142 results match your criteria Injectable Bulking Agents for Incontinence


Injection of Urethral Bulking Agents.

Urol Clin North Am 2019 Feb;46(1):1-15

Urinary Tract and Pelvic Reconstruction, Department of Urology, MD Anderson Cancer Center, Unit 1373, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Electronic address:

Urethral injection is a safe and minimally invasive method of treating female stress urinary incontinence with multiple bulking agents currently commercially available. Although there are numerous studies that demonstrate efficacy, long-term success is not yet proven. This article aims to describe the mechanism of action and properties of various agents, patient selection factors, available techniques for injection, outcomes of urethral injections, and complications associated with the procedure. Read More

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http://dx.doi.org/10.1016/j.ucl.2018.08.012DOI Listing
February 2019
22 Reads

Can Urethral Bulking Agents Salvage Failed Slings?

Urology 2019 Feb 7;124:78-82. Epub 2018 Nov 7.

Michigan Medicine University of Michigan, Ann Arbor, MI.

Objective: To evaluate the efficacy of urethral bulking agents for stress urinary incontinence (SUI) in the setting of prior failed sling.

Methods: This is a retrospective review of patients who underwent urethral bulking agent injections for a primary complaint of SUI following prior failed sling surgery. The outcomes assessed were patient reported improvement, need for further interventions for incontinence and validated questionnaires. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00904295183105
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http://dx.doi.org/10.1016/j.urology.2018.09.019DOI Listing
February 2019
13 Reads

Retrospective analysis after endoscopic urethral injections of glutaraldehyde-cross-linked-collagen or dextranomer/hyaluronic acid copolymer in bitches with urinary incontinence.

J Small Anim Pract 2019 Feb 2;60(2):96-101. Epub 2018 Nov 2.

EVIDENSIA Tierärztliche Klinik für Kleintiere Norderstedt GmbH, 22850 Norderstedt, Germany.

Objectives: To evaluate the outcome of endoscopic injection of two different bulking agents, glutaraldehyde cross-linked collagen and dextranomer/hyaluronic acid copolymer into the urethral submucosa in female dogs with urinary incontinence caused by urethral sphincter mechanism incompetence.

Materials And Methods: Retrospective review of records and follow-up communication with owners of dogs that received an endoscopically guided urethral bulking procedure. In each dog, either cross-linked collagen (2007 to 2011) or dextranomer/hyaluronic acid copolymer (2012 to 2015) was used. Read More

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http://doi.wiley.com/10.1111/jsap.12949
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http://dx.doi.org/10.1111/jsap.12949DOI Listing
February 2019
8 Reads

Efficacy and safety of polydimethylsiloxane injection (Macroplastique ) for the treatment of female stress urinary incontinence: results of a series of 85 patients with ≥3 years of follow-up.

BJU Int 2019 Feb 16;123(2):353-359. Epub 2018 Oct 16.

Department of Obstetrics and Gynecology, University of Insubria, Varese, Italy.

Objective: To assess the long-term efficacy and safety of polydimethylsiloxane injection (Macroplastique , Cogentix Medical, Orangeburg, New York, USA) for the treatment of female stress urinary incontinence (SUI), with a minimum follow-up of 3 years.

Patients And Methods: This is an observational analytical prospective cohort study conducted in a single uro-gynaecological unit. All consecutive women with urodynamically confirmed pure SUI treated with the Macroplastique procedure, were included. Read More

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http://doi.wiley.com/10.1111/bju.14550
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http://dx.doi.org/10.1111/bju.14550DOI Listing
February 2019
11 Reads

Urolastic®, a new bulking agent for treatment of stress urinary incontinence: a systematic review and meta-analysis.

Int Urogynecol J 2018 09 23;29(9):1239-1247. Epub 2018 Jun 23.

Clinical Epidemiology and Medical Statistics Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Viale San Pietro 12, 07100, Sassari, Italy.

Introduction And Hypothesis: The aim of the present systematic review and meta-analysis was to assess the effectiveness and safety of injections of the new bulking agent Urolastic® in the treatment of patients with stress urinary incontinence (SUI).

Methods: A systematic search was carried out to select observational and experimental studies on Urolastic® in female patients with SUI. Three different databases, Pubmed, the Cochrane Central Register of Controlled Trials, and Scopus, were used to retrieve scientific articles published from their inception to 31 January 2018. Read More

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http://dx.doi.org/10.1007/s00192-018-3703-6DOI Listing
September 2018
20 Reads

CT and MR Imaging Features of Artificial Urinary Sphincters, Penile Prostheses, and Other Devices in the Male Lower Genitourinary Tract.

Radiographics 2018 May-Jun;38(3):794-805

From PENRAD Imaging and Colorado Springs Radiologists, Colorado Springs, Colo (E.T.C.); and Departments of Radiology (P.R., E.S.S.) and Urology (W.I.J.), Hospital of the University of Pennsylvania, 3400 Spruce St, MRI 1 Founders, Philadelphia, PA 19104-4283.

Urinary incontinence and erectile dysfunction are relatively common conditions in the aging male population. Surgical interventions for urinary incontinence include placement of an artificial urinary sphincter (AUS), perineal sling, or sacral nerve stimulator and injections of periurethral bulking agents. Erectile dysfunction can be treated surgically with placement of a penile prosthesis. Read More

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http://pubs.rsna.org/doi/10.1148/rg.2018170087
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http://dx.doi.org/10.1148/rg.2018170087DOI Listing
October 2018
19 Reads

Face, Content, and Construct Validations of Endoscopic Needle Injection Simulator for Transurethral Bulking Agent in Treatment of Stress Urinary Incontinence.

J Surg Educ 2018 Nov 3;75(6):1673-1678. Epub 2018 May 3.

Department of Urology, Division of Female Urology, Pelvic Reconstruction Surgery & Voiding Dysfunction University of California, Irvine, California. Electronic address:

Introduction And Objectives: Endoscopic injection of urethral bulking agents is an office procedure that is used to treat stress urinary incontinence secondary to internal sphincteric deficiency. Validation studies important part of simulator evaluation and is considered important step to establish the effectiveness of simulation-based training. The endoscopic needle injection (ENI) simulator has not been formally validated, although it has been used widely at University of California, Irvine. Read More

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http://dx.doi.org/10.1016/j.jsurg.2018.04.011DOI Listing
November 2018
3 Reads

Achieving urinary continence in cloacal exstrophy: The surgical cost.

J Pediatr Surg 2018 Oct 24;53(10):1937-1941. Epub 2018 Feb 24.

Robert D. Jeffs Division of Pediatric Urology, The James Buchanan Brady Urological Institutions, The Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Charlotte Bloomberg Children's Hospital, Baltimore, MD, USA. Electronic address:

Introduction: Cloacal exstrophy (CE) is a severe midline congenital abnormality that requires numerous surgical corrections to achieve an acceptable quality of life. Candidates for urinary continence undergo multiple procedures, most often continent bladder diversions, to become socially dry. Here, the authors investigate the number of genitourinary interventions that patients with CE undergo to attain urinary continence. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.02.055DOI Listing
October 2018
5 Reads

Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment.

Acta Biomater 2018 02 29;67:156-166. Epub 2017 Nov 29.

Laboratory of Stem Cell Bioengineering, Institute of Bioengineering, School of Life Sciences and School of Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

Endoscopic injection of bulking agents has been widely used to treat urinary incontinence, often due to urethral sphincter complex insufficiency. The aim of the study was to develop a novel injectable bioactive collagen-fibrin bulking agent restoring long-term continence by functional muscle tissue regeneration. Fibrin micro-beads were engineered using a droplet microfluidic system. Read More

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http://dx.doi.org/10.1016/j.actbio.2017.11.034DOI Listing
February 2018
6 Reads

Effectiveness of Bulking Agent (Solesta) Therapy in Fecal Incontinence in Patients Refractory to Conventional Therapies.

Am J Med Sci 2017 11 5;354(5):476-479. Epub 2017 Sep 5.

Division of Gastroenterology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine, El Paso, Texas. Electronic address:

Background: Fecal incontinence is a problem that imposes considerable socioeconomic consequences. Despite many medical therapies, unmet needs remain. A new treatment option is a biocompatible bulking agent (Solesta) administered by submucosal injection in the distal rectum. Read More

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http://dx.doi.org/10.1016/j.amjms.2017.09.001DOI Listing
November 2017
11 Reads

Complications of Urethral Bulking Agents for Stress Urinary Incontinence: An Extensive Review Including Case Reports.

Female Pelvic Med Reconstr Surg 2018 Nov/Dec;24(6):392-398

Department of Urology, University of Illinois, Chicago, IL.

Objectives: Stress urinary incontinence in women is a common problem that significantly impacts quality of life. Periurethral injection of urethral bulking agents (UBAs) is a simple, noninvasive, and cost-effective treatment. However, complications associated with UBA are often underappreciated. Read More

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http://dx.doi.org/10.1097/SPV.0000000000000495DOI Listing
April 2019
3 Reads

Aktuelle Behandlungskonzepte bei Belastungsinkontinenz.

Praxis (Bern 1994) 2017 Jul;106(15):829-836

1 Blasen- und Beckenbodenzentrum, Frauenklinik, Kantonsspital Frauenfeld.

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http://dx.doi.org/10.1024/1661-8157/a002743DOI Listing
July 2017
15 Reads

Urethral injection therapy for urinary incontinence in women.

Cochrane Database Syst Rev 2017 07 25;7:CD003881. Epub 2017 Jul 25.

Department of Urology, Sunderland Royal Hospital, Kayll Road, Sunderland, Tyne & Wear, UK, SR4 7TP.

Background: Urinary incontinence imposes a significant health and economic burden to society. Periurethral or transurethral injection of bulking agents is a minimally invasive surgical procedure used as one the surgical treatments of stress urinary incontinence (SUI) in adult women.

Objectives: To assess the effects of periurethral or transurethral injection therapy on the cure or improvement of urinary incontinence in women. Read More

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http://dx.doi.org/10.1002/14651858.CD003881.pub4DOI Listing
July 2017
13 Reads

Radiographic Misdiagnoses After Periurethral Bulking Agents.

Female Pelvic Med Reconstr Surg 2018 Jul/Aug;24(4):312-314

William Beaumont School of Medicine, Oakland University, Rochester, MI.

Objectives: Injectable urethral bulking agents are commonly used to manage stress urinary incontinence. Urologic or other symptoms may prompt pelvic imaging at a later date, when bulking agents may be visualized and incorrectly interpreted. Our goal was to evaluate the incidence of misdiagnosis and which pathologies were the most common misinterpretations and their frequency. Read More

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http://dx.doi.org/10.1097/SPV.0000000000000440DOI Listing
March 2019
51 Reads

Periurethral bulking agents for female stress urinary incontinence in Canada.

Can Urol Assoc J 2017 Jun;11(6Suppl2):S152-S154

Section of Urology, Department of Surgery, University of Calgary, Calgary, AB, Canada.

Urethral bulking aims to improve urethral mucosal coaptation, and thus outlet resistance, in an effort to limit stress-induced leakage. While efforts have been made to employ bulking agents to treat stress urinary incontinence (SUI) for more than 100 years, we remain wanting for the perfect injectable. Regardless of the agent studied, efficacy is modest at best, repeat injections are the norm, and long-term followup is conspicuously lacking. Read More

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http://www.cuaj.ca/index.php/journal/article/view/4612
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http://dx.doi.org/10.5489/cuaj.4612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461150PMC
June 2017
40 Reads

Management of patients with stress urinary incontinence after failed midurethral sling.

Can Urol Assoc J 2017 Jun;11(6Suppl2):S143-S146

Department of Urology, Dalhousie University, Halifax, NS; Canada.

Surgical failure rates after midurethral sling (MUS) procedures are variable and range from approximately 8-57% at five years of followup. The disparity in long-term failure rates is explained by a lack of long-term followup and lack of a clear definition of what constitutes failure. A recent Cochrane review illustrates that no high-quality data exists to recommend or refute any of the different management strategies for recurrent or persistent stress urinary incontinence (SUI) after failed MUS surgery. Read More

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http://dx.doi.org/10.5489/cuaj.4610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461148PMC
June 2017
13 Reads

Midterm outcomes of injectable bulking agents for fecal incontinence: a systematic review and meta-analysis.

Tech Coloproctol 2017 Mar 1;21(3):203-210. Epub 2017 Mar 1.

Department of Colorectal Surgery, Korea University College of Medicine Ansan Hospital, Gojan 1-dong, Danwon-gu, Ansan-si, Gyeonggi-do, Republic of Korea.

Background: Various bulking agents have been used to treat fecal incontinence. While short-term outcomes are attractive, there is still a lack of long-term data. The aim of this systematic review and meta-analysis was to investigate the midterm outcomes of treatment with injectable bulking agents and to identify predictive factors for improvement in incontinence. Read More

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http://dx.doi.org/10.1007/s10151-017-1593-0DOI Listing
March 2017
1 Read

Intraurethral bulking agents for the management of female stress urinary incontinence: a systematic review.

Int Urogynecol J 2017 Sep 21;28(9):1275-1284. Epub 2017 Feb 21.

Department of Urology, Watford General Hospital, Vicarage Road, Watford, WD80 0HB, UK.

Introduction And Hypothesis: The object of this review was to assess the efficacy and safety of urethral bulking agents (UBA), principally Macroplastique and Bulkamid, in the treatment of female stress urinary incontinence (SUI).

Methods: MEDLINE® and EMBASE® databases were systematically searched up to June 2016. Year of publication, study type, outcome measures, urodynamics before and after the procedure, number of participants, procedure complications, proportion requiring repeat injections or surgical procedures, frequency of follow-up, and results were analysed. Read More

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http://dx.doi.org/10.1007/s00192-017-3278-7DOI Listing
September 2017
2 Reads

Sacral neuromodulation compared with injection of bulking agents for faecal incontinence following obstetric anal sphincter injury - a randomized controlled trial.

Colorectal Dis 2017 May;19(5):O134-O144

Department of Gastroenterological Surgery, University Hospital of North Norway, Tromsoe, Norway.

Aim: The purpose of this trial was to compare the effectiveness of sacral neuromodulation (SNM) with a submucosal injection of collagen (Permacol®) in women with faecal incontinence following obstetric anal sphincter injury (OASIS).

Method: This single-blinded randomized controlled trial at two hospital units in Norway included women with faecal incontinence following OASIS. Eligible women who had had a successful percutaneous nerve evaluation were randomly assigned to SNM or Permacol®. Read More

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http://dx.doi.org/10.1111/codi.13632DOI Listing
May 2017
7 Reads

Para-Urethral Injections with Urolastic® for Treatment of Female Stress Urinary Incontinence: Subjective Improvement and Safety.

Urol Int 2017 3;99(1):91-97. Epub 2017 Feb 3.

Department of Urology, Radboud University Medical Centre, Nijmegen, The Netherlands.

Introduction: Female stress urinary incontinence (SUI) is often treated surgically. Urethral bulking agents are a minimally invasive alternative, especially in patients suffering from intrinsic sphincter deficiency, but often with limited long-term efficacy. Urolastic® is a non-deformable, non-resorbable silicone elastomer that is used as an injectable. Read More

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http://dx.doi.org/10.1159/000452450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637293PMC
May 2018
17 Reads

Nonabsorbable urethral bulking agent - clinical effectiveness and late complications rates in the treatment of recurrent stress urinary incontinence after 2 years of follow-up.

Eur J Obstet Gynecol Reprod Biol 2016 Dec 26;207:68-72. Epub 2016 Oct 26.

2nd Department of Gynecology, Medical University of Lublin, ul. Jaczewskiego 8, 20-954 Lublin, Poland.

Objective: Those patients who failed to achieve continence after a procedure aimed to correct it, require a special attitude and precise management due to the sophisticated anatomical and functional field of interest. The purpose of the present study was to assess long-term clinical efficacy and evaluate the frequency and severity of any complications related to recurrent stress urinary incontinence treatment with a non-absorbable bulking agent periurethral injections.

Study Design: Between February 2012-September 2013, 66 patients with recurrent stress urinary incontinence were treated with Urolastic in the tertiary referral gynecologic department. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2016.10.011DOI Listing
December 2016
14 Reads

Outcomes of Surgical Management in Patients with Stress Urinary Incontinence and/or Neovesicovaginal Fistula after Orthotopic Neobladder Diversion.

J Urol 2016 11 8;196(5):1478-1483. Epub 2016 Jun 8.

Department of Urology, Mayo Clinic, Rochester, Minnesota. Electronic address:

Purpose: To our knowledge there are no guidelines for the evaluation and management of incontinence in women with an orthotopic neobladder. We propose a treatment algorithm based on our experience with treating this patient population.

Materials And Methods: We identified women in whom orthotopic neobladder diversion and surgery for incontinence were performed from January 1, 1995 to January 1, 2014. Read More

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http://dx.doi.org/10.1016/j.juro.2016.06.009DOI Listing
November 2016
21 Reads

The efficacy and safety of urethral injection therapy for urinary incontinence in women: a systematic review.

Clinics (Sao Paulo) 2016 Feb;71(2):94-100

Disciplina de Ginecologia, Divisão de Uroginecologia, Departamento de Obstetrícia e Ginecologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo/SP, Brazil.

To evaluate the efficacy and safety of different bulking agents for treating urinary incontinence in women, a systematic review including only randomized controlled trials was performed. The subjects were women with urinary incontinence. The primary outcomes were clinical and urodynamic parameters. Read More

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http://dx.doi.org/10.6061/clinics/2016(02)08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760362PMC
February 2016
10 Reads

Transanal submucosal polyacrylamide gel injection treatment of anal incontinence: a randomized controlled trial.

Acta Obstet Gynecol Scand 2016 May 14;95(5):528-33. Epub 2016 Mar 14.

Department of Clinical Sciences, Karolinska Institute Danderyd Hospital, Danderyd, Sweden.

Introduction: The efficacious and safe use of transurethral injections of polyacrylamide hydrogel (Bulkamid(®)) in women with stress urinary incontinence suggests that it may be suitable also for treatment of anal incontinence. We aimed to determine the effectiveness and safety of polyacrylamide hydrogel when used as a transanal submucosal bulking agent in women with anal incontinence.

Materials And Methods: Thirty women with a diagnosis of anal incontinence and a Cleveland Clinic Incontinence Score (CCIS) >10 were randomized to three different techniques of transanal submucosal injections using polyacrylamide hydrogel. Read More

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http://dx.doi.org/10.1111/aogs.12866DOI Listing
May 2016
9 Reads

Bulking agents - an analysis of 500 cases and review of the literature.

Clin Exp Obstet Gynecol 2016;43(5):666-672

Introduction: Stress urinary incontinence (SUI) is common, impacts women's quality of life and generates high costs. Physiotherapy is the first line therapy and if it fails, suburethral slings are currently the gold standard in SUI surgery. Bulking agents injected periurethrally might be a beneficial alternative, but there is a paucity of data on bulking therapy. Read More

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September 2018
5 Reads

Trends in surgical management and pre-operative urodynamics in female medicare beneficiaries with mixed incontinence.

Neurourol Urodyn 2017 02 17;36(2):422-425. Epub 2015 Dec 17.

Department of Healthcare Policy and Research, New York-Presbyterian Hospital, Weill Medical College of Cornell University, New York, New York.

Objective: We sought to examine the surgical trends and utilization of treatment for mixed urinary incontinence among female Medicare beneficiaries.

Methods: Data was obtained from a 5% national random sample of outpatient and carrier claims from 2000 to 2011. Included were female patients 65 and older, diagnosed with mixed urinary incontinence, who underwent surgical treatment identified by Current Procedural Terminology, Fourth Edition (CPT-4) codes. Read More

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http://dx.doi.org/10.1002/nau.22946DOI Listing
February 2017
14 Reads

Current interventional management of male stress urinary incontinence following urological procedures.

Cent European J Urol 2015 26;68(3):340-7. Epub 2015 Sep 26.

Department of Urology, Collegium Medicum at the Jagiellonian University, Cracow, Poland.

Introduction: Despite improvements in surgical techniques and implementation of minimally invasive procedures, male stress urinary incontinence affects a substantial number of patients after prostatic surgery. In response to increasing demand of optimal treatment modality, new alternatives to artificial urinary sphincter have recently been introduced. This review summarises the therapeutic surgical options with their outcomes in management of postprostatectomy stress incontinence. Read More

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http://www.termedia.pl/Journal/-57/pdf-25862-10?filename=17.
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http://www.termedia.pl/Current-interventional-management-of-
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http://dx.doi.org/10.5173/ceju.2015.616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643709PMC
November 2015
9 Reads

Polyacrylamide hydrogel (Bulkamid®) for stress urinary incontinence in women: a systematic review of the literature.

Int Urogynecol J 2016 Mar 26;27(3):367-75. Epub 2015 Jul 26.

Department of Obstetrics and Gynaecology, Urogynaecology Unit, St. George's University Hospitals NHS Foundation Trust, London, SW17 0QT, UK.

Introduction And Hypothesis: Polyacrylamide hydrogel (PAHG, Bulkamid®) is one of several injectable agents currently used for the treatment of women with urinary stress incontinence. Although bulking agents appear to have lower efficacy rates compared to other surgical treatments, current evidence based on large prospective or comparative studies as well as systematic reviews is limited. The purpose of this study was to conduct a systematic review on the efficacy of PAHG in the treatment of female patients with stress urinary incontinence with regard to reproducibility, feasibility, safety and clinical outcome. Read More

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http://link.springer.com/10.1007/s00192-015-2781-y
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http://dx.doi.org/10.1007/s00192-015-2781-yDOI Listing
March 2016
11 Reads

An Open Multicenter Study of Clinical Efficacy and Safety of Urolastic, an Injectable Implant for the Treatment of Stress Urinary Incontinence: One-Year Observation.

Biomed Res Int 2015 20;2015:851823. Epub 2015 Apr 20.

2nd Department of Gynecology, Medical University of Lublin, Ulica Jaczewskiego 8, 20-954 Lublin, Poland.

The prevalence of stress urinary incontinence rises and affects up to 30% of women after 50 years of age. Midurethral slings are currently the mainstay of surgical anti-incontinence therapy. Some patients experience recurrent SUI (RSUI) which is defined as a failure of anti-incontinence surgery after a period of time or persistence of SUI after the procedure aimed at correcting it. Read More

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http://www.hindawi.com/journals/bmri/2015/851823/
Publisher Site
http://dx.doi.org/10.1155/2015/851823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461699PMC
March 2016
13 Reads

[Bulking agents in the treatment of the stress urinary incontinence - current state and future perspectives].

Ceska Gynekol 2015 Mar;80(2):156-60

A review focused on minimally invasive treatment of the stress urinary incontinence using bulking agents provides a summary of the current knowledge on this subjects. This paper summarizes the findings on the mechanism of action, indications and applications technique, as well as clinical data on the efficacy and safety of the currently available bulking agents. Attention is also paid to possible future trends of this method. Read More

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March 2015
3 Reads

Urethral bulking agents versus other surgical procedures for the treatment of female stress urinary incontinence: a systematic review and meta-analysis.

Eur J Obstet Gynecol Reprod Biol 2015 Jun 28;189:48-54. Epub 2015 Mar 28.

Department of Obstetrics and Gynaecology, University of Insubria, Varese, Italy. Electronic address:

Bulking agents provide an alternative option in the management of women with stress urinary incontinence and they seem to have an important role in the management flow chart of SUI. However, evidence on this issue is scanty. The most important aspect is to understand whether bulking agents are comparable with the other first-line anti-incontinence surgical procedure (MUS, Burch colposuspension and pubovaginal slings). Read More

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http://dx.doi.org/10.1016/j.ejogrb.2015.03.025DOI Listing
June 2015
43 Reads
1.627 Impact Factor

Collagenoma and voiding dysfunction as complications of periurethral bulking.

Int Urogynecol J 2015 Jul 10;26(7):1077-8. Epub 2015 Mar 10.

McGill University Health Centre, sponsored scholarship by King Fahad Medical City, Riyadh, Saudi Arabia.

Peri-urethral bulking agents are used as a management option for selected patients with stress urinary incontinence (SUI). We present a case of urinary retention and a large firm para-urethral vaginal mass as a complication of peri-urethral collagen injections 3 years before presentation. The patient was managed successfully with complete surgical resection of the mass. Read More

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http://dx.doi.org/10.1007/s00192-015-2649-1DOI Listing
July 2015
3 Reads

What's New in the Toolbox for Constipation and Fecal Incontinence?

Authors:
Yeong Yeh Lee

Front Med (Lausanne) 2014 24;1. Epub 2014 Mar 24.

School of Medical Sciences, Universiti Sains Malaysia , Kota Bharu , Malaysia ; Section of Gastroenterology and Hepatology, Department of Medicine, Medical College of Georgia, Georgia Regents University , Augusta, GA , USA.

Constipation and fecal incontinence (FI) are common complaints predominantly affecting the elderly and women. They are associated with significant morbidity and high healthcare costs. The causes are often multi-factorial and overlapping. Read More

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http://dx.doi.org/10.3389/fmed.2014.00005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335388PMC
February 2015
2 Reads

Injection devices for bulking agents in uro-gynaecology.

Arch Ital Urol Androl 2014 Sep 30;86(3):205-7. Epub 2014 Sep 30.

Urology Clinic, A.O.U.I. Verona.

Stress urinary incontinence (SUI) affects a large proportion of middle-aged and elderly women. When all conservative means are ineffective, a surgical treatment including retropubic suspension, pubovaginal and tension-free slings, is contemplated. Intra-urethral injections with bulking agents have been used as an alternative to the mentioned surgical procedures with alternate results. Read More

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http://dx.doi.org/10.4081/aiua.2014.3.205DOI Listing
September 2014
5 Reads

Comments to "perianal injectable bulking agents as treatment for faecal incontinence in adults".

Authors:
D F Altomare

Tech Coloproctol 2014 Nov 27;18(11):1139-40. Epub 2014 Sep 27.

Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy,

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http://dx.doi.org/10.1007/s10151-014-1218-9DOI Listing
November 2014
2 Reads

Current and emerging treatment options for fecal incontinence.

Authors:
Satish S C Rao

J Clin Gastroenterol 2014 Oct;48(9):752-64

Department of Medicine, Section of Gastroenterology/Hepatology, Digestive Health Center, Medical College of Georgia, Georgia Regents University, Augusta, GA.

Fecal incontinence (FI) is a multifactorial disorder that imposes considerable social and economic burdens. The aim of this article is to provide an overview of current and emerging treatment options for FI. A MEDLINE search was conducted for English-language articles related to FI prevalence, etiology, diagnosis, and treatment published from January 1, 1990 through June 1, 2013. Read More

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http://dx.doi.org/10.1097/MCG.0000000000000180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166012PMC
October 2014
5 Reads

Long-term efficacy of NASHA Dx injection therapy for treatment of fecal incontinence.

Neurogastroenterol Motil 2014 Aug 19;26(8):1087-94. Epub 2014 May 19.

Division of Colon & Rectal Surgery, University of Illinois, Chicago, IL, USA.

Background: Injectable bulking treatment for fecal incontinence (FI) is intended to expand tissue in the anal canal and prevent fecal leakage. Use of injectable bulking agents is increasing because it can be performed in an outpatient setting and with low risk for morbidity. This study evaluated the long-term (36-month) clinical effectiveness and safety of injection of non-animal stabilized hyaluronic acid/dextranomer (NASHA Dx) on FI symptoms. Read More

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http://dx.doi.org/10.1111/nmo.12360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371654PMC
August 2014
3 Reads

Endoscopic treatment of vesicoureteral reflux with non-simultaneous involuntary detrusor contraction in chronic spinal cord injury patients with neurogenic detrusor overactivity.

Urol Int 2014 12;93(4):399-402. Epub 2014 Mar 12.

Department of Urology, Hospital Nacional de Parapléjicos, Toledo, Spain.

Objective: To analyze whether it is correct to use endoscopic treatment via bulking agents of vesicoureteral reflux (VUR) seen on video urodynamics with non-simultaneous involuntary detrusor contraction in chronic spinal cord injury (SCI) patients with neurogenic detrusor overactivity (NDO).

Methods: A retrospective study was performed with a cohort of 76 patients (age 48.9 ± 14. Read More

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http://dx.doi.org/10.1159/000357440DOI Listing
August 2015
45 Reads

New treatments for fecal incontinence: update for the gastroenterologist.

Authors:
Arnold Wald

Clin Gastroenterol Hepatol 2014 Nov 15;12(11):1783-8. Epub 2014 Feb 15.

Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. Electronic address:

Fecal incontinence is one of the most emotionally devastating of all nonfatal conditions. Many patients do not respond satisfactorily to conservative measures, and there is a need for new and effective strategies when medical therapy fails. The development of sacral nerve stimulation and other forms of neuromodulation and the injection of biologically compatible substances into the anal sphincter complex have brought renewed enthusiasm for using these novel treatments in this underserved population. Read More

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http://dx.doi.org/10.1016/j.cgh.2014.02.013DOI Listing
November 2014
3 Reads

Surgical therapies for fecal incontinence.

Curr Opin Gastroenterol 2014 Jan;30(1):69-74

Beth Israel Deaconess Medical Center, Division of Colorectal Surgery, Boston, Massachusetts, USA.

Purpose Of Review: Fecal incontinence is a significant source of morbidity and decreased quality of life (QOL) for many. Until recent years, few therapies beyond medical management were available for patients. Surgical treatment of fecal incontinence has evolved from colostomy and direct repair of muscle defects to interventional techniques such as nerve stimulation and bulking agents. Read More

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http://dx.doi.org/10.1097/MOG.0000000000000029DOI Listing
January 2014
2 Reads

[Treatment of the urethral sphincter insufficiency].

Prog Urol 2013 Nov 24;23(14):1186-92. Epub 2013 Sep 24.

Service d'urologie et transplantation rénale, Aix-Marseille université, hôpital de la Conception, 147, boulevard Baille, 13005 Marseille, France. Electronic address:

The intrinsic sphincter insufficiency is a cause of stress urinary incontinence. Its definition is clinical and based on urodynamics. It is mostly met with women, in context of the post-obstetrical period or older women in a multifactorial context. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S11667087130057
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http://dx.doi.org/10.1016/j.purol.2013.08.312DOI Listing
November 2013
2 Reads

Role of urethral bulking agents in epispadias-exstrophy complex patients.

J Pediatr Urol 2014 Feb 2;10(1):176-80. Epub 2013 Sep 2.

The Johns Hopkins University School of Medicine, James Buchanan Brady Urological Institute, Division of Pediatric Urology, Charlotte Bloomberg Children's Hospital, Suite 7302, Baltimore, MD 21287, USA.

Objective: Injection of urethral bulking agents (UBA) has been used to increase bladder capacity prior to bladder neck reconstruction (BNR) or as an adjuvant therapy following BNR to improve continence. The purpose of this study was to determine the effectiveness of urethral injections in the exstrophy population.

Materials And Methods: A review was performed of patient characteristics, bladder capacity, and continence status of all patients with the exstrophy-epispadias complex who underwent injection of UBA between 1980 and 2008. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14775131130021
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http://dx.doi.org/10.1016/j.jpurol.2013.08.004DOI Listing
February 2014
16 Reads

Surgery for faecal incontinence in adults.

Cochrane Database Syst Rev 2013 Jul 2(7):CD001757. Epub 2013 Jul 2.

Surgery, Sheffield Teaching Hospitals, Sheffield S7, UK.

Background: Faecal incontinence is a debilitating problem with significant medical, social and economic implications. Treatment options include conservative, non-operative interventions (for example pelvic floor muscle training, biofeedback, drugs) and surgical procedures. A surgical procedure may be aimed at correcting an obvious mechanical defect, or augmenting a functionally deficient but structurally intact sphincter complex. Read More

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http://dx.doi.org/10.1002/14651858.CD001757.pub4DOI Listing
July 2013
8 Reads

Trends in the surgical management of stress urinary incontinence among female Medicare beneficiaries, 2002-2007.

Urology 2013 Jul 21;82(1):38-41. Epub 2013 May 21.

David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

Objective: To describe trends in the surgical management of female stress urinary incontinence (SUI) in the United States from 2002 to 2007.

Methods: As part of the Urologic Diseases of America Project, we analyzed data from a 5% national random sample of female Medicare beneficiaries aged 65 and older. Data were obtained from the Centers for Medicare and Medicaid Services carrier and outpatient files from 2002 to 2007. Read More

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http://dx.doi.org/10.1016/j.urology.2012.10.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757126PMC
July 2013
3 Reads

Injectable bulking agents for passive faecal incontinence.

Authors:
C E Koh M J Solomon

Tech Coloproctol 2013 Aug 9;17(4):343-4. Epub 2013 May 9.

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http://dx.doi.org/10.1007/s10151-013-1018-7DOI Listing
August 2013
4 Reads

Comparison of bulking agents in the treatment of fecal incontinence: a prospective randomized clinical trial.

Tech Coloproctol 2013 Oct 23;17(5):517-23. Epub 2013 Mar 23.

Hunter Colorectal Research, Newcastle Hospital Private Suites, New Lambton Heights, NSW, 2305, Australia,

Background: We sought to compare two synthetic injectable bulking agents, with known efficacy (PTQ™: a silicone biomaterial and Durasphere(®): pyrolytic carbon-coated beads), in the form of a randomised clinical trial.

Methods: Circumferential injection of either agent was performed under local anesthesia and sedation as a day-case procedure. The primary outcome measure was the Wexner incontinence scale. Read More

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http://dx.doi.org/10.1007/s10151-013-1000-4DOI Listing
October 2013
2 Reads

Perianal injectable bulking agents as treatment for faecal incontinence in adults.

Cochrane Database Syst Rev 2013 Feb 28(2):CD007959. Epub 2013 Feb 28.

Sir Alan Park’s Physiology Unit, St Mark’s Hospital, Harrow, UK.

Background: Faecal incontinence is a complex and distressing condition with significant medical and social implications. Injection of perianal bulking agents has been used to treat the symptoms of passive faecal incontinence. However, various agents have been used without a standardised technique and the supposed benefit of the treatment is largely anecdotal with a limited clinical research base. Read More

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http://dx.doi.org/10.1002/14651858.CD007959.pub3DOI Listing
February 2013
2 Reads

Injectable collagen for the treatment of fecal incontinence: long-term results.

Dis Colon Rectum 2013 Mar;56(3):354-9

The John Goligher Colorectal Unit, St James's University Hospital, Leeds, United Kingdom.

Background: Fecal incontinence is a distressing condition that is difficult to treat. Injection of bulking agents has been used to treat passive fecal incontinence. However, no long-term results are available. Read More

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https://insights.ovid.com/crossref?an=00003453-201303000-000
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http://dx.doi.org/10.1097/DCR.0b013e3182805276DOI Listing
March 2013
4 Reads

[Bladder injury during sling operation in the treatment of SUI--review of literature and case report].

Ginekol Pol 2012 Oct;83(10):784-8

II Katedra i Klinika Ginekologii Operacyjne Uniwersytetu Medycznego w Lublinie, Polska.

Introduction: Sling operations have been performed for over 15 years. In recent years these operations have become the gold standard in the treatment of stress urinary incontinence (SUI) due to their efficacy safety and low invasiveness. Approximately 4% of women will undergo a surgery for SUI in the course of their life. Read More

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October 2012
6 Reads

Long-term efficacy of dextranomer in stabilized hyaluronic acid (NASHA/Dx) for treatment of faecal incontinence.

Colorectal Dis 2013 May;15(5):569-74

Department of Colorectal and Pelvic Surgery, Rome University, Rome, Italy.

Aim: Randomized, controlled trials have demonstrated the efficacy and safety of injectable bulking agents for the treatment of faecal incontinence (FI), although the long-term outcome has not been assessed. NASHA/Dx gel, a biocompatible, nonallergenic bulking agent consisting of nonanimal stabilized hyaluronic acid and dextranomer microspheres, has demonstrated efficacy and safety for up to 12 months after treatment. The objective of this study was to evaluate the long-term efficacy and safety of NASHA/Dx, assessed 24 months after treatment. Read More

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http://dx.doi.org/10.1111/codi.12155DOI Listing
May 2013
4 Reads