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    Infantile hemangiomas with conjunctival involvement: An underreported occurrence.
    Pediatr Dermatol 2017 Nov;34(6):681-685
    Department of Dermatology and Pediatrics, University of California, San Francisco, San Francisco, California.
    Background/objectives: Infantile hemangiomas (IHs) involving the conjunctiva are only anecdotally reported in the literature and little is known about their clinical course. In a retrospective case series we aimed to better delineate the clinical presentation, complications, and response to treatment of this uncommon subtype of IH. A classification of conjunctival IH is proposed. Read More

    Concurrent Sturge-Weber syndrome, facial infantile hemangioma, and cutis marmorata telangiectatica congenita.
    Cutis 2017 Oct;100(4):252-254
    Geisinger Commonwealth School of Medicine, Scranton, Pennsylvania, USA.
    We present a unique case of 3 vascular malformations-Sturge-Weber syndrome (SWS), facial infantile hemangioma (IH), and cutis marmorata telangiectatica congenita (CMTC)-with dermatologic manifestations presenting in the same patient. This case highlights the possibility of occurrence of multiple vascular malformations in the same patient; the potential role of epigenetic factors; and the importance of a multidisciplinary approach to diagnose, treat, and manage this complicated interplay of vascular abnormalities to achieve the best outcome. Read More

    Congenital capillary hemangioma arising from palpebral conjunctiva of a neonate.
    Indian J Ophthalmol 2017 Nov;65(11):1221-1223
    Department of Paediatric Surgery, Coimbatore Medical College Hospital, Coimbatore, Tamil Nadu, India.
    Capillary hemangioma is the most common benign vascular eyelid tumor in childhood. The periocular lesion appears within the first few weeks after birth and usually has superficial or deep components. Primary conjunctival capillary hemangiomas are rarely reported. Read More

    Orbital infantile hemangioma and rhabdomyosarcoma in children: differentiation using diffusion-weighted magnetic resonance imaging.
    J AAPOS 2017 Nov 4. Epub 2017 Nov 4.
    Section of Pediatric Neuroradiology, Division of Pediatric Radiology, Russel H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
    Purpose: To evaluate differences in magnetic resonance imaging (MRI) appearance between infantile hemangiomas and rhabdomyosarcomas of the orbit in pediatric patients using diffusion-weighted imaging.

    Methods: A multicenter retrospective review of MRIs of pediatric patients with infantile hemangiomas and rhabdomyosarcomas of the orbit was performed. MRI examinations from a total of 21 patients with infantile hemangiomas and 12 patients with rhabdomyosarcomas of the orbit were independently reviewed by two subspecialty board-certified neuroradiologists masked to the diagnosis. Read More

    Artesunate inhibits proliferation and invasion of mouse hemangioendothelioma cells in vitro and of tumor growth in vivo.
    Oncol Lett 2017 Nov 18;14(5):6170-6176. Epub 2017 Sep 18.
    Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Medical University, Yuzhong, Chongqing 400014, P.R. China.
    Artesunate has been demonstrated to be a novel potential antitumor agent in numerous studies. However, its efficacy in infantile hemangioma is unknown. The aim of the present study was to investigate the role of artesunate in the control of vascular tumor biological behavior and molecular mechanism using mouse hemangioendothelioma endothelial (EOMA) cells and a nude mouse model. Read More

    Distributive Shock in a Neonate with Diffuse Infantile Hepatic Hemangioma.
    J Emerg Med 2017 Oct 27. Epub 2017 Oct 27.
    Childrens Hospital of Michigan, Detroit, Michigan.
    Background: Hemangiomas are common cutaneous findings on healthy infants. These vascular malformations are generally benign, though in rare circumstances they can potentially be fatal. This is particularly true when the hemangiomas are large or numerous and occurring in visceral organs. Read More

    Etiology of pediatric acquired blepharoptosis.
    J AAPOS 2017 Nov 3. Epub 2017 Nov 3.
    Royal Victorian Eye and Ear Hospital, East Melbourne, VIC Australia; Department of Ophthalmology, University of Melbourne, Parkville, VIC Australia; Centre for Eye Research Australia, East Melbourne, VIC Australia.
    Purpose: To describe the etiology of acquired pediatric blepharoptosis in a large clinical series and to elucidate the causes of the disease.

    Methods: The medical records of all patients presenting with acquired blepharoptosis at two specialist ocular plastics practices and a pediatric ophthalmology practice during a period of up to 25 years were reviewed retrospectively and classified according to their diagnosis. Patients were grouped into children (<18 years), younger adults (18-40 years), and older adults (>40 years). Read More

    Role of imaging in the diagnosis of parotid infantile hemangiomas.
    Int J Pediatr Otorhinolaryngol 2017 Nov 4;102:61-66. Epub 2017 Sep 4.
    Vascular Anomalies Center, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA; Division of Vascular and Interventional Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:
    Objectives: To review the clinical presentation, imaging and follow-up of parotid infantile hemangiomas (IH).

    Methods: Over a 15-year period, all patients with a clinical diagnosis of parotid IH were evaluated. Imaging was available in 35. Read More

    Clinical and radiological evaluation of periocular infantile hemangioma treated with oral propranolol: a case series.
    Am J Ophthalmol 2017 Nov 2. Epub 2017 Nov 2.
    Departament of Ophthalmology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, , Universidade de Sao Paulo, Sao Paulo, BR.
    Purpose: Evaluate the efficacy of propranolol (3 mg/kg/day) in the treatment of periocular infantile hemangioma (IH) based on clinical and radiological findings.

    Design: Prospective interventional case series METHODS: Study of previously untreated infants with IH conducted at the ophthalmology outpatient service of HC-FMUSP (Brazil). The patients were submitted to a complete ophthalmological examination, grey-scale and Doppler US, and nuclear MRI. Read More

    Circular RNA profile of infantile hemangioma by microarray analysis.
    PLoS One 2017 2;12(11):e0187581. Epub 2017 Nov 2.
    Department of Burn and Plastic Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province, China.
    Background: Circular RNAs (circRNAs) are a recently identified class of noncoding RNAs that participate in several physiological processes. However, the expression of circRNAs in infantile hemangioma (IH) remains unknown.

    Methods: The profile of circRNAs was assessed by microarray in four pairs of IH and adjacent skin tissues. Read More

    NOTCH3 regulates stem-to-mural cell differentiation in infantile hemangioma.
    JCI Insight 2017 Nov 2;2(21). Epub 2017 Nov 2.
    Department of Surgery, Columbia University College of Physicians and Surgeons, New York, New York, USA.
    Infantile hemangioma (IH) is a vascular tumor that begins with rapid vascular proliferation shortly after birth, followed by vascular involution in early childhood. We have found that NOTCH3, a critical regulator of mural cell differentiation and maturation, is expressed in hemangioma stem cells (HemSCs), suggesting that NOTCH3 may function in HemSC-to-mural cell differentiation and pathological vessel stabilization. Here, we demonstrate that NOTCH3 is expressed in NG2+PDGFRβ+ perivascular HemSCs and CD31+GLUT1+ hemangioma endothelial cells (HemECs) in proliferating IHs and becomes mostly restricted to the αSMA+NG2loPDGFRβlo mural cells in involuting IHs. Read More

    Continuous delivery of propranolol from liposomes-in-microspheres significantly inhibits infantile hemangioma growth.
    Int J Nanomedicine 2017 18;12:6923-6936. Epub 2017 Sep 18.
    Department of Hemangioma and Vascular Malformation, Henan Provincial People's Hospital, Zhengzhou, People's Republic of China.
    Purpose: To reduce the adverse effects and high frequency of administration of propranolol to treat infantile hemangioma, we first utilized propranolol-loaded liposomes-in-microsphere (PLIM) as a novel topical release system to realize sustained release of propranolol.

    Methods: PLIM was developed from encapsulating propranolol-loaded liposomes (PLs) in microspheres made of poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-b-poly(lactic-co-glycolic acid) copolymers (PLGA-PEG-PLGA). The release profile of propranolol from PLIM was evaluated, and its biological activity was investigated in vitro using proliferation assays on hemangioma stem cells (HemSCs). Read More

    Long-Term Therapeutic Outcomes of Photodynamic Therapy Based or Photocoagulation Based Treatments on Retinal Capillary Hemangioma.
    Photomed Laser Surg 2017 Oct 25. Epub 2017 Oct 25.
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University , Guangzhou, China .
    Background: Retinal capillary hemangioma (RCH) is a rare and refractory eye tumor.

    Objective: The aim of this study was to investigate the therapeutic efficacy of two laser-based therapies for RCH, photodynamic therapy (PDT), and focal photocoagulation-based treatment.

    Materials And Methods: This was a retrospective study. Read More

    Optical coherence tomography angiography of circumscribed choroidal hemangioma treated with photodynamic therapy.
    Indian J Ophthalmol 2017 Oct;65(10):1049-1051
    San Paolo Ophthalmic Center, San Antonio Hospital, Padova, Italy.
    We describe features of a circumscribed choroidal hemangioma (CCH) treated with photodynamic therapy (PDT) by means of optical coherence tomography angiography (OCT-A). A 40-year-old man had a complaint of decreasing visual acuity in his left eye for 10 days. A diagnosis of CCH was confirmed by fundus examination, fluorescein angiography, and indocyanine green angiography. Read More

    [Vascular anomalies in the neonatal period].
    Cir Pediatr 2017 Jul 20;30(3):162-168. Epub 2017 Jul 20.
    Servicio de Cirugía Pediátrica. Hospital Sant Joan de Déu. Barcelona.
    Objective: Vascular anomalies in the neonatal period are a diagnostic challenge for the lack of evident signs, symptoms and follow-up, and the convenience of restricting aggressive diagnostic tests. The aim of this work is to review the characteristics of neonatal cases presented to our Vascular Anomalies Unit in the last 5 years.

    Materials And Methods: All cases of suspected vascular anomaly presented to our unit before 1 month of age between 2010 and 2015 were reviewed, diagnostic tests and treatments carried out with chronology were analyzed. Read More

    Masses of the Nose, Nasal Cavity, and Nasopharynx in Children.
    Radiographics 2017 Oct;37(6):1704-1730
    From the Department of Radiology, Nationwide Children's Hospital, 700 Children's Dr, Columbus, OH 43205 (D.P.R.); and Department of Radiology, Cincinnati Children's Hospital, Cincinnati, Ohio (E.S.O., B.L.K.).
    A wide range of masses develop in the nose, nasal cavity, and nasopharynx in children. These lesions may arise from the nasal ala or other structures of the nose, including the mucosa covering any surface of the nasal cavity, the cartilaginous or osseous portion of the nasal septum, the nasal turbinates, and the nasal bones. Lesions may also arise from the nasopharynx or adjacent structures and involve the nose by way of direct extension. Read More

    Infantile hemangioma: factors causing recurrence after propranolol treatment.
    Pediatr Res 2017 Oct 11. Epub 2017 Oct 11.
    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
    BackgroundPropranolol is the first-choice treatment for severe infantile hemangioma (IH). However, 10- 30% of lesions relapse after propranolol treatment. The mechanisms underlying IH recurrence after propranolol treatment have not been completely elucidated. Read More

    A 63-Year-Old Woman With Neurofibromatosis Type 1 and Pulmonary Hypertension With Worsening Hypoxemia.
    Chest 2017 Oct;152(4):e89-e93
    Division of Pulmonary, Critical Care, and Sleep Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA.
    Case Presentation: A 63-year-old woman with a history of neurofibromatosis type-1 (NF-1) and pulmonary arterial hypertension (PAH) thought to be secondary to the NF-1 presented with a few weeks of worsening dyspnea on exertion. She took no medications other than sildenafil for her pulmonary hypertension (PH). She denied tobacco, alcohol, and illicit or anorectic drug use. Read More

    Combined Oral and Topical Beta Blockers for the Treatment of Early Proliferative Superficial Periocular Infantile Capillary Hemangioma.
    J Pediatr Ophthalmol Strabismus 2017 Oct 9:1-6. Epub 2017 Oct 9.
    Purpose: To evaluate the safety and efficacy of combined oral and topical beta blockers for the treatment of superficial periocular infantile hemangioma at the early proliferative stage.

    Methods: This was a randomized, controlled comparison trial involving 25 patients. Patients were randomly enrolled into two groups: the topical and systemic treatment and systemic treatment only groups. Read More

    Propranolol Treatment of Vascular Anomalies Other Than Infantile Hemangioma.
    J Craniofac Surg 2017 Nov;28(8):2001-2003
    Department of Plastic and Oral Surgery Children's Hospital Boston Harvard Medical School Boston, MA.
    Background: Oral propranolol has become first-line intervention for problematic infantile hemangioma (IH) that is not amenable to topical or intralesional therapies. Consensus data supporting its efficacy for other vascular anomalies does not exist. The purpose of this study was to determine the frequency and causes of propranolol use for vascular lesions other than IH. Read More

    Nearly asymptomatic intracranial capillary hemangiomas: A case report and literature review.
    Exp Ther Med 2017 Sep 11;14(3):2007-2014. Epub 2017 Jul 11.
    Department of Neurosurgery, PLA Army General Hospital, Beijing 100700, P.R. China.
    The present study reported a nearly asymptomatic case of intracranial capillary hemangioma (ICHs), which are rare benign vascular tumors or tumor-like lesions. A 33-year-old female came to the hospital with a complaint of a slight but recurring morning headache concentrated in the left posterior occipital area. These headaches spontaneously resolved without any treatment. Read More

    PLGA nanoparticles with CD133 aptamers for targeted delivery and sustained release of propranolol to hemangioma.
    Nanomedicine (Lond) 2017 Nov 29;12(21):2611-2624. Epub 2017 Sep 29.
    Department of Vascular Surgery, Shandong Provincial Hospital affiliated to Shandong University, 324 Jingwuweiqi Road, Ji'nan 250021, China.
    Aim: To develop propranolol-loaded poly(lactic-co-glycolic acid) nanoparticle with CD133 aptamers (PPN-CD133) to treat infantile hemangioma.

    Materials & Methods: The antihemangioma activity and mechanism of PPN-CD133 were evaluated.

    Results & Conclusion: PPN-CD133 are of desired size (143. Read More

    The expression and function of miR-424 in infantile skin hemangioma and its mechanism.
    Sci Rep 2017 Sep 19;7(1):11846. Epub 2017 Sep 19.
    Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
    Infantile hemangioma is the most common benign tumor in infants. Many studies have confirmed that basic fibroblast growth factor (bFGF) and its key receptor FGFR1 are highly expressed in hemangioma. Moreover, several miRNAs can regulate angiogenesis. Read More

    Inhibition of hemangioma growth using polymer-lipid hybrid nanoparticles for delivery of rapamycin.
    Biomed Pharmacother 2017 Nov 10;95:875-884. Epub 2017 Sep 10.
    Department of Vascular Surgery, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefangdadao Road, Wuhan 430022, Hubei, China. Electronic address:
    Although infantile hemangiomas is benign, its rapid growth may induce serious complications. However, only one drug Hemangeol™ has been approved by US Food and Drug Administration (FDA) to treat infantile hemangiomas. Thus it is necessary to develop novel alternative drugs to treat infantile hemangiomas. Read More

    Exploring the association between chorangioma and infantile haemangioma in singleton and multiple pregnancies: a case-control study in a Swedish tertiary centre.
    BMJ Open 2017 Sep 3;7(9):e015539. Epub 2017 Sep 3.
    Section of Perinatal Pathology, Department of Pathology, Karolinska University Hospital Huddinge, Stockholm, Sweden.
    Objectives: Placenta or placental chorangioma could be the origin site of infantile haemangioma since they share various histochemical and genetic characteristics with placental vascular tissue. The aim of the current study was to investigate the association between chorangiomas and infantile haemangiomas in singleton and multiple pregnancies.

    Materials And Methods: An informative questionnaire enquiring about the presence or not of infantile haemangioma and including illustrative photos of haemangioma was sent to 469 (153 cases with chorangioma and 316 controls) mothers of 323 singleton (104 cases and 219 controls) and 146 multiple (49 cases and 97 controls) liveborn neonates registered in Sweden. Read More

    Treatment of Refractory Infantile Hemangiomas and Pulmonary Hypertension With Sirolimus in a Pediatric Patient.
    J Pediatr Hematol Oncol 2017 Oct;39(7):e391-e393
    Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI.
    Infantile hemangioma is a benign vascular neoplasm that spontaneously involutes over time. Management, when needed, consists of medications, laser treatment and surgical excision. We describe a 3-year-old girl who presented shortly after birth with diffuse cutaneous hemangiomas, hepatosplenomegaly with liver lesions, anemia, and acute heart failure. Read More

    Survivin: A novel marker and potential therapeutic target for human angiosarcoma.
    Cancer Sci 2017 Nov 15;108(11):2295-2305. Epub 2017 Sep 15.
    Division of Cancer Biology, National Cancer Center Research Institute, Tokyo, Japan.
    Human angiosarcoma is a rare malignant vascular tumor associated with extremely poor clinical outcome and generally arising in skin of the head and neck region. However, little is known about the molecular pathogeneses and useful immunohistochemical markers of angiosarcoma. To investigate the mechanisms of angiosarcoma progression, we collected 85 cases of human angiosarcoma specimens with clinical records and analyzed ISO-HAS-B patient-derived angiosarcoma cells. Read More

    Prevalence and pattern of lobular capillary hemangioma in Eastern Madhya Pradesh, India: A clinicopathological analysis.
    Indian J Dent Res 2017 Jul-Aug;28(4):424-428
    Department of Oral and Maxillofacial Surgery, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
    Background: Lobular capillary hemangioma is a common benign vascular tumor seen in the oral cavity. It occurs in response to various stimuli such as low-grade local irritation, traumatic insult, and hormonal factors or as a response to a wide variety of drugs.

    Materials And Methods: All patients presenting to the Department of Dentistry, Shyam Shah Medical College, Rewa, Madhya Pradesh during July 2014 to June 2016, who were diagnosed by histopathologic confirmation as oral lobular capillary hemangioma (OLCH), were evaluated for the area involved, clinicopathologic presentation, demographic features, and treatment. Read More

    Intradural-Extramedullary Capillary Hemangioma with Acute Bleeding: Case Report and Literature Review.
    World Neurosurg 2017 Aug 18. Epub 2017 Aug 18.
    Department of Neurosurgery, 12 de Octubre University Hospital, Madrid, Spain.
    Objectives: Capillary hemangiomas are benign vascular tumors. They are commonly founded in the vertebral bodies but very seldom in the spinal cord. The most common symptom at onset is long-lasting axial pain without neurologic deficit. Read More

    Use of the Hemangioma Severity Scale to facilitate treatment decisions for infantile hemangiomas.
    J Am Acad Dermatol 2017 Nov 14;77(5):868-873. Epub 2017 Aug 14.
    Department of Dermatology, Hecovan Expertise-Center for Hemangioma and Vascular Malformations, Radboud University Medical Center, Nijmegen, The Netherlands.
    Background: The Hemangioma Severity Scale (HSS) assesses the severity of an infantile hemangioma (IH).

    Objective: First, to compare HSS scores between patients with IH for whom propranolol treatment was indicated at their first visit and those who were not treated. Second, to assess suitable cutoff values for the need for propranolol treatment. Read More

    Unexpected Effect of Propranolol and Prednisolone on Infantile Facial Rhabdomyosarcoma.
    J Pediatr Hematol Oncol 2017 Nov;39(8):e460-e462
    *Sushma Koirala Memorial Hospital, Sakhu-Kathmandu, Nepal †Division of Plastic Surgery, San Diego School of Medicine, University of California, Frankfurt am Main ‡Institute for Dermatopathology, Friedrichshafen, Germany.
    A 14-month-old Nepalese infant had developed a rapidly growing facial tumor originating from a dark spot on her upper eyelid. A cavernous hemangioma was suspected and treated with high doses of propranolol and prednisolone. Remission was dramatic. Read More

    Anastomosing haemangioma of liver: A case report.
    Mol Clin Oncol 2017 Sep 24;7(3):507-509. Epub 2017 Jul 24.
    Department of Radiology, Shanghai Jing'an District Centre Hospital, Shanghai 200040, P.R. China.
    Anastomosing haemangioma (AH) is a recently described, unusual variant of capillary hemangioma that appears to be unique to the genitourinary system, with a particular proclivity for the kidney. AH is a subtype of capillary haemangioma, which is rarely encountered in clinical practice, particularly in the liver. We herein present the case of a 57-year-old woman with an incidental finding on magnetic resonance imaging of a local lesion in the liver, sized 3. Read More

    Study of Cognitive Function in Children Treated with Propranolol for Infantile Hemangioma.
    Pediatr Dermatol 2017 Sep 14;34(5):554-558. Epub 2017 Aug 14.
    Department of Dermatology, Hospital del Niño Jesús, Madrid, Spain.
    Background: Oral propranolol is considered the first choice for the treatment of infantile hemangiomas (IHs). There is a concern that administering propranolol in newborns and infants could induce adverse effects in learning and memory processes in the long term. The purpose of this study was to assess cognitive and memory functions in children who had been treated with propranolol for IH during their infancy. Read More

    MicroRNA-137 and microRNA-195* inhibit vasculogenesis in brain arteriovenous malformations.
    Ann Neurol 2017 Sep 8;82(3):371-384. Epub 2017 Sep 8.
    Neuroscience and Neuroengineering Research Center, Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
    Objective: Brain arteriovenous malformations (AVMs) are the most common cause of nontraumatic intracerebral hemorrhage in young adults. The genesis of brain AVM remains enigmatic. We investigated microRNA (miRNA) expression and its contribution to the pathogenesis of brain AVMs. Read More

    Different Clinical Features of Acral Abortive Hemangiomas.
    Case Rep Dermatol Med 2017 12;2017:2897617. Epub 2017 Jul 12.
    Department of Pediatric Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.
    Some infantile hemangiomas called in literature "minimal or arrested growth hemangiomas" or "abortive hemangiomas" are present at birth and have a proliferative component equaling less than 25% of its total surface area. Often, they are mistaken for vascular malformation. We present five patients (three girls and two boys) with abortive hemangiomas diagnosed between January 2010 and December 2015 localized in acral part of the extremities. Read More

    Clinical and sonographic features of pediatric soft-tissue vascular anomalies part 1: classification, sonographic approach and vascular tumors.
    Pediatr Radiol 2017 Aug 4;47(9):1184-1195. Epub 2017 Aug 4.
    Department of Diagnostic Imaging, The Hospital for Sick Children, 555 University Ave., Toronto, ON, M5G 1X8, Canada.
    Sonography can be used in the management of pediatric soft-tissue vascular anomalies for diagnosing, for assessing lesion extent and for evaluating complications and response to therapy. The sonographic technique includes a combination of gray-scale imaging with color and spectral Doppler techniques. However the interpretation of the sonographic findings requires correlation with the clinical findings, some of which can be easily obtained at the time of scanning. Read More

    Imaging features of rare mesenychmal liver tumours: beyond haemangiomas.
    Br J Radiol 2017 Nov 2;90(1079):20170373. Epub 2017 Aug 2.
    1 Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
    Tumours arising from mesenchymal tissue components such as vascular, fibrous and adipose tissue can manifest in the liver. Although histopathology is often necessary for definitive diagnosis, many of these lesions exhibit characteristic imaging features. The radiologist plays an important role in suggesting the diagnosis, which can direct appropriate immunohistochemical staining at histology. Read More

    [Tufted angiomas of the head and neck. German version].
    HNO 2017 Jul 31. Epub 2017 Jul 31.
    Klinik und Poliklinik für Hals‑, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
    Background: Tufted angiomas (TAs) are uncommon benign vascular tumors mostly located cutaneously or subcutaneously in the skin of the neck and upper trunk, which appear during childhood and grow slowly. TAs are a variant of lobular capillary hemangiomas. This is the first study to provide an overview of the current literature in combination with the authors' own clinical experience on this rare entity in the head and neck area with non-dermatological localization. Read More

    Spinal capillary hemangiomas: Two cases reports and review of the literature.
    Asian J Neurosurg 2017 Jul-Sep;12(3):556-562
    Department of Pathology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
    Hemangiomas have rarely been found in the spinal cord. A few cases of spinal capillary hemangioma have been reported since 1987. The authors reported the two cases of capillary hemangioma including the tumor at conus medullaris and the another mimicked von Hippel-Lindau disease. Read More

    Estrogen-mediated hemangioma-derived stem cells through estrogen receptor-α for infantile hemangioma.
    Cancer Manag Res 2017 7;9:279-286. Epub 2017 Jul 7.
    Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Center for Specialty Strategy Research of Shanghai Jiao Tong University China Hospital Development Institute.
    Background: Infantile hemangiomas (IHs) are the most common benign vascular tumor of infancy. They occur more frequently in female infants. The cause of hemangioma is currently unknown; however, current studies suggested the importance of estrogen (E2) signaling in hemangioma proliferation. Read More

    [Small intestinal cavernous hemangioma causing chronic hemorrhage: a case report].
    Nan Fang Yi Ke Da Xue Xue Bao 2017 Jul;37(7):866-868
    Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China.E-mail:
    Small intestinal hemangioma is a rare condition that can be divided histologically into capillary, cavernous or mixed types, among which the cavernous type is the most common. Here we report a case of small intestinal cavernous hemangioma with chronic hemorrhage in 44-year-old man. The patient complained of weakness and dizziness for 2 years that aggravated 1 month before admission accompanied by intermittent melena. Read More

    In Vivo Microvascular Pattern of Solitary Juxtapapillary Capillary Hemangioma on OCT Angiography.
    Ophthalmic Surg Lasers Imaging Retina 2017 Jul;48(7):592-595
    Juxtapapillary capillary hemangioma (JCH) is a vascular hamartoma. Fluorescein fundus angiography aids in diagnosis. The vascular morphology of this tumor has not been documented with optical coherence tomography angiography (OCTA), a new, noninvasive diagnostic modality that provides high-resolution images of vascular pattern based on blood flow in the retina and choroid. Read More

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