5,241 results match your criteria Infection[Journal]


Liver fibrosis is associated with cognitive impairment in people living with HIV.

Infection 2019 Feb 19. Epub 2019 Feb 19.

Institute of Clinical Infectious Diseases, Catholic University of Sacred Heart, Rome, Italy.

Purpose: Our aim was to better explore the association between liver fibrosis (LF) and neurocognitive impairment (NCI) in people living with HIV (PLWH).

Methods: We performed a cross-sectional cohort study by consecutively enrolling PLWH at two clinical centers. All subjects underwent a comprehensive neuropsychological battery; NCI was defined as having a pathological performance (1. Read More

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http://link.springer.com/10.1007/s15010-019-01284-8
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http://dx.doi.org/10.1007/s15010-019-01284-8DOI Listing
February 2019
3 Reads

Focal spleen lesions in visceral leishmaniasis, a neglected manifestation of a neglected disease: report of three cases and systematic review of literature.

Infection 2019 Feb 15. Epub 2019 Feb 15.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Background: The Mediterranean area is endemic for the zoonotic form of visceral leishmaniasis (VL) caused by Leishmania infantum, a species which has been recently associated with unexpected epidemiological and clinical features.

Method: We report the result of a systematic review of the literature on VL unusually presenting with spleen focal lesions, including three previously unpublished cases.

Results: A total of 28 cases of VL with multiple spleen focal lesions were retrieved. Read More

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http://dx.doi.org/10.1007/s15010-019-01279-5DOI Listing
February 2019
1 Read

Acute epididymo-orchitis due to Salmonella Typhi in a young man from Bangladesh.

Infection 2019 Feb 15. Epub 2019 Feb 15.

Department of Infectious and Tropical Diseases, Spedali Civili, Piazzale Spedali Civili, 1, 25123, Brescia, Italy.

S. typhi infection rarely involves the genitourinary system. We report the first described case of acute epididymo-orchitis due to S. Read More

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http://dx.doi.org/10.1007/s15010-019-01280-yDOI Listing
February 2019

Derivation of a quick Pitt bacteremia score to predict mortality in patients with Gram-negative bloodstream infection.

Infection 2019 Feb 8. Epub 2019 Feb 8.

Department of Medicine, Palmetto Health University of South Carolina Medical Group, Columbia, SC, USA.

Purpose: This retrospective cohort study derived a "quick" version of the Pitt bacteremia score (qPitt) using binary variables in patients with Gram-negative bloodstream infections (BSI). The qPitt discrimination was then compared to quick sepsis-related organ failure assessment (qSOFA) and systemic inflammatory response syndrome (SIRS).

Methods: Hospitalized adults with Gram-negative BSI at Palmetto Health hospitals in Columbia, SC, USA from 2010 to 2013 were identified. Read More

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http://dx.doi.org/10.1007/s15010-019-01277-7DOI Listing
February 2019
1 Read

Antagonistic effect between tigecycline and meropenem: successful management of KPC-producing Klebsiella pneumoniae infection.

Infection 2019 Feb 7. Epub 2019 Feb 7.

Center of Clinical Laboratory, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Introduction: A woman infected by carbapenem-resistant Klebsiella pneumoniae is reported in this study.

Case Report: Tigecycline and meropenem combination was used, and indeed, in vitro checkerboard synergy test confirmed the antagonism between the two antibiotics. Thus, meropenem was ceased and single high-dose tigecycline was successful against the infection. Read More

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http://dx.doi.org/10.1007/s15010-019-01274-wDOI Listing
February 2019

Invasive fungal disease is associated with chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplant: a single center, retrospective study.

Infection 2019 Feb 7. Epub 2019 Feb 7.

Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Background: Invasive fungal disease (IFD) and graft-versus-host disease (GVHD) are major causes of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, the impacts of IFD on chronic GVHD remain unknown.

Methods: We conducted a retrospective study of 510 patients with hematologic malignancy undergoing allo-HSCT to explore the effects of IFD on chronic GVHD. Read More

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http://dx.doi.org/10.1007/s15010-018-01265-3DOI Listing
February 2019
1 Read

First reported human case of meningitis by Staphylococcus condimenti.

Infection 2019 Feb 7. Epub 2019 Feb 7.

S.C.D.U. Medicina Interna I, A.O.U. Maggiore Della Carità, Università del Piemonte Orientale, via Mazzini 18, 28100, Novara, Italy.

Staphylococcus condimenti (S. condimenti) is a coagulase-negative bacterium, generally regarded as not pathogenic. Indeed, S. Read More

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http://dx.doi.org/10.1007/s15010-018-01266-2DOI Listing
February 2019
1 Read

In vitro activity of voriconazole and amphotericin B against Candida albicans, Candida krusei, and Cryptococcus neoformans in human cerebrospinal fluid.

Infection 2019 Feb 6. Epub 2019 Feb 6.

Department of Clinical Pharmacology, Vienna University Hospital, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Purpose: Fungal central nervous system (CNS) infections show a high mortality rate and only a few antifungal agents are available to treat these infections. We hypothesize that the different biochemical properties of human cerebrospinal fluid (CSF) compared to the standard growth medium lead to the altered activity of antifungal agents in CSF. We investigated the in vitro activity of two of these agents, i. Read More

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http://dx.doi.org/10.1007/s15010-019-01275-9DOI Listing
February 2019

HBsAg-negative/anti-HBc-positive patients treated with rituximab: prophylaxis or monitoring to prevent hepatitis B reactivation?

Infection 2019 Jan 28. Epub 2019 Jan 28.

Department I of Internal Medicine, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.

Rituximab (RTX) has been classified as a drug associated with a high risk for hepatitis B virus (HBV) reactivation in HbsAg-negative/anti-HBc-positive patients. However, data on frequency of HBV reactivation are limited especially for RTX monotherapy. Several new recommendations for screening, monitoring and prophylactic antiviral treatment have been published recently. Read More

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http://dx.doi.org/10.1007/s15010-019-01271-zDOI Listing
January 2019

M. pneumoniae and C. pneumoniae are no relevant pathogens in critically ill patients with hospital-acquired respiratory tract infections.

Infection 2019 Jan 28. Epub 2019 Jan 28.

Institute for Infectious Diseases and Infection Control, Jena University Hospital, Am Klinikum 1, 07747, Jena, Germany.

Purpose: To assess the incidence of Mycoplasma pneumoniae and Chlamydia pneumoniae in the pathogenesis of hospital-acquired respiratory tract infections (RTIs) in critically ill patients.

Methods: This is a retrospective cohort study of all ICU-patients ≥ 18 years with RTI who underwent conventional culture techniques and PCR testing for both M. pneumoniae and C. Read More

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http://dx.doi.org/10.1007/s15010-019-01273-xDOI Listing
January 2019
1 Read

Sepsis: a frequent topic in a new Editorial Section in INFECTION.

Authors:
J R Bogner

Infection 2019 Feb;47(1):1-2

Klinik und Poliklinik IV, Sektion Klinische Infektiologie, Klinikum der Universität München, Pettenkoferstr. 8a, 80336, Munich, Germany.

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http://dx.doi.org/10.1007/s15010-019-01272-yDOI Listing
February 2019

The diagnosis and treatment of urogenital schistosomiasis in Italy in a retrospective cohort of immigrants from Sub-Saharan Africa.

Infection 2019 Jan 21. Epub 2019 Jan 21.

Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.

Objectives: To evaluate ultrasound and praziquantel to, respectively, assess and reduce urogenital schistosomiasis (UGS)-associated morbidity in migrants from Sub-Saharan Africa (SSA).

Methods: Migrants from SSA with UGS attending three Italian centres for tropical diseases during 2011-2016 were retrospectively enrolled. Data on clinical symptoms, routine laboratory, parasitological tests, and ultrasound reported as per the WHO-Niamey protocol were collected at baseline and at available follow-up visits after treatment with praziquantel 40 mg/kg/day for 3 days. Read More

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http://dx.doi.org/10.1007/s15010-019-01270-0DOI Listing
January 2019
2 Reads
2.618 Impact Factor

Post-malaria neurological syndrome: a rare neurological complication of malaria.

Infection 2019 Jan 21. Epub 2019 Jan 21.

Department of Medicine, Division of Infectious Disease, SUNY Upstate Medical Center, Syracuse, NY, USA.

Background: Post-malaria neurological syndrome (PMNS) is a rare self-limiting neurological complication that can occur after recovery from malaria, usually severe falciparum malaria. It is characterized by a myriad of neuropsychiatric manifestations including mild neurological deficit to severe encephalopathy. PMNS was first described in 1996 and since then there have been 48 cases reported in the English literature. Read More

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http://dx.doi.org/10.1007/s15010-019-01267-9DOI Listing
January 2019

Tularemia: an experience of 13 cases including a rare myocarditis in a referral center in Eastern Switzerland (Central Europe) and a review of the literature.

Infection 2019 Jan 17. Epub 2019 Jan 17.

Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St. Gallen, Rorschacher Strasse 95, 9007, St. Gallen, Switzerland.

Background: Tularemia, a zoonotic disease caused by Francisella tularensis, can cause a broad spectrum of disease in humans including six major clinical presentations: the ulceroglandular, glandular, oculoglandular, oropharyngeal, typhoidal and pneumonic form. The epidemiology and ecology and thus transmission of tularemia are complex, depending on conditions unique to specific locations.

Case Series And Methods: Thirteen cases with different forms of the disease and one very rare case of a myocarditis are reported, discussed, and reviewed within the scope of current literature. Read More

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http://dx.doi.org/10.1007/s15010-019-01269-7DOI Listing
January 2019
1 Read

Cerebrospinal fluid compartmentalization of HIV-1 and correlation with plasma viral load and blood-brain barrier damage.

Infection 2019 Jan 16. Epub 2019 Jan 16.

Clinic of Infectious Diseases, University of Bari "Aldo Moro", Piazza G. Cesare, 11, 70124, Bari, Italy.

Purpose: We aimed to evaluate HIV-1 compartmentalization between the cerebrospinal fluid (CSF) and plasma and investigate as to which extent HIV-1 strains in CSF differ from those in blood and whether a correlation with either plasma viral load (pVL) or an altered blood-brain barrier (BBB) does exist.

Study Design: We retrospectively evaluated paired CSF/blood samples collected from 86 HIV+ patients. HIV-RNA quantification, pol (PR/RT), and V3 sequencing were performed. Read More

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http://dx.doi.org/10.1007/s15010-019-01268-8DOI Listing
January 2019

Analysis of acute respiratory infections due to influenza virus A, B and RSV during an influenza epidemic 2018.

Infection 2019 Jan 16. Epub 2019 Jan 16.

Kliniken für Pneumologie und Infektiologie, EVK Herne und Augusta-Kranken-Anstalt Bochum, Thoraxzentrum Ruhrgebiet, Bergstrasse 26, 44791, Bochum, Germany.

Purpose: We studied the incidence, morbidity and mortality of all patients presenting in our teaching hospital with proven influenza virus and/or respiratory syncytial virus (RSV) infection during the influenza epidemic season 2018 which was characterized by a predominant incidence of influenza virus B type B of the Yamagata line.

Methods: In the fall of 2017, specific precaution measures in addition to standard measures were implemented, including standardized testing for influenza virus A,B and RSV by multiplex PCR of pharyngeal swabsData from all consecutive patients were analyzed retrospectively.

Results: Overall 651 patients were examined for the presence of influenza virus and RSV; 214 patients had influenza virus A (n = 36), B (n = 152), and/or RSV (n = 30), including four patients with dual infection. Read More

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http://link.springer.com/10.1007/s15010-018-1262-x
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http://dx.doi.org/10.1007/s15010-018-1262-xDOI Listing
January 2019
12 Reads

Correction to: Mucormycosis in hospitalized patients at a tertiary care center in Lebanon: a case series.

Infection 2019 Jan 7. Epub 2019 Jan 7.

Division of Infectious Diseases, American University of Beirut Medical Center, Riad El Solh, PO Box 11‑0236, Beirut, 1107 2020, Lebanon.

Unfortunately, the original version of this article contains mistakes. The names "Jean El-Cheikh" and Aline El Zakhem were spelled incorrectly. Read More

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http://dx.doi.org/10.1007/s15010-018-1259-5DOI Listing
January 2019
2.618 Impact Factor

Management of early- and late-onset sepsis: results from a survey in 80 German NICUs.

Infection 2019 Jan 3. Epub 2019 Jan 3.

Department of Pediatric Hematology and Oncology, Children's Hospital Medical Center, University Hospital of Saarland, Gebäude 9, Kirrberger Straße, 66421, Homburg/Saar, Germany.

Purpose: The management of early- (EOS) and late-onset sepsis (LOS) and neonatal intensive care units (NICUs) has not been extensively evaluated.

Methods: 231 highly specialized level 1 and level 2 NICUs in Germany were asked to participate in an internet-based survey.

Results: The final analysis of anonymized datasets from 80 NICUs (response rate 34. Read More

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http://dx.doi.org/10.1007/s15010-018-1263-9DOI Listing
January 2019

Enterococcal bacteremia in febrile neutropenic children and adolescents with underlying malignancies, and clinical impact of vancomycin resistance.

Infection 2018 Dec 19. Epub 2018 Dec 19.

Department of Pediatrics, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.

Purpose: Enterococci are a common cause of bacteremia in immunocompromised patients. Although the increase of vancomycin-resistant enterococci (VRE) makes appropriate antibiotic therapy difficult, clinical characteristics of enterococcal bacteremia and the impact of VRE infection on outcomes have rarely been reported in immunocompromised children.

Methods: We enrolled children and adolescents (< 19 years of age) with underlying malignancies who were diagnosed with enterococcal bacteremia during febrile neutropenia between 2010 and 2017. Read More

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http://dx.doi.org/10.1007/s15010-018-1260-zDOI Listing
December 2018

Lung transplantation in two cystic fibrosis patients infected with previously pandrug-resistant Burkholderia cepacia complex treated with ceftazidime-avibactam.

Infection 2018 Dec 19. Epub 2018 Dec 19.

Infectious Diseases Department, Hospital Universitari Vall d'Hebron, P° Vall d'Hebron 119-129, 08035, Barcelona, Spain.

We describe two cystic fibrosis patients infected with pandrug-resistant Burkholderia cepacia complex, with the exception of ceftazidime-avibactam, who received prophylaxis with this antibiotic during lung transplantation. Although both patients had a post-operative relapse of respiratory infection, one with positive blood cultures, ceftazidime-avibactam treatment yielded a favourable outcome. 12 months after transplantation, one patient presented an excellent clinical outcome. Read More

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http://link.springer.com/10.1007/s15010-018-1261-y
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http://dx.doi.org/10.1007/s15010-018-1261-yDOI Listing
December 2018
3 Reads

Suboptimal performance of APRI and FIB-4 in ruling out significant fibrosis and confirming cirrhosis in HIV/HCV co-infected and HCV mono-infected patients.

Infection 2018 Dec 5. Epub 2018 Dec 5.

Department of Sciences for Health Promotion "G. D'Alessandro", University of Palermo, Palermo, Italy.

Purpose: We aimed to assess the diagnostic reliability of two indirect biomarkers, APRI and FIB-4, for the staging of liver fibrosis using transient elastography (TE) as reference standard, among HIV/HCV co-infected and HCV mono-infected patients.

Methods: This is an observational, retrospective study on subjects who had access to the RESIST HCV from October 2013 to December 2016, a regional network encompassing 22 hospitals and academic centers throughout Sicily. Sensitivity, specificity and diagnostic accuracy of indirect biomarkers for liver stiffness measurement (LSM) < 9. Read More

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http://dx.doi.org/10.1007/s15010-018-1258-6DOI Listing
December 2018
1 Read

Challenges in HSV encephalitis: normocellular CSF, unremarkable CCT, and atypical MRI findings.

Infection 2018 Dec 1. Epub 2018 Dec 1.

Department of Neurology, Klinikum der Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.

Purpose: Herpes simplex virus (HSV) encephalitis continues to be the most common form of sporadic lethal encephalitis worldwide. The wide spectrum of clinical presentations and laboratory findings often poses a diagnostic challenge for physicians which might delay administration of life-saving therapy with acyclovir. Atypical presentations of HSV encephalitis have become increasingly prevalent with better diagnostic techniques and have not been well studied. Read More

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http://link.springer.com/10.1007/s15010-018-1257-7
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http://dx.doi.org/10.1007/s15010-018-1257-7DOI Listing
December 2018
9 Reads

Correction to: A review on anti-adhesion therapies of bacterial diseases.

Infection 2019 Feb;47(1):25-26

Department of Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

The presentation of Table  was incorrect. The corrected table is given below. Read More

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http://dx.doi.org/10.1007/s15010-018-1240-3DOI Listing
February 2019

Cystic echinococcosis in the thigh: a case report.

Infection 2018 Dec 3. Epub 2018 Dec 3.

Department of Internal Medicine II, Innsbruck Medical University, Anichstraße 35, 6020, Innsbruck, Austria.

Intramuscular cystic echinococcosis is a very rare occurrence. Herein we report a case of a 37-year-old patient who presented with progressive swelling of his left thigh. Ultrasound evaluation showed a multicystic, encapsulated lesion (16 × 3. Read More

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http://dx.doi.org/10.1007/s15010-018-1255-9DOI Listing
December 2018

Correlation between Streptococcus bovis bacteremia and density of cows in Galicia, northwest of Spain.

Infection 2018 Nov 29. Epub 2018 Nov 29.

Infectious Diseases Unit, Hospital Universitario Lucus Augusti, Lugo, Spain.

Background: There are few data on the epidemiology of infections caused by Streptococcus bovis (Sb). Some studies suggest that both residence in rural areas and contact with livestock could be potential risk factors.

Methods: We performed a retrospective study for the period 2005-2016 of all cases of bacteremia caused by Sb in Galicia (a region in the northwest of Spain). Read More

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http://dx.doi.org/10.1007/s15010-018-1254-xDOI Listing
November 2018
2 Reads

Daptomycin vs. glycopeptides in the treatment of febrile neutropenia: results of the Izmir matched cohort study.

Infection 2018 Nov 29. Epub 2018 Nov 29.

Department of Infectious Diseases and Clinical Microbiology, Ege University Faculty of Medicine, Izmir, Turkey.

Purpose: In this multicentre, retrospective, matched cohort study we aimed to evaluate the outcomes of neutropenic fever cases that were treated with daptomycin or a glycopeptide (vancomycin or teicoplanin).

Methods: Data and outcomes of adult (aged > 18-years old) patients with neutropenic fever [(1) without clinical and radiological evidence of pneumonia, (2) who were treated with daptomycin or a glycopeptide (teicoplanin or vancomycin) for any reason and for at least 72 h] were extracted from the hospital databases. Matching was performed with all of the three following criteria: (1) underlying disease, (2) reason for starting daptomycin or glycopeptide (microbiologic evidence vs. Read More

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http://dx.doi.org/10.1007/s15010-018-1256-8DOI Listing
November 2018

Dialysis drains as a possible source for carbapenem-resistant pathogens causing an ICU outbreak.

Infection 2018 Nov 21. Epub 2018 Nov 21.

Klinik für Anästhesiologie and Intensivmedizin, Universität Duisburg-Essen and Universitätsklinikum Essen, Essen, Germany.

Objective Design: We describe a case series of patients colonized with KPC-producing Enterobacteriaceae related to dialysis drains at patient's bedside.

Setting: The study was set at the intensive care unit (ICU) of a tertiary referral hospital.

Patients: In March 2016, we discovered four ICU patients to be colonized with KPC-producing Enterobacteriaceae in routine screening. Read More

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http://dx.doi.org/10.1007/s15010-018-1239-9DOI Listing
November 2018
8 Reads

Correction to: A retrospective analysis of weight changes in HIV-positive patients switching from a tenofovir disoproxil fumarate (TDF)- to a tenofovir alafenamide fumarate (TAF)-containing treatment regimen in one German university hospital in 2015-2017.

Infection 2019 Feb;47(1):103-104

Sektion Klinische Infektiologie, Medizinische Klinik und Poliklinik IV, Klinikum der Universität, Ludwig-Maximilians-Universität München, Pettenkoferstrasse 8a, 80336, Munich, Germany.

The original version of this article unfortunately contained mistakes. Read More

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http://dx.doi.org/10.1007/s15010-018-1251-0DOI Listing
February 2019
2 Reads

Nitroxoline: an option for the treatment of urinary tract infection with multi-resistant uropathogenic bacteria.

Infection 2018 Nov 17. Epub 2018 Nov 17.

Department of Pneumology, Theresienkrankenhaus, Bassermannstr. 1, 68165, Mannheim, Germany.

The number of multi-resistant uropathogens is increasing. A multi-morbid patient developed a symptomatic urinary tract infection with two multi-resistant bacteria, namely Klebsiella pneumoniae and Proteus mirabilis. Nitroxoline was the only drug active against both uropathogens. Read More

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http://link.springer.com/10.1007/s15010-018-1253-y
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http://dx.doi.org/10.1007/s15010-018-1253-yDOI Listing
November 2018
6 Reads

Outpatient parenteral antimicrobial therapy and antibiotic stewardship: opponents or teammates?

Infection 2018 Nov 15. Epub 2018 Nov 15.

Department of Infection Control and Epidemiology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Purpose: This narrative review aims to describe barriers of outpatient parenteral antimicrobial therapy at home (OPAT), potentially compromising general standards of antibiotic stewardship (ABS) and facilitators of OPAT for ABS.

Methods: After a literature review, five authors determined the barriers and facilitators to discuss in this review.

Results: Sixty-six publications were included in the narrative review and seven barriers and five facilitators are discussed in this article. Read More

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http://link.springer.com/10.1007/s15010-018-1250-1
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http://dx.doi.org/10.1007/s15010-018-1250-1DOI Listing
November 2018
7 Reads

Vaccine strain Listeria monocytogenes bacteremia occurring 31 months after immunization.

Infection 2018 Nov 14. Epub 2018 Nov 14.

Section of Infectious Diseases, Department of Internal Medicine, University of Oklahoma Health Sciences Center, 800 Stanton L. Young Blvd, Suite 7300, Oklahoma City, OK, 73104, USA.

Background: Listeria monocytogenes is a food-borne, facultative intracellular bacterium that causes severe diseases such as sepsis and meningoencephalitis in immunocompromised hosts. Because it stimulates robust T-lymphocyte-mediated responses, attenuated L. monocytogenes are candidate vaccine vectors for tumor immunotherapy. Read More

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http://link.springer.com/10.1007/s15010-018-1249-7
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http://dx.doi.org/10.1007/s15010-018-1249-7DOI Listing
November 2018
6 Reads

Daptomycin-associated myopathy induced by concomitant administration of mirabegron.

Infection 2018 Nov 14. Epub 2018 Nov 14.

Division of Infection Control and Prevention, Osaka University Hospital, 2-15 Yamadaoka, Suita, Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1007/s15010-018-1252-zDOI Listing
November 2018

Treatment of a broncho-esophageal fistula complicated by severe ARDS.

Infection 2018 Nov 11. Epub 2018 Nov 11.

Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, University of Freiburg, Freiburg, Germany.

Introduction: Broncho-esophageal fistula formation is a rare complication of tuberculosis, most often seen in immunocompromised patients.

Methods And Results: In this paper, we report the case of a young non-immunocompromised refugee from Somalia diagnosed with open pulmonary tuberculosis complicated by extensive osseous involvement and a broncho-esophageal fistula with consecutive aspiration of gastric contents. The patient rapidly developed a severe acute respiratory distress syndrome (ARDS) requiring venovenous extracorporeal membrane oxygenation (ECMO) therapy for nearly 2 months. Read More

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http://link.springer.com/10.1007/s15010-018-1247-9
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http://dx.doi.org/10.1007/s15010-018-1247-9DOI Listing
November 2018
20 Reads

Antiretroviral treatment indications and adherence to the German-Austrian treatment initiation guidelines in the German ClinSurv HIV Cohort between 1999 and 2016.

Infection 2018 Nov 9. Epub 2018 Nov 9.

Department I for Internal Medicine, University Hospital of Cologne, Cologne, Germany.

Purpose: The aim of the study was to assess guideline adherence to combined antiretroviral therapy (ART) in the German ClinSurv HIV Cohort and the real-life impact of the Strategic Timing of Antiretroviral Therapy (START) study, to identify patients not treated as recommended by new guidelines.

Methods: We used data from the multicenter ClinSurv cohort of the Robert-Koch-Institute (RKI) between 1999 and 2016. Inclusion criteria were people living with HIV/AIDS, ≥ 18 years of age and cART naïve at the first visit (FV). Read More

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http://link.springer.com/10.1007/s15010-018-1248-8
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http://dx.doi.org/10.1007/s15010-018-1248-8DOI Listing
November 2018
9 Reads

Actinomyces spp. bloodstream and deep vein thrombus infections in people who inject drugs.

Infection 2018 Nov 8. Epub 2018 Nov 8.

Dorevitch Pathology, 18 Banksia St, Heidelberg, Melbourne, 3084, Australia.

Introduction: Actinomyces spp. cause several well-described syndromes including cervicofacial and pelvic infections. Actinomyces spp. Read More

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http://dx.doi.org/10.1007/s15010-018-1246-xDOI Listing
November 2018
1 Read

Risk factors for recurrent percutaneous nephrostomy catheter-related infections.

Infection 2018 Nov 7. Epub 2018 Nov 7.

Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1460, Houston, TX, 77030, USA.

Purpose: Percutaneous nephrostomy (PCN) catheters are mainly indicated for urinary tract obstructions. Unfortunately, the rate for infection and recurrence remains elevated. Our objective was to identify the risk factors leading to recurrent PCN-related infections (PCNI) in cancer patients. Read More

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http://link.springer.com/10.1007/s15010-018-1245-y
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http://dx.doi.org/10.1007/s15010-018-1245-yDOI Listing
November 2018
9 Reads

Neglected tropical diseases in Europe: rare diseases and orphan drugs?

Infection 2019 Feb 2;47(1):3-5. Epub 2018 Nov 2.

Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Negrar-Verona, Italy.

Neglected tropical diseases are becoming more and more frequent in Europe due to the increasing immigration from endemic areas. Nonetheless specific treatments are scarcely available in many European countries, since they are neither officially licensed nor marketed. Only a few referral health centres can afford to access drugs for NTDs due to complex bureaucracy and high cost, importing or providing them via the WHO. Read More

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http://dx.doi.org/10.1007/s15010-018-1241-2DOI Listing
February 2019

Current opinions regarding the management of pyogenic flexor tenosynovitis: a survey of Pulvertaft Hand Trauma Symposium attendees.

Infection 2018 Nov 1. Epub 2018 Nov 1.

The Pulvertaft Hand Surgery Unit, Royal Derby Hospital, Derby, DE22 3NE, UK.

Purpose: Pyogenic flexor tenosynovitis (PFT) is recognized as a severe infection of the hand with potentially disastrous outcomes. The mainstay of treatment has been emergent surgical washout. Recent evidence suggests potential for conservative management with a combination of intravenous antibiotics, elevation and splinting. Read More

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http://link.springer.com/10.1007/s15010-018-1236-z
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http://dx.doi.org/10.1007/s15010-018-1236-zDOI Listing
November 2018
8 Reads

Urinary schistosomiasis in migrant population: a case series from a single centre in southern Italy.

Infection 2018 Oct 30. Epub 2018 Oct 30.

Unit of Infectious Diseases and Centre for Migration and Health, ARNAS, Ospedale Civico Benfratelli, Piazza Nicola Leotta 4, 90127, Palermo, Italy.

Purpose: To understand the frequency of urinary schistosomiasis, in migrants in clinical follow-up at the infectious disease outpatient clinic of ARNAS Civico Hospital in Palermo Italy, to raise awareness on this neglected tropical disease.

Methods: A retrospective analysis of migrant patients in clinical care in our centre during the triennium 2015-2017.

Results: 2639 migrants have been in clinical care during the triennium 2015-2017, 72% are male and 28% are female. Read More

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http://dx.doi.org/10.1007/s15010-018-1244-zDOI Listing
October 2018
1 Read

Risk factors of bloodstream infections in recipients after liver transplantation: a meta-analysis.

Infection 2019 Feb 28;47(1):77-85. Epub 2018 Oct 28.

School of Public Health and Management, Chongqing Medical University, No.1 Yixueyuan Road, Yuzhong District, Chongqing, 400016, China.

Purpose: Bloodstream infection (BSI) is an important cause of adverse outcomes for recipients with liver transplantation (LT). This meta-analysis aimed to identify risk factors associated with post-LT BSI.

Methods: Relevant studies published up to June 2017 were searched from seven electronic databases. Read More

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http://link.springer.com/10.1007/s15010-018-1230-5
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http://dx.doi.org/10.1007/s15010-018-1230-5DOI Listing
February 2019
10 Reads

Late reactivation of hepatitis B virus after rituximab-containing chemotherapy for mantle cell lymphoma: a case report.

Infection 2018 Oct 27. Epub 2018 Oct 27.

Internal Medicine, Gastroenterology and Hepatology Unit, Fondazione Agostino Gemelli Hospital, Catholic University, Rome, Italy.

Background: Hepatitis B virus (HBV) reactivation is commonly observed in HBsAg-positive hematologic patients undergoing immunosuppressive chemotherapy. Recent guidelines recommend antiviral prophylaxis to be continued for up to 12 months after the discontinuation of the anticancer regimen.

Case Presentation: We report a case of a patient who underwent antiviral prophylaxis for 26 months after the discontinuation of a rituximab-containing chemotherapy regimen for a lymphoma and was admitted in the infectious diseases department with a 3-day history of jaundice, itching, and dark urine. Read More

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http://link.springer.com/10.1007/s15010-018-1242-1
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http://dx.doi.org/10.1007/s15010-018-1242-1DOI Listing
October 2018
4 Reads

Fluorescent in situ hybridization can be used as a complementary assay for the diagnosis of Tropheryma whipplei infection.

Infection 2018 Oct 27. Epub 2018 Oct 27.

Aix Marseille Université, IRD, APHM, MEPHI, IHU-Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005, Marseille, France.

Background: Immunohistochemistry and Periodic acid-Schiff (PAS) staining have been routinely used for the diagnosis of Whipple's disease (WD). However, these methods present limitations. As a result, the last years, Fluorescence in situ hybridization (FISH) has been increasingly used as a complementary tool for the diagnosis of WD from various tissue samples. Read More

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http://link.springer.com/10.1007/s15010-018-1243-0
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http://dx.doi.org/10.1007/s15010-018-1243-0DOI Listing
October 2018
5 Reads

Hemodialysis vascular graft as a focus of persistent Q fever.

Infection 2018 Dec 27;46(6):881-884. Epub 2018 Oct 27.

Department of Nephrology, AP-HM Hôpital de la Conception, Aix-Marseille University, 147 Boulevard Baille, 13005, Marseille, France.

Vascular access infection is a frequent complication in hemodialysis patients. We report the second case worldwide of a prosthetic hemodialysis vascular graft infection by Coxiella burnetii, with intense hypermetabolism on PET-CT, Q fever serology consistent with persistent infection, and positive C. burnetii DNA in the blood and removed vascular graft. Read More

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http://link.springer.com/10.1007/s15010-018-1206-5
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http://dx.doi.org/10.1007/s15010-018-1206-5DOI Listing
December 2018
3 Reads

17th-century sculptural representation of leprosy in Perugia's Cathedral.

Infection 2018 Dec 23;46(6):893-895. Epub 2018 Oct 23.

University of the Arts, Central Saint Martins, Granary Building, 1 Granary Square, King's Cross, London, N1C 4AA, UK.

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http://dx.doi.org/10.1007/s15010-018-1237-yDOI Listing
December 2018
1 Read

Chronic meningococcemia: a report of 26 cases and literature review.

Infection 2018 Oct 19. Epub 2018 Oct 19.

Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, 2, Rue Henri Le Guilloux, 35033, Rennes Cedex 9, France.

Chronic meningococcemia is defined by blood culture(s) positive for Neisseria meningitidis, symptoms duration > 7 days, and neither meningitis nor shock on admission. This series of 26 consecutive cases illustrates that this is a rare disease (< 5% of meningococcemia, < 0.05 cases per 100,000 inhabitants per year), mostly affecting young adults, males, with no predisposing condition. Read More

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http://link.springer.com/10.1007/s15010-018-1238-x
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http://dx.doi.org/10.1007/s15010-018-1238-xDOI Listing
October 2018
11 Reads

Acinetobacter baumannii meningitis in children: a case series and literature review.

Infection 2018 Oct 16. Epub 2018 Oct 16.

Department of Pediatric Intensive Care Unit, The Children's Hospital, Zhejiang University School of Medicine, 3333 Bingsheng Road, Hangzhou, 310003, China.

Introduction: The incidence of Acinetobacter baumannii meningitis, which typically occurs after neurosurgery, has increased in recent years. Pediatric Acinetobacter baumannii meningitis due to the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains has important clinical significance.

Methodology: We retrospectively reviewed the clinical course and outcome of nine cases of meningitis due to Acinetobacter baumannii in children and reviewed the relevant literature. Read More

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http://link.springer.com/10.1007/s15010-018-1234-1
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http://dx.doi.org/10.1007/s15010-018-1234-1DOI Listing
October 2018
21 Reads

Use of steroids for abdominal tuberculosis: a systematic review and meta-analysis.

Infection 2018 Oct 15. Epub 2018 Oct 15.

Department of Gastroenterology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Background: The role of adjunctive steroids in abdominal tuberculosis is unclear.

Objective: To evaluate effect of adjunctive use of steroids for abdominal tuberculosis in reducing/preventing complications.

Methods: We searched electronic databases (Medline, Embase, CENTRAL, Scopus, Web of Science, CINAHL) from inception to 25th June 2018 using the terms "abdominal tuberculosis" OR "intestinal tuberculosis" OR "peritoneal tuberculosis" OR "tuberculous peritonitis" AND steroids OR methylprednisolone OR prednisolone. Read More

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http://link.springer.com/10.1007/s15010-018-1235-0
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http://dx.doi.org/10.1007/s15010-018-1235-0DOI Listing
October 2018
8 Reads
2.618 Impact Factor

Resignment: Infection is grateful to Prof. Alexander von Graevenitz.

Infection 2018 Dec;46(6):749-750

Sektion Klinische Infektiologie, Klinik und Poliklinik IV, Klinikum der Universität München, Pettenkoferstr. 8a, 80336, Munich, Germany.

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http://dx.doi.org/10.1007/s15010-018-1228-zDOI Listing
December 2018
1 Read

A phase III, open-label, single-arm, study to evaluate the safety and immunogenicity of a trivalent, surface antigen inactivated subunit influenza virus vaccine produced in mammalian cell culture (Optaflu®) in healthy adults.

Infection 2019 Feb 8;47(1):105-109. Epub 2018 Oct 8.

Department of Tropical Medicine and Infectious Diseases, University of Rostock, Ernst-Heydemann Strasse 6, 18057, Rostock, Germany.

Vaccination is an essential tool in reducing the impact of seasonal influenza infections. The viral strains responsible for seasonal outbreaks vary annually, and preventive vaccines have to be adapted accordingly. The aim of this study was to evaluate the safety, clinical tolerability and the antibody response to each of the three influenza vaccine antigens after vaccination with a cell-derived, trivalent, surface antigen, inactivated influenza vaccine (TIVc), as measured by single radial haemolysis (SRH) or haemagglutination inhibition (HI) assay in accordance with European Union licensing guidelines in place for years 2013/2014. Read More

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http://dx.doi.org/10.1007/s15010-018-1233-2DOI Listing
February 2019

F-FDG PET/CT monitoring of non-tuberculous mycobacterial infection in a child with interleukin-12 receptor β-1 deficiency.

Infection 2018 Oct 8. Epub 2018 Oct 8.

General Paediatrics and Infectious and Tropical Diseases Department, Hospital La Paz-IdiPAZ, Paseo de la Castellana 261, 28046, Madrid, Spain.

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http://link.springer.com/10.1007/s15010-018-1225-2
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http://dx.doi.org/10.1007/s15010-018-1225-2DOI Listing
October 2018
2 Reads