683,519 results match your criteria In Vitro Cellular & Developmental Biology - Animal [Journal]


University athletes and changes in cardiac geometry: insight from the 2015 Gwangju Summer Universiade.

Eur Heart J Cardiovasc Imaging 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiovascular Medicine, Chonnam National University Hospital, 42 Jebong-ro, Dong-gu, Gwangju, Korea.

Aims: There is a paucity of data regarding the changes of cardiac geometry in highly trained international and multiracial university athletes. We aimed to investigate the incidence of structural cardiac abnormalities and changes of cardiac geometry in highly trained university athletes.

Methods And Results: Comprehensive echocardiographic studies were performed in 1185 university athletes through the Check-up Your Heart Program during the 2015 Gwangju Summer Universiade. Read More

View Article
December 2018

Hypertension in chronic kidney disease: Nephrology Dialysis Transplantation notable 2017 advances.

Nephrol Dial Transplant 2018 Dec 12. Epub 2018 Dec 12.

Department of Medicine, Indiana University School of Medicine and Richard L. Roudebush Veterans Administration Medical Center, Indianapolis, IN, USA.

View Article
December 2018

Magnesium status and supplementation influence vitamin D status and metabolism: results from a randomized trial.

Am J Clin Nutr 2018 Dec;108(6):1249-1258

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine, Vanderbilt University, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN.

Background: Previous in vitro and in vivo studies indicate that enzymes that synthesize and metabolize vitamin D are magnesium dependent. Recent observational studies found that magnesium intake significantly interacted with vitamin D in relation to vitamin D status and risk of mortality. According to NHANES, 79% of US adults do not meet their Recommended Dietary Allowance of magnesium. Read More

View Article
December 2018

Occlusion Outside the Norm: A Unique Case of the Pulseless, Well-Perfused Hand Following Closed Humeral Shaft Fracture.

Orthopedics 2018 Dec 11:1-3. Epub 2018 Dec 11.

Transient arterial injury is a common complication encountered in the management of pediatric supracondylar humerus fractures, often presenting as a pulseless hand that appears well perfused, also known as the "pink, pulseless hand." Arterial injuries in pediatric humeral shaft fractures, on the other hand, are exceedingly rare, especially in closed fractures. The authors report a rare case of a humeral shaft fracture presenting as a pink, pulseless hand. Read More

View Article
December 2018

Total Elbow Arthroplasty Versus Open Reduction and Internal Fixation for the Management of Distal Humerus Fractures in the Elderly.

Orthopedics 2018 Dec 11:1-6. Epub 2018 Dec 11.

Distal humerus fractures, which are challenging injuries seen in geriatric patients, are often repaired using open reduction and internal fixation or total elbow arthroplasty. This updated meta-analysis, which includes more recent open reduction and internal fixation techniques, examined outcomes following distal humerus fractures repaired using open reduction and internal fixation vs total elbow arthroplasty. Although distal humerus fractures treated with total elbow arthroplasty achieved statistically higher functional scores relative to those treated with open reduction and internal fixation, this difference was not clinically significant. Read More

View Article
December 2018

Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays.

PLoS One 2018 12;13(12):e0207140. Epub 2018 Dec 12.

R&D Alternative Discovery and Development, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom.

Atonal homolog 1 (Atoh1) is a basic helix-loop-helix 9 (bHLH) transcription factor acting downstream of Notch and is required for the differentiation of sensory hair cells in the inner ear and the specification of secretory cells during the intestinal crypt cell regeneration. Motivated by the observations that the upregulation of Atoh1 gene expression, through genetic manipulation or pharmacological inhibition of Notch signaling (e.g. Read More

View Article
December 2018

Treatment of Young Femoral Neck Fractures.

J Orthop Trauma 2019 Jan;33 Suppl 1:S1-S6

Department Orthopaedic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC.

Femoral neck fractures in the physiologically young patient are challenging injuries to manage. A tenuous blood supply and the intrasynovial nature of the fracture create a challenging biological environment. To make matters worse, the biomechanics are equally problematic. Read More

View Article
January 2019

No difference in outcomes in a matched cohort of operative versus nonoperatively treated displaced medial epicondyle fractures.

J Pediatr Orthop B 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopedic Surgery, Children's Hospital of Colorado.

The purpose of our study was to compare the treatment outcomes and complications between operatively and nonoperatively treated displaced medial epicondyle fractures. Pediatric patients treated for an acute, displaced medial epicondyle fracture between 2005 and 2015 were retrospectively reviewed. A total of 22 operative participants were matched to 22 nonoperative participants, with an average displacement of 9. Read More

View Article
December 2018
1 Read

Engaging in the prevention of pressure injuries in spinal cord injury: A qualitative study of community-dwelling individuals' different styles of prevention in Switzerland.

J Spinal Cord Med 2018 Dec 12:1-10. Epub 2018 Dec 12.

a Department of Health Sciences and Health Policy , University of Lucerne and Swiss Paraplegic Research , Lucerne/Nottwil , Switzerland.

Context: Spinal cord injury (SCI) is a complex chronic condition with multiple self-management requirements and a high prevalence of complications. Pressure injuries (PIs) are among the most common ones and represent a frequent reason for re-hospitalization. This study aimed to identify styles of prevention that individuals with SCI adopt to deal with the risk of developing PIs. Read More

View Article
December 2018

A comparison of urodynamic findings between patients with complete and incomplete traumatic spinal cord injuries.

J Spinal Cord Med 2018 Dec 12:1-6. Epub 2018 Dec 12.

c The Department of Physical Medicine and Rehabilitation , Hitit University Medical School , Çorum , Turkey.

Objective: To compare urodynamic findings between patients with complete and incomplete traumatic spinal cord injuries (SCI) and to determine whether it is important to test with urodynamic study in patients with incomplete SCI.

Design: Retrospective study Setting: Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey Participants: A total of 66 patients with 36 complete and 30 incomplete traumatic SCI were included in the study, from July 2012 to September 2014.

Interventions: Urodynamic study Outcome Measures: Maximum cystometric capacity (MCC) , vesicle pressure at MCC, detrusor function (detrusor overactivity or not), bladder complience, bladder storage and emptying disorders, post-void residual volume (PVR) and bladder emptying method were recorded. Read More

View Article
December 2018
2 Reads

The effect of leisure coping on depressive symptoms among individuals with depression: examination of potential confounding effects of physical activity and extraversion.

Psychol Health Med 2018 Dec 12:1-13. Epub 2018 Dec 12.

c School of Public Health , Indiana University , Bloomington , IN , USA.

Clinically significant depression has been consistently identified as a phenomenon directly linked to stress and stress coping. Leisure behavior as purposeful coping strategy (i.e. Read More

View Article
December 2018

Incidence and type of health care associated injuries among nursing students: an experience in northern Italy.

Acta Biomed 2018 Dec 7;89(7-S):41-49. Epub 2018 Dec 7.

Corso di Laurea in Infermieristica Università di Bologna - Faenza.

Background And Aim Of The Study: Nursing students are at high risk of injury while on clinical placement. The incidence of injury is three times higher in comparison to other healthcare workers, with a prevalence ranging from 25% up to 33,2%. Lack of knowledge and of experience in delivering nursing care, anxiety and unfamiliarity with the clinical environment all represent risk factors for injury. Read More

View Article
December 2018

Anatomical Risk Factors of Anterior Cruciate Ligament Injury.

Chin Med J (Engl) 2018 Dec;131(24):2960-2967

Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215004, China.

Background: Nowadays, the anterior cruciate ligament (ACL) injury has been one of the most common diseases of the knee joint. The relationships between the ACL injury and the anatomical structures are still controversial. This study aimed to identify the anatomical risk factors of ACL injury by magnetic resonance imaging (MRI) of the knee. Read More

View Article
December 2018
4 Reads

Risk behaviors contributing to recent serious unintentional injuries among school-going adolescent boys in Kolkata: Application of zero-inflated count model.

Indian J Public Health 2018 Oct-Dec;62(4):265-270

Post-Graduate Trainee, Department of Community Medicine, Medical College and Hospital, Kolkata, West Bengal, India.

Background: Unintentional injuries have become a major noncommunicable disease burden, especially among the adolescents.

Objective: The current study was conducted to estimate the effect of different aspects of daily activities of adolescence for sustaining serious unintentional injuries in the past 1 year.

Methods: A cross-sectional survey with multistage sampling with validated pretested questionnaire was done among the school-going adolescent boys in Kolkata. Read More

View Article
December 2018

Peripheral oxytocin and vasopressin modulates regional brain activity differently in men and women with schizophrenia.

Schizophr Res 2018 Dec 6;202:173-179. Epub 2018 Jul 6.

Department of Radiology, West China Hospital of Sichuan University, Chengdu, People's Republic of China; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, United States of America; Department of Psychiatry, University of Cincinnati, United States of America.

Background: Oxytocin (OT) and arginine vasopressin (AVP) exert sexually dimorphic effects on cognition and emotion processing. Abnormalities in these hormones are observed in schizophrenia and may contribute to multiple established sex differences associated with the disorder. Here we examined sex-dependent hormone associations with resting brain activity and their clinical associations in schizophrenia patients. Read More

View Article
December 2018

Utility of early active motion for flexor tendon repair with concomitant injuries: A multivariate analysis.

Injury 2018 Dec 22;49(12):2248-2251. Epub 2018 Oct 22.

Department of Orthopaedic Surgery, Nagoya Ekisaikai Hospital, 4-66 Shonen-Cho, Nakagawa-Ku, Nagoya, 454-8502, Japan.

Introduction: Flexor tendon injury often occurs with concomitant injuries such as fracture, vascular injury, and extensor tendon injury. These injuries are repaired independently, without a comprehensive strategy. We aimed to identify the effect of concomitant injuries and treatment choice on the outcome of flexor tendon repair. Read More

View Article
December 2018

Harm Reduction Strategies and Disinhibitors Among Women Who Use Heroin.

Int J Offender Ther Comp Criminol 2018 Dec 12:306624X18818682. Epub 2018 Dec 12.

2 University of Alabama at Birmingham, USA.

People who use illicit drugs face significant physical risks in the acquisition, use, and aftermath of their use. This is particularly the case among those who use heroin in view of recent spikes in heroin-associated overdoses, injuries, and deaths. Using a restrictive deterrence framework, we identify the risks that women associate with chronic heroin use and the ways they seek to manage those risks. Read More

View Article
December 2018

Pediatric open-globe injury in a university-based tertiary hospital.

Eur J Ophthalmol 2018 Dec 12:1120672118818013. Epub 2018 Dec 12.

1 Department of Ophthalmology, King Abdulaziz University Hospital, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Background:: To investigate epidemiology, etiology, and outcomes after repair of pediatric open-globe injury.

Methods:: We retrospectively reviewed medical records of patients ⩽18 years who underwent primary open-globe repair.

Results:: A total of 213 patients were identified. Read More

View Article
December 2018

Sports Injuries: Diagnosis, Prevention, Stem Cell Therapy, and Medical Sport Strategy.

Adv Exp Med Biol 2018 Dec 12. Epub 2018 Dec 12.

Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Sports injuries diagnosis, prevention, and treatment are the most important issues of sports medicine. Fortunately, sports injuries are often treated effectively, and people with damage recover and return to the sport in a satisfactory condition. Meanwhile, many sports injuries and complications can be prevented. Read More

View Article
December 2018

Optical coherence tomography imaging of melanoma skin cancer.

Lasers Med Sci 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

No consensus guidelines exist on the use of optical coherence tomography (OCT) for diagnosis of cutaneous melanoma. The objectives of this review are to provide a descriptive review of the literature on characteristics of cutaneous melanomas seen on high-definition OCT (HD-OCT), speckle variance OCT (SV-OCT), and conventional OCT and to compare their diagnostic ability with that of histopathology. A review of PubMed and Google Scholar identified all available literature on OCT in melanoma skin cancer that included all in vivo and ex vivo studies on human or human tissues and excluded all studies on non-human subjects or animal studies. Read More

View Article
December 2018
1 Read

Isolation and Identification of Murine Bone Marrow-Derived Macrophages and Osteomacs from Neonatal and Adult Mice.

Methods Mol Biol 2018 Dec 12. Epub 2018 Dec 12.

Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

Hematopoietic stem cells (HSCs) are regulated by multiple components of the hematopoietic niche, including bone marrow-derived macrophages and osteomacs. However, both macrophages and osteomacs are phenotypically similar. Thus, specific phenotypic markers are required to differentially identify the effects of osteomacs and bone marrow macrophages on different physiological processes, including hematopoiesis and bone remodeling. Read More

View Article
December 2018

Wnt/β-catenin in ischemic myocardium: interactions and signaling pathways as a therapeutic target.

Heart Fail Rev 2018 Dec 12. Epub 2018 Dec 12.

Department of biochemistry and hematology, faculty of medicine, Semnan University of Medical Sciences, Semnan, Iran.

Cardiovascular disease (CVD) is still a factor of mortality in the whole world. Through canonical and noncanonical pathways and with different receptors, the Wnt/β-catenin signaling pathway plays an essential role in response to heart injuries. Wnt regulates the mobilization and proliferation of cells in endothelium and epicardium in an infarcted heart. Read More

View Article
December 2018

Evaluation of the effects of an oral notch inhibitor, crenigacestat (LY3039478), on QT interval, and bioavailability studies conducted in healthy subjects.

Cancer Chemother Pharmacol 2018 Dec 11. Epub 2018 Dec 11.

Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, 46285, USA.

Purpose: Crenigacestat (LY3039478) is a Notch inhibitor currently being investigated in advanced cancer patients. Conducting clinical pharmacology studies in healthy subjects avoids nonbeneficial drug exposures in cancer patients and mitigates confounding effects of disease state and concomitant medications.

Methods: Three studies were conducted in healthy subjects, assessing safety, pharmacokinetics, effect on QT interval, and relative and absolute bioavailability of crenigacestat. Read More

View Article
December 2018

Trifecta outcome of ureteral reconstruction in iatrogenic injury and non-iatrogenic ureteral lesions: a 10-year experience at a tertiary referral center.

World J Urol 2018 Dec 11. Epub 2018 Dec 11.

Department of Urology, National Taiwan University Hospital, Taipei, Taiwan.

Purpose: To analyze the trifecta outcome (functional, anatomical, and surgical aspects) of surgical reconstruction for ureteral lesions and investigate the factors affecting the success rate of such reconstruction.

Methods: We retrospectively reviewed the data of patients who underwent ureteral reconstruction at our institute between March 2007 and November 2016. Patient profiles, surgical methods, complications, ureteral stenting, laboratory data, and image studies were collected. Read More

View Article
December 2018

Clinical and radiologic outcomes of two patellar resection techniques during total knee arthroplasty: a prospective randomized controlled study.

Int Orthop 2018 Dec 11. Epub 2018 Dec 11.

Institution of Sports Medicine, Beijing Key Laboratory of Sports Injuries, Peking University Third Hospital, No. 49 North, Garden Road, Haidian, Beijing, 100191, China.

Purpose: A cutting guide technique for patella resurfacing in total knee arthroplasty was expected to result in less patellofemoral syndromes. The aim of this study was to identify differences in the patellofemoral function, clinical outcomes, and radiographic parameters between the freehand and cutting guide patellar resection techniques in patients undergoing total knee arthroplasty.

Methods: A prospective randomized controlled trial was conducted. Read More

View Article
December 2018
2 Reads

Occult injuries of the contralateral sacroiliac joint in operatively treated pelvis fractures: incidence, root cause analysis, and proposal of treatment algorithm.

Int Orthop 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopaedics, Denver Health Medical Center, 777 Bannock Street, Denver, CO, 80204, USA.

Purpose: To determine the most common injury patterns, root cause, and the frequency with which unrecognized contralateral posterior ring injury occurs in patients presenting with surgically treated pelvic fractures.

Methods: The medical records of 73 patients presenting to our level I trauma center (52 male and 21 female patients; mean age 41.8 years; range 18-89 years) with surgically treated pelvic ring fractures between January 1, 2016 and January 1, 2018 were reviewed. Read More

View Article
December 2018

Diagnosis of diaphragm injuries using modern 256-slice CT scanners: too early to abandon operative exploration.

Trauma Surg Acute Care Open 2018 26;3(1):e000251. Epub 2018 Nov 26.

Division of Acute Care Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Background: Missed injury of the diaphragm may result in hernia formation, enteric strangulation, and death. Compounding the problem, diaphragmatic injuries are rare and difficult to diagnose with standard imaging. As such, for patients with high suspicion of injury, operative exploration remains the gold standard for diagnosis. Read More

View Article
November 2018

Decreased mortality, laparotomy, and embolization rates for liver injuries during a 13-year period in a major Scandinavian trauma center.

Trauma Surg Acute Care Open 2018 5;3(1):e000205. Epub 2018 Nov 5.

Department of Traumatology, Oslo University Hospital Ulleval, Oslo, Norway.

Background: Although non-operative management (NOM) has become the treatment of choice in hemodynamically normal patients with liver injuries, the optimal management of Organ Injury Scale (OIS) grades 4 and 5 injuries is still controversial. Oslo University Hospital Ulleval (OUHU) has since 2008 performed angiography only with signs of bleeding. Simultaneously, damage control resuscitation was implemented. Read More

View Article
November 2018
1 Read

Lumbar Spine Injuries: Primary Prevention in Amateur and Professional Golf Players.

Sports Med Int Open 2018 Nov 16;2(6):E179-E184. Epub 2018 Nov 16.

Golf Biomechanic Academy, Teaching, Pforzheim, Germany.

In the sport of golf, there is no standard teaching method or swing technique even though golf is known for overuse injuries. This prospective study was to analyze classic swing kinematics in comparison with the Free-Release method and to define a physiological golf swing. Two hundred eighty-three players, age 50-59 years, were included in the study. Read More

View Article
November 2018
1 Read

Pre-season Fitness Level and Injury Rate in Professional Soccer - A Prospective Study.

Sports Med Int Open 2018 Jun 22;2(3):E84-E90. Epub 2018 Aug 22.

Child Health & Sports Center, Meir Medical Center, Pediatrics, Sackler School of Medicine, Tel Aviv University Kfar Saba, Israel.

The aim of the present study was to assess prospectively the effect of pre-season fitness on injury rate during the competitive season among professional soccer players. Thirty-one players participated in the study during two consecutive competitive seasons (2015-16 and 2016-17; a squad of 22 players in each season). During the 6-week pre-season training period (8 training sessions and a friendly match every week, 14-18 training hours/week) there was a significant improvement in VO max, a significant increase in ideal and total sprint time and no change in vertical jump, flexibility and repeated sprint-test performance decrement. Read More

View Article

Current Soccer Footwear, Its Role in Injuries and Potential for Improvement.

Sports Med Int Open 2018 Apr 25;2(2):E52-E61. Epub 2018 May 25.

Laboratoire de Biomécanique Appliquée, Aix-Marseille Univ, IFSTTAR, LBA UMR_T24, Marseille, France.

Soccer is the most popular sport in the world and generates great financial revenue. It is also a sport whose practice has evolved considerably in terms of intensity and commitment, and in which the intrinsic risk of injury (not directly related to an interaction with the environment) is particularly high. In this context, the cleated shoe as a major component of soccer equipment may play a key role in the overexposure to injury. Read More

View Article

Pilot evaluation of an objective structured assessment of technical skills tool for chest tube insertion.

GMS J Med Educ 2018 15;35(4):Doc48. Epub 2018 Nov 15.

University of Heidelberg, Department of General, Visceral, and Transplantation Surgery, Heidelberg, Germany.

Chest tube insertion is a standard intervention for management of various injuries of the thorax. Efficient clinical training of this and similar bed-side procedures is equally demanded and improvable. Here, we propose a nouveau means of assessment and feedback using an Objective Structured Assessment of Technical Skills (OSATS) tool. Read More

View Article
November 2018

Inflammation-Nature's Way to Efficiently Respond to All Types of Challenges: Implications for Understanding and Managing "the Epidemic" of Chronic Diseases.

Front Med (Lausanne) 2018 27;5:316. Epub 2018 Nov 27.

School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Newcastle, NSW, Australia.

Siloed or singular system approach to disease management is common practice, developing out of traditional medical school education. Textbooks of medicine describe a huge number of discrete diseases, usually in a systematic fashion following headings like etiology, pathology, investigations, differential diagnoses, and management. This approach suggests that the body has a multitude of ways to respond to harmful incidences. Read More

View Article
November 2018
1 Read

Testicular Rupture or Testicular Fracture? A Case Report and Literature Review.

Case Rep Urol 2018 14;2018:1323780. Epub 2018 Nov 14.

Department of Urology, St George's Hospital, London, UK.

Testicular trauma is relatively uncommon. However, severe injuries can result in many complications and should be carefully diagnosed and managed. We present a case of testicular fracture diagnosis made by ultrasonography. Read More

View Article
November 2018

Current and Emerging Therapeutic Options for Gastroparesis.

Gastroenterol Hepatol (N Y) 2018 Nov;14(11):639-645

Dr Myint, Dr Rieders, and Dr Tashkandi are gastroenterology fellows in the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center and are affiliated with Medical Faculty Associates, both in Washington, DC. Dr Borum is a professor of medicine at George Washington University School of Medicine in Washington, DC; director of the Division of Gastroenterology and Liver Diseases at George Washington University Medical Center; and is affiliated with Medical Faculty Associates. Dr Koh and Dr Stephen are in private practice in Silver Spring, Maryland. Dr Doman is a clinical professor of medicine at George Washington University School of Medicine and is in private practice in Silver Spring, Maryland.

Gastroparesis is a complex, debilitating dysmotility disorder with challenging symptom management. A diagnosis of gastroparesis is based on objectively delayed gastric emptying in the absence of mechanical obstruction. Given the limited efficacy of treatment options and serious side effects, significant research continues for therapeutic options for gastroparesis. Read More

View Article
November 2018

Mechanism research on a bioactive resveratrol- PLA-gelatin porous nano-scaffold in promoting the repair of cartilage defect.

Int J Nanomedicine 2018 22;13:7845-7858. Epub 2018 Nov 22.

Department of Orthopedics and Trauma, Peking University People's Hospital, Beijing, China,

Background: Articular cartilage defects are difficult to treat, but drug-loaded tissue engineering scaffolds provide a possible treatment option for these types of injuries.

Purpose: In this study, we designed a bioactive resveratrol-PLA-gelatin porous nano-scaffold using electrospinning, freeze drying, and uniform dispersion techniques to repair articular cartilage defects, and then investigated the possible mechanism behind the successful repair.

Methods: We established an articular cartilage defect rat model with a 2 mm diameter wound in the middle of the knee joint femoral condyle non-weight-bearing area, with a depth reaching the full thickness of the subchondral bone. Read More

View Article
November 2018

Positive airway pressure for sleep-disordered breathing in acute quadriplegia: a randomised controlled trial.

Thorax 2018 Dec 11. Epub 2018 Dec 11.

Department of Respiratory and Sleep Medicine, Royal North Shore Hospital, St Leonards, New South Wales, Australia.

Rationale: Highly prevalent and severe sleep-disordered breathing caused by acute cervical spinal cord injury (quadriplegia) is associated with neurocognitive dysfunction and sleepiness and is likely to impair rehabilitation.

Objective: To determine whether 3 months of autotitrating CPAP would improve neurocognitive function, sleepiness, quality of life, anxiety and depression more than usual care in acute quadriplegia.

Methods And Measurements: Multinational, randomised controlled trial (11 centres) from July 2009 to October 2015. Read More

View Article
December 2018

Are Traumatic Brain Injuries Associated With Criminality After Taking Account of Childhood Family Social Status and Disruptive Behaviors?

J Neuropsychiatry Clin Neurosci 2018 Dec 12:appineuropsych18040094. Epub 2018 Dec 12.

From the Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada (GIG, AP); the Centre de Recherche de l'Institut Universitaire de Santé Mentale de Montréal, Département de Psychiatrie et Addictologie, Université de Montréal (MPR, SH); the Groupe de Recherche sur l'Inadaptation Sociale, Montréal (FV, RET, SH); and the School of Health Care and Social Welfare, Mälardalens University, Västerås, Sweden (PL).

Objective:: The authors aimed to elucidate the links between traumatic brain injuries (TBIs) and criminal convictions in a sample of 724 Canadian males with and without criminal records followed up to age 24.

Methods:: Prospectively collected data were analyzed to determine whether prior TBIs predicted subsequent criminal convictions after taking account of family social status (FSS) and childhood disruptive behaviors. At age 24, diagnoses of TBIs were extracted from health records and convictions from official criminal records. Read More

View Article
December 2018

Additive Contributions of Social Information Processing and Economic Stress to Maltreatment Risk in Disadvantaged Rural Fathers.

Child Maltreat 2018 Dec 11:1077559518815616. Epub 2018 Dec 11.

1 Department of Psychology, The Pennsylvania State University, PA, USA.

Child maltreatment is a critical concern in rural communities. Fathers perpetrate a substantial proportion of maltreatment cases and are overrepresented as perpetrators of severe physical abuse and fatalities. Despite this heightened risk, little research has examined risk of abuse and neglect among fathers in rural areas. Read More

View Article
December 2018

Evaluation of mRNA Expression Levels of TNFα, TNFR1 and IL1β in Lung Tissue 20 Years after Sulfur-mustard Exposure.

Iran J Allergy Asthma Immunol 2018 Aug 12;17(4):379-387. Epub 2018 Aug 12.

Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran AND Department of Respiratory, Pasteur Institute of Iran, Tehran, Iran.

Despite many years having passed since exposure to sulfur mustard (SM) gas, there are many exposed subjects who are still suffering from delayed pulmonary complications. The levels of pro-inflammatory cytokines in the lung of these subjects have not been investigated in delay phase. In this study, we evaluated mRNA expression of pro-inflammatory  cytokines (tumor necrosis factor alpha (TNFα), tumor necrosis factor receptor type 1 (TNFR1), and interleukin 1 beta (IL-1β)  ) in lung biopsy of SM-exposed subjects and compared them with control (non-exposed) subjects. Read More

View Article

A case of acute thrombotic occlusion of the popliteal artery occurring immediately after the total knee arthroplasty recanalized by ballooning alone.

J Cardiol Cases 2013 Dec 29;8(6):190-192. Epub 2013 Oct 29.

Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan.

Arterial complications associated with total knee arthroplasty are rare but occasionally life-threatening. Although popliteal artery injuries have been repaired by bypass surgery historically, there are potentially multiple useful methods for the restoration. In this report, we describe a case of acute thrombotic occlusion of the popliteal artery occurring immediately after total knee arthroplasty, and successfully repaired by endovascular therapy with endoluminal balloon inflation. Read More

View Article
December 2013

A case of late iliac arterial thrombosis due to component migration after revision total hip arthroplasty.

J Cardiol Cases 2014 Nov 28;10(5):196-199. Epub 2014 Aug 28.

Division of Orthopedics, Nagoya City East Medical Center, Nagoya, Japan.

Although vascular injuries associated with primary and revision total hip arthroplasty are infrequent, these complications can have devastating effects that can lead to morbidity and even mortality. A few previous reports have described embolic distal limb ischemia secondary to a failed and migrated acetabular implant in discontinuity with the pelvis. We present a rare case in which a support ring from a failed and migrated acetabular cage construct led to injury of the common femoral artery. Read More

View Article
November 2014

Burn-associated delayed dilated cardiomyopathy evaluated by cardiac PET and SPECT: Report of a case.

J Cardiol Cases 2014 Nov 10;10(5):180-183. Epub 2014 Aug 10.

Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.

Dilated cardiomyopathy is a delayed-onset and rarely reported cardiac complication of burn injury although the mechanism remains unclear. We thus report a case of dilated cardiomyopathy following severe burn injury, in which technetium 99m sestamibi single-photon emission computed tomography (SPECT), iodine-123 beta-methyl-iodophenylpentadecanoic acid SPECT and F-fluorodeoxyglucose positron emission tomography (PET) were performed to evaluate the pathophysiologic condition in combination with cardiac catheterization and myocardial biopsy. The cardiac PET and SPECT images showed reduced myocardial blood flow, decreased fatty acid metabolism, and increased glucose utilization in the left ventricular lateral wall in spite of normal coronary angiography, no significant cardiac fibrosis, and inflammatory cell infiltration, which suggests that myocardial ischemia due to microcirculatory disturbance in hypermetabolic state associated with burn injury might be a causative mechanism of dilated cardiomyopathy in this case. Read More

View Article
November 2014

Traumatic transection of the left anterior descending artery caused by a projectile.

J Cardiol Cases 2012 Jun 31;5(3):e140-e142. Epub 2012 Mar 31.

University of Miami Miller School of Medicine, Department of Internal Medicine, Division of Cardiology, Miami, FL, USA.

Background: Coronary lesions caused by penetrating trauma are rare and associated with high mortality rates. Management depends on factors such as the location of the affected vessel and the degree of myocardial dysfunction. We present a case of penetrating cardiac trauma resulting in the subsequent occlusion of the distal left anterior descending artery (LAD) leading to the development of an apical myocardial infarct. Read More

View Article

Acute coronary syndrome and cerebral arterial gas embolism in a scuba diver.

J Cardiol Cases 2011 Feb 14;3(1):e22-e25. Epub 2010 Dec 14.

Centre de Médecine Hyperbare, Pôle RUSH, CHU Sainte Marguerite, Marseille, France.

Background: Pulmonary barotrauma is a rare but feared complication of scuba diving, with around 30% mortality.

Objective: We report an uncommon case of pulmonary barotrauma complicated by arterial gas embolism with both coronary and neurological ischemic injuries after scuba diving.

Case Report: A 46-year-old-man was admitted to our hospital for acute coronary syndrome and stroke following a scuba dive. Read More

View Article
February 2011

Diagnosis of A3 Pulley Injuries Using Ultrasound.

Sportverletz Sportschaden 2018 Dec 11;32(4):251-259. Epub 2018 Dec 11.

Department of Sportsmedicine, Department of Orthopedic and Trauma Surgery, Klinikum Bamberg, Bamberg, Germany.

Rationale And Objectives:  Pulley ruptures are the most common injuries in sport climbing. Ruptures of the A2 and A4 pulleys have been studied extensively, and ultrasound has proven to be a highly sensitive and specific tool for their diagnosis. However, the correct diagnosis of A3 pulley ruptures continues to be a challenge. Read More

View Article
December 2018

Renal Functions and Prognosis Stratification in Chronic Heart Failure Patients and the Importance of Neutrophil Gelatinase-Associated Lipocalin.

Kidney Blood Press Res 2018 Dec 7;43(6):1865-1877. Epub 2018 Dec 7.

Department of Internal Cardiology Medicine, Faculty Hospital Brno, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

Background/aims: The rate of incidence and prevalence of acute kidney injury is increasing due to an increased number of patients with heart failure. Therefore it is very pertinent to early detect the level of renal injuries and to make necessary heart failure predictions. Thus the aim of this study is to determine renal functions and prognosis stratification in chronic heart failure patients and importance of Neutrophil Gelatinase-Associated Lipocalin (NGAL), an early diagnostic marker of acute kidney injury, as well as stratification of cardiovascular risk in heart failure patients. Read More

View Article
December 2018
1 Read

Investigation of efficiency of a novel, zinc oxide loaded TEMPO-oxidized cellulose nanofiber based hemostat for topical bleeding.

Int J Biol Macromol 2018 Dec 8. Epub 2018 Dec 8.

Department of Regenerative Medicine, College of Medicine, Soonchunhyang University Cheonan-31151, Republic of Korea; Institute of Tissue Regeneration, College of Medicine, Soonchunhyang University 366-1, Cheonan 31151, Republic of Korea. Electronic address:

Lethal bleeding due to street accidents, natural calamities, orthopedic/dental surgeries, organ transplantation and household injuries, is the leading cause of morbidity and mortality. In the current study, zinc oxide (ZnO) was incorporated in TEMPO-oxidized cellulose nanofiber (TOCN) and polyethylene glycol (PEG) polymer system for hemorrhage control by freeze drying method. SEM and XRD data showed the presence of ZnO in the porous structure. Read More

View Article
December 2018
1 Read
  • Page 1 of 13671