis and discuss the mechanism of direction-changing positional nystagmus (DCPN) in this condition.

Patients: A patient with AOM complicated by serous labyrinthitis on the left side.

Intervention: Video nystagmography and 3D fluid attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI). Read More

Cochlear Implants Int 2019 Jan 20;20(1):47-50. Epub 2018 Sep 20.

a Department of Otorhinolaryngology , SMS Medical College and Hospitals , Jaipur , India.

Introduction: Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in the synthesis of the beta chains of hemoglobin. Iron overload occurs in thalassemia, with blood transfusion therapy being the major cause. Deferoxamine continues to be the mainstay of therapy to remove excess iron in patients requiring long-term transfusions. Read More

Diagn Interv Imaging 2018 Nov 13;99(11):679-687. Epub 2018 Sep 13.

Department of Neuroradiology, Lariboisière University Hospital, 75010 Paris, France. Electronic address:

Purpose: To report the postoperative magnetic resonance imaging (MRI) features after superior semicircular canal plugging in patients with Minor syndrome.

Materials And Methods: The MRI examinations with 3D T2-weighted SPACE sequence of 12 patients with superior semicircular canal dehiscence syndrome (SCDS) were retrospectively assessed. Two radiologists independently evaluated the presence of a filling defect of the superior semicircular canal above the superior ampulla and the common crus using an oblique plane parallel to the superior semicircular canal (Pöschl's plane). Read More

Int J Pediatr Otorhinolaryngol 2018 Oct 24;113:102-109. Epub 2018 Jul 24.

Department of Otorhinolaryngology, Hannover Medical University, Carl-Neuberg-Straße 1, 30625, Hannover, Germany; German Hearing Center, Hannover Medical University, Karl-Wiechert-Allee 3, 30625, Hannover, Germany.

Objectives: Bacterial meningitis can cause a labyrinthitis. Consequences often are intracochlear soft tissue neoformation (cochlear obliteration) or intracochlear osteoneogenesis (cochlear ossification) and deafness. Cochlear implantation becomes challenging and hearing rehabilitation is complicated. Read More

Semin Hear 2018 Aug 20;39(3):229-242. Epub 2018 Jul 20.

Center for Evaluation of Balance Disorders in Children (EFEE), Robert Debré University Hospital, Paris, France.

The purpose of this study was to report the prevalence of vestibular impairment (VI) in children (  = 2,528) referred for complete vestibular testing because of balance disorders (BD) or hearing loss (H). A VI was shown in 51.5% of the children tested (1,304/2,528). Read More

Otolaryngol Head Neck Surg 2018 Nov 3;159(5):908-913. Epub 2018 Jul 3.

2 Department of Radiology, Emory University, Atlanta, Georgia, USA.

Objectives: To describe patient characteristics, audiometric outcomes, and magnetic resonance imaging (MRI) signal patterns in patients with suspected labyrinthine hemorrhage.

Study Design: Retrospective review.

Setting: Tertiary medical center. Read More

Acta Vet Scand 2018 May 22;60(1):31. Epub 2018 May 22.

Department of Diagnostic Medicine/Pathobiology, Kansas State Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Kansas State University, K-221 Mosier Hall, Manhattan, KS, 66506-5802, USA.

Background: An aural cholesteatoma, more appropriately named tympanokeratoma, is an epidermoid cyst of the middle ear described in several species, including dogs, humans and Mongolian gerbils. The cyst lining consists of stratified, keratinizing squamous epithelium with central accumulation of a keratin debris. This case report describes vestibular ganglioneuritis and perineuritis in a dog with chronic otitis, bilateral tympanokeratomas and presumed extension of otic infection to the central nervous system. Read More

Comp Med 2018 Apr 12. Epub 2018 Apr 12.

Labyrinthitis is inflammation of the membranous and bony labyrinth of the inner ear. Typical portals of entry includehematogenous spread from the cochlear vasculature, passage of otitis media pathogens through the round window, and mostcommonly, meningogenic spread from the subarachnoid space. The sequela of chronic inner ear inflammation is labyrinthitisossificans, in which inner ear structures are replaced by fibrous and osseous tissues. Read More

GMS Curr Top Otorhinolaryngol Head Neck Surg 2017 18;16:Doc02. Epub 2017 Dec 18.

HNO-Gemeinschaftspraxis, Main-Taunus-Zentrum, Sulzbach, Germany.

Vertigo is a multisensory syndrome that otolaryngologists are confronted with every day. With regard to the complex functions of the sense of orientation, vertigo is considered today as a disorder of the sense of direction, a disturbed spatial perception of the body. Beside the frequent classical syndromes for which vertigo is the leading symptom (e. Read More

PLoS One 2017 4;12(10):e0186038. Epub 2017 Oct 4.

Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.

Although recent advances in magnetic resonance imaging (MRI) techniques have contributed to the detection of tiny lesions in the internal auditory canal (IAC) that may be responsible for sudden sensorineural hearing loss (SSNHL), there have been relatively few studies on the clinical characteristics of intra-labyrinthine hemorrhage (ILH) and labyrinthitis versus those regarding IAC tumors. Our purpose was to investigate the frequency of those IAC lesions on MRI and their clinical characteristics. Initial MRIs of 200 patients with SSNHL (93 men, 107 women; mean age = 48. Read More

Auris Nasus Larynx 2018 Apr 22;45(2):248-253. Epub 2017 Sep 22.

Department of Otorhinolaryngology and Head and Neck Surgery, Beaumont Hospital and Blackrock Clinic, Dublin, Ireland.

Objective: To explore the aetiology of and to evaluate the importance of MRI investigation on the posterior semicircular canal benign paroxysmal positional vertigo in an Irish population.

Methods: A retrospective observational study of 500 patients with posterior semicircular canal benign paroxysmal positional vertigo, diagnosed and treated by the senior author over a 10-year period. Most patients underwent an MRI brain and inner ear, following the same scan protocol. Read More

Audiol Neurootol 2017 24;22(2):116-123. Epub 2017 Aug 24.

Otopathology Laboratory, Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.

The Cogan syndrome is a rare disorder characterized by nonsyphilitic interstitial keratitis and audiovestibular symptoms. Profound sensorineural hearing loss has been reported in approximately half of the patients with the Cogan syndrome resulting in candidacy for cochlear implantation in some patients. The current study is the first histopathologic report on the temporal bones of a patient with the Cogan syndrome who during life underwent bilateral cochlear implantation. Read More

Acta Otolaryngol 2017 Dec 21;137(12):1226-1232. Epub 2017 Aug 21.

c Department of Otolaryngology-Head and Neck Surgery , Hanyang University Guri Hospital , Guri , Korea.

Objectives: To evaluate the magnetic resonance imaging (MRI) findings of labyrinthine hemorrhage as a cause of sudden sensorineural hearing loss (SSNHL).

Methods: MRI scans of 59 patients with SSNHL were retrospectively analyzed and compared to clinical features and audiometry data. MR images included pre-enhanced T1-weighted, 3D FLAIR volume isometric turbo spin-echo acquisition (VISTA), post-enhanced T1-weighted and 4-h-delayed enhanced FLAIR VISTA, and 3D thin-section proton density-weighted images. Read More

Otol Neurotol 2017 06;38(5):e21-e25

*Department of Otorhinolaryngology †Department of Radiology ‡Department of Clinical Genomics §Department of Audiology, Mayo Clinic, Rochester, Minnesota.

Objective: To describe a novel case of congenital profound bilateral sensorineural hearing loss in a patient with bilateral nodular internal auditory canal and labyrinthine enhancement and temporal bone dysplasia.

Patients: A 76-day-old female was referred to the authors' center for evaluation of congenital deafness. Behavioral observations and objective audiometric evaluation demonstrated bilateral profound sensorineural hearing loss and a comprehensive multidisciplinary evaluation identified compound heterozygous pathogenic variants in MYO7A, a gene associated with Usher Syndrome Type 1B or DFNB2. Read More

Vestn Otorinolaringol 2016;81(6):13-16

City Children's Clinical Hospital of St. Vladimir, Moscow, Russia, 107140.

The objective of the present study was to evaluate the potential of CT and MRI for diagnostics of congenital and acquired pathology of the inner ear in the deaf patients. Two groups of the patients were examined. The first group consisted of 75 patients with congenital or acquired deafness etiology. Read More

Clin Radiol 2017 Mar 26;72(3):267.e1-267.e12. Epub 2016 Dec 26.

University Department of Otolaryngology, Head and Neck Surgery, Eberhard-Karls-University Tübingen, Germany.

Aim: To compare image quality and evaluate its clinical importance in common temporal bone pathologies of a pTX-SPACE (parallel transmit [pTX] three-dimensional turbo spin-echo with variable flip angle [SPACE]) magnetic resonance imaging (MRI) sequence improved for spatial resolution to a standard-SPACE sequence exhibiting the same scan time at 3 T.

Materials And Methods: Thirty-four patients were examined using a standard-SPACE and resolution improved pTX-SPACE sequence at 3 T MRI. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and image quality were assessed. Read More

Ann Otol Rhinol Laryngol 2017 Feb 24;126(2):89-95. Epub 2016 Nov 24.

1 Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota, USA.

Objective: To quantitatively assess the effect of serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans on vestibular hair cells, dark cells, and transitional cells.

Methods: We examined human temporal bone specimens with serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans, then compared them with age-matched control groups without labyrinthitis. We evaluated the density of type I and II vestibular hair cells, dark cells, and transitional cells in the peripheral sensorial organs. Read More

Ann Otol Rhinol Laryngol 2017 Feb 19;126(2):163-165. Epub 2016 Nov 19.

1 Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Utah, Salt Lake City, Utah, USA.

Objectives: To share results and recommendations for management of penetrating cochlear injury.

Methods: A patient underwent repair of a penetrating cochlear injury after a projectile led to a traumatic cochleostomy with a narrow miss of the facial nerve and intracranial carotid artery.

Results: Postoperatively, the patient's audiogram demonstrated a pure tone average of 47. Read More

Handb Clin Neurol 2016 ;137:279-93

Department of Oto-Rhino-Laryngology, Centre Hospitalier Universitaire de Saint Etienne, Saint Etienne, France.

This chapter will focus on vertigo/dizziness due to inner-ear malformations, labyrinthine fistula, otosclerosis, infectious processes, and autoimmune inner-ear disorders. Inner-ear malformation due to dehiscence of the superior semicircular canal is the most recently described inner-ear malformation. Vertigo/dizziness is typically induced by sound and pressure stimuli and can be associated with auditory symptoms (conductive or mixed hearing loss). Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2016 Jul;30(14):1127-1130

Department of Otolaryngology,People's Hospital Peking University,Beijing,100044,China.

Reclassified the total deafness and flat type of sudden deafness,identified the relationship between new classification and hearing prognosis.To analyze 192 cases of patients with sudden deafness,especially for 159 cases of flat type and total deafness patients for further curve type classification,classified as rise,decline and consistent,analysis the possible factors with hearing in multiple factors using regression analysis.According to age group of 45 years old,>0. Read More

Acta Otolaryngol 2016 Nov 31;136(11):1193-1195. Epub 2016 May 31.

a Department of Otorhinolaryngology , Showa University , Tokyo , Japan.

Objectives: The authors would like to confirm a fluid pathway from the scala tympani to the organ of Corti, and to observe its morphological changes.

Methods: A staining solution for succinic dehydrogenase was perfused with phenazine methosulfate in the scala tympani of living guinea pigs (n = 5) under deep anesthesia. After fixation, the cochleas were eventually embedded in epon. Read More

Acta Otorrinolaringol Esp 2017 Jan - Feb;68(1):29-37. Epub 2016 May 27.

Sección de Neurorradiología y Radiología de cabeza-cuello, Área Clínica de Imagen Médica, Hospital Universitario y Politécnico La Fe, Valencia, España.

Most cases of acute otitis media resolve with antibiotics and imaging is not required. When treatment fails or a complication is suspected, imaging plays a crucial role. Since the introduction of antibiotic treatment, the complication rate has decreased dramatically. Read More

Otolaryngol Head Neck Surg 2016 10 24;155(4):635-40. Epub 2016 May 24.

Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota, USA

Objective: To quantitatively demonstrate and classify the histopathologic changes in the cochlea of the human temporal bones with labyrinthitis ossificans (LO).

Study Design: Comparative human temporal bone study.

Setting: Tertiary academic medical center. Read More

Acta Otolaryngol 2016 Oct 16;136(10):1011-6. Epub 2016 May 16.

a Department of Otolaryngology-Head and Neck Surgery , Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences , Okayama , Japan.

Conclusion: Significant expression of macrophage migration inhibitory factor and its receptor (CD74) was observed in both the middle ear and inner ear in experimental otitis media in mice. Modulation of macrophage migration inhibitory factor and its signaling pathway might be useful in the management of inner ear inflammation due to otitis media.

Objectives: Inner ear dysfunction secondary to otitis media has been reported. Read More

Adv Otorhinolaryngol 2016 26;77:23-6. Epub 2016 Apr 26.

Pneumolabyrinth is a rare condition with air bubbles existing in the vestibule and/or cochlea. We report a case of pneumolabyrinth without trauma that was suspected to be caused by labyrinthitis. A 65-year-old man presented with vertigo and hearing loss in the left ear after catching a cold. Read More

Aust Fam Physician 2016 Apr;45(4):190-4

Background: Dizziness is a common and very distressing presentation in general practice. In more than half of these cases, the dizziness is due to vertigo, which is the illusion of movement of the body or its surroundings. It can have central or peripheral causes, and determining the cause can be difficult. Read More

JAMA Otolaryngol Head Neck Surg 2016 Apr;142(4):364-9

Department of Otolaryngology, University of Minnesota, Minneapolis.

Importance: Better understanding of the effects of suppurative labyrinthitis (SL) on cochlear elements will aid the development of new approaches to treat its sequelae and complications in the ear.

Objective: To quantitatively evaluate the effects of SL on cochlear elements in humans.

Design, Setting, And Participants: A comparative study was conducted at a tertiary academic medical center from October 20, 2014, to January 3, 2015, of the histopathologic characteristics of 28 archived human temporal bone samples from 19 deceased patients with SL and 20 temporal bone samples from 14 deceased, age-matched controls. Read More

Am J Otolaryngol 2016 Mar-Apr;37(2):83-8. Epub 2015 Oct 8.

Department of Otolaryngology, University of Minnesota, Minneapolis, MN, USA. Electronic address:

Purpose: To determine histopathological findings in the cochlea of human temporal bones with serous labyrinthitis.

Materials And Methods: We compared human temporal bones with serous labyrinthitis (20 cases) associated with silent otitis media and without serous labyrinthitis (20 cases) to study location of serous labyrinthitis, the degree of endolymphatic hydrops, number of spiral ganglion cells and hair cells, loss of fibrocytes in the spiral ligament, and areas of the spiral ligament and stria vascularis.

Results: The serous labyrinthitis caused significant loss of outer hair cells in the lower basal (P=0. Read More

Acta Otolaryngol 2016 Jun 21;136(6):559-63. Epub 2016 Jan 21.

a Department of Otorhinolaryngology-Head and Neck Surgery , Konkuk University Medical Center, Konkuk University School of Medicine , Seoul , Republic of Korea.

Conclusion The patients with serous labyrinthitis caused by acute otitis media (AOM) exhibited various patterns of nystagmus in which direction-fixed irritative-type nystagmus was the most common pattern. Differential effects on inner ear function by toxic or inflammatory mediators may be responsible for the various manifestation of nystagmus. Objective This study aimed to investigate nystagmus patterns in patients with serous labyrinthitis, and discuss possible mechanisms. Read More

Hear Res 2016 Mar 13;333:118-126. Epub 2016 Jan 13.

Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea; Sensory Organ Research Institute, Seoul National University Medical Research Center, Seoul, Republic of Korea. Electronic address:

Purpose: To compare the inner ear enhancement after intratympanic injection of two widely used gadolinium (Gd) agents by 9.4 T micro-magnetic resonance imaging (MRI) and to investigate the effects of Gd on the inner ear.

Methods: Twelve ears of six rats received intratympanic administration of 1/5 diluted Gd agents: gadoterate meglumine (Gd-DTPA) for the left ear and gadodiamide (Gd-DTPA-BMA) for the right ear. Read More

Braz J Otorhinolaryngol 2016 Jan-Feb;82(1):82-7. Epub 2015 Dec 11.

Department of Otorhinolaryngology, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-UNIFESP), São Paulo, SP, Brazil; Department of Head and Neck Surgery, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-UNIFESP), São Paulo, SP, Brazil.

Introduction: Suppurative labyrinthitis continues to result in significant hearing impairment, despite scientific efforts to improve not only its diagnosis but also its treatment. The definitive diagnosis depends on imaging of the inner ear, but it is usually clinically presumed.

Objective: To analyze the clinical factors and hearing outcomes in patients with labyrinthitis secondary to middle ear infections and to discuss findings based on imaging test results. Read More

Neuroscience 2016 Mar 21;316:261-78. Epub 2015 Dec 21.

INSERM - UMR 1051, Institute for Neurosciences of Montpellier, Montpellier, France; University Montpellier 1 & 2, Montpellier, France; ENT Department, University Hospital Gui de Chauliac, Montpellier, France. Electronic address:

Cochlear fibrosis is a common finding following cochlear implantation. Evidence suggests that cochlear fibrosis could be triggered by inflammation and epithelial-to-mesenchymal cell transition (EMT). In this study, we investigate the mechanisms of cochlear fibrosis and the risk/benefit ratio of local administration of the anti-inflammatory drug dexamethasone (DEX) and antimitotic drug aracytine (Ara-C). Read More

Otol Neurotol 2016 Feb;37(2):132-6

*Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota, U.S.A. †Gebze Fatih State Hospital, Otolaryngology Division, Gebze, Kocaeli, Turkey ‡Giresun A. Ilhan Ozdemir State Hospital, Otolaryngology Division, Giresun, Turkey §Paparella Ear Head and Neck Institute, Minneapolis, Minnesota, U.S.A.

Hypothesis: To compare histopathologic findings in the cochlea of human temporal bones with versus without intralabyrinthine hemorrhage.

Background: Hemorrhagic labyrinthitis can cause sensorineural damage, sudden hearing loss, and vertigo. Yet, to our knowledge, no studies have quantitatively described histopathologic effects of intralabyrinthine hemorrhage on the elements of the cochlea. Read More

J Laryngol Otol 2015 Dec;129(12):1238-42

St Thomas' Hearing Implant Centre,St Thomas' Hospital,Guy's and St Thomas' NHS Foundation Trust,London,UK.

Background: Auditory implantation into the inner ear is increasingly performed for a variety of indications. Infective complications are rare, but when they occur they can have devastating consequences.

Case Reports: This paper reports two cases where vestibular sequestration of the bony labyrinth developed following implantation into the middle ear. Read More

Laryngoscope 2016 07 4;126(7):1656-61. Epub 2015 Nov 4.

Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, U.S.A.

Objectives/hypothesis: To evaluate the effectiveness of cochlear measures obtained by high-resolution computed tomography (HRCT) scan in predicting depth of cochlear implant insertion.

Study Design: Retrospective case review.

Methods: Patients who underwent cochlear implantation in an academic referral center between 2010 and 2013 were considered. Read More

Acta Otolaryngol 2015 6;135(12):1253-8. Epub 2015 Aug 6.

a 1 Department of Otorhinolaryngology, Clínica Universidad de Navarra , Pamplona, Spain.

Conclusion: The low clinical efficacy of the treatment for patients included in this work correlates with no noticeable effect on the vestibular function.

Objective: To assess follow-up in patients with idiopathic and secondary Ménière's disease after treatment with intra-tympanic dexamethasone and correlate clinical findings with changes in the vestibular-ocular reflex elicited after stimulation of each of the six semicircular canals.

Methods: This is a single center retrospective review of patients presenting the clinical symptomatology of Meniérè's disease treated with intra-tympanic dexamethasone. Read More

Laryngorhinootologie 2015 Aug 4;94(8):530-54. Epub 2015 Aug 4.

Menière`s disease is one of the most common inner ear and vestibular disorders. It is defined as the idiopathic syndrome of endolymphatic hydrops (ELH). Despite the development of several different animal models of ELH, its etiology and pathogenesis is still unresolved. Read More

Otol Neurotol 2015 Sep;36(8):1417-20

*Division of Otology-Neurotology, Department of Otolaryngology-Head and Neck Surgery; †Department of Pathology; and ‡Kresge Hearing Research Institute, Department of Otolaryngology-Head and Neck Surgery, University of Michigan Health System, Ann Arbor, Michigan, U.S.A.

Objectives: To describe the rationale, intraoperative details, and histopathologic findings discovered when treating an unusual case of apogeotropic horizontal canal positional vertigo with a transmastoid labyrinthectomy.

Patient: A single case report.

Intervention: Therapeutic. Read More

Audiol Neurootol 2015 19;20 Suppl 1:21-30. Epub 2015 May 19.

Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Centre Freiburg, Freiburg, Germany.

For adult patients with single-sided deafness (SSD), treatment with a cochlear implant (CI) is well established as an acceptable and beneficial hearing rehabilitation method administered routinely in clinical practice. In contrast, for children with SSD, CI has been applied less often to date, with the rationale to decide either on a case-by-case basis or under the realm of clinical research. The aim of our clinical study was to evaluate the longitudinal benefits of CI for a group of children diagnosed with SSD and to compare their outcomes with respect to patient characteristics. Read More

J Immunol 2015 Apr 16;194(8):3953-61. Epub 2015 Mar 16.

Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095;

Cochlear inflammatory diseases, such as tympanogenic labyrinthitis, are associated with acquired sensorineural hearing loss. Although otitis media is extremely frequent in children, tympanogenic labyrinthitis is not commonly observed, which suggests the existence of a potent anti-inflammatory mechanism modulating cochlear inflammation. In this study, we aimed to determine the molecular mechanism involved in cochlear protection from inflammation-mediated tissue damage, focusing on IL-10 and hemoxygenase-1 (HMOX1) signaling. Read More

Ann Otol Rhinol Laryngol 2015 Aug 10;124(8):649-54. Epub 2015 Mar 10.

Department of Otolaryngology, Head & Neck Surgery and Audiology, Rigshospitalet, University of Copenhagen, Denmark.

Introduction: It has been suggested that remodeling of the otic capsule is highly suppressed by the action of anti-resorptive signals emanating from structures of the inner ear space. Labyrinthitis ossificans (LO) is a severe complication to bacterial meningitis and is characterized by destruction of inner ear structures by the formation of new bone. The aim of this study was to explore the impact of LO on bone remodeling of the otic capsule. Read More

Ear Nose Throat J 2015 Mar;94(3):108-10

Department of Diagnostic Radiology, Changi General Hospital, 2 Simei St. 3, Singapore 529889.

We report the case of a 42-year-old man who presented with fluctuating bilateral sensorineural hearing loss that subsequently progressed to a complete hearing loss, and we describe the correlation between the clinical and radiologic features of this case. To the best of our knowledge, this is the first report to demonstrate imaging evidence of progression from autoimmune inner ear disease to labyrinthitis ossificans. This is also the first reported case of a reversal of a loss of labyrinthine CISS (constructive interference in a steady state) signal, suggesting that T2-weighted hyposignal may be attributable to an alteration in labyrinthine fluid content and not to fibrosis only. Read More

Laryngorhinootologie 2015 Jan;94(1):6-7

J Laryngol Otol 2015 Feb 26;129(2):183-6. Epub 2015 Jan 26.

ENT Department,CUF Descobertas Hospital,Lisbon,Portugal.

Background: Lyme disease is an uncommon tick-borne multisystemic infection caused by Borrelia burgdorferi. The most common clinical manifestation is erythema migrans. In this report, a very unusual presentation of this condition is described, in which sudden onset sensorineural hearing loss was the sole presenting symptom. Read More

Acta Otorrinolaringol Esp 2015 Jul-Aug;66(4):224-33. Epub 2014 Oct 12.

Sección de Neurorradiología y Radiología Cabeza-Cuello, Servicio de Radiología Hospital Universitario y Politécnico La Fe, Valencia, España.

Introduction: Congenital malformations and acquired lesions of the inner ear are characterised by small structural changes in this region. In recent decades, treatment options have improved considerably. At the same time, there has been a great advancement in diagnostic methods, obtaining high-resolution labyrinth images. Read More

Radiographics 2014 Sep-Oct;34(5):E133-49

From the Department of Radiology (J.Y.Y., M.E.R.) and Department of Otolaryngology- Head and Neck Surgery (N.M.Y.), Northwestern University Feinberg School of Medicine, Chicago, Ill; Department of Medical Imaging (J.Y.Y., M.E.R.) and Division of Pediatric Otolaryngology (N.M.Y.), Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E Chicago Ave, Chicago, IL 60611; and Knowles Hearing Center, School of Communication, Northwestern University, Evanston, Ill (N.M.Y.).

Cochlear implantation is the only U.S. Food and Drug Administration-approved treatment for children with marked bilateral sensorineural hearing loss. Read More

Cochlear Implants Int 2014 Nov 5;15(6):337-40. Epub 2014 Sep 5.

Objective: To report a case of cochlear ossification as a result of neurosarcoidosis in a patient with bilateral profound sensorineural hearing loss.

Study Design: Case report: Setting University teaching hospital, tertiary referral center.

Patient: Forty-year-old man with neurosarcoidosis and bilateral profound sensorineural hearing loss. Read More

J Laryngol Otol 2014 Jul;128(7):618-20

Department of Otolaryngology-Head and Neck Surgery,Mackay Memorial Hospital Taipei Branch,New Taipei City,Taiwan.

Objective: To estimate the incidence of tympanogenic labyrinthitis ossificans.

Methods: The records of patients treated with mastoidectomy for various tympanogenic aetiologies from January 2007 to December 2011 were retrospectively reviewed. Patients whose high-resolution computed tomography scans showed evidence of labyrinthine calcification of the temporal bone were enrolled. Read More

Otol Neurotol 2014 Oct;35(9):1533-5

Department of Otolaryngology-Head and Neck Surgery, University of Texas at Southwestern, Dallas, Texas, U.S.A.

Objectives: To determine the prevalence of MRI abnormalities in adults undergoing cochlear implantation and to correlate abnormalities to audiology data.

Study Design: Case series.

Setting: Academic medical center. Read More

Otol Neurotol 2014 Jun;35(5):905-10

*New York University School of Medicine; †Department of Radiology, and ‡Department of Otolaryngology, Columbia University College of Physicians and Surgeons, New York, New York, U.S.A.

Objective: Magnetic resonance imaging is the gold standard in retrocochlear imaging; however, its role in management of inner ear diseases remains poorly defined. In this study, we investigate the utility of MRI in defining the nature of intracochlear pathology.

Study Design: A retrospective review of 11 patients with inner ear abnormalities on MRI between 2010 and 2013. Read More