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    4811 results match your criteria Infantile Hemangioma

    1 OF 97

    In Vivo Microvascular Pattern of Solitary Juxtapapillary Capillary Hemangioma on OCT Angiography.
    Ophthalmic Surg Lasers Imaging Retina 2017 Jul;48(7):592-595
    Juxtapapillary capillary hemangioma (JCH) is a vascular hamartoma. Fluorescein fundus angiography aids in diagnosis. The vascular morphology of this tumor has not been documented with optical coherence tomography angiography (OCTA), a new, noninvasive diagnostic modality that provides high-resolution images of vascular pattern based on blood flow in the retina and choroid. Read More

    microRNA-143 acts as a suppressor of hemangioma growth by targeting Bcl-2.
    Gene 2017 Jul 14. Epub 2017 Jul 14.
    Department of Vascular Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
    Infantile hemangioma is the most common vascular tumor affecting infants, which is associated with clonal expansion of endothelial cells. The aim of this study is to determine the role of microRNA (miR)-143 in the growth and survival of hemangioma-derived endothelial cells (HemECs). We examined the expression of miR-143 in patients with proliferating-phase (n=10) and involuting-phase (n=8) hemangiomas. Read More

    Spinal epidural capillary hemangioma: A rare case report with a review of literature.
    Surg Neurol Int 2017 21;8:123. Epub 2017 Jun 21.
    Department of Neuropathology, NIMHANS, Bengaluru, Karnataka, India.
    Background: Purely epidural capillary hemangiomas are very rare. There are only 6 such reports.

    Case Description: A 50-year-old male presented with a progressive lower extremity paraparesis. Read More

    Posttraumatic Progressive Vertebral Hemangioma Induced by a Fracture.
    Case Rep Surg 2017 20;2017:8280678. Epub 2017 Jun 20.
    Department of Neurosurgery, Bahçeşehir University Faculty of Medicine, Istanbul, Turkey.
    The authors present an extremely rare case of an aggressive and progressive vertebral capillary hemangioma of the lumbar spine secondary to a trauma. A 40-year-old man who complained of back and leg pain due to a hemangioma of L1 that had begun a year after the fracture of the same vertebra was subsequently operated on. Due to the profuse bleeding, only a subtotal removal was possible. Read More

    M1 Macrophage-Induced Endothelial-to-Mesenchymal Transition Promotes Infantile Hemangioma Regression.
    Am J Pathol 2017 Jul 12. Epub 2017 Jul 12.
    Center for Regenerative Medicine, Department of Orthopaedics, Warren Alpert Medical School of Brown University, Providence, Rhode Island; Division of Hematology/Oncology, Warren Alpert Medical School of Brown University, Providence, Rhode Island. Electronic address:
    Infantile hemangiomas are benign tumors of vascular endothelial cells (ECs), characterized by three distinct stages: proliferating phase, involuting phase, and involuted phase. The mechanisms that trigger involution of hemangioma into fibro-fatty tissue remain unknown. We report a novel mechanism by which M1-polarized macrophages induce endothelial-to-mesenchymal transition (EndMT) and promote hemangioma regression. Read More

    Intradural Extramedullary Capillary Hemangioma In the Upper Thoracic Spine with Simultaneous Extensive Arachnoiditis.
    Korean J Spine 2017 Jun 30;14(2):57-60. Epub 2017 Jun 30.
    Department of Neurosurgery, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Korea.
    Capillary hemangiomas are common benign vascular tumors on skin and soft tissues, but developing as an intradural and extramedullary (IDEM) tumor in spine is extremely rare. In this report, we present IDEM tumor compressing thoracic cord in T2-3 level with extensive arachnoiditis below the tumor level in a 60-year-old man. The lesion was removed and histological diagnosis was capillary hemangioma. Read More

    Topical Application of 0.5% Timolol Maleate Hydrogel for the Treatment of Superficial Infantile Hemangioma.
    Front Oncol 2017 27;7:137. Epub 2017 Jun 27.
    Department of Interventional Therapy, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
    The therapeutic options for infantile hemangiomas (IHs) have been greatly altered since the introduction of oral propranolol for successful treatments of IHs. Recently, there is an increase in the application of topical timolol maleate for treating superficial IHs. In the present study, we developed a new formulation of timolol maleate 0. Read More

    Congenital Progressive Mutilating Hemangioma.
    Open Access Maced J Med Sci 2017 Jun 11;5(3):395-396. Epub 2017 Jun 11.
    "Onkoderma" - Policlinic for Dermatology and Dermatologic Surgery, Sofia, Bulgaria.
    A 73-year-old male patient was admitted with symptoms of decompensated cardiac and pulmonary insufficiency with long-lasting history. A tumor-like formation was observed within the clinical examination, covering the whole skin of the nose, paranasal region of the left part of the face, as well as the upper and lower left eyelids. The lesion was with yellow to brownish surface and dark-reddish to violet discolored peripheral area, composed of nodular formations, smooth central surface and firm texture on palpation. Read More

    Clinical Evaluation of Color Doppler Ultrasound in Selecting the Optimal Treatment Modality for Infantile Hemangioma(△).
    Chin Med Sci J 2017 Jun;32(2):100-106
    Department of Dermatology, the First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China.
    Objective We investigated the efficacy and safety of 1064 nm Nd: YAG laser, intense pulsed light (IPL), and lauromacrogol injection in the treatment of hemangioma, in order to evaluate the value of color Doppler ultrasound guidance in choosing the optimal treatment modality. Methods Infantile patients who were clinical diagnosed as hemangiomas were randomly divided into group A, who had color Doppler ultrasound examinations before the treatment, and group B who had the treatment without ultrasound evaluation. Patients in the group A were assigned into subgroups according to the depth of lesion by sonography: group A-1 for those who had a lesion depth <1. Read More

    [Usage and efficacy of timolol maleate eye drops in treatment of superficial infantile hemangioma].
    Zhong Nan Da Xue Xue Bao Yi Xue Ban 2017 Jun;42(6):657-661
    Department of Plastic Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
    Objective: To determine drug dose and usage of timolol maleate eye drops in the treatment of superficial infantile hemangioma.
 Methods: A total of 250 superficial hemangioma infants were recruited and assigned into 5 groups (n=50 for each group): an external application group and 4 exterior coating groups (2, 4, 6, 8 times per day). We evaluated the therapeutic effect of different methods for drug application (external application or exterior coating) and the frequency for drug administration on superficial infantile hemangioma. Read More

    RNF213 variants in a child with PHACE syndrome and moyamoya vasculopathy.
    Am J Med Genet A 2017 Jul 7. Epub 2017 Jul 7.
    Departments of Dermatology and Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin.
    Segmental infantile hemangiomas (IH) can be associated with congenital anomalies in a regional distribution. PHACE refers to large cervicofacial segmental IH in association with congenital anomalies of the aortic arch and medium-sized arteries of the head and neck, as well as structural anomalies of the posterior fossa and eye. A subset of PHACE patients have arterial anomalies that progress to moyamoya vasculopathy (MMV). Read More

    Infatile hemangiomas with minimal or arrested growth associated with soft tissue hypertrophy: a case series of 10 patients.
    J Eur Acad Dermatol Venereol 2017 Jul 5. Epub 2017 Jul 5.
    Dermatology department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
    Background: Infantile hemangiomas with minimal or arrested growth (IH-MAGs) are characterized by a proliferative component of less than 25% of its surface area. The co-occurrence of IH-MAGs and soft tissue anomalies is rare and case series of this association are lacking.

    Objective: We present ten cases of IH-MAGs associated with soft tissue hypertrophy and describe their clinical features. Read More

    Incidence, Treatment Patterns, and Health Care Costs of Infantile Hemangioma: Results of a Retrospective German Database Analysis.
    Pediatr Dermatol 2017 Jul 4;34(4):450-457. Epub 2017 Jul 4.
    Pierre Fabre Pharma, Freiburg, Germany.
    Objectives: To determine the incidence, effect (defined according to treatment rate), and health care costs of infantile hemangiomas (IHs) in Germany from 2007 to 2012 by analyzing patient data of German statutory health insurances.

    Methods: A retrospective analysis using data from a database matched with the overall population covered by German statutory health insurance was performed. To describe the treatment rate and costs of IHs, a search algorithm was developed dividing the study population into three groups (patients with IHs, patients with IHs possibly requiring treatment, and patients with IHs receiving treatment). Read More

    Tufted angiomas of the head and neck.
    HNO 2017 Jun 30. Epub 2017 Jun 30.
    Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Background: Tufted angiomas (TAs) are uncommon benign vascular tumors mostly located cutaneously or subcutaneously in the skin of the neck and upper trunk, which appear during childhood and grow slowly. TAs are a variant of lobular capillary hemangiomas. This is the first study to provide an overview of the current literature in combination with the authors' own clinical experience on this rare entity in the head and neck area with non-dermatological localization. Read More

    Repurposing propranolol as a drug for the treatment of retinal haemangioblastomas in von Hippel-Lindau disease.
    Orphanet J Rare Dis 2017 Jun 29;12(1):122. Epub 2017 Jun 29.
    Centro de Investigaciones Biológicas, CSIC, Madrid, Spain.
    Background: Von Hippel-Lindau (VHL) disease is a rare oncological disease with an incidence of 1:36,000, and is characterized by the growth of different types of tumours. Haemangioblastomas in the central nervous system (CNS) and retina, renal carcinoma and pheochromocytomas are the most common tumours. The absence of treatment for VHL leads to the need of repeated surgeries as the only option for these patients. Read More

    Update on classification and diagnosis of vascular malformations.
    Curr Opin Pediatr 2017 Aug;29(4):448-454
    CHU Sainte-Justine, University of Montreal, Montreal, Québec, Canada.
    Purpose Of Review: This review provides an update of the classification in the classification of vascular anomalies since April 2014 at the International Society for the Study of Vascular Anomalies meeting in Melbourne, Australia.

    Recent Findings: The reader will become familiar with how to diagnose the major vascular malformations, including capillary, venous, arteriovenous, and lymphatic and combinations thereof. In addition, vascular malformation syndromes, including those with overgrowth, will be clarified. Read More

    BIlateral juxtapapillary retinal capillary haemangioma: Usefulness of aflibercept in the management of its complications.
    Arch Soc Esp Oftalmol 2017 Jun 23. Epub 2017 Jun 23.
    Servicio de Oftalmología, Hospital Virgen del Puerto, Plasencia (Cáceres), España.
    Case Report: A 45 year-old man with a history of adrenal phaeochromocytoma presented with a subretinal juxtapapillary haemorrhage on his left eye and a small asymptomatic vascular tumour in the contralateral eye. With the mentioned findings, the patient was diagnosed with bilateral retinal capillary haemangioma in the context of a von Hippel Lindau disease. Intravitreal aflibercept was prescribed, with a good outcome of the disease. Read More

    Tissue and serum mRNA profile of MMPs-2/9 as a potential novel biomarker for the most individual approach in infantile hemangiomas and cancer disease.
    Immunobiology 2017 Jun 3. Epub 2017 Jun 3.
    Department of Pediatric Surgery and Oncology, Central Clinical Hospital of Medical University of Lodz, Konopnicka Memorial Pediatric Center, ul. Sporna 36/50, 91-738 Lodz, Poland.
    Propranolol is a widely-known beta-blocker approved for treating infantile hemangiomas (IH). The mechanisms behind the spectacular IH involution after propranolol treatment remain unclear. Recently, there is strong evidence of overexpression of numerous angiogenic factors in IH tissues, and it is reported that propranolol influences their pathways. Read More

    [Pediatric salivary gland tumors and tumor-like lesions].
    Pathologe 2017 Jul;38(4):294-302
    Klinik für Hals‑, Nasen- und Ohrenheilkunde (HNO), Klinikum Augsburg, Sauerbruchstraße 6, 86156, Augsburg, Deutschland.
    Salivary gland tumors and tumor-like lesions in the pediatric population are uncommon. They comprise a heterogeneous group of infectious/inflammatory and neoplastic conditions. Pediatric salivary neoplasms include benign tumors of mesenchymal or epithelial origin as well as malignancies of epithelial (carcinomas), mesenchymal (sarcoma) or hematolymphoid (lymphoma) derivation. Read More

    Circulating Levels of Vascular Endothelial Growth Factor and Basic Fibroblastic Growth Factor in Infantile Hemangioma Versus Vascular Malformations.
    Clin Appl Thromb Hemost 2017 Jan 1:1076029617710333. Epub 2017 Jan 1.
    2 Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
    Few preliminary reports studied the utility of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) for differentiation between infantile hemangiomas (IHs) and vascular malformations. The aim of this study was to investigate the role of serum VEGF and bFGF levels in differentiating IHs from vascular malformations and identifying the stage and clinical course of IHs. Serum levels of VEGF and bFGF were assessed in 60 infants and children with various cutaneous vascular anomalies defined in 3 groups: proliferating IHs (n = 25), involuting IHs (n = 23), and vascular malformations (n = 12), in comparison with their levels in 40 healthy matched control. Read More

    Diffuse hepatic hemangioma with single cutaneous hemangioma: an alerting occurrence.
    Clin Case Rep 2017 Jun 24;5(6):887-890. Epub 2017 Apr 24.
    Department of PediatricsMakassed General HospitalBeirutLebanon.
    Screening of infants with five or more cutaneous infantile hemangiomas with abdominal ultrasound is often recommended. However, diffuse hepatic hemangioma can develop even in patients with single cutaneous hemangioma. This highlights the importance of physical examination and screening ultrasound in these patients. Read More

    Sildenafil suppresses the proliferation and enhances the apoptosis of hemangioma endothelial cells.
    Exp Ther Med 2017 Jun 5;13(6):2645-2650. Epub 2017 Apr 5.
    Department of Oral and Maxillofacial Surgery, Qilu Hospital, Shandong University, Jinan, Shandong 250012, P.R. China.
    Treatment of infantile hemangiomas (IH) with propranolol was first reported in 2008. Regressions of lymphatic malformations combined with pulmonary hypertension was first reported in 2012 after three children received treatment with oral sildenafil, which serves as an antagonist of phosphodiesterase isoform-5 (PDE-5). A marked expression of endothelial cells in the cytoplasm of IH tissues was obtained in our previous study. Read More

    Giant pyogenic granuloma of the finger in an HIV-positive patient.
    J Eur Acad Dermatol Venereol 2017 May 30. Epub 2017 May 30.
    Department of Dermatology, Tel-Aviv Sourasky Medical Center.
    Pyogenic granuloma (PG) is an acquired vascular lesion that affects the skin and mucosa. The term Lobular Capillary Hemangioma was subsequently adopted to more accurately reflect its biologic and histopathologic nature [1]. Clinically, PGs usually appear as single, small, red papules with a marked tendency for bleeding. Read More

    Atenolol Versus Propranolol for Treatment of Infantile Hemangiomas During the Proliferative Phase: A Retrospective Noninferiority Study.
    Pediatr Dermatol 2017 Jul 28;34(4):413-421. Epub 2017 May 28.
    Department of Cardiology, Connecticut Children's Medical Center, Hartford, Connecticut.
    Background/objectives: The nonselective beta-blocker propranolol is the current criterion standard for treatment of infantile hemangiomas (IHs) and the first therapy that the U.S. Food and Drug Administration has approved for the condition, but concern about adverse effects, such as bronchospasm, hypoglycemia, and sleep disturbances, has sparked interest in the use of alternative agents such as the selective β1 antagonist atenolol. Read More

    Congenital Capillary Proliferation of the Kidney: A Distinctive Renal Vascular Lesion of Childhood.
    Hum Pathol 2017 May 26. Epub 2017 May 26.
    Department of Pathology and Laboratory Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg School of Medicine -, Chicago, IL.
    Renal vascular lesions (RVL) are rare and their morphological spectrum remains largely unknown, particularly in children. In this study, we characterize the clinicopathological features of RVL in a cohort of twelve children. Seven lesions were classified as previously recognized entities: vascular malformations (four), papillary endothelial hyperplasia (two), and pyogenic granuloma (lobular capillary hemangioma) (one). Read More

    The utility of GLUT1 as a diagnostic marker in cutaneous vascular anomalies: A review of literature and recommendations for daily practice.
    Pathol Res Pract 2017 Jun 27;213(6):591-597. Epub 2017 Apr 27.
    Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands. Electronic address:
    Objective: To assess the utility of GLUT1 as an immunohistochemical marker in the diagnostics of cutaneous vascular anomalies.

    Methods: A systematic literature search was conducted for studies on GLUT1 staining patterns in cutaneous vascular lesions. Data was grouped according to the latest ISSVA classification for vascular anomalies. Read More

    An update of 77 cases diagnosed as oral hemangiomas based on GLUT-1 positivity.
    Exp Mol Pathol 2017 May 22;103(1):9-13. Epub 2017 May 22.
    Postgraduate Program, Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
    Objectives: To evaluate cases diagnosed as "oral hemangiomas" based on the immunohistochemical expression of human glucose transporter protein (GLUT-1) and on histopathological features, and to investigate whether the classification proposed by the ISSVA was used correctly to classify these lesions.

    Material And Methods: All cases stored in the archives of an Oral Pathology Service and diagnosed as "oral hemangiomas" were reviewed. Seventy-seven cases were analyzed regarding the expression of GLUT-1. Read More

    Interdisciplinary Management of Head and Neck Vascular Anomalies: Clinical Presentation, Diagnostic Findings and Minimalinvasive Therapies.
    Eur J Radiol Open 2017 14;4:63-68. Epub 2017 May 14.
    Department of Otorhinolaryngology and Head and Neck Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
    Objectives: Vascular anomalies are included in the 30 000 rare diseases worldwide affecting less than 5/10 000 people. Depending on their morphology and biological properties, they can cause varied disorders with organ involvement. Almost 60% of vascular anomalies have a predilection for the head and neck region in children. Read More

    Infantile Periocular Hemangioma.
    J Ophthalmic Vis Res 2017 Apr-Jun;12(2):205-211
    Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, Florida, USA.
    Infantile periocular hemangiomas (IPH) are common benign vascular tumors that present early in childhood. They typically show a rapid nonlinear growth pattern a few weeks after birth during a proliferative phase, then continue with an involution phase and may result in serious ocular or systemic complications. Theses tumors may present in a range of small isolated lesions to multiple, diffuse involvements. Read More

    Urinary Excretion of MicroRNA-126 Is a Biomarker for Hemangioma Proliferation.
    Plast Reconstr Surg 2017 Jun;139(6):1277e-1284e
    Columbus, Ohio From the Department of Plastic Surgery, the Department of Biomedical Informatics, Center for Biostatistics, the Department of Surgery, and the Divisions of Vascular Surgery and General Surgery, The Ohio State University; and the Department of Pediatrics, the Hemangioma and Vascular Malformation Clinic, and the Department of Pediatrics, Division of Dermatology, Nationwide Children's Hospital.
    Background: Hemangiomas are unique endothelial cell tumors that involute spontaneously, which makes interpreting their response to therapies difficult. The objective of this work was to identify a potential biomarker in the urine of children with infantile hemangiomas that would facilitate testing new therapies.

    Methods: A prospective longitudinal study in children with hemangiomas and age-matched healthy controls was performed to determine whether microRNA-126, which is highly abundant in fetal endothelial cells, was more abundant in the urine of affected children. Read More

    PARAFOVEAL MICROVASCULAR FEATURES ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN EYES WITH CIRCUMSCRIBED CHOROIDAL HEMANGIOMA.
    Retina 2017 May 19. Epub 2017 May 19.
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
    Purpose: To evaluate parafoveal microvasculature in eyes with circumscribed choroidal hemangioma using optical coherence tomography angiography.

    Methods: Fourteen eyes with unilateral circumscribed choroidal hemangioma were imaged using OCT for central macular thickness and optical coherence tomography angiography for superficial and deep foveal avascular zone area, and superficial and deep capillary density (CD), comparing affected and paired fellow eyes.

    Results: Mean patient age was 53 years, and mean visual acuity was 20/60 in the involved eye and 20/25 in the fellow eye. Read More

    Detection of p53 and Bcl-2 expression in cutaneous hemangioma through the quantum dot technique.
    Oncol Lett 2017 May 13;13(5):2937-2944. Epub 2017 Mar 13.
    Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China.
    Hemangioma is one of the most common types of infantile vascular benign tumor. The aim of the present study was to investigate the role of B-cell lymphoma 2 (Bcl-2) and tumor protein p53 (p53) in the proliferation and apoptosis of hemangioma cells. A total of 38 paraffin-embedded hemangioma specimens (16 males and 22 females) and another 5 paraffin-embedded healthy surrounding tissue samples, collected between January 2007 and December 2010, were obtained from the Department of Pathology at Renmin Hospital of Wuhan University (Wuhan, China). Read More

    Management of a Life Threatening Bleeding Following Extraction of Deciduous Second Molar Related to a Capillary Haemangioma.
    Craniomaxillofac Trauma Reconstr 2017 Jun 16;10(2):166-170. Epub 2017 Mar 16.
    Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
    Various forms of vascular lesion affect the head and neck region. The head and neck vascular lesions are classified into neoplasms and malformations. Neoplasm presents either as hemangioma or lymphangioma; neoplasm usually presents in young age compared with vascular malformation. Read More

    Clinical case series of pediatric hepatic angiosarcoma.
    Pediatr Blood Cancer 2017 May 18. Epub 2017 May 18.
    Division of Hematology/Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
    Hepatic angiosarcoma is a rare, aggressive, malignant neoplasm with fewer than 50 cases reported in children. Prognosis is poor, with a minority surviving beyond 2 years after diagnosis. We report eight cases of pediatric hepatic angiosarcoma, diagnosed at a mean age of 3 years. Read More

    Arrested Development: Infantile Hemangioma and the Stem Cell Teratogenic Hypothesis.
    Lymphat Res Biol 2017 Jun 18;15(2):153-165. Epub 2017 May 18.
    4 Department of Medicine, New York University School of Medicine , New York, New York.
    Background: Early-life programming is defined by the adaptive changes made by the fetus in response to an adverse in utero environment. Infantile hemangioma (IH), a vascular anomaly, is the most common tumor of infancy. Here we take IH as the tumor model to propose the stem cell teratogenic hypothesis of tumorigenesis and the potential involvement of the immune system. Read More

    Use of propranolol in a remote region of rural Guatemala to treat a large facial infantile haemangioma.
    BMJ Case Rep 2017 May 16;2017. Epub 2017 May 16.
    Division of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, USA.
    We present a female infant with a right-sided facial and neck haemangioma, from a remote, resource-poor community in rural Guatemala. She received first-line treatment, propranolol, with marked reduction in tumour size and erythema. Treatment was stopped after 35 weeks due to recurrent diarrhoea and sustained weight loss. Read More

    Propranolol therapy for infantile hemangioma: our experience.
    Drug Des Devel Ther 2017 8;11:1401-1408. Epub 2017 May 8.
    Department of Oral-Maxillary Head and Neck, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai.
    Objective: Hemangiomas are the most common benign vascular tumors of infancy. Although most infantile hemangiomas (IHs) have the ability to involute spontaneously after initial proliferation and resolve without consequence, intervention is required in a subset of IHs, which develop complications resulting in ulceration, bleeding, or aesthetic deformity. The primary treatment for this subset of IHs is pharmacological intervention, and propranolol has become the new first-line treatment for complicated hemangiomas. Read More

    Cardiac hemangioma caused ventricular arrhythmia: A rare case and literature review.
    J Electrocardiol 2017 May 3. Epub 2017 May 3.
    Department of Cardiovascular Ultrasound, First Hospital of China Medical University, Shenyang, Liaoning, China. Electronic address:
    Cardiac hemangioma is a rare primary cardiac tumor. We reported the case of patient with left ventricular hemangioma who was referred to our hospital complaining of palpitation for one week. 24 h Holter revealed high episode of ventricular arrhythmia. Read More

    Modern Management of Nasal Hemangiomas.
    JAMA Facial Plast Surg 2017 Jul;19(4):327-332
    Hemangioma and Malformation Treatment Center, Charleston, South Carolina.
    Importance: Current treatment approaches for infantile hemangiomas of the nose include observation, pharmacologic agents, surgery, and/or laser therapy. Because of the known functional, social, and cosmetic effect of nasal deformities, obtaining the best possible result is critical. Optimal timing, type, duration, and extent of therapy remain unclear. Read More

    Scalp Infantile Hemangioma Complicated by Life-Threatening Bleeding.
    Pediatr Dermatol 2017 Jul 10;34(4):473-475. Epub 2017 May 10.
    Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
    We report on an 8-month-old girl with an ulcerated occipital infantile hemangioma resulting in significant hemorrhage. The hemangioma responded rapidly to systemic propranolol and prednisolone, and we believe that describing her atypical clinical course would be helpful for others managing complicated scalp hemangiomas. Read More

    [Diagnosis and treatment of the tumors of the parotid region in Pediatrics: cohort].
    Cir Pediatr 2016 Oct 10;29(4):135-141. Epub 2016 Oct 10.
    Servicio de Cirugía Pediátrica. Hospital Italiano de Buenos Aires. Buenos Aires, Argentina.
    Introduction: Parotid tumors are rare in children and usually have multiple differential diagnoses that require different diagnostic and treatment methods.

    Material And Methods: Retrospective cohort study of all consecutive pediatric patients with parotid tumors that were treated in Pediatric Surgery Service of Hospital Italiano de Buenos Aires.

    Results: Twenty-two patients with parotid tumors were included and 72% (n=16) were female patients. Read More

    Temperature Instability in an Infant Treated with Propranolol for Infantile Hemangioma.
    J Pediatr Pharmacol Ther 2017 Mar-Apr;22(2):124-127
    Infantile hemangiomas are prevalent in the first few months of life and can be associated with risks of scarring, blindness, ulcerations, and airway obstruction depending on the location of lesions. Options for therapy include surgery, laser therapy, or medications. Propranolol is the only US Food and Drug Administration-approved medication option. Read More

    Capillary Hemangioma of the Tympanic Membrane and External Auditory Canal.
    J Craniofac Surg 2017 May;28(3):e231-e232
    Department of Otolaryngology-Head and Neck Surgery, Kosin University College of Medicine, Busan, Korea.
    Hemangiomas are very common tumors characterized by large numbers of vessels filled with blood. Capillary hemangioma is the most common type of hemangioma, whereas capillary hemangiomas of the tympanic membrane and external auditory canal are extremely rare vascular tumors. The authors present capillary hemangioma of the tympanic membrane and external auditory canal in a 54-year-old woman with right-sided aural fullness for 3 months. Read More

    Successful Treatment of Infantile Hemangiomas With Propranolol in Low-Birth-Weight Infants.
    J Craniofac Surg 2017 May;28(3):789-793
    *Department of Plastic and Reconstructive Surgery, Juntendo University School of Medicine, Tokyo †Department of Plastic and Reconstructive Surgery, Juntendo University Urayasu Hospital, Chiba ‡Department of Plastic and Reconstructive Surgery, Juntendo University Shizuoka Hospital, Shizuoka, Japan.
    Background: Infantile hemangioma (IH) is a benign neoplasm that causes scarring and cosmetic problems after spontaneous regression. Therefore, aggressive treatments such as laser irradiation and corticosteroid have been used; however, recently, the effect of propranolol has been widely noticed. In this study, the authors applied propranolol to low-birth-weight infants with IHs and evaluated its effect. Read More

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