228 results match your criteria Indoor Aeroallergens


The Effect of the COVID-19 Pandemic Lockdown on Symptom Severity in School Children with House Dust Mite Sensitized Allergic Rhinitis.

Rev Fr Allergol (2009) 2022 Jul 18. Epub 2022 Jul 18.

Health Science University, Dr. Behcet Uz Child Disease and Pediatric Surgery Training and Research Hospital, Department of Pediatrics, Division of Allergy and Immunology, Turkey.

Study Objective: The lockdown imposed on children due to the COVID-19 pandemic and their inability to attend school increased their exposure to indoor allergens by causing them to spend more time indoors. In this study, the aim was to reveal the effect of the pandemic and increased exposure to indoor aeroallergens on the symptom severity of school-age children with house dust mite-sensitized allergic rhinitis (AR).

Patients And Methods: Patients between the ages of 6-18-years old, who were followed-up with the diagnosis of perennial AR sensitized to only mites were questioned about their sinonasal symptoms. Read More

View Article and Full-Text PDF

Environmental inequality: Air pollution and asthma in children.

Pediatr Allergy Immunol 2022 06;33(6)

EPIUnit, Institute of Public Health, University of Porto, Porto, Portugal.

Introduction: Whether you benefit from high-quality urban environments, such as those rich in green and blue spaces, that may offer benefits to allergic and respiratory health depends on where you live and work. Environmental inequality, therefore, results from the unequal distribution of the risks and benefits that stem from interactions with our environment.

Methods: Within this perspective, this article reviews the evidence for an association between air pollution caused by industrial activities, traffic, disinfection-by-products, and tobacco/e-cigarettes, and asthma in children. Read More

View Article and Full-Text PDF

Prevalence of Sensitization to Aeroallergens in Greater Beijing Region Children With Respiratory Allergy.

Front Pediatr 2022 19;10:848357. Epub 2022 May 19.

Department of Allergy, Children's Hospital of Capital Institute of Pediatrics, Beijing, China.

Objective: To evaluate the prevalence and distribution of sensitization to aeroallergens in children with atopic diseases.

Methods: We conducted skin prick test on 9,527 pediatric patients (aged 0-17 years) with atopic diseases in allergy department of Children's Hospital affiliated with the Capital Institute of Pediatrics. Positive rates of aeroallergens were compared among the different groups. Read More

View Article and Full-Text PDF

KOREAN AEROALLERGEN SENSITIZATION STATUS FROM 2018-2021.

Clin Exp Otorhinolaryngol 2022 May 26. Epub 2022 May 26.

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Konkuk University, Seoul, Korea.

Objectives: To date, studies on the aeroallergen sensitization status of Koreans based on large-scale data are lacking.

Methods: We analyzed the data for 368,156 multiple allergosorbent tests (MAST) collected by a domestic medical diagnosis company from 3,735 hospitals nationwide from 2018 to 2021. We additionally collected sex, age, and regional data. Read More

View Article and Full-Text PDF

Pattern of Aeroallergen Sensitization and Quality of Life in Adult Thai Patients With Allergic Rhinitis.

Front Allergy 2021 15;2:695055. Epub 2021 Nov 15.

Division of Rhinology and Allergy, Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

The prevalence of allergic rhinitis (AR) is steadily rising in the Thai population, causing a major impact on the quality of life (QoL). Enhancing knowledge on common aeroallergens in the local setting helps in the appropriate prevention and management of AR. In this study, the demographic characteristics, clinical data, aeroallergen sensitization pattern, allergic symptoms, visual analog scale (VAS) score, and QoL are described. Read More

View Article and Full-Text PDF
November 2021

Allergen Management in Children with Type 2-High Asthma.

J Asthma Allergy 2022 29;15:381-394. Epub 2022 Mar 29.

Department of Pediatrics, Section of Allergy and Clinical Immunology, University of Manitoba, Winnipeg, Canada.

Children exposed to various indoor and outdoor allergens are placed at an increased risk of developing asthma in later life, with sensitization in these individuals being a strong predictor of disease morbidity. In addition, aeroallergen exposure influences asthma outcomes through an interplay with adverse determinants of health. The goal of this review is to provide an introductory overview of factors related to aeroallergen exposure in type 2-high childhood asthma. Read More

View Article and Full-Text PDF

Hurricane María drives increased indoor proliferation of filamentous fungi in San Juan, Puerto Rico: a two-year culture-based approach.

PeerJ 2022 3;10:e12730. Epub 2022 Mar 3.

School of Architecture, University of Puerto Rico, Río Piedras Campus, San Juan, PR, USA.

Extensive flooding caused by Hurricane María in Puerto Rico (PR) created favorable conditions for indoor growth of filamentous fungi. These conditions represent a public health concern as contamination by environmental fungi is associated with a higher prevalence of inflammatory respiratory conditions. This work compares culturable fungal spore communities present in homes that sustained water damage after Hurricane María to those present in dry, non-flooded homes. Read More

View Article and Full-Text PDF

Effectiveness and safety of oral lactococci-based vaccine encoding triple common allergens to prevent airway allergy in mice.

PLoS One 2021 31;16(12):e0261333. Epub 2021 Dec 31.

Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan.

Allergic airway disease is the most common chronic airway inflammatory disorder in developed countries. House dust mite, cockroach, and mold are the leading allergens in most tropical and subtropical countries, including Taiwan. As allergen avoidance is difficult for patients allergic to these perennial indoor allergens, allergen-specific immunotherapy (ASIT) is the only available allergen-specific and disease-modifying treatment. Read More

View Article and Full-Text PDF
January 2022

Airborne Food Allergen and Aeroallergen Levels in Health Care Settings: An Unaccounted for but Potentially Relevant Source of Exposure?

J Investig Allergol Clin Immunol 2021 Oct;31(5):426-432

Serviço de Imunologia Básica e Clínica, Departamento de Patologia, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.

Background And Objective: Exposure to airborne allergens of biological origin is associated with the development and exacerbation of allergic asthma and rhinitis. Assessment of allergen exposure in health care facilities may improve monitoring of hygiene and surveillance of specific allergens that can cause symptoms in sensitized persons. Objective: To assess concentrations of airborne food and aeroallergens in various health care settings in Portugal. Read More

View Article and Full-Text PDF
October 2021

Fungal Spore Richness in School Classrooms is Related to Surrounding Forest in a Season-Dependent Manner.

Microb Ecol 2021 Sep 8. Epub 2021 Sep 8.

Institute of Environmental and Occupational Health Sciences, College of Public Health, National Taiwan University, No.17, Xu-Zhou Rd., Taipei, 100025, Taiwan.

Airborne fungal spores are important aeroallergens that are remarkably diverse in terms of taxonomic richness. Indoor fungal richness is dominated by outdoor fungi and is geographically patterned, but the influence of natural landscape is unclear. We aimed to elucidate the relationship between indoor fungal spore richness and natural landscape by examining the amount of surrounding forest cover. Read More

View Article and Full-Text PDF
September 2021

Latex aeroallergen pollution in the operating theatre: should latex allergic patients be scheduled first?

Br J Anaesth 2021 08 26;127(2):e46-e48. Epub 2021 May 26.

Department of Anaesthesia and Critical Care, Strasbourg University Hospital, Strasbourg, France. Electronic address:

View Article and Full-Text PDF

Indoor pet allergen exposures modify the effects of chemical air pollutants on respiratory symptoms.

Int J Tuberc Lung Dis 2021 05;25(5):350-357

Épidémiologie des maladies Allergiques et Respiratoires, Institut Pierre Louis d´Épidémiologie et de Santé Publique, Sorbonne University and Institut national de la santé et de la recherche médicale, Saint Antoine Medical School, Paris, France.

Indoor volatile organic compound (VOC) levels, which are generally correlated with each other, may have an additive or synergistic effect on health. VOC synergy with allergens is a suspected mechanism affecting respiration. To determine the effect of exposure to interactions between VOCs and allergens on respiratory symptoms in individuals aged ≥15 years. Read More

View Article and Full-Text PDF

Dog Ownership in Early Life Increased the Risk of Nonatopic Asthma in Children.

Int Arch Allergy Immunol 2021;182(10):980-988. Epub 2021 May 6.

Department of Pediatrics, Childhood Asthma Atopy Center, Humidifier Disinfectant Health Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Background: It is still debatable whether dog ownership during early childhood is a risk factor for the development of allergic diseases.

Objective: We investigated the association of dog ownership in early life with sensitization and asthma in childhood.

Methods: Data from the Cohort for Childhood Origin of Asthma and Allergic diseases were used to investigate the association between dog ownership at any time from pregnancy to 1 year of age and sensitization to aeroallergens at 3 and 7 years old, bronchial hyperresponsiveness (BHR), and asthma at 7 years old. Read More

View Article and Full-Text PDF
November 2021

The Influence of Indoor Environmental Factors on the Prevalence of House Dust Mites as Aeroallergens in Bandar Abbas Student Dormitories, South of Iran, 2019.

J Med Entomol 2021 07;58(4):1865-1873

Social Determinants in Health Promotion Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

This study was conducted to determine the influence of environmental factors on the prevalence of house dust mites in student dormitories of Bandar Abbas city. In this study, 64 dust samples were collected from seven randomly selected dormitories located in various areas of the Bandar Abbas. The collected mites were isolated and mounted in Hoyer's medium and identified using a morphological key. Read More

View Article and Full-Text PDF

A national cross-sectional study of exposure to outdoor nitrogen dioxide and aeroallergen sensitization in Australian children aged 7-11 years.

Environ Pollut 2021 Feb 16;271:116330. Epub 2020 Dec 16.

Faculty of Medicine, School of Public Health, The University of Queensland, Herston, QLD, 4006, Australia; Centre for Air Pollution, Energy and Health Research, Glebe, NSW, 2037, Australia. Electronic address:

The prevalence of allergic diseases in Australian children is high, but few studies have assessed the potential role of outdoor air pollution in allergic sensitization. We investigated the association between outdoor air pollution and the prevalence of aeroallergen sensitization in a national cross-sectional study of Australian children aged 7-11 years. Children were recruited from 55 participating schools in 12 Australian cities during 2007-2008. Read More

View Article and Full-Text PDF
February 2021

"Effects of Tobacco Smoke on Aeroallergen Sensitization and Clinical Severity among University Students and Staff with Allergic Rhinitis".

J Environ Public Health 2020 8;2020:1692930. Epub 2020 Oct 8.

Department of Social Medicine, Walailak University Hospital, Nakhon Si Thammarat 80160, Thailand.

Allergic diseases, affecting a variety of organs, have continuously increased both in developed and developing countries. Tobacco smoke exposure increases prevalence of allergic rhinitis (AR) and may affect allergic sensitization. This study was designed to compare indoor-aeroallergen sensitization between those not exposed and exposed to tobacco smoke in university students and staff with allergic rhinitis. Read More

View Article and Full-Text PDF
December 2020

Impact of indoor air pollution in nursery and primary schools on childhood asthma.

Sci Total Environ 2020 Nov 18;745:140982. Epub 2020 Jul 18.

LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal. Electronic address:

Poor indoor air quality in scholar environments have been frequently reported, but its impact on respiratory health in schoolchildren has not been sufficiently explored. Thus, this study aimed to evaluate the associations between children's exposure to indoor air pollution (IAP) in nursery and primary schools and childhood asthma. Multivariate models (independent and multipollutant) quantified the associations of children's exposure with asthma-related health outcomes: reported active wheezing, reported and diagnosed asthma, and lung function (reduced FEV/FVC and reduced FEV). Read More

View Article and Full-Text PDF
November 2020

An Overview of Rising CO₂ and Climatic Change on Aeroallergens and Allergic Diseases.

Authors:
Lewis H Ziska

Allergy Asthma Immunol Res 2020 Sep;12(5):771-782

Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.

There are a number of implications of climate change in regard to human health. Among these, the role of rising carbon dioxide (CO₂) and temperature in aeroallergen exposure and associated changes in the start, duration and intensity of the pollen season, and associated consequences in aeroallergens and allergic disease are a primary concern. This review is intended to provide a synopsis of CO₂ and climate factors associated with likely changes in aeroallergen biology (indoor and outdoor), including changes in the demography of flowering plants, pollen seasonality, aeroallergen production, and potential biotic and abiotic interactions. Read More

View Article and Full-Text PDF
September 2020

The Indoor Environment and Childhood Asthma.

Curr Allergy Asthma Rep 2020 06 16;20(9):43. Epub 2020 Jun 16.

Boston Children's Hospital, Division of Immunology, Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA.

Purpose Of Review: Sensitization and exposure to triggers in the indoor environment, including aeroallergens, indoor air pollution, and environmental tobacco smoke, have a significant role in asthma development and morbidity. This review discusses indoor environmental exposures and their effect on children with asthma as well as environmental interventions and their role in improving asthma morbidity.

Recent Findings: Recent research has emphasized the role of aeroallergen sensitization and exposure in asthma morbidity and the importance of the school indoor environment. Read More

View Article and Full-Text PDF

Identification of the major allergenic proteins from silkworm moth (Bombyx mori) involved in respiratory allergic diseases.

Allergol Immunopathol (Madr) 2020 Nov - Dec;48(6):597-602. Epub 2020 Apr 10.

Programa de Pós-graduação em Saúde da Criança e do Adolescente, Universidade Federal do Paraná, Brazil.

Introduction And Objectives: Moths are a significant source of indoor and outdoor aeroallergens. High prevalence of IgE-mediated sensitization was demonstrated in a group of patients with allergic respiratory diseases. There are no studies on adult stage of these moth species allergens involved in allergic respiratory reactions - the aim of this study. Read More

View Article and Full-Text PDF
September 2021

Aeroallergen sensitization in Lebanese asthmatic children: the results of a cohort national study.

Environ Sci Pollut Res Int 2020 Feb 19;27(5):5597-5605. Epub 2019 Dec 19.

Faculty of Medicine and Medical Sciences, Holy Spirit University of Kaslik (USEK), Jounieh, Lebanon.

Atopic asthma is characterized by the presence of sensitization to common aeroallergens, which tends to have a worse prognosis than non-atopic asthma. The objectives were to determine the prevalence of aeroallergens sensitization in the Lebanese pediatric asthmatic population and determine the relationship between allergens sensitization (indoor and outdoor) and age, area of residence and altitude. A sample, consisting of 919 asthmatic children (aged 1 to 18 years, from 2010 until 2017), underwent skin prick testing (SPT) with 21 common allergens: 5 grasses (cocksfoot, sweet vernal-grass, rye-grass, meadow grass, timothy), Parietaria, olive, Dermatophagoides pteronyssinus and Dermatophagoides farina (DP-DF), dog and cat dander, Alternaria longipens, Aspergillus fumigatus and nidulans, Cupressaceae, pine, German cockroach, and 4 cereals (oat, wheat, barley, maize). Read More

View Article and Full-Text PDF
February 2020

Effects of indoor particulate matter exposure on daily asthma control.

Ann Allergy Asthma Immunol 2019 10 26;123(4):375-380.e3. Epub 2019 Jul 26.

National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom; Department of Respiratory Medicine, Nottingham University Hospitals National Health Service Trust, Nottingham, United Kingdom. Electronic address:

Background: Household dust often contains aeroallergens, such as the house dust mite antigen Der p 1. It has been proposed that overnight exposure to particulate matter from bedding and other sources may be an important driver of atopic asthma. Whether variability in overnight particulate matter exposure is a significant determinant of asthma control is unknown. Read More

View Article and Full-Text PDF
October 2019

Human glutathione-S-transferase pi potentiates the cysteine-protease activity of the Der p 1 allergen from house dust mite through a cysteine redox mechanism.

Redox Biol 2019 09 11;26:101256. Epub 2019 Jun 11.

Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense, Madrid, Spain. Electronic address:

Environmental proteases have been widely associated to the pathogenesis of allergic disorders. Der p 1, a cysteine-protease from house dust mite (HDM) Dermatophagoides pteronyssinus, constitutes one of the most clinically relevant indoor aeroallergens worldwide. Der p 1 protease activity depends on the redox status of its catalytic cysteine residue, which has to be in the reduced state to be active. Read More

View Article and Full-Text PDF
September 2019

Impact of weather and climate change with indoor and outdoor air quality in asthma: A Work Group Report of the AAAAI Environmental Exposure and Respiratory Health Committee.

J Allergy Clin Immunol 2019 05 28;143(5):1702-1710. Epub 2019 Feb 28.

University of California Los Angeles, David Geffen School of Medicine and California NanoSystems Institute, Los Angeles, Calif.

Weather and climate change are constant and ever-changing processes that affect allergy and asthma. The purpose of this report is to provide information since the last climate change review with a focus on asthmatic disease. PubMed and Internet searches for topics included climate and weather change, air pollution, particulates, greenhouse gasses, traffic, insect habitat, and mitigation in addition to references contributed by the individual authors. Read More

View Article and Full-Text PDF

Perceived Versus Actual Aeroallergen Sensitization in Urban Children.

J Allergy Clin Immunol Pract 2019 May - Jun;7(5):1591-1598.e4. Epub 2019 Jan 14.

Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY; Mindich Child Health and Development Institute and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

Background: Individuals often report allergy to specific aeroallergens, but allergy testing can reveal disparate sensitization.

Objective: To characterize the agreement between perceived and actual sensitization to individual aeroallergens in an urban pediatric population.

Methods: A total of 253 children were enrolled from pediatric clinics in New York, NY. Read More

View Article and Full-Text PDF

Specific IgE Assay for Respiratory Allergens in Patients with Atopy in Ahvaz, Iran.

Iran J Immunol 2018 Dec;15(4):294-301

Specialized Immunology Laboratory of Dr. Shahrooei, Sina Medical Complex, Ahvaz.

Background: The frequency of sensitization to respiratory allergens is different in various geographical regions.

Objective: To determine the level of specific IgE to respiratory allergens in patients with atopy in Ahvaz, Iran.

Methods: In this retrospective cross-sectional study, the total and specific IgE data were recorded for 408 patients with allergic rhinitis and asthma referred to allergy diagnostic laboratory in Ahvaz from 2014 to 2017. Read More

View Article and Full-Text PDF
December 2018

Aeroallergen Exposure and Spread in the Modern Era.

J Allergy Clin Immunol Pract 2018 Nov - Dec;6(6):1835-1842

Division of Allergy & Immunology, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio. Electronic address:

Since the initial discovery of aeroallergens in the 20th century, our understanding of their properties including sources and factors influencing their spread continues to expand. Both habits of daily living and the presence of environmental factors such as exposure to animals or pollution can influence susceptibility to atopic disease. Because relevant allergens may vary in individuals and communities, it is necessary to understand the physical properties of environmental aeroallergens that are associated with clinical disease to explain symptoms and to implement successful integrated interventions. Read More

View Article and Full-Text PDF
November 2019

Aeroallergens Exacerbate Infection.

J Immunol 2018 12 22;201(11):3352-3361. Epub 2018 Oct 22.

Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, OH 45267; and

Allergens such as house dust mites (HDM) and papain induce strong Th2 responses, including elevated IL-4, IL-5, and IL-13 and marked eosinophilia in the airways. is a dimorphic fungal pathogen that induces a strong Th1 response marked by IFN-γ and TNF-α production, leading to rapid clearance in nonimmunocompromised hosts. Th1 responses are generally dominant and overwhelm the Th2 response when stimuli for both are present, although there are instances when Th2 stimuli downregulate a Th1 response. Read More

View Article and Full-Text PDF
December 2018

Skin Prick Test Reactivity to Common Aeroallergens among Allergic Rhinitis Patients.

J Coll Physicians Surg Pak 2018 Oct;28(10):766-771

Department of Computer Science, College of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Objective: To identify the common aeroallergens causing allergy symptoms among the allergic rhinitis patients.

Study Design: Cross-sectional study.

Place And Duration Of Study: Department of Immunology, Armed Forces Institute of Pathology (AFIP), Rawalpindi, from January to July 2016. Read More

View Article and Full-Text PDF
October 2018