257,188 results match your criteria Indian Journal of Science and Technology [Journal]


Prolonging food shelf-life by dual actives release from multi-layered polymer particles.

Colloids Surf B Biointerfaces 2018 Dec 4;175:281-290. Epub 2018 Dec 4.

Department of Materials Science and Engineering, Indian Institute of Technology, Delhi, 110016, India. Electronic address:

Biodegradable polymer based 'controlled release packaging' technology has ability to release packaging actives in controlled manner to prolong the food shelf-life. Currently available systems are not sufficiently capable of releasing multiple actives in sustainable fashion. Hence, the purpose of this study was to develop dual actives (antioxidant and antibacterial) loaded multilayered microparticles in one step and to release them at rates suitable for long-term inhibition of bacterial growth as well as lipid oxidation in food. Read More

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December 2018

Antitumor effect of chondroitin AC lyase (PsPL8A) from Pedobacter saltans on melanoma and fibrosarcoma cell lines by in vitro analysis.

Pharmacol Rep 2018 Oct 25;71(1):167-174. Epub 2018 Oct 25.

Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, India. Electronic address:

Background: PGs are involved in cellular communication and cancer biology. The role of CS in melanoma and fibrosarcoma cell lines was explored by using chondroitin AC lyase (PsPL8A).

Methods: The proliferation of mouse fibroblast L929, human melanoma (SK-Mel 28) and fibrosarcoma (HT-1080) cell lines after treatment with chondroitin AC lyase (PsPL8A) was studied by MTT assay. Read More

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October 2018

Comparison and implementation of different control strategies for improving production of rHSA using Pichia pastoris.

J Biotechnol 2018 Dec 11. Epub 2018 Dec 11.

Department of Chemical Engineering, Indian Institute of Technology, Hauz Khas, New Delhi, India. Electronic address:

Recombinant protein production by various host organisms is strictly regulated, which is determined mainly by host cell genetics and maintenance of process variables within desirable limits in a reactor. Since the process dynamics typically exhibit nonlinear interactions amongst the critical process variables, the commonly employed controllers are suboptimal for control of most bioprocesses. In this article, we present the implementation of an augmented controller for improving the production of recombinant human serum albumin using Pichia pastoris. Read More

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December 2018

Vernal Keratoconjunctivitis.

Surv Ophthalmol 2018 Dec 11. Epub 2018 Dec 11.

Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Vernal keratoconjunctivitis, a chronic, bilateral, seasonal allergic inflammatory disease of the eye, is an important cause of visual debilitation and impairment of quality of life in children and young adults in certain parts of the world such as the Mediterranean areas, Central and West Africa, the Middle East, Japan, the Indian subcontinent, and South America. It usually has a self-limiting course; however, in a few cases the disease is recurrent and leads to long-term visual disabling complications like keratoconus and limbal stem cell deficiency. The main pathogenic mechanism is IgE mediated; however, there may be non-IgE and certain non-specific hypersensitivity mechanisms. Read More

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December 2018

Molecular diagnostics of disorders of sexual development: an Indian survey and systems biology perspective.

Syst Biol Reprod Med 2018 Dec 14:1-16. Epub 2018 Dec 14.

b Division of Pharmacology and Toxicology , CSIR- Indian Institute of Chemical Technology , Hyderabad , India.

We aimed to survey the monogenic causes of disorders of sex development (DSD) and thereby its prevalence in India. This study revealed mutations resulting in androgen insensitivity syndrome, 5α-reductase type 2 deficiency, and gonadal dysgenesis were commonly reported. Intriguingly, AR deficits were the most prevalent (32 mutations) and of 11/26 missense mutations were in exons 4-8 (encoding ligand binding domain). Read More

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December 2018

Climate change impact and adaptation for wheat protein.

Glob Chang Biol 2019 Jan 22;25(1):155-173. Epub 2018 Nov 22.

Institute of Crop Science and Resource Conservation INRES, University of Bonn, Bonn, Germany.

Wheat grain protein concentration is an important determinant of wheat quality for human nutrition that is often overlooked in efforts to improve crop production. We tested and applied a 32-multi-model ensemble to simulate global wheat yield and quality in a changing climate. Potential benefits of elevated atmospheric CO concentration by 2050 on global wheat grain and protein yield are likely to be negated by impacts from rising temperature and changes in rainfall, but with considerable disparities between regions. Read More

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January 2019
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Plasma metabolite profiling and chemometric analyses of tobacco snuff dippers and patients with oral cancer: Relationship between metabolic signatures.

Head Neck 2018 Dec 13. Epub 2018 Dec 13.

H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.

Background: Cancer of oral cavity is a seriously growing problem in many parts of the world. In Indian subcontinent, most of these cases have been attributed to the use of tobacco-related products. This study is focused on the identification of distinguishing metabolites of oral cancer in comparison with tobacco snuff dippers and healthy controls. Read More

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December 2018

The strength of ecological subsidies across ecosystems: a latitudinal gradient of direct and indirect impacts on food webs.

Ecol Lett 2018 Dec 12. Epub 2018 Dec 12.

Department of Biology, Université de Moncton, Moncton, New Brunswick, E1A 3E9, Canada.

Material and energy flows among ecosystems can directly and indirectly drive ecosystem functions. Yet, how populations of consumers respond to allochthonous inputs at a macroecological scale is still unclear. Using a meta-analysis spanning several biomes, we show that the abundance of recipient populations is 36-57% larger with increased allochthonous inputs. Read More

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December 2018

Defining the complement C3 binding site and the antigenic region of Haemonchus contortus GAPDH.

Parasite Immunol 2018 Dec 12:e12611. Epub 2018 Dec 12.

Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Izatnagar, India, 243122.

Haemonchus contortus is an economically important parasite that survives the host defense system by modulating the immune response. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is secreted by the parasite and the host responds by producing anti-enzyme antibodies. The enzyme inhibits complement cascade, an arm of the innate immunity, by binding to complement C3. Read More

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December 2018

Modulation of Excited-State Proton Transfer Dynamics Inside the Nanocavity of Microheterogeneous Systems: Microenvironment-Sensitive Förster Energy Transfer to Riboflavin.

Chemphyschem 2018 Dec 12. Epub 2018 Dec 12.

Indian Institute of Science, Department of Organic Chemistry, Tala Marg, 560012, Bangalore, INDIA.

Excited-state proton transfer efficiency of a tetraarylpyrene derivative, 1,3,6,8-tetrakis(4-hydroxy-2,6-dimethylphenyl)pyrene (TDMPP) was investigated thoroughly in the presence of various surfactant assemblies, such as micelles, vesicles, etc. The confined microheterogeneous environments can significantly retard the extent of excited-state proton transfer process, resulting in a distinguishable optical signal compared to that in the bulk medium. Physical characteristics of the surfactant assemblies such as order, interfacial hydration and surface charge influence the proton transfer process, and allow multiparametric sensing. Read More

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December 2018

Gold-Catalyzed 1,2-Oxyalkynylation of N-Allenamides with Ethylnylbenziodoxolones.

Org Lett 2018 Dec 14. Epub 2018 Dec 14.

Department of Chemistry , Indian Institute of Science Education and Research Bhopal , Bhauri, Bhopal - 462 066 , India.

A gold-catalyzed 1,2-oxyalkynylation of N-allenamides with ethylnylbenziodoxolones (EBXs) has been achieved for the first time. The reaction, which follows a redox-neutral Au(I)/Au(III) catalytic pathway, was enabled in an attempt to exhaust the EBX reagents atom-economically by putting the nucleophilic carboxylate part of EBXs to appropriate use. This constitutes the first example for gold-catalyzed β-alkynylation of N-allenamides to construct highly valuable 1,3-enynes. Read More

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December 2018

Iodine monobromide catalysed regioselective synthesis of 3-arylquinolines from α-aminoacetophenones and trans-β-nitrostyrenes.

Org Biomol Chem 2018 Dec 14. Epub 2018 Dec 14.

Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, India.

A simple and efficient method for regioselective synthesis of 3-arylquinolines is described from α-aminoacetophenones and trans-β-nitrostyrenes using 20 mol% iodine monobromide as a catalyst in acetonitrile solvent at 80 °C. The present method involves tandem reaction of α-aminoacetophenones and trans-β-nitrostyrenes, formation of two new C-C bonds and cleavage of one C-C bond in a single step. The salient features of the protocol are metal- and oxidant-free reaction conditions, broad substrate scope, and good yields. Read More

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December 2018

Lipid levels, insulin resistance and cardiovascular risk over 96 weeks of antiretroviral therapy: a randomised controlled trial comparing low-dose stavudine and tenofovir.

Retrovirology 2018 Dec 14;15(1):77. Epub 2018 Dec 14.

Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.

Background: HIV infection and antiretroviral treatment are associated with changes in lipid levels, insulin resistance and risk of cardiovascular disease (CVD). We investigated these changes in the first 96 weeks of treatment with low-dose stavudine or tenofovir regimens.

Methods: This is a secondary analysis of a double blind, randomised controlled trial performed in South-Africa, Uganda and India comparing low-dose stavudine (20 mg twice daily) with tenofovir in combination with efavirenz and lamivudine in antiretroviral-naïve adults (n = 1067) (Clinicaltrials. Read More

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December 2018

Tobacco Cessation Among Acute Coronary Syndrome Patients in Kerala, India: Patient and Provider Perspectives.

Qual Health Res 2018 Dec 14:1049732318817047. Epub 2018 Dec 14.

5 Centre for Chronic Disease Control & Public Health Foundation of India, Gurgaon, Haryana, India.

Tobacco cessation is an important intervention to reduce mortality from ischemic heart disease, the leading cause of death in India. In this study, we explored facilitators, barriers, and cultural context to tobacco cessation among acute coronary syndrome (ACS, or heart attack) patients and providers in a tertiary care institution in the south Indian state of Kerala, with a focus on patient trajectories. Patients who quit tobacco after ACS expressed greater understanding about the link between tobacco and ACS, exerted more willpower at the time of discharge, and held less fatalistic beliefs about their health compared to those who continued tobacco use. Read More

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December 2018

Topological Hourglass Dirac Semimetal in the Nonpolar Phase of Ag_{2}BiO_{3}.

Phys Rev Lett 2018 Nov;121(22):226401

Department of Physics, Northeastern University, Boston, Massachusetts 02115, USA.

Materials with tunable charge and lattice degrees of freedom provide excellent platforms for investigating multiple phases that can be controlled via external stimuli. We show how the charge-ordered ferroelectric oxide Ag_{2}BiO_{3}, which has been realized experimentally, presents a unique exemplar of a metal-insulator transition under an external electric field. Our first-principles calculations, combined with a symmetry analysis, reveal the presence of a nearly ideal hourglass-Dirac-semimetal state in the nonpolar structure of Ag_{2}BiO_{3}. Read More

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November 2018

Evidence for the Associated Production of a Single Top Quark and a Photon in Proton-Proton Collisions at sqrt[s]=13  TeV.

Authors:
A M Sirunyan A Tumasyan W Adam F Ambrogi E Asilar T Bergauer J Brandstetter M Dragicevic J Erö A Escalante Del Valle M Flechl R Frühwirth V M Ghete J Hrubec M Jeitler N Krammer I Krätschmer D Liko T Madlener I Mikulec N Rad H Rohringer J Schieck R Schöfbeck M Spanring D Spitzbart A Taurok W Waltenberger J Wittmann C-E Wulz M Zarucki V Chekhovsky V Mossolov J Suarez Gonzalez E A De Wolf D Di Croce X Janssen J Lauwers M Pieters H Van Haevermaet P Van Mechelen N Van Remortel S Abu Zeid F Blekman J D'Hondt I De Bruyn J De Clercq K Deroover G Flouris D Lontkovskyi S Lowette I Marchesini S Moortgat L Moreels Q Python K Skovpen S Tavernier W Van Doninck P Van Mulders I Van Parijs D Beghin B Bilin H Brun B Clerbaux G De Lentdecker H Delannoy B Dorney G Fasanella L Favart R Goldouzian A Grebenyuk A K Kalsi T Lenzi J Luetic N Postiau E Starling L Thomas C Vander Velde P Vanlaer D Vannerom Q Wang T Cornelis D Dobur A Fagot M Gul I Khvastunov D Poyraz C Roskas D Trocino M Tytgat W Verbeke B Vermassen M Vit N Zaganidis H Bakhshiansohi O Bondu S Brochet G Bruno C Caputo P David C Delaere M Delcourt B Francois A Giammanco G Krintiras V Lemaitre A Magitteri A Mertens M Musich K Piotrzkowski A Saggio M Vidal Marono S Wertz J Zobec F L Alves G A Alves M Correa Martins Junior G Correia Silva C Hensel A Moraes M E Pol P Rebello Teles E Belchior Batista Das Chagas W Carvalho J Chinellato E Coelho E M Da Costa G G Da Silveira D De Jesus Damiao C De Oliveira Martins S Fonseca De Souza H Malbouisson D Matos Figueiredo M Melo De Almeida C Mora Herrera L Mundim H Nogima W L Prado Da Silva L J Sanchez Rosas A Santoro A Sznajder M Thiel E J Tonelli Manganote F Torres Da Silva De Araujo A Vilela Pereira S Ahuja C A Bernardes L Calligaris T R Fernandez Perez Tomei E M Gregores P G Mercadante S F Novaes Sandra S Padula A Aleksandrov R Hadjiiska P Iaydjiev A Marinov M Misheva M Rodozov M Shopova G Sultanov A Dimitrov L Litov B Pavlov P Petkov W Fang X Gao L Yuan M Ahmad J G Bian G M Chen H S Chen M Chen Y Chen C H Jiang D Leggat H Liao Z Liu F Romeo S M Shaheen A Spiezia J Tao Z Wang E Yazgan H Zhang S Zhang J Zhao Y Ban G Chen A Levin J Li L Li Q Li Y Mao S J Qian D Wang Z Xu Y Wang C Avila A Cabrera C A Carrillo Montoya L F Chaparro Sierra C Florez C F González Hernández M A Segura Delgado B Courbon N Godinovic D Lelas I Puljak T Sculac Z Antunovic M Kovac V Brigljevic D Ferencek K Kadija B Mesic A Starodumov T Susa M W Ather A Attikis M Kolosova G Mavromanolakis J Mousa C Nicolaou F Ptochos P A Razis H Rykaczewski M Finger M Finger E Ayala E Carrera Jarrin H Abdalla A A Abdelalim E Salama S Bhowmik A Carvalho Antunes De Oliveira R K Dewanjee K Ehataht M Kadastik M Raidal C Veelken P Eerola H Kirschenmann J Pekkanen M Voutilainen J Havukainen J K Heikkilä T Järvinen V Karimäki R Kinnunen T Lampén K Lassila-Perini S Laurila S Lehti T Lindén P Luukka T Mäenpää H Siikonen E Tuominen J Tuominiemi T Tuuva M Besancon F Couderc M Dejardin D Denegri J L Faure F Ferri S Ganjour A Givernaud P Gras G Hamel de Monchenault P Jarry C Leloup E Locci J Malcles G Negro J Rander A Rosowsky M Ö Sahin M Titov A Abdulsalam C Amendola I Antropov F Beaudette P Busson C Charlot R Granier de Cassagnac I Kucher A Lobanov J Martin Blanco C Martin Perez M Nguyen C Ochando G Ortona P Paganini P Pigard J Rembser R Salerno J B Sauvan Y Sirois A G Stahl Leiton A Zabi A Zghiche J-L Agram J Andrea D Bloch J-M Brom E C Chabert V Cherepanov C Collard E Conte J-C Fontaine D Gelé U Goerlach M Jansová A-C Le Bihan N Tonon P Van Hove S Gadrat S Beauceron C Bernet G Boudoul N Chanon R Chierici D Contardo P Depasse H El Mamouni J Fay L Finco S Gascon M Gouzevitch G Grenier B Ille F Lagarde I B Laktineh H Lattaud M Lethuillier L Mirabito S Perries A Popov V Sordini G Touquet M Vander Donckt S Viret A Khvedelidze Z Tsamalaidze C Autermann L Feld M K Kiesel K Klein M Lipinski M Preuten M P Rauch C Schomakers J Schulz M Teroerde B Wittmer V Zhukov A Albert D Duchardt M Endres M Erdmann S Erdweg T Esch R Fischer S Ghosh A Güth T Hebbeker C Heidemann K Hoepfner H Keller L Mastrolorenzo M Merschmeyer A Meyer P Millet S Mukherjee T Pook M Radziej H Reithler M Rieger A Schmidt D Teyssier S Thüer G Flügge O Hlushchenko T Kress A Künsken T Müller A Nehrkorn A Nowack C Pistone O Pooth D Roy H Sert A Stahl M Aldaya Martin T Arndt C Asawatangtrakuldee I Babounikau K Beernaert O Behnke U Behrens A Bermúdez Martínez D Bertsche A A Bin Anuar K Borras V Botta A Campbell P Connor C Contreras-Campana V Danilov A De Wit M M Defranchis C Diez Pardos D Domínguez Damiani G Eckerlin T Eichhorn A Elwood E Eren E Gallo A Geiser A Grohsjean M Guthoff M Haranko A Harb J Hauk H Jung M Kasemann J Keaveney C Kleinwort J Knolle D Krücker W Lange A Lelek T Lenz J Leonard K Lipka W Lohmann R Mankel I-A Melzer-Pellmann A B Meyer M Meyer M Missiroli G Mittag J Mnich V Myronenko S K Pflitsch D Pitzl A Raspereza M Savitskyi P Saxena P Schütze C Schwanenberger R Shevchenko A Singh H Tholen O Turkot A Vagnerini G P Van Onsem R Walsh Y Wen K Wichmann C Wissing O Zenaiev R Aggleton S Bein L Benato A Benecke V Blobel T Dreyer E Garutti D Gonzalez P Gunnellini J Haller A Hinzmann A Karavdina G Kasieczka R Klanner R Kogler N Kovalchuk S Kurz V Kutzner J Lange D Marconi J Multhaup M Niedziela C E N Niemeyer D Nowatschin A Perieanu A Reimers O Rieger C Scharf P Schleper S Schumann J Schwandt J Sonneveld H Stadie G Steinbrück F M Stober M Stöver A Vanhoefer B Vormwald I Zoi M Akbiyik C Barth M Baselga S Baur E Butz R Caspart T Chwalek F Colombo W De Boer A Dierlamm K El Morabit N Faltermann B Freund M Giffels M A Harrendorf F Hartmann S M Heindl U Husemann F Kassel I Katkov S Kudella H Mildner S Mitra M U Mozer Th Müller M Plagge G Quast K Rabbertz M Schröder I Shvetsov G Sieber H J Simonis R Ulrich S Wayand M Weber T Weiler S Williamson C Wöhrmann R Wolf G Anagnostou G Daskalakis T Geralis A Kyriakis D Loukas G Paspalaki I Topsis-Giotis G Karathanasis S Kesisoglou P Kontaxakis A Panagiotou I Papavergou N Saoulidou E Tziaferi K Vellidis K Kousouris I Papakrivopoulos G Tsipolitis I Evangelou C Foudas P Gianneios P Katsoulis P Kokkas S Mallios N Manthos I Papadopoulos E Paradas J Strologas F A Triantis D Tsitsonis M Bartók M Csanad N Filipovic P Major M I Nagy G Pasztor O Surányi G I Veres G Bencze C Hajdu D Horvath Á Hunyadi F Sikler T Á Vámi V Veszpremi G Vesztergombi N Beni S Czellar J Karancsi A Makovec J Molnar Z Szillasi P Raics Z L Trocsanyi B Ujvari S Choudhury J R Komaragiri P C Tiwari S Bahinipati C Kar P Mal K Mandal A Nayak D K Sahoo S K Swain S Bansal S B Beri V Bhatnagar S Chauhan R Chawla N Dhingra R Gupta A Kaur M Kaur S Kaur R Kumar P Kumari M Lohan A Mehta K Sandeep S Sharma J B Singh A K Virdi G Walia A Bhardwaj B C Choudhary R B Garg M Gola S Keshri Ashok Kumar S Malhotra M Naimuddin P Priyanka K Ranjan Aashaq Shah R Sharma R Bhardwaj M Bharti R Bhattacharya S Bhattacharya U Bhawandeep D Bhowmik S Dey S Dutt S Dutta S Ghosh K Mondal S Nandan A Purohit P K Rout A Roy S Roy Chowdhury G Saha S Sarkar M Sharan B Singh S Thakur P K Behera R Chudasama D Dutta V Jha V Kumar P K Netrakanti L M Pant P Shukla T Aziz M A Bhat S Dugad G B Mohanty N Sur B Sutar Ravindra Kumar Verma S Banerjee S Bhattacharya S Chatterjee P Das M Guchait Sa Jain S Karmakar S Kumar M Maity G Majumder K Mazumdar N Sahoo T Sarkar S Chauhan S Dube V Hegde A Kapoor K Kothekar S Pandey A Rane S Sharma S Chenarani E Eskandari Tadavani S M Etesami M Khakzad M Mohammadi Najafabadi M Naseri F Rezaei Hosseinabadi B Safarzadeh M Zeinali M Felcini M Grunewald M Abbrescia C Calabria A Colaleo D Creanza L Cristella N De Filippis M De Palma A Di Florio F Errico L Fiore A Gelmi G Iaselli M Ince S Lezki G Maggi M Maggi G Miniello S My S Nuzzo A Pompili G Pugliese R Radogna A Ranieri G Selvaggi A Sharma L Silvestris R Venditti P Verwilligen G Zito G Abbiendi C Battilana D Bonacorsi L Borgonovi S Braibant-Giacomelli R Campanini P Capiluppi A Castro F R Cavallo S S Chhibra C Ciocca G Codispoti M Cuffiani G M Dallavalle F Fabbri A Fanfani E Fontanesi P Giacomelli C Grandi L Guiducci F Iemmi S Lo Meo S Marcellini G Masetti A Montanari F L Navarria A Perrotta F Primavera T Rovelli G P Siroli N Tosi S Albergo A Di Mattia R Potenza A Tricomi C Tuve G Barbagli K Chatterjee V Ciulli C Civinini R D'Alessandro E Focardi G Latino P Lenzi M Meschini S Paoletti L Russo G Sguazzoni D Strom L Viliani L Benussi S Bianco F Fabbri D Piccolo F Ferro F Ravera E Robutti S Tosi A Benaglia A Beschi L Brianza F Brivio V Ciriolo S Di Guida M E Dinardo S Fiorendi S Gennai A Ghezzi P Govoni M Malberti S Malvezzi A Massironi D Menasce F Monti L Moroni M Paganoni D Pedrini S Ragazzi T Tabarelli de Fatis D Zuolo S Buontempo N Cavallo A Di Crescenzo F Fabozzi F Fienga G Galati A O M Iorio W A Khan L Lista S Meola P Paolucci C Sciacca E Voevodina P Azzi N Bacchetta D Bisello A Boletti A Bragagnolo R Carlin P Checchia M Dall'Osso P De Castro Manzano T Dorigo U Dosselli F Gasparini U Gasparini A Gozzelino S Y Hoh S Lacaprara P Lujan M Margoni A T Meneguzzo J Pazzini P Ronchese R Rossin F Simonetto A Tiko E Torassa M Zanetti P Zotto G Zumerle A Braghieri A Magnani P Montagna S P Ratti V Re M Ressegotti C Riccardi P Salvini I Vai P Vitulo M Biasini G M Bilei C Cecchi D Ciangottini L Fanò P Lariccia R Leonardi E Manoni G Mantovani V Mariani M Menichelli A Rossi A Santocchia D Spiga K Androsov P Azzurri G Bagliesi L Bianchini T Boccali L Borrello R Castaldi M A Ciocci R Dell'Orso G Fedi F Fiori L Giannini A Giassi M T Grippo F Ligabue E Manca G Mandorli A Messineo F Palla A Rizzi P Spagnolo R Tenchini G Tonelli A Venturi P G Verdini L Barone F Cavallari M Cipriani D Del Re E Di Marco M Diemoz S Gelli E Longo B Marzocchi P Meridiani G Organtini F Pandolfi R Paramatti F Preiato S Rahatlou C Rovelli F Santanastasio N Amapane R Arcidiacono S Argiro M Arneodo N Bartosik R Bellan C Biino N Cartiglia F Cenna S Cometti M Costa R Covarelli N Demaria B Kiani C Mariotti S Maselli E Migliore V Monaco E Monteil M Monteno M M Obertino L Pacher N Pastrone M Pelliccioni G L Pinna Angioni A Romero M Ruspa R Sacchi K Shchelina V Sola A Solano D Soldi A Staiano S Belforte V Candelise M Casarsa F Cossutti A Da Rold G Della Ricca F Vazzoler A Zanetti D H Kim G N Kim M S Kim J Lee S Lee S W Lee C S Moon Y D Oh S I Pak S Sekmen D C Son Y C Yang H Kim D H Moon G Oh J Goh T J Kim S Cho S Choi Y Go D Gyun S Ha B Hong Y Jo K Lee K S Lee S Lee J Lim S K Park Y Roh H S Kim J Almond J Kim J S Kim H Lee K Lee K Nam S B Oh B C Radburn-Smith S H Seo U K Yang H D Yoo G B Yu D Jeon H Kim J H Kim J S H Lee I C Park Y Choi C Hwang J Lee I Yu V Dudenas A Juodagalvis J Vaitkus I Ahmed Z A Ibrahim M A B Md Ali F Mohamad Idris W A T Wan Abdullah M N Yusli Z Zolkapli J F Benitez A Castaneda Hernandez J A Murillo Quijada H Castilla-Valdez E De La Cruz-Burelo M C Duran-Osuna I Heredia-De La Cruz R Lopez-Fernandez J Mejia Guisao R I Rabadan-Trejo M Ramirez-Garcia G Ramirez-Sanchez R Reyes-Almanza A Sanchez-Hernandez S Carrillo Moreno C Oropeza Barrera F Vazquez Valencia J Eysermans I Pedraza H A Salazar Ibarguen C Uribe Estrada A Morelos Pineda D Krofcheck S Bheesette P H Butler A Ahmad M Ahmad M I Asghar Q Hassan H R Hoorani A Saddique M A Shah M Shoaib M Waqas H Bialkowska M Bluj B Boimska T Frueboes M Górski M Kazana M Szleper P Traczyk P Zalewski K Bunkowski A Byszuk K Doroba A Kalinowski M Konecki J Krolikowski M Misiura M Olszewski A Pyskir M Walczak M Araujo P Bargassa C Beirão Da Cruz E Silva A Di Francesco P Faccioli B Galinhas M Gallinaro J Hollar N Leonardo M V Nemallapudi J Seixas G Strong O Toldaiev D Vadruccio J Varela S Afanasiev P Bunin M Gavrilenko I Golutvin I Gorbunov A Kamenev V Karjavine A Lanev A Malakhov V Matveev P Moisenz V Palichik V Perelygin S Shmatov S Shulha N Skatchkov V Smirnov N Voytishin A Zarubin V Golovtsov Y Ivanov V Kim E Kuznetsova P Levchenko V Murzin V Oreshkin I Smirnov D Sosnov V Sulimov L Uvarov S Vavilov A Vorobyev Yu Andreev A Dermenev S Gninenko N Golubev A Karneyeu M Kirsanov N Krasnikov A Pashenkov D Tlisov A Toropin V Epshteyn V Gavrilov N Lychkovskaya V Popov I Pozdnyakov G Safronov A Spiridonov A Stepennov V Stolin M Toms E Vlasov A Zhokin T Aushev R Chistov M Danilov P Parygin D Philippov S Polikarpov E Tarkovskii V Andreev M Azarkin I Dremin M Kirakosyan S V Rusakov A Terkulov A Baskakov A Belyaev E Boos V Bunichev M Dubinin L Dudko V Klyukhin O Kodolova N Korneeva I Lokhtin I Miagkov S Obraztsov M Perfilov V Savrin P Volkov A Barnyakov V Blinov T Dimova L Kardapoltsev Y Skovpen I Azhgirey I Bayshev S Bitioukov D Elumakhov A Godizov V Kachanov A Kalinin D Konstantinov P Mandrik V Petrov R Ryutin S Slabospitskii A Sobol S Troshin N Tyurin A Uzunian A Volkov A Babaev S Baidali V Okhotnikov P Adzic P Cirkovic D Devetak M Dordevic J Milosevic J Alcaraz Maestre A Álvarez Fernández I Bachiller M Barrio Luna J A Brochero Cifuentes M Cerrada N Colino B De La Cruz A Delgado Peris C Fernandez Bedoya J P Fernández Ramos J Flix M C Fouz O Gonzalez Lopez S Goy Lopez J M Hernandez M I Josa D Moran A Pérez-Calero Yzquierdo J Puerta Pelayo I Redondo L Romero M S Soares A Triossi C Albajar J F de Trocóniz J Cuevas C Erice J Fernandez Menendez S Folgueras I Gonzalez Caballero J R González Fernández E Palencia Cortezon V Rodríguez Bouza S Sanchez Cruz P Vischia J M Vizan Garcia I J Cabrillo A Calderon B Chazin Quero J Duarte Campderros M Fernandez P J Fernández Manteca A García Alonso J Garcia-Ferrero G Gomez A Lopez Virto J Marco C Martinez Rivero P Martinez Ruiz Del Arbol F Matorras J Piedra Gomez C Prieels T Rodrigo A Ruiz-Jimeno L Scodellaro N Trevisani I Vila R Vilar Cortabitarte N Wickramage D Abbaneo B Akgun E Auffray G Auzinger P Baillon A H Ball D Barney J Bendavid M Bianco A Bocci C Botta E Brondolin T Camporesi M Cepeda G Cerminara E Chapon Y Chen G Cucciati D d'Enterria A Dabrowski N Daci V Daponte A David A De Roeck N Deelen M Dobson M Dünser N Dupont A Elliott-Peisert P Everaerts F Fallavollita D Fasanella G Franzoni J Fulcher W Funk D Gigi A Gilbert K Gill F Glege M Guilbaud D Gulhan J Hegeman C Heidegger V Innocente A Jafari P Janot O Karacheban J Kieseler A Kornmayer M Krammer C Lange P Lecoq C Lourenço L Malgeri M Mannelli F Meijers J A Merlin S Mersi E Meschi P Milenovic F Moortgat M Mulders J Ngadiuba S Nourbakhsh S Orfanelli L Orsini F Pantaleo L Pape E Perez M Peruzzi A Petrilli G Petrucciani A Pfeiffer M Pierini F M Pitters D Rabady A Racz T Reis G Rolandi M Rovere H Sakulin C Schäfer C Schwick M Seidel M Selvaggi A Sharma P Silva P Sphicas A Stakia J Steggemann M Tosi D Treille A Tsirou V Veckalns M Verzetti W D Zeuner L Caminada K Deiters W Erdmann R Horisberger Q Ingram H C Kaestli D Kotlinski U Langenegger T Rohe S A Wiederkehr M Backhaus L Bäni P Berger N Chernyavskaya G Dissertori M Dittmar M Donegà C Dorfer T A Gómez Espinosa C Grab D Hits T Klijnsma W Lustermann R A Manzoni M Marionneau M T Meinhard F Micheli P Musella F Nessi-Tedaldi J Pata F Pauss G Perrin L Perrozzi S Pigazzini M Quittnat C Reissel D Ruini D A Sanz Becerra M Schönenberger L Shchutska V R Tavolaro K Theofilatos M L Vesterbacka Olsson R Wallny D H Zhu T K Aarrestad C Amsler D Brzhechko M F Canelli A De Cosa R Del Burgo S Donato C Galloni T Hreus B Kilminster S Leontsinis I Neutelings D Pinna G Rauco P Robmann D Salerno K Schweiger C Seitz Y Takahashi A Zucchetta Y H Chang K Y Cheng T H Doan R Khurana C M Kuo W Lin A Pozdnyakov S S Yu P Chang Y Chao K F Chen P H Chen W-S Hou Arun Kumar Y F Liu R-S Lu E Paganis A Psallidas A Steen B Asavapibhop N Srimanobhas N Suwonjandee A Bat F Boran S Cerci S Damarseckin Z S Demiroglu F Dolek C Dozen I Dumanoglu S Girgis G Gokbulut Y Guler E Gurpinar I Hos C Isik E E Kangal O Kara A Kayis Topaksu U Kiminsu M Oglakci G Onengut K Ozdemir S Ozturk D Sunar Cerci B Tali U G Tok S Turkcapar I S Zorbakir C Zorbilmez B Isildak G Karapinar M Yalvac M Zeyrek I O Atakisi E Gülmez M Kaya O Kaya S Ozkorucuklu S Tekten E A Yetkin M N Agaras A Cakir K Cankocak Y Komurcu S Sen B Grynyov L Levchuk F Ball L Beck J J Brooke D Burns E Clement D Cussans O Davignon H Flacher J Goldstein G P Heath H F Heath L Kreczko D M Newbold S Paramesvaran B Penning T Sakuma D Smith V J Smith J Taylor A Titterton K W Bell A Belyaev C Brew R M Brown D Cieri D J A Cockerill J A Coughlan K Harder S Harper J Linacre E Olaiya D Petyt C H Shepherd-Themistocleous A Thea I R Tomalin T Williams W J Womersley R Bainbridge P Bloch J Borg S Breeze O Buchmuller A Bundock D Colling P Dauncey G Davies M Della Negra R Di Maria Y Haddad G Hall G Iles T James M Komm C Laner L Lyons A-M Magnan S Malik A Martelli J Nash A Nikitenko V Palladino M Pesaresi D M Raymond A Richards A Rose E Scott C Seez A Shtipliyski G Singh M Stoye T Strebler S Summers A Tapper K Uchida T Virdee N Wardle D Winterbottom J Wright S C Zenz J E Cole P R Hobson A Khan P Kyberd C K Mackay A Morton I D Reid L Teodorescu S Zahid K Call J Dittmann K Hatakeyama H Liu C Madrid B Mcmaster N Pastika C Smith R Bartek A Dominguez A Buccilli S I Cooper C Henderson P Rumerio C West D Arcaro T Bose D Gastler D Rankin C Richardson J Rohlf L Sulak D Zou G Benelli X Coubez D Cutts M Hadley J Hakala U Heintz J M Hogan K H M Kwok E Laird G Landsberg J Lee Z Mao M Narain S Sagir R Syarif E Usai D Yu R Band C Brainerd R Breedon D Burns M Calderon De La Barca Sanchez M Chertok J Conway R Conway P T Cox R Erbacher C Flores G Funk W Ko O Kukral R Lander M Mulhearn D Pellett J Pilot S Shalhout M Shi D Stolp D Taylor K Tos M Tripathi Z Wang F Zhang M Bachtis C Bravo R Cousins A Dasgupta A Florent J Hauser M Ignatenko N Mccoll S Regnard D Saltzberg C Schnaible V Valuev E Bouvier K Burt R Clare J W Gary S M A Ghiasi Shirazi G Hanson G Karapostoli E Kennedy F Lacroix O R Long M Olmedo Negrete M I Paneva W Si L Wang H Wei S Wimpenny B R Yates J G Branson P Chang S Cittolin M Derdzinski R Gerosa D Gilbert B Hashemi A Holzner D Klein G Kole V Krutelyov J Letts M Masciovecchio D Olivito S Padhi M Pieri M Sani V Sharma S Simon M Tadel A Vartak S Wasserbaech J Wood F Würthwein A Yagil G Zevi Della Porta N Amin R Bhandari J Bradmiller-Feld C Campagnari M Citron A Dishaw V Dutta M Franco Sevilla L Gouskos R Heller J Incandela A Ovcharova H Qu J Richman D Stuart I Suarez S Wang J Yoo D Anderson A Bornheim J M Lawhorn H B Newman T Q Nguyen M Spiropulu J R Vlimant R Wilkinson S Xie Z Zhang R Y Zhu M B Andrews T Ferguson T Mudholkar M Paulini M Sun I Vorobiev M Weinberg J P Cumalat W T Ford F Jensen A Johnson M Krohn E MacDonald T Mulholland R Patel K Stenson K A Ulmer S R Wagner J Alexander J Chaves Y Cheng J Chu A Datta K Mcdermott N Mirman J R Patterson D Quach A Rinkevicius A Ryd L Skinnari L Soffi S M Tan Z Tao J Thom J Tucker P Wittich M Zientek S Abdullin M Albrow M Alyari G Apollinari A Apresyan A Apyan S Banerjee L A T Bauerdick A Beretvas J Berryhill P C Bhat G Bolla K Burkett J N Butler A Canepa G B Cerati H W K Cheung F Chlebana M Cremonesi J Duarte V D Elvira J Freeman Z Gecse E Gottschalk L Gray D Green S Grünendahl O Gutsche J Hanlon R M Harris S Hasegawa J Hirschauer Z Hu B Jayatilaka S Jindariani M Johnson U Joshi B Klima M J Kortelainen B Kreis S Lammel D Lincoln R Lipton M Liu T Liu J Lykken K Maeshima J M Marraffino D Mason P McBride P Merkel S Mrenna S Nahn V O'Dell K Pedro C Pena O Prokofyev G Rakness L Ristori A Savoy-Navarro B Schneider E Sexton-Kennedy A Soha W J Spalding L Spiegel S Stoynev J Strait N Strobbe L Taylor S Tkaczyk N V Tran L Uplegger E W Vaandering C Vernieri M Verzocchi R Vidal M Wang H A Weber A Whitbeck D Acosta P Avery P Bortignon D Bourilkov A Brinkerhoff L Cadamuro A Carnes M Carver D Curry R D Field S V Gleyzer B M Joshi J Konigsberg A Korytov K H Lo P Ma K Matchev H Mei G Mitselmakher D Rosenzweig K Shi D Sperka J Wang S Wang X Zuo Y R Joshi S Linn A Ackert T Adams A Askew S Hagopian V Hagopian K F Johnson T Kolberg G Martinez T Perry H Prosper A Saha C Schiber R Yohay M M Baarmand V Bhopatkar S Colafranceschi M Hohlmann D Noonan M Rahmani T Roy F Yumiceva M R Adams L Apanasevich D Berry R R Betts R Cavanaugh X Chen S Dittmer O Evdokimov C E Gerber D A Hangal D J Hofman K Jung J Kamin C Mills I D Sandoval Gonzalez M B Tonjes H Trauger N Varelas H Wang X Wang Z Wu J Zhang M Alhusseini B Bilki W Clarida K Dilsiz S Durgut R P Gandrajula M Haytmyradov V Khristenko J-P Merlo A Mestvirishvili A Moeller J Nachtman H Ogul Y Onel F Ozok A Penzo C Snyder E Tiras J Wetzel B Blumenfeld A Cocoros N Eminizer D Fehling L Feng A V Gritsan W T Hung P Maksimovic J Roskes U Sarica M Swartz M Xiao C You A Al-Bataineh P Baringer A Bean S Boren J Bowen A Bylinkin J Castle S Khalil A Kropivnitskaya D Majumder W Mcbrayer M Murray C Rogan S Sanders E Schmitz J D Tapia Takaki Q Wang S Duric A Ivanov K Kaadze D Kim Y Maravin D R Mendis T Mitchell A Modak A Mohammadi L K Saini N Skhirtladze F Rebassoo D Wright A Baden O Baron A Belloni S C Eno Y Feng C Ferraioli N J Hadley S Jabeen G Y Jeng R G Kellogg J Kunkle A C Mignerey S Nabili F Ricci-Tam Y H Shin A Skuja S C Tonwar K Wong D Abercrombie B Allen V Azzolini A Baty G Bauer R Bi S Brandt W Busza I A Cali M D'Alfonso Z Demiragli G Gomez Ceballos M Goncharov P Harris D Hsu M Hu Y Iiyama G M Innocenti M Klute D Kovalskyi Y-J Lee P D Luckey B Maier A C Marini C Mcginn C Mironov S Narayanan X Niu C Paus C Roland G Roland G S F Stephans K Sumorok K Tatar D Velicanu J Wang T W Wang B Wyslouch S Zhaozhong A C Benvenuti R M Chatterjee A Evans P Hansen Sh Jain S Kalafut Y Kubota Z Lesko J Mans N Ruckstuhl R Rusack J Turkewitz M A Wadud J G Acosta S Oliveros E Avdeeva K Bloom D R Claes C Fangmeier F Golf R Gonzalez Suarez R Kamalieddin I Kravchenko J Monroy J E Siado G R Snow B Stieger A Godshalk C Harrington I Iashvili A Kharchilava C Mclean D Nguyen A Parker S Rappoccio B Roozbahani G Alverson E Barberis C Freer A Hortiangtham D M Morse T Orimoto R Teixeira De Lima T Wamorkar B Wang A Wisecarver D Wood S Bhattacharya O Charaf K A Hahn N Mucia N Odell M H Schmitt K Sung M Trovato M Velasco R Bucci N Dev M Hildreth K Hurtado Anampa C Jessop D J Karmgard N Kellams K Lannon W Li N Loukas N Marinelli F Meng C Mueller Y Musienko M Planer A Reinsvold R Ruchti P Siddireddy G Smith S Taroni M Wayne A Wightman M Wolf A Woodard J Alimena L Antonelli B Bylsma L S Durkin S Flowers B Francis A Hart C Hill W Ji T Y Ling W Luo B L Winer S Cooperstein P Elmer J Hardenbrook S Higginbotham A Kalogeropoulos D Lange M T Lucchini J Luo D Marlow K Mei I Ojalvo J Olsen C Palmer P Piroué J Salfeld-Nebgen D Stickland C Tully S Malik S Norberg A Barker V E Barnes S Das L Gutay M Jones A W Jung A Khatiwada B Mahakud D H Miller N Neumeister C C Peng S Piperov H Qiu J F Schulte J Sun F Wang R Xiao W Xie T Cheng J Dolen N Parashar Z Chen K M Ecklund S Freed F J M Geurts M Kilpatrick W Li B P Padley R Redjimi J Roberts J Rorie W Shi Z Tu J Zabel A Zhang A Bodek P de Barbaro R Demina Y T Duh J L Dulemba C Fallon T Ferbel M Galanti A Garcia-Bellido J Han O Hindrichs A Khukhunaishvili P Tan R Taus A Agapitos J P Chou Y Gershtein E Halkiadakis M Heindl E Hughes S Kaplan R Kunnawalkam Elayavalli S Kyriacou A Lath R Montalvo K Nash M Osherson H Saka S Salur S Schnetzer D Sheffield S Somalwar R Stone S Thomas P Thomassen M Walker A G Delannoy J Heideman G Riley S Spanier O Bouhali A Celik M Dalchenko M De Mattia A Delgado S Dildick R Eusebi J Gilmore T Huang T Kamon S Luo R Mueller A Perloff L Perniè D Rathjens A Safonov N Akchurin J Damgov F De Guio P R Dudero S Kunori K Lamichhane S W Lee T Mengke S Muthumuni T Peltola S Undleeb I Volobouev Z Wang S Greene A Gurrola R Janjam W Johns C Maguire A Melo H Ni K Padeken J D Ruiz Alvarez P Sheldon S Tuo J Velkovska M Verweij Q Xu M W Arenton P Barria B Cox R Hirosky M Joyce A Ledovskoy H Li C Neu T Sinthuprasith Y Wang E Wolfe F Xia R Harr P E Karchin N Poudyal J Sturdy P Thapa S Zaleski M Brodski J Buchanan C Caillol D Carlsmith S Dasu L Dodd B Gomber M Grothe M Herndon A Hervé U Hussain P Klabbers A Lanaro K Long R Loveless T Ruggles A Savin V Sharma N Smith W H Smith N Woods

Phys Rev Lett 2018 Nov;121(22):221802

University of Wisconsin, Madison, Wisconsin, USA.

The first evidence of events consistent with the production of a single top quark in association with a photon is reported. The analysis is based on proton-proton collisions at sqrt[s]=13  TeV and recorded by the CMS experiment in 2016, corresponding to an integrated luminosity of 35.9  fb^{-1}. Read More

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November 2018

Anomalous origin of pulmonary branches from the ascending aorta. A report of five cases and review of the literature.

J Cardiol Cases 2015 Jan 29;11(1):1-6. Epub 2014 Oct 29.

Pediatric Cardiology Surgery Department, Instituto Nacional de Cardiología "Ignacio Chávez," Mexico City, Mexico.

The anomalous origin of pulmonary branches is a rare entity where, either the right or the left pulmonary arteries arise from the ascending aorta and where the aortic and pulmonary valves are separated. Clinical manifestations usually appear in the infant or, more rarely, in the newborn and include respiratory distress or congestive heart failure due to increased pulmonary resistance.The survival rate in an Indian series was 94% with the death of one patient from Fallot tetralogy. Read More

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January 2015

Dracunculiasis in South Indian bonnet monkey.

Primates 2000 Jan;41(1):89-92

Department of Anatomy, Dr. Arcot Lakshmanasamy Mudaliar Postgraduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, 600 113, Chennai, India.

Dracunculiasis, popularly known as Guinea worm disease, has been eradicated from Tamil Nadu, India, and there have been no indigenous cases reported since 1981. This report describes a female bonnet monkey with dracunculiasis. She presented with fever and a blister in left hind limb. Read More

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January 2000

The Emerging Environmental and Public Health Problem of Electronic Waste in India.

J Health Pollut 2017 Sep 7;7(15):1-7. Epub 2017 Sep 7.

Department of Chemistry, Manav Rachna University, Sector 43, Faridabad, India.

Background: Monumental progress has been made in the area of information and communication technology, leading to a tremendous increase in use of electronic equipment, especially computers and mobile phones. The expansion of production and consumption of electronic equipment along with its shorter life span has led to the generation of tremendous amounts of electronic waste (e-waste). In addition, there is a high level of trans-boundary movement of these devices as second-hand electronic equipment from developed countries, in the name of bridging the digital gap. Read More

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September 2017

Gender Disparity in Lung Function Abnormalities among a Population Exposed to Particulate Matter Concentration in Ambient Air in the National Capital Region, India.

J Health Pollut 2015 Dec 21;5(9):47-60. Epub 2015 Dec 21.

Department of Community Medicine, Hind Institute of Medical Sciences, Lucknow, India.

Background: The World Health Organization (WHO) global air quality study shows that 27 Indian cities, including New Delhi, are among the one hundred cities with the worst air quality globally. The scope of airway obstruction cases among residents in locations with critical air pollution levels like particulate matter (PM) pollutants PM and PM has not been addressed in the National Capital region, India.

Objectives: The present cross-sectional study was undertaken to assess the forced expiratory volume in one second (FEV) % predicted abnormalities among residents living in the National Capital Region, India with respect to their exposure to particulate matter pollutants (PM, PM) in ambient air. Read More

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December 2015

Repurposing Drugs Based on Evolutionary Relationships Between Targets of Approved Drugs and Proteins of Interest.

Methods Mol Biol 2019 ;1903:45-59

Molecular Biophysics Unit, Indian Institute of Science, Bangalore, Karnataka, India.

Drug repurposing has garnered much interest as an effective method for drug development among biopharmaceutical companies. The availability of information on complete sequences of genomes and their associated biological data, genotype-phenotype-disease relationships, and properties of small molecules offers opportunities to explore the repurpose-able potential of existing pharmacopoeia. This method gains further importance, especially, in the context of development of drugs against infectious diseases, some of which pose serious complications due to emergence of drug-resistant pathogens. Read More

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January 2019

Pediatric Thrombotic Events: Incidence, Clinical Risk Factors and Outcome.

Indian J Pediatr 2018 Dec 13. Epub 2018 Dec 13.

Department of Neonatology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India.

Objective: To study the incidence, clinical risk factors and outcome of thrombotic events in pediatric age group of 1 mo-12 y.

Methods: This prospective observational study was conducted in a tertiary care institute from September 2015 through October 2017. Forty nine children with thrombosis from 1 mo-12 y were enrolled. Read More

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December 2018
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Hypoglycemic Profile of Exclusively Breastfed Low Birth Weight Neonates.

Indian J Pediatr 2018 Dec 13. Epub 2018 Dec 13.

Department of Pediatrics, Tata Motors Hospital, Jamshedpur, Jharkhand, India.

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December 2018
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Performance on Paladai Feeding of Preterm Infants with Bronchopulmonary Dysplasia.

Indian J Pediatr 2018 Dec 13. Epub 2018 Dec 13.

Division of Neonatology, Department of Pediatrics, Newborn Health Knowledge Centre, All India Institute of Medical Sciences, New Delhi, 110029, India.

Objective: To evaluate the feeding performance of infants with bronchopulmonary dysplasia (BPD) on paladai.

Methods: This cross-sectional study was performed in a level III neonatal unit in North India from March through August 2012. Nineteen infants (27-32 wk of gestation) were enrolled; 9 in BPD group (oxygen requirement for at least 28 d) and 10 in 'No BPD' group. Read More

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December 2018
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Transition of Children with Perinatally Acquired HIV-Infection into Adulthood: Social Outcome and Quality of Life.

Indian J Pediatr 2018 Dec 13. Epub 2018 Dec 13.

Asha Kirana Hospital, Hebbal Industrial Housing Area, Ring Road, Hebbal, Mysore 570016, Karnataka, India.

Objectives: In India, access to free anti-retroviral therapy has improved the survival of perinatally human immunodeficiency virus (HIV) infected children resulting in the transition of many such children to adulthood. This study aims to understand the social-outcomes and quality of life (QOL) among these adults.

Methods: This cross-sectional study was conducted in two tertiary HIV care centers in south India. Read More

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December 2018

Efficacy of Telephone Follow-Up in Children Tonsillectomy with Day Surgery.

Indian J Pediatr 2018 Dec 13. Epub 2018 Dec 13.

Department of ENT, Affiliated Renhe Hospital of China, Three Gorges University, Second Clinical Medical College of China, No. 410 Yiling Road, Yi Chang, Hubei, China.

Objective: Day surgery for tonsillectomy has become more and more popular in China. However, many parents face difficulties to cope up with the pain and side effects after surgery. The present study was aimed to examine the efficacy of telephone follow-up on children's post-discharge recovery after tonsillectomy. Read More

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December 2018
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Serum Retinol, Vitamin D and Zinc Levels in Under Five Children with Acute Lower Respiratory Tract Infections.

Indian J Pediatr 2018 Dec 13. Epub 2018 Dec 13.

Department of Pediatrics, Nalanda Medical College, Patna, 800013, India.

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December 2018
1 Read

Glacial changes in tropical climate amplified by the Indian Ocean.

Sci Adv 2018 Dec 12;4(12):eaat9658. Epub 2018 Dec 12.

National Center for Atmospheric Research, Climate and Global Dynamics Laboratory, 1850 Table Mesa Drive, Boulder, CO 80305, USA.

The mechanisms driving glacial-interglacial changes in the climate of the Indo-Pacific warm pool are poorly understood. Here, we address this question by combining paleoclimate proxies with model simulations of the Last Glacial Maximum climate. We find evidence of two mechanisms explaining key patterns of ocean cooling and rainfall change interpreted from proxy data. Read More

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December 2018

Effect of menstruation on girls and their schooling, and facilitators of menstrual hygiene management in schools: surveys in government schools in three states in India, 2015.

J Glob Health 2019 Jun;9(1):010408

Department of Clinical Sciences, Liverpool School of Tropical Medicine (LSTM), Liverpool, UK.

Background: Lack of menstrual knowledge, poor access to sanitary products and a non-facilitating school environment can make it difficult for girls to attend school. In India, interventions have been developed to reduce the burden of menstruation for school girls by government and non-governmental organizations (NGOs). We sought to identify challenges related to menstruation, and facilitators of menstrual management in schools in three states in India. Read More

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Injectable Biomimetic Hydrogels as Tools for Efficient T Cell Expansion and Delivery.

Front Immunol 2018 28;9:2798. Epub 2018 Nov 28.

Department of Tumor Immunology, Oncode Institute, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.

Biomaterial-based scaffolds are promising tools for controlled immunomodulation. They can be applied as three dimensional (3D) culture systems , whereas they may be used to dictate cellular localization and exert spatiotemporal control over cues presented to the immune system. As such, scaffolds can be exploited to enhance the efficacy of cancer immunotherapies such as adoptive T cell transfer, in which localization and persistence of tumor-specific T cells dictates treatment outcome. Read More

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November 2018

Prosthodontic rehabilitation of a sub-total maxillectomy defect with a definitive hollow obturator prosthesis using the modified lost-wax concept: A novel technique.

Natl J Maxillofac Surg 2018 Jul-Dec;9(2):225-228

Department of Prosthodontics, Christian Dental College, Ludhiana, Punjab, India.

Squamous cell carcinoma (SCC) of the oral cavity is relatively common in the Indian subcontinent with surgical resection and adjuvant radiotherapy/chemotherapy being the treatment modality of choice. Prosthetic rehabilitation with an obturator following resection is more economical and yields satisfactory results. Better patient acceptance and comfort necessitates hollowing the prosthesis to a great extent. Read More

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December 2018

Prevalence of mandibular fracture in patients visiting a tertiary dental care hospital in North India.

Natl J Maxillofac Surg 2018 Jul-Dec;9(2):123-128

Department of Oral Medicine and Radiology, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.

Background: Injuries of the maxillofacial complex represent one of the most important health problems worldwide. At present, in developing India, due to poor traffic sense, maxillofacial trauma and fractures are most epidemiologic diseases. Mandible is the largest and strongest facial bone and it is the second most commonly fractured bone. Read More

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December 2018

Evaluation of remineralization potential and mechanical properties of pit and fissure sealants fortified with nano-hydroxyapatite and nano-amorphous calcium phosphate fillers: An study.

J Conserv Dent 2018 Nov-Dec;21(6):681-690

Department of Prosthodontics, Maulana Azad Institute of Dental Sciences, New Delhi, India.

Objectives: The aim of this study was: (i) to formulate pit and fissure sealants (PFS) containing nano-hydroxyapatite (nHAP) filler; nHAP filler and silica co-filler; nHAP and nano-Amorphous Calcium Phosphate (nACP) co-filler, (ii) to evaluate physical properties; degree of conversion (DOC), curing depth (CD) and mechanical properties; microshear bond strength (MBS) of fortified PFS, and (iii) to assess remineralization potential and release of Ca and PO ions from newly synthesized sealants.

Materials And Methods: Four PFS were prepared using monomers with mixture of 35.5 wt % BisGMA, 35. Read More

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December 2018

Working governance for working land.

Science 2018 Dec;362(6420):1257

Global Development Institute, University of Manchester, Manchester M13 9PL, UK.

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December 2018
1 Read

Prof N. N. Wig........the "Living Legend" of Indian Psychiatry.

Asian J Psychiatr 2018 Dec;38:A5-A6

Department of Psychiatry, PGIMER, Chandigarh.

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December 2018

Optimization and Validation of a Chromatographic Method for the Quantification of Isoniazid in Urine of Tuberculosis Patients According to the European Medicines Agency Guideline.

Antibiotics (Basel) 2018 Dec 11;7(4). Epub 2018 Dec 11.

Química Bioanalítica, Departament de Química Física i Analítica, Escola Superior de Tecnologia i Ciències Experimentals, Universitat Jaume I, 12071 Castelló, Spain.

Isoniazid is a drug that is widely used against tuberculosis. However, it shows high interpatient variability in metabolism kinetics and clinical effect, which complicates the prescription of the medication and jeopardizes the success of the therapy. Therefore, in a specific patient, the pharmacokinetics of the drug must be elucidated to decide the proper dosage and intake frequency to make the drug suitable for therapeutic drug monitoring. Read More

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December 2018

Differing Contributions of Classical Risk Factors to Type 2 Diabetes in Multi-Ethnic Malaysian Populations.

Int J Environ Res Public Health 2018 Dec 10;15(12). Epub 2018 Dec 10.

Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, 2308, Australia.

The prevalence of type 2 diabetes is escalating rapidly in Asian countries, with the rapid increase likely attributable to a combination of genetic and lifestyle factors. Recent research suggests that common genetic risk variants contribute minimally to the rapidly rising prevalence. Rather, recent changes in dietary patterns and physical activity may be more important. Read More

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December 2018
2.063 Impact Factor

New Insights into the Occurrence and Toxin Profile of Ciguatoxins in Selvagens Islands (Madeira, Portugal).

Toxins (Basel) 2018 Dec 7;10(12). Epub 2018 Dec 7.

Faculty of Chemistry, Department of Analytical and Food Chemistry, University of Vigo, Campus Universitario de Vigo, 36310 Vigo, Spain.

Ciguatoxins (CTXs), endemic from tropical and subtropical regions of the Pacific and Indian Ocean and the Caribbean Sea, have caused several human poisonings during the last decade in Europe. Ciguatera fish poisonings (CFP) in Madeira and Canary Islands appear to be particularly related with consumption of fish caught close to Selvagens Islands, a Portuguese natural reserve composed of three small islands that harbor high fish biomass. In this study, fish specimens considered as potential vectors of CTXs were caught in Madeira and Selvagens archipelagos for toxins determination via sensitive liquid chromatography with tandem mass spectrometry detection (LC⁻MS/MS). Read More

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December 2018

Impact of intervention of biomass cookstove technologies and kitchen characteristics on indoor air quality and human exposure in rural settings of India.

Environ Int 2018 Dec 10;123:240-255. Epub 2018 Dec 10.

Department of Civil Engineering, Indian Institute of Technology Tirupati, Tirupati, Andhra Pradesh 517 506, India. Electronic address:

This study investigates the impact of increased levels of indoor air pollution (IAP) caused due to biomass burning in the rural households of Northern India. A comparative assessment of the impact of traditional cookstoves (TCS) and improved cookstoves (ICS) coupled with the characteristics of kitchen was conducted to estimate the PM (PM, PM, PM), CO/CO concentrations in the micro-environments of kitchen and living area of the households. The study incorporated both extensive and intensive real-time indoor air quality (IAQ) monitoring during the two cooking sessions of the day. Read More

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December 2018

A molecular dynamics based investigation reveals the role of rare Ribonuclease 4 variants in amyotrophic lateral sclerosis susceptibility.

Mutat Res 2018 Nov 29;813:1-12. Epub 2018 Nov 29.

Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India. Electronic address:

Missense mutations in certain genes of the Ribonuclease (RNASE) superfamily cause amyotrophic lateral sclerosis (ALS) through loss of either ribonucleolytic or nuclear translocation or both of these activities. While rare ANG/RNASE5 variants have been previously shown to be ALS causative, it is not yet known if any of the reported rare RNASE4 variants can also trigger ALS. The study aims to understand whether rare variants of RNASE4 can manifest ALS through similar loss-of-function mechanisms. Read More

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November 2018

A conformational switch from a closed apo- to an open holo-form equips the acyl carrier protein for acyl chain accommodation.

Biochim Biophys Acta Proteins Proteom 2018 Dec 10. Epub 2018 Dec 10.

Department of Biochemistry, University of Delhi South Campus, New Delhi 110021, India. Electronic address:

Acyl carrier proteins (ACPs) play crucial roles in the biosynthesis of fatty acids, non-ribosomal polypeptides and polyketides. The three-dimensional NMR structure of Leishmania major holo-LmACP, belonging to the type II pathway, has been reported previously, but the structure of its apo-form and its conformational differences with the holo-form remain to be explored. Here we report the crystal structures of apo-LmACP (wild-type and S37A mutant) at 2. Read More

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December 2018

Network-based features enable prediction of essential genes across diverse organisms.

PLoS One 2018 13;13(12):e0208722. Epub 2018 Dec 13.

Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology (IIT) Madras, Chennai - 600 036, India.

Machine learning approaches to predict essential genes have gained a lot of traction in recent years. These approaches predominantly make use of sequence and network-based features to predict essential genes. However, the scope of network-based features used by the existing approaches is very narrow. Read More

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December 2018

Primary Family Caregivers' Reasons for Disclosing Versus Not Disclosing a Cancer Diagnosis in India.

Cancer Nurs 2018 Dec 12. Epub 2018 Dec 12.

Author Affiliations: Department of Liberal Arts, Indian Institute of Technology Hyderabad, Hyderabad, India (Dr Chittem); and Department of Psychology, University of Sheffield (Dr Norman); and Department of Psychology, University of Sussex (Dr Harris), United Kingdom.

Background: Nondisclosure of cancer diagnosis continues to be practiced in India, with many family caregivers concealing it from patients in order to protect them from emotional distress.

Objective: The aim of this study was to explore Indian primary family caregivers' reasons for, and experiences of, disclosure versus nondisclosure to patients about their cancer diagnosis.

Methods: Indian disclosing (n = 8) and nondisclosing (n = 7) primary family caregivers participated in semistructured interviews exploring their reasons for disclosure versus nondisclosure of cancer diagnosis to their patient. Read More

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December 2018

Effect of impurities on the long-distance and Zhang-Rice dimers in the quantum magnet SrCuO.

J Phys Condens Matter 2018 Dec 13;31(3):035801. Epub 2018 Dec 13.

Department of Physics, Indian Institute of Science Education and Research, Pune 411008, Maharashtra, India.

We study the effect of impurities on the two types of spin-dimers in the hybrid chain-ladder spin 1/2 quantum magnet Sr[Formula: see text]Cu[Formula: see text]O[Formula: see text]. Four different impurities were used, namely, the non-magnetic Zn (0.0025 and 0. Read More

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December 2018

Unraveling the physical properties and superparamagnetism in anti-site disorder controlled FeTiSn.

J Phys Condens Matter 2018 Dec 13;31(4):045801. Epub 2018 Dec 13.

Discipline of Physics, Indian Institute of Technology Indore, Simrol, Indore 453 552, India.

With an aim to control the anti-site disorder between Fe and Ti atoms in the full Heusler alloy, Fe[Formula: see text]TiSn, we substitute a small percentage of Ti at Fe site to form the Fe[Formula: see text]Ti[Formula: see text]Sn ([Formula: see text]) series. Using the incident x-rays tuned to the Fe K-edge absorption energy, we record the high resolution synchrotron x-ray diffraction profiles and unambiguously show the reduction in anti-site disorder. In particular, the Fe-Ti anti-site disorder decreases up to an excess Ti content of 0. Read More

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December 2018

Synthesis of Cyclopropanoids via Substrate-Based Cyclization Pathways.

Org Lett 2018 Dec 13. Epub 2018 Dec 13.

Organic Synthesis and Catalysis Lab, Department of Chemical Sciences , Indian Institute of Science Education and Research (IISER) Mohali , Sector 81 , Manauli PO, S. A. S. Nagar, Punjab 140306 , India.

A series of unexpected reactions triggered by the dimethyloxosulfonium methylide led to the discovery of unconventional approaches for the synthesis of cyclopropa-fused tetralones and indeno-spirocyclopropanes. These highly functionalized structures were further elaborated in one step to privileged scaffolds such as tetralones, indenones, and fluorenones. As a whole, the results presented herein establish new diversity-oriented folding pathways. Read More

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December 2018

Metal- and Hydride-Free Pentannulative Reductive Aldol Reaction.

Org Lett 2018 Dec 13. Epub 2018 Dec 13.

Organic Synthesis and Catalysis Lab, Department of Chemical Sciences , Indian Institute of Science Education and Research (IISER) Mohali , Sector 81 , Manauli PO, S. A. S. Nagar, Punjab 140306 , India.

Traditionally, the reductive aldol reaction is a metal-catalyzed and hydride-promoted coupling between enones and aldehydes. We present a phosphine-mediated diastereoselective intramolecular reductive aldol reaction of α-substituted dienones and aldehydes, which is metal-free and hydride-free. The synthetic utility of the reductive aldol adducts is demonstrated by elaborating them in one step to indeno[1,2- b]furanones, indeno[1,2- b]pyrans, and dibenzo[ a, h]azulen-8-ones. Read More

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December 2018

Drug Discovery for Kinetoplastid Diseases: Future Directions.

ACS Infect Dis 2018 Dec 13. Epub 2018 Dec 13.

Novartis Institute for Tropical Diseases (NITD) , 5300 Chiron Way , Emeryville , California 94608 , United States.

Kinetoplastid parasites have caused human disease for millennia. Significant achievements have been made toward developing new treatments for leishmaniasis (particularly on the Indian subcontinent) and for human African trypanosomiasis (HAT). Moreover, the sustained decrease in the incidence of HAT has made the prospect of elimination a tantalizing reality. Read More

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December 2018

Transition-metal-catalyzed site-selective C7-functionalization of indoles: advancement and future prospects.

Chem Commun (Camb) 2018 Dec 13. Epub 2018 Dec 13.

Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.

C7-Decorated indoles are important structural motifs present in a plethora of bioactive and pharmaceutical compounds. Early stage developments for C7 modifications were realized through directed metallation (DOM) and subsequent quenching with suitable electrophiles or by halogenation with Cu(ii) halides. Direct C-7 functionalization of indoles is comparatively difficult compared to functionalization at C-2 and C-3 positions owing to the inherent reactivity of the pyrrole-type ring. Read More

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December 2018

Computational and in-vitro validation of natural molecules as potential Acetylcholinesterase inhibitors and neuroprotective agents.

Curr Alzheimer Res 2018 Dec 12. Epub 2018 Dec 12.

Department of Biotechnology and Bioinformatics, Jaypee University of Information Technology, Waknaghat, Solan, Himachal Pradesh - 173234. India.

Background: Cholinesterase inhibitors are the first line of therapy for the management of Alzheimer's disease (AD), however, it is now established that they provide only temporary and symptomatic relief, besides, having several inherited side-effects. Therefore, an alternative drug discovery method is to identify new and safer 'disease-modifying drugs'.

Methods: Herein, we screened 646 small molecules of natural origin having reported pharmacological and functional values through in-silico docking studies to predict safer neuromodulatory molecules with potential to modulate acetylcholine metabolism. Read More

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December 2018