5,347 results match your criteria Infantile Hemangioma


Multiple renal capillary hemangiomas in a patient with end-stage renal disease.

Radiol Case Rep 2019 Jun 3;14(6):750-754. Epub 2019 Apr 3.

Department of Radiological Sciences, University of California Irvine, Orange, CA, USA.

Renal capillary hemangiomas are rare and benign vascular tumors which are typically incidentally discovered on imaging. Surgical excision is often performed, as imaging appearance is similar to malignant lesions. Renal hemangiomas are typically solitary and unilateral. Read More

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http://dx.doi.org/10.1016/j.radcr.2019.03.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449744PMC

Propranolol suppresses infantile hemangioma cell proliferation and promotes apoptosis by upregulating miR-125b expression.

Anticancer Drugs 2019 Jun;30(5):501-507

Department of Pharmacy, Fuwai Central China Cardiovascular Hospital.

Propranolol could repress infantile hemangioma cell growth and induce apoptosis. miR-125b could inhibit cell proliferation in some tumors. However, whether propranolol exerts its proliferation inhibition and apoptosis-promoting effect by regulating the expression of miR-125b needs to be further investigated. Read More

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http://dx.doi.org/10.1097/CAD.0000000000000762DOI Listing
June 2019
1 Read

Angiosarcoma of the Liver: Clinicopathologic Features and Morphologic Patterns.

Am J Surg Pathol 2019 May;43(5):581-590

Division of Anatomic Pathology, Mayo Clinic, Rochester, MN.

Angiosarcoma is a rare malignant neoplasm of the liver. The various morphologic patterns seen with angiosarcomas of the liver have not been systematically studied and their recognition remains a major diagnostic challenge. In order to provide more comprehensive data on the morphologic patterns, angiosarcomas that had been diagnosed between 1996 and 2016 at a large medical referral center were reviewed. Read More

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http://dx.doi.org/10.1097/PAS.0000000000001228DOI Listing
May 2019
4 Reads

Intraluminal capillary hemangioma of the foot presenting clinically as a neuroma: A case report.

Foot (Edinb) 2019 Apr 6;39:76-78. Epub 2019 Apr 6.

Resident Physician, Department of Podiatric Medicine & Surgery, East Liverpool City Hospital, 425 W 5th St, East Liverpool, OH 43920, USA. Electronic address:

Capillary hemangiomas are rarely seen in the foot, especially in the deeper soft tissue compartment. If left untreated, they can give rise to benign soft-tissue tumors. A rare case of a capillary hemangioma on the right dorsal medial midfoot that, because of its location adjacent to the saphenous nerve, mimicked the signs and symptoms of a neuroma. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09582592193001
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http://dx.doi.org/10.1016/j.foot.2019.03.011DOI Listing
April 2019
2 Reads

Successful Treatment of Ulcerated Infantile Hemangioma with Brimonidine-Timolol Cream: 2 Cases Report and Review of the Literature.

J Dermatolog Treat 2019 Apr 11:1-6. Epub 2019 Apr 11.

a Dermatology Department , Security Forces Hospital , Dammam , Saudi Arabia.

Ulceration is the most common complication of Infantile Hemangioma (IH). We reported 2 cases of ulcerated IH treated by new cream formulation of brimonidine 0.2%-timolol 0. Read More

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http://dx.doi.org/10.1080/09546634.2019.1603991DOI Listing
April 2019
1 Read

Topical timolol as adjunct therapy to shorten oral propranolol therapy for infantile hemangiomas.

Pediatr Dermatol 2019 Apr 9. Epub 2019 Apr 9.

Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background/objectives: First-line therapy for infantile hemangiomas (IH) is oral propranolol, a systemic beta-blocker with the risk of rare but serious adverse effects. Topical timolol presents an attractive off-label alternative with good tolerability, but sequential therapy with propranolol followed by timolol is not well studied. Here, we report effects of topical timolol preceding or following oral propranolol as adjunct therapy for IH. Read More

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http://dx.doi.org/10.1111/pde.13816DOI Listing
April 2019
1 Read

Photocoagulation for juxtapapillary retinal hemangioma in a young girl: A case report.

Mol Clin Oncol 2019 May 14;10(5):521-523. Epub 2019 Mar 14.

Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido 060-8638, Japan.

von Hippel Lindau (VHL) disease is caused by inactivation of the VHL tumor suppressor gene, resulting in formation of multiple systemic tumors. Juxtapapillary retinal capillary hemangioma (JRCH) is one of the major manifestations in VHL disease; however, treatments are challenging, especially in children. The present study reports the case of a 6-year-old girl with suspected VHL disease presenting with JRCH. Read More

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http://www.spandidos-publications.com/10.3892/mco.2019.1824
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http://dx.doi.org/10.3892/mco.2019.1824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449904PMC
May 2019
10 Reads

Complex Formation between VEGFR2 and the β-Adrenoceptor.

Cell Chem Biol 2019 Mar 14. Epub 2019 Mar 14.

Division of Physiology, Pharmacology & Neuroscience, School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, UK; Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, The Midlands, UK. Electronic address:

Vascular endothelial growth factor (VEGF) is an important mediator of endothelial cell proliferation and angiogenesis via its receptor VEGFR2. A common tumor associated with elevated VEGFR2 signaling is infantile hemangioma that is caused by a rapid proliferation of vascular endothelial cells. The current first-line treatment for infantile hemangioma is the β-adrenoceptor antagonist, propranolol, although its mechanism of action is not understood. Read More

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http://dx.doi.org/10.1016/j.chembiol.2019.02.014DOI Listing
March 2019
1 Read

Multifocal Infantile Hemangioma.

J Pediatr 2019 Apr 4. Epub 2019 Apr 4.

Department of General Pediatrics, Tokyo Metropolitan Children's Medical Center, Fuchu, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jpeds.2019.02.048DOI Listing
April 2019
1 Read

Renal Cell Carcinoma With Hemangioma-Like Features: Diagnostic Implications and Review of the Literature.

Int J Surg Pathol 2019 Apr 8:1066896919840435. Epub 2019 Apr 8.

2 Yonsei University, Seoul, Republic of Korea.

Renal cell carcinoma (RCC) with clear cell morphology may show a prominent delicate vascularity. In this article, we report the morphologic and immunohistochemical features of a clear cell papillary RCC mimicking hemangioblastoma and a clear cell RCC mimicking hemangioma. Case 1 showed tubular and papillary growth of clear cells with distinctive areas of capillary proliferation and admixed stromal-like cells resembling a hemangioblastoma. Read More

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http://dx.doi.org/10.1177/1066896919840435DOI Listing
April 2019
1 Read

Neonatal Cardiac Arrest From Left Ventricular Cardiac Hemangioma: A Surprising Presentation.

Can J Cardiol 2019 Apr 13;35(4):544.e3-544.e5. Epub 2019 Feb 13.

Services de Chirurgie Cardiovasculaire Pédiatrique, Québec-Université Laval, Quebec City, Quebec, Canada.

Cardiac hemangioma is rare, even more when leading to a cardiovascular collapse in a seemingly healthy newborn. A 6-day-old neonate had a tamponade caused by a basolateral hemangioma of the left ventricle. Partial surgical resection was performed. Read More

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http://dx.doi.org/10.1016/j.cjca.2019.01.023DOI Listing
April 2019
4 Reads

Poikilodermatous plaque-like hemangioma: case series of a newly defined entity.

J Am Acad Dermatol 2019 Mar 28. Epub 2019 Mar 28.

Department of Dermatopathology, St. John's Institute of Dermatology, Guys and St Thomas' Foundation Trust, London, UK.

Background: We present a distinctive type of acquired vascular proliferation, for which we propose the name of poikilodermatous plaque-like hemangioma (PPH).

Objective: The aim of the study is to summarise the clinical and histopathological features in a case series of PPH.

Methods: Sixteen cases were identified from the routine clinical and referral practice of the authors. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.03.069DOI Listing
March 2019
6 Reads

Objective evaluation of infantile hemangiomas response to propanolol treatment using a 3D imaging system.

Br J Dermatol 2019 Mar 28. Epub 2019 Mar 28.

Department of Dermatology, ASST Spedali Civili di Brescia, Brescia, Italy.

Infantile hemangioma (IH) is the most common benign vascular tumor of infancy. IHs follow a typical course: they appear within few days to weeks after birth and usually grow rapidly during the first year of life, sometimes continuing up to 24 months. After a period of stabilization lasting few months, IHs undergo spontaneous involution. Read More

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http://dx.doi.org/10.1111/bjd.17925DOI Listing

Clinical and radiological outcomes of infantile hemangioma treated with oral propranolol: A long-term follow-up study.

J Dermatol 2019 Mar 27. Epub 2019 Mar 27.

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Infantile hemangiomas (IH) undergo rapid growth during early infancy followed by gradual involution. After involution, a part of IH remain as residual lesions. Since 2008, oral propranolol has been widely used in the treatment of IH. Read More

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http://dx.doi.org/10.1111/1346-8138.14853DOI Listing
March 2019
3 Reads

Pulmonary Infantile Hemangioma Mimicking a Congenital Cystic Adenomatoid Malformation.

Pediatr Dev Pathol 2019 Mar 26:1093526619838743. Epub 2019 Mar 26.

2 Department of Pathology, Hôpital Femme Mère Enfant, CHU de Lyon, Bron, France.

Infantile hemangioma (IH) is the most common benign vascular tumor of infancy, occurring predominantly in the head and neck. It is characterized by specific endothelial expression of glucose transporter-1 (GLUT-1) and involution with time, spontaneous or on beta-blockers treatment. Although some predisposing factors are known, the exact pathogenesis remains unclear. Read More

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http://dx.doi.org/10.1177/1093526619838743DOI Listing
March 2019
1 Read

Silence of long non-coding RNA UCA1 inhibits hemangioma cells growth, migration and invasion by up-regulation of miR-200c.

Life Sci 2019 Mar 18. Epub 2019 Mar 18.

Department of Pediatric Surgery, Weifang People's Hospital, Weifang 261000, China. Electronic address:

Background: Human urothelial carcinoma associated 1 (UCA1) has been recognized as an oncogenic lncRNA in various cancers, except infantile hemangioma (IH). This study attempts to explore the functional role of lncRNA UCA1 in IH.

Methods: qRT-PCR was carried out to detect the expression of lncRNA UCA1 in human IH tissues. Read More

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http://dx.doi.org/10.1016/j.lfs.2019.03.038DOI Listing
March 2019
2 Reads

The Use of OCT and OCT Angiography in Detecting an Atypical Case of Retinal Capillary Hemangioma.

Ophthalmic Surg Lasers Imaging Retina 2019 Mar;50(3):e81-e83

Retinal capillary hemangioma (RCH) is a benign retinal tumor defined by a vascular proliferation localized in the peripheral retina, juxtapapillary retina, or the intraneural portion of the optic nerve. In most cases, diagnosis of RCH is performed by fundus evaluation and confirmed by fluorescein fundus angiography. Nevertheless, a small RCH localized on or adjacent to the optic nerve head could be difficult to detect by fundus examination. Read More

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https://www.healio.com/doiresolver?doi=10.3928/23258160-2019
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http://dx.doi.org/10.3928/23258160-20190301-17DOI Listing
March 2019
6 Reads

Location of infantile hemangioma is a predictor of volumetric sequelae after involution.

J Dermatol 2019 Mar 19. Epub 2019 Mar 19.

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Although infantile hemangiomas (IH) spontaneously involute, some leave more volumetric sequelae than others. Identifying predictors of such sequelae would provide a management reference for IH lesions and help achieve favorable outcomes. Our objective is to explore the correlation between volumetric residue remaining after IH involution and its location and to identify other potential outcome predictors. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1346-8138.14
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http://dx.doi.org/10.1111/1346-8138.14847DOI Listing
March 2019
13 Reads

Papillary hemangioma in the spinal canal of a patient with a germline 12p microdeletion.

Histopathology 2019 Mar 18. Epub 2019 Mar 18.

Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Spinal hemangiomas, though frequent in the vertebrae, are rare in the spinal canal with only slightly over 100 purely epidural cases reported to date, most of them classified as either cavernous or capillary hemangiomas . Papillary hemangiomas are rare tumors that were previously described as distinctive benign cutaneous lesions that appear as solitary bluish papules in the head and neck . We describe the first report of this neoplasm arising in the spinal canal and discuss the cytogenetic findings of this rare, possibly syndromic, disease entity. Read More

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http://dx.doi.org/10.1111/his.13861DOI Listing
March 2019
1 Read

High-frequency ultrasonography and contrast-enhanced ultrasound for the evaluation of testicular capillary hemangioma: A case report.

Medicine (Baltimore) 2019 Mar;98(11):e14779

Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, China.

Rationale: Testicular capillary hemangioma (TCH) is a rare benign tumor of the testis. To the authors' knowledge, there is currently only a few literatures describing the use of contrast-enhanced ultrasound (CEUS) to diagnose TCH. Accurate preoperative diagnosis of benign tumors can avoid orchiectomy. Read More

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http://dx.doi.org/10.1097/MD.0000000000014779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426614PMC
March 2019
2 Reads

Vascular tumors in infants and adolescents.

Insights Imaging 2019 Mar 13;10(1):30. Epub 2019 Mar 13.

Universitätsklinik und Poliklinik für Radiologie, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany.

Malignant vascular tumors as part of the vascular anomalies spectrum are extremely rare in children and young adults. Instead, benign vascular neoplasias are frequently encountered in the pediatric patient population. While vascular malformations are congenital vascular lesions, originating from a mesenchymal stem cell defect, vascular tumors are neoplastic transformations of endothelial and other vascular cells. Read More

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https://insightsimaging.springeropen.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s13244-019-0718-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419671PMC
March 2019
2 Reads

Insulin-like growth factor 2 promotes the adipogenesis of hemangioma-derived stem cells.

Exp Ther Med 2019 Mar 24;17(3):1663-1669. Epub 2018 Dec 24.

Department of Anatomy, Anhui Medical University, Hefei, Anhui 230031, P.R. China.

Infantile hemangioma (IH), which is the most common tumor in infants, is characterized by rapid proliferation followed by spontaneous regression into fibro-fatty tissue in childhood. However, its specific mechanism has not been clarified. Our previous studies showed that insulin-like growth factor 2 (IGF-2) is increased in the proliferative phase of IH, which is deemed to form from hemangioma-derived stem cells (HemSC). Read More

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http://www.spandidos-publications.com/10.3892/etm.2018.7132
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http://dx.doi.org/10.3892/etm.2018.7132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396001PMC
March 2019
8 Reads
0.941 Impact Factor

A Life Threating Subglottic and Mediastinal Hemangioma in an Infant.

J Craniofac Surg 2019 Mar 6. Epub 2019 Mar 6.

Umraniye Research and Education Hospital. Department of Otolaryngology, Istanbul, Turkey.

Subglottic and mediastinal hemangioma are rare benign vascular tumors of childhood. They cause potentially life threatening condition which requires intervention. Several therapeutic options have been described in the literature with varying degrees of success and complications. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005340DOI Listing
March 2019
1 Read

Infantile cardiac hemangioma causing right ventricular inflow obstruction.

Asian Cardiovasc Thorac Ann 2019 Mar 12:218492319836899. Epub 2019 Mar 12.

1 Cardiothoracic Surgery Division, Department of Surgery, Srinagarind Hospital and Queen Sirikit Heart Center of the Northeast, Faculty of Medicine, Khon Kaen University, Thailand.

Cardiac hemangiomas are extremely rare tumors, especially in infants. We present the case of a 4-month-old girl who developed cyanosis due to a large right atrial tumor causing right ventricular inflow obstruction. The patient underwent emergency surgery for tumor resection and recovered uneventfully. Read More

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http://dx.doi.org/10.1177/0218492319836899DOI Listing
March 2019
2 Reads

The efficacy of low-dose propranolol treatment in infantile hemangioma and the results of intralesional bleomycin injection in patients unresponsive to propranolol.

Pediatr Int 2019 Mar 12. Epub 2019 Mar 12.

Division of Pediatric Hematology/Onkology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, TURKEY.

Background: Infantile hemangioma (IH) is the most common form of benign childhood vascular tumors. Mostly resolve spontaneously; however, treatment is recommended in patients who develop complication. Propranolol is recommended as first-line therapy by authors, while the treatment of choice in patients who are unresponsive to first-line therapy depends on the clinical experiences of each center. Read More

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http://dx.doi.org/10.1111/ped.13830DOI Listing

Intraneural Hemangioma: Case Report of a Rare Tibial Nerve Lesion.

Cureus 2018 Dec 27;10(12):e3784. Epub 2018 Dec 27.

Radiology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, USA.

An intraneural hemangioma is a rare, benign mesodermal lesion. We present a case of a three-year-old female with the inability to straighten her right knee and fullness over the right popliteal fossa for one year. Magnetic resonance imaging (MRI) demonstrated a T2 hyperintense lesion of the popliteal fossa, within the tibial nerve. Read More

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http://dx.doi.org/10.7759/cureus.3784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395016PMC
December 2018
1 Read

Parkes Weber syndrome presenting as Stewart-Bluefarb acroangiodermatitis.

BMJ Case Rep 2019 Mar 8;12(3). Epub 2019 Mar 8.

Department of General Surgery, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Parkes Weber syndrome (PWS) is a rare disorder characterised by arteriovenous (AV) fistula, along with capillary, lymphatic, venous malformations and limb hypertrophy. Stewart-Bluefarb syndrome is a variant of acroangiodermatitis, which is associated with congenital AV malformation/fistulas. It usually begins early in life, unilaterally over lower extremities presenting as violaceous to dusky coloured macules, papules or plaques with tendency to ulcerate. Read More

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http://dx.doi.org/10.1136/bcr-2018-227793DOI Listing
March 2019
3 Reads

Linc00152 knockdown inactivates the Akt/mTOR and Notch1 pathways to exert its anti-hemangioma effect.

Life Sci 2019 Apr 6;223:22-28. Epub 2019 Mar 6.

Department of Hemangioma and Vascular Malformation, Henan Provincial People's Hospital, Zhengzhou 450003, China. Electronic address:

Aims: Infantile hemangioma (IH) is one of the most common benign vascular tumors occurred in infants. Linc00152 is a kind of long non-coding RNAs (lncRNAs) and acts as a tumor oncogene. Recent study reported that Linc00152 is highly expressed in clinical IH tissues. Read More

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http://dx.doi.org/10.1016/j.lfs.2019.03.006DOI Listing
April 2019
1 Read

Lobular Capillary Hemangioma in Post-Pneumonectomy Bronchial Stump.

Arch Bronconeumol 2019 Mar 5. Epub 2019 Mar 5.

Servicio de Anatomía Patológica, Hospital Clínico Universitario de Valladolid, Valladolid, España; Centro de Investigación en Red Enfermedades Respiratorias (CIBERES).

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http://dx.doi.org/10.1016/j.arbres.2019.01.029DOI Listing
March 2019
1 Read

T3 infantile hemangioma: first case of a tumor involving epidural, intradural extramedullary, and intradural intramedullary spaces.

J Neurosurg Pediatr 2019 Mar 8:1-5. Epub 2019 Mar 8.

Infantile hemangiomas (IHs) are the most common benign neoplasm of the neonatal and newborn period, affecting approximately 5% of infants. However, true IHs presenting in the neuraxis are quite rare with only 15 documented cases in the literature. Management of IH consists of utilizing steroids and immunomodulatory therapies to reduce the size of the tumor and surgery to remove the tumor to decrease symptoms and the risk of bleeding. Read More

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http://dx.doi.org/10.3171/2018.12.PEDS18554DOI Listing

Retracted: Mechanisms of Action of MicroRNAs in Infantile Hemangioma Tissue and Vascular Endothelial Cells in Different Periods.

Med Sci Monit 2019 03 7;25:1759. Epub 2019 Mar 7.

Biobank, 1st Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China (mainland).

The article is withdrawn by the authors request. Read More

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http://dx.doi.org/10.12659/MSM.915959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422424PMC
March 2019
2 Reads

Clinical and Ultrasonographic Evaluation of Infantile Periocular Hemangioma Treated With Oral Propranolol.

Ophthalmic Plast Reconstr Surg 2019 Mar 4. Epub 2019 Mar 4.

Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Purpose: To evaluate the clinical and ultrasonographic response of periocular infantile capillary hemangioma during treatment with oral propranolol.

Methods: Patients with infantile periocular hemangioma and visual or cosmetic concerns were enrolled in this prospective interventional case series. Propranolol was given at a dose of 2 mg/kg per day for at least 6 months. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001336DOI Listing
March 2019
7 Reads

Secondary Congenital Glaucoma Associated With Retro-orbital Infantile Hemangioma: A Masquerade Syndrome.

J Glaucoma 2019 Mar 6. Epub 2019 Mar 6.

University Hospital Nord, Chemin des Bourrely, Marseille, France.

Purpose: The main purpose of this study was to describe a unique case of retro-orbital infantile hemangioma (IH) simulating a congenital glaucoma requiring prompt management with systemic propranolol.

Study Design: This was a case report.

Results: A 2-month-old white female was referred to our department of ophthalmology for progressive, unilateral protrusion of the left eye associated with epiphora. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001227DOI Listing
March 2019
7 Reads

Propranolol-Loaded Mesoporous Silica Nanoparticles for Treatment of Infantile Hemangiomas.

Adv Healthc Mater 2019 Mar 6:e1801261. Epub 2019 Mar 6.

The Economic and Technological Development Zone People's Hospital of Linyi City, Linyi, Shandong, 276023, China.

Infantile hemangioma (IH) is one of the most common neoplasm of infancy. Although with the potential to involute slowly after proliferation, IH has several subsets that could develop severe complications and lead to functional impairment or permanent disfigurement. In the present study, a novel propranolol (PRN) delivery system is developed that encapsulated in mesoporous silica nanoparticles (MSN). Read More

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http://dx.doi.org/10.1002/adhm.201801261DOI Listing
March 2019
2 Reads
4.880 Impact Factor

Intralesional injection of bevacizumab versus triamcinolone acetonide in infantile hemangioma.

J Dermatolog Treat 2019 Mar 5:1-6. Epub 2019 Mar 5.

a Department of Dermatology, Venereology and Andrology, Faculty of Medicine , Benha University , Benha , Egypt.

Background: Infantile hemangioma (IH) in most cases can be a self-limited condition; however, it may be ulcerated, infected, causing organ function disability and even death. Vascular endothelial growth factor (VEGF) has a role in IH. Bevacizumab is a monoclonal antibody against VEGF-A. Read More

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http://dx.doi.org/10.1080/09546634.2019.1590521DOI Listing

Spinal epidural capillary hemangioma: case report and review of the literature.

Br J Neurosurg 2019 Mar 4:1-4. Epub 2019 Mar 4.

a Department of Neuroscience, Neurosurgery , AOU Cittá della Salute e della Scienza di Torino , Turin , Italy.

Background: Almost all of the epidural hemangiomas reported are cavernous hemangiomas. Purely extradural spinal capillary hemangiomas are very rare. Capillary hemangiomas are hamartomatous malformations that result from proliferations of vascular endothelial cells. Read More

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http://dx.doi.org/10.1080/02688697.2018.1562034DOI Listing
March 2019
1 Read

Progressive infantile hepatic hemangioma not responding to propranolol.

J Dermatol 2019 Mar 1. Epub 2019 Mar 1.

Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1111/1346-8138.14833DOI Listing
March 2019
3 Reads

Diagnosis and Management of Infantile Hemangiomas in the Neonate.

Pediatr Clin North Am 2019 04;66(2):437-459

Division of Dermatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, 225 East Chicago Avenue, Box 107, Chicago, IL 60611-2605, USA. Electronic address:

Infantile hemangiomas (IH) are a common benign tumor of infancy, most being uncomplicated and not requiring therapy. Some IH may require treatment; the pediatric provider must be familiar with morphology, distribution, natural history, and associations of IH. Several treatment options are available for IH: current standard of care, oral propranolol. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.12.011DOI Listing
April 2019
1 Read

Central Nervous System Effects of Oral Propranolol for Infantile Hemangioma: A Systematic Review and Meta-Analysis.

J Clin Med 2019 Feb 22;8(2). Epub 2019 Feb 22.

Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.

Concerns about the effects of propranolol on the central nervous system (CNS) in the infantile hemangioma (IH) population have been raised. We conducted a meta-analysis of the CNS and sleep-related effects of oral propranolol in IH patients. PubMed, Embase, Cochrance, Web of Science, and Clinicaltrials. Read More

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http://dx.doi.org/10.3390/jcm8020268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406625PMC
February 2019
2 Reads

Use of AccuVein AV400 for identification of probable RICH.

JAAD Case Rep 2019 Mar 12;5(3):213-215. Epub 2019 Feb 12.

Division of Dermatology, University of Alberta, Edmonton, Alberta.

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http://dx.doi.org/10.1016/j.jdcr.2018.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374947PMC
March 2019
1 Read

Outcomes of surgical treatment for hemangiomas.

Pediatr Dermatol 2019 Mar 22;36(2):207-212. Epub 2019 Feb 22.

Department of Biostatistics & Bioinformatics, Duke University, Durham, North Carolina.

Objective: To quantify complications and rates of adverse events associated with surgical excision of hemangiomas in children using a national surgical database.

Data Source: Pediatric American College of Surgeons (ACS) National Surgical Quality Improvement Program (ACS NSQIP -pediatric), years 2012-2016.

Methods: Subjects included children under 18 years with a postoperative diagnosis of International Classification of Diseases (ICD), 9th revision code: 228. Read More

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http://dx.doi.org/10.1111/pde.13751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428594PMC
March 2019
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[Magnetic Resonance Imaging of the Orbital Cavity: Indications and Diagnostic Possibilities].

Klin Monbl Augenheilkd 2019 Mar 18;236(3):321-339. Epub 2019 Feb 18.

Today, magnetic resonance imaging (MRI) is considered the diagnostic tool of choice for eye and orbital pathologies. In this article, the MR image characteristics of relevant pathologies are illustrated with case-based examples in the context of clinical findings. Vascular pathologies (such as capillary and cavernous hemangioma), inflammatory diseases (such as endocrine orbitopathy), and neoplasms (such as lymphoma, uveal melanoma, retinoblastoma, and ocular/orbital metastasis) are described. Read More

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http://dx.doi.org/10.1055/a-0849-0000DOI Listing
March 2019
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Current Treatment and Management of Infantile Hemangiomas.

Surv Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Department of Ophthalmology, University of Washington, WA, USA; Department of Oculoplastic and Reconstructive Surgery, University of Washington, WA, USA. Electronic address:

Infantile hemangiomas (IHs), otherwise known as infantile capillary hemangiomas, strawberry hemangiomas, or strawberry nevi, are non-malignant vascular tumors that commonly affect children. The natural disease course typically involves growth for up to a year followed by regression without treatment over a period of years, with no cosmetic or functional sequelae. Less commonly, however, IHs can become a threat to vision or even life depending on location and size of the lesion. Read More

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http://dx.doi.org/10.1016/j.survophthal.2019.02.005DOI Listing
February 2019
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Central Effects of Beta-Blockers May Be Due to Nitric Oxide and Hydrogen Peroxide Release Independently of Their Ability to Cross the Blood-Brain Barrier.

Front Neurosci 2019 31;13:33. Epub 2019 Jan 31.

INSERM U1220 Institut de Recherche en Santé Digestive, CHU Purpan, Université Toulouse III Paul Sabatier, Toulouse, France.

Propranolol is the first-line treatment for infants suffering from infantile hemangioma. Recently, some authors raised the question of potential neurologic side effects of propranolol due to its lipophilic nature and thus its ability to passively cross the blood-brain barrier (BBB) and accumulate into the brain. Hydrophilic beta-blockers, such as atenolol and nadolol, where therefore introduced in clinical practice. Read More

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https://www.frontiersin.org/article/10.3389/fnins.2019.00033
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http://dx.doi.org/10.3389/fnins.2019.00033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365417PMC
January 2019
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