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Aesthet Surg J 2019 Jan 14. Epub 2019 Jan 14.

Department of Maxillofacial Plastic Surgery, Division of Dental and Maxillofacial Surgery and the Department of Public Health and Community Medicine, Unit of Epidemiology and Medical Statistics, G.B. Rossi Hospital and Medical University of Verona, Verona, Italy.

Background: The bad outcomes of a facial trauma could have a strongly negative psychological impact and compromise patient's quality of life. Unfortunately, surgery cannot always solve this problem or give an acceptable result.

Objectives: Aesthetic medicine treatments with injectables may provide a solution that is minimally invasive and more accepted by the patients in improving bad outcomes after facial trauma. Read More

Ned Tijdschr Geneeskd 2019 Jan 3;163. Epub 2019 Jan 3.

Erasmus MC, afd. Dermatologie, Rotterdam.

The use of fillers for cosmetic improvement is increasing. As a result, the number of complications is rising too. Being confronted with facial nodules of unknown origin, many doctors who are not involved in cosmetic medicine are not inclined to consider filler complication as part of a differential diagnosis. Read More

Plast Reconstr Surg 2019 Jan;143(1):53-63

Albany and New York, N.Y.; Sacramento, Calif.; Munich, Germany; Zurich, Switzerland; and Salzburg, Austria From the Department of Medical Education, Albany Medical College; private practice; Facial Plastic and Reconstructive Surgery, University of California, Davis Medical Center; the Department for Hand, Plastic and Aesthetic Surgery, Ludwig Maximilian University; the Division of Thoracic Surgery, University Hospital Zurich; and the Department of Radiology, Paracelsus Medical University Salzburg & Nuremberg.

Background: Injection of soft-tissue fillers into the facial fat compartments is frequently performed to ameliorate the signs of facial aging. This study was designed to investigate the functional anatomy of the deep facial fat compartments and to provide information on the effects of injected material in relation to age and gender differences.

Methods: Forty fresh frozen cephalic specimens of 17 male and 23 female Caucasian body donors (mean age, 76. Read More

Vestn Oftalmol 2018 ;134(5):61-71

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

Purpose: To evaluate the effectiveness of injectable implants made of hyaluronic acid gel (HAG) in ophthalmoplastics.

Material And Methods: The study included 57 patients (37 patients with lagophthalmos related to acute or chronic facial nerve palsy, endocrine ophthalmopathy; 20 patients with enophthalmos, anophthalmic syndrome). Depending on filler particle size, the patients received either intrapalpebral or intraorbital HAG injection. Read More

J Cosmet Dermatol 2018 Dec 25;17(6):1025-1030. Epub 2018 Oct 25.

Aesthetic Medicine Centre, Amsterdam, The Netherlands.

Calcium hydroxylapatite (CaHA) is a commonly used soft tissue filler for aesthetic facial improvement, in particular for the lower and mid-face. The golden standard for upper facial filler indications is hyaluronic acid (HA) injection. In this report we investigate the safety, efficacy and complication rates after injections of CaHA to the upper third of the face using a variety of different techniques. Read More

Dermatol Surg 2018 11;44 Suppl 1:S32-S41

Department of Plastic Surgery, Lenox Hill Hospital, New York, New York.

Background: Calcium hydroxylapatite (CaHA) is approved to correct moderate-to-severe wrinkles and folds and soft-tissue volume loss in the face and hands. More recently, subdermal injection using diluted CaHA has been used to improve skin laxity.

Objective: To review evidence for the safe and effective use of diluted CaHA in the face and body and provide best practice recommendations. Read More

Dermatol Surg 2018 11;44 Suppl 1:S10-S18

Galderma Aesthetics, Uppsala, Sweden.

Background: Acne scarring affects most patients with acne and have a negative impact on quality of life. New effective treatment options offering minimal downtime are therefore needed.

Objective: To evaluate improvement in overall facial appearance after hyaluronic acid (HA) treatment of atrophic acne scars. Read More

Dermatol Surg 2018 11;44 Suppl 1:S2-S4

Department of Dermatology, Carruthers Dermatology Centre, Vancouver, British Columbia, Canada.

Background: Worldwide, the brow is the most common facial site to receive aesthetic treatment. However, the forehead above the brows has been comparatively less well studied with respect to both neuromodulators and fillers. Age-related remodeling of the forehead with loss of facial bone has been demonstrated on detailed radiographic studies. Read More

Clin Cosmet Investig Dermatol 2018 10;11:467-475. Epub 2018 Oct 10.

Victoria Park Medispa, Montreal, QC, Canada,

Background: Loss of the viscoelastic properties of the skin is a primary sign of aging and contributes to the appearance of wrinkles. Hyaluronic acid (HA) fillers are one of the most commonly used treatments for age-related soft-tissue reduction and volume loss. Evidence is also emerging that HA fillers rejuvenate the skin. Read More

Aesthet Surg J 2018 Oct 18. Epub 2018 Oct 18.

Division of Plastic Surgery, Hospital Le Belvedere, Mont Saint Aignan, France.

Background: Although many facelift techniques incorporate fat grafting with tissue repositioning and removal, the intermediate and long-term changes in facial volume after these techniques is unknown. Whereas fillers for facial volume have predictable life spans, we know little about the facial volume changes following fat grafting with facelift surgery.

Objectives: To track the short-term and long-term effects on midfacial volume change. Read More

J Plast Reconstr Aesthet Surg 2019 Jan 27;72(1):131-136. Epub 2018 Sep 27.

Department of Plastic and Reconstructive Surgery, University Hospital Nice, Pasteur 2, 30, avenue de la Voie Romaine, 06000 Nice, France.

Background: Over the past decade, cosmetic injections of dermal fillers or fat have become a popular procedure in facial rejuvenation in an overconsuming society. However, complications such as arterial embolism and occlusion can occur even with experienced injectors, especially in high-risks zones namely the glabella, the nasal dorsum or the nasolabial fold. The aim of this study was to define the vascular danger zones of the infraorbital area in order to provide guidelines helping avoid them. Read More

Int J Biol Macromol 2018 Dec 1;120(Pt B):1682-1695. Epub 2018 Oct 1.

Department of Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM) Selangor, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, Malaysia. Electronic address:

Hyaluronic acid (HA) plays multifaceted role in regulating the various biological processes such as skin repairmen, diagnosis of cancer, wound healing, tissue regeneration, anti-inflammatory, and immunomodulation. Owing to its remarkable biomedical and tissue regeneration potential, HA has been numerously employed as one of the imperative components of the cosmetic and nutricosmetic products. The present review aims to summarize and critically appraise recent developments and clinical investigations on cosmetic and nutricosmetic efficacy of HA for skin rejuvenation. Read More

Dermatol Ther 2018 11 25;31(6):e12722. Epub 2018 Sep 25.

Clinica Médica Dr. Davi de Lacerda, São Paulo, São Paulo, Brazil.

Injectable fillers have become one of the most performed aesthetical treatments worldwide over the past two decades. They are frequently applied to the face, offering effective and safe alternatives to more invasive surgical procedures. Nevertheless, there are serious risks associated with filler-based treatment. Read More

Acta Dermatovenerol Alp Pannonica Adriat 2018 Sep;27(3):165-167

Department of Dermatology and Venereology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Among several skin fillers developed in recent decades, hyaluronic acid (HA) fillers have become the material of choice. They are safe, long-lasting, not immunogenic, and cost effective, and they can be removed with hyaluronidase. Unfortunately, early and delayed complications can also occur following HA filler injection. Read More

J Drugs Dermatol 2018 Sep;17(9):1015

When rejuvenating the face with soft tissue fillers, one must consider its structural framework, and patient specific goals/needs holistically to achieve natural results. Read More

Ophthalmic Plast Reconstr Surg 2018 Nov/Dec;34(6):e189-e192

Gavin Herbert Eye Institute, University of California, Irvine, Irvine, California, U.S.A.

A 51-year-old woman presented with no light perception vision of the right eye 12 hours after another provider injected calcium hydroxylapatite into the glabella and dorsum of the nose. Exam and fluorescein angiography demonstrated optic nerve edema and choroidal hypoperfusion consistent with ischemia of the posterior ciliary circulation. The central retinal circulation appeared intact. Read More

J Craniofac Surg 2018 Oct;29(7):e726-e727

Department of Auricular Reconstruction, Plastic Surgery Hospital, Peking Union Medical College, Beijing, China.

Skin necrosis is a rare but severe potential complication after injection of hyaluronic acid (HA). Based on the understanding of the causes and mechanisms of this complication, many precautions have been proposed. Still, this adverse reaction happened from time to time. Read More

J Cutan Aesthet Surg 2018 Apr-Jun;11(2):51-59

Renewderm Skin Hair Laser Aesthetics Centre, Mumbai, Maharashtra, India.

Volumetric rejuvenation with fillers is a minimally invasive technique used for facial volume restoration. Volume restoration demands adequate knowledge of fat pads and vascularity of the face and the understanding of the depletion patterns. Volumetric restoration with injectable has witnessed a paradigm shift in the last decade with a global rejuvenation, acquiring a predominant emphasis over focal wrinkle filling to restore the depletion pattern of facial fat layers. Read More

Plast Surg (Oakv) 2018 Aug 19;26(3):154-159. Epub 2018 Apr 19.

Liverpool John Moores University, Merseyside, Liverpool, United Kingdom.

This study reports on an empirically underdocumented practice in contemporary aesthetic enhancement culture, the self-injection of unregulated DIY Botox and dermal filler kits purchased online. Data were collected from 4 online discussion forums containing disclosures in relation to use of DIY kits and analyzed using ethnographic content analysis. Motivation to source DIY Botox and dermal fillers online was grounded in desire to avoid financial cost of professional services and a lack of confidence in practitioners. Read More

J Am Acad Dermatol 2018 09;79(3):423-435

Division of Dermatology, Loyola University Medical Center, Maywood, Illinois.

Injectable fillers and neuromodulators are used for a range of indications pertaining to the correction of facial aging and disfigurement. Fillers can correct soft tissue loss, depressed scars, and atrophy or asymmetry induced by systemic or local disease. Neuromodulators correct muscle-mediated skin creases, reshape the face, and address right-left functional asymmetry. Read More

J Am Acad Dermatol 2018 09;79(3):407-419

Division of Dermatology, Loyola University Medical Center, Maywood, Illinois.

Cosmetic dermatologic surgery has evolved to be a minimally invasive field that addresses patient concerns with a multimodal approach while minimizing adverse events and downtime. Within the armamentarium of dermatologic surgery, injections of soft tissue augmentation materials and neuromodulators are key tools for recontouring the aging face. Treatment of the individual patient is preceded by a comprehensive consultation that elicits patient concerns and preferences. Read More

Dermatol Surg 2018 11;44 Suppl 1:S51-S53

Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada Pacific Derm, Vancouver, British Columbia, Canada Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

J Cosmet Dermatol 2018 Aug 9. Epub 2018 Aug 9.

Department of Medical Education, Albany Medical College, Albany, New York.

Background: To investigate the effectiveness of the posterior temporal supraSMAS minimally invasive lifting technique and compared it to experiments performed in fresh human body donors by applying skin vector displacement measurement technology.

Materials And Methods: A total of 15 patients (14 females/1 male) with a mean age of 37.1 ± 9. Read More

J Cosmet Laser Ther 2018 Aug 1:1-5. Epub 2018 Aug 1.

c Department of Medical Device Management and Research , SAIHST, Sungkyunkwan University , Seoul 06351 , Korea.

Background: Hyaluronic acid fillers have become popular soft tissue filler augmentation agents over the past several years. Q.O. Read More

J Clin Aesthet Dermatol 2018 Jul 1;11(7):40-43. Epub 2018 Jul 1.

Dr. Werschler are with Yardley Dermatology Associates in Yardley, Pennsylvania.

Facial volume loss can substantially impact self-perception of the affected individual and his to her social/professional interactions and opportunities. Persons who are perceived as more youthful and attractive are rated as nicer, more energetic, healthier, and more likely to be productive than those perceived to be older and unattractive. The goal of this study was to assess the changes in emotional and functional status of subjects treated with 2 to 4 monthly PLLA injections to the upper, mid, and lower face. Read More

Clin Cosmet Investig Dermatol 2018 16;11:357-363. Epub 2018 Jul 16.

European Medical Aesthetics Ltd, London, UK.

With their high elasticity and viscosity, calcium hydroxylapatite (CaHA) fillers are now widely used to treat age-related or hereditary facial soft tissue volume deficits. CaHA filler volume augmentation is further enhanced by its ability to stimulate neocollagenesis and improve skin quality. However, its high viscosity and cohesivity may hinder its spread and distribution, while its injection by cannula or needle may require moderate extrusion force and lead to uneven distribution or focal accumulation in tissues. Read More

Semin Cutan Med Surg 2018 Jun;37(4S):S75-S84

Clinical Associate Professor Department of Dermatology University of California, Irvine School of Medicine Private Practice Santa Barbara, CA.

Updates on managing some of the most common dermatologic conditions for which patients seek care illuminated presentations at the Skin Disease Education Foundation's 42nd Annual Hawaii Dermatology Seminar®. This educational supplement summarizes the highlights of clinical sessions presented during this CME/CE conference. Treatment of psoriasis has continued to advance, with three interleukin (IL)-17 antagonists approved by the US Food and Drug Administration (FDA) and a fourth in phase 3 trials. Read More

J Cosmet Dermatol 2018 Oct 13;17(5):712-718. Epub 2018 Jul 13.

Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Hyaluronic acid (HA) injection is a popular nonsurgical, facial rejuvenating procedure. Due to the rapidly expanding use of HA injections, significant potential complications have also increased in frequency. Among these complications, the rare but most devastating one is arterial occlusion, which can result in skin necrosis or blindness. Read More

Facial Plast Surg Clin North Am 2018 Aug;26(3):323-330

Beup Aesthetic Plastic Surgery Clinic, Seoul, Republic of Korea. Electronic address:

Rhinoplasty is a commonly performed cosmetic surgery in Asia. Rhinoplasty using filler is preferred because has fewer side effects and shorter down time. The part of external nose between the skin and bone or cartilages consists of 4 layers. Read More

Am J Case Rep 2018 Jul 13;19:825-828. Epub 2018 Jul 13.

Department of Radiology, Universiti Kebangsaan Malaysia Medical Center, Cheras, Malaysia.

BACKGROUND Dermal fillers are increasingly used for medical and aesthetic purposes in clinical practice. Common complications following filler injections include bruising, itching, infections, allergic reactions, and tissue necrosis. This case is the first report of Herpes simplex virus type 1 (HSV-1) encephalitis as a possible complication of dermal filler injection. Read More

Dermatol Surg 2019 Jan;45(1):108-116

CIDGE International Dermatology Clinic, Geneva, Switzerland.

Background: Hyaluronic acid (HA) fillers are the preferred injectable products for aesthetic correction of skin depressions and restoration of facial volume.

Objective: To investigate the subcutaneous distribution of 3, biophysically distinct, CE-marked and FDA-approved HA fillers.

Materials And Methods: BELB, JUVV, and RESL were injected ex vivo in porcine and human skin. Read More

Plast Reconstr Surg 2018 07;142(1):112-121

Tokyo and Kawasaki, Japan From the Departments of Plastic, Oral and Maxillofacial Surgery and Plastic Surgery, Teikyo University School of Medicine; and University Hospital, Mizonokuchi.

Background: Because subcutaneously injected hyaluronic acid filler is absorbed over 6 months to 1 year after the treatment of facial wrinkles, frequent retreatment may be required. However, persistent long-term effects are often clinically observed when hyaluronic acid filler is injected as a bolus for facial augmentation. Therefore, the authors investigated, over time, the changes in volume and histologic features of subcutaneous bolus injections of hyaluronic acid. Read More

Aesthetic Plast Surg 2018 Oct 11;42(5):1388-1392. Epub 2018 Jun 11.

King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

Background: The widespread desire to maintain youth and beauty with minimally invasive procedures made the use of soft tissue fillers an attractive option to correct numerous aesthetic problems. However, many complications have emerged recently especially with the use of non-FDA-approved permanent materials. In this case report, we are demonstrating the effective management of a patient with Brucella isolated from a facial abscess at the site of prior permanent filler injection done 17 years ago. Read More

Aesthetic Plast Surg 2018 Aug 11;42(4):1119-1125. Epub 2018 Jun 11.

Universitätsklinikum Magdeburg Universitätsklinik für Psychosomatische Medizin und Psychotherapie [University Hospital for Psychosomatic Medicine and Psychotherapy], Leipziger Straße 44, Eschenstr. 5, Magdeburg, 39120, Germany.

Background: The demand for minimally invasive cosmetic procedures has continued to rise, especially in Germany, yet few studies have examined this patient population. The literature in Germany has repeatedly voiced the speculation that users of minimally invasive, skin-rejuvenating procedures displayed a higher tendency toward dysmorphic behavior patterns or, respectively, other abnormal personality traits.

Objectives: The aim of this study was to investigate body image, personality traits, quality of life, and socioeconomic parameters in users of botulinum toxin and/or facial fillers. Read More

Acta Dermatovenerol Alp Pannonica Adriat 2018 Jun;27(2):71-73

Department of Dermatology, School of Medicine, Ankara, Turkey.

Introduction: Lip augmentation procedures with hyaluronic acid dermal fillers have become increasingly popular worldwide because full lips are often considered beautiful and youthful. The goal of a lip augmentation procedure is to create smooth lips with adequate volume and a natural appearance. Various techniques for lip augmentation have been utilized and described. Read More

Plast Reconstr Surg Glob Open 2018 May 25;6(5):e1789. Epub 2018 May 25.

Anticlock Clinic, Chandigarh and Department of Plastic surgery, Fortis Hospital, Mohali, India.

Hyaluronic acid dermal fillers are becoming popular all over the world, but due to the presence of many blood vessels in the face, there is always a small possibility of vascular complications. We present a case with the ischemic involvement of chin and neck skin after accidental submental artery involvement after hyaluronic acid filler injection for chin region. Impending skin necrosis on the chin and upper neck on the right side was diagnosed quickly by observing the skin changes in the immediate postfiller phase. Read More

Aesthet Surg J 2018 Apr;38(suppl_1):S24-S28

Department of Dermatology, Icahn School of Medicine at Mt. Sinai, New York, NY.

The recent approval in 2015 of Radiesse for injection into the hand by the FDA has spurred an increase in interest among patients and clinicians in nonsurgical hand rejuvenation using fillers. Application of the same techniques used to treat the face to the dorsum of the hands does not account for the unique nature of the skin and underlying anatomy, and can lead to suboptimal outcomes and an increased risk of adverse events such as the formation of nodules. Here, the authors discuss dilution strategies and injection techniques for hand rejuvenation using Radiesse for optimal patient safety and aesthetic outcomes. Read More

Plast Reconstr Surg 2018 09;142(3):273e-280e

Seoul, Republic of Korea; and Bangkok, Thailand From the Division of Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institution, BK21 PLUS Project, Yonsei University College of Dentistry; and the Chula Soft Cadaver Surgical Training Center and Department of Anatomy, Faculty of Medicine, Chulalongkorn University.

Background: Understanding the topography of the blood vessels distributed around the nasolabial fold region is essential for ensuring the safety of dermal filler injections into the nasolabial fold. The purpose of this study was to provide anatomical information on the infraorbital artery distribution and its relationship with the facial artery for use in clinical procedures involving filler injection during nasolabial fold augmentation.

Methods: The infraorbital artery was investigated in the nasolabial fold region divided into zones I to XII based on clock-hour meridians centered on the infraorbital foramen. Read More

Plast Reconstr Surg Glob Open 2018 Apr 20;6(4):e1776. Epub 2018 Apr 20.

Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pa.

Hyaluronic acid (HA) is present in the connective tissues of the skin and decreases with age. HA fillers are popular as facial rejuvenation treatments. They are generally considered safe; however, complications, such as cutaneous necrosis and blindness due to vascular embolism, sometimes occur. Read More

Facial Plast Surg 2018 Jun 1;34(3):270-277. Epub 2018 Jun 1.

Associate Professor, Department of Otolaryngology, Division of Facial Plastic Surgery, Johns Hopkins Hospital, Baltimore, Maryland.

Rhinoplasty surgery is known to have revision rates up to 20%. Surgical revisions include the risk of anesthesia and scarring. The skilled injector may offer nonsurgical alternatives to patients when considering revision surgery. Read More

Hautarzt 2018 Jun;69(6):491-509

Hautzentrum Köln, Schillingsrotter Str. 39-41, 50996, Köln, Deutschland.

Hyaluronic acid based fillers (HA fillers) are the most frequently used soft-tissue fillers. They have a favorable benefit-risk ratio compared to other fillers and they can usually be dissolved using hyaluronidase. The anatomical area to be injected contributes to filler selection. Read More

Aesthet Surg J 2018 May 28. Epub 2018 May 28.

Division of Facial Plastic Surgery, Department of Otorhinolaryngology, Head and Neck Surgery, McGovern Medical School, University of Texas Health Science Center, Houston, TX.

Background: The midface is particularly prone to the senescent changes of soft tissue ptosis and volume loss, which in individuals with aging or low adiposity can manifest as submalar hollowing. Facelift alone in those with submalar hollowing inadequately addresses the volume loss and may result in a gaunt appearance postoperatively. Submalar implant augmentation is a powerful tool for permanent midface volume restoration for a more youthful and natural contour, as opposed to soft tissue fillers that diminish over time. Read More

Dermatol Surg 2018 06;44(6):833-840

Galderma Laboratories, L.P., Fort Worth, Texas.

Background: Injectable fillers, such as those containing hyaluronic acid (HA), are increasingly used to smooth age-related facial creases and wrinkles.

Objective: To compare efficacy and safety of a HA gel with lidocaine formulated by XpresHAn Technology (HARDL) with a HA gel without lidocaine produced by Hylacross technology (HAJUP) in the treatment of moderate-to-severe nasolabial folds.

Materials And Methods: Subjects (n = 162) received initial and touch-up injections with HARDL and HAJUP on either side of the face. Read More

Dermatol Surg 2018 Jun;44(6):826-832

Department of Dermatology, Klinikum Darmstadt, Darmstadt, Germany.

Background: Hyaluronic acid (HA) fillers are commonly used in treating facial wrinkles and folds but have not been studied with standardized methodology to include assessment of standard facial expressions.

Objective: To assess perceived naturalness of facial expression after treatment with 2 HA fillers manufactured with XpresHAn Technology (also known as Optimal Balance Technology).

Materials And Methods: Treatment was directed to the nasolabial folds (NLFs) and at least 1 additional lower face wrinkle or fold. Read More

Aesthetic Plast Surg 2018 May 14. Epub 2018 May 14.

AC Aesthetic Clinic, London, England, UK.

Introduction: The emergence of hyaluronic acid dermal fillers with lidocaine has transformed the minimally invasive treatment of wrinkles, lines and folds of the face. Patients can be treated quickly, painlessly and without the need for large doses of lidocaine. Therefore, it is important to scientifically evaluate the merits of lidocaine-containing products over those without. Read More

Plast Reconstr Surg 2018 06;141(6):1351-1359

Munich, Germany; Salzburg, Austria; Sacramento, Calif.; Albany, N.Y.; and Zurich, Switzerland From the Department of Hand, Plastic and Aesthetic Surgery, Ludwig-Maximilians University; the Department of Radiology, Paracelsus Medical University Salzburg and Nuremberg; the Department of Cell Biology and Physiology, University of Salzburg, the Department of Facial Plastic Surgery, University of California-Davis Medical Center; the Department of Medical Education, Albany Medical College; and the Division of Thoracic Surgery, University Hospital Zurich.

Background: The superficial (subcutaneous) facial fat compartments contribute to the signs of facial aging, but a comprehensive anatomical description of their location and their functional behavior during the application of soft-tissue fillers remains elusive.

Methods: The authors investigated 30 fresh frozen cephalic specimens from 13 male and 17 female Caucasian body donors (age, 78.3 ± 14. Read More

Plast Reconstr Surg 2018 06;141(6):818e-830e

Parkville, Victoria, Australia From the Taylor Lab, Department of Anatomy and Neuroscience, University of Melbourne; and the Department of Plastic and Reconstructive Surgery, The Royal Melbourne Hospital.

Background: Most target areas for facial volumization procedures relate to the anatomical location of the facial or ophthalmic artery. Occasionally, inadvertent injection of hyaluronic acid filler into the arterial circulation occurs and, unrecognized, is irreparably associated with disastrous vascular complications. Of note, the site of complications, irrespective of the injection site, is similar, and falls into only five areas of the face, all within the functional angiosome of the facial or ophthalmic artery. Read More

J Drugs Dermatol 2018 May;17(5):580-581

Nodule formation can be a potentially disfiguring adverse event of soft tissue fillers. Limited treatment consensus exists regarding the optimal approach for addressing recurrent and persistent nodules. Here we describe two challenging cases of nodules that developed following injection with Restylane and Juvéderm Voluma. Read More

Gerodontology 2018 Jun;35(2):151-154

Oral Medicine, Oral Surgery and Implantology Unit, Faculty of Medicine and Odontology, University of Santiago de Compostela, Santiago de Compostela, Spain.

Objective: To report conservative treatment based on the use of dermal fillers for a case of recurrent angular cheilitis.

Case Report: An 80-year-old patient with a history of recurrent angular cheilitis that was not resolved with a conventional approach sought treatment. Complete remission of the pathology was achieved with the injection of hyaluronic acid fillers. Read More