256,706 results match your criteria Indian journal of dermatology venereology and leprology[Journal]


Influence of alkali treatment on physicochemical, pasting, morphological and structural properties of mango kernel starches derived from Indian cultivars.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Department of Food Engineering and Technology, Sant Longowal Institute of Engineering and Technology, Longowal, Punjab, India. Electronic address:

Present investigation was aimed to characterize the influence of alkali treatment on physicochemical, pasting, morphological and structural properties of mango kernel starches from three cultivars viz. Safeda, Chausa, Dussheri when treated with 0.1, 0. Read More

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December 2018

Graft copolymeric flocculant using functionalized starch towards treatment of blast furnace effluent.

Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.

Department of Applied Chemistry, Indian Institute of Technology (ISM), Dhanbad 826004, India. Electronic address:

Herein, a novel binary graft copolymeric flocculant [St-g-(PAAm-co-PMETAC)] has been developed using starch, polyacrylamide (PAAm) and poly (2-methacryloyloxy ethyl trimethyl ammonium chloride) (PMETAC). The copolymer has been synthesised by grafting of PAAm and PMETAC chains on starch backbone using free radical polymerization. FTIR and H NMR spectral analyses have been used for structural confirmation of developed copolymer. Read More

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December 2018
2 Reads

Fluorescence polarization assay: Diagnostic evaluation for porcine brucellosis.

J Microbiol Methods 2018 Dec 3. Epub 2018 Dec 3.

Indian Council Agricultural Research-National Institute of Veterinary Epidemiology and Disease Informatics, Yelahanka, Bengaluru 560064, India. Electronic address:

Brucellosis in pigs, caused by the bacterium Brucella suis, is an important zoonotic infection. In the present study, fluorescence polarization assay (FPA) was standardized and compared with indirect enzyme linked immunosorbent assay (iELISA) and competitive ELISA (cELISA) for diagnosis of porcine brucellosis. Test performances were evaluated using representative panel (n = 100), samples from swine brucellosis outbreak (n = 300), samples from brucellosis suspected animals (n = 291) and sera samples from apparently healthy animals (n = 1121). Read More

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December 2018
3 Reads

PEG-grafted phospholipids in vesicles: Effect of PEG chain length and concentration on mechanical properties.

Chem Phys Lipids 2018 Dec 3. Epub 2018 Dec 3.

Department of Chemical Engineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India. Electronic address:

Incorporation of low molecular weight poly-ethylene glycol (PEG) - grafted phospholipids in vesicle bilayers is known to increase the circulation time of liposomal drug delivery vehicles. Mechanical properties of giant unilamellar DPPC vesicles containing varying concentrations of DSPE-PEG (PEG MW: 550, 1000 and 2000) were measured by micropipette aspiration assay or osmotic swelling. While the area compressibility modulus did not change significantly, the bending modulus and water permeability of the bilayer was found to increase with increasing mole fraction of DSPE-PEG. Read More

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December 2018

Visceral leishmaniasis: Spatiotemporal heterogeneity and drivers underlying the hotspots in Muzaffarpur, Bihar, India.

PLoS Negl Trop Dis 2018 Dec 6;12(12):e0006888. Epub 2018 Dec 6.

Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Background: Despite the overall decrease in visceral leishmaniasis (VL) incidence on the Indian subcontinent, there remain spatiotemporal clusters or 'hotspots' of new cases. The characteristics of these hotspots, underlying transmission dynamics, and their importance for shaping control strategies are not yet fully understood and are investigated in this study for a VL endemic area of ~100,000 inhabitants in Bihar, India between 2007-2015.

Methodology/principal Findings: VL incidence (cases/10,000/year) dropped from 12. Read More

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December 2018

Age trends in asymptomatic and symptomatic Leishmania donovani infection in the Indian subcontinent: A review and analysis of data from diagnostic and epidemiological studies.

PLoS Negl Trop Dis 2018 Dec 6;12(12):e0006803. Epub 2018 Dec 6.

Zeeman Institute, University of Warwick, Coventry, United Kingdom.

Background: Age patterns in asymptomatic and symptomatic infection with Leishmania donovani, the causative agent of visceral leishmaniasis (VL) in the Indian subcontinent (ISC), are currently poorly understood. Age-stratified serology and infection incidence have been used to assess transmission levels of other diseases, which suggests that they may also be of use for monitoring and targeting control programmes to achieve elimination of VL and should be included in VL transmission dynamic models. We therefore analysed available age-stratified data on both disease incidence and prevalence of immune markers with the aim of collating the currently available data, estimating rates of infection, and informing modelling and future data collection. Read More

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December 2018
2 Reads

Reinvestigating the status of malaria parasite (Plasmodium sp.) in Indian non-human primates.

PLoS Negl Trop Dis 2018 Dec 6;12(12):e0006801. Epub 2018 Dec 6.

TE-11, Centre for Ecological Sciences, Indian Institute of Sciences, Bangalore, India.

Many human parasites and pathogens have closely related counterparts among non-human primates. For example, non-human primates harbour several species of malaria causing parasites of the genus Plasmodium. Studies suggest that for a better understanding of the origin and evolution of human malaria parasites it is important to know the diversity and evolutionary relationships of these parasites in non-human primates. Read More

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December 2018

Structural basis for neutralization of cytotoxic abrin by monoclonal antibody D6F10.

FEBS J 2018 Dec 6. Epub 2018 Dec 6.

Department of Physics, Indian Institute of Science, Bengaluru, 560012, India.

Abrin, an extremely cytotoxic Type-II ribosome inactivating protein (RIP), is a potential bio-warfare agent. Abrin A-chain (ABA) depurinates an adenosine of sarcin-ricin loop (SRL) from eukaryotic 28S rRNA thereby arresting protein synthesis and leading to cell death. Monoclonal antibody (mAb) D6F10 is the only known antibody that neutralizes ABA's activity in cell-free systems as well as abrin's toxicity in vitro and in vivo. Read More

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December 2018

Hexameric assembly of the AAA+ protein McrB is necessary for GTPase activity.

Nucleic Acids Res 2018 Dec 6. Epub 2018 Dec 6.

Division of Biology, Indian Institute of Science Education and Research, Pune 411008, India.

McrBC is one of the three modification-dependent restriction enzymes encoded by the Escherichia coli K12 chromosome. Amongst restriction enzymes, McrBC and its close homologues are unique in employing the AAA+ domain for GTP hydrolysis-dependent activation of DNA cleavage. The GTPase activity of McrB is stimulated by the endonuclease subunit McrC. Read More

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December 2018
2 Reads

Whole-genome sequence of the oriental lung fluke Paragonimus westermani.

Gigascience 2018 Dec 6. Epub 2018 Dec 6.

The University of Queensland Diamantina Institute, Brisbane, QLD, Australia.

Background: Foodborne infections caused by lung flukes of the genus Paragonimus are a significant and widespread public health problem in tropical areas. Around 50 Paragonimus species have been reported to infect animals and humans, but Paragonimus westermani is responsible for the bulk of human disease. Despite their medical and economic importance, no genome sequence for any Paragonimus species is available. Read More

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December 2018
2 Reads

Correction: A synthetic study toward the core structure of (-)-apicularen A.

Org Biomol Chem 2018 Dec 6. Epub 2018 Dec 6.

Organic Synthesis and Process Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007, India.

Correction for 'A synthetic study toward the core structure of (-)-apicularen A' by Tapas R. Pradhan et al., Org. Read More

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December 2018

Understanding the role of co-surfactants in microemulsions on the growth of copper oxalate using SAXS.

Phys Chem Chem Phys 2018 Dec 6. Epub 2018 Dec 6.

Institute of Nano-Science and Technology, Habitat Centre, Phase - 10, Sector - 64, Mohali-160062, India.

This study is an effort to understand the mechanism of the effect of the chain length of co-surfactants on the growth of copper oxalate inside the core of reverse micelles using small angle X-ray scattering (SAXS). In this study, we have used two different kinds of co-surfactants viz. 1-butanol (C4) and 1-octanol (C8) for the formation of the microemulsions. Read More

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December 2018
1 Read

Synthesis of novel derivatives of 7,8-dihydro-6H-imidazo[2,1-b][1,3]benzothiazol-5-one and their virus-inhibiting activity against influenza A virus.

Arch Pharm (Weinheim) 2018 Dec 6. Epub 2018 Dec 6.

Fluoro and Agrochemicals Division (Organic Chemistry Division-II), CSIR - Indian Institute of Chemical Technology, Hyderabad, India.

Influenza remains a highly pathogenic and hardly controlled human infection. The ability of selecting drug-resistant variants necessitates the search and development of novel anti-influenza drugs. Herein, we describe the synthesis and evaluation of a series of novel 2-substituted 7,8-dihydro-6H-imidazo[2,1-b][1,3]benzothiazol-5-ones 3a-k for their virus-inhibiting activity against influenza A virus. Read More

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December 2018
1 Read

Effect of preservation methods on tensile properties of human femur-ACL-tibial complex (FATC) - a cadaveric study on male subjects.

Acta Bioeng Biomech 2018 ;20(4):31-42

Centre for Biomedical Engineering, Indian Institute of Technology (IIT) Delhi, New Delhi, India.

Purpose: Deep freezing and storing in formalin are some of the common techniques of human tissue preservation. However, the preservation modes affect the biomechanical properties of the tissues. In this work, the effects of the above-stated preservation tech- niques are compared with that of fresh cadaveric samples. Read More

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January 2018

Variable sialic acid content in milk of Indian cattle and buffalo across different stages of lactation.

J Dairy Res 2018 Dec 6:1-4. Epub 2018 Dec 6.

ICAR- National Bureau of Animal Genetic Resources,Karnal 132 001, Haryana,India.

The aim of this Research Communication was to contribute to the knowledge of milk sialic acid concentration of bovines with specific focus on India. Sialic acids (SA) are important constituents of mammalian milks. Buffaloes are the main milk producing species in India, therefore, our research focused on both cow and buffalo. Read More

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December 2018

Sense of Smell: Structural, Functional, Mechanistic Advancements and Challenges in Human Olfactory Research.

Curr Neuropharmacol 2018 Dec 5. Epub 2018 Dec 5.

Department of Applied Science, Indian Institute of Information Technology, Allahabad, Uttar Pradesh. India.

Olfaction, the sense of smell detects and discriminate odors as well as social cues which influence our innate responses. The olfactory system in human beings is found to be weak as compare to other animals; however, it seems to be very precise. It can detect and discriminate millions of chemical moieties (odorants) even in minuscule quantities. Read More

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December 2018

Immune Associated LncRNAs Identify Novel Prognostic Subtypes of Renal Clear Cell Carcinoma.

Mol Carcinog 2018 Dec 5. Epub 2018 Dec 5.

Department of Biosciences and Bioengineering, Indian Institute of Technology Dharwad, Dharwad, Karnataka, 580011.

Kidney Renal Clear Cell Carcinoma (KIRC) is a significant cause of cancer-related deaths. Here, we aim to identify the LncRNAs associated with the immune system and characterise their clinical utility in KIRC. A total of 504 patients' data was used from TCGA-GDC. Read More

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December 2018
1 Read
4.808 Impact Factor

Development and validation of a rapid and sensitive UPLC-MS/MS assay for the quantification of tofacitinib in human plasma.

Biomed Chromatogr 2018 Dec 5:e4458. Epub 2018 Dec 5.

Bioanalytical Department, Alkem Laboratories Ltd., Lower Parel, Mumbai, India.

A highly sensitive, selective and rapid ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method has been developed for the quantification of a Janus kinase (JAK) inhibitor, tofacitinib (TOF). The assay employed liquid-liquid extraction with methyl-tert butyl ether to extract tofacitinib and tofacitinib-13C3 15N (as internal standard) from human plasma. The samples were analyzed on UPLC BEH C18 (50 × 2. Read More

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December 2018

ATP-dependent membrane remodeling links EHD1 functions to endocytic recycling.

Nat Commun 2018 Dec 5;9(1):5187. Epub 2018 Dec 5.

Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune, 411008, Maharashtra, India.

Endocytic and recycling pathways generate cargo-laden transport carriers by membrane fission. Classical dynamins, which generate transport carriers during endocytosis, constrict and cause fission of membrane tubes in response to GTP hydrolysis. Relatively, less is known about the ATP-binding Eps15-homology domain-containing protein1 (EHD1), a dynamin family member that functions at the endocytic-recycling compartment. Read More

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December 2018

Vitamin D status in Kancheepuram District, Tamil Nadu, India.

BMC Public Health 2018 Dec 5;18(1):1345. Epub 2018 Dec 5.

SRM Institute of Gastroenterology, Hepatobiliary Sciences & Transplantation, SIMS Hospital, Jawaharlal Nehru Road, Vadapalani, Chennai, Tamil Nadu, India.

Background: Vitamin D has multifarious roles in maintenance of health and prevention of disease. The present study was undertaken to assess the vitamin D status of a rural adult south Indian population and to identify its associations with socioeconomic status and cultural practices.

Methods: Between June 2015 and July 2016, 424 healthy adults residing in Kattankulathur block in Tamil Nadu, India, provided venous blood samples and answered questions by personal interview. Read More

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December 2018
1 Read

'They love me, but they don't understand me': Family support and stigmatisation of mental health service users in Gujarat, India.

Int J Soc Psychiatry 2018 Dec 5:20764018816344. Epub 2018 Dec 5.

7 Centre for Mental Health Law and Policy, Indian Law Society, Pune, India.

Background:: Family life is a near-universal condition and a fundamental human right. It can also have a significant impact on mental health, including recovery from mental health conditions. In India, families play a considerable role, representing a source of social, cultural, religious and, often, financial support. Read More

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December 2018
1 Read

Self-silencing and women's health: A review.

Int J Soc Psychiatry 2018 Dec 5:20764018814271. Epub 2018 Dec 5.

Department of Humanities and Social Sciences, Indian Institute of Technology Kanpur, Kanpur, India.

The connection between gender and health has intrigued health professionals in the last few decades. Silencing-the-self theory has brought a considerable clarity in this matter. After around three decades of the theory, the literature related to the theory has immensely flourished and has covered different branches of psychology. Read More

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December 2018
5 Reads

Assessment of the Inhibitory Effects of Ficin-hydrolyzed Gelatin Derived from Squid (Uroteuthis duvauceli) on Breast Cancer Cell Lines and Animal Model.

Iran J Allergy Asthma Immunol 2018 Oct 14;17(5):436-452. Epub 2018 Oct 14.

Department of Marine Science and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran.

Marine novel natural products have been applied for cancer therapy. Enzyme-digested gelatin hydrolysates have proven to serve as promising sources of potent biologically active peptides. Potential anti-breast cancer properties of the extracted Ficin-digesterd gelatin hydrolysate from Indian squid (Uroteuthis duvauceli) was extensively characterized by cellular and animal models. Read More

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October 2018

Gestational Diabetes Mellitus in a Tertiary Care Hospital of Kolkata, India: Prevalence, Pathogenesis and Potential Disease Biomarkers.

Exp Clin Endocrinol Diabetes 2018 Dec 3. Epub 2018 Dec 3.

Department of Life Sciences, Presidency University, Kolkata, India.

Aims: Prevalence of gestational diabetes mellitus (GDM) may vary across a country like India. Risk factors and disease-pathogenesis were also not fully elucidated. This study aimed to examine prevalence of GDM among pregnant women visiting antenatal clinic of a tertiary-care hospital of Kolkata, India; possible mechanism of disease pathogenesis and potency of associated parameters as disease biomarkers were also explored. Read More

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December 2018
11 Reads

Sonocatalytic reduction of nitrate using magnetic layered double hydroxide: Implications for removal mechanism.

Chemosphere 2018 Nov 27;218:799-809. Epub 2018 Nov 27.

Department of Environmental Engineering, Kwangwoon University, 20 Kwangwoon-Ro, Nowon-Gu, Seoul, 01897, Republic of Korea. Electronic address:

In this study, magnetic layered double hydroxides (mag-LDHs) were synthesized through compositing magnetite with three different metals (Mg, Cu and Al) under ultrasound (US, 100 kHz frequency and 50 W power). For the first time, mag-LDHs were applied to sonocatalytic reduction of nitrate (NO) and the reduction mechanism were determined by conducting kinetic tests and various spectroscopic analyses. Based on the kinetic data, NO reduction and the selectivity for N highly depends on the ratio between Mg/Al, solution pH and sonication frequency. Read More

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November 2018

Essential oils: from prevention to treatment of skin cancer.

Drug Discov Today 2018 Nov 30. Epub 2018 Nov 30.

Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, India; Indian Institute of Technology Madras, Chennai - 600 036, India. Electronic address:

The increasing incidence of cutaneous malignancies signifies the need for multiple treatment options. Several available reviews have emphasized the potential role of various botanical extracts and naturally occurring compounds as anti-skin-cancer agents. Few studies relate to the role of chemoprevention and therapeutic activity of essential oils (EOs) and EO components. Read More

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November 2018

Evaluation of imidazole and its derivative against Newcastle disease virus infection in chicken: A drug repurposing approach.

Virus Res 2018 Nov 30. Epub 2018 Nov 30.

Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, 781039, Assam, India. Electronic address:

Despite recent progress in vaccination options, Newcastle disease virus (NDV) stands a severe global epidemic and economic burden. It is difficult to control NDV with vaccination alone due to its evolving genetic variability; therefore, an effective therapeutic must target to resist its replication and further evolution. Drug repurposing is a practical and economical method to develop therapeutics against pathogenic organisms. Read More

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November 2018

Endocardial transvenous pacing in patients with surgically palliated univentricular hearts: A review on different techniques, problems and management.

Indian Pacing Electrophysiol J 2018 Nov 30. Epub 2018 Nov 30.

Department of Pediatric Cardiology, Madras Medical Mission, Chennai, India. Electronic address:

Fontan surgery and its modifications have improved survival in various forms of univentricular hearts. A regular atrial rhythm with atrioventricular synchrony is one of the most important prerequisite for the long-term effective functioning of this preload dependent circulation. A significant proportion of these survivors need various forms of pacing for bradyarrhythmias, often due to sinus nodal dysfunction and sometimes due to atrioventricular nodal block. Read More

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November 2018

Short-Term Incidence of Sequelae of HCV Infection Among Medicaid Beneficiaries in Oregon.

Public Health Rep 2018 Dec 3:33354918813552. Epub 2018 Dec 3.

1 Oregon Public Health Division, Acute and Communicable Disease Prevention, Oregon Health Authority, Portland, OR, USA.

Objectives:: Given the known high morbidity and mortality of hepatitis C virus (HCV) infection in Oregon, we sought to develop a practical method of estimating the severe sequelae of HCV infection among Medicaid beneficiaries in Oregon.

Methods:: We assembled a retrospective cohort that identified all Oregon Medicaid beneficiaries with HCV infection enrolled for at least 1 year during 2009-2013. We linked this cohort to 3 data sets to identify HCV-related deaths, cases of hepatocellular carcinoma (HCC), and first hospitalizations for advanced liver disease (ALD). Read More

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December 2018

Geophagy among nonhuman primates: A systematic review of current knowledge and suggestions for future directions.

Am J Phys Anthropol 2018 Dec 3. Epub 2018 Dec 3.

Department of Anthropology, Institute for Policy Research, Northwestern University, Evanston, Illinois.

Objectives: Geophagy, the intentional consumption of earth, is widely practiced among humans and other mammals, but its causes are not well understood. Given the growing number of reports of geophagy among nonhuman primates (NHP), we sought to (1) advance and codify our understanding of the patterns and functional and evolutionary significance of geophagy among NHP and (2) provide a research agenda for a more unified approach to its study.

Methods: We systematically reviewed all available literature on NHP geophagy, extracted available data on taxa, geography, climate, diet, sex, age-class, reproductive status, and the characteristics of the earth. Read More

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December 2018
2 Reads

Pyrazole appended quinoline-BODIPY based arene ruthenium complexes: their anticancer activity and potential applications in cellular imaging.

Dalton Trans 2018 Dec 3. Epub 2018 Dec 3.

Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi - 221005, UP, India.

Synthesis of an entirely new series of arene ruthenium complexes [Ru(η6-C6H6)(L1)Cl]PF6, (1), [Ru(η6-C10H14)(L1)Cl]PF6 (2), [Ru(η6-C6H6)(L2)Cl]PF6 (3) and [Ru(η6-C10H14)(L2)Cl]PF6 (4) involving 5-[2-(1H-pyrazol-1-yl)quinoline]-BODIPY (L1) and 5-[6-methoxy-2-(1H-pyrazol-1-yl)quinoline]-BODIPY (L2) was described. The ligands and complexes were thoroughly characterized by various physicochemical techniques and the structures of L1, 1 and 4 were determined by X-ray single crystal analyses. Photo-/ and electrochemical property, DNA binding, cytotoxicity, cellular uptake and apoptotic studies on 1-4 were performed by various methods, while singlet oxygen-mediated cytotoxicity via photo-irradiation by visible light was supported by 1,3-diphenylisobenzofuran titration studies. Read More

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December 2018

Multiple Variations at the Base of an Adult Skull: Implications in Radiology and Skull Base Surgery.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Melaka Manipal Medical College (Manipal Campus), Manipal Academy of Higher Education, Manipal, India.

Knowledge of variations at the base of the skull may be important for academic, anthropological, forensic, and clinical purposes, especially in computed tomography and magnetic resonance imaging and while performing safe radical surgery. This report presents multiple variations at the base of an adult Indian skull. The variations noted include the presence of foramen of Civinini bilaterally, absence of carotid canal on the left side, reduced size of foramen lacerum on the left side, presence of petro-occipital foramen bilaterally, asymmetry between the jugular fossae, and asymmetrical occipital condyles. Read More

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November 2018

Cancer trends and burden in India - Authors' response.

Lancet Oncol 2018 Dec;19(12):e664

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA; Public Health Foundation of India, Gurugram 122002, National Capital Region, India. Electronic address:

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December 2018
24.690 Impact Factor

Peripheral nerve targeting by procaine-conjugated ribavirin-loaded dual drug nanovesicle.

Nanomedicine (Lond) 2018 Dec 3. Epub 2018 Dec 3.

Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, West Bengal, India.

Aim: Procaine that is able to reach the peripheral nervous system (PNS) was conjugated as a ligand with lipid nanovesicle and loaded with ribavirin (a broad spectrum antiviral drug incapable of entering the PNS on its own) to target the PNS with a dual-drug effect.

Materials & Methods: Different physicochemical characterizations, γ-scintigraphy and electromyography of the developed nanovesicle were conducted.

Results: Marked capability of the optimized radiolabeled formulation to target PNS was observed in rats. Read More

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December 2018

Approaching Materials with Atomic Precision Using Supramolecular Cluster Assemblies.

Acc Chem Res 2018 Dec 3. Epub 2018 Dec 3.

DST Unit of Nanoscience (DST UNS) and Thematic Unit of Excellence (TUE), Department of Chemistry , Indian Institute of Technology Madras , Chennai 600 036 , India.

Supramolecular chemistry is a major area of chemistry that utilizes weaker non-covalent interactions between molecules, including hydrogen bonding, van der Waals, electrostatic, π···π, and C-H···π interactions. Such forces have been the basis of several molecular self-assemblies and host-guest complexes in organic, inorganic, and biological systems. Atomically precise nanoclusters (NCs) are materials of growing interest that display interesting structure-property correlations. Read More

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December 2018

Correlation of Abrin-Mediated Inhibition of Protein Synthesis and Apoptosis.

IUBMB Life 2018 Dec 2. Epub 2018 Dec 2.

Department of Biochemistry, Indian Institute of Science, Bangalore, Karnataka, India.

The plant toxin, abrin, a type-II ribosome inactivating protein, is extremely lethal, the human fatal dose being ~1 μg/kg body weight. Abrin has been classified as an agent for bioterrorism, which is of concern. Conversely, the high toxic property of abrin has been employed in generating immunotoxins, whereas its toxin moiety is conjugated to cell surface marker-specific antibodies for cell-targeted killing. Read More

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December 2018

Fundamentals, challenges, and nanomedicine-based solutions for ocular diseases.

Wiley Interdiscip Rev Nanomed Nanobiotechnol 2018 Dec 3:e1548. Epub 2018 Dec 3.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, India.

The eye consists of sensitive, compactly adjoined tissue structures which act as strong physical (static) and physiological (dynamic) barriers that prevent entry of foreign bodies into the eye. Together, these barriers reduce the bioavailability of topically and intraocularly administered medicaments thus demanding frequent drug administration for the treatment of chronic eye diseases. Hence, development of drug delivery systems (DDS) that can be retained in ocular tissues for longer durations can help to reduce the frequency of drug administration, whereas, delivery systems that traverse through ocular barriers may offer higher bioavailability of administered drugs to otherwise inaccessible ocular tissues. Read More

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December 2018

Consanguinity and its association with visual impairment in southern India: the Pavagada Pediatric Eye Disease Study 2.

J Community Genet 2018 Dec 1. Epub 2018 Dec 1.

University of Minnesota Medical School, Duluth campus, Minneapolis, MN, USA.

To determine the association of consanguinity with the occurrence of genetically transmitted eye diseases in rural and urban populations in Pavagada and Madhugiri taluks, Karnataka state, south India. This study was part of a population based cross-sectional prevalence survey, "The Pavagada pediatric eye disease study 2." As a part of the demographic data, trained investigators collected information on consanguinity from the parents of children identified for the study. Read More

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December 2018

Cognizance and social attitudes regarding tobacco control laws in and around educational institutions of Nellore city, India.

J Educ Health Promot 2018 29;7:125. Epub 2018 Oct 29.

Department of Periodontics, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.

Introduction: Indian national law namely Cigarettes and Other Tobacco Products Act (COTPA) exists since 2003 and aims at protecting all the people in our country, but smoking is still prevalent among people. This study was aimed to assess awareness, attitudes, and practices regarding prohibition of sale of tobacco products near educational institutions of Nellore city, India.

Materials And Methods: A descriptive cross-sectional study was conducted in degree colleges of Nellore city of Andhra Pradesh. Read More

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October 2018

Status of - fusion in prostate cancer patients from India: correlation with clinico-pathological details and Met160Val polymorphism.

Prostate Int 2018 Dec 26;6(4):145-150. Epub 2018 Mar 26.

Research and Development, SRL Ltd, Mumbai 400 062, India.

Background: Prostate cancer (PCa) shows considerable clinical heterogeneity that has been primarily attributed to variable molecular alterations. - fusion is one such molecular subtype that has been associated with predominantly poor prognosis. More recently, a single nucleotide polymorphism (SNP) in the gene rs12329760 C>T (Met160Val) has been shown to positively correlate with the fusion status and also to be associated with increased risk for PCa. Read More

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December 2018

and Mahon Brothers: Two Laymen "Physicians" of Hôpital Saint-Louis, Paris.

Indian Dermatol Online J 2018 Nov-Dec;9(6):481-483

Consultant Dermatologist, "Pranab", Ismile, Asansol, West Bengal, India.

In the early and mid-nineteenth century Europe, ringworm of the scalp was a vexing problem. It affected children in such numbers that the famous Hôpital Saint-Louis of Paris had a separate Tinea School. Before advent of radiation method of epilation, painful method of peeling was the mainstay of management. Read More

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December 2018

Brown Shadow in Lichen Nitidus: A Dermoscopic Marker!

Indian Dermatol Online J 2018 Nov-Dec;9(6):479-480

DNB, Consultant, Rita Skin Foundation, Kolkata, West Bengal, India.

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December 2018

Dermoscopy of Striae Rubrae.

Indian Dermatol Online J 2018 Nov-Dec;9(6):477-478

Skinnocence: The Skin Clinic, Gururgram, Haryana, India.

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December 2018

Dermoscopy of Juvenile Circumscribed Pityriasis Rubra Pilaris.

Indian Dermatol Online J 2018 Nov-Dec;9(6):474-476

Department of Dermatology and Venereology, Pramukhswami Medical College, Karamsad, Gujarat, India.

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December 2018

Vulvar Extramammary Paget's Disease Secondary to Urothelial Carcinoma Presenting with a Small Painful Erosion of the Vulva.

Indian Dermatol Online J 2018 Nov-Dec;9(6):471-473

Department of Dermatology, National Cheng Kung University Hospital, Tainan, Taiwan.

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December 2018

Exclusive Facial Actinic Porokeratosis.

Indian Dermatol Online J 2018 Nov-Dec;9(6):469-470

Department of Dermatology, Sri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital, Dharwad, Karnataka, India.

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December 2018
1 Read

Blistering and Mottled Pigmentation in a Young Male.

Indian Dermatol Online J 2018 Nov-Dec;9(6):467-468

Department of Pathology, AIIMS, Jodhpur, Rajasthan, India.

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December 2018

Secukinumab in Generalized Pustular Psoriasis.

Indian Dermatol Online J 2018 Nov-Dec;9(6):464-466

Consultant Dermatologist, Apollo Hospitals, Greams Road, Chennai, Tamil Nadu, India.

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December 2018

Pseudo Acne Fulminans: An Under Recognized Entity.

Indian Dermatol Online J 2018 Nov-Dec;9(6):462-464

Department of Dermatology, R.N.T. Medical College, Udaipur, Rajasthan, India.

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December 2018

Periorbital Ecchymosis Secondary to Severe Coughing- A Valsalva Associated Phenomenon.

Indian Dermatol Online J 2018 Nov-Dec;9(6):461-462

Department of Dermatology, Venereology and Leprosy, Pandit Bhagwat Dayal Sharma Post graduate Institute of Medical Sciences, Rohtak, Haryana, India.

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December 2018