263,066 results match your criteria Indian journal of dermatology venereology and leprology[Journal]


C9orf72 repeat expansions in South Africans with amyotrophic lateral sclerosis.

J Neurol Sci 2019 Apr 17;401:51-54. Epub 2019 Apr 17.

Neurology research group, Department of Medicine, University of Cape Town, Cape Town, South Africa; Division of Neurology, Department of Medicine, University of Cape Town, Cape Town, South Africa. Electronic address:

The hexanucleotide repeat expansion in the C9orf72 gene is the most common genetic variant found in individuals with sporadic amyotrophic lateral sclerosis (ALS), occurring at a frequency of between 7 and 11% in cohorts of European ancestry. While limited data suggest that C9-expansions (>30 repeats) are less frequent in African-Americans with ALS, there is no data on the frequency of C9-expansions among ALS subjects residing in Africa. We therefore investigated the frequency of this expansion mutation (using repeat-primed PCR) in a cohort of 143 South Africans (SA) with ALS. Read More

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http://dx.doi.org/10.1016/j.jns.2019.04.026DOI Listing

Evaluating the performance of sequence encoding schemes and machine learning methods for splice sites recognition.

Gene 2019 Apr 19. Epub 2019 Apr 19.

ICAR-Indian Agricultural Statistics Research Institute, New Delhi 110012, India. Electronic address:

Identification of splice sites is imperative for prediction of gene structure. Machine learning-based approaches (MLAs) have been reported to be more successful than the rule-based methods for identification of splice sites. However, the strings of alphabets should be transformed into numeric features through sequence encoding before using them as input in MLAs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03781119193040
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http://dx.doi.org/10.1016/j.gene.2019.04.047DOI Listing
April 2019
1 Read

Genetic status of indigenous poultry (red jungle fowl) from India.

Gene 2019 Apr 19. Epub 2019 Apr 19.

Department of Biotechnology, Assam University, Silchar, Assam Pin-788011, India; University of Kalyani, Nadia, West Bengal Pin-741235, India. Electronic address:

The global biodiversity of domesticated red jungle fowl (Gallus gallus) is gradually eroding by replacement with commercial poultry breeds and results loss of valuable genetic and physical traits like resistance to disease, extreme environment, etc. posing a threat to the poultry genetic resources. Very fewer reports exist on Indian poultry diversity, especially native chicken of India. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03781119193040
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http://dx.doi.org/10.1016/j.gene.2019.04.051DOI Listing
April 2019
1 Read

Stabilizing Terminal Ni(III)-Hydroxide Complex Using NNN-Pincer Ligands: Synthesis and Characterization.

Inorg Chem 2019 Apr 22. Epub 2019 Apr 22.

Department of Chemistry , Indian Institute of Technology Bombay , Powai - 400076 , Mumbai , Maharashtra , India.

The reaction of [Ni(COD)] (COD; cyclooctadiene) in THF with the NNN-pincer ligand bis(imino)pyridyl (L) reveals a susceptibility to oxidation in an inert atmosphere ([O] level <0.5 ppm), resulting in a transient Ni:dioxygen adduct. This reactive intermediate abstracts a hydrogen atom from THF and stabilizes an uncommon Ni(III) complex. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.9b00466DOI Listing

Sustainable Synthesis of Quinazoline and 2-Aminoquinoline via Dehydrogenative Coupling of 2-Aminobenzyl Alcohol and Nitrile Catalyzed by Phosphine-Free Manganese Pincer Complex.

Org Lett 2019 Apr 22. Epub 2019 Apr 22.

Department of Chemistry , Indian Institute of Technology-Guwahati , Kamrup , Assam 781039 , India.

A sustainable synthesis of quinazoline and 2-aminoquinoline via acceptorless dehydrogenative annulation is presented. The reaction is catalyzed by earth-abundant well-defined manganese complexes bearing NNS ligands. Furthermore, a one-pot synthetic strategy for the synthesis of 2-alkylaminoquinolines through sequential dehydrogenative annulation and N-alkylation reaction has also been demonstrated. Read More

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http://dx.doi.org/10.1021/acs.orglett.9b00939DOI Listing

Polycomb complex mediated epigenetic reprogramming alters TGF-β signaling via a novel EZH2/miR-490/TGIF2 axis thereby inducing migration and EMT potential in glioblastomas.

Int J Cancer 2019 Apr 22. Epub 2019 Apr 22.

Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, New Delhi- 110016, IN.

Recent advancement in understanding cancer etiology has highlighted epigenetic deregulation as an important phenomenon leading to poor prognosis in Glioblastoma (GBM). Polycomb Repressive Complex 2 (PRC2) is one such important epigenetic modifier reportedly altered in GBM. However, its defined mechanism in tumorigenesis still remains elusive. Read More

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http://dx.doi.org/10.1002/ijc.32360DOI Listing

The epidemic of Dengue virus type-2 Cosmopolitan genotype on Reunion Island relates to its active circulation in the Southwestern Indian Ocean neighboring islands.

Heliyon 2019 Apr 10;5(4):e01455. Epub 2019 Apr 10.

Université de La Réunion, UMR PIMIT "Processus Infectieux en Milieu Insulaire Tropical", INSERM U1187, CNRS 9192, IRD 249, Plateforme de Recherche CYROI, Saint Clotilde, La Réunion, France.

Reunion Island is currently experiencing an epidemic caused by Dengue virus type-2 (DENV-2) resulting in over 6,763 cases from austral summer 2017 to winter 2018. Phylogenetic analyses on two non-imported cases of dengue infection from Reunion Island highlight a regional circulation of DENV-2 Cosmopolitan lineage 1 virus on both Reunion Island and the Seychelles. Read More

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http://dx.doi.org/10.1016/j.heliyon.2019.e01455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458493PMC

The assessment of the quality of randomized controlled trials published in Indian medical journals.

Perspect Clin Res 2019 Apr-Jun;10(2):79-83

Department of Clinical Pharmacology, SRM MCH and RC, Kattankulathur, Kancheepuram, Chennai, Tamil Nadu, India.

Aim: In this retrospective cross-sectional study, we sought to evaluate if the published randomized controlled trials (RCTs) reported in the year 2017 among the Indian medical journals (IMJs) complied with the Consolidated Standards of Reporting Trials (CONSORT) guidelines and identify domains where reporting could be improved.

Methods: A literature search was performed using PubMed and Google Scholar to identify all the IMJs that published RCTs in the year 2017. In the archives of the identified journals, the number of published RCTs was identified and the full text was obtained. Read More

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http://dx.doi.org/10.4103/picr.PICR_60_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463507PMC

Conducting real-world evidence studies in India.

Authors:
Arun Bhatt

Perspect Clin Res 2019 Apr-Jun;10(2):51-56

Consultant - Clinical Research and Development, Mumbai, Maharashtra, India.

Real-world data (RWD) are data relating to patients' health status and/or the delivery of health care routinely collected from a variety of sources. Real-world evidence (RWE) is the clinical evidence regarding the usage and potential benefits or risks of a medical product derived from analysis of RWD. RWE can provide information on diverse areas, for example, natural history and course of disease, effectiveness studies, outcome research, and safety surveillance. Read More

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http://dx.doi.org/10.4103/picr.PICR_8_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463503PMC

WISHE-Moisture Mode in an Aquaplanet Simulation.

J Adv Model Earth Syst 2018 Oct 12;10(10):2393-2407. Epub 2018 Oct 12.

Centre for Atmospheric and Oceanic Sciences Indian Institute of Science Bangalore India.

This study aims to understand the nature of the tropical intraseasonal oscillations (ISOs) in an aquaplanet simulation performed using Geophysical Fluid Dynamics Laboratory's AM2.1 with a uniform sea surface temperature within the deep tropics. The simulated ISO resembles the observed Madden-Julian Oscillation in that the spectral peak in precipitation appears at zonal wave number 1 and a period of ~60 days. Read More

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http://dx.doi.org/10.1029/2018MS001441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472665PMC
October 2018

Bed particle saltation in turbulent wall-shear flow: a review.

Proc Math Phys Eng Sci 2019 Mar 13;475(2223):20180824. Epub 2019 Mar 13.

Department of Civil Engineering, Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal, India.

Bed particle saltation in turbulent wall-shear flow remains an intriguing phenomenon in applied hydro-dynamics. In this review, we report the current state of the art of bed particle saltation in turbulent wall-shear flow, highlighting the physical characteristics of bed particle saltation and its mathematical modelling. A critical appraisal of the mechanics of bed particle saltation is presented thorough ample experimental evidence. Read More

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http://dx.doi.org/10.1098/rspa.2018.0824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451974PMC

Partitioning a reaction-diffusion ecological network for dynamic stability.

Proc Math Phys Eng Sci 2019 Mar 13;475(2223):20180524. Epub 2019 Mar 13.

Department of Computational and Data Sciences, Indian Institute of Science, Bangalore 560012, India.

The loss of dispersal connections between habitat patches may destabilize populations in a patched ecological network. This work studies the stability of populations when one or more communication links is removed. An example is finding the alignment of a highway through a patched forest containing a network of metapopulations in the patches. Read More

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http://dx.doi.org/10.1098/rspa.2018.0524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451970PMC

Comparison of Vacuum-Assisted Closure Therapy and Conventional Dressing on Wound Healing in Patients with Diabetic Foot Ulcer: A Randomized Controlled Trial.

Niger J Surg 2019 Jan-Jun;25(1):14-20

Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Background: Vacuum-assisted closure (VAC) therapy has been shown to be beneficial in a variety of wounds. However, evidence of its benefit in diabetic foot ulcers (DFUs), especially with respect to Indian population, is sparse.

Methodology: This randomized controlled trial included DFUs of Wagner's Grades 1 and 2. Read More

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http://www.nigerianjsurg.com/text.asp?2019/25/1/14/253776
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http://dx.doi.org/10.4103/njs.NJS_14_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452767PMC
April 2019
1 Read

Repeating Acute-Onset Hemiballismus in Association with Distinct Stroke Regions in a Single Patient.

Authors:
Halil Onder

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):255-257

Department of Neurology, Yozgat City Hospital, Yozgat, Turkey.

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http://dx.doi.org/10.4103/aian.AIAN_282_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472248PMC

Neuropsychiatric Lupus: The Devil is in the Detail.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):253-255

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.4103/aian.AIAN_236_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472238PMC

Mimickers of Amyotrophic Lateral Sclerosis.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):252-253

Department of Neurology, Meenakshi Medical College Hospital and Research Institute, Kanchipuram, Tamil Nadu, India.

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http://dx.doi.org/10.4103/aian.AIAN_452_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472250PMC

Recurrent Stroke Due to Antiphospholipid Syndrome Remitted by Immunotherapy, Not by Anticoagulation Therapy: A Case Report and Literature Review.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):250-252

Department of Neurology, Dongguk University College of Medicine, Dongdae-Ro, Gyeongju 38067, Korea.

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http://dx.doi.org/10.4103/aian.AIAN_433_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472235PMC

Comments on "Short-lasting, unilateral, neuralgiform headache attacks".

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):249-250

Department of Neurosurgery, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.

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http://dx.doi.org/10.4103/aian.AIAN_353_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472229PMC

Reversible Spastic Paraparesis.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):246-247

Department of Pediatrics, Division of Pediatric Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.4103/aian.AIAN_351_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472219PMC

Heat Hyperpyrexia-Induced Cerebellar Degeneration and Anterior Horn Cell Degeneration: A Rare Manifestation.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):244-245

Department of Radio Diagnosis and Modern Imaging, Government Medical College, Kota, Rajasthan, India.

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http://dx.doi.org/10.4103/aian.AIAN_333_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472222PMC

Rivaroxaban: A Possible Cause of Guillain-Barre Syndrome.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):242-244

Department of Neurology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.

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http://dx.doi.org/10.4103/aian.AIAN_331_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472232PMC

Pharyngeal-Cervical-Brachial Variant of Guillain-Barré Syndrome Following Dengue Infection: A Rare Syndrome with Rare Association.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):240-241

Department of Medicine, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India.

Pharyngeal-cervical-brachial (PCB) variant is a rare localized variant of Guillain-Barré syndrome that presents with a rapidly progressive oropharyngeal and cervicopharyngeal weakness associated with areflexia in the upper limb. Here, we are describing a case of a 20-year-old female who had a preceding history of fever with thrombocytopenia that was found to be dengue ELISA positive. This was followed by rapidly progressive weakness of cervical, bulbar, and bilateral facial muscles along with areflexia of upper limb. Read More

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http://dx.doi.org/10.4103/aian.AIAN_253_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472218PMC

Long-Segment Myelitis, Meningoencephalitis, and Axonal Polyneuropathy in a Case of Scrub Typhus.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):237-240

Department of Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.

Scrub typhus, a mite-borne zoonotic disease, is endemic in several parts of India. It may cause multisystemic disease involving lungs, heart, spleen, liver, hematological system, and nervous system. Neurological involvement may include meningoencephalitis, cerebellitis, cranial nerve palsies, plexopathy, transverse myelitis, muscle dysfunction, neuroleptic malignant syndrome, parkinsonian syndrome, and Guillain-Barre syndrome. Read More

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http://www.annalsofian.org/preprintarticle.asp?id=243807
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http://dx.doi.org/10.4103/aian.AIAN_66_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472236PMC
April 2019
1 Read

Disseminated Strongyloidiasis: Breaking Brain Barriers.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):234-237

Department of Infectious Diseases, Wayne State School of Medicine, Detroit, Michigan, USA.

(SS) is one of the most overlooked helminthic infections despite being highly endemic in tropical and subtropical areas. In immunocompromised patients, especially those on long-term steroids, infection can often escalate to fatal dissemination into major organs. We present a compendium of two immunocompromised patients, who were on high-dose steroids and presented with worsening neurological status. Read More

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http://www.annalsofian.org/preprintarticle.asp?id=249718
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http://dx.doi.org/10.4103/aian.AIAN_321_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472231PMC
April 2019
1 Read

Immunodeficiency, Motor Delay, and Hypouricemia Caused by a Novel Mutation of Purine Nucleoside Phosphorylase Gene in an Indian Infant.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):231-233

Department of Clinical Genetics, MedGenome Laboratory, Bengaluru, Karnataka, India.

We describe an 11-month-old boy who presented with recurrent respiratory infections from 6 months of age. His elder sister died at 10 months with severe septicemia and meningitis. The boy had a mild motor delay. Read More

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http://dx.doi.org/10.4103/aian.AIAN_430_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472228PMC

Muscle Biopsy: A Boon for Diagnosis of Mitochondrial Parkinsonism in Developing Countries.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):228-230

Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Mitochondrial dysfunction plays an important role in the pathogenesis of Parkinson's disease. Primary genetic abnormalities in the mitochondrial DNA or nuclear DNA can cause parkinsonism. Mitochondrial parkinsonism presents with classical features of parkinsonism along with multisystem involvement. Read More

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http://dx.doi.org/10.4103/aian.AIAN_436_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472221PMC

Familial Creutzfeldt-Jakob Disease: The First Reported Kindred from South-East Asia.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):225-227

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Creutzfeldt-Jakob disease (CJD) belongs to a group of prion disease that is caused by abnormally folded proteins and is clinically characterized by rapidly progressive cognitive decline, gait abnormalities, and myoclonus. Familial CJD is very rare and is described only in few families around the world. We report a case with rapidly progressive cognitive decline, ataxia, and myoclonus, with a history of several members of his family developing similar symptoms and succumbing to it. Read More

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http://dx.doi.org/10.4103/aian.AIAN_441_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472217PMC

Unilateral Thalamic Infarct: A Rare Presentation of Deep Cerebral Venous Thrombosis.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):221-224

Department of Imaging and Interventional Radiology, Kerala Institute of Medical Sciences, Thiruvananthapuram, Kerala, India.

Deep cerebral venous thrombosis (DCVT) remains a very rare entity among the spectrum of cerebral venous thrombosis (CVT). Due to the bilateral draining territories, DCVT nearly invariably causes bilateral infarction with predictably dismal prognosis. However, rare instances of DCVT with unilateral infarction having favorable prognosis have been described, but pose a wide range of differentials to the clinician and require careful interpretation of clinical and radiological features for accurate diagnosis. Read More

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http://dx.doi.org/10.4103/aian.AIAN_488_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472245PMC

A Case of Rare Inflammatory Brainstem Syndrome: Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):219-220

Department of Neurology, The Ganga Ram Institute of Post-graduate Medical Education and Research, Sir Ganga Ram Hospital, New Delhi, India.

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http://dx.doi.org/10.4103/aian.AIAN_370_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472233PMC

Dancing Scapula: The Missed Movement.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):218-219

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.4103/aian.AIAN_210_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472239PMC

Boomerang in the Brain.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):217-218

Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.4103/aian.AIAN_447_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472220PMC

Erratum: Florid Nonmotor Manifestations of a Pathologically proven Progressive Supranuclear Palsy.

Authors:

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):216

[This corrects the article on p. 345 in vol. 21, PMID: 30532377. Read More

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http://dx.doi.org/10.4103/0972-2327.255691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472240PMC

Assessment of Neurodegeneration by Optical Coherence Tomography and Mini-Mental Test in Parkinson's Disease.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):212-216

Department of Biostatistics, Uludag University Faculty of Medicine, Bursa, Turkey.

Background: Parkinson's disease is a neurodegenerative disease. Cognitive disorders and retinal degeneration may occur during the early stages of the disease. Retinal degeneration and cognitive findings can be assessed easily with optical coherence tomography and mini-mental test, respectively. Read More

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http://dx.doi.org/10.4103/aian.AIAN_424_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472223PMC

Rare Complication of Carotid Stenting: New-Onset Refractory Status Epilepticus: A Study of Five Patients.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):210-212

Department of Neurology, Bombay Hospital and Institute of Medical Sciences, Mumbai, Maharashtra, India.

Introduction: New-onset refractory status epilepticus (NORSE) is uncommon and almost 50% of cases are cryptogenic. We report the rare development of NORSE following carotid artery stenting (CAS), a procedure which is increasingly being used to treat the carotid stenosis.

Materials And Methods: Patients who developed NORSE following CAS for the prevention of stroke over a period of 5 years were analyzed retrospectively. Read More

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http://dx.doi.org/10.4103/aian.AIAN_445_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472247PMC

Fractional Amplitude of Low-Frequency Fluctuations and Functional Connectivity in Comatose Patients Subjected to Resting-State Functional Magnetic Resonance Imaging.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):203-209

Department of Radiology, Changsha Central Hospital, Changsha, China.

Objective: The objective of the study is to investigate the changes of fractional amplitude of low-frequency fluctuations (fALFFs) and functional connectivity (FC) in the brain function of comatose patients with resting-state blood-oxygenation-level-dependent functional magnetic resonance imaging (BOLD-fMRI) and to discuss the underlying neurophysiological mechanism of disease.

Materials And Methods: Resting-state BOLD-fMRI scans were conducted on 20 comatose patients and 20 age-matched and gender-matched controls. The differences of fALFF between two groups were analyzed with two-sample -test; significant differences of connectivity between groups were acquired to calculate the FC of the precuneus with other brain regions. Read More

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http://dx.doi.org/10.4103/aian.AIAN_420_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472252PMC

Multipronged Treatment of Insomnia - Outcomes from an Apex Sleep Disorders Clinic in India.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):199-202

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Introduction: A large proportion of the population suffers from disturbed sleep and a majority of these present to clinicians with the complaint of insomnia. Many of these people possibly suffer from other primary sleep disorders such as sleep apnea; however, insomnia disorder also remains an extremely common condition directly impacting the quality of life and work efficiency of affected people. While a number of approaches are used for treatment by many clinicians, a much smaller percentage can seek help from specialty sleep clinics. Read More

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http://dx.doi.org/10.4103/aian.AIAN_57_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472226PMC

Transcranial Doppler and Hematoma Expansion in Acute Spontaneous Primary Intracerebral Hemorrhage.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):195-198

Department of Radiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Context: The data on the role of Transcranial Doppler (TCD) in the management of acute primary intracerebral hemorrhage (ICH) is meager.

Aims: To study TCD variables associated with hematoma expansion in acute primary ICH.

Settings And Design: The study was carried out in the neurosciences department of Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh from July 2010 to September 2011 employing a prospective, double blinded non randomized study design. Read More

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http://www.annalsofian.org/preprintarticle.asp?id=144277
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http://dx.doi.org/10.4103/0972-2327.144277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472244PMC
April 2019
1 Read

Study of Middle Cerebral Artery in Human Cadaveric Brain.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):187-194

Department of Anatomy, Rural Medical College, PIMS, Loni, Maharashtra, India.

Background: Middle cerebral artery (MCA) is the larger terminal branch of the internal carotid artery. It travels through the Sylvian fissure on the insula.

Objective: MCA supplies a large area of distribution than the other two cerebral arteries. Read More

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http://www.annalsofian.org/preprintarticle.asp?id=144289
Publisher Site
http://dx.doi.org/10.4103/0972-2327.144289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472224PMC
April 2019
1 Read

Vasculitic Neuropathy: A Retrospective Analysis of Nerve Biopsies and Clinical Features from a Single Tertiary Care Center.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):180-186

Department of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.

Objective: Vasculitic neuropathy can be either restricted to the peripheral nerves or associated with systemic involvement of other organs. The objective of this study was to analyze the nerve biopsies reported as "vasculitic neuropathy" with clinical features.

Materials And Methods: All cases diagnosed with vasculitic neuropathy were retrospectively analyzed and categorized as systemic vasculitis and nonsystemic vasculitic neuropathy based on the clinical features. Read More

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http://dx.doi.org/10.4103/aian.AIAN_47_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472243PMC

Terminal Latency Index, Residual Latency, and Median-Ulnar F-Wave Latency Difference in Carpal Tunnel Syndrome.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):175-179

Department of Physical Medicine and Rehabilitation, Private Derman Hospital, Kirklareli, Turkey.

Introduction: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy, but no electrodiagnostic test alone shows sufficient sensitivity for CTS. We aimed to investigate the value of median motor terminal latency index (mTLI), median motor residual latency (mRL), and median-ulnar F-wave latency difference (FdifMU) as additional tests to nerve conduction studies which are performed traditionally in electromyography laboratories.

Methods: This is a retrospective study. Read More

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http://dx.doi.org/10.4103/aian.AIAN_276_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472246PMC

Storage, Degradation, and New Connectivity of Face-Related Semantic Memory in Alzheimer's Disease.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):170-174

Department of Neurology, Medical College Hospital, Kolkata, West Bengal, India.

Background: Excepting amnesia, impairment of other domains also hampers the activity of daily living in Alzheimer's disease (AD). Although prosopagnosia poses problem in interacting with other persons, it rarely causes problem during interaction with close relatives as known voice acts as cue for recognition.

Objective: In a cohort of AD, we planned to study errors in recognition, naming, and assigning relationship of close relatives, to assess the type and frequency of errors and to explain with current knowledge and hypothesis. Read More

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http://dx.doi.org/10.4103/aian.AIAN_185_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472242PMC

A Study of Assessment of Knowledge of Childhood Autism among Medical Students in Mumbai.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):164-169

Department of Psychiatry, Topiwala National Medical College and BYL Charitable Nair Hospital, Mumbai, Maharashtra, India.

Aims: This study is to study the knowledge and awareness on autism among medical students and the factors which impact their knowledge on autism.

Settings And Design: For the study, a multicenter cross-sectional research has been carried out among medical students in seven medical colleges in Mumbai.

Subjects And Methods: A total of 201 final-year medical students from seven medical colleges in Mumbai completed the knowledge on childhood autism among healthcare workers (KCAHW) survey and a semi-structured pro forma. Read More

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http://dx.doi.org/10.4103/aian.AIAN_486_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472225PMC

Study of Wrist Ratio and Wrist-to-Palm Index Radio in Individuals Suffering from Carpal Tunnel Syndrome.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):159-163

Department of Community Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji vidyapeeth (Deemed to be University) Puducherry, India.

Background: Carpal tunnel syndrome (CTS) is the commonest median nerve entrapment neuropathy, with preponderance in females.

Aims And Objective: The aim of the present study was to find out wrist ratio (WR) and wrist/palm ratio (WPR) in clinically diagnosed patients of CTS.

Methodology: One hundred individuals (fifty patients of CTS and fifty as control group) aged between 30 and 50 years were recruited for the study. Read More

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http://dx.doi.org/10.4103/aian.AIAN_343_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472216PMC

Scrub Typhus-Associated Opsoclonus: Clinical Course and Longitudinal Outcomes in an Indian Cohort.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):153-158

Department of Infectious Diseases, Christian Medical College Hospital, Vellore, Tamil Nadu, India.

Context: Opsoclonus, a rare neurological manifestation in scrub typhus, causes significant distress and disability. There is a paucity of clinical data and outcomes in these patients.

Aim: This study aims to describe the clinical and laboratory profile and longitudinal outcomes in a scrub typhus patient cohort with opsoclonus. Read More

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http://dx.doi.org/10.4103/aian.AIAN_198_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472253PMC

Aspirin and Clopidogrel Resistance in Indian Patients with Ischemic Stroke and its Associations with Gene Polymorphisms: A Pilot Study.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):147-152

Department of Neurology, Sir Ganga Ram Hospital, New Delhi, India.

Introduction: Antiplatelet resistance is one of the urgent issues in current stroke care. One-third to one-half of the patients who experience a recurrent stroke is already on antiplatelet medications. We studied resistance to aspirin and clopidogrel in Indian stroke patients and its association with gene polymorphisms. Read More

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http://dx.doi.org/10.4103/aian.AIAN_4_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472234PMC

Expert Group Meeting on Aphasia: A Report.

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):137-146

Aphasia Research Center, Maryland, USA.

A multidisciplinary team of experts took stock of the current state of affairs about many aspects of aphasia in India, including community burden, diagnostic assessment, therapy, rehabilitation, research, education, and advocacy. The broad spectrum of aphasiology was matched by the types of participants ranging from neurologists, speech-language pathologists, clinical psychologists, linguists, to experts in neuroimaging and computer sciences. Threadbare discussion in 16 sessions over 3 days leads to the identification of pressing problems and possible solutions. Read More

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http://dx.doi.org/10.4103/aian.AIAN_330_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472241PMC

Can We Treat Secondary Progressive Multiple Sclerosis Now?

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):131-136

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Secondary progressive multiple sclerosis (SPMS) is characterized by progressive accumulation of disability without intermittent recovery. Treatment of these patients is challenging due to limited understanding of pathogenesis and fewer therapeutic options. This article summarizes difficulties in defining and conducting trials in SPMS, review major clinical trials on therapies approved and unapproved in SPMS and lastly, therapies in pipeline for use in SPMS. Read More

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http://dx.doi.org/10.4103/aian.AIAN_345_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472227PMC

Cross-cultural Differences in Dementia: Indian Etiquette of Honorifics.

Authors:
Apoorva Pauranik

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):129-130

Director, Pauranik Academy of Medical Education, Ex-Professor, Medicine and Neurology, M.G.M. Medical College, Indore, Madhya Pradesh, India.

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http://dx.doi.org/10.4103/aian.AIAN_404_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472237PMC

Social networks, mobility, and political participation: The potential for women's self-help groups to improve access and use of public entitlement schemes in India.

World Dev 2019 Feb;114:28-41

International Food Policy Research Institute, Washington, DC, United States.

Women's self-help groups (SHGs) have increasingly been used as a vehicle for social, political, and economic empowerment as well as a platform for service delivery. Although a growing body of literature shows evidence of positive impacts of SHGs on various measures of empowerment, our understanding of ways in which SHGs improve awareness and use of public services is limited. To fill this knowledge gap, this paper first examines how SHG membership is associated with political participation, awareness, and use of government entitlement schemes. Read More

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http://dx.doi.org/10.1016/j.worlddev.2018.09.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472676PMC
February 2019