8,231 results match your criteria Infectious Endocarditis


Factors associated with readmission and mortality in adult patients with skin and soft tissue infections.

Int J Dermatol 2019 Feb 15. Epub 2019 Feb 15.

Clinical Microbiology Department, Son Llàtzer Hospital, Balearic Islands, Spain.

Background: Skin and soft tissue infections (SSTIs) are a common cause of consultation, and complicated cases require hospitalization. We describe factors that are related to readmission and/or mortality of hospitalized patients diagnosed with SSTIs.

Methods: Retrospective review of hospital-admitted patients with a diagnosis of cellulitis, abscess, hidradenitis, fasciitis, and Fournier's gangrene. Read More

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http://dx.doi.org/10.1111/ijd.14390DOI Listing
February 2019

[Microflora of peripheral blood obtained from patients with infective endocarditis.]

Klin Lab Diagn 2018 ;63(10):636-640

The Federal State Budget Scientific Institution «Research Institute for Complex Issues of Cardiovascular Diseases», 650002, Kemerovo, Russia.

Infective endocarditis is a serious inflammatory disease associated with damage of heart valves and other parts of endocardium. This study included 91 patients with a confirmed diagnosis of «infectious endocarditis» and hospitalized at the Research Institute of Complex Problems of Cardiovascular Disease (Kemerovo, Russia) from 2010 to 2015. The determination of the spectrum of microorganisms in the samples of patients' peripheral blood was carried out using the PCR method using reagents produced by Lyteh Ltd. Read More

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http://dx.doi.org/10.18821/0869-2084-2018-63-10-636-640DOI Listing
January 2018

Neutrophil to Lymphocyte Ratio and Mortality in Spinal Epidural Abscess.

Spine J 2019 Feb 11. Epub 2019 Feb 11.

Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School. Electronic address:

Background Context: Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio have been previously identified as markers for overall survival in oncology but remain heretofore unexplored in spinal epidural abscess (SEA).

Purpose: The purpose of this study was to determine the impact of these routinely collected assessments on ninety-day mortality in SEA.

Study Design/setting: Retrospective, case-control study PATIENT SAMPLE: Patients 18 years or older diagnosed with SEA at two academic medical centers and three community hospitals OUTCOME MEASURES: Ninety-day post-discharge and in-hospital mortality METHODS: Complete blood count with differential obtained on the day immediately preceding or on the day of admission was used to calculate platelet to lymphocyte and neutrophil to lymphocyte ratios. Read More

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http://dx.doi.org/10.1016/j.spinee.2019.02.005DOI Listing
February 2019

Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Presenting After the Initiation of Staphylococcus hominis Infectious Endocarditis Treatment: A Case Report and Updated Review of Management Considerations.

Cureus 2018 Dec 4;10(12):e3679. Epub 2018 Dec 4.

Internal Medicine, University of Central Florida College of Medicine, Orlando, USA.

We present the case of a 62-year-old Caucasian man who was being treated for mitral valve endocarditis via a six-week course of vancomycin. On Day 32 of the treatment, he developed an erythematous, pruritic, desquamating, and painful rash covering 80% of the total body surface area and intermittent fevers. Laboratory findings included leukocytosis with peripheral blood eosinophilia and elevated erythrocyte sedimentation rate, C-reactive protein, and serum creatinine. Read More

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http://dx.doi.org/10.7759/cureus.3679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367119PMC
December 2018
2 Reads

Methicillin-Resistant Staphylococcus aureus Prosthetic Valve Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management.

Clin Microbiol Rev 2019 Mar 13;32(2). Epub 2019 Feb 13.

Division of Infectious Diseases, Medicine Department, Massachusetts General Hospital, Boston, Massachusetts, USA.

SUMMARY prosthetic valve endocarditis (PVE) remains among the most morbid bacterial infections, with mortality estimates ranging from 40% to 80%. The proportion of PVE cases due to methicillin-resistant (MRSA) has grown in recent decades, to account for more than 15% of cases of PVE and 6% of all cases of PVE. Because no large studies or clinical trials for PVE have been published, most guidelines on the diagnosis and management of MRSA PVE rely upon expert opinion and data from animal models or related conditions (e. Read More

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http://dx.doi.org/10.1128/CMR.00041-18DOI Listing

Utility of qSOFA score in identifying patients at risk for poor outcome in Staphylococcus aureus bacteremia.

BMC Infect Dis 2019 Feb 13;19(1):149. Epub 2019 Feb 13.

Department of Clinical Pharmacy, University of Southern California School of Pharmacy, 1985 Zonal Ave, Los Angeles, CA, 90089, USA.

Background: The prognostic capability of the quick Sequential Organ Failure Assessment (qSOFA) bedside scoring tool is uncertain in non-ICU patients with sepsis due to bacteremia given the low number of patients previously evaluated.

Methods: We performed a retrospective cohort study of adult hospitalized patients with Staphylococcus aureus bacteremia (SAB). Medical charts were reviewed to determine qSOFA score, systemic inflammatory response syndrome (SIRS) criteria, and Pitt bacteremia score (PBS) at initial presentation; their predictive values were compared for ICU admission within 48 h, ICU stay duration > 72 h, and 30-day mortality. Read More

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http://dx.doi.org/10.1186/s12879-019-3770-4DOI Listing
February 2019

Successful cure of daptomycin-non-susceptible, vancomycin-intermediate Staphylococcus aureus prosthetic aortic valve endocarditis directed by synergistic in vitro time-kill study.

Infect Dis (Lond) 2019 Feb 14:1-6. Epub 2019 Feb 14.

d Department of Pharmacy , Veterans Administration Western New York Healthcare System , Buffalo , NY , USA.

Infectious complications following surgical valve replacements are extremely difficult to treat, often requiring prolonged antimicrobials therapy with or without surgery. Vancomycin-intermediate Staphylococcus aureus is an infrequent pathogen, with an estimated prevalence of less than 0.3%, but presents even greater challenges. Read More

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http://dx.doi.org/10.1080/23744235.2018.1533646DOI Listing
February 2019

Contemporary management of cardiac implantable electronic device infection.

Heart 2019 Feb 12. Epub 2019 Feb 12.

Department of Cardiovascular Diseases, Mayo Clinic Arizona, Phoenix, Arizona, USA.

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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2017-312146
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http://dx.doi.org/10.1136/heartjnl-2017-312146DOI Listing
February 2019
1 Read

Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research.

Nat Rev Microbiol 2019 Feb 8. Epub 2019 Feb 8.

Duke University Medical Center, Durham, NC, USA.

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern pathogens. The same organism that lives as a commensal and is transmitted in both health-care and community settings is also a leading cause of bacteraemia, endocarditis, skin and soft tissue infections, bone and joint infections and hospital-acquired infections. Genetically diverse, the epidemiology of MRSA is primarily characterized by the serial emergence of epidemic strains. Read More

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http://dx.doi.org/10.1038/s41579-018-0147-4DOI Listing
February 2019
1 Read

Endocarditis following IUD insertion in a patient with tetralogy of Fallot.

BMJ Case Rep 2019 Feb 7;12(2). Epub 2019 Feb 7.

Department of Medicine, University of Washington, Seattle, Washington, USA.

The role of antibiotic prophylaxis for prevention of infective endocarditis is unknown. Endocarditis prophylaxis is recommended for certain high-risk individuals prior to dental procedures. To our knowledge, this is the first case reported in the literature of a patient with complex congenital heart disease developing endocarditis in the period immediately following otherwise uncomplicated intrauterine device insertion. Read More

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http://dx.doi.org/10.1136/bcr-2018-227962DOI Listing
February 2019
1 Read

Subclinical thrombus formation in bioprosthetic pulmonary valve conduits.

Int J Cardiol 2019 Jan 30. Epub 2019 Jan 30.

Pediatric Cardiology and Intensive Care, University Medical Center Göttingen, Germany. Electronic address:

Objectives: Bioprosthetic pulmonary valve conduits have been reported with an increased risk of endocarditis. Thrombus formation is considered as source of these serious and life-threatening infections. We reviewed a series of explanted valved pulmonary conduits for histological evidence for thrombus formation. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.01.095DOI Listing
January 2019
1 Read

Clinical Outcomes of Infective Endocarditis in Injection Drug Users.

J Am Coll Cardiol 2019 Feb;73(5):559-570

Cardiovascular Outcomes Research Laboratories, Division of Cardiac Surgery, David Geffen School of Medicine, University of California, Los Angeles, California. Electronic address:

Background: Rising rates of hospitalization for infective endocarditis (IE) have been increasingly tied to rising injection drug use (IDU) associated with the opioid epidemic.

Objectives: This study analyzed recent trends in IDU-IE hospitalization and characterized outcomes and readmissions for IDU-IE patients.

Methods: The authors evaluated the National Readmissions Database (NRD) for IE cases between January 2010 and September 2015. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.10.082DOI Listing
February 2019
2 Reads

[Pediatric clinical experience in infectious endocarditis due to Candida spp].

Rev Chilena Infectol 2018 ;35(5):553-559

Departamento de Infectología Pediátrica, Hospital Civil de Guadalajara "Fray Antonio Alcalde", México.

Background: Treatment and outcome of Candida spp infectious endocarditis in children it most be based on treatment guidelines, however there are some controversies.

Aim: To describe our experience on treatment of pediatric candidal infective endocarditis.

Methods: Analytic prospective study, from January 2006 to December 2017. Read More

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http://dx.doi.org/10.4067/s0716-10182018000500553DOI Listing
January 2018
1 Read

Similarities and differences in antimicrobial prescribing between major city hospitals and regional and remote hospitals in Australia.

Int J Antimicrob Agents 2019 Feb 26;53(2):171-176. Epub 2018 Oct 26.

National Centre for Antimicrobial Stewardship, Peter Doherty Research Institute for Infection and Immunity, Melbourne, VIC, Australia; University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences, Department of Medicine - Royal Melbourne Hospital, Melbourne, VIC, Australia; Victorian Infectious Diseases Service, Royal Melbourne Hospital, Melbourne, VIC, Australia.

Many regional and remote hospitals (RRHs) do not have the specialist services that usually support antimicrobial stewardship (AMS) programmes in major city hospitals. It is not known if this is associated with higher rates of inappropriate antimicrobial prescribing. The aim of this study was to identify similarities and differences in antimicrobial prescribing patterns between major city hospitals and RRHs in Australia. Read More

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http://dx.doi.org/10.1016/j.ijantimicag.2018.10.009DOI Listing
February 2019
2 Reads

[Management of infective endocarditis].

Lakartidningen 2019 Feb 5;116. Epub 2019 Feb 5.

Uppsala Universitet - Centrum för forskning och utveckling, Region Gävleborg/Gävle Uppsala, Sweden Uppsala Universitet - Centrum för forskning och utveckling, Region Gävleborg/Gävle Uppsala, Sweden.

Infective endocarditis is an uncommon but potentially lethal disease, defined as an infectious lesion of the endocardium. The possibility of infective endocarditis should be considered in all patients with gram positive bacteremia. Particular consideration is recommended in case of Staphylococcus aureus bacteremia. Read More

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February 2019
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Effect of the type of surgical indication on mortality in patients with infective endocarditis who are rejected for surgical intervention.

Int J Cardiol 2019 Jan 10. Epub 2019 Jan 10.

Servicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.

Aim: To evaluate the effect of the type of surgical indication on mortality in infective endocarditis (IE) patients who are rejected for surgery.

Methods And Results: From January 2008 to December 2016, 2714 patients with definite left-sided IE were attended in the participating hospitals. One thousand six hundred and fifty-three patients (60. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01675273183409
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http://dx.doi.org/10.1016/j.ijcard.2019.01.014DOI Listing
January 2019
4 Reads

Infection in the clinic of internal diseases.

Ter Arkh 2018 Nov;90(11):112-119

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia.

In the modern clinic of internal diseases, the specific gravity of the infectious pathology, manifested by various clinical syndromes, is increasing. Infectious pathology is represented by diseases of the respiratory system, heart disease (infective endocarditis, cardioimplant infections, viral myocarditis), infectious arthropathies, extrahepatic manifestations of viral hepatitis, cytopenic syndromes, various manifestations of sepsis and some other conditions.In most cases, the diagnosis and management of such patients is the responsibility of the internist, who must be able to suspect the infection and carry out its verification. Read More

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http://dx.doi.org/10.26442/terarkh20189011112-119DOI Listing
November 2018
1 Read

Abscess of the spleen in a patient with infectious endocarditis.

Ter Arkh 2018 Nov;90(11):98-101

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia.

A patient with infective endocarditis (IE), complicated by the development of the abscess of the spleen, is described. The diagnosis of IE was verified several months after the onset of clinical symptoms (fever, hemorrhagic skin rashes, splenomegaly).The patient suspected hemorrhagic vasculitis and lymphoma of the spleen, which were not confirmed. Read More

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http://dx.doi.org/10.26442/terarkh2018901198-101DOI Listing
November 2018
2 Reads

Simultaneous breast and pacemaker infection.

IDCases 2019 9;15:e00485. Epub 2019 Jan 9.

Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

Infection with spp. is endemic to the Middle East and the eastern Mediterranean basin. Brucellosis can mimic infectious and non-infectious febrile illnesses and therefore it can pose a diagnostic challenge. Read More

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http://dx.doi.org/10.1016/j.idcr.2019.e00485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348196PMC
January 2019
1 Read

Partial Oral Therapy for Osteomyelitis and Endocarditis - Is It Time?

Authors:
Helen W Boucher

N Engl J Med 2019 01;380(5):487-489

From the Tufts Center for Integrated Management of Antimicrobial Resistance and Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center and Tufts University School of Medicine, Boston.

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http://dx.doi.org/10.1056/NEJMe1817264DOI Listing
January 2019
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The risk of infective endocarditis among people who inject drugs: a retrospective, population-based time series analysis.

CMAJ 2019 Jan;191(4):E93-E99

ICES (Weir, Slater, Jandoc, Garg); Departments of Epidemiology and Biostatistics (Weir, Garg) and Family Medicine (Koivu), and Divisions of Nephrology (Weir, Garg) and Infectious Diseases (Silverman), Department of Medicine, Western University, London, Ont.

Background: Infective endocarditis is an increasingly common complication among people who inject drugs. We conducted this study to determine whether the removal of traditional controlled-release oxycodone from the Canadian market would be associated with an increase in the use of hydromorphone and an increased risk of infective endocarditis.

Methods: We conducted a retrospective, population-based time series analysis using the linked health administrative databases of Ontario, Canada. Read More

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http://dx.doi.org/10.1503/cmaj.180694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342696PMC
January 2019
1 Read

Mitral Valve Endocarditis: A rare Manifestation of Lyme Disease.

Ann Thorac Surg 2019 Jan 25. Epub 2019 Jan 25.

Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, Ohio.

Valvular involvement in Lyme disease is rare. Confirmation of Borrelia species as the causative agent by Polymerase Chain Reaction (PCR) was done in a few cases in Europe and the US. We describe a case of mitral regurgitation with a preoperative diagnosis of myxomatous mitral valve degeneration. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2018.12.046DOI Listing
January 2019
1 Read

[The study of activity of matrix metalloproteinases abd reactants of inflammation in patients with endocarditis.]

Klin Lab Diagn 2018 ;63(5):272-276

"The Research Institute of Therapy and Preventive Medicine"-The Branch of The Federal State Budget Scientific Institution "The Federal Research Center "The Institute of Cytology and genetics" of the Siberian Branch of the Russian Academy of Sciences", 630089, Novosibirsk, Russia.

The purpose of study is to establish and compare concentration of acute-phase indices, total activity of matrix metalloproteinases-2, -7 (MMP-2, MMP-7) of blood serum in patients with vegetations on heart valvular apparatus of infectious and noninfectious nature; to apply a correlation analysis between these indices; to evaluate advantages of technique of detection of total activity of MMP-2 and MMP-7 in patients with endocarditis of various etiology. The sampling consisted of 175 examined patients separated on two groups. The first group included 81 patients with noninfectious endocarditis; the second group included 94 patients with infectious endocarditis. Read More

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http://dx.doi.org/10.18821/0869-2084-2018-63-5-272-276DOI Listing
January 2018
1 Read

Distribution of virulence genes in bacteremic methicillin-resistant Staphylococcus aureus isolates from various sources.

J Microbiol Immunol Infect 2019 Jan 10. Epub 2019 Jan 10.

Division of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan; School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.

Background/purpose: Methicillin-resistant Staphylococcus aureus (MRSA) can encode proteins which directly bind bacteria to many tissues and medical devices or catheters to trigger pathogenesis. However, the relationship between genetic backgrounds and virulent factors in MRSA isolates remained incompletely understood yet.

Methods: MRSA isolates were collected from blood cultures of patients with infective endocarditis, bone/joint infection, skin/soft tissue infection, or catheter-related bacteremia in hemodialysis at a tertiary medical center between 2005 and 2011. Read More

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http://dx.doi.org/10.1016/j.jmii.2019.01.001DOI Listing
January 2019
1 Read

Intravenous and intraventricular daptomycin plus intravenous linezolid treatment of an infant with Vancomycin-Resistant Enterococci induced ventriculoperitoneal shunt infection.

World Neurosurg 2019 Jan 24. Epub 2019 Jan 24.

Departments of Pediatric Infectious Diseases, University of Health Sciences, Sisli Hamidiye Etfal Research and Education Hospital, Istanbul, Turkey.

The rate of ventriculoperitoneal (VP) shunt infection is reported between 3% and 20%. Vancomycin-Resistant Enterococci (VRE) are increasingly prevalent nasocomial pathogens worldwide and they rarely cause infections to the central nervous system. Daptomycin is a cyclic lipopeptide effective antibiotic due to its rapid bactericidal effect. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.065DOI Listing
January 2019
2 Reads

[Infective endocarditis in Morocco through the experience of a hospital department].

Ann Cardiol Angeiol (Paris) 2019 Jan 22. Epub 2019 Jan 22.

Service de cardiologie B, centre hosipitalier universitaire Ibn Sina, Rabat, Maroc.

Infective endocarditis is a grave disease because of a high level of morbidity and mortality. We conducted a retrospective analysis of 100 patients hospitalized for infective endocarditis from January 2009 until December 2015. The mean age was 41 years with a male predominance. Read More

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http://dx.doi.org/10.1016/j.ancard.2018.10.014DOI Listing
January 2019
1 Read

Impact of pre-operative antimicrobial treatment on microbiological findings from endocardial specimens in infective endocarditis.

Eur J Clin Microbiol Infect Dis 2019 Mar 24;38(3):497-503. Epub 2019 Jan 24.

Department of Infectious Diseases, Inflammation Center, Helsinki University Hospital (HUH) and University of Helsinki, Meilahti Triangle Hospital, open-plan office, 1st floor, P.O. BOX 372, 00029, Helsinki, Finland.

Treatment of infective endocarditis (IE) should be initiated promptly. This might hamper the chances to identify the causative organism in blood cultures. Microbiological sampling of infected valve in patients undergoing surgery might identify the causative organism. Read More

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http://dx.doi.org/10.1007/s10096-018-03451-5DOI Listing
March 2019
1 Read

Infective endocarditis caused by Streptococcus agalactiae: time for beta-hemolytic streptococci to follow treatment recommendations for S. aureus?

Authors:
Parham Sendi

Eur J Clin Microbiol Infect Dis 2019 Mar;38(3):419-422

Institute for Infectious Diseases, University of Bern, Friedbühlstrasse, 51, CH-3001, Bern, Switzerland.

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http://dx.doi.org/10.1007/s10096-018-03446-2DOI Listing
March 2019
1 Read

Microbial Epidemiology of Infectious Endocarditis in the Intravenous Drug Abuse Population: A Retrospective Study.

Infect Dis Ther 2019 Mar 23;8(1):113-118. Epub 2019 Jan 23.

The University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.

Introduction: The microbial epidemiology differs between infective endocarditis (IE) patients with and without a history of injection drug use. We set out to determine the prevalence and microbial epidemiology of infective endocarditis in our region, the Southeastern USA, to determine if any changes need to be made in empiric antimicrobial treatment.

Methods: The electronic medical record was reviewed for patients with IE between January 2013 and July 2017, which revealed 299 cases. Read More

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http://dx.doi.org/10.1007/s40121-019-0232-7DOI Listing
March 2019
1 Read

The Anti-Staphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood to Potentiate MRSA Bacteriolysis.

Antimicrob Agents Chemother 2019 Jan 22. Epub 2019 Jan 22.

ContraFect Corporation, Yonkers, NY

Bacteriophage-derived lysins are cell wall hydrolytic enzymes which represent a potential new class of antibacterial therapeutics in development to address burgeoning antimicrobial resistance. CF-301, the lead compound in this class, is in clinical development as an adjunctive treatment to potentially improve clinical cure rates of bacteremia and infective endocarditis (IE) when used in addition to antibiotics. In order to profile CF-301's activity in a clinically relevant milieu, we assessed its activity in human blood vs. Read More

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http://dx.doi.org/10.1128/AAC.02291-18DOI Listing
January 2019
1 Read

Mitral valve repair in infective endocarditis is not inferior to valve replacement: results from a Spanish nationwide prospective registry.

Gen Thorac Cardiovasc Surg 2019 Jan 21. Epub 2019 Jan 21.

Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Introduction: Infective endocarditis (IE) still carries high morbidity and mortality and frequently requires surgery. The benefit of mitral valve repair (MVr) in the setting of IE is yet to be proven. The goal of this study was to assess the results of MVr in patients with IE after a minimum follow-up of 1 year. Read More

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http://link.springer.com/10.1007/s11748-019-01063-0
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http://dx.doi.org/10.1007/s11748-019-01063-0DOI Listing
January 2019
4 Reads

[CHRONIC Q FEVER IN PATIENTS AT THE HILLEL YAFFE MEDICAL CENTER - THREE YEARS OF FOLLOW UP].

Harefuah 2019 Jan;158(1):12-15

Infectious Diseases Unit, Hillel Yaffe Medical Center, Hadera.

Introduction: Q fever is an acute zoonotic infection, which in some cases is complicated by a chronic disease. Diagnosis is based on serology, and in patients with a chronic disease, the source of infection must be investigated.

Aims: To describe patients with chronic Q fever, who were treated at the Hillel Yaffe Medical Center: risk factors, course of the disease, and serological findings. Read More

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January 2019
5 Reads

Acute Development and Rupture of a Basilar Tip Mycotic Aneurysm.

World Neurosurg 2019 Jan 17. Epub 2019 Jan 17.

Department of Neurosurgery, Geisinger, Danville, PA.

Infectious intracranial aneurysms (IIA) are rare but encountered when associated with rupture or detected on screening of high risk patients. The time course of the development of these aneurysms is unknown. Ultimately, the data published on mycotic aneurysms are in the form of case series, retrospective studies, with one recent systematic review, all of which have difficulty defining specifics regarding aneurysmal formation in these patients. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.12.211DOI Listing
January 2019
1 Read

Outpatient parenteral antibiotic treatment (OPAT) for infective endocarditis: Insights from the real life.

Clin Infect Dis 2019 Jan 14. Epub 2019 Jan 14.

Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France.

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http://dx.doi.org/10.1093/cid/ciz027DOI Listing
January 2019
1 Read

Candida parapsilosis: An Unusual Cause of Infective Endocarditis.

Cureus 2018 Nov 6;10(11):e3553. Epub 2018 Nov 6.

Cardiology, University of Missouri / St. Luke's Health System, Kansas City, USA.

Fungal endocarditis (FE) is a rare form of infectious endocarditis caused by fungi. Herein, we report a case of fungal pacemaker lead endocarditis. FE, especially in the setting of in-vivo cardiac devices, is on the rise. Read More

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http://dx.doi.org/10.7759/cureus.3553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324854PMC
November 2018
1 Read

Clinical Characteristics and Factors Associated With Mortality in First-Episode Infective Endocarditis Among Persons Who Inject Drugs.

JAMA Netw Open 2018 Nov 2;1(7):e185220. Epub 2018 Nov 2.

Infectious Diseases, St Joseph's Health Care, London Health Sciences Centre, London, Ontario, Canada.

Importance: Persons who inject drugs (PWID) represent a distinct demographic of patients with infective endocarditis. Many centers do not perform valvular surgery on these patients owing to concerns about poor outcomes. Addiction services are underused in hospitals. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2018.5220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324402PMC
November 2018
10 Reads

Clinical Features and Complications of Coxiella burnetii Infections From the French National Reference Center for Q Fever.

JAMA Netw Open 2018 Aug 3;1(4):e181580. Epub 2018 Aug 3.

Aix-Marseille University, Institut de Recherche pour le Développement (IRD), Assistance Publique Hôpitaux de Marseille (APHM), Microbes, Evolution, Phylogénie et Infections, IHU (Institut Hospitalo-Universitaire)-Méditerranée Infection, Marseille, France.

Importance: Q fever remains widespread throughout the world; the disease is serious and causes outbreaks and deaths when complications are not detected. The diagnosis of Q fever requires the demonstration of the presence of Coxiella burnetii and the identification of an organic lesion.

Objective: To describe the hitherto neglected clinical characteristics of Q fever and identifying risk factors for complications and death. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2018.1580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324270PMC
August 2018
3 Reads

Mycotic intracranial aneurysms rupture presenting as pure acute subdural hematoma in infectious endocarditis. Report of 2 cases and review of the literature.

J Clin Neurosci 2019 Jan 9. Epub 2019 Jan 9.

Department of Radiology, Assistance Publique-Hôpitaux de Paris, Bichat University Hospital, 46 rue Henri Huchard, 75018 Paris, France; INSERM U738, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, France. Electronic address:

Acute subdural hematoma (ASDH) revealing mycotic aneurysm (MA) is an exceptional occurrence. We report 2 cases of MA-related pure ASDH in the course of infective endocarditis (IE) without history of head trauma, hypertension or coagulopathy. Case 1: A 54-year-old man presented with a 10-day history of headache, fever. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.12.035DOI Listing
January 2019
1 Read

Primary Care for Persons Who Inject Drugs.

Am Fam Physician 2019 Jan;99(2):109-116

University of Maryland School of Medicine, Baltimore, MD, USA.

More than 750,000 persons in the United States inject opioids, methamphetamine, cocaine, or ketamine, and that number is increasing because of the current opioid epidemic. Persons who inject drugs (PWID) are at higher risk of infectious and noninfectious skin, pulmonary, cardiac, neurologic, and other causes of morbidity and mortality. Nonjudgmental inquiries about current drug use can uncover information about readiness for addiction treatment and identify modifiable risk factors for complications of injection drug use. Read More

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January 2019
10 Reads

[One year of infectious diseases in review].

Authors:
Olivier Clerc

Rev Med Suisse 2019 Jan;15(N° 632-633):62-64

Service de médecine interne et des maladies infectieuses, Hôpital Pourtalès, 2000 Neuchâtel.

New data were published regarding fœtal damage of Zika virus infection, and its sexual transmission. An outbreak of Ebola virus disease in the Democratic Republic of the Congo emphasizes the importance of vaccine development. In Switzerland, hospitals in the Canton of Bern were affected by a large outbreak of vancomycin-resistant enterococci. Read More

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January 2019
2 Reads

Ehlers-Danlos syndrome with infective endocarditis: A case report with literature review.

IDCases 2019 29;15:e00484. Epub 2018 Dec 29.

Department of Pulmonary and Critical Care Medicine, University of Tennessee Graduate School of Medicine, Knoxville, USA.

We report a patient with Ehlers-Danlos syndrome and mitral valve infective endocarditis. The case was complicated due to multiorgan involvement and initially diagnosed as hand-foot-and-mouth disease. The patient was transferred to our hospital with cerebral septic emboli and bilateral lower extremity emboli requiring early surgery. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22142509183022
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http://dx.doi.org/10.1016/j.idcr.2018.e00484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322054PMC
December 2018
8 Reads

The Early Diagnosis of Endophthalmitis Due to Group B Streptococcus Infective Endocarditis and Its Clinical Course: A Case Report and Literature Review.

Intern Med 2019 Jan 10. Epub 2019 Jan 10.

Division of Cardiovascular Medicine, Department of Internal Medicine, Jichi Medical University School of Medicine, Japan.

A 68-year-old Japanese man was admitted to our hospital with right eye pain, a sudden worsening of his eyesight, and a fever. He was diagnosed with endogenous bacterial endophthalmitis due to infectious endocarditis (IE) of Group B Streptococcus (GBS) on the day of admission. He recovered systemically, but his right eye became phthisical only with the administration of antibiotics. Read More

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http://dx.doi.org/10.2169/internalmedicine.2232-18DOI Listing
January 2019
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Intracranial Hemorrhaging following Cardiobacterium hominis Endocarditis.

Intern Med 2019 Jan 10. Epub 2019 Jan 10.

Emergency Medicine, Hino Municipal Hospital, Japan.

Acute infectious endocarditis (IE) is a complex disease that presents as a serious clinical condition associated with a high mortality rate, especially due to intracranial hemorrhaging (ICH). The most common causative organism is Staphylococcus aureus. We herein report a patient with ICH following subacute IE with a positive blood culture for Cardiobacterium hominis. Read More

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https://www.jstage.jst.go.jp/article/internalmedicine/advpub
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http://dx.doi.org/10.2169/internalmedicine.2111-18DOI Listing
January 2019
6 Reads

Prosthetic valve endocarditis caused by multidrug-resistant in a patient with myelodysplasia syndrome: A case report and literature review.

Curr Med Mycol 2018 Sep;4(3):23-27

Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Background And Purpose: endocarditis is an infrequent disease with a high mortality rate, which commonly occurs in immunosuppressed patients with cardiac valve replacement. We reported a 70-year-old woman diagnosed with prosthetic valve endocarditis (PVE). This study also involved a review of all published cases of PVE from 1970. Read More

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http://dx.doi.org/10.18502/cmm.4.3.171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315203PMC
September 2018
1 Read

Risk-benefit assessment of systematic thoracoabdominopelvic CT scan in infective endocarditis.

Clin Infect Dis 2019 Jan 7. Epub 2019 Jan 7.

Department of Infectious Disease, CHU Hôtel-Dieu, Nantes, France.

Background: In the management of Infective Endocarditis (IE), the presence of extracardiac complications has an influence on both diagnosis and treatment. Current guidelines suggest that systematic thoraco-abdomino-pelvic CT scan (TAP-CT) may be helpful. Our objective was to describe how systematic TAP-CT affects the diagnosis and the management of IE. Read More

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http://dx.doi.org/10.1093/cid/ciz014DOI Listing
January 2019
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Case report: Staphylococcus aureus endocarditis in 2 premature newborns.

Medicine (Baltimore) 2019 Jan;98(1):e13549

Neonatal Intensive Care Unit, Department of Pediatric Medicine, CHU de Saint-Etienne.

Rationale: Neonatal infectious endocarditis (IE) in a healthy heart is rare. The infectious agents most frequently found in newborns are Staphylococcus aureus and fungi. Infection at the site of central intravenous catheter is generally thought to be the cause of this pathology. Read More

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http://dx.doi.org/10.1097/MD.0000000000013549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344129PMC
January 2019
5 Reads

Torsades de Pointes in Intravenous Drug Abuse-Associated Infective Endocarditis.

Heart Surg Forum 2018 Dec 19;21(6):E507-E512. Epub 2018 Dec 19.

Northeast Ohio Medical University, Rootstown, OH, USA.

Intravenous drug abuse rates in the United States have increased exponentially in recent years. Ohio is one of 5 states with the highest age-adjusted drug overdose death rates, with drug overdose causing 39.1 of every 100,000 deaths. Read More

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http://dx.doi.org/10.1532/hsf.2167DOI Listing
December 2018
3 Reads

Imaging of cerebrovascular complications of infection.

Quant Imaging Med Surg 2018 Nov;8(10):1039-1051

Department of Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China.

Cerebrovascular complications may occur in infectious diseases in the setting of infective endocarditis, central nervous system (CNS) infections, systemic bacteremia and sepsis. Cerebrovascular complications of infections include vasculitis, mycotic aneurysms, and thrombophlebitis. Infectious vasculitis of the CNS may cause cerebral hemorrhage, infarction or ischemia. Read More

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http://qims.amegroups.com/article/view/22608/21889
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http://dx.doi.org/10.21037/qims.2018.11.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288057PMC
November 2018
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Probiotic supplements might not be universally-effective and safe: A review.

Biomed Pharmacother 2018 Dec 28;111:537-547. Epub 2018 Dec 28.

Department of Animal Science and Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 05029, Republic of Korea. Electronic address:

Last few decades have witnessed the unprecedented growth in the application of probiotics for promoting the general gut health as well as their inception as biotherapeutics to alleviate certain clinical disorders related to dysbiosis. While numerous studies have substantiated the health-restoring potentials for a restricted group of microbial species, the marketed extrapolation of a similar probiotic label to a large number of partially characterized microbial formulations seems biased. In particular, the individuals under neonatal stages and/or those with some clinical conditions including malignancies, leaky gut, diabetes mellitus, and post-organ transplant convalescence likely fail to reap the benefits of probiotics. Read More

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http://dx.doi.org/10.1016/j.biopha.2018.12.104DOI Listing
December 2018
1 Read