259,918 results match your criteria Indian journal of dermatology venereology and leprology[Journal]


Efficacy of vermitechnology integration with Upflow Anaerobic Sludge Blanket (UASB) and activated sludge for metal stabilization: A compliance study on fractionation and biosorption.

J Environ Manage 2019 Feb 13;236:603-612. Epub 2019 Feb 13.

Discipline of Earth Science, Indian Institute of Technology Gandhinagar, 382355, Gujarat, India. Electronic address:

Efficacy of vermi-transformation for metal partitioning and transformation from Upflow Anaerobic Sludge Blanket (UASB) and Activated Sludge (AS) was investigated. Sludge samples were mixed with cow dung (CD) in two combinations (1:1 (UASB/AS:CD)) & (2:1(UASB/AS: CD)). Fractionation study revealed that Zn, Cd & Pb were associated with reducible fractions, and Cr, Cu with oxidizable fractions. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.01.006DOI Listing
February 2019

Engineered microbial host selection for value-added bioproducts from lignocellulose.

Biotechnol Adv 2019 Feb 13. Epub 2019 Feb 13.

Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. Electronic address:

Lignocellulose is a rich and sustainable globally available carbon source and is considered a prominent alternative raw material for producing biofuels and valuable chemical compounds. Enzymatic hydrolysis is one of the crucial steps of lignocellulose degradation. Cellulolytic and hemicellulolytic enzyme mixes produced by different microorganisms including filamentous fungi, yeasts and bacteria, are used to degrade the biomass to liberate monosaccharides and other compounds for fermentation or conversion to value-added products. Read More

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http://dx.doi.org/10.1016/j.biotechadv.2019.02.003DOI Listing
February 2019

Improvement of structural stability and functional efficiency of chaperonin GroEL mediated by mixed salt.

Int J Biol Macromol 2019 Feb 13. Epub 2019 Feb 13.

Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, India. Electronic address:

GroEL is the most commonly used chaperonin protein for both in-vitro refolding of aggregating proteins as well as in-vivo solubilization of over-expressed aggregation-prone proteins of therapeutic and biotechnological applications. But sometimes the stress conditions like heat and a load of over-expressed/unfolded/misfolded proteins lead to a decrease in structural stability and functional efficiency of GroEL, which results in less recovery of substrate protein through the chaperone-mediated refolding process. So, to amend it, we have been able to optimize physicochemical conditions utilizing a cumulation of (NH)SO/MgCl in the buffer. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.02.069DOI Listing
February 2019

Heterogeneous network dynamics in an Excitatory-Inhibitory network model by distinct intrinsic mechanisms in the Fast spiking interneurons.

Brain Res 2019 Feb 13. Epub 2019 Feb 13.

Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India. Electronic address:

Fast spiking interneurons (FSINs) have an important role in neuronal network dynamics. Although plasticity of synaptic properties is known to affect network synchrony, the role of plasticity of FSINs' intrinsic excitability on network dynamics remain elusive. Using computational approaches in an excitatory-FSIN model network (EI) based on previously established hippocampal neuronal models we show that altered FSIN intrinsic excitability robustly affects the coherence and frequency of network firing monotonically in the connected excitatory network. Read More

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http://dx.doi.org/10.1016/j.brainres.2019.02.013DOI Listing
February 2019

Association and gene-gene interaction analyses for polymorphic variants in CTLA-4 and FOXP3 genes: role in susceptibility to autoimmune thyroid disease.

Endocrine 2019 Feb 15. Epub 2019 Feb 15.

Department of Genetics, Osmania University, Hyderabad, Telangana, India.

Purpose: Polymorphic variants of cytotoxic T-lymphocyte antigen-4 (CTLA-4) and forkhead box protein P3 (FOXP3) genes are implicated in dysregulated immune homeostasis and autoimmune disorders. We analyzed the association between CTLA-4 rs231775 and FOXP3 rs3761548, rs3761549 polymorphisms and predisposition to autoimmune thyroid disease (AITD), inclusive of Hashimoto's thyroiditis (HT) and Graves' disease (GD) in South-Indian population.

Methods: A total of 355 AITD subjects (comprising 275 HT and 80 GD) and 285 randomly selected age- and sex-matched control subjects were genotyped for the aforementioned polymorphisms by PCR-RFLP method. Read More

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http://dx.doi.org/10.1007/s12020-019-01859-3DOI Listing
February 2019

A novel nano zero-valent iron biomaterial for chromium (Cr to Cr) reduction.

Environ Sci Pollut Res Int 2019 Feb 15. Epub 2019 Feb 15.

Department of Chemical Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247 667, India.

This research work aims to develop a biomaterial entrapped with iron nanoparticles by green synthesis method in which biomass act as both reducing and capping agent. Iron nanoparticles embedded in Citrus limetta peels were characterised using ICP-MS for determination of metal loading, XRD, XPS for crystallinity and oxidation states, TEM followed by FESEM-EDS for particle size and morphology. Sizes of nanoparticles were found to be in the range of 4-70 nm. Read More

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http://dx.doi.org/10.1007/s11356-019-04528-0DOI Listing
February 2019

Mature landfill leachate treatment using sonolytic-persulfate/hydrogen peroxide oxidation: Optimization of process parameters.

Ultrason Sonochem 2019 Jan 29. Epub 2019 Jan 29.

Environmental and Water Resources Engineering Division, Department of Civil Engineering, Indian Institute of Technology Madras, Tamilnadu, India. Electronic address:

The suitability of stand-alone ultrasound (US) system, coagulation pre-treatment followed by US, hydrogen peroxide added US system (US-HO) and persulfate added US system (US-PS) for the treatment of matured landfill leachate was investigated. With US system, around 67% COD removal and an increase in BOD/COD ratio were observed (from 0.033 to 0. Read More

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http://dx.doi.org/10.1016/j.ultsonch.2019.01.036DOI Listing
January 2019

Efficient HF exchange evaluation through Fourier convolution in Cartesian grid for orbital-dependent density functionals.

J Chem Phys 2019 Feb;150(6):064104

Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Nadia, Mohanpur, WB 741246, India.

We present a purely numerical approach in a Cartesian grid, for efficient computation of the Hartree-Fock (HF) exchange contribution in the HF and density functional theory models. This takes inspiration from a recently developed algorithm by Liu et al., in 2017, where the rate-determining step is the accurate evaluation of electrostatic potential. Read More

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http://dx.doi.org/10.1063/1.5082393DOI Listing
February 2019

Total ionization cross section of cyclic organic molecules.

J Chem Phys 2019 Feb;150(6):064313

Plasma Technology Research Center, National Fusion Research Institute, 37 Dongjangsan-ro, Gunsan, Jeollabuk-do 54004, South Korea.

Two independent methods, namely, Binary-encounter Bethe (BEB) and complex scattering potential-ionization contribution (CSP-ic) methods, are employed to calculate the total ionization cross section (Q) for cyclic organic molecules from ionization threshold to 5 keV for which there is a paucity of data in the literature. The Q calculated with the (BEB/ωB97X) combination is found to give good agreement with the experimental results, the CSP-ic method, and the Q calculated from Irikura orbital energies. The Q for most of the targets are calculated for the first time over such a wide energy range. Read More

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http://dx.doi.org/10.1063/1.5081841DOI Listing
February 2019

Aggregation and sedimentation of active Brownian particles at constant affinity.

J Chem Phys 2019 Feb;150(6):064910

Institut für Physik, Johannes Gutenberg-Universität Mainz, Staudingerweg 7-9, 55128 Mainz, Germany.

We study the motility-induced phase separation of active particles driven through the interconversion of two chemical species controlled by ideal reservoirs (chemostats). As a consequence, the propulsion speed is non-constant and depends on the actual inter-particle forces, enhancing the positive feedback between increased density and reduced motility that is responsible for the observed inhomogeneous density. For hard discs, we find that this effect is negligible and that the phase separation is controlled by the average propulsion speed. Read More

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http://dx.doi.org/10.1063/1.5081115DOI Listing
February 2019

Cubic perturbed centrifugally stabilized excited state in orthorhombic manganites.

J Chem Phys 2019 Feb;150(6):064703

Lebedev Physical Institute, Russian Academy of Sciences, Moscow 119991, Russia.

A model Hamiltonian for centrifugally stabilized electronic-vibrational motion of a cubic perturbed upper "Mexican hat" potential surface for a Mn ion in an octahedral symmetry is formulated, and its eigenspectrum is explored. Theoretically calculated eigenvalues for cubic perturbed ground and excited electronic states are employed to interpret the origin of higher energy narrow side bands (satellite transitions) appearing in the dielectric function spectra of the LaMnO complex, which exhibit anomalous temperature dependence in the vicinity of the Néel temperature, T ≃ 140 K [N. N. Read More

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http://dx.doi.org/10.1063/1.5082008DOI Listing
February 2019

How does temperature modulate the structural properties of aggregated melamine in aqueous solution-An answer from classical molecular dynamics simulation.

J Chem Phys 2019 Feb;150(6):064501

Department of Chemistry, Indian Institute of Technology, Guwahati 781039, Assam, India.

In this study, classical molecular dynamics simulation of eight melamine molecules is carried out in water over a temperature range of 300 K to 380 K at an ambient pressure to examine the molecular details of melamine aggregation along with the impact of temperature on the aggregated state of melamine in water. It is found that the hydrogen bonds formed between sp N-sp N of melamine, which is mainly responsible for the aggregation over the sp N-sp N, are disturbed mainly by the rise in temperature. These outcomes are complemented by the consideration of an average number of hydrogen bonds per melamine and preferential interaction parameter calculations. Read More

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http://dx.doi.org/10.1063/1.5066388DOI Listing
February 2019

Conical intersections and nonadiabatic coupling terms in 1,3,5-CHF: A six state beyond Born-Oppenheimer treatment.

J Chem Phys 2019 Feb;150(6):064308

School of Chemical Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India.

In order to circumvent numerical inaccuracy originating from the singularity of nonadiabatic coupling terms (NACTs), we need to perform kinetically coupled adiabatic to potentially coupled diabatic transformation of the nuclear Schrödinger Equation. Such a transformation is difficult to achieve for higher dimensional sub-Hilbert spaces due to inherent complicacy of adiabatic to diabatic transformation (ADT) equations. Nevertheless, detailed expressions of ADT equations are formulated for six coupled electronic states for the first time and their validity is extensively examined for a well-known radical cation, namely, 1,3,5-CHF (TFBZ). Read More

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http://dx.doi.org/10.1063/1.5064519DOI Listing
February 2019

Colonic Diaphragm Disease: An Important NSAID Complication to Know.

Fed Pract 2017 Mar;34(3):38-40

is a hospitalist, and is chief, internal medicine, both at the Phoenix Indian Medical Center in Arizona.

Given the widespread use of nonsteroidal anti-inflammatory drugs, physicians should recognize the symptoms of colonic diaphragm disease, a rare but serious complication that can affect the large and small intestines. Read More

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Responding to the Opioid Crisis: An Indian Health Service Pharmacist-Led Pain Management Clinic.

Authors:
Neha N Patel

Fed Pract 2017 Nov;34(11):40-45

is a clinical staff pharmacist at Gallup Indian Medical Center in New Mexico.

An IHS pharmacy pain management clinic has emphasized judicious opioid prescribing, reduced overdose risk in the community, and improved patient functionality and quality of care through close pharmacotherapy monitoring. Read More

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November 2017

Patient-Centered HIV Treatment Options: Practical Considerations.

Fed Pract 2015 Feb;32(Suppl 2):4S-9S

is the acting director of the HIV Center of Excellence, is an HIV certified pharmacist, and is an HIV certified physician practicing at the Phoenix Indian Medical Center in Phoenix, Arizona.

Physicians should be aware of the advantages and disadvantages of each antiretroviral class and be aware of patients' lifestyles when choosing an individualized regimen. Read More

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February 2015

A Multidisciplinary Chronic Pain Management Clinic in an Indian Health Service Facility.

Fed Pract 2015 Aug;32(8):24-30

, , , and are all pharmacists with the Indian Health Service. is a pharmacist at Charles George VAMC in Asheville, North Carolina.

The creation of a pharmacist-managed pain clinic has led to improved patient outcomes, pain medication adherence, and patient satisfaction while relieving primary care and emergency department providers. Read More

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Emergence of Virulence to Sr25 of Puccinia graminis f. sp. tritici on Wheat in India.

Plant Dis 2009 Aug;93(8):840

Regional Station, Directorate of Wheat Research (ICAR), Flowerdale, Shimla-171 002, Himachal Pradesh, India.

Stem (black) rust, caused by Puccinia graminis Pers. f. sp. Read More

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http://dx.doi.org/10.1094/PDIS-93-8-0840BDOI Listing

First Report of Garlic common latent virus in Garlic from India.

Plant Dis 2009 Jan;93(1):106

Plant Virology Unit, Division of Plant Pathology, Indian Agricultural Research Institute, New Delhi, 110012, India.

Garlic (Allium sativum L.) is one of the most important culinary herbs in the Indian subcontinent. Several viruses belonging to genera Potyvirus, Carlavirus, and Allexivirus are known to infect garlic (2,3). Read More

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http://dx.doi.org/10.1094/PDIS-93-1-0106CDOI Listing
January 2009

Detection of Wheat Stem Rust (Puccinia graminis f. sp. tritici) Race TTKSK (Ug99) in Iran.

Plant Dis 2009 Mar;93(3):317

University of Sydney, Plant Breeding Institute, PMB 11, Camden NSW 2570, Australia.

In 2007, new reports of stem rust caused by Puccinia graminis Pers. f. sp. Read More

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http://dx.doi.org/10.1094/PDIS-93-3-0317BDOI Listing

First Report of Leaf Blight on Foxglove (Digitalis purpurea) Caused by Rhizoctonia solani AG-1-IA in Italy.

Plant Dis 2009 Mar;93(3):318

Center of Competence AGROINNOVA, University of Torino, Via Leonardo da Vinci, 44, 10095 Grugliasco, Italy.

Digitalis purpurea (Scrophulariaceae), foxglove, is used in flower gardens. In the spring of 2008, leaf blight was observed in a nursery near Biella (northern Italy) on 30% of potted 30-day-old plants grown in a peat substrate at temperatures from 20 to 25°C and relative humidity at 75 to 80%. Semicircular, water-soaked lesions developed on leaves just above the soil line at the blade-petiole junction and later along the leaf margins. Read More

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http://dx.doi.org/10.1094/PDIS-93-3-0318CDOI Listing

First Report of Bacterial Wilt of Tomato (Solanum lycopersicum) Caused by Ralstonia solanacearum in Benin.

Plant Dis 2009 May;93(5):549

Institute of Plant Diseases and Plant Protection, Leibniz Universität Hannover, Herrenhäuser Str. 2, 30419 Hannover, Germany.

In June 2004, wilted tomatoes with no foliar yellowing were observed in Ouègbo, Atlantique District, Benin. The cut tomato stems released whitish bacterial ooze. Longitudinal sections of most stems showed brown vascular discoloration. Read More

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http://dx.doi.org/10.1094/PDIS-93-5-0549BDOI Listing

First Report of Fusarium solani Causing Wilt of Olea europaea in Nepal.

Plant Dis 2009 Feb;93(2):200

Department of Plant Protection-University of Tuscia, Via S. Camillo de Lellis 01100 Viterbo, Italy.

Leaf drop, wilt, and mortality were observed in September of 2007 on approximately 10% of 1- to 2-year-old olive (Olea europaea cv. Leccino) plants shipped from Europe and growing in a nursery in the District of Makwampur, Nepal. Roots of symptomatic and asymptomatic plants were disinfected in 1% NaOCl, cut into 1 cm long pieces, plated on 2% potato dextrose agar, and maintained at 20°C with 14 h of light per day. Read More

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http://dx.doi.org/10.1094/PDIS-93-2-0200ADOI Listing
February 2009

Epidemiology and clinical outcomes of invasive mould infections in Indian intensive care units (FISF study).

J Crit Care 2019 Feb 5;51:64-70. Epub 2019 Feb 5.

Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background And Aim: Due to limited data on invasive mould infections (IMIs) in the intensive care units (ICUs) of developing countries, we ascertain epidemiology and management of IMIs at 11 ICUs across India.

Methods: Consecutive patients with proven or probable/putative IMIs were enrolled during the study period. Subjects were categorized into classical (neutropenia, malignancy, transplant recipients on immunosuppression) and non-classical (chronic obstructive pulmonary disease, diabetes, liver disease and glucocorticoids) risk groups. Read More

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http://dx.doi.org/10.1016/j.jcrc.2019.02.005DOI Listing
February 2019

Long-term creep deformations in colloidal calcium-silicate-hydrate gels by accelerated aging simulations.

J Colloid Interface Sci 2019 Feb 7;542:339-346. Epub 2019 Feb 7.

Physics of AmoRphous and Inorganic Solids Laboratory (PARISlab), Department of Civil and Environmental Engineering, University of California, Los Angeles, CA 90095, USA. Electronic address:

When subjected to a sustained load, jammed colloidal gels can feature some delayed viscoplastic creep deformations. However, due to the long timescale of creep (up to several years), its modeling and, thereby, prediction has remained challenging. Here, based on mesoscale simulations of calcium-silicate-hydrate gels (CSH, the binding phase of concrete), we present an accelerated simulation method-based on stress perturbations and overaging-to model creep deformations in CSH. Read More

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http://dx.doi.org/10.1016/j.jcis.2019.02.022DOI Listing
February 2019

Molecular characterisation and transcriptional regulation of muscle growth regulatory factors myogenin and myogenic factor 6 in the trans-Himalayan cyprinid fish Schizothorax richardsonii.

Comp Biochem Physiol A Mol Integr Physiol 2019 Feb 12. Epub 2019 Feb 12.

ICAR-Directorate of Coldwater Fisheries Research, Bhimtal, Uttarakhand 263136, India.

In vertebrates, myogenic regulatory factors (MRFs) play an important role in muscle growth through the processes of cell determination and differentiation. Herein, we report the molecular characterisation of two MRFs, myogenin (myog) and myogenic factor 6 (myf6) in Indian snow trout Schizothorax richardsonii. The full length mRNA sequence of Srmyog and Srmyf6 was 1437 and 1296 bp, with an ORF of 762 and 720 bp, encoding a putative protein of 253 and 239 amino acids, respectively. Read More

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http://dx.doi.org/10.1016/j.cbpa.2019.02.007DOI Listing
February 2019

Structure of G57W mutant of human γS-crystallin and its involvement in cataract formation.

J Struct Biol 2019 Feb 12. Epub 2019 Feb 12.

Center for Interdisciplinary Sciences, Tata Institute of Fundamental Research, Gopanpally, Hyderabad 500107, India; Department of Chemical Sciences, Tata Institute of Fundamental Research, 1, Homi Bhabha Road, Colaba, Mumbai 400005, India; Indian Institute of Science Education and Research, Berhampur, Odisha 760010, India. Electronic address:

A recently identified mutant of human γS-crystallin, G57W is associated with dominant congenital cataracts, the familial determinate of childhood blindness worldwide. To investigate the structural and functional changes that mediate the effect of this cataract-related mutant to compromise eye lens transparency and cause lens opacification in children, we recently reported complete sequence-specific resonance assignments of γS-G57W using a suite of heteronuclear NMR experiments. As a follow up, we have determined the 3D structure of γS-G57W and studied its conformational dynamics by solution NMR spectroscopy. Read More

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http://dx.doi.org/10.1016/j.jsb.2019.02.003DOI Listing
February 2019

Analysis of RNA polymerase II ubiquitylation and proteasomal degradation.

Methods 2019 Feb 12. Epub 2019 Feb 12.

Mechanisms of Transcription Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address:

Transcribing RNA polymerase II (RNAPII) is decorated by a plethora of post-translational modifications that mark different stages of transcription. One important modification is RNAPII ubiquitylation, which occurs in response to numerous different stimuli that cause RNAPII stalling, such as DNA damaging agents, RNAPII inhibitors, or depletion of the nucleotide pool. Stalled RNAPII triggers a so-called "last resort pathway", which involves RNAPII poly-ubiquitylation and proteasome-mediated degradation. Read More

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http://dx.doi.org/10.1016/j.ymeth.2019.02.005DOI Listing
February 2019

Sida cordifolia accelerates wound healing process delayed by dexamethasone in rats: Effect on ROS and probable mechanism of action.

J Ethnopharmacol 2019 Feb 12. Epub 2019 Feb 12.

Pharmacognosy and Phytochemistry Laboratory, VNS Group of Institutions, Faculty of Pharmacy, VNS Campus, Vidya Vihar, Neelbud, Bhopal, Madhya Pradesh 462044, India. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2018.07.003DOI Listing
February 2019

In vitro anthelmintic effect of biologically synthesized silver nanoparticles on liver amphistome, Gigantocotyle explanatum.

Exp Parasitol 2019 Feb 12. Epub 2019 Feb 12.

Section of Parasitology, Department of Zoology, Aligarh Muslim University, Aligarh, India.

In order to ensure global food security a rationale approach is required to control all those factors which directly or indirectly affect the food productivity. The neglected helminthic diseases alone are responsible for huge economic losses to the agrarian stakeholders. The problem is further compounded by the emerging drug resistance in flukes against the commonly used anthelmintics like triclabendazole. Read More

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http://dx.doi.org/10.1016/j.exppara.2019.02.005DOI Listing
February 2019

Sparse Game Changers Restore Collective Motion in Panicked Human Crowds.

Phys Rev Lett 2019 Feb;122(4):048002

Department of Applied Mechanics, Indian Institute of Technology Madras, Chennai 600036, India.

Using a dynamic variant of the Vicsek model, we show that the emergence of disorder from an orderly moving human crowd is a nonequilibrium first-order phase transition. We also show that this transition can be reversed by modifying the dynamics of a few agents, deemed as game changers. Surprisingly, the optimal placement of these game changers is found to be in regions of maximum local crowd speed. Read More

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http://dx.doi.org/10.1103/PhysRevLett.122.048002DOI Listing
February 2019

Strong Quantum Nonlocality without Entanglement.

Phys Rev Lett 2019 Feb;122(4):040403

Department of Physics and Center for Astroparticle Physics and Space Science, Bose Institute, EN 80, Sector V, Bidhannagar, Kolkata 700091, India.

Quantum nonlocality is usually associated with entangled states by their violations of Bell-type inequalities. However, even unentangled systems, whose parts may have been prepared separately, can show nonlocal properties. In particular, a set of product states is said to exhibit "quantum nonlocality without entanglement" if the states are locally indistinguishable; i. Read More

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http://dx.doi.org/10.1103/PhysRevLett.122.040403DOI Listing
February 2019

Observation of Transverse Λ/Λ[over ¯] Hyperon Polarization in e^{+}e^{-} Annihilation at Belle.

Authors:
Y Guan A Vossen I Adachi K Adamczyk J K Ahn H Aihara S Al Said D M Asner H Atmacan V Aulchenko T Aushev R Ayad V Babu I Badhrees A M Bakich V Bansal P Behera C Beleño M Berger V Bhardwaj B Bhuyan T Bilka J Biswal A Bobrov G Bonvicini A Bozek M Bračko T E Browder L Cao D Červenkov P Chang V Chekelian A Chen B G Cheon K Chilikin K Cho S-K Choi Y Choi D Cinabro S Cunliffe N Dash S Di Carlo J Dingfelder Z Doležal T V Dong Z Drásal S Eidelman D Epifanov J E Fast T Ferber B G Fulsom R Garg V Gaur N Gabyshev A Garmash M Gelb A Giri P Goldenzweig B Golob E Guido J Haba K Hayasaka H Hayashii S Hirose W-S Hou T Iijima K Inami G Inguglia A Ishikawa R Itoh M Iwasaki Y Iwasaki W W Jacobs I Jaegle H B Jeon S Jia Y Jin D Joffe K K Joo T Julius K H Kang T Kawasaki C Kiesling D Y Kim H J Kim J B Kim K T Kim S H Kim K Kinoshita P Kodyš S Korpar D Kotchetkov P Križan R Kroeger P Krokovny T Kuhr R Kulasiri A Kuzmin Y-J Kwon J S Lange I S Lee S C Lee L K Li Y B Li L Li Gioi J Libby D Liventsev M Lubej T Luo M Masuda T Matsuda D Matvienko M Merola H Miyata R Mizuk G B Mohanty H K Moon T Mori R Mussa M Nakao T Nanut K J Nath Z Natkaniec M Nayak M Niiyama N K Nisar S Nishida S Ogawa S Okuno H Ono P Pakhlov G Pakhlova B Pal S Pardi H Park S Paul T K Pedlar R Pestotnik L E Piilonen V Popov E Prencipe A Rabusov A Rostomyan G Russo D Sahoo Y Sakai M Salehi S Sandilya L Santelj T Sanuki V Savinov O Schneider G Schnell C Schwanda R Seidl Y Seino K Senyo O Seon M E Sevior V Shebalin C P Shen T-A Shibata J-G Shiu F Simon A Sokolov E Solovieva M Starič J F Strube M Sumihama T Sumiyoshi W Sutcliffe K Suzuki M Takizawa U Tamponi K Tanida F Tenchini M Uchida T Uglov Y Unno S Uno P Urquijo Y Usov S E Vahsen C Van Hulse R Van Tonder G Varner A Vinokurova V Vorobyev E Waheed B Wang C H Wang M-Z Wang P Wang X L Wang S Watanuki E Widmann E Won H Ye J Yelton J H Yin C Z Yuan Y Yusa Z P Zhang V Zhilich V Zhukova V Zhulanov A Zupanc

Phys Rev Lett 2019 Feb;122(4):042001

J. Stefan Institute, 1000 Ljubljana.

We report the first observation of the spontaneous polarization of Λ and Λ[over ¯] hyperons transverse to the production plane in e^{+}e^{-} annihilation, which is attributed to the effect arising from a polarizing fragmentation function. For inclusive Λ/Λ[over ¯] production, we also report results with subtracted feed-down contributions from Σ^{0} and charm. This measurement uses a dataset of 800. Read More

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https://link.aps.org/doi/10.1103/PhysRevLett.122.042001
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http://dx.doi.org/10.1103/PhysRevLett.122.042001DOI Listing
February 2019
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Nickel(II) and Palladium(II) Complexes Bearing an Unsymmetrical Pyrrole-Based PNN Pincer and Their Norbornene Polymerization Behaviors versus the Symmetrical NNN and PNP Pincers.

Inorg Chem 2019 Feb 15. Epub 2019 Feb 15.

Department of Chemistry , Indian Institute of Technology Kharagpur , Kharagpur , West Bengal , India 721 302.

Unsymmetrical pincers have been shown to be better than the corresponding symmetrical pincers in several catalysis reactions. A new unsymmetrical PNN propincer, 2-(3,5-dimethylpyrazolylmethyl)-5-(diphenylphosphinomethyl)pyrrole (1), was synthesized from pyrrole through Mannich bases in a good yield. In addition, the new byproduct 2-(3,5-dimethylpyrazolylmethyl)-5-(dimethylaminomethyl)- N-(hydroxymethyl)pyrrole was also isolated. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.8b03562DOI Listing
February 2019

Evaluation of ForenSeq™ Signature Prep Kit B on predicting eye and hair coloration as well as biogeographical ancestry by using Universal Analysis Software (UAS) and available web-tools.

Electrophoresis 2019 Feb 15. Epub 2019 Feb 15.

Office of Chief Medical Examiner, Department of Forensic Biology, New York, NY, USA.

This study examined 266 individuals from various populations including African American, East Asian, South Asian, European, and mixed populations to evaluate the ForenSeq™ Signature Prep Kit Primer Mix B. Focus was placed on phenotypic and biogeographical ancestry predictions by Illumina's Universal Analysis Software (UAS). These outcomes were compared to those obtained through web-tools developed at the Erasmus Medical Center (EMC) and available from the Forensic Resource/Reference on Genetics-knowledge base (FROG-kb), as well as to eye color predictions by the 8-plex system. Read More

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http://dx.doi.org/10.1002/elps.201800344DOI Listing
February 2019

Berry transcriptome: Insights into a novel resource to understand development dependent secondary metabolism in Withania Somnifera (Ashwagandha).

Physiol Plant 2019 Feb 15. Epub 2019 Feb 15.

Department of Metabolic and Structural Biology, CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, 226015, India.

Withania somnifera (Ashwagandha) is considered as Rasayana in Indian systems of medicine. This study reports a novel transcriptome of W. somnifera berries, with high depth, quality and coverage. Read More

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http://dx.doi.org/10.1111/ppl.12943DOI Listing
February 2019

Influence of Asian Ethnicities on Short- and Mid-term Outcomes Following Laparoscopic Sleeve Gastrectomy.

Obes Surg 2019 Feb 14. Epub 2019 Feb 14.

Division of General Surgery, National University Health System, 1E, Kent Ridge Road, Singapore, 119228, Singapore.

Purpose: Prevalence of obesity in Asia has been on the increasing trend, with corresponding increase in utilisation of bariatric surgery. The objective of this study was to examine differences in weight loss outcomes following bariatric surgery between Asian ethnicities.

Materials And Methods: A retrospective database review was conducted of patients undergoing primary laparoscopic sleeve gastrectomy between 2009 and 2013 in 14 centres from Singapore, Malaysia, Taiwan, Hong Kong, Japan, Korea, India, Australia, Switzerland, and the USA. Read More

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http://dx.doi.org/10.1007/s11695-019-03716-8DOI Listing
February 2019
3.747 Impact Factor

Bowel Imaging in Children: Part 1.

Indian J Pediatr 2019 Feb 14. Epub 2019 Feb 14.

Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, 110029, India.

The bowel is a challenging abdominal organ to image. The main reason is the variable location, convoluted morphology and motility. A variety of bowel disorders such as congenital, developmental, inflammatory, infectious and neoplastic lesions can affect children and most of them are either unique to this age group or have a distinct clinico-radiological appearance compared to adults. Read More

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http://dx.doi.org/10.1007/s12098-019-02877-9DOI Listing
February 2019

Autophagy inhibition with chloroquine reverts paclitaxel resistance and attenuates metastatic potential in human nonsmall lung adenocarcinoma A549 cells via ROS mediated modulation of β-catenin pathway.

Apoptosis 2019 Feb 14. Epub 2019 Feb 14.

Department of Biotechnology and Dr. B. C. Guha Centre for Genetic Engineering and Biotechnology, University of Calcutta, 35 Ballygunge Circular Road, Ballygunge, Kolkata, West Bengal, 700 019, India.

Paclitaxel is one of the most commonly used drugs for the treatment of nonsmall cell lung cancer (NSCLC). However acquired resistance to paclitaxel, epithelial to mesenchymal transition and cancer stem cell formation are the major obstacles for successful chemotherapy with this drug. Some of the major reasons behind chemoresistance development include increased ability of the cancer cells to survive under stress conditions by autophagy, increased expression of drug efflux pumps, tubulin mutations etc. Read More

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http://dx.doi.org/10.1007/s10495-019-01526-yDOI Listing
February 2019

Hedgehog Signaling Modulates Interleukin-33-Dependent Extrahepatic Bile Duct Cell Proliferation in Mice.

Hepatol Commun 2019 Feb 11;3(2):277-292. Epub 2018 Dec 11.

Department of Internal Medicine University of Michigan Ann Arbor MI.

Hedgehog (HH) signaling participates in hepatobiliary repair after injury and is activated in patients with cholangiopathies. Cholangiopathies are associated with bile duct (BD) hyperplasia, including expansion of peribiliary glands, the niche for biliary progenitor cells. The inflammation-associated cytokine interleukin (IL)-33 is also up-regulated in cholangiopathies, including cholangiocarcinoma. Read More

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http://dx.doi.org/10.1002/hep4.1295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357834PMC
February 2019

Immune checkpoint inhibitors: Real-world experience from India in advanced solid cancers that have progressed on chemotherapy.

South Asian J Cancer 2019 Jan-Mar;8(1):65-68

Department of Medical Oncology, Max Super Speciality Hospital, New Delhi, India.

Context: The immune checkpoint inhibitors (ICIs) nivolumab and pembrolizumab have shown dramatic efficacy with low toxicity in international studies of advanced solid cancers. No published Indian experience with ICIs exist other than isolated case reports.

Aims: The aim of this study is to evaluate real-world data about the efficacy and toxicity of ICIs in advanced solid cancers among Indian patients who have progressed on one or more prior lines of chemotherapy. Read More

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http://dx.doi.org/10.4103/sajc.sajc_167_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348784PMC
February 2019

Safety and efficacy of nimotuzumab with concurrent chemoradiotherapy in unresectable locally advanced squamous cell carcinoma of head and neck: An Indian rural hospital experience.

South Asian J Cancer 2019 Jan-Mar;8(1):52-56

Department of Radiation Oncology, NSCB Medical College and Government Hospital, Jabalpur, Madhya Pradesh, India.

Context: Nimotuzumab is the only anti-epidermal growth factor receptor monoclonal antibody which can be safely added to concurrent chemoradiotherapy (CRT) to improve efficacy in the management of unresectable, locally advanced squamous cell carcinoma of head and neck (LA-SCCHN). However, the evidence available on this is limited.

Aims: We retrospectively investigated efficacy and safety of nimotuzumab when combined with chemoradiation for LA-SCCHN. Read More

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http://dx.doi.org/10.4103/sajc.sajc_76_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348788PMC
February 2019

Chronic lymphocytic leukemia with deletion 17p: An Indian scenario.

South Asian J Cancer 2019 Jan-Mar;8(1):40

Department of Lab Oncology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.4103/sajc.sajc_287_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348775PMC
February 2019

Pressurized intraperitoneal aerosol chemotherapy procedure for nonresectable peritoneal carcinomatosis: First Indian study.

South Asian J Cancer 2019 Jan-Mar;8(1):27-30

Department of Surgical Oncology, Manipal Hospital, Bengaluru, Karnataka, India.

Background: Peritoneal carcinomatosis (PC) is a common evolution of abdominal cancers and is associated with poor prognosis. A few selected patients have option of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy, but majority who are not eligible for curative approach can undergo pressurized intraperitoneal aerosol chemotherapy (PIPAC). It is an emerging field of research with major therapeutic potential. Read More

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http://journal.sajc.org/text.asp?2019/8/1/27/250100
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http://dx.doi.org/10.4103/sajc.sajc_92_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348786PMC
February 2019
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Practice patterns and outcomes with the use of regorafenib in metastatic colorectal cancer: Results from the Regorafenib in Metastatic colorectal cancer - An Indian exploratory analysis study.

South Asian J Cancer 2019 Jan-Mar;8(1):22-26

Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Background: Regorafenib is considered a standard of care as third-line therapy in metastatic colorectal cancers (mCRCs).

Materials And Methods: The study was based on a computerized clinical data form sent to oncologists across the country for entry of anonymized patient data. The data entry form was conceived and generated by the coordinating center's (Tata Memorial Hospital) gastrointestinal medical oncologists and disseminated through personal contacts at academic conferences as well as through E-mail to various oncologists across India. Read More

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http://dx.doi.org/10.4103/sajc.sajc_173_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348777PMC
February 2019

Treatment of advanced nonsmall cell lung cancer: First line, maintenance and second line - Indian consensus statement update.

Authors:
Kumar Prabhash

South Asian J Cancer 2019 Jan-Mar;8(1):1-17

Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

The management of advanced nonsmall cell lung cancer (NSCLC) patients is becoming increasingly complex with the identification of driver mutations/rearrangements and development/availability of appropriate targeted therapies. In 2017, an expert group of medical oncologists with expertise in treating lung cancer used data from published literature and experience to arrive at practical consensus recommendations on treatment of advanced NSCLC for use by the community oncologists. This was published subsequently in the Indian Journal of Cancer with a plan to be updated annually. Read More

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http://dx.doi.org/10.4103/sajc.sajc_227_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348782PMC
February 2019

Erratum: Lean Metabolic Syndrome: A Concept or a Reality?

Authors:

Indian J Endocrinol Metab 2018 Nov-Dec;22(6):868

[This corrects the article on p. 303 in vol. 22, PMID: 30090719. Read More

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http://dx.doi.org/10.4103/2230-8210.246859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330855PMC
February 2019

Erratum: Occurrence of Subacute Thyroiditis following Influenza Vaccination.

Authors:

Indian J Endocrinol Metab 2018 Nov-Dec;22(6):867

[This corrects the article on p. 713 in vol. 22, PMID: 30294587. Read More

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http://dx.doi.org/10.4103/2230-8210.246858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330849PMC
February 2019

Erratum: Effect of Physical Activity during Pregnancy on Gestational Diabetes Mellitus.

Authors:

Indian J Endocrinol Metab 2018 Nov-Dec;22(6):866

[This corrects the article on p. 661 in vol. 22, PMID: 30294578. Read More

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http://dx.doi.org/10.4103/2230-8210.246857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330856PMC
February 2019