5,221 results match your criteria Infection[Journal]


Suboptimal performance of APRI and FIB-4 in ruling out significant fibrosis and confirming cirrhosis in HIV/HCV co-infected and HCV mono-infected patients.

Infection 2018 Dec 5. Epub 2018 Dec 5.

Department of Sciences for Health Promotion "G. D'Alessandro", University of Palermo, Palermo, Italy.

Purpose: We aimed to assess the diagnostic reliability of two indirect biomarkers, APRI and FIB-4, for the staging of liver fibrosis using transient elastography (TE) as reference standard, among HIV/HCV co-infected and HCV mono-infected patients.

Methods: This is an observational, retrospective study on subjects who had access to the RESIST HCV from October 2013 to December 2016, a regional network encompassing 22 hospitals and academic centers throughout Sicily. Sensitivity, specificity and diagnostic accuracy of indirect biomarkers for liver stiffness measurement (LSM) < 9. Read More

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December 2018

Challenges in HSV encephalitis: normocellular CSF, unremarkable CCT, and atypical MRI findings.

Infection 2018 Dec 1. Epub 2018 Dec 1.

Department of Neurology, Klinikum der Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.

Purpose: Herpes simplex virus (HSV) encephalitis continues to be the most common form of sporadic lethal encephalitis worldwide. The wide spectrum of clinical presentations and laboratory findings often poses a diagnostic challenge for physicians which might delay administration of life-saving therapy with acyclovir. Atypical presentations of HSV encephalitis have become increasingly prevalent with better diagnostic techniques and have not been well studied. Read More

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December 2018
2 Reads

Correction to: A review on anti-adhesion therapies of bacterial diseases.

Infection 2018 Nov 30. Epub 2018 Nov 30.

Department of Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

The presentation of Table  was incorrect. The corrected table is given below. Read More

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November 2018

Cystic echinococcosis in the thigh: a case report.

Infection 2018 Dec 3. Epub 2018 Dec 3.

Department of Internal Medicine II, Innsbruck Medical University, Anichstraße 35, 6020, Innsbruck, Austria.

Intramuscular cystic echinococcosis is a very rare occurrence. Herein we report a case of a 37-year-old patient who presented with progressive swelling of his left thigh. Ultrasound evaluation showed a multicystic, encapsulated lesion (16 × 3. Read More

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December 2018

Correlation between Streptococcus bovis bacteremia and density of cows in Galicia, northwest of Spain.

Infection 2018 Nov 29. Epub 2018 Nov 29.

Infectious Diseases Unit, Hospital Universitario Lucus Augusti, Lugo, Spain.

Background: There are few data on the epidemiology of infections caused by Streptococcus bovis (Sb). Some studies suggest that both residence in rural areas and contact with livestock could be potential risk factors.

Methods: We performed a retrospective study for the period 2005-2016 of all cases of bacteremia caused by Sb in Galicia (a region in the northwest of Spain). Read More

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November 2018
2 Reads

Daptomycin vs. glycopeptides in the treatment of febrile neutropenia: results of the Izmir matched cohort study.

Infection 2018 Nov 29. Epub 2018 Nov 29.

Department of Infectious Diseases and Clinical Microbiology, Ege University Faculty of Medicine, Izmir, Turkey.

Purpose: In this multicentre, retrospective, matched cohort study we aimed to evaluate the outcomes of neutropenic fever cases that were treated with daptomycin or a glycopeptide (vancomycin or teicoplanin).

Methods: Data and outcomes of adult (aged > 18-years old) patients with neutropenic fever [(1) without clinical and radiological evidence of pneumonia, (2) who were treated with daptomycin or a glycopeptide (teicoplanin or vancomycin) for any reason and for at least 72 h] were extracted from the hospital databases. Matching was performed with all of the three following criteria: (1) underlying disease, (2) reason for starting daptomycin or glycopeptide (microbiologic evidence vs. Read More

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November 2018

Dialysis drains as a possible source for carbapenem-resistant pathogens causing an ICU outbreak.

Infection 2018 Nov 21. Epub 2018 Nov 21.

Klinik für Anästhesiologie and Intensivmedizin, Universität Duisburg-Essen and Universitätsklinikum Essen, Essen, Germany.

Objective Design: We describe a case series of patients colonized with KPC-producing Enterobacteriaceae related to dialysis drains at patient's bedside.

Setting: The study was set at the intensive care unit (ICU) of a tertiary referral hospital.

Patients: In March 2016, we discovered four ICU patients to be colonized with KPC-producing Enterobacteriaceae in routine screening. Read More

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November 2018
2 Reads

Correction to: A retrospective analysis of weight changes in HIV-positive patients switching from a tenofovir disoproxil fumarate (TDF)- to a tenofovir alafenamide fumarate (TAF)-containing treatment regimen in one German university hospital in 2015-2017.

Infection 2018 Nov 19. Epub 2018 Nov 19.

Sektion Klinische Infektiologie, Medizinische Klinik und Poliklinik IV, Klinikum der Universität, Ludwig-Maximilians-Universität München, Pettenkoferstrasse 8a, 80336, Munich, Germany.

The original version of this article unfortunately contained mistakes. Read More

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November 2018

Nitroxoline: an option for the treatment of urinary tract infection with multi-resistant uropathogenic bacteria.

Infection 2018 Nov 17. Epub 2018 Nov 17.

Department of Pneumology, Theresienkrankenhaus, Bassermannstr. 1, 68165, Mannheim, Germany.

The number of multi-resistant uropathogens is increasing. A multi-morbid patient developed a symptomatic urinary tract infection with two multi-resistant bacteria, namely Klebsiella pneumoniae and Proteus mirabilis. Nitroxoline was the only drug active against both uropathogens. Read More

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November 2018
5 Reads

Outpatient parenteral antimicrobial therapy and antibiotic stewardship: opponents or teammates?

Infection 2018 Nov 15. Epub 2018 Nov 15.

Department of Infection Control and Epidemiology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Purpose: This narrative review aims to describe barriers of outpatient parenteral antimicrobial therapy at home (OPAT), potentially compromising general standards of antibiotic stewardship (ABS) and facilitators of OPAT for ABS.

Methods: After a literature review, five authors determined the barriers and facilitators to discuss in this review.

Results: Sixty-six publications were included in the narrative review and seven barriers and five facilitators are discussed in this article. Read More

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November 2018
3 Reads

Vaccine strain Listeria monocytogenes bacteremia occurring 31 months after immunization.

Infection 2018 Nov 14. Epub 2018 Nov 14.

Section of Infectious Diseases, Department of Internal Medicine, University of Oklahoma Health Sciences Center, 800 Stanton L. Young Blvd, Suite 7300, Oklahoma City, OK, 73104, USA.

Background: Listeria monocytogenes is a food-borne, facultative intracellular bacterium that causes severe diseases such as sepsis and meningoencephalitis in immunocompromised hosts. Because it stimulates robust T-lymphocyte-mediated responses, attenuated L. monocytogenes are candidate vaccine vectors for tumor immunotherapy. Read More

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November 2018
2 Reads

Daptomycin-associated myopathy induced by concomitant administration of mirabegron.

Infection 2018 Nov 14. Epub 2018 Nov 14.

Division of Infection Control and Prevention, Osaka University Hospital, 2-15 Yamadaoka, Suita, Osaka, 565-0871, Japan.

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November 2018

Treatment of a broncho-esophageal fistula complicated by severe ARDS.

Infection 2018 Nov 11. Epub 2018 Nov 11.

Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, University of Freiburg, Freiburg, Germany.

Introduction: Broncho-esophageal fistula formation is a rare complication of tuberculosis, most often seen in immunocompromised patients.

Methods And Results: In this paper, we report the case of a young non-immunocompromised refugee from Somalia diagnosed with open pulmonary tuberculosis complicated by extensive osseous involvement and a broncho-esophageal fistula with consecutive aspiration of gastric contents. The patient rapidly developed a severe acute respiratory distress syndrome (ARDS) requiring venovenous extracorporeal membrane oxygenation (ECMO) therapy for nearly 2 months. Read More

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November 2018
13 Reads

Antiretroviral treatment indications and adherence to the German-Austrian treatment initiation guidelines in the German ClinSurv HIV Cohort between 1999 and 2016.

Infection 2018 Nov 9. Epub 2018 Nov 9.

Department I for Internal Medicine, University Hospital of Cologne, Cologne, Germany.

Purpose: The aim of the study was to assess guideline adherence to combined antiretroviral therapy (ART) in the German ClinSurv HIV Cohort and the real-life impact of the Strategic Timing of Antiretroviral Therapy (START) study, to identify patients not treated as recommended by new guidelines.

Methods: We used data from the multicenter ClinSurv cohort of the Robert-Koch-Institute (RKI) between 1999 and 2016. Inclusion criteria were people living with HIV/AIDS, ≥ 18 years of age and cART naïve at the first visit (FV). Read More

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November 2018
6 Reads

Actinomyces spp. bloodstream and deep vein thrombus infections in people who inject drugs.

Infection 2018 Nov 8. Epub 2018 Nov 8.

Dorevitch Pathology, 18 Banksia St, Heidelberg, Melbourne, 3084, Australia.

Introduction: Actinomyces spp. cause several well-described syndromes including cervicofacial and pelvic infections. Actinomyces spp. Read More

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November 2018
1 Read

Risk factors for recurrent percutaneous nephrostomy catheter-related infections.

Infection 2018 Nov 7. Epub 2018 Nov 7.

Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1460, Houston, TX, 77030, USA.

Purpose: Percutaneous nephrostomy (PCN) catheters are mainly indicated for urinary tract obstructions. Unfortunately, the rate for infection and recurrence remains elevated. Our objective was to identify the risk factors leading to recurrent PCN-related infections (PCNI) in cancer patients. Read More

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November 2018
6 Reads

Neglected tropical diseases in Europe: rare diseases and orphan drugs?

Infection 2018 Nov 2. Epub 2018 Nov 2.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Negrar-Verona, Italy.

Neglected tropical diseases are becoming more and more frequent in Europe due to the increasing immigration from endemic areas. Nonetheless specific treatments are scarcely available in many European countries, since they are neither officially licensed nor marketed. Only a few referral health centres can afford to access drugs for NTDs due to complex bureaucracy and high cost, importing or providing them via the WHO. Read More

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November 2018

Current opinions regarding the management of pyogenic flexor tenosynovitis: a survey of Pulvertaft Hand Trauma Symposium attendees.

Infection 2018 Nov 1. Epub 2018 Nov 1.

The Pulvertaft Hand Surgery Unit, Royal Derby Hospital, Derby, DE22 3NE, UK.

Purpose: Pyogenic flexor tenosynovitis (PFT) is recognized as a severe infection of the hand with potentially disastrous outcomes. The mainstay of treatment has been emergent surgical washout. Recent evidence suggests potential for conservative management with a combination of intravenous antibiotics, elevation and splinting. Read More

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November 2018
4 Reads

Urinary schistosomiasis in migrant population: a case series from a single centre in southern Italy.

Infection 2018 Oct 30. Epub 2018 Oct 30.

Unit of Infectious Diseases and Centre for Migration and Health, ARNAS, Ospedale Civico Benfratelli, Piazza Nicola Leotta 4, 90127, Palermo, Italy.

Purpose: To understand the frequency of urinary schistosomiasis, in migrants in clinical follow-up at the infectious disease outpatient clinic of ARNAS Civico Hospital in Palermo Italy, to raise awareness on this neglected tropical disease.

Methods: A retrospective analysis of migrant patients in clinical care in our centre during the triennium 2015-2017.

Results: 2639 migrants have been in clinical care during the triennium 2015-2017, 72% are male and 28% are female. Read More

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October 2018
1 Read

Risk factors of bloodstream infections in recipients after liver transplantation: a meta-analysis.

Infection 2018 Oct 28. Epub 2018 Oct 28.

School of Public Health and Management, Chongqing Medical University, No.1 Yixueyuan Road, Yuzhong District, Chongqing, 400016, China.

Purpose: Bloodstream infection (BSI) is an important cause of adverse outcomes for recipients with liver transplantation (LT). This meta-analysis aimed to identify risk factors associated with post-LT BSI.

Methods: Relevant studies published up to June 2017 were searched from seven electronic databases. Read More

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October 2018
5 Reads

Late reactivation of hepatitis B virus after rituximab-containing chemotherapy for mantle cell lymphoma: a case report.

Infection 2018 Oct 27. Epub 2018 Oct 27.

Internal Medicine, Gastroenterology and Hepatology Unit, Fondazione Agostino Gemelli Hospital, Catholic University, Rome, Italy.

Background: Hepatitis B virus (HBV) reactivation is commonly observed in HBsAg-positive hematologic patients undergoing immunosuppressive chemotherapy. Recent guidelines recommend antiviral prophylaxis to be continued for up to 12 months after the discontinuation of the anticancer regimen.

Case Presentation: We report a case of a patient who underwent antiviral prophylaxis for 26 months after the discontinuation of a rituximab-containing chemotherapy regimen for a lymphoma and was admitted in the infectious diseases department with a 3-day history of jaundice, itching, and dark urine. Read More

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October 2018
4 Reads

Fluorescent in situ hybridization can be used as a complementary assay for the diagnosis of Tropheryma whipplei infection.

Infection 2018 Oct 27. Epub 2018 Oct 27.

Aix Marseille Université, IRD, APHM, MEPHI, IHU-Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005, Marseille, France.

Background: Immunohistochemistry and Periodic acid-Schiff (PAS) staining have been routinely used for the diagnosis of Whipple's disease (WD). However, these methods present limitations. As a result, the last years, Fluorescence in situ hybridization (FISH) has been increasingly used as a complementary tool for the diagnosis of WD from various tissue samples. Read More

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October 2018
4 Reads

Hemodialysis vascular graft as a focus of persistent Q fever.

Infection 2018 Dec 27;46(6):881-884. Epub 2018 Oct 27.

Department of Nephrology, AP-HM Hôpital de la Conception, Aix-Marseille University, 147 Boulevard Baille, 13005, Marseille, France.

Vascular access infection is a frequent complication in hemodialysis patients. We report the second case worldwide of a prosthetic hemodialysis vascular graft infection by Coxiella burnetii, with intense hypermetabolism on PET-CT, Q fever serology consistent with persistent infection, and positive C. burnetii DNA in the blood and removed vascular graft. Read More

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December 2018
3 Reads

17th-century sculptural representation of leprosy in Perugia's Cathedral.

Infection 2018 Dec 23;46(6):893-895. Epub 2018 Oct 23.

University of the Arts, Central Saint Martins, Granary Building, 1 Granary Square, King's Cross, London, N1C 4AA, UK.

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December 2018
1 Read

Chronic meningococcemia: a report of 26 cases and literature review.

Infection 2018 Oct 19. Epub 2018 Oct 19.

Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, 2, Rue Henri Le Guilloux, 35033, Rennes Cedex 9, France.

Chronic meningococcemia is defined by blood culture(s) positive for Neisseria meningitidis, symptoms duration > 7 days, and neither meningitis nor shock on admission. This series of 26 consecutive cases illustrates that this is a rare disease (< 5% of meningococcemia, < 0.05 cases per 100,000 inhabitants per year), mostly affecting young adults, males, with no predisposing condition. Read More

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October 2018
5 Reads

Acinetobacter baumannii meningitis in children: a case series and literature review.

Infection 2018 Oct 16. Epub 2018 Oct 16.

Department of Pediatric Intensive Care Unit, The Children's Hospital, Zhejiang University School of Medicine, 3333 Bingsheng Road, Hangzhou, 310003, China.

Introduction: The incidence of Acinetobacter baumannii meningitis, which typically occurs after neurosurgery, has increased in recent years. Pediatric Acinetobacter baumannii meningitis due to the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains has important clinical significance.

Methodology: We retrospectively reviewed the clinical course and outcome of nine cases of meningitis due to Acinetobacter baumannii in children and reviewed the relevant literature. Read More

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October 2018
14 Reads

Use of steroids for abdominal tuberculosis: a systematic review and meta-analysis.

Infection 2018 Oct 15. Epub 2018 Oct 15.

Department of Gastroenterology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Background: The role of adjunctive steroids in abdominal tuberculosis is unclear.

Objective: To evaluate effect of adjunctive use of steroids for abdominal tuberculosis in reducing/preventing complications.

Methods: We searched electronic databases (Medline, Embase, CENTRAL, Scopus, Web of Science, CINAHL) from inception to 25th June 2018 using the terms "abdominal tuberculosis" OR "intestinal tuberculosis" OR "peritoneal tuberculosis" OR "tuberculous peritonitis" AND steroids OR methylprednisolone OR prednisolone. Read More

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October 2018
3 Reads
2.618 Impact Factor

Resignment: Infection is grateful to Prof. Alexander von Graevenitz.

Infection 2018 Dec;46(6):749-750

Sektion Klinische Infektiologie, Klinik und Poliklinik IV, Klinikum der Universität München, Pettenkoferstr. 8a, 80336, Munich, Germany.

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December 2018

A phase III, open-label, single-arm, study to evaluate the safety and immunogenicity of a trivalent, surface antigen inactivated subunit influenza virus vaccine produced in mammalian cell culture (Optaflu®) in healthy adults.

Infection 2018 Oct 8. Epub 2018 Oct 8.

Department of Tropical Medicine and Infectious Diseases, University of Rostock, Ernst-Heydemann Strasse 6, 18057, Rostock, Germany.

Vaccination is an essential tool in reducing the impact of seasonal influenza infections. The viral strains responsible for seasonal outbreaks vary annually, and preventive vaccines have to be adapted accordingly. The aim of this study was to evaluate the safety, clinical tolerability and the antibody response to each of the three influenza vaccine antigens after vaccination with a cell-derived, trivalent, surface antigen, inactivated influenza vaccine (TIVc), as measured by single radial haemolysis (SRH) or haemagglutination inhibition (HI) assay in accordance with European Union licensing guidelines in place for years 2013/2014. Read More

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October 2018

F-FDG PET/CT monitoring of non-tuberculous mycobacterial infection in a child with interleukin-12 receptor β-1 deficiency.

Infection 2018 Oct 8. Epub 2018 Oct 8.

General Paediatrics and Infectious and Tropical Diseases Department, Hospital La Paz-IdiPAZ, Paseo de la Castellana 261, 28046, Madrid, Spain.

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October 2018
2 Reads

Inhaled corticosteroids and risk of upper respiratory tract infection in patients with asthma: a meta-analysis.

Infection 2018 Oct 8. Epub 2018 Oct 8.

Respiratory Diseases Laboratory, Chengdu Second People's Hospital, No. 10, Qingyun South Street, Chengdu, 610017, China.

Background: Recent studies have suggested a possible association between respiratory infection and the use of inhaled corticosteroids (ICS). We aimed to ascertain the risk of upper respiratory tract infection (URTI) with long-term inhaled corticosteroid use among patients with asthma.

Methods: Through a comprehensive literature search of PubMed, Cochrane Library, EMBASE, and Google Scholar from inception to May 2018, we included randomized controlled trials of any ICS vs. Read More

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October 2018
1 Read

Diagnosis of nontuberculous mycobacterial disease in the era of surveillance chest CT scans.

Infection 2018 Dec 8;46(6):861-865. Epub 2018 Oct 8.

Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Miami, Miami, FL, USA.

The radiologic surveillance of smokers with low-dose CT scan has led to a significant surge of radiologic incidental findings, including the detection of early stages of pulmonary infections including nontuberculous mycobacteria (NTM). This causes a state of overdiagnosis and potential overtreatment of NTM lung disease. Here we propose a new approach to NTM pulmonary disease in the era of increased CT scanning. Read More

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December 2018
1 Read

Non-granulomatous cerebellar infection by Acanthamoeba spp. in an immunocompetent host.

Infection 2018 Dec 4;46(6):885-889. Epub 2018 Oct 4.

Hospital Department of Specialized and Internal Medicine, Infectious Diseases Unit, University Hospital of Siena, Siena, Italy.

Acanthamoeba spp. is a free-living amoeba, frequently involved in keratitis by contact lens in immunocompetent hosts. Anecdotal reports associate Acanthamoeba spp. Read More

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December 2018
20 Reads

A review on anti-adhesion therapies of bacterial diseases.

Infection 2018 Oct 1. Epub 2018 Oct 1.

Department of Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Infections caused by bacteria are a foremost cause of morbidity and mortality in the world. The common strategy of treating bacterial infections is by local or systemic administration of antimicrobial agents. Currently, the increasing antibiotic resistance is a serious and global problem. Read More

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October 2018

A retrospective analysis of weight changes in HIV-positive patients switching from a tenofovir disoproxil fumarate (TDF)- to a tenofovir alafenamide fumarate (TAF)-containing treatment regimen in one German university hospital in 2015-2017.

Infection 2018 Sep 29. Epub 2018 Sep 29.

Sektion Klinische Infektiologie, Medizinische Klinik und Poliklinik IV, Klinikum der Universität, Ludwig-Maximilians-Universität München, Pettenkoferstrasse 8a, 80336, Munich, Germany.

Purpose: To determine whether changing from a tenofovir disoproxil fumarate (TDF)- to a tenofovir alafenamide fumarate (TAF)-containing regimen is correlated with weight changes in a human immunodeficiency virus (HIV)-positive adult cohort.

Methods: Retrospective analysis was conducted of data gathered from routine care in a university hospital in Munich, Germany, between July 2015 and June 2017. Data from patients' charts were extracted and a two-step approach was applied. Read More

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September 2018
1 Read

Serological biomarkers of candidemia: a retrospective evaluation of three assays.

Infection 2018 Sep 27. Epub 2018 Sep 27.

Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Medizinische Fakultät, LMU München, Munich, Germany.

Purpose: Serologic testing allows for rapid detection of candidemia. More data are needed for the Virion\Serion ELISA antigen test (Ag), Hemkit Candida IHA antibody test (Ab), and Wako β-1,3-D-glucan assay (BDG).

Methods: Tests were performed on serum samples from 120 cases of culture-confirmed candidemia and 44 Candida-negative controls. Read More

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September 2018
6 Reads

Tuberculosis-associated hemophagocytic lymphohistiocytosis with subsequent unmasking cryptococcal immune reconstitution inflammatory syndrome (IRIS) in an HIV-negative man.

Infection 2018 Sep 26. Epub 2018 Sep 26.

Department of Tropical Medicine and Infectious Diseases, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany.

A 22-year-old HIV-negative man from Ghana was diagnosed with severe hemophagocytic lymphohistiocytosis (HLH) induced by multiorgan tuberculosis with peritoneal, hepatic, pericardial, myocardial, pleural, pulmonary, and bone manifestation. His body mass index was 12.9 m/kg. Read More

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September 2018
1 Read

Management of hepatitis C virus infection in patients with chronic kidney disease: position statement of the joint committee of Italian association for the study of the liver (AISF), Italian society of internal medicine (SIMI), Italian society of infectious and tropical disease (SIMIT) and Italian society of nephrology (SIN).

Infection 2018 Sep 25. Epub 2018 Sep 25.

Department of Experimental and Clinical Medicine, Interdepartmental Hepatology Center MaSVE, University of Florence, Florence, Italy.

Hepatitis C virus (HCV) infection is now considered a systemic disease due to the occurrence of extra-hepatic manifestations. Among these, the renal involvement is frequent. HCV infection, in fact, is strongly associated with proteinuria and chronic kidney disease (CKD) and negatively affects the prognosis of renal patients. Read More

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September 2018
2 Reads

Efficacy of lamivudine prophylaxis in preventing hepatitis B virus reactivation in patients with resolved infection undergoing allogeneic SCT and receiving rituximab.

Infection 2018 Sep 19. Epub 2018 Sep 19.

Division of Infectious Diseases, Department of Health Sciences, University of Genoa, Genoa, Italy.

Purpose: Hepatitis B virus (HBV) reactivation during immunosuppressive therapy is common in patients with hematological malignancies, even in case of resolved infection. Prophylaxis of HBV reactivation is universally recommended in stem cell transplant (SCT) recipients and patients treated with anti-CD20 agents (i.e. Read More

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September 2018
3 Reads

'Lost in Nasal Space': Staphylococcus aureus sepsis associated with Nasal Handkerchief Packing.

Infection 2018 Sep 18. Epub 2018 Sep 18.

Department I of Internal Medicine, Intensive Care Unit, University Hospital of Cologne, Cologne, Germany.

Introduction: Staphylococcus aureus frequently causes infections in outpatient and hospital settings and can present as a highly variable entity. Typical manifestations are endocarditis, osteoarticular infections or infection of implanted prostheses, intravascular devices or foreign bodies. A thorough diagnostic evaluation with early focus identification is mandatory to improve patient outcome. Read More

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September 2018
1 Read

Severe pulmonary haemorrhage syndrome in leptospirosis in a returning traveller.

Infection 2018 Sep 18. Epub 2018 Sep 18.

Department of Gastroenterology, Hepatology and Infectious Diseases, Düsseldorf University Hospital, Heinrich Heine University, Düsseldorf, Germany.

Clinical presentation of leptospirosis ranges from asymptomatic infection to fulminant, life-threatening disease. Pulmonary involvement in terms of severe pulmonary haemorrhage syndrome (SPHS) has recently become a more frequently reported facet of leptospirosis and correlates with high mortality rates. It has not yet been described in returning German travellers. Read More

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September 2018
7 Reads

Health-related quality of life in patients with alveolar echinococcosis: a cross-sectional study.

Infection 2018 Sep 17. Epub 2018 Sep 17.

Department of Internal Medicine III, Ulm University Hospital, Albert-Einstein-Allee 23, 89081, Ulm, Germany.

Purpose: The Alveolar echinococcosis (AE) is a rare zoonosis caused by the parasite Echinococcus multilocularis. To date, nothing is known about the health-related quality of life (HRQoL) in patients with AE. The aim of the study was to evaluate the HRQoL in patients with AE in comparison of the healthy population. Read More

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September 2018
15 Reads

Essentials in Candida bloodstream infection.

Infection 2018 Sep 14. Epub 2018 Sep 14.

Department I for Internal Medicine, ECMM Excellence Centre of Medical Mycology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany.

Aims: Due to the increase of severely immunocompromised patients, of invasive procedures including central intravascular catheters, and of the use of broad-spectrum antibiotics, the incidence of Candida bloodstream infections has risen intensely in the last decades. Candida bloodstream infection is a serious disease with high mortality. Optimized diagnostic and therapeutic management can improve outcome. Read More

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September 2018

Correction to: Mucormycosis in hospitalized patients at a tertiary care center in Lebanon: a case series.

Infection 2018 Sep 14. Epub 2018 Sep 14.

Division of Infectious Diseases, American University of Beirut Medical Center, Riad El Solh, PO Box 11-0236, Beirut, 1107 2020, Lebanon.

The spelling of the name "Ali Bazarbachi" was incorrect. Read More

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September 2018
1 Read

Nachruf Prof. Dr. med. Georg Peters.

Authors:

Infection 2018 Sep 14. Epub 2018 Sep 14.

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September 2018

Increasing incidence of candidaemia and shifting epidemiology in favor of Candida non-albicans in a 9-year period (2009-2017) in a university Greek hospital.

Infection 2018 Sep 8. Epub 2018 Sep 8.

Department of Microbiology, School of Medicine, University of Patras, Rion, 26504, Patras, Greece.

Purpose: The aim of the present study was to analyze candidaemia's epidemiology (incidence, species distribution, and susceptibility rates) and antifungal consumption during a 9-year period.

Methods: All candidaemias recorded at The University General Hospital of Patras, Greece, between 2009 and 2017 were included. Candida isolates were identified using the germ tube test, API 20C AUX System, and/or Vitek-2 YST card. Read More

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September 2018

Comparison of patient characteristics, clinical management, infectious specialist consultation, and outcome in men and women with methicillin-sensitive Staphylococcus aureus bacteremia: a propensity-score adjusted retrospective study.

Infection 2018 Dec 7;46(6):837-845. Epub 2018 Sep 7.

Division of Infectious Diseases, Department of Medicine, Inflammation Center, Helsinki University Central Hospital, Aurora Hospital, University of Helsinki, Nordenskiöldinkatu 26, Building 3, P.O. Box 348, 00029 HUS, Helsinki, Finland.

Background: Sex-related treatment inequalities are suggested to explain outcome differences between men and women in Staphylococcus aureus bacteremia (SAB). We compared patient characteristics, clinical management, infectious specialist consultation (ISC) and outcome in men and women with SAB.

Methods: Multicenter retrospective study of methicillin-sensitive (MS-) SAB patients categorized according to sex and ISC consultation provided within 7 days of diagnosis. Read More

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December 2018

Interest of immunodeficiency screening in adult after admission in medical intensive care unit for severe infection, a retrospective and a prospective study: the Intensive Care Unit and Primary and Secondary Immunodeficiency (ICUSPID) study.

Infection 2018 Sep 7. Epub 2018 Sep 7.

Internal Medicine Department, Saint-Joseph Hospital, Boulevard de Louvain, 13008, Marseille, France.

Background: Primary immunodeficiency (PID) in adults is rare and mostly revealed by infections.

Material And Methods: Adults without predisposing factors who were admitted to an intensive care unit (ICU) for infection were screened for PID.

Results: Six PID cases were diagnosed, mostly revealed by encapsulated bacterial infections. Read More

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September 2018
1 Read