8,301 results match your criteria Infectious Endocarditis


Native aortic versus mitral valve infective endocarditis: a nationwide registry study.

Open Heart 2019 27;6(1):e000926. Epub 2019 Feb 27.

Division of Cardiothoracic Surgery, Department for Clinical Sciences Lund, Skane University Hospital and Lund University, Lund, Sweden.

Background: Native aortic and mitral valve infective endocarditis (AVE and MVE, respectively) are usually grouped together as left-sided native valve infective endocarditis (LNVE), while the differences between AVE and MVE have not yet been properly investigated. We aimed to compare AVE and MVE in regard to patient characteristics, microbiology and determinants of survival.

Methods: We conducted a retrospective study using the Swedish national registry on infective endocarditis, which contains nationwide patient data. Read More

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http://openheart.bmj.com/lookup/doi/10.1136/openhrt-2018-000
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http://dx.doi.org/10.1136/openhrt-2018-000926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443117PMC
February 2019
1 Read

[Infective Endocarditis Causing Native and Prosthetic Heart Valve Dysfunction].

Kardiologiia 2019 Apr 13;59(3):68-77. Epub 2019 Apr 13.

Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo.

Infective endocarditis (IE) is the disease that has high inhospital mortality. Heart valves dysfunction - both native and prosthetic - is the primary IE complication requiring a surgical intervention. The IE causes and its course have been discussed in this review. Read More

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http://dx.doi.org/10.18087/cardio.2019.3.10245DOI Listing
April 2019
3 Reads

Biofilm formation by Staphylococcus aureus clinical isolates correlates with the infection type.

Infect Dis (Lond) 2019 Apr 15:1-6. Epub 2019 Apr 15.

a Department of Rheumatology and Inflammation Research , Institute of Medicine, Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden.

Background: Biofilms are involved in many Staphylococcus aureus infections, but relation of biofilm formation and the infection types or the clinical outcomes remain unclear.

Methods: We measured biofilm formation, with a microtiter plate assay, of a collection of methicillin-sensitive clinical isolates from 159 invasive S. aureus infections, encompassing all cases occurring within a hospital catchment area during two years, and from additional 49 non-invasive skin infections from the same region. Read More

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http://dx.doi.org/10.1080/23744235.2019.1593499DOI Listing
April 2019
3 Reads

Microbiological diagnostics of bloodstream infections in Europe - An ESGBIES survey.

Clin Microbiol Infect 2019 Apr 10. Epub 2019 Apr 10.

Institute of Medical Microbiology, University Hospital Münster, Münster, Germany. Electronic address:

Objectives: High-quality diagnosis of bloodstream infections (BSIs) is important for successful patient management. As knowledge on current practices of microbiological BSI diagnostics is limited, this project aimed to assess its current state in European microbiological laboratories.

Methods: We performed an online questionnaire-based cross-sectional survey comprising 34 questions on practices of microbiological BSI diagnostics. Read More

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http://dx.doi.org/10.1016/j.cmi.2019.03.024DOI Listing
April 2019
1 Read

AMPs as Anti-biofilm Agents for Human Therapy and Prophylaxis.

Adv Exp Med Biol 2019 ;1117:257-279

Department of Microbiology and Parasitology, University of Navarra, Pamplona, Spain.

Microbial cells show a strong natural tendency to adhere to surfaces and to colonize them by forming complex communities called biofilms. In this growth mode, biofilm-forming cells encase themselves inside a dense matrix which efficiently protects them against antimicrobial agents and effectors of the immune system. Moreover, at the physiological level, biofilms contain a very heterogeneous cell population including metabolically inactive organisms and persisters, which are highly tolerant to antibiotics. Read More

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http://link.springer.com/10.1007/978-981-13-3588-4_14
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http://dx.doi.org/10.1007/978-981-13-3588-4_14DOI Listing
January 2019
2 Reads

The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis.

Eur Heart J 2019 Apr 12. Epub 2019 Apr 12.

Duke University Medical Center, Durham, NC, USA.

Aims: In left-sided infective endocarditis (IE), a large vegetation >10 mm is associated with higher mortality, yet it is unknown whether surgery during the acute phase opposed to medical therapy is associated with improved survival. We assessed the association between surgery and 6-month mortality as related to vegetation size.

Methods And Results: Patients with definite, left-sided IE (2008-2012) from The International Collaboration on Endocarditis prospective, multinational registry were included. Read More

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http://dx.doi.org/10.1093/eurheartj/ehz204DOI Listing
April 2019
1 Read

Combination antifungal therapy for treatment of prosthetic valve endocarditis and utility of T2Candida Panel®: A case series.

IDCases 2019 19;15:e00525. Epub 2019 Mar 19.

New York University Langone Health, Department of Medicine, Division of Infectious Diseases, 550 First Avenue, New York, NY 10016, United States.

Although Candida species are common pathogens for nosocomial infections, Candida endocarditis is still considered a rare entity. Here, we report two cases of endovascular infections in patients with prosthetic valves, both of which responded to combination antifungal therapy without surgical intervention. Additionally, T2 magnetic resonance (T2MR) was used to assess for resolution of invasive candidiasis. Read More

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http://dx.doi.org/10.1016/j.idcr.2019.e00525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441745PMC
March 2019
1 Read

Eustachian valve infective endocarditis.

BMJ Case Rep 2019 Apr 11;12(4). Epub 2019 Apr 11.

Faculty of Medicine, Alexandria University, Alexandria, Egypt.

A 40-year-old woman presented with postoperative fever. Echocardiography revealed a large pedunculated cauliflower right atrial mass of heterogeneous echogenicity attached to the eustachian valve measuring about 2×3 cm. She underwent surgical excision, gross and microscopical examination were consistent with eustachian valve infective endocarditis. Read More

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http://dx.doi.org/10.1136/bcr-2018-228653DOI Listing
April 2019
1 Read

Infectious causes of stroke.

Curr Opin Infect Dis 2019 Apr 9. Epub 2019 Apr 9.

Cerebrovascular Center, Cleveland Clinic, Cleveland, Ohio, USA.

Purpose Of Review: Stroke continuous to be a leading cause of debility in the world. Infections have been associated with stroke, but are not considered as directly causal, and so they are not often included in the traditional stroke workup and management. They are especially important in patients with stroke of undetermined etiology, and in certain patient populations, such as young patients without traditional risk factors, and immunocompromised patients. Read More

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http://dx.doi.org/10.1097/QCO.0000000000000547DOI Listing
April 2019
1 Read

Right-sided endocarditis on Contegra tube in a complex cianotic congenital heart disease.

J Nucl Cardiol 2019 Apr 10. Epub 2019 Apr 10.

Department of Radiology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12350-019-01708-wDOI Listing
April 2019
1 Read

Acquired Infectious Defect in the Atrioventricular Septum: A Complication of Aortic Valve Endocarditis.

J Tehran Heart Cent 2018 Oct;13(4):193-194

Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450818PMC
October 2018
1 Read

Glomerulonephritis and nephrotic syndrome in a child with DiGeorge syndrome: Answers.

Pediatr Nephrol 2019 Apr 8. Epub 2019 Apr 8.

Wilf Children's Hospital, Pediatric Department, Shaare Zedek Medical Center, Shmuel Bait Street 12, 9103102, Jerusalem, Israel.

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http://dx.doi.org/10.1007/s00467-019-04243-5DOI Listing
April 2019
1 Read

Genomic analysis of multidrug-resistant clinical isolates for antimicrobial resistance genes and virulence factors from the western region of Saudi Arabia.

Antimicrob Resist Infect Control 2019 25;8:55. Epub 2019 Mar 25.

1Special Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, 21589 Saudi Arabia.

Background: is a ubiquitous member of the gut microbiota and has emerged as a life- threatening multidrug-resistant (MDR) nosocomial pathogen. The aim of this study was to survey the prevalence of multidrug-resistant and epidemiologically important strains of in the western region of Saudi Arabia using phenotypic and whole genome sequencing approaches.

Methods: In total, 155 patients positive for infection were included in this study. Read More

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http://dx.doi.org/10.1186/s13756-019-0508-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434864PMC
March 2019
1 Read

φSa3mw Prophage as a Molecular Regulatory Switch of β-toxin Production.

J Bacteriol 2019 Apr 8. Epub 2019 Apr 8.

Department of Microbiology and Immunology, University of Iowa, Roy J. and Lucille A. Carver College of Medicine, Iowa City, Iowa, USA

Phage regulatory switches (phage-RSs) are a newly described form of active lysogeny where prophages function as regulatory mechanisms for expression of chromosomally-encoded, bacterial genes. In φSa3int is a widely-distributed family of prophages that integrate into the β-toxin structural gene effectively inactivating it. However, β-toxin producing strains often arise during infections and are more virulent in experimental infective endocarditis and pneumonia infections. Read More

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http://jb.asm.org/lookup/doi/10.1128/JB.00766-18
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http://dx.doi.org/10.1128/JB.00766-18DOI Listing
April 2019
5 Reads

Daptomycin Dose-Ranging Evaluation with Single vs. Multi-Dose Ceftriaxone Combinations against in an Simulated Endocarditis Vegetation Model.

Antimicrob Agents Chemother 2019 Apr 8. Epub 2019 Apr 8.

Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Detroit, MI

The viridans group streptococci (VGS) are a heterogeneous group of organisms which are important components of the normal human oral flora. Among the VGS, the subgroup is one of the most common causes of infective endocarditis (IE). Daptomycin (DAP) is a potential alternative therapeutic option for invasive infections, given high rates of β-lactam resistance and vancomycin tolerance in such strains. Read More

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http://dx.doi.org/10.1128/AAC.00386-19DOI Listing
April 2019
4 Reads

Infective Endocarditis in the Intravenous Drug Use Population at a Tertiary Hospital in Melbourne, Australia.

Heart Lung Circ 2019 Feb 1. Epub 2019 Feb 1.

Department of Infectious Diseases, Alfred Hospital, Melbourne, Vic, Australia.

Background Infective endocarditis has been associated with underlying cardiac pathology and streptococci infections. Intravenous drug use (IVDU) is increasingly implicated as a contributing factor, resulting in a shift to a younger patient demographic, tricuspid valve involvement, severe staphylococcal infection, and unique management challenges. The objective of this study was to describe the clinical features, management and outcomes of patients with IVDU-associated infective endocarditis in the Australian context. Read More

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http://dx.doi.org/10.1016/j.hlc.2018.12.016DOI Listing
February 2019
1 Read

Acute kidney injury in infective endocarditis: A retrospective analysis.

Med Mal Infect 2019 Apr 4. Epub 2019 Apr 4.

Department of Infectious Diseases, University Hospital of Saint-Etienne, 42055 Saint-Etienne, France; EA 3064, GIMAP, Jean-Monnet University, University of Lyon, 42000 Saint-Etienne, France; CIC 1408 Inserm, 42055 Saint-Etienne, France.

Background: Acute kidney injury (AKI) is associated with high case fatality in infective endocarditis (IE), but epidemiological data on the frequency of AKI during IE is scarce. We aimed to describe the frequency and risk factors for AKI during the course of IE using Kidney Disease: Improving Global Outcomes consensual criteria.

Methods: Using the French hospital discharge database (French acronym PMSI), we retrospectively reviewed the charts of 112 patients presenting with a first episode of probable or definite IE between January 2010 and May 2015. Read More

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http://dx.doi.org/10.1016/j.medmal.2019.03.015DOI Listing
April 2019
2 Reads

Ceftaroline as salvage therapy for complicated MRSA bacteremia: case series and analysis.

Infection 2019 Apr 6. Epub 2019 Apr 6.

Division of Allergy, Immunology and Infectious Diseases, Department of Medicine, Rutgers Robert Wood Johnson Medical School, 1 Robert Wood Johnson Place, MEB 362, New Brunswick, NJ, 08901, USA.

Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI) is a major cause of morbidity and mortality in hospitalized patients. Ceftaroline fosamil (CPT) is the only available beta-lactam antibiotic with in vitro and in vivo activities against MRSA. There is currently limited clinical experience with CPT in complicated MRSA BSI. Read More

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http://dx.doi.org/10.1007/s15010-019-01304-7DOI Listing
April 2019
2 Reads

High Morbidity and Mortality Among Patients With Sentinel Admission for Injection Drug Use-Related Infective Endocarditis.

Open Forum Infect Dis 2019 Apr 1;6(4):ofz089. Epub 2019 Mar 1.

Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Background: Hospitalizations for individuals with injection drug use-related infective endocarditis (IDU-IE) represent an increasing portion of all patients with endocarditis. This study describes the evolving trends in demographics, clinical characteristics, rates of surgical intervention, and mortality among patients hospitalized with IE, comparing those with and without injection drug use.

Methods: This is a retrospective cohort study of patients admitted between January 1, 2007 to June 30, 2015 at a tertiary care center in Boston, Massachusetts. Read More

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https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofz08
Publisher Site
http://dx.doi.org/10.1093/ofid/ofz089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441563PMC
April 2019
1 Read

Lactococcus garvieae, an unusual pathogen in infective endocarditis: case report and review of the literature.

BMC Infect Dis 2019 Apr 3;19(1):301. Epub 2019 Apr 3.

Department of Internal Medicine, Division of Infectious Diseases, UTHealth - McGovern Medical School, Houston, TX, USA.

Background: Lactococcus garvieae is an unusual cause of infective endocarditis (IE). No current diagnostic and therapeutic guidelines are available to treat IE caused by these organisms. Based on a case report, we provide a review of the literature of IE caused by L. Read More

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http://dx.doi.org/10.1186/s12879-019-3912-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446321PMC
April 2019
2 Reads

A Case Series of Infection in Cancer Patients at an Academic Cancer Institute in the United States.

Infect Chemother 2019 Mar;51(1):45-53

Infectious Diseases and Hospital Epidemiologist, Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

Background: is a coagulase-negative staphylococcus (CoNS) that is a part of the normal human skin flora. Even though it belongs to CoNS family, it can cause severe and destructive infections in a similar fashion to . Skin and soft tissue infections (SSTI), bacteremia and endocarditis are amongst the most common clinical presentations. Read More

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http://dx.doi.org/10.3947/ic.2019.51.1.45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446009PMC
March 2019
4 Reads

Opioids and Infectious Diseases: A Converging Public Health Crisis.

J Infect Dis 2019 Apr 3. Epub 2019 Apr 3.

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda.

A converging public health crisis is emerging as the opioid epidemic is fueling a surge in infectious diseases, such as HIV/AIDS, the viral hepatitides, infective endocarditis, and skin and soft tissue infections (SSTIs). An integrated strategy is needed to tailor preventive and therapeutic approaches towards infectious diseases in people who misuse and/or are addicted to opioids and to concurrently address the underlying pre-disposing factor for the infections - opioid use disorder. This commentary highlights the unique and complimentary roles that the infectious diseases and substance use disorder communities can play in addressing this dual public health crisis. Read More

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http://dx.doi.org/10.1093/infdis/jiz133DOI Listing
April 2019
1 Read

Non-HACEK Gram-negative bacillus endocarditis.

Med Mal Infect 2019 Mar 30. Epub 2019 Mar 30.

Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey.

Patients And Methods: Retrospective analysis of clinical data using 26 diagnosed non-HACEK Gram-negative infective endocarditis cases from nine hospitals in Turkey.

Results: Mean age of patients was 53 (28-84) years, with a 23% case fatality. Nineteen (73%) of the 26 patients had at least one predisposing factor. Read More

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http://dx.doi.org/10.1016/j.medmal.2019.03.013DOI Listing
March 2019
1 Read

Draft Genome Sequence of Campylobacter fetus subsp. CITCf01, Isolated from a Patient with Subacute Bacterial Endocarditis.

Microbiol Resour Announc 2019 Mar 14;8(11). Epub 2019 Mar 14.

Department of Biological Sciences, Cork Institute of Technology, Bishopstown, Cork, Ireland.

is a Gram-negative, zoonotic pathogen and a member of the class We report the draft genome sequence of subsp. CITCf01, isolated from a patient with subacute bacterial endocarditis. CITCf01 grew under aerobic, microaerobic, and anaerobic conditions, and at 42°C, an unusual combination of growth conditions. Read More

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http://genomea.asm.org/lookup/doi/10.1128/MRA.01556-18
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http://dx.doi.org/10.1128/MRA.01556-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424209PMC
March 2019
8 Reads

Septic arthritis due to streptococci and enterococci in native joints: a 13 year retrospective study.

Infection 2019 Mar 30. Epub 2019 Mar 30.

Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St Gallen, Rorschacherstrasse 95, 9007, St. Gallen, Switzerland.

Objectives: Streptococcal species are the second most common cause of native joint septic arthritis (SA). However, there are few systematic data about streptococcal SA.

Methods: The medical records of adults with SA caused by streptococci, pneumococci, and enterococci at our tertiary care centre between 2003 and 2015 were reviewed. Read More

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http://dx.doi.org/10.1007/s15010-019-01301-wDOI Listing
March 2019
1 Read

Cefazolin versus anti-staphylococcal penicillins for the treatment of patients with Staphylococcus aureus bacteremia: a systematic review and meta-analysis.

Clin Microbiol Infect 2019 Mar 27. Epub 2019 Mar 27.

Institute for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany; Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany.

Background: For patients with bacteremia caused by methicillin-sensitive Staphylococcus aureus anti-staphylococcal penicillins (ASP) or cefazolin are agents of choice. While ASPs are potentially nephrotoxic, cefazolin may be less effective in some S. aureus strains due to an inoculum effect. Read More

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http://dx.doi.org/10.1016/j.cmi.2019.03.010DOI Listing
March 2019
2 Reads

Etiology, Risk Factors and Outcome of 1003 Cases of Infective Endocarditis from a 33-year National Survey in the Slovak Republic: An increasing proportion of elderly patients.

Neuro Endocrinol Lett 2019 Mar;39(8):544-549

North London Postgraduate Medical School, London, UK.

Background: Infective endocarditis (IE) is still a significant cause of mortality in European hospitals, despite of the fact, that large nationwide studies were performed in last twenty years and pathogens are well known. The aim of the study was to assess risk factors, mortality, etiology and proportion of elderly patients within a longitudinal nation wide survey of infectious endocarditis in Slovakia.

Patients And Methods: Etiology, risk factors and outcome of 1003 cases of infective endocarditis (IE) in Slovakia over the last 33 years have been assessed. Read More

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March 2019
2 Reads

Neurological Complications of Infective Endocarditis.

Curr Neurol Neurosci Rep 2019 Mar 30;19(5):23. Epub 2019 Mar 30.

Department of Neurosciences and Mental Health, Neurology Service, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal.

Purpose Of Review: The purpose of this narrative review and update is to summarize the current knowledge and provide recent advances on the neurologic complications of infective endocarditis.

Recent Findings: Neurological complications occur in about one-fourth of patients with infective endocarditis. Brain MRI represents a major tool for the identification of asymptomatic lesions, which occur in most of the patients with infective endocarditis. Read More

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http://dx.doi.org/10.1007/s11910-019-0935-xDOI Listing
March 2019
1 Read
3.059 Impact Factor

Escherichia coli endocarditis in an hemodialysis patient.

Med Mal Infect 2019 Mar 26. Epub 2019 Mar 26.

Department of bacteriology, University Hospital, 25000 Besançon, France.

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http://dx.doi.org/10.1016/j.medmal.2019.03.004DOI Listing
March 2019
1 Read

A short course of antibiotic treatment is safe after catheter withdrawal in catheter-related bloodstream infections due to coagulase-negative staphylococci.

Eur J Clin Microbiol Infect Dis 2019 May 28;38(5):977-983. Epub 2019 Mar 28.

Unit of Infectious Diseases, Instituto de Investigación Hospital "12 de Octubre" (imas12), University Hospital "12 de Octubre", Avenida de Córdoba, s/n, 28041, Madrid, Spain.

CoNS is the main cause of catheter-related bloodstream infections (CRBSI). Current guidelines recommend catheter withdrawal followed by antibiotics for at least 5 days. We aimed to assess the efficacy and safety of a shorter course of antibiotherapy in patients with CoNS CRBSI. Read More

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http://dx.doi.org/10.1007/s10096-019-03545-8DOI Listing
May 2019
1 Read

Variable Significance of Brain MRI Findings in Infective Endocarditis and Its Effect on Surgical Decisions.

Mayo Clin Proc 2019 Mar 25. Epub 2019 Mar 25.

Department of Neurology, Mayo Clinic, Rochester, MN.

Objective: To determine how brain magnetic resonance imaging (MRI) findings impact clinical outcomes in patients with infective endocarditis (IE) and to propose a management algorithm for patients with neurologic symptoms who are candidates for valve surgery (VS).

Patients And Methods: Data from our center were retrospectively reviewed for patients hospitalized with IE between January 1, 2007, and December 31, 2014. Outcomes were postoperative intracerebral hemorrhage (ICH), 6-month mortality, and functional outcome at last follow-up as described by the modified Rankin Scale (mRS) score. Read More

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http://dx.doi.org/10.1016/j.mayocp.2018.09.015DOI Listing
March 2019
2 Reads

Late prosthetic valve endocarditis with Mycobacterium tuberculosis after the Bentall procedure.

Ann Clin Microbiol Antimicrob 2019 Mar 28;18(1):15. Epub 2019 Mar 28.

Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.

Background: Prosthetic valve endocarditis (PVE) is a rare but severe complication of valve replacement surgery, with an incidence rate of 0.3-1.2% per patient-year. Read More

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http://dx.doi.org/10.1186/s12941-019-0314-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437957PMC
March 2019
9 Reads
1.514 Impact Factor

Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis.

BMC Infect Dis 2019 Mar 29;19(1):291. Epub 2019 Mar 29.

CIBER Enfermedades Respiratorias-CIBERES, Madrid, Spain.

Background: Streptococcus tigurinus was recently described as a new streptococcal species within the viridans group streptococci (VGS). The objectives of the present work were to analyse the clinical and microbiological characteristics of S. tigurinus isolated from patients with bacteraemias, to determine the prevalence of S. Read More

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http://dx.doi.org/10.1186/s12879-019-3914-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440093PMC
March 2019
1 Read

Addressing limitations of partial oral treatment of left-sided infectious endocarditis (POET) criteria for prosthetic valve endocarditis: a note of caution.

Eur Heart J 2019 Mar 27. Epub 2019 Mar 27.

Medical Faculty, Division of Cardiology, Pulmonology and Vascular Medicine, Heinrich-Heine-University Düsseldorf, Moorenstr. 5, Düsseldorf 40225, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehz163DOI Listing
March 2019
2 Reads

Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United States.

Case Rep Infect Dis 2019 19;2019:5369707. Epub 2019 Feb 19.

Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Q fever is a zoonotic bacterial infection caused by . Chronic Q fever comprises less than five percent of all Q fever cases and, of those, endocarditis is the most common presentation (up to 78% of cases), followed by vascular involvement. Risk factors for chronic Q fever with vascular involvement include previous vascular surgery, preexisting valvular defects, aneurysms, and vascular prostheses. Read More

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http://dx.doi.org/10.1155/2019/5369707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399537PMC
February 2019

Right-sided endocarditis from in a patient with tetralogy of Fallot.

Infect Dis Rep 2019 02 26;11(1):7872. Epub 2019 Feb 26.

Division of Pediatric Infectious Diseases.

Infective endocarditis is often caused by bacterial pathogens and can affect native and prosthetic tissue. Common pathogens in pediatric patients include , viridans group streptococci, enterococcal species and coagulase-negative staphylococci, though culture-negative cases are not uncommon. Coagulase-negative staphylococci present a conundrum to clinicians due to the potential of culture contamination. Read More

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http://dx.doi.org/10.4081/idr.2019.7872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397990PMC
February 2019
1 Read

Role of age and comorbidities in mortality of patients with infective endocarditis.

Authors:
Carlos Armiñanzas Concepción Fariñas-Alvarez Jesús Zarauza Patricia Muñoz Víctor González Ramallo Manuel Martínez Sellés José Mª Miró Meda Juan Manuel Pericás Miguel Ángel Goenaga Guillermo Ojeda Burgos Regino Rodríguez Álvarez Laura Castelo Corral Juan Gálvez-Acebal Francisco Javier Martínez Marcos Maria Carmen Fariñas Fernando Fernández Sánchez Mariam Noureddine Gabriel Rosas Javier de la Torre Lima José Aramendi Elena Bereciartua María José Blanco Roberto Blanco María Victoria Boado Marta Campaña Lázaro Alejandro Crespo Josune Goikoetxea José Ramón Iruretagoyena Josu Irurzun Zuazabal Leire López-Soria Miguel Montejo Javier Nieto David Rodrigo David Rodríguez Regino Rodríguez Yolanda Vitoria Roberto Voces Mª Victoria García López Radka Ivanova Georgieva Guillermo Ojeda Isabel Rodríguez Bailón Josefa Ruiz Morales Ana María Cuende Tomás Echeverría Ana Fuerte Eduardo Gaminde Miguel Ángel Goenaga Pedro Idígoras José Antonio Iribarren Alberto Izaguirre Yarza Xabier Kortajarena Urkola Carlos Reviejo Rafael Carrasco Vicente Climent Patricio Llamas Esperanza Merino Joaquín Plazas Sergio Reus Nemesio Álvarez José María Bravo-Ferrer Laura Castelo José Cuenca Pedro Llinares Enrique Miguez Rey María Rodríguez Mayo Efrén Sánchez Dolores Sousa Regueiro Francisco Javier Martínez Mª Del Mar Alonso Beatriz Castro Dácil García Rosado Mª Del Carmen Durán Mª Antonia Miguel Gómez Juan Lacalzada Ibrahim Nassar Antonio Plata Ciezar José Mª Reguera Iglesias Víctor Asensi Álvarez Carlos Costas Jesús de la Hera Jonnathan Fernández Suárez Lisardo Iglesias Fraile Víctor León Arguero José López Menéndez Pilar Mencia Bajo Carlos Morales Alfonso Moreno Torrico Carmen Palomo Begoña Paya Martínez Ángeles Rodríguez Esteban Raquel Rodríguez García Mauricio Telenti Asensio Manuel Almela Juan Ambrosioni Manuel Azqueta Mercè Brunet Marta Bodro Ramón Cartañá Carlos Falces Guillermina Fita David Fuster Cristina García de la Mària Marta Hernández-Meneses Jaume Llopis Pérez Francesc Marco José M Miró 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Oscar García Uriarte Alejandro Martín López Zuriñe Ortiz de Zárate José Antonio Urturi Matos Gloria García Domínguez Antonio Sánchez-Porto José Mª Arribas Leal Elisa García Vázquez Alicia Hernández Torres Ana Blázquez Gonzalo de la Morena Valenzuela Ángel Alonso Javier Aramburu Felicitas Elena Calvo Anai Moreno Rodríguez Paola Tarabini-Castellani Eva Heredero Gálvez Carolina Maicas Bellido José Largo Pau Mª Antonia Sepúlveda Pilar Toledano Sierra Sadaf Zafar Iqbal-Mirza Eva Cascales Alcolea Pilar Egea Serrano José Joaquín Hernández Roca Ivan Keituqwa Yañez Ana Peláez Ballesta Víctor Soriano Eduardo Moreno Escobar Alejandro Peña Monje Valme Sánchez Cabrera David Vinuesa García María Arrizabalaga Asenjo Carmen Cifuentes Luna Juana Núñez Morcillo Mª Cruz Pérez Seco Aroa Villoslada Gelabert Carmen Aured Guallar Nuria Fernández Abad Pilar García Mangas Marta Matamala Adell Mª Pilar Palacián Ruiz Juan Carlos Porres Begoña Alcaraz Vidal Nazaret Cobos Trigueros María Jesús Del Amor Espín José Antonio Giner Caro Roberto Jiménez Sánchez Amaya Jimeno Almazán Alejandro Ortín Freire Monserrat Viqueira González Pere Pericás Ramis Mª Ángels Ribas Blanco Enrique Ruiz de Gopegui Bordes Laura Vidal Bonet Mª Carmen Bellón Munera Elena Escribano Garaizabal Antonia Tercero Martínez Juan Carlos Segura Luque

Eur J Intern Med 2019 Mar 20. Epub 2019 Mar 20.

Complejo Hospitalario Universitario de Albacete Albacete, Spain.

Purpose: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality.

Methods: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09536205193008
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http://dx.doi.org/10.1016/j.ejim.2019.03.006DOI Listing
March 2019
5 Reads

Whipple's endocarditis diagnosed by thrombus analysis retrieved by successful mechanical thrombectomy.

J Neurol Sci 2019 May 14;400:42-43. Epub 2019 Mar 14.

Stroke Unit, Department of Neurology, Hôpital Pierre Wertheimer, Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2019.03.009DOI Listing
May 2019
1 Read

Group C Streptococcus dysgalactiae subsp.equisimilis (SDSE) Endocarditis with Endogenous Endophthalmitis and Aortic Root Abscess.

IDCases 2019 26;15:e00513. Epub 2019 Feb 26.

James J. Peters VA Medical Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

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http://dx.doi.org/10.1016/j.idcr.2019.e00513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409387PMC
February 2019
1 Read

Treatment of a cervical epidural abscess.

BMJ Case Rep 2019 Mar 20;12(3). Epub 2019 Mar 20.

Department of Neurological Surgery, Henry Ford Hospital, Detroit, Michigan, USA.

First reported in 1988, is a virulent coagulase-negative species often associated with endocarditis. This is the first case report describing this infection in the cervical spine. A 58-year-old, left-handed Caucasian woman with no significant medical history presented with neck and left arm pain. Read More

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http://dx.doi.org/10.1136/bcr-2018-227449DOI Listing
March 2019
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Blocking a rash diagnosis: a rare case of infective endocarditis.

BMJ Case Rep 2019 Mar 20;12(3). Epub 2019 Mar 20.

Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

We report a case of a previously healthy, afebrile patient who presented with subacute bilateral lower extremity rash and complete heart block, which was later found to be secondary to infective endocarditis. His transoesophageal echocardiogram detected multiple vegetations and blood cultures were positive for , a nutritionally variant streptococcus that is a normal component of oral flora and thought to be responsible for approximately 5% of all cases of streptococcal endocarditis. Due to concerns for renal failure, the patient was treated with an unconventional regimen of ampicillin and ceftriaxone. Read More

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http://dx.doi.org/10.1136/bcr-2018-226213DOI Listing
March 2019
3 Reads

Infections and outcomes after cardiac surgery-The impact of outbreaks traced to transesophageal echocardiography probes.

Acta Anaesthesiol Scand 2019 Mar 19. Epub 2019 Mar 19.

Department of Anaesthesia and Intensive Care, Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland.

Background: Infections are a frequent complication of cardiac surgery. The intraoperative use of transesophageal echocardiography (TEE) may be an underrecognized risk factor for post-operative infections. The aim of this study was to investigate infection rates and outcomes after cardiac surgery in a nationwide cohort, especially in relation to periods where surface damaged TEE probes were used. Read More

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http://dx.doi.org/10.1111/aas.13360DOI Listing
March 2019
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Myocarditis Caused by in the Absence of Endocarditis: Case Report and Review of the Literature.

Case Rep Med 2019 10;2019:3701016. Epub 2019 Feb 10.

Internal Medicine Department, University Hospital of Patras, Rio, Greece.

Brucellosis remains an important public health problem with endemic characteristics in many countries. Brucellosis can affect almost all organs and systems of human body. Cardiac complications are unusual, occurring in less than 2% of patients and usually manifest as endocarditis. Read More

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http://dx.doi.org/10.1155/2019/3701016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387729PMC
February 2019
1 Read

Prosthetic Valve Legionella Endocarditis.

Ann Thorac Surg 2019 Mar 14. Epub 2019 Mar 14.

Department of Cardiovascular and Thoracic Surgery, Hofstra Northwell School of Medicine, Manhasset, NY.

This is a case report of an 80 year old man with culture-negative prosthetic valve endocarditis who was ultimately diagnosed with Legionella pneumophila endocarditis. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2019.02.006DOI Listing
March 2019
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Tc-Besilesomab-SPECT/CT in Infectious Endocarditis: Upgrade of a Forgotten Method?

Front Med (Lausanne) 2019 27;6:40. Epub 2019 Feb 27.

Department of Nuclear Medicine, Georg-August-University Göttingen, Göttingen, Germany.

Infective endocarditis displays a serious condition with high mortality rates. Establishing a reliable diagnosis can be challenging. This study evaluates granulocyte imaging with Tc-Besilesomab-SPECT/CT in order to determine the clinical value of the method and its possible redefinition through the addition of hybrid imaging. Read More

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http://dx.doi.org/10.3389/fmed.2019.00040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402384PMC
February 2019
1 Read

Medical complications of opioid use disorder in pregnancy.

Semin Perinatol 2019 Jan 14. Epub 2019 Jan 14.

UNLV School of Medicine, Las Vegas, NV, United States.

Women with opioid use disorder are at increased risk of other medical complications of pregnancy. Providing care for such complex patients requires the ability to 1) acknowledge addiction as a chronic disease, 2) incorporate the altered physiology of pregnancy, and 3) devise a treatment plan that can effectively manage acute conditions. A basic tenet of care is rooted in experience, rather than evidence, but includes stabilization of opiate use disorder (OUD) as a primary goal of management of other medical complications of pregnancy. Read More

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http://dx.doi.org/10.1053/j.semperi.2019.01.005DOI Listing
January 2019
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Cutaneous infection by Phaeoacremonium parasiticum.

Rev Iberoam Micol 2019 Mar 7. Epub 2019 Mar 7.

Department of Microbiology, Hospital Clínic, Universitat de Barcelona, ISGLOBAL, Barcelona, Spain.

Background: Phaeoacremonium parasiticum is considered a rare infectious agent that is part of a heterogeneous group of fungi causing phaeohyphomycosis. This organism is capable of producing subcutaneous infections, eumycetomas, osteomyelitis, arthritis, myositis and also disseminated diseases, such as fungemia and endocarditis.

Case Report: We describe a case of cutaneous infection by P. Read More

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http://dx.doi.org/10.1016/j.riam.2018.10.003DOI Listing
March 2019
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In-host evolution of Staphylococcus epidermidis in a pacemaker-associated endocarditis resulting in increased antibiotic tolerance.

Nat Commun 2019 03 8;10(1):1149. Epub 2019 Mar 8.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, 8091, Zurich, Switzerland.

Treatment failure in biofilm-associated bacterial infections is an important healthcare issue. In vitro studies and mouse models suggest that bacteria enter a slow-growing/non-growing state that results in transient tolerance to antibiotics in the absence of a specific resistance mechanism. However, little clinical confirmation of antibiotic tolerant bacteria in patients exists. Read More

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http://dx.doi.org/10.1038/s41467-019-09053-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408453PMC
March 2019
3 Reads

Pauci-immune proliferative glomerulonephritis and fungal endocarditis: More than a mere coincidence?

BMJ Case Rep 2019 Mar 6;12(3). Epub 2019 Mar 6.

Medicine/Nephrology, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1136/bcr-2018-229059DOI Listing
March 2019
1 Read