40 results match your criteria Influenza Research and Treatment [Journal]

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Barriers Associated with Seasonal Influenza Vaccination among College Students.

Influenza Res Treat 2016 24;2016:4248071. Epub 2016 Mar 24.

Department of Health Sciences, California State University, Northridge, 18111 Nordhoff Street, Northridge, CA 91330-8285, USA.

Influenza can spread rapidly on college campuses because of high-density living conditions and frequent social interactions. However, seasonal influenza vaccination rates on college campuses are low. The purpose of this study is to identify barriers associated with receipt of the seasonal influenza vaccination. Read More

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http://dx.doi.org/10.1155/2016/4248071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823483PMC
April 2016
11 Reads

Serological Survey for Avian Influenza in Turkeys in Three States of Southwest Nigeria.

Influenza Res Treat 2015 17;2015:787890. Epub 2015 Nov 17.

Department of Veterinary Microbiology and Parasitology, University of Ibadan, Ibadan 20005, Nigeria.

Since the first outbreak of avian influenza (AI) in Nigeria in 2006, there has been continuous monitoring of the disease in chickens with little attention given to turkeys. As part of on-going surveillance for AI in southwest Nigeria, we used a competitive ELISA to detect anti-AI virus antibodies in 520 turkey sera obtained from poultry farms in Oyo, Osun, and Ondo states while haemagglutination inhibiting antibodies against low pathogenic AI viruses (LPAIVs) were detected using H3N8 and H5N2 subtype-specific antigens. The overall seroprevalence obtained by ELISA was 4. Read More

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http://dx.doi.org/10.1155/2015/787890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664809PMC
December 2015
9 Reads
1 Citation

Passive broad-spectrum influenza immunoprophylaxis.

Influenza Res Treat 2014 22;2014:267594. Epub 2014 Sep 22.

Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.

Influenza is a perennial problem affecting millions of people annually with the everpresent threat of devastating pandemics. Active prophylaxis by vaccination against influenza virus is currently the main countermeasure supplemented with antivirals. However, disadvantages of this strategy include the impact of antigenic drift, necessitating constant updating of vaccine strain composition, and emerging antiviral drug resistance. Read More

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http://dx.doi.org/10.1155/2014/267594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190013PMC
October 2014
4 Reads

Avian influenza surveillance in the danube delta using sentinel geese and ducks.

Influenza Res Treat 2014 25;2014:965749. Epub 2014 Mar 25.

College of Public Health and Health Professions, and Emerging Pathogens Institute, University of Florida, 101 S. Newell Dr., Suite 2150A, Gainesville, FL 32610, USA.

Highly pathogenic avian influenza (HPAI) H5N1 virus incursions from migrating birds have occurred multiple times in Romania since 2005. Beginning in September 2008 through April 2013, seasonal sentinel surveillance for avian influenza A viruses (AIVs) using domestic geese (Anser cygnoides) and ducks (Anas platyrhynchos) in the Danube Delta was established by placing 15 geese and 5 ducks at seven sites. Tracheal and cloacal swabs, and sera collections (starting in 2009) were taken monthly. Read More

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https://www.hindawi.com/archive/2014/965749/
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http://dx.doi.org/10.1155/2014/965749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984857PMC
May 2014
9 Reads

Effect of the PB2 and M Genes on the Replication of H6 Influenza Virus in Chickens.

Influenza Res Treat 2014 18;2014:547839. Epub 2014 Feb 18.

Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

H6 subtype influenza viruses are commonly isolated from wild aquatic birds. However, limited information is available regarding H6 influenza virus isolated from chickens. We compared the viral genome segment between A/chicken/Hong Kong/W312/97 (H6N1), which was able to grow in chicken trachea, and A/duck/Shantou/5540/01 (H6N2), which was isolated from wild aquatic duck, to explore the factors for effective replication in chicken. Read More

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http://www.hindawi.com/journals/irt/2014/547839/
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http://dx.doi.org/10.1155/2014/547839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948651PMC
April 2014
6 Reads

Detection and Isolation of Airborne Influenza A H3N2 Virus Using a Sioutas Personal Cascade Impactor Sampler.

Influenza Res Treat 2013 10;2013:656825. Epub 2013 Oct 10.

Department of Environmental and Global Health, College of Public Health and Health Professions, P.O. Box 100188, Gainesville, FL 32610, USA ; Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.

The air we breathe contains microorganisms that can cause infectious respiratory diseases. After two occupants of an apartment were diagnosed with influenza in February of 2013, efforts were made to detect and isolate airborne influenza virus using two different types of active air samplers: a Sioutas Personal Cascade Impactor Sampler (PCIS) and an SKC BioSampler. The PCIS collects size-fractionated particles by impaction on polytetrafluoroethylene filters, whereas the SKC BioSampler collects airborne particles in liquid media. Read More

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http://dx.doi.org/10.1155/2013/656825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810434PMC
November 2013
7 Reads

3D Molecular Modelling Study of the H7N9 RNA-Dependent RNA Polymerase as an Emerging Pharmacological Target.

Influenza Res Treat 2013 25;2013:645348. Epub 2013 Sep 25.

Bioinformatics & Medical Informatics Team, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, 11527 Athens, Greece.

Currently not much is known about the H7N9 strain, and this is the major drawback for a scientific strategy to tackle this virus. Herein, the 3D complex structure of the H7N9 RNA-dependent RNA polymerase has been established using a repertoire of molecular modelling techniques including homology modelling, molecular docking, and molecular dynamics simulations. Strikingly, it was found that the oligonucleotide cleft and tunnel in the H7N9 RNA-dependent RNA polymerase are structurally very similar to the corresponding region on the hepatitis C virus RNA-dependent RNA polymerase crystal structure. Read More

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http://dx.doi.org/10.1155/2013/645348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800656PMC
November 2013
19 Reads

Comparative serological assays for the study of h5 and h7 avian influenza viruses.

Influenza Res Treat 2013 15;2013:286158. Epub 2013 Sep 15.

Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent, Central Avenue, Chatham Maritime, Kent ME4 4TB, UK.

The nature of influenza virus to randomly mutate and evolve into new types is an important challenge in the control of influenza infection. It is necessary to monitor virus evolution for a better understanding of the pandemic risk posed by certain variants as evidenced by the highly pathogenic avian influenza (HPAI) viruses. This has been clearly recognized in Egypt following the notification of the first HPAI H5N1 outbreak. Read More

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http://dx.doi.org/10.1155/2013/286158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791816PMC
October 2013
3 Reads

A Time Off Incentive Was Not Associated with Influenza Vaccination Acceptance among Healthcare Workers.

Influenza Res Treat 2013 26;2013:209491. Epub 2013 Jun 26.

University of Tennessee Health Science Center, Memphis, TN 38163, USA.

Objectives. The national influenza vaccination rate among healthcare workers (HCWs) remains low despite clear benefits to patients, coworkers, and families. We sought to evaluate formally the effect of a one-hour time off incentive on attitudes towards influenza vaccination during the 2011-2012 influenza season. Read More

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http://dx.doi.org/10.1155/2013/209491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710596PMC
July 2013
4 Reads

Mortality associated with influenza in tropics, state of são paulo, Brazil, from 2002 to 2011: the pre-pandemic, pandemic, and post-pandemic periods.

Influenza Res Treat 2013 12;2013:696274. Epub 2013 Jun 12.

Epidemiology, Department of Public Health, Faculty of Medical Sciences, State University of Campinas (UNICAMP), 126 Tessália Vieira de Camargo, 13083889 Campinas, SP, Brazil ; São Leopoldo Mandic Medical College, Campinas, SP, Brazil ; Campinas Department of Public Health, Campinas, SP, Brazil.

The impact of the seasonal influenza and 2009 AH1N1 pandemic influenza on mortality is not yet completely understood, particularly in tropical and subtropical countries. The trends of influenza related mortality rate in different age groups and different outcomes on a area in tropical and subtropical climate with more than 41 million people (State of São Paulo, Brazil), were studied from 2002 to 2011 were studied. Serfling-type regression analysis was performed using weekly mortality registries and virological data obtained from sentinel surveillance. Read More

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https://www.hindawi.com/archive/2013/696274/
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http://dx.doi.org/10.1155/2013/696274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694379PMC
July 2013
4 Reads

Point-of-Care Testing as an Influenza Surveillance Tool: Methodology and Lessons Learned from Implementation.

Influenza Res Treat 2013 11;2013:242970. Epub 2013 Apr 11.

Department of Family and Preventive Medicine, University of Utah, 375 Chipeta Way, Suite A, Salt Lake City, UT 84108, USA.

Objectives. Disease surveillance combines data collection and analysis with dissemination of findings to decision makers. The timeliness of these activities affects the ability to implement preventive measures. Read More

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http://dx.doi.org/10.1155/2013/242970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649292PMC
May 2013
21 Reads

Monoclonal Antibody Targeting Neutralizing Epitope on H5N1 Influenza Virus of Clade 1 and 0 for Specific H5 Quantification.

Authors:
Fang He Jimmy Kwang

Influenza Res Treat 2013 5;2013:360675. Epub 2013 Mar 5.

Animal Health Biotechnology, Temasek Life Sciences Laboratory, National University of Singapore, Singapore 117604.

H5N1 influenza viruses cause high mortality in avian and mammalian species, including humans. Antigenic drift in H5 sequence poses challenges in the development of vaccine and therapeutic antibody. In this study, a monoclonal antibody 11G12 was produced from inactivated H5N1 immunized mice. Read More

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http://dx.doi.org/10.1155/2013/360675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603295PMC
March 2013
24 Reads

Comparing Deaths from Influenza H1N1 and Seasonal Influenza A: Main Sociodemographic and Clinical Differences between the Most Prevalent 2009 Viruses.

Influenza Res Treat 2012 30;2012:501784. Epub 2012 Dec 30.

Ministry of Health, 06600 Mexico City, DF, Mexico.

Background. During the 2009 spring epidemic outbreak in Mexico, an important research and policy question faced was related to the differences in clinical profile and population characteristics of those affected by the new H1N1 virus compared with the seasonal virus. Methods and Findings. Read More

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http://dx.doi.org/10.1155/2012/501784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546448PMC
January 2013
4 Reads

Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in Japan.

Influenza Res Treat 2012 25;2012:847505. Epub 2012 Dec 25.

Laboratory of Zoonoses, School of Veterinary Medicine, Kitasato University, Towada 034-8628, Japan ; Animal Health Research Division, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, Bangladesh.

The pandemic influenza virus strains of 1918 (H1N1), 1957 (H2N2), 1968 (H3N2), and 2009 (H1N1) have genes related to avian influenza viruses (AIVs). The nonstructural (NS) gene of AIVs plays a significant role in host-viral interaction. However, little is known about the degree of diversity of this gene in Northern pintail (Anas acuta) ducks wintering in Japan. Read More

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http://dx.doi.org/10.1155/2012/847505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540751PMC
January 2013
4 Reads

Myocarditis Associated with Influenza A H1N1pdm2009.

Influenza Res Treat 2012 17;2012:351979. Epub 2012 Dec 17.

Department of General Internal Medicine, Osaka Medical College, Takatsuki 569-8686, Japan.

Acute myocarditis is a well-known complication of influenza infection. The frequency of myocardial involvement in influenza infection varies widely, with the clinical severity ranging from asymptomatic to fulminant varieties. The worst cases can result in death due to impaired cardiac function, although such fulminant myocarditis associated with influenza infection is rare, as shown by previous papers. Read More

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http://dx.doi.org/10.1155/2012/351979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533457PMC
January 2013
21 Reads

Factors Affecting Medical Students' Uptake of the 2009 Pandemic Influenza A (H1N1) Vaccine.

Influenza Res Treat 2012 28;2012:753164. Epub 2012 Nov 28.

College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

Background. Pandemic influenza vaccination rate amongst healthcare workers in England 2009/2010 was suboptimal (40.3%). Read More

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http://dx.doi.org/10.1155/2012/753164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515892PMC
December 2012
17 Reads

Factors Affecting Acceptance and Intention to Receive Pandemic Influenza A H1N1 Vaccine among Primary School Children: A Cross-Sectional Study in Birmingham, UK.

Influenza Res Treat 2012 17;2012:182565. Epub 2012 Oct 17.

College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

UK pandemic influenza strategy focused on vaccination of high risk groups, although evidence shows that school-age children have the highest infection rates. Vaccination of children might be an additional strategy. We undertook a cross-sectional study amongst 149 parents of primary school children aged 4-7 years in Birmingham, UK to quantify intention to accept pandemic influenza vaccine and identify factors affecting uptake. Read More

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http://dx.doi.org/10.1155/2012/182565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485484PMC
November 2012
6 Reads

Persistence of avian influenza viruses in various artificially frozen environmental water types.

Influenza Res Treat 2012 4;2012:912326. Epub 2012 Oct 4.

Laboratory of Zoonoses, School of Veterinary Medicine, Kitasato University, 35-1 Higashi 23 Bancho, Towada, Aomori 034, Japan.

Background. This study investigates the viable persistence of avian influenza viruses (AIVs) in various types of artificially frozen environmental water and evaluates the feasibility of similar occurrence taking place in nature, and allowing for prolonged abiotic virus survival, with subsequent biotic viral recirculation. Methods. Read More

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http://dx.doi.org/10.1155/2012/912326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471417PMC
October 2012
28 Reads

Clinical and Epidemiologic Characteristics of Hospitalized Patients with 2009 H1N1 Influenza Infection.

Influenza Res Treat 2012 23;2012:603989. Epub 2012 Apr 23.

Department of Clinical Microbiology and Infectious Diseases, Faculty of Medicine, Eskisehir Osmangazi University, 26480 Eskisehir, Turkey.

Objective. 2009 H1N1 virus is a new virus that was firstly detected in April 2009. This virus spreads from human to human and causes a worldwide disease. Read More

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https://www.hindawi.com/archive/2012/603989/
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http://dx.doi.org/10.1155/2012/603989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447285PMC
October 2012
17 Reads

Situation-based survey of avian influenza viruses in possible "bridge" species of wild and domestic birds in Nigeria.

Influenza Res Treat 2012 2;2012:567601. Epub 2012 Sep 2.

Epidemiology Unit, Department of Livestock, Federal Ministry of Agriculture, Area 11, P.M.B 135, Garki, Abuja, Nigeria.

The highly pathogenic avian influenza (H5N1 subtype) recurred in Nigeria after 9 months period of no reported case. A critical look at possible sources of the re-occurrence was desirable. The objective of this study was to determine whether avian influenza viruses were present at reasonably detectable levels (0. Read More

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https://www.hindawi.com/archive/2012/567601/
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http://dx.doi.org/10.1155/2012/567601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447283PMC
October 2012
9 Reads

Influenza-associated mortality in georgia (2009-2011).

Influenza Res Treat 2012 15;2012:480763. Epub 2012 Aug 15.

National Center for Disease Control and Public Health, 9 Asatiani Street 0177 Tbilisi, Georgia.

We analyzed data from NCDCPH Georgia where samples from outpatients with influenza-like illness (ILI) and inpatients with severe acute respiratory syndrome (SARI) are referred for testing on influenza virus using PCR analysis. During 2009-2010 and 2010-2011 influenza pandemics total number of the laboratory-confirmed influenza cases were 1286 with 33 deaths (all of them influenza type A) and 1203 (51.4% type A) with 44 deaths, respectively. Read More

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https://www.hindawi.com/archive/2012/480763/
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http://dx.doi.org/10.1155/2012/480763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447290PMC
October 2012
8 Reads

Pediatric influenza-associated deaths in new york state: death certificate coding and comparison to laboratory-confirmed deaths.

Influenza Res Treat 2012 25;2012:397890. Epub 2012 Sep 25.

Bureau of Communicable Disease Control, New York State Department of Health, Corning Tower Room 651, Albany, Empire State Plaza, NY 12237, USA.

Introduction. Surveillance for laboratory-confirmed influenza-associated deaths in children is used to monitor the severity of influenza at the population level and to inform influenza prevention and control policies. The goal of this study was to better estimate pediatric influenza mortality in New York state (NYS). Read More

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http://dx.doi.org/10.1155/2012/397890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463169PMC
October 2012
2 Reads

Influenza Vaccine Coverage among Pregnant Women in a Public Hospital System during the 2009-2010 Pandemic Influenza Season.

Influenza Res Treat 2012 7;2012:329506. Epub 2012 May 7.

Department of Obstetrics/Gynecology and Women's Health, Maricopa Integrated Health System, Phoenix, AZ 85008, USA ; Department of Research, Maricopa Integrated Health System, Phoenix, AZ 85008, USA ; Department of Obstetrics and Gynecology, District Medical Group, Phoenix, AZ 85016, USA.

The purpose of this study was to compare influenza vaccination rates of pregnant women in a public safety-net health system to national coverage rates during the 2009-2010 pandemic influenza season. A chart review of a random sample of deliveries was undertaken to determine rates of coverage and predictors of vaccine coverage of women who obtained prenatal care and delivered in our health system. Rates were calculated from deliveries from when the vaccine was first available through April 30, 2010. Read More

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http://dx.doi.org/10.1155/2012/329506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447293PMC
October 2012
3 Reads

Comparison of Human-Like H1 (δ-Cluster) Influenza A Viruses in the Swine Host.

Influenza Res Treat 2012 3;2012:329029. Epub 2012 Jun 3.

Virus and Prion Diseases Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, IA 50010, USA ; Labex-USA, Brazilian Agriculture Research Corporation (EMBRAPA), 70770-901 Brasília, DF, Brazil ; Embrapa Swine and Poultry Research Center, 89700-000 Concórdia, SC, Brazil.

Influenza A viruses cause acute respiratory disease in swine. Viruses with H1 hemagglutinin genes from the human seasonal lineage (δ-cluster) have been isolated from North American swine since 2003. The objective of this work was to study the pathogenesis and transmission of δ-cluster H1 influenza viruses in swine, comparing three isolates from different phylogenetic subclusters, geographic locations, and years of isolation. Read More

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http://dx.doi.org/10.1155/2012/329029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447287PMC
October 2012
10 Reads

The modes of evolutionary emergence of primal and late pandemic influenza virus strains from viral reservoir in animals: an interdisciplinary analysis.

Authors:
Dany Shoham

Influenza Res Treat 2011 15;2011:861792. Epub 2011 Nov 15.

The Begin-Sadat Center for Strategic Studies, Bar-Ilan University, Ramat Gan 52900, Israel.

Based on a wealth of recent findings, in conjunction with earliest chronologies pertaining to evolutionary emergences of ancestral RNA viruses, ducks, Influenzavirus A (assumingly within ducks), and hominids, as well as to the initial domestication of mallard duck (Anas platyrhynchos), jungle fowl (Gallus gallus), wild turkey (Meleagris gallopavo), wild boar (Sus scrofa), and wild horse (Equus ferus), presumed genesis modes of primordial pandemic influenza strains have multidisciplinarily been configured. The virological fundamentality of domestication and farming of those various avian and mammalian species has thereby been demonstrated and broadly elucidated, within distinctive coevolutionary paradigms. The mentioned viral genesis modes were then analyzed, compatibly with common denominators and flexibility that mark the geographic profile of the last 18 pandemic strains, which reputedly emerged since 1510, the antigenic profile of the last 10 pandemic strains since 1847, and the genomic profile of the last 5 pandemic strains since 1918, until present. Read More

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http://dx.doi.org/10.1155/2011/861792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447294PMC
October 2012
3 Reads

A Time Course for Susceptibility to Staphylococcus aureus Respiratory Infection during Influenza in a Swine Model.

Influenza Res Treat 2011 11;2011:846910. Epub 2012 Jan 11.

Department of Dairy Science, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.

Bacterial superinfections following influenza A virus (IAV) are predominant causes of morbidity in humans. The recent emergence of methicillin-resistant Staphylococcus aureus (MRSA) and highly virulent IAV strains has reduced treatment options. Development of an appropriate animal model to study secondary S. Read More

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http://dx.doi.org/10.1155/2011/846910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447286PMC
October 2012
10 Reads

Efficacy and Safety of CVT-E002, a Proprietary Extract of Panax quinquefolius in the Prevention of Respiratory Infections in Influenza-Vaccinated Community-Dwelling Adults: A Multicenter, Randomized, Double-Blind, and Placebo-Controlled Trial.

Influenza Res Treat 2011 20;2011:759051. Epub 2011 Jul 20.

UBC Gerontology and Diabetes Research, 186-828 West 10th Avenue, Vancouver, BC, Canada V5Z 1L8.

CVT-E002 (a proprietary extract) was found to be effective in the prevention of upper respiratory infections (URIs) in healthy adults, and institutionalized and community-dwelling seniors. A multicenter, randomized, double-blind, placebo-controlled trial was carried out to determine effects of CVT-E002 in the prevention of URIs in influenza-vaccinated community-dwelling adults. 783 community-dwelling adults were randomized to receive placebo, 400 mg or 800 mg treatment/d (1 : 1 : 1) for 6 months. Read More

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http://dx.doi.org/10.1155/2011/759051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447298PMC
October 2012
2 Reads

Changing patterns of h6 influenza viruses in Hong Kong poultry markets.

Influenza Res Treat 2011 18;2011:702092. Epub 2010 Oct 18.

Laboratory of Veterinary Microbiology, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.

Until 2001, H6N1 influenza viruses in the Hong Kong bird markets were represented by a single stable A/teal/Hong Kong/W312/97-like lineage. Beginning in 2001, despite a reduction in overall prevalence, an increase was observed in the number of H6 viruses isolated from chickens and other hosts. To assess any changes in H6 viruses, we characterized 18 H6 viruses isolated in the Hong Kong bird markets from 2001 to 2003. Read More

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http://www.hindawi.com/journals/irt/2011/702092/
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http://dx.doi.org/10.1155/2011/702092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447289PMC
October 2012
4 Reads

Blow Flies Were One of the Possible Candidates for Transmission of Highly Pathogenic H5N1 Avian Influenza Virus during the 2004 Outbreaks in Japan.

Influenza Res Treat 2011 28;2011:652652. Epub 2010 Dec 28.

Department of Medical Entomology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.

The 2003-2004 H5N1 highly pathogenic avian influenza (HPAI) outbreaks in Japan were the first such outbreaks in 79 years in Japan. Epidemic outbreaks have been occurring in Southeast Asia, with the most recent in 2010. Knowledge of the transmission route responsible for the HPAI outbreaks in these countries remains elusive. Read More

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https://www.hindawi.com/archive/2011/652652/
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http://dx.doi.org/10.1155/2011/652652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447300PMC
October 2012
7 Reads

Predictive and Reactive Distribution of Vaccines and Antivirals during Cross-Regional Pandemic Outbreaks.

Influenza Res Treat 2011 5;2011:579597. Epub 2011 Jun 5.

Department of Industrial and Management Systems Engineering, University of South Florida, Tampa, FL 33620, USA.

As recently pointed out by the Institute of Medicine, the existing pandemic mitigation models lack the dynamic decision support capability. We develop a large-scale simulation-driven optimization model for generating dynamic predictive distribution of vaccines and antivirals over a network of regional pandemic outbreaks. The model incorporates measures of morbidity, mortality, and social distancing, translated into the cost of lost productivity and medical expenses. Read More

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http://dx.doi.org/10.1155/2011/579597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447295PMC
October 2012
2 Reads

Pathological Findings and Distribution of Pandemic Influenza A (H1N1) 2009 Virus in Lungs from Naturally Infected Fattening Pigs in Norway.

Influenza Res Treat 2011 20;2011:565787. Epub 2011 Dec 20.

Department of Laboratory Services, Norwegian Veterinary Institute, Pb 750 Sentrum, N-0106 Oslo, Norway.

The Norwegian pig population was considered free from influenza A virus infections until the first case of porcine pandemic influenza A (H1N1) 2009 virus infection in October 2009. Human to pig transmission of virus was suspected. Unusual lung lesions were observed in fattening pigs, with red, lobular, multifocal to coalescing consolidation, most frequently in the cranial, middle, and accessory lobes. Read More

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http://dx.doi.org/10.1155/2011/565787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447288PMC
October 2012
2 Reads

Influenza vaccination in the face of immune exhaustion: is herd immunity effective for protecting the elderly?

Influenza Res Treat 2011 29;2011:419216. Epub 2012 Jan 29.

Department of Internal Medicine, Rehabilitation and Geriatrics, Medical school and University Hospitals of Geneva, CH-1226 Thônex-Geneva, Switzerland ; Translational Medicine Research Group, Cranfield Health, Cranfield University, Cranfield MK43 0AL, UK.

At the start of the 21st century, seasonal influenza virus infection is still a major public health concern across the world. The recent body of evidence confirms that trivalent inactivated influenza vaccines (TIVs) are not optimal within the population who account for approximately 90% of all influenza-related death: elderly and chronically ill individuals regardless of age. With the ever increasing aging of the world population and the recent fears of any pandemic influenza rife, great efforts and resources have been dedicated to developing more immunogenic vaccines and strategies for enhancing protection in these higher-risk groups. Read More

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http://dx.doi.org/10.1155/2011/419216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447292PMC
October 2012
5 Reads
2 Citations

Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys.

Influenza Res Treat 2011 30;2011:285218. Epub 2010 Dec 30.

Division of Avian Diseases, Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel.

An avian influenza virus (AIV), A/turkey/Israel/09 subtype H6N1, was isolated from turkey poults exhibiting typical pathology associated with AIV infection. The virus was characterized by RT-PCR using AIV subtype-specific primers and by the haemagglutination inhibition test using AIV subtype-specific antisera. The virus has an intravenous pathogenicity index of 0 and possessed a nucleotide sequence at the cleavage site of the hemagglutinin gene, PQIETR*GLF, associated with avian influenza viruses of low pathogenicity. Read More

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http://dx.doi.org/10.1155/2011/285218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447296PMC
October 2012
2 Reads

Experiences after Twenty Months with Pandemic Influenza A (H1N1) 2009 Infection in the Naïve Norwegian Pig Population.

Influenza Res Treat 2011 3;2011:206975. Epub 2012 Jan 3.

Department of Laboratory Services, Norwegian Veterinary Institute, P.O. Box 750 Sentrum, 0106 Oslo, Norway.

Pandemic (H1N1) 2009 influenza A virus was detected in Norwegian pigs in October 2009. Until then, Norway was regarded free of swine influenza. Intensified screening revealed 91 positive herds within three months. Read More

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http://dx.doi.org/10.1155/2011/206975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447302PMC
October 2012
3 Reads

Clinical Impact of Infection with Pandemic Influenza (H1N1) 2009 Virus in Naïve Nucleus and Multiplier Pig Herds in Norway.

Influenza Res Treat 2011 22;2011:163745. Epub 2011 Dec 22.

Norwegian School of Veterinary Science, Department of Production Animal Clinical Sciences, P.O. Box 8146, 0033 Oslo, Norway.

The Norwegian pig population has been free from influenza viruses until 2009. The pandemic influenza outbreak during the autumn 2009 provided an opportunity to study the clinical impact of this infection in an entirely naïve pig population. This paper describes the results of a case-control study on the clinical impact of pandemic influenza (H1N1) 2009 infection in the nucleus and multiplier herds in Norway. Read More

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http://dx.doi.org/10.1155/2011/163745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447284PMC
October 2012
2 Reads

A Novel Vaccine Using Nanoparticle Platform to Present Immunogenic M2e against Avian Influenza Infection.

Influenza Res Treat 2011 12;2011:126794. Epub 2012 Jan 12.

Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, Storrs, CT 06268, USA.

Using peptide nanoparticle technology, we have designed two novel vaccine constructs representing M2e in monomeric (Mono-M2e) and tetrameric (Tetra-M2e) forms. Groups of specific pathogen free (SPF) chickens were immunized intramuscularly with Mono-M2e or Tetra-M2e with and without an adjuvant. Two weeks after the second boost, chickens were challenged with 107. Read More

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http://dx.doi.org/10.1155/2011/126794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447297PMC
October 2012
9 Reads

Shedding of the Pandemic Swine-Origin Influenza A Virus (H1N1) after Oseltamivir Administration.

Influenza Res Treat 2010 14;2010:976084. Epub 2010 Dec 14.

Unit of Viral Genome Regulation, Institut Pasteur of Shanghai, The Key Laboratory of Virology and Immunology, Chinese Academy of Sciences, 411 Hefei Road, Shanghai 200025, China.

We analyzed the virus shedding of an oseltamivir-treated patient who had been infected with the pandemic swine-origin influenza A (H1N1) virus which had an oseltamivir-sensitive neuraminidase. The virus was isolated from the pharyngeal swabs of the patient using MDCK cells, and the virus genome RNA was detected in the same samples both by real-time RT-PCR and RT-PCR. The virus was isolated until 44 h after oseltamivir administration although the virus genome was detected until one day after oseltamivir treatment was stopped. Read More

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http://dx.doi.org/10.1155/2010/976084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447301PMC
October 2012
3 Reads

Factors associated with increased risk perception of pandemic influenza in australia.

Influenza Res Treat 2010 20;2010:947906. Epub 2010 Jul 20.

School of Medicine, University of Western Sydney, Penrith South DC, NSW 1797, Australia.

The aim of this study was to assess factors associated with increased risk perception of pandemic influenza in Australia. The sample consisted of 2081 Australian adults aged 16 years and older who completed a short three item pandemic influenza question module which was incorporated into the NSW Health Adult Population Health Survey during the first quarter of 2007. After adjusting for covariates, multivariate analysis indicated that those living in rural regions were significantly more likely to perceive a high risk that a pandemic influenza would occur, while those with poor self-rated health perceived both a high likelihood of pandemic and high concern that self/family would be directly affected were such an event to occur. Read More

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http://dx.doi.org/10.1155/2010/947906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447299PMC
October 2012
5 Reads

Ten-year (1999-2009) epidemiological and virological surveillance of influenza in South Italy (Apulia).

Influenza Res Treat 2010 22;2010:642492. Epub 2010 Jun 22.

Laboratory of Hygiene, Department of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, Via Prov. Le Lecce-Monteroni 73100 Lecce, Italy.

Clinical and epidemiological surveillance of influenza and other Acute Respiratory Infections (ARI) are currently a major objective of Public Health. The aim was to describe the epidemiology of influenza using the Italian surveillance system. Vaccination Coverage (VC) rates were calculated during 1999-2009 influenza seasons. Read More

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http://dx.doi.org/10.1155/2010/642492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447291PMC
October 2012
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Evaluation of a Subunit H5 Vaccine and an Inactivated H5N2 Avian Influenza Marker Vaccine in Ducks Challenged with Vietnamese H5N1 Highly Pathogenic Avian Influenza Virus.

Influenza Res Treat 2010 27;2010:489213. Epub 2010 Jun 27.

School of Veterinary and Biomedical Sciences, Murdoch University, 90 South Street Murdoch, WA 6150, Australia ; Agri-Food and Veterinary Authority of Singapore, 5 Maxwell Road, Singapore 069110.

The protective efficacy of a subunit avian influenza virus H5 vaccine based on recombinant baculovirus expressed H5 haemagglutinin antigen and an inactivated H5N2 avian influenza vaccine combined with a marker antigen (tetanus toxoid) was compared with commercially available inactivated H5N2 avian influenza vaccine in young ducks. Antibody responses, morbidity, mortality, and virus shedding were evaluated after challenge with a Vietnamese clade 1 H5N1 HPAI virus [A/VN/1203/04 (H5N1)] that was known to cause a high mortality rate in ducks. All three vaccines, administered with water-in-oil adjuvant, provided significant protection and dramatically reduced the duration and titer of virus shedding in the vaccinated challenged ducks compared with unvaccinated controls. Read More

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http://dx.doi.org/10.1155/2010/489213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447282PMC
October 2012
9 Reads
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