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J Hand Surg Eur Vol 2020 Jun 3:1753193420927999. Epub 2020 Jun 3.

Department of Orthopaedic Surgery, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain.

One hundred and sixty patients were enrolled in a prospective randomized controlled trial to assess whether a steroid injection through the dorsal web space was less painful than the palmar midline technique in the treatment of trigger digits and whether they were equally effective. There were 116 women and 44 men with a mean age of 60 years. The mean visual analogue score for pain during the injection was 3. Read More

J Hand Surg Am 2020 May 22. Epub 2020 May 22.

Division of Hand and Upper Extremity Surgery, Department of Orthopedics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA. Electronic address:

Purpose: Corticosteroid injections are commonly used to treat thumb carpometacarpal arthritis in adults. We aimed to define the timing of surgery following an initial corticosteroid injection and identify patient-specific factors that influence the likelihood of repeat injection or surgery.

Methods: We performed a retrospective analysis of all patients who underwent a first-time corticosteroid injection for carpometacarpal arthritis between 2009 and 2017. Read More

Open Access Rheumatol 2020 28;12:47-54. Epub 2020 Apr 28.

Department of Special Surgery, Division of Orthopedics, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.

Background: Spontaneous rupture of extensor pollicis longus (EPL) tendon is a rare condition often found in patients actively having regular extensive use of hands and fingers especially the thumb. In this article, we report 7 cases of spontaneous rupture of EPL tendon and investigate the associated factors and treatment outcome.

Methods: Retrospectively, the databases for the 7 cases were retrieved and studied. Read More

Dermatol Surg 2020 Apr 28. Epub 2020 Apr 28.

All authors are affiliated with the Department of Dermatology, La Paz University Hospital, Madrid, Spain.

Background: Raynaud's phenomenon (RP) is a clinical syndrome characterized by recurrent episodes of digital vasospasm triggered by exposure to physical and chemical agents or emotional stress. Although many pharmacologic treatments have been tested, there is still no cure or gold standard therapy. Botulinum toxin treatment has been proved to reduce pain and increase arterial blood flow in treated hands of adult patients with RP. Read More

Bone Joint J 2020 May;102-B(5):600-605

Nuffield Orthopaedic Centre, Oxford, UK.

Aims: Base of thumb osteoarthritis (BTOA) is a common age-related disease which has a significant negative impact upon quality of life. Our aim was to assess current UK practice in secondary care with regard to the nature of non-surgical treatments, the surgical procedures most commonly performed, and factors influencing the surgical decision-making process.

Methods: Ten consecutive patients undergoing surgery for BTOA between March 2017 and May 2019 were prospectively identified in 15 UK centres. Read More

Rev Esp Cir Ortop Traumatol 2020 Mar 18. Epub 2020 Mar 18.

Departamento de Cirugía Ortopédica y Traumatología, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, España; Departamento de Ciencias Médicas y Quirúrgicas, Facultad de Medicina, Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, España.

Background And Objective: Corticosteroid injection is an effective treatment for trigger digits but the pain during the injection is an ever-present side effect. Since the palmar skin has a high density of sensitive receptors, injecting through dorsal skin could be less painful. Our aim was to assess whether a dorsal technique through the dorsal web is safe for extra-sheath injection of trigger fingers and thumb. Read More

Orv Hetil 2020 Mar;161(11):419-424

Egészségtudományi Kar, Alapozó Egészségtudományi Intézet, Morfológiai és Fiziológiai Tanszék, Semmelweis Egyetem Budapest, Vas u. 17., 1088.

De Quervain's tendinopathy affects the region of the wrist and the hand. Thumb motion becomes painful. This illness is caused by a degenerative process rather than inflammation. Read More

Toxins (Basel) 2020 Feb 18;12(2). Epub 2020 Feb 18.

GlaxoSmithKline K.K., Tokyo 107-0052, Japan.

In many countries, 400 units (U) is the maximum dose of onabotulinumtoxinA available to treat upper limb spasticity, but few studies have demonstrated the optimal use of this dose. In the double-blind phase of this randomized, controlled trial, we compared the efficacy and safety of 400 vs. 240 U onabotulinumtoxinA in patients with post-stroke upper limb spasticity. Read More

Surgeon 2020 Feb 8. Epub 2020 Feb 8.

Department of Plastic Surgery, Royal Preston Hospital, Sharoe Green Lane, Preston PR2 9HT, UK. Electronic address:

Aims: Accidental injury to digits with Adrenaline Auto-injectors (AAIs) is becoming increasingly common. Digital AAI injury causes painful ischaemia that can lead to necrosis and patient anxiety. There is a lack of understanding amongst surgeons regarding how to manage these injuries. Read More

J Wrist Surg 2020 Feb 9;9(1):19-21. Epub 2019 Jul 9.

Division of Hand & Upper Extremity Surgery, The Rothman Institute, Philadelphia, Pennsylvania.

 The volume of the carpometacarpal joint of the thumb (TCMC) and its capacity to accommodate fluid injection is unknown.  The purpose of the present study is to assess the volume of the TCMC.  Forty-two thumbs undergoing surgical treatment for symptomatic TCMCJ osteoarthritis (OA) were evaluated. Read More

J Hand Surg Am 2020 Feb 16;45(2):123-130.e1. Epub 2019 Dec 16.

Department of Surgery and Perioperative Care, Dell Medical School, The University of Texas at Austin, Austin, TX. Electronic address:

Purpose: Operative treatment of trapeziometacarpal osteoarthritis (TMC OA) is discretionary. There is substantial surgeon-to-surgeon variation in offers of surgery. This study assessed factors associated with variation in recommendation of operative treatment to patients with TMC OA. Read More

Rev Prat 2019 May;69(5):507-509

Service de rhumatologie, hôpital Lariboisière, Paris, France.

"Osteoarthritis (OA) is one of the most common disorders of joints. The joints most frequently affected are the hip, knee and the hand, notably the base of the thumb. Use of imaging to diagnose OA, whatever its localization should be limited to plain X-Rays in the majority of cases. Read More

Rheumatol Int 2019 Dec 14;39(12):2167-2175. Epub 2019 Oct 14.

Department of Physical Therapy, Faculty of Health Sciences, University of Malaga, Arquitecto Francisco Peñalosa St, 29010, Malaga, Spain.

Thumb carpometacarpal osteoarthritis (TCMC-OA) is a progressively disabling, debilitating condition presenting with thumb base pain and hand functional impairment. Platelet-rich plasma has been used widely for the management of musculoskeletal pathologies, OA being among them. To our knowledge, only a few cases have been previously reported on this topic until now. Read More

Arthritis Care Res (Hoboken) 2019 Oct 10. Epub 2019 Oct 10.

Research Center of the CHUM, Montreal, Quebec, Canada.

Objective: This systematic review (SR) aimed to synthesize the literature on the efficacy of existing non-surgical interventions for trapeziometacarpal osteoarthritis (TMO).

Methods: A medical librarian conducted an electronic search in 16 databases. Two authors independently carried out study selection, data extraction, and risk of bias assessment. Read More

Acta Anaesthesiol Scand 2020 02 28;64(2):173-179. Epub 2019 Oct 28.

Division of Anaesthesiology, Department of Anaesthesiology, Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals, Geneva, Switzerland.

Background: TOF-Cuff is a modified blood pressure cuff used to monitor neuromuscular block. We compared the assessment of spontaneous neuromuscular recovery between TOF-Cuff (test device) and TOF Watch SX (reference device).

Methods: Forty patients aged 18-65 years undergoing elective surgery were enrolled. Read More

Plast Reconstr Surg Glob Open 2019 Aug 8;7(8):e2360. Epub 2019 Aug 8.

Creighton University School of Medicine, Omaha, Nebr.

Trigger finger (TF) is a common referral to a hand surgeon, with people with diabetess being the most at-risk population. Abnormal thickening, scarring, and inflammation occur at the A1 pulley and flexor tendon, and histological changes correlate well with the clinical severity of TF. Corticosteroid injections decrease the thickness of the A1 pulley and are considered a first-line treatment. Read More

BMJ Open 2019 09 11;9(9):e027507. Epub 2019 Sep 11.

NDORMS, University of Oxford, Oxford, UK

Objective: To evaluate the effectiveness of injection-based therapy in base of thumb osteoarthritis.

Design: Systematic review and meta-analysis.

Data Sources: MEDLINE and EMBASE via OVID, CINAHL and SPORTDiscus via EBSCO were searched from inception to 22 May 2018. Read More

Rev Bras Ortop (Sao Paulo) 2019 May 27;54(3):253-260. Epub 2019 Jun 27.

Faculdade de Ciências Médicas e da Saúde, Pontifícia Universidade Católica de São Paulo, Sorocaba, SP, Brasil.

 The purpose of this anatomical study was to analyze the possibility of transferring radial nerve branches to the supinator muscle to reinnervate the posterior interosseous nerve (PIN) originating from the C7-T1 roots.  Thirty members of 15 cadavers, all male, prepared with an intra-arterial glycerol and formaldehyde solution injection, were dissected.  All dissected limbs presented at least one branch intended for the superficial and the deep heads of the supinator muscle. Read More

Clin Orthop Relat Res 2019 Aug;477(8):1879-1888

A.D. Sobel, A.E.M. Eltorei, B. Weiss, A-P C. Weiss, Department of Orthopaedic Surgery, Brown University, Providence, RI, USA P.K. Mansuripur, Permanente Medical Group, Napa-Solano, Vallejo, CA, USA.

Background: Numerous patient-related risk factors have been identified as contributors to patient progression to operative treatment of stenosing tenosynovitis (STS). Identifying patients most at risk of undergoing surgery after receiving a corticosteroid injection would enable health care providers to identify patients most likely to benefit from nonsurgical treatment.

Questions/purposes: (1) What proportion of prospectively enrolled patients with a new diagnosis of STS did not require further intervention after a first, second, or third injection when offered up to three corticosteroid injections? (2) Which identifiable risk factors present at the initial evaluation in patients with STS are associated with the patient opting for surgical release after a trial of one, two, or three corticosteroid injections?

Methods: One hundred ninety-six patients with a presumed diagnosis of STS were evaluated between March 2014 and June 2015, and 160 patients with 186 affected fingers were prospectively enrolled after a new diagnosis of STS was made during the study period. Read More

J Stomatol Oral Maxillofac Surg 2019 Sep 18;120(4):297-300. Epub 2019 Jul 18.

Service de chirurgie plastique, CHU de Dijon, 14, rue Paul-Gaffarel, 21000 Dijon, France. Electronic address:

Introduction: Pedicled flaps and free-tissue transfer flaps are used routinely to reconstruct hard and soft tissue defects in head and neck, limb, hand, thoracic and abdominopelvic reconstructive surgery. But failure remains a constant concern, particularly in free-tissue transfers. Usually failure is due to blood supply compromise. Read More

Mol Genet Genomic Med 2019 09 18;7(9):e843. Epub 2019 Jul 18.

Key Laboratory of Reproductive Health, Liaoning Province Research Institute of Family Planning, China Medical University, Huanggu District, Shenyang, China.

Background: Crouzon syndrome is a rare and complex autosomal dominant craniosynostosis syndrome with a prevalence of approximately 1 in 60,000 births. The typical features are craniosynostosis, proptosis, midfacial hypoplasia, and noncranial manifestations, including deformities in the cervical spine, elbow, and fingers. Crouzon syndrome is usually caused by pathogenic variants in the fibroblast growth factor receptor 2 (FGFR2) gene. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Jun;33(6):721-725

Department of Hand and Microsurgery, Xiangya Hospital Central South University, Changsha Hunan, 410008, P.R.China.

Objective: To explore the feasibility and effectiveness of radial collateral artery polyfoliate perforator flap in repair of resurfacing soft tissue defect of hand.

Methods: Between September 2017 and September 2018, the radial collateral artery polyfoliate perforator flaps were transplanted to repair 5 cases of two adjacent wounds of hand and wide or irregular wounds. All patients were male, aged from 27 to 52 years, with an average of 42. Read More

Clin Plast Surg 2019 Jul;46(3):407-413

Division of Plastic and Reconstructive Surgery, Harvard Medical School, Massachusetts General Hospital, Wang Building, 55 Fruit Street, Boston, MA 02114, USA. Electronic address:

Thumb carpometacarpal arthritis is a common condition treated by hand surgeons. This condition most frequently affects the elderly and postmenopausal women. Nonoperative treatment options include activity modification, orthoses, and injections. Read More

Medicine (Baltimore) 2019 May;98(19):e15506

Department of Physical Medicine and Rehabilitation.

Intra-articular hyaluronic acid (HA) is widely used to treat symptomatic osteoarthritis (OA) in the carpometacarpal joint (CMCJ) of the thumb. However, although apparently effective and relatively safe, intra-articular HA injections act relatively slowly. Therefore, a nonsteroidal anti-inflammatory drug could be added for more prompt pain relief. Read More

N Z Vet J 2019 Sep 3;67(5):241-248. Epub 2019 Jun 3.

c Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine , Urmia University , Urmia , Iran.

Aims: To develop a technique for the injection of local anaesthetic into the spinal canal of broiler chickens by first determining the ideal location for needle placement based on anatomy and histology, and then using the developed technique to assess the onset and duration of action of three doses of lidocaine.

Methods: Two-month-old Ross broiler chickens (n = 30) were used in this study. Computed tomography imaging followed by anatomical examination of fresh cadavers (n = 6) were used to identify a suitable intervertebral space for injection of local anaesthetic, and landmarks to locate this space. Read More

Hand (N Y) 2019 May 1:1558944719846572. Epub 2019 May 1.

1 The University of Chicago Medicine & Biological Sciences, IL, USA.

Background: Arthritis involving the thumb carpometacarpal (CMC) joint is common in the adult population. Initial treatment includes corticosteroid injections. Injections can be performed with image guidance to assist with placement; however, the clinical benefits are unclear. Read More

Eur J Pain 2019 Aug 9;23(7):1351-1357. Epub 2019 May 9.

Department of Rehabilitation, Kochi Medical School, Kochi University, Nankoku, Japan.

Background: Splinting is a quite common intervention for the first carpometacarpal (CMC) osteoarthritis, however, underlying mechanisms of biomechanical and analgesic effects has not been fully investigated. The aim of this study was to develop an experimental basal thumb pain model and to elucidate the effects of CMC splinting on the pain profile and motor function.

Methods: In 14 healthy subjects, experimental basal thumb pain was induced by hypertonic saline injection into the dorsal radial ligament located on base of the first metacarpal bone. Read More

Tidsskr Nor Laegeforen 2019 Apr 5;139(7). Epub 2019 Apr 5.

J Hand Surg Am 2019 Apr;44(4):296-303

Department of Orthopaedics, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI.

Purpose: Most studies have demonstrated little difference in the outcome of the various techniques proposed for the surgical treatment of thumb carpometacarpal (CMC) arthritis. However, the difficulty and time required to perform each technique vary widely. In addition, the introduction of recent implants has increased the cost of the overall procedure. Read More

J Immunother 2019 05;42(4):136-141

Department of Hematology-Oncology, Norris Cotton Cancer Center, Lebanon, NH.

Talimogene laherparepvec (T-VEC) is approved for unresected stage III-IV malignant melanoma. T-VEC has a direct cytotoxic effect and enhances the antitumor immunity of host cells. Immune checkpoints inhibitors also enhance the immunity of host cells by increasing the recruitment of antigen-presenting cells or activation and restoration of T-cell functions. Read More

Drug Deliv Transl Res 2019 08;9(4):795-801

State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, 368 Youyi Road, Wuhan, 430062, China.

Background: The tuberculin skin test (TST) is a long-established screening method for tuberculosis. However, the Mantoux technique is often difficult to reliably perform, which affects testing results and safety, which causes local skin pain and pruritus.

Methods: In this study, dissolving microneedle-array patches (MNP) were used to deliver purified protein derivative (PPD) tuberculin into the skin. Read More

Mol Clin Oncol 2019 Mar 21;10(3):339-342. Epub 2019 Jan 21.

Department of Orthopaedics and Traumatology, Saiful Anwar Hospital, Brawijaya University, Malang, Jawa Timur 65112, Indonesia.

Unicameral bone cyst (UBC) or simple bone cyst (SBC) is a benign cystic lesion commonly found in the humerus and femur that is mainly encountered during childhood. The currently available treatments for UBC of the hand commonly involve curettage, bone grafting, partial resection with or without grafting, multiple drilling, fracture immobilization and observation alone, and steroid injection. We herein report a case treated with total resection of the cyst and non-vascularized fibular graft in a 9-year-old right-handed female patient. Read More

BMJ Open 2019 01 9;9(1):e022553. Epub 2019 Jan 9.

Methodologist, centre de Recherche Clinique, CHD Vendée, La Roche-sur-Yon, Pays de la Loire, France.

Introduction: Osteoarthritis of the trapeziometacarpal joint affects approximately 10%-25% of women, especially those who are postmenopausal. It may result in thumb dysfunction. Among the treatments, intra-articular injections of corticosteroid (CS) and hyaluronic acid (HA) are both effective and recommended. Read More

A A Pract 2019 Jun;12(11):426-429

Departement of Orthopedic Surgery, Orthopedic Surgery, Rodez General Hospital, Rodez, France.

The outcome of upper limb tendon transfer surgery is improved when the patient is able to voluntarily contract specific muscles during the surgical procedure. Tumescent local anesthesia is suitable, but we describe an alternative option that involves the novel management of an axillary block. A 47-year-old man, injured in a motor vehicle crash, exhibited a thumb extensor deficit because of severe muscular trauma to the forearm. Read More

Adv Ther 2019 01 27;36(1):187-199. Epub 2018 Nov 27.

University of Nevada at Reno, Reno, NV, USA.

Introduction: The objective of the study was to investigate the efficacy and safety of repeated incobotulinumtoxinA injections for the treatment of upper-limb post-stroke spasticity in adults.

Methods: Adults 18-80 years of age with post-stroke upper-limb spasticity who completed the 12-week randomized, double-blind, placebo-controlled main period (MP) of a phase 3 trial (NCT01392300) were eligible to enrol in the 36-week open-label extension period (OLEX). The OLEX included three treatment cycles at fixed 12-week injection intervals; subjects were injected with 400 U incobotulinumtoxinA into the affected upper limb. Read More

World Neurosurg 2019 Feb 19;122:e1374-e1380. Epub 2018 Nov 19.

Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA. Electronic address:

Background: First carpometacarpal (CMC) joint osteoarthritis (OA) is commonly encountered in clinical practice. The preferred surgical option when conservative therapy fails varies with the stage and nature of the disease. Denervation of the first CMC joint is a relatively new procedure for managing stable thumb CMC joint OA. Read More

J Hand Surg Am 2019 Aug 9;44(8):694.e1-694.e5. Epub 2018 Nov 9.

Department of Plastic Surgery, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

Purpose: The aim of this study was to analyze the durability of the treatment results of the thumb and first web contractures in Dupuytren disease with collagenase Clostridium histolyticum.

Methods: Twelve patients (14 hands) were followed for an average of 35 months (range, 24-42 months). Two patients (3 hands) were excluded, yielding 11 hands available for assessment. Read More

Medicine (Baltimore) 2018 Nov;97(45):e13123

College of Korean Medicine, Dongguk University, Gyeongju, Republic of Korea.

Rationale: Sprains, stretching or tearing of ligaments are common injuries. Clinicians should try to prevent acupuncture-associated vasovagal responses (AAVR) when treating patients with such injuries. In this study, we report the treatment of frequent sprains of various body parts in a patient with a history of AAVR using only TA (a 7-herb extract consisting of Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophora tonkinensis, Aucklandia lappa, Aquilaria agallocha, and Carthamus tinctorius L. Read More

RMD Open 2018 11;4(2):e000734. Epub 2018 Oct 11.

Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.

To update the evidence on efficacy and safety of non-pharmacological, pharmacological and surgical interventions for hand osteoarthritis (OA), a systematic literature review was performed up to June 2017, including (randomised) controlled trials or Cochrane systematic reviews. Main efficacy outcomes were pain, function and hand strength. Risk of bias was assessed. Read More

Cartilage 2018 Oct 20:1947603518805230. Epub 2018 Oct 20.

1 2nd Orthopaedic Department, School of Medicine, National and Kapodistrian University of Athens, Konstantopoulio Hospital of Nea Ionia "Agia Olga", Athens, Greece.

Various systematic reviews have recently shown that intra-articular platelet-rich plasma (IA-PRP) can lead to symptomatic relief of knee osteoarthritis for up to 12 months. There exist limited data on its use in small joints, such as the trapeziometacarpal joint (TMJ) or carpometacarpal joint (CMCJ) of the thumb. A prospective, randomized, blind, controlled, clinical trial of 33 patients with clinical and radiographic osteoarthritis of the TMJ (grades: I-III according to the Eaton and Littler classification) was conducted. Read More

J Hand Surg Eur Vol 2018 Dec 18;43(10):1106-1110. Epub 2018 Oct 18.

3 Department of Surgery, University of Michigan, Ann Arbor, MI, USA.

Truven MarketScan® Databases were used to identify patients with thumb carpometacarpal arthritis who underwent surgical treatment. Pre-operative corticosteroid or hyaluronic acid injections were identified, as were post-operative complications. Multivariable regressions assessed the relationship between injections and complications. Read More

Rev Bras Ortop 2018 Sep-Oct;53(5):575-581. Epub 2018 Aug 2.

Universidade Federal de São Paulo (Unifesp), Escola Paulista de Medicina, São Paulo, SP, Brazil.

Objective: The goal of this study was to describe anatomical variations and clinical implications of anterior interosseous nerve. In complete anterior interosseous nerve palsy, the patient is unable to flex the distal phalanx of the thumb and index finger; in incomplete anterior interosseous nerve palsy, there is less axonal damage, and either the thumb or the index finger are affected.

Methods: This study was based on the dissection of 50 limbs of 25 cadavers, 22 were male and three, female. Read More

BMJ Case Rep 2018 Aug 29;2018. Epub 2018 Aug 29.

Plastic Surgery, Addenbrooke's Hospital, Cambridge, UK.

Local corticosteroid injections are frequently used in the management of trigger finger. We present a case of a 56-year-old woman who developed an acute horseshoe abscess of the hand after injection of corticosteroid and local anaesthetic into the left thumb. This was managed successfully with intravenous antibiotics, operative intervention and early mobilisation. Read More

J Pharmacopuncture 2017 Sep 30;20(3):227-229. Epub 2017 Sep 30.

Health Science Unit (PEC), Hong Kong Physically Handicapped & Able Bodied Association, Kowloon, Hong Kong.

Fibrosis of skeletal muscle following acupuncture is an iatrogenic disorder. The present case illustrates a patient with a unilateral fibrotic formation on a thumb muscle after acupuncture injection therapy with red sage. The patient in the present case was a counter-terrorism police officer with right-handedness; he noted a palpable nodule three months after injection therapy at his left first dorsal interosseous in which the acupuncture point LI4 (He Gu) is located. Read More

Hand (N Y) 2020 Mar 30;15(2):215-219. Epub 2018 Jul 30.

Rutgers New Jersey Medical School, Newark, USA.

De Quervain tenosynovitis is commonly seen in patients who perform repetitive wrist ulnar deviation with thumb abduction and extension. Previous studies comparing nonsurgical options have contributed to a lack of consensus about ideal management. This study's purpose was to analyze results in prospectively randomized patients treated with either corticosteroid injection (CSI) alone versus CSI with immobilization. Read More

J Hand Surg Eur Vol 2019 Feb 10;44(2):161-166. Epub 2018 Jul 10.

1 Department of Orthopedic Surgery, Mayo Clinic Rochester, Rochester, MN, USA.

Ehlers-Danlos Syndrome is a connective tissue disorder that results in joint and generalized tissue hyperlaxity, predisposing patients to early onset arthritis. An institutional database spanning 1999-2016 was reviewed for all patients with symptomatic carpometacarpal arthritis and coexisting Ehlers-Danlos Syndrome, resulting in 14 thumbs amongst nine patients followed clinically for a median of 5.9 years (range 1-15). Read More

Clin Med Insights Arthritis Musculoskelet Disord 2018 21;11:1179544118782901. Epub 2018 Jun 21.

Service de Rhumatologie, Hôpital Nord Franche-Comté, Belfort, France.

Purpose: To assess safety and search predictive factors of efficacy of a single intra-articular injection of a mannitol-modified hyaluronic acid (HA) viscosupplement, in patients having trapeziometacarpal (TMC) osteoarthritis (OA).

Methods: Patients with symptomatic TMC OA, not adequately relieved by analgesic therapy and/or by the use of a thumb splint, were included in a 3-month prospective multicentre open-label trial. All underwent plain radiographs with the Kapandji incidences allowing the Dell radiological grade assessment (1-4). Read More

J Am Acad Orthop Surg 2018 Aug;26(16):562-571

From University Orthopedics and the Department of Orthopaedics, Warren Alpert Medical School of Brown University (Dr. Weiss), and the Department of Orthopaedics, Warren Alpert Medical School of Brown University, Providence, RI (Dr. Goodman).

The thumb basal joint is the second most common site of osteoarthritis in the hand, and osteoarthritis of this joint can contribute to painful movement and debilitating function. To achieve a high degree of prehensile and manipulative function, this highly mobile joint is constrained by both the saddle morphology of the trapezium and a stout complement of ligamentous constraints. The disease proceeds progressively with several wear patterns. Read More