37,096 results match your criteria Infective Endocarditis

Intracranial complications of acute bacterial endocarditis.

Surg Neurol Int 2018 25;9:107. Epub 2018 May 25.

Infectious Disease Division, Winthrop-University Hospital, Mineola, New York, USA.

Background: Infectious endocarditis (IE) clinically manifests as either subacute bacterial endocarditis (SBE) or acute bacterial endocarditis (ABE). Neurologic manifestations are markedly different for these two entities. ABE is caused by invasive, highly virulent pathogens (e. Read More

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Risk Stratification and Optimization of Cardiac Surgical Patients With Infective Endocarditis: Does It Matter?

J Cardiothorac Vasc Anesth 2018 Feb 6. Epub 2018 Feb 6.

Department of Anesthesiology, The Ohio State University, Columbus, Ohio.

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February 2018

[Infective endocarditis:an emergency well too minimized].

Rev Med Liege 2018 May;73(5-6):283-289

Service de Cardiologie, CHU Sart Tilman, Liège, Belgique.

Infective endocarditis is a rare disease that can lead to some diagnostic wandering because of its often nonspecific and polymorphic clinical manifestations. This latency is at the origin of severe cardiac and extra-cardiac complications, yet highly fatal. The clinician should always bear in mind the differential diagnosis of a patient with fever of undetermined origin, with risk factors for valve infection such as foreign material, and history recent invasive procedures (including dental procedures) or recent hospitalization. Read More

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Mitral valve repair or replacement in native valve endocarditis? Systematic review and meta-analysis.

J Card Surg 2018 Jun 21. Epub 2018 Jun 21.

Department of Cardiac Surgery, Barts Heart Centre, St. Bartholomew's Hospital, London, UK.

Objective: The objective of this study is to review the morbidity and mortality associated with mitral valve repair versus replacement in infective endocarditis patients.

Methods: A comprehensive search was undertaken among the four major databases (PubMed, Embase, Scopus, and Ovid) to identify all available data comparing mitral valve repair or replacement in infective endocarditis. Databases were evaluated and assessed to March 2017. Read More

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A challenging case of carbapenemase-producing Klebsiella pneumoniae septic thrombophlebitis and right mural endocarditis successfully treated with ceftazidime/avibactam.

Infection 2018 Jun 20. Epub 2018 Jun 20.

Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, Rome, Italy.

Introduction: The emergence of carbapenemase-producing Klebsiella pneumonia (KPC-Kp) has become a significant problem in terms of public health and clinical outcome in many hospitals in Southern Europe. Treatment options are usually limited and effective treatment of infections caused by these pathogens is a considerable challenge for clinicians. Ceftazidime-avibactam has been recently approved for the treatment of difficult-to-treat infections due to aerobic Gram-negative organisms in patients with limited treatment options. Read More

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The ratio of concentrations of aminocaproic acid and tranexamic acid that prevent plasmin activation of platelets does not provide equivalent inhibition of plasmatic fibrinolysis.

J Thromb Thrombolysis 2018 Jun 20. Epub 2018 Jun 20.

Department of Anesthesiology, The University of Arizona College of Medicine, P.O. Box 245114, 1501 North Campbell Avenue, Tucson, AZ, 85724-5114, USA.

Aminocaproic acid (EACA) availability has recently been decreased whereas tranexamic acid (TXA) is still available as an antifibrinolytic agent to decrease blood loss associated with procedures involving cardiopulmonary bypass (CPB) by inhibiting plasmin mediated platelet activation. Given that the clinical inclination is to substitute TXA for EACA, we sought to compare the antifibrinolytic efficacy of the two agents using the clinically accepted molar ratio of EACA:TXA (7.9:1) that prevents platelet activation in a viscoelastic based system under a variety of conditions in human plasma; 25-50% therapeutic concentration (EACA 32. Read More

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Changes in the Association of Rising Infective Endocarditis With Mortality in People Who Inject Drugs.

JAMA Cardiol 2018 Jun 20. Epub 2018 Jun 20.

Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio.

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Case of infective endocarditis caused by implanted artificial hair pyoderma.

J Dermatol 2018 Jun 20. Epub 2018 Jun 20.

Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan.

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Guidelines in review: Comparison of ESC and AHA guidance for the diagnosis and management of infective endocarditis in adults.

J Nucl Cardiol 2018 Jun 19. Epub 2018 Jun 19.

King's College London and Guy's and St Thomas' NHS Foundation Trust PET Centre, London, UK.

Over recent years, new evidence has led a rethinking of the available guidance on the diagnosis and management of infective endocarditis (IE). This review compares the most recently available guidance provided by the American Heart Association (AHA) IE Writing Committee, and the Task Force for the management of IE of the European Society of Cardiology (ESC). This represents the sixth of a new series of comparative guidelines review published in the Journal. Read More

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Infective Endocarditis Associated with Atrial Septal Defect in an Intravenous Drug Abuser: A Case Report.

Cureus 2018 Apr 15;10(4):e2482. Epub 2018 Apr 15.

Dow Medical College, Dow University of Health Sciences (DUHS), Karachi, PAK.

Atrial septal defect (ASD) is a common congenital abnormality, which accounts for 20-40% of all the adult patients with congenital heart diseases. Due to the slow velocity of shunt flow, ASD has a negligible risk for infective endocarditis (IE). However, intravenous drug abuse (IVDA) is a potential cause for IE. Read More

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Population-based treated prevalence, risk factors, and outcomes of bicuspid aortic valve in a pediatric Medicaid cohort.

Ann Pediatr Cardiol 2018 May-Aug;11(2):119-124

Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine, Columbia, SC, USA.

Background: We investigated the treated prevalence of bicuspid aortic valve in a pediatric population with congenital heart disease and its incident complications.

Materials And Methods: A 15-year retrospective data set was analyzed. Selection criteria included age ≤17 years, enrollees in the South Carolina State Medicaid program and diagnosed as having bicuspid aortic valve on one or more service visits. Read More

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June 2018
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Validation of discharge diagnosis codes to identify serious infections among middle age and older adults.

BMJ Open 2018 Jun 19;8(6):e020857. Epub 2018 Jun 19.

Department of Health Policy, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Objectives: Hospitalisations for serious infections are common among middle age and older adults and frequently used as study outcomes. Yet, few studies have evaluated the performance of diagnosis codes to identify serious infections in this population. We sought to determine the positive predictive value (PPV) of diagnosis codes for identifying hospitalisations due to serious infections among middle age and older adults. Read More

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Mitral valve repair for patients with infectious endocarditis-Is it the procedure of choice for all patients?

Harold L Lazar

J Card Surg 2018 Jun 19. Epub 2018 Jun 19.

Division of Cardiac Surgery, the Boston University School of Medicine, Boston, Massachusetts.

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Long-term risk of hemorrhagic stroke in patients with infective endocarditis: a Danish nationwide cohort study.

Clin Infect Dis 2018 Jun 16. Epub 2018 Jun 16.

Department of Cardiology, Herlev Gentofte hospital, Herlev Ringvej, Herlev, Copenhagen, Denmark.

Background: The present study aimed to investigate the long-term risk of hemorrhagic stroke (HS) in patients with infective endocarditis (IE).

Methods: Using a register-based nationwide cohort of 9 million Danes, we propensity score-matched patients with left-sided IE from 1977 to mid-2015 with IE-free individuals (1:10). Follow up started one year after the IE diagnosis. Read More

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Infective endocarditis in Western Norway: a 20-year retrospective survey.

Infect Dis (Lond) 2018 Jun 19:1-7. Epub 2018 Jun 19.

a Section of Infectious Disease, Department of Medicine , Haukeland University Hospital , Bergen , Norway.

Background: To investigate epidemiological trends of infective endocarditis (IE) in western Norway a retrospective study was performed.

Methods: Characteristics of 706 IE admissions from 1996 to 2005 and 2006 to 2015 were analysed and compared using the Chi-square test for categorical variables and the t-test for age. Survival was analysed by multiple Cox regression and reported by the hazard ratio (HR). Read More

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Daptomycin associated eosinophilic pneumonia: case report and differential diagnoses.

J Community Hosp Intern Med Perspect 2018 12;8(3):152-155. Epub 2018 Jun 12.

Maharajgunj Medical Campus, Tribhuvan University, Kathmandu, Nepal.

Daptomycin is a bactericidal antibiotic approved for treatment of gram-positive skin and soft tissue infections. We present a case of an 89-year-old man who presented with fever, shortness of breath and nonproductive cough on week 4 of starting daptomycin for infective endocarditis. Computerized tomography scan showed bilateral interstitial infiltrates predominantly affecting the lower lobes. Read More

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Infective Endocarditis and Colorectal Carcinoma: Case of New Association Gaining Ground.

Gastroenterology Res 2018 Jun 31;11(3):238-240. Epub 2018 May 31.

Department of Hematology and Oncology, Tufts Medical Center, Boston, MA, USA.

Mostly () bacteremia and endocarditis (60%) has been found to be associated with underlying colorectal cancer (CRC). () bacteremia and endocarditis has no identifiable source in most of the cases. is part of normal gut flora that can translocate through the intestine and cause the systemic infection. Read More

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Dipeptidylpeptidase IV of Streptococcus suis degrades the porcine antimicrobial peptide PR-39 and neutralizes its biological properties.

Microb Pathog 2018 Jun 15. Epub 2018 Jun 15.

Groupe de Recherche en Écologie Buccale (GREB), Faculté de Médecine Dentaire, Université Laval, Quebec City, Quebec, Canada; Centre de Recherche en Infectiologie Porcine et Avicole (CRIPA), Fonds de Recherche du Québec - Nature et Technologies (FRQNT), Saint-Hyacinthe, Quebec, Canada. Electronic address:

Streptococcus suis is a major swine pathogen causing pathologies such as meningitis, sepsis, endocarditis, and arthritis. Several surface-bound and secreted proteases produced by S. suis have been identified and proposed as virulence factors. Read More

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Homograft Versus Conventional Prosthesis for Surgical Management of Aortic Valve Infective Endocarditis: A Systematic Review and Meta-analysis.

Innovations (Phila) 2018 May/Jun;13(3):163-170

From the Division of Cardiac Surgery.

Objective: Surgical management of aortic valve infective endocarditis (IE) with cryopreserved homograft has been associated with lower risk of recurrent IE, but there is equipoise with regard to the optimal prosthesis. This systematic review and meta-analysis were performed to compare outcomes between homograft and conventional prosthesis for aortic valve IE.

Methods: We searched MEDLINE database to September 2017 for studies comparing homograft versus conventional prosthesis. Read More

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Hybrid 18F-fluorodeoxyglucose positron emission tomography/CT angiography in percutaneous pulmonary prosthetic valve endocarditis.

Eur Heart J Cardiovasc Imaging 2018 Jun 14. Epub 2018 Jun 14.

Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Dr. Molenwaterplein 40, 3015 GD, Rotterdam, The Netherlands.

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Congenital Aorto-Right Ventricular Fistula Associated with Pulmonary Hypertension in an Old Female Patient.

J Cardiovasc Echogr 2018 Apr-Jun;28(2):141-142

Department of Cardiology, Santa Maria Hospital GVM Care and Research, Bari, Italy.

We report a late clinical presentation of an aorto-right ventricular fistula (RVF) extending from the right sinus of Valsalva into the RV outflow tract with significant left-to-right shunt and severe pulmonary hypertension. A three-dimensional transesophageal echocardiogram and a chest-computed tomography scans were performed to better characterize the abnormality. Aorto- RVF can be either congenital or acquired, secondary to endocarditis, Valsalva aneurysm rupture, chest trauma, or aortic dissection. Read More

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Rupture of Sinus of Valsalva Aneurysm into Left Atrium in a Patient who is a Candidate for Hepatic Transplantation.

J Cardiovasc Echogr 2018 Apr-Jun;28(2):130-132

Department of Cardiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.

Sinus of valsalva aneurysm (SVA) is a rare cardiac disease. The most common complication of SVA is rupture into the right atrium or right ventricle. Rupture into the left chambers is very rare. Read More

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Three-dimensional Transesophageal Echocardiographic Diagnosis of Catheter Endocarditis Hidden in Intracaval Stent.

J Cardiovasc Echogr 2018 Apr-Jun;28(2):124-126

Department of Hospital, Cardiology Unit, Hospital Policlinico, Bari, Italy.

In recent years, with an increasing number of central venous access procedures and cardiac implantable electronic device implantation, the incidence of infective endocarditis (IE) has become more prevalent. Two-dimensional transthoracic echocardiography (2D-TTE) and transesophageal echocardiography (TEE) are a key part of the evaluation of IE, but advances in three-dimensional echocardiography have enabled a better spatial resolution and visualization of cardiac structures, allowing the identification of any valvular vegetations, abscesses, or nodules. Herein, we report the usefulness of 3D-TEE in a difficult diagnosis of hemodialysis catheter endocarditis hidden in intracaval stent. Read More

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Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design.

J Cardiovasc Echogr 2018 Apr-Jun;28(2):78-89

Cardiology Department, Ca' Foncello Hospital, Treviso, Italy.

Background: Bicuspid aortic valve (BAV) is the most common congenital heart disease, affecting 0.5%-2% of the general population. It is associated not only with notable valvular risk (aortic stenosis and/or regurgitation, endocarditis) but also with aortopathy with a wide spectrum of unpredictable clinical presentations, including aneurysmal dilation of the aortic root and/or ascending thoracic aorta, isthmic coarctation, aortic dissection, or wall rupture. Read More

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Assessment of the Dual Role of Clumping Factor A in S. Aureus Adhesion to Endothelium in Absence and Presence of Plasma.

Thromb Haemost 2018 Jun 17. Epub 2018 Jun 17.

Division of Cardiovascular Developmental Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.

Adhesion of to endothelial cells (ECs) is paramount in infective endocarditis. Bacterial proteins such as clumping factor A (ClfA) and fibronectin binding protein A (FnbpA) mediate adhesion to EC surface molecules and (sub)endothelial matrix proteins including fibrinogen (Fg), fibrin, fibronectin (Fn) and von Willebrand factor (vWF). We studied the influence of shear flow and plasma on the binding of ClfA and FnbpA (including its sub-domains A, A, ABC, CD) to coverslip-coated vWF, Fg/fibrin, Fn or confluent ECs, making use of , expressing these adhesins heterologously. Read More

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Autoimmunity and B-cell dyscrasia in acute and chronic Q fever: A review of the literature.

Eur J Intern Med 2018 Jun 13. Epub 2018 Jun 13.

Department of Internal Medicine, Division of Infectious Diseases, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands; Radboud Expert Center for Q fever, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. Electronic address:

Q fever infection can lead to chronic Q fever, a potentially lethal disease occurring in 1-5% of patients infected with Coxiella burnetii, characterized by the persistence of this intracellular bacterium. It usually presents as endocarditis, infected vascular aneurysms, or infected vascular prostheses. This systematic review of the literature discusses the various autoimmune syndromes and B-cell dyscrasias in acute and chronic Q fever patients, that may interfere with or impede recognition and diagnosis of Q fever. Read More

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Valvectomy versus Replacement for the Surgical Treatment of Tricuspid Endocarditis (Commentary).

Ann Thorac Surg 2018 Jun 13. Epub 2018 Jun 13.

Division of Cardiac Surgery, University of Ottawa Heart Institute, 40Ruskin Street, Ottawa, ON, Canada, K1Y 4W7. Electronic address:

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Prediabetes and diabetes are both risk factors for adverse outcomes in infective endocarditis.

Diabet Med 2018 Jun 16. Epub 2018 Jun 16.

Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangzhou.

Aim: Diabetes is a risk factor in infective endocarditis. However, few studies have focused on the prognostic value of prediabetes in infective endocarditis. This analysis aimed to explore the relationship between prediabetes and outcomes for people with infective endocarditis. Read More

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Diagnostic yield of F-FDG PET/CT in suspected diagnosis of vascular graft infection: A prospective cohort study.

J Nucl Cardiol 2018 Jun 15. Epub 2018 Jun 15.

Infectious Diseases Service, Hospital Clinic, Barcelona, Spain.

Background: Prosthetic vascular graft infection (PVGI) is a severe complication associated with high morbidity and mortality. Clinical diagnosis is complex, requiring image testing such as CT angiography or leukocyte scintigraphy, which has considerable limitations. The aim of this study was to know the diagnostic yield of PET/CT with F-Fluorodeoxyglucose (F-FDG) in patients with suspected PVGI. Read More

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June 2018
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Achromobacter endocarditis in native cardiac valves - an autopsy case report and review of the literature.

Cardiovasc Pathol 2018 May 22;36:6-10. Epub 2018 May 22.

Department of Pathology, State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA. Electronic address:

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infective endocarditis of native valves in an immunocompetent host.

IDCases 2018 15;12:66-70. Epub 2018 Mar 15.

OSF Saint Francis Medical Center, Peoria, IL, USA.

With the emergence of Human immunodeficiency virus (HIV) and the resulting immunocompromised state, infections have gained more importance in clinical practice. Cryptococcal infections in immunocompetent hosts continue to be uncommon. We present a rare case of infective endocarditis (IE) in a young immunocompetent male. Read More

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Advanced imaging improves the diagnosis of infective endocarditis.

F1000Res 2018 29;7. Epub 2018 May 29.

Department of Cardiology, St Thomas' Hospital, London, UK.

Infective endocarditis is a heterogeneous condition whose incidence is rising. Despite advances in surgery and diagnostic methods, one-year mortality has not changed and it remains at 30%. Patients with prosthetic valve and intra-cardiac device-related endocarditis are being seen more frequently and this condition is difficult to diagnose with conventional microbiological and imaging techniques. Read More

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A Rare Case of Native Mitral Valve Endocarditis Culminating Into a Cerebrovascular Infarction.

Cardiol Res 2018 Jun 6;9(3):173-175. Epub 2018 Jun 6.

Department of Cardiology, Morristown Medical Center, Morristown, NJ 07960, USA.

We report a case of a 56-year-old man who presented initially with a sudden onset of right-sided facial droop and weakness, aphasia, and confusion with no associated fever, chills, syncope, fatigue, weight loss, night sweats, nausea, vomiting, diarrhea, odontalgia, palpitations, cough, or dyspnea. Code stroke was called and the patient received tissue plasminogen activator (tPA) with subsequent resolution of his symptoms. Cranial magnetic resonance imaging showed left frontal punctate cortical restricted diffusion consistent with subacute to acute infarction. Read More

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June 2018
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Periodontal Disease, Systemic Inflammation and the Risk of Cardiovascular Disease.

Heart Lung Circ 2018 Jun 2. Epub 2018 Jun 2.

Internal Medicine Department, Hospital Universitario, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México; Echocardiography Laboratory, Cardiology Service, Hospital Universitario, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.

Periodontal and cardiovascular disease are both major health issues. Poor oral health has long been associated with the development of systemic diseases, with the typical example being the risk of endocarditis posterior to dental procedures. Through the years, the association of periodontal disease with other non-infectious systemic diseases has been brought to attention. Read More

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[Non-infective endocarditis].

Rev Med Interne 2018 Jun 11. Epub 2018 Jun 11.

Service des maladies infectieuses et de réanimation médicale, CHU Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex, France. Electronic address:

Non-infective endocarditis, also referred to as non-bacterial thrombotic endocarditis, represent a wide range of rare pathologies, often severe. This review gathered the data available in the literature, to decipher the major information collected on the pathophysiology, the diagnosis and the treatment of these heterogeneous diseases, often misdiagnosed. Characteristics of non-infective endocarditis are similar to infective endocarditis in terms of valvular lesions (mostly left-sided, with regurgitations and vegetations), and their complications (embolism). Read More

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Infective Endocarditis After Invasive Medical and Surgical Procedures.

J Am Coll Cardiol 2018 Jun;71(24):2753-2755

Oxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

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Invasive Procedures Associated With the Development of Infective Endocarditis.

J Am Coll Cardiol 2018 Jun;71(24):2744-2752

Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.

Background: Various invasive medical procedures might induce bacteremia and, hence, act as triggers for infective endocarditis. However, empirical data in humans on the potential dangers of invasive medical procedures in this regard are very sparse. Due to lack of sufficient data, it is currently debated whether the risk for endocarditis with medical procedures is substantial or rather negligible. Read More

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June 2018
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Antibiotic Prophylaxis Against Infective Endocarditis: Widening the Net?

John B Chambers

J Am Coll Cardiol 2018 Jun;71(24):2741-2743

Cardiothoracic Centre, Guy's and St. Thomas' Hospitals, London, United Kingdom. Electronic address:

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Infective Endocarditis in Patients With Bicuspid Aortic Valve or Mitral Valve Prolapse.

J Am Coll Cardiol 2018 Jun;71(24):2731-2740

Department of Cardiology, Hospital Universitario Puerta de Hierro, CIBERCV, Madrid, Spain; University Francisco de Vitoria, Pozuelo de Alarcon, Madrid, Spain. Electronic address:

Background: There is little information concerning infective endocarditis (IE) in patients with bicuspid aortic valve (BAV) or mitral valve prolapse (MVP). Currently, IE antibiotic prophylaxis (IEAP) is not recommended for these conditions.

Objectives: This study sought to describe the clinical and microbiological features of IE in patients with BAV and MVP and compare them with those of IE patients with and without IEAP indication, to determine the potential benefit of IEAP in these conditions. Read More

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On-X mitral valve replacement: a single-centre experience in 318 patients.

Interact Cardiovasc Thorac Surg 2018 Jun 12. Epub 2018 Jun 12.

Department of Cardiothoracic Surgery, S. Orsola Hospital, University of Bologna, Bologna, Italy.

Objectives: If mitral valve repair is not feasible, mitral valve replacement remains the only option. Based on our overall experience with the On-X mitral valve, the aim of this study was to investigate early and late outcomes after mitral valve replacement using this latest generation prosthesis.

Methods: From 1998 to 2016, 600 patients received an On-X prosthesis in the mitral position. Read More

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Clinical analysis of 215 consecutive cases with fever of unknown origin: A cohort study.

Medicine (Baltimore) 2018 Jun;97(24):e10986

Department of Emergency, PLA General Hospital, Beijing, China.

Fever of unknown origin (FUO) is a frequently observed phenomenon in clinical practice. The present study was aimed to investigate potential causes of FUO, thereby improving clinical diagnosis of this disorder.In this retrospective study, clinical data were collected from 215 patients who were diagnosed with FUO between January 2009 and December 2010, and an 18 to 36 months follow-up visit was also performed for these patients. Read More

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Data set characterizing the systemic alterations of microvascular reactivity and capillary density, in patients presenting with infective endocarditis.

Data Brief 2018 Jun 15;18:480-491. Epub 2018 Mar 15.

National Institute of Cardiology, Ministry of Health, Rio de Janeiro, Brazil.

This article represents data associated with a prior publication from our research group, under the title: Evaluation of microvascular endothelial function and capillary density in patients with infective endocarditis using laser speckle contrast imaging and video-capillaroscopy [1]. Patients with definite infective endocarditis, under stable clinical conditions, were prospectively included. The clinical and laboratory features are presented for each of them in raw form. Read More

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Staphylococcus Lugdunensis Endocarditis and Cerebrovascular Accident: A Systemic Review of Risk Factors and Clinical outcome.

Cureus 2018 Apr 12;10(4):e2469. Epub 2018 Apr 12.

Division of Cardiology, Brooklyn Hospital Center/Mount Sinai Hospital, New York, USA.

Infective endocarditis (IE) secondary to Staphylococcus lugdunensis has been increasingly recognized since 1988. IE-related thromboembolism represents an associated complication of the disease and carries a dismal prognosis. However, the incidence of cerebrovascular accident secondary to S. Read More

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FISH and PNA FISH for the diagnosis of Q fever endocarditis and vascular infections.

J Clin Microbiol 2018 Jun 13. Epub 2018 Jun 13.

Aix Marseille Université, IRD, AP-HM, MEPHI, IHU-Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005 Marseille, France

Endocarditis and vascular infections are common manifestations of persistent localized infection due to and recently, fluorescence in situ hybridization (FISH) was proposed as an alternative tool for their diagnosis. In this study, we evaluated the efficiency of FISH in a series of valve and vascular samples infected by We tested 23 -positive valves and thrombus samples obtained from patients with Q fever endocarditis. Seven aneurysms and thrombus specimens were retrieved from patients with Q fever vascular infection. Read More

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June 2018
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Oral Health Status, Health Behaviour and Treatment Needs of Patients Undergoing Cardiovascular Surgery.

Braz J Cardiovasc Surg 2018 Mar-Apr;33(2):151-154

Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India.

Objective: The aim of the present study was to assess the oral health status and treatment needs of cardiovascular surgery patients. Second, the awareness of cardiovascular surgery patients regarding the association between oral health and heart disease was considered.

Methods: Assessment of oral health status, oral hygiene practices and treatment needs of 106 hospitalized patients in preparation for cardiovascular surgery. Read More

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prosthetic valve endocarditis presenting as a stroke.

JMM Case Rep 2018 May 6;5(5):e005147. Epub 2018 Apr 6.

Microbiology Department, Queen Alexandra Hospital, Southwick Hill Rd, Cosham, Portsmouth PO6 3LY, UK.

Introduction: is a common pathogen of the gastrointestinal tract, but invasive disease is rare. can play a role in osteomyelitis, meningitis and joint infection and has a prediliction for the vascular endothelium, causing mycotic aneurysms, thrombophlebitis and endocarditis. Here we present a case of prosthetic valve endocarditis caused by and a review of the literature. Read More

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Conjugating Existing Clinical Drugs With Gold Nanoparticles for Better Treatment of Heart Diseases.

Front Physiol 2018 29;9:642. Epub 2018 May 29.

School of Chemistry and Biosciences, University of Bradford, Bradford, United Kingdom.

Developing new methods to treat heart diseases is always a focus for basic research and clinical applications. Existing drugs have strong side-effects and also require lifetime administration for patients. Recent attempts of using nanoparticles (NPs) in treating atherosclerosis in animals and some heart diseases such as heart failure and endocarditis have provided hopes for better drug delivery and reducing of drug side-effects. Read More

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Non-vitamin K antagonist oral anticoagulants and infective endocarditis.

Heart 2018 Jul;104(13):1135-1136

Laboratório de Farmacologia Clínica e Terapêutica, Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-028, Lisboa, Portugal.

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Sub-acute leaflet thrombosis: a reversible cause of aortic stenosis.

Echo Res Pract 2018 Jun 12. Epub 2018 Jun 12.

Chasapi A, Wessex Cardiac and Cardiothoracic Unit, University Hospital Southampton, Southampton, UK.

A 77 year old male underwent elective bioprosthetic aortic valve replacement (23mm Carpentier-Edwards Perimount MagnaEase) for severe aortic stenosis. His pre-discharge transthoracic echocardiogram (TTE) was normal. He presented 9 days after surgery with dyspnoea and fever. Read More

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June 2018
2 Reads

Marantic endocarditis: incidental infarcts leading to diagnosis of pancreatic cancer.

BMJ Case Rep 2018 Jun 12;2018. Epub 2018 Jun 12.

Internal Medicine, Banner University Medical Center Tucson, Tucson, Arizona, USA.

Non-bacterial thrombotic endocarditis (NBTE) is a well-described phenomenon associated with malignancies due to hypercoaguable state. In the setting of pancreatic cancer, NBTE is more commonly diagnosed postmortem. We describe a case of a man who was diagnosed with pancreatic carcinoma after incidental finding of NBTE. Read More

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June 2018
1 Read