219 results match your criteria Indoor Aeroallergens


Latex aeroallergen pollution in the operating theatre: should latex allergic patients be scheduled first?

Br J Anaesth 2021 08 26;127(2):e46-e48. Epub 2021 May 26.

Department of Anaesthesia and Critical Care, Strasbourg University Hospital, Strasbourg, France. Electronic address:

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Indoor pet allergen exposures modify the effects of chemical air pollutants on respiratory symptoms.

Int J Tuberc Lung Dis 2021 05;25(5):350-357

Épidémiologie des maladies Allergiques et Respiratoires, Institut Pierre Louis d´Épidémiologie et de Santé Publique, Sorbonne University and Institut national de la santé et de la recherche médicale, Saint Antoine Medical School, Paris, France.

Indoor volatile organic compound (VOC) levels, which are generally correlated with each other, may have an additive or synergistic effect on health. VOC synergy with allergens is a suspected mechanism affecting respiration. To determine the effect of exposure to interactions between VOCs and allergens on respiratory symptoms in individuals aged ≥15 years. Read More

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Dog Ownership in Early Life Increased the Risk of Nonatopic Asthma in Children.

Int Arch Allergy Immunol 2021 May 6:1-9. Epub 2021 May 6.

Department of Pediatrics, Childhood Asthma Atopy Center, Humidifier Disinfectant Health Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Background: It is still debatable whether dog ownership during early childhood is a risk factor for the development of allergic diseases.

Objective: We investigated the association of dog ownership in early life with sensitization and asthma in childhood.

Methods: Data from the Cohort for Childhood Origin of Asthma and Allergic diseases were used to investigate the association between dog ownership at any time from pregnancy to 1 year of age and sensitization to aeroallergens at 3 and 7 years old, bronchial hyperresponsiveness (BHR), and asthma at 7 years old. Read More

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The Influence of Indoor Environmental Factors on the Prevalence of House Dust Mites as Aeroallergens in Bandar Abbas Student Dormitories, South of Iran, 2019.

J Med Entomol 2021 Jul;58(4):1865-1873

Social Determinants in Health Promotion Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

This study was conducted to determine the influence of environmental factors on the prevalence of house dust mites in student dormitories of Bandar Abbas city. In this study, 64 dust samples were collected from seven randomly selected dormitories located in various areas of the Bandar Abbas. The collected mites were isolated and mounted in Hoyer's medium and identified using a morphological key. Read More

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A national cross-sectional study of exposure to outdoor nitrogen dioxide and aeroallergen sensitization in Australian children aged 7-11 years.

Environ Pollut 2021 Feb 16;271:116330. Epub 2020 Dec 16.

Faculty of Medicine, School of Public Health, The University of Queensland, Herston, QLD, 4006, Australia; Centre for Air Pollution, Energy and Health Research, Glebe, NSW, 2037, Australia. Electronic address:

The prevalence of allergic diseases in Australian children is high, but few studies have assessed the potential role of outdoor air pollution in allergic sensitization. We investigated the association between outdoor air pollution and the prevalence of aeroallergen sensitization in a national cross-sectional study of Australian children aged 7-11 years. Children were recruited from 55 participating schools in 12 Australian cities during 2007-2008. Read More

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February 2021

"Effects of Tobacco Smoke on Aeroallergen Sensitization and Clinical Severity among University Students and Staff with Allergic Rhinitis".

J Environ Public Health 2020 8;2020:1692930. Epub 2020 Oct 8.

Department of Social Medicine, Walailak University Hospital, Nakhon Si Thammarat 80160, Thailand.

Allergic diseases, affecting a variety of organs, have continuously increased both in developed and developing countries. Tobacco smoke exposure increases prevalence of allergic rhinitis (AR) and may affect allergic sensitization. This study was designed to compare indoor-aeroallergen sensitization between those not exposed and exposed to tobacco smoke in university students and staff with allergic rhinitis. Read More

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December 2020

Impact of indoor air pollution in nursery and primary schools on childhood asthma.

Sci Total Environ 2020 Nov 18;745:140982. Epub 2020 Jul 18.

LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal. Electronic address:

Poor indoor air quality in scholar environments have been frequently reported, but its impact on respiratory health in schoolchildren has not been sufficiently explored. Thus, this study aimed to evaluate the associations between children's exposure to indoor air pollution (IAP) in nursery and primary schools and childhood asthma. Multivariate models (independent and multipollutant) quantified the associations of children's exposure with asthma-related health outcomes: reported active wheezing, reported and diagnosed asthma, and lung function (reduced FEV/FVC and reduced FEV). Read More

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November 2020

An Overview of Rising CO₂ and Climatic Change on Aeroallergens and Allergic Diseases.

Authors:
Lewis H Ziska

Allergy Asthma Immunol Res 2020 Sep;12(5):771-782

Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.

There are a number of implications of climate change in regard to human health. Among these, the role of rising carbon dioxide (CO₂) and temperature in aeroallergen exposure and associated changes in the start, duration and intensity of the pollen season, and associated consequences in aeroallergens and allergic disease are a primary concern. This review is intended to provide a synopsis of CO₂ and climate factors associated with likely changes in aeroallergen biology (indoor and outdoor), including changes in the demography of flowering plants, pollen seasonality, aeroallergen production, and potential biotic and abiotic interactions. Read More

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September 2020

The Indoor Environment and Childhood Asthma.

Curr Allergy Asthma Rep 2020 06 16;20(9):43. Epub 2020 Jun 16.

Boston Children's Hospital, Division of Immunology, Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA.

Purpose Of Review: Sensitization and exposure to triggers in the indoor environment, including aeroallergens, indoor air pollution, and environmental tobacco smoke, have a significant role in asthma development and morbidity. This review discusses indoor environmental exposures and their effect on children with asthma as well as environmental interventions and their role in improving asthma morbidity.

Recent Findings: Recent research has emphasized the role of aeroallergen sensitization and exposure in asthma morbidity and the importance of the school indoor environment. Read More

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Airborne food and aeroallergens levels in healthcare settings. An unaccounted but potentially relevant source of exposure?

J Investig Allergol Clin Immunol 2020 Jun 5. Epub 2020 Jun 5.

Serviço de Imunologia Básica e Clínica, Departamento de Patologia, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.

Background And Objective: Exposure to airborne allergens of biological origin associates with the development and exacerbation of allergic asthma and rhinitis. Assessment of allergens exposure in healthcare facilities may contribute to monitor hygiene and survey specific allergens which may cause symptoms in sensitized subjects. Objective: To assess concentration of indoor and airborne food allergens across different healthcare settings. Read More

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Identification of the major allergenic proteins from silkworm moth (Bombyx mori) involved in respiratory allergic diseases.

Allergol Immunopathol (Madr) 2020 Nov - Dec;48(6):597-602. Epub 2020 Apr 10.

Programa de Pós-graduação em Saúde da Criança e do Adolescente, Universidade Federal do Paraná, Brazil.

Introduction And Objectives: Moths are a significant source of indoor and outdoor aeroallergens. High prevalence of IgE-mediated sensitization was demonstrated in a group of patients with allergic respiratory diseases. There are no studies on adult stage of these moth species allergens involved in allergic respiratory reactions - the aim of this study. Read More

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Aeroallergen sensitization in Lebanese asthmatic children: the results of a cohort national study.

Environ Sci Pollut Res Int 2020 Feb 19;27(5):5597-5605. Epub 2019 Dec 19.

Faculty of Medicine and Medical Sciences, Holy Spirit University of Kaslik (USEK), Jounieh, Lebanon.

Atopic asthma is characterized by the presence of sensitization to common aeroallergens, which tends to have a worse prognosis than non-atopic asthma. The objectives were to determine the prevalence of aeroallergens sensitization in the Lebanese pediatric asthmatic population and determine the relationship between allergens sensitization (indoor and outdoor) and age, area of residence and altitude. A sample, consisting of 919 asthmatic children (aged 1 to 18 years, from 2010 until 2017), underwent skin prick testing (SPT) with 21 common allergens: 5 grasses (cocksfoot, sweet vernal-grass, rye-grass, meadow grass, timothy), Parietaria, olive, Dermatophagoides pteronyssinus and Dermatophagoides farina (DP-DF), dog and cat dander, Alternaria longipens, Aspergillus fumigatus and nidulans, Cupressaceae, pine, German cockroach, and 4 cereals (oat, wheat, barley, maize). Read More

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February 2020

Effects of indoor particulate matter exposure on daily asthma control.

Ann Allergy Asthma Immunol 2019 10 26;123(4):375-380.e3. Epub 2019 Jul 26.

National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom; Department of Respiratory Medicine, Nottingham University Hospitals National Health Service Trust, Nottingham, United Kingdom. Electronic address:

Background: Household dust often contains aeroallergens, such as the house dust mite antigen Der p 1. It has been proposed that overnight exposure to particulate matter from bedding and other sources may be an important driver of atopic asthma. Whether variability in overnight particulate matter exposure is a significant determinant of asthma control is unknown. Read More

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October 2019

Human glutathione-S-transferase pi potentiates the cysteine-protease activity of the Der p 1 allergen from house dust mite through a cysteine redox mechanism.

Redox Biol 2019 09 11;26:101256. Epub 2019 Jun 11.

Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense, Madrid, Spain. Electronic address:

Environmental proteases have been widely associated to the pathogenesis of allergic disorders. Der p 1, a cysteine-protease from house dust mite (HDM) Dermatophagoides pteronyssinus, constitutes one of the most clinically relevant indoor aeroallergens worldwide. Der p 1 protease activity depends on the redox status of its catalytic cysteine residue, which has to be in the reduced state to be active. Read More

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September 2019

Impact of weather and climate change with indoor and outdoor air quality in asthma: A Work Group Report of the AAAAI Environmental Exposure and Respiratory Health Committee.

J Allergy Clin Immunol 2019 05 28;143(5):1702-1710. Epub 2019 Feb 28.

University of California Los Angeles, David Geffen School of Medicine and California NanoSystems Institute, Los Angeles, Calif.

Weather and climate change are constant and ever-changing processes that affect allergy and asthma. The purpose of this report is to provide information since the last climate change review with a focus on asthmatic disease. PubMed and Internet searches for topics included climate and weather change, air pollution, particulates, greenhouse gasses, traffic, insect habitat, and mitigation in addition to references contributed by the individual authors. Read More

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Perceived Versus Actual Aeroallergen Sensitization in Urban Children.

J Allergy Clin Immunol Pract 2019 May - Jun;7(5):1591-1598.e4. Epub 2019 Jan 14.

Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY; Mindich Child Health and Development Institute and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

Background: Individuals often report allergy to specific aeroallergens, but allergy testing can reveal disparate sensitization.

Objective: To characterize the agreement between perceived and actual sensitization to individual aeroallergens in an urban pediatric population.

Methods: A total of 253 children were enrolled from pediatric clinics in New York, NY. Read More

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Specific IgE Assay for Respiratory Allergens in Patients with Atopy in Ahvaz, Iran.

Iran J Immunol 2018 Dec;15(4):294-301

Specialized Immunology Laboratory of Dr. Shahrooei, Sina Medical Complex, Ahvaz.

Background: The frequency of sensitization to respiratory allergens is different in various geographical regions.

Objective: To determine the level of specific IgE to respiratory allergens in patients with atopy in Ahvaz, Iran.

Methods: In this retrospective cross-sectional study, the total and specific IgE data were recorded for 408 patients with allergic rhinitis and asthma referred to allergy diagnostic laboratory in Ahvaz from 2014 to 2017. Read More

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December 2018

Aeroallergen Exposure and Spread in the Modern Era.

J Allergy Clin Immunol Pract 2018 Nov - Dec;6(6):1835-1842

Division of Allergy & Immunology, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio. Electronic address:

Since the initial discovery of aeroallergens in the 20th century, our understanding of their properties including sources and factors influencing their spread continues to expand. Both habits of daily living and the presence of environmental factors such as exposure to animals or pollution can influence susceptibility to atopic disease. Because relevant allergens may vary in individuals and communities, it is necessary to understand the physical properties of environmental aeroallergens that are associated with clinical disease to explain symptoms and to implement successful integrated interventions. Read More

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November 2019

Aeroallergens Exacerbate Infection.

J Immunol 2018 12 22;201(11):3352-3361. Epub 2018 Oct 22.

Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, OH 45267; and

Allergens such as house dust mites (HDM) and papain induce strong Th2 responses, including elevated IL-4, IL-5, and IL-13 and marked eosinophilia in the airways. is a dimorphic fungal pathogen that induces a strong Th1 response marked by IFN-γ and TNF-α production, leading to rapid clearance in nonimmunocompromised hosts. Th1 responses are generally dominant and overwhelm the Th2 response when stimuli for both are present, although there are instances when Th2 stimuli downregulate a Th1 response. Read More

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December 2018

Skin Prick Test Reactivity to Common Aeroallergens among Allergic Rhinitis Patients.

J Coll Physicians Surg Pak 2018 Oct;28(10):766-771

Department of Computer Science, College of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Objective: To identify the common aeroallergens causing allergy symptoms among the allergic rhinitis patients.

Study Design: Cross-sectional study.

Place And Duration Of Study: Department of Immunology, Armed Forces Institute of Pathology (AFIP), Rawalpindi, from January to July 2016. Read More

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October 2018

Aeroallergen sensitization and associated comorbid diseases of an adult Filipino population with allergic rhinitis.

Asia Pac Allergy 2018 Jul 17;8(3):e25. Epub 2018 Jul 17.

Department of Otolaryngology-Head & Neck Surgery, St. Luke's Medical Center-Quezon City, Quezon City 1112, the Philippines.

Background: There is a large global variation in sensitization patterns to aeroallergens due to differences in climate, urbanization, and lifestyle. Knowledge of the most common inhalant allergens is important for appropriate prevention and management of allergic rhinitis (AR).

Objective: This study aims to provide data on aeroallergen sensitization patterns and associated comorbid diseases of adult Filipinos with AR. Read More

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High burden of atopy in immigrant families in substandard apartments in Sweden - on the contribution of bad housing to poor health in vulnerable populations.

World Allergy Organ J 2018 15;11(1). Epub 2018 May 15.

1Division of Occupational and Environmental Medicine, Medical Faculty, Lund University, 22185 Lund, Sweden.

Background: Atopic disorders are a global concern. Studies in migrant populations can illuminate the interplay of genetic and environmental factors. Exposures related to bad housing (indoor dampness, mould growth, crowding etc. Read More

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Airborne protein concentration: a key metric for type 1 allergy risk assessment-in home measurement challenges and considerations.

Clin Transl Allergy 2018 26;8:10. Epub 2018 Mar 26.

SEAC Unilever Colworth, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ UK.

Background: Exposure to airborne proteins can be associated with the development of immediate, IgE-mediated respiratory allergies, with genetic, epigenetic and environmental factors also playing a role in determining the likelihood that sensitisation will be induced. The main objective of this study was to determine whether airborne concentrations of selected common aeroallergens could be quantified in the air of homes using easily deployable, commercially available equipment and analytical methods, at low levels relevant to risk assessment of the potential to develop respiratory allergies. Additionally, air and dust sampling were compared and the influence of factors such as different filter types on allergen quantification explored. Read More

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External exposome and allergic respiratory and skin diseases.

J Allergy Clin Immunol 2018 03;141(3):846-857

Sorbonne Université, INSERM, Pierre Louis Institute of Epidemiology and Public Health, Epidemiology of Allergic and Respiratory Diseases Department (EPAR), Saint-Antoine Medical School, Paris, France. Electronic address:

Allergies are complex diseases that result from interactions between multiple genetic and environmental factors. However, the increase in allergies observed in the past decades is explained exclusively by environmental changes occurring in the same period. Presently, the exposome, the totality of specific and nonspecific external environmental exposures (external exposome) to which a subject is exposed from preconception onward and their consequences at the organ and cell levels (internal exposome), is being considered to explain the inception, development, and exacerbations of allergic diseases. Read More

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Respiratory comorbidity in South African children with atopic dermatitis.

S Afr Med J 2017 Sep 22;107(10):904-909. Epub 2017 Sep 22.

Division of Allergology, Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Cape Town, and Faculty of Health Sciences, University of Cape Town, South Africa.

Background: Atopic dermatitis (AD) is an early and important step in the propagation of the allergic march, enhancing food and respiratory allergies via epicutaneous sensitisation to allergens.

Objectives: To determine the prevalence and patterns of aeroallergen sensitisation, asthma and allergic rhinitis in South African (SA) children with AD.

Methods: This was a prospective, observational study in a paediatric university hospital in Cape Town, SA. Read More

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September 2017

Allergy and immunology in Africa: Challenges and unmet needs.

J Allergy Clin Immunol 2017 Nov 27;140(5):1240-1243. Epub 2017 Sep 27.

Pediatric Allergy and Immunology Unit, Children's Hospital, Ain Shams University, Cairo, Egypt.

The tremendous increase in allergy in the African continent cannot simply be explained by the change in public hygiene. There are many "prehygiene" communities with sewage-contaminated water supplies, helminth infestations, bare footedness, and poor housing, and still there is a high prevalence of allergic disease. Africans can be exposed to many risk factors facilitating severe asthma and wheezing, including airborne viruses, smoke, indoor dampness, cockroaches, and poor access to health care. Read More

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November 2017

Determination of the Most Common Indoor and Outdoor Allergens in 602 Patients with Allergic Symptoms Using Specific IgE Local Panel.

Iran J Allergy Asthma Immunol 2017 Aug;16(4):298-306

Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran AND Department of Immunology, Children Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

Aeroallergens play an important role in developing allergic diseases. The aim of this study was to determine the outdoor and indoor sensitization using a specific regional panel of aeroallergens in allergic patients. All patients with allergic symptoms referred to Immunology, Asthma and Allergy Research Institute (IAARI) in Tehran, Iran from December 2010 to July 2013 entered this cross sectional study. Read More

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Indoor visible mold and mold odor are associated with new-onset childhood wheeze in a dose-dependent manner.

Indoor Air 2018 Jan 11;28(1):6-15. Epub 2017 Sep 11.

He Kainga Oranga/Housing and Health Research Group, Department of Public Health, University of Otago, Wellington, New Zealand.

Evidence is accumulating that indoor dampness and mold are associated with the development of asthma. The underlying mechanisms remain unknown. New Zealand has high rates of both asthma and indoor mold and is ideally placed to investigate this. Read More

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January 2018

Sensitization to Common Aeroallergens in Asthmatic Children in the Eastern Region of Saudi Arabia.

Authors:
Suzan A AlKhater

Saudi J Med Med Sci 2017 May-Aug;5(2):136-141. Epub 2017 Apr 20.

Department of Pediatrics, College of Medicine, King Fahd Hospital of the University, University of Dammam, Dammam, Saudi Arabia.

Background: Allergic disorders, particularly bronchial asthma, are one of the most common chronic childhood diseases. Bronchial asthma is more prevalent among children of the Eastern Province of Saudi Arabia compared with the other provinces. Environmental factors play major roles in the disease pathogenesis in genetically predisposed hosts. Read More

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