210,195 results match your criteria Implementation Science [Journal]


Comparing two high correlation models to test the mechanical stability of Americium-II.

J Phys Condens Matter 2018 Dec 11. Epub 2018 Dec 11.

Instituto de Fisica, Benemerita Universidad Autonoma de Puebla, 18 sur y av. San Claudio, CU, San Manuel, Puebla, Puebla, 72570, MEXICO.

In this work two high DFT correlation methodologies, the so called DFT+U (or GGA+U) implementation and the eece hybrid DFT functional (or one case of HYB-DFT), are tested to determine the mechanical properties of Americium-II. For each case, the numeric value of their principal parameter is chosen (U for the first case and α for the second one) once the crystalline structure meets all the mechanical stability conditions. The results show that there is a range of values of U and α in which both methodologies generate a stable (experimentally correct) non-magnetic ground state, reaching approximately the same numeric value of the set of elastic constants of the cubic structure. Read More

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December 2018
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Effectiveness assessment of risk reduction measures at coastal areas using a decision support system: Findings from Emma storm.

Sci Total Environ 2018 Dec 1;657:124-135. Epub 2018 Dec 1.

CIMA/FCT, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal. Electronic address:

Storms impact coastal areas often causing damages and losses at occupied areas. On a scenario of increasing human occupation at coastal zones and under climate change conditions (including sea level rise and increasing frequency of extreme sea levels), the consequences of storms are expected to be amplified if no adaptation or further management actions are implemented. The selection of the best possible coastal management measures, considering both costs and effectiveness, will be mandatory in the future, in order to optimise resources. Read More

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December 2018

Providing very preterm infants with donor human milk led to faster breastfeeding rates but worse biometric gains.

Acta Paediatr 2018 Dec 11. Epub 2018 Dec 11.

Department of Neonatology, Puerta de Hierro Majadahonda University Hospital, Madrid.

Aim: To evaluate the immediate clinical impact of donor human milk availability in a NICU about nutritional, clinical and biometric parameters.

Methods: This retrospective-cohort study included 28-32 weeks gestational age born at our hospital in a three-year period before and after the donor human milk implementation. Data about starting, advance and discharge enteral nutrition, clinical outcomes, hospital stay and biometrics, was collected. Read More

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December 2018

Understanding barriers to effective management of influenza outbreaks by residential aged care facilities.

Australas J Ageing 2018 Dec 10. Epub 2018 Dec 10.

Sydney Local Health District, Public Health Unit, Sydney, New South Wales, Australia.

Objective: To identify the perceived barriers to the implementation of the Australian national guidelines on influenza outbreak management with Sydney Local Health District (SLHD) residential aged care facility (RACF) staff.

Methods: All SLHD RACFs were invited to participate in a telephone interview. The questionnaire collected information about demographic characteristics and participants' level of agreement with statements regarding perceived barriers to implementing the national guidelines for influenza outbreak management. Read More

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December 2018

First Nations students' perceptions of school nutrition policy implementation: A mixed methods study.

Nutr Diet 2018 Nov;75(5):533-540

Department of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.

Aim: School nutrition policies can improve healthy food access for Indigenous First Nations children in Canada. This study explored First Nations students' perceptions of a school nutrition policy.

Methods: The research was a process evaluation of school nutrition policy implementation using a mixed-methods design. Read More

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November 2018

Trial Versus No Trial of Spinal Cord Stimulation for Chronic Neuropathic Pain: Cost Analysis in United Kingdom National Health Service.

Neuromodulation 2018 Dec 10. Epub 2018 Dec 10.

Basildon and Thurrock University Hospitals, Basildon, UK.

Objectives: The aim of the current project was to evaluate the spinal cord stimulation (SCS) screening trial success rate threshold to obtain the same cost impact across two identical sets of patients following either a prolonged screening trial prior to implantation strategy or a full implant without a screening trial.

Materials And Methods: A cost impact analysis was carried out from a health care perspective and considered trial to implant rates reported in the literature. Items of resource use were costed using national averages obtained from the National Health Service (NHS) reference cost data base. Read More

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December 2018

Facilitators and barriers to the implementation of motivational interviewing for bullying perpetration in school settings.

Scand J Psychol 2018 Dec 11. Epub 2018 Dec 11.

University of Western Australia - Telethon Kids Institute, Nedlands, Australia.

Bullying is a perplexing and persistent problem with negative consequences for all involved. Schools are assigned considerable responsibility for the management of bullying because of its prevalence amongst youth. Despite considerable efforts over decades to curtail bullying through the use of anti-bullying policies and other school-based interventions, the rates of young people who frequently bully has not decreased significantly. Read More

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December 2018

Iron-fortified formula use in young children and association with socioeconomic factors in the French nationwide ELFE cohort.

Acta Paediatr 2018 Dec 7. Epub 2018 Dec 7.

Inserm, UMR1153, Centre de Recherche en Épidémiologie et Statistique Sorbonne Paris Cité (CRESS), équipe Épidémiologie Périnatale, Obstétricale et Pédiatrique (ÉPOPé) Labex GR-Ex, Paris, France.

Sacri A-S, de Lauzon-Guillain B, Dufourg M-D, Bois C, Charles M A, Chalumeau M. Iron-fortified formula use in young children and association with socioeconomic factors in the French nationwide ELFE cohort.

Aim: To study the rate of iron-fortified infant formula (IFF) use in young children in France and its association with socioeconomic factors. Read More

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December 2018

Sowing social inclusion for marginalised residents of a social housing development through a community garden.

Health Promot J Austr 2018 Dec 7. Epub 2018 Dec 7.

School of Health and Social Development, Faculty of Health, Deakin University, Geelong, Australia.

Aim: In addition to food, physical activity, mental health and environmental benefits, community gardens (CGs) provide opportunities for social inclusion and increased social capital. These are particularly important to the socially isolated residents of Social Housing Developments (SHD). This scoping study explored the feasibility of a CG program for tenants of social housing development in inner eastern Melbourne by assessing their interest in, and requirements for, inclusively designed CGs. Read More

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December 2018
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How does 'Becoming Breastfeeding Friendly' work? A Program Impact Pathways analysis.

Matern Child Nutr 2018 Dec 7:e12766. Epub 2018 Dec 7.

Yale School of Public Health, New Haven, CT, USA.

Becoming Breastfeeding Friendly (BBF) is an initiative designed to track country readiness and progress to effectively scale up breastfeeding programs. BBF includes a policy toolbox that has three components: the Becoming Breastfeeding Friendly Index (BBFI), case studies, and a 5-meeting process. Mapping pathways of how BBF was implemented and utilized enables contextually grounded interpretation of its impact on breastfeeding outcomes. Read More

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December 2018
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Implementation of the transradial approach as an alternative vascular access for transcatheter aortic valve replacement guidance: Experience from a high-volume center.

Catheter Cardiovasc Interv 2018 Dec 10. Epub 2018 Dec 10.

Ramsay Générale de Santé, Institut Cardiovasculaire Paris Sud, Massy, Paris, France.

Objective: This study sought to assess the potential benefits of the transradial approach (TRA) as an alternative vascular access to the classical contralateral femoral approach for transcatheter aortic valve replacement (TAVR).

Background: Vascular and bleeding complications in TAVR have gradually decreased owing to operator experience and downsizing of the delivery system. However, about 1/4 of vascular access site complications are related to the transfemoral (TF) secondary access. Read More

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December 2018

Incidence of severe critical events in paediatric anaesthesia in the United Kingdom: secondary analysis of the anaesthesia practice in children observational trial (APRICOT study).

Anaesthesia 2018 Dec 10. Epub 2018 Dec 10.

Department of Paediatric Anaesthesia and Pain Management, University of Glasgow, Glasgow, Scotland, UK.

The anaesthesia practice in children observational trial of 31,127 patients in 261 European hospitals revealed a high (5.2%) incidence of severe critical events in the peri-operative period and wide variability in practice. A sub-analysis of the UK data was undertaken to investigate differences compared with the non-UK cohort in the incidence and nature of peri-operative severe critical events and to attempt to identify areas for quality improvement. Read More

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December 2018

District-level implementation of British Columbia's school food and beverage sales policy: a realist evaluation exploring intervention mechanisms in urban and rural contexts.

Can J Public Health 2018 Dec 7. Epub 2018 Dec 7.

Centre for Sustainable Food Systems, University of British Columbia, Vancouver, British Columbia, Canada.

Intervention: British Columbia's (BC) provincial school food and beverage sales policy.

Research Question: What are the processes associated with district-level implementation of BC's school food and beverage sales policy?

Methods: We adopted a realist approach and a qualitative, multiple case study design that included three urban and two rural BC school districts. Data collection involved semi-structured interviews and questionnaires with health, education, and industry stakeholders, observations, document analysis and website scans. Read More

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December 2018
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The Role of Culture of Origin on the Effectiveness of a Parents-Involved Intervention to Prevent Substance Use Among Latino Middle School Youth: Results of a Cluster Randomized Controlled Trial.

Prev Sci 2018 Dec 8. Epub 2018 Dec 8.

Global Center for Applied Health Research (GCAHR), Arizona State University, Phoenix, AZ, USA.

The purpose of this study was to assess the combined effectiveness of a parenting intervention, Families Preparing the New Generation (FPNG), and a youth curriculum, keepin' it REAL (kiR), on substance use prevention for middle school students in a large urban metro area of the southwest USA. The study aimed to generate usable knowledge on what works in adolescent substance use prevention and how it works best-a combined parent and youth programming or parent-only programming. A total of 532 adolescents in the 7th grade from 19 participating middle schools were randomly assigned into three intervention conditions: parent-youth (PY), parent-only (PO), and comparison (C). Read More

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December 2018

The Use of Molecular Oxygen for Liquid Phase Aerobic Oxidations in Continuous Flow.

Top Curr Chem (Cham) 2018 Dec 11;377(1). Epub 2018 Dec 11.

Center for Continuous Synthesis and Processing (CCFLOW), Research Center Pharmaceutical Engineering (RCPE), Inffeldgasse 13, 8010, Graz, Austria.

Molecular oxygen (O) is the ultimate "green" oxidant for organic synthesis. There has been recent intensive research within the synthetic community to develop new selective liquid phase aerobic oxidation methodologies as a response to the necessity to reduce the environmental impact of chemical synthesis and manufacture. Green and sustainable chemical processes rely not only on effective chemistry but also on the implementation of reactor technologies that enhance reaction performance and overall safety. Read More

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December 2018

A new one-step multiplex PCR assay for simultaneous detection and identification of avian haemosporidian parasites.

Parasitol Res 2018 Dec 7. Epub 2018 Dec 7.

Molecular Ecology and Evolution Laboratory, Department of Biology, Lund University, SE-223 62, Lund, Sweden.

Accurate detection and identification are essential components for epidemiological, ecological, and evolutionary surveys of avian haemosporidian parasites. Microscopy has been used for more than 100 years to detect and identify these parasites; however, this technique requires considerable training and high-level expertise. Several PCR methods with highly sensitive and specific detection capabilities have now been developed in addition to microscopic examination. Read More

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December 2018

Examining comprehensive cancer control partnerships, plans, and program interventions: successes and lessons learned from a utilization-focused evaluation.

Cancer Causes Control 2018 Dec 8. Epub 2018 Dec 8.

Comprehensive Cancer Control Branch, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA.

The National Comprehensive Cancer Control Program has experienced exponential growth over the past 20 years due to the coordination and collaboration of many stakeholders to sustain multisector coalitions, develop and execute data-driven plans, and successfully implement evidenced-based interventions across the United States. These stakeholders have worked tirelessly to address the burden of cancer by employing strategies that promote healthy behaviors to reduce cancer risk, facilitate screening, and address the needs of cancer survivors. The interaction between the comprehensive cancer control program and the coalitions to engage in this work has been coined the 3Ps: the partnership, the CCC plan, and CCC program interventions. Read More

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December 2018

Evaluating centralized technical assistance as an implementation strategy to improve cancer prevention and control.

Cancer Causes Control 2018 Dec 7. Epub 2018 Dec 7.

Prevention Research Center, Brown School, Washington University in St. Louis, One Brookings Drive, Campus, Box 1196, St. Louis, MO, 63130, USA.

Purpose: In 2015-2016, the Comprehensive Cancer Control National Partnership provided technical assistance workshops to support 22 cancer coalitions in increasing human papillomavirus (HPV) vaccination uptake and increasing colorectal cancer (CRC) screening in their local communities. As national efforts continue to invest in providing technical assistance, there is a current gap in understanding its use as a strategy to accelerate implementation of evidence-based interventions (EBIs) for cancer prevention. The objective of this study was to evaluate the impact of technical assistance on the participants' knowledge, attitudes, and skills for implementing EBIs in their local context and enhancing state team collaboration. Read More

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December 2018

Approaches to Deprescribing Psychotropic Medications for Changed Behaviours in Long-Term Care Residents Living with Dementia.

Drugs Aging 2018 Dec 11. Epub 2018 Dec 11.

Dementia Centre for Research Collaboration, School of Psychiatry, UNSW Sydney, Sydney, NSW, Australia.

Psychotropic medications have a high risk of serious adverse events and small effect size for changed behaviours for people with dementia. Non-pharmacological approaches are recommended as first-line treatment for changed behaviours, yet psychotropic medications remain highly prevalent in long-term aged care settings. This narrative review describes the current evidence regarding deprescribing psychotropic medications for people with dementia in long-term care. Read More

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December 2018

"Creative Financing": Funding Evidence-Based Interventions in Human Service Systems.

J Behav Health Serv Res 2018 Dec 10. Epub 2018 Dec 10.

Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive (8012), La Jolla, CA, 92093-0812, USA.

Implementation and sustainment of evidence-based interventions (EBIs) is influenced by outer (e.g., broader environments in which organizations operate) and inner (e. Read More

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December 2018

Implementation of CT-P13 via a Managed Switch Programme in Crohn's Disease: 12-Month Real-World Outcomes.

Dig Dis Sci 2018 Dec 7. Epub 2018 Dec 7.

The Edinburgh IBD Unit, Western General Hospital, Edinburgh, EH4 2XU, UK.

Background: Switching from Remicade to CT-P13 allows for significant cost savings and has been shown to be non-inferior to continued therapy with Remicade for the treatment of Crohn's disease.

Aim: The aim of this work was to prospectively evaluate clinical outcomes in a cohort of patients with Crohn's disease switching from Remicade to CT-P13.

Methods: A prospective service evaluation was performed. Read More

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December 2018

Implementation of a semiautomatic method to design patient-specific instruments for corrective osteotomy of the radius.

Int J Comput Assist Radiol Surg 2018 Dec 10. Epub 2018 Dec 10.

Amsterdam UMC, Department of Biomedical Engineering and Physics, University of Amsterdam, Amsterdam Movement Sciences, 1105 AZ, Amsterdam, The Netherlands.

Purpose: 3D-printed patient-specific instruments (PSIs), such as surgical guides and implants, show great promise for accurate navigation in surgical correction of post-traumatic deformities of the distal radius. However, existing costs of computer-aided design and manufacturing process prevent everyday surgical use. In this paper, we propose an innovative semiautomatic methodology to streamline the PSIs design. Read More

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December 2018

Perspectives on a Stage-Based Treatment for Posttraumatic Stress Disorder Among Dialectical Behavior Therapy Consumers in Public Mental Health Settings.

Community Ment Health J 2018 Dec 7. Epub 2018 Dec 7.

Department of Psychology, University of Washington, Box 351635, Seattle, WA, 98195, USA.

Difficulties with consumer engagement are a common barrier to implementing trauma-focused evidence-based psychotherapies (TF-EBPs). Potential methods of increasing engagement include utilizing a stage-based treatment approach, and involving consumers in implementation efforts. This mixed method study explored consumers' perspectives on a stage-based TF-EBP, Dialectical Behavior Therapy (DBT) with the DBT Prolonged Exposure (DBT PE) protocol. Read More

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December 2018

Communication and comprehensive cancer control coalitions: lessons from two decades of campaigns, outreach, and training.

Cancer Causes Control 2018 Dec 10. Epub 2018 Dec 10.

Department of Kinesiology and Health Education, The University of Texas at Austin, 2109 San Jacinto Blvd. (D3700), Austin, TX, 78712-1415, USA.

Purpose: Comprehensive cancer control (CCC) coalitions and programs have delivered effective models and approaches to reducing cancer burden across the United States over the last two decades. Communication plays an essential role in diverse coalition activities from prevention to survivorship, including organizational and community capacity-building and as cancer control intervention strategies.

Methods: Based upon a review of published CCC research as well as public health communication best practices, this article describes lessons learned to assist CCC coalitions and programs with systematic implementation of communication efforts as key strategies in cancer control. Read More

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December 2018
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Metabolomic-Based Methods in Diagnosis and Monitoring Infection Progression.

Exp Suppl 2018 ;109:283-315

Center for Metabolomics and Bioanalysis (CEMBIO), CEU San Pablo University, Boadilla del Monte, Spain.

A robust biomarker screening and validation is crucial for overcoming the current limits in the clinical management of infectious diseases. In this chapter, a general workflow for metabolomics is summarized. Subsequently, an overview of the major contributions of this omics science to the field of biomarkers of infectious diseases is discussed. Read More

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January 2018

PhenoMeNal: Processing and analysis of Metabolomics data in the Cloud.

Gigascience 2018 Dec 7. Epub 2018 Dec 7.

Cheminformatics and Computational Metabolomics, Institute for Analytical Chemistry, Lessingstr. 8, 07743 Jena, Germany.

Background: Metabolomics is the comprehensive study of a multitude of small molecules to gain insight into an organism's metabolism. The research field is dynamic and expanding with applications across biomedical, biotechnological and many other applied biological domains. Its computationally-intensive nature has driven requirements for open data formats, data repositories and data analysis tools. Read More

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December 2018
2 Reads

A glossary of user-centered design strategies for implementation experts.

Transl Behav Med 2018 Dec 7. Epub 2018 Dec 7.

Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.

User-centered design (UCD), a discipline that seeks to ground the design of an innovation in information about the people who will ultimately use that innovation, has great potential to improve the translation of evidence-based practices from behavioral medicine research for implementation in health care settings. UCD is a diverse, innovative field that remains highly variable in terms of language and approaches. Ultimately, we produced a glossary of UCD-related strategies specifically for experts in implementation research and practice, with the goal of promoting interdisciplinary collaboration in implementation efforts. Read More

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December 2018

Quality Improvement in Transfusion Practice of Orthotopic Liver Transplantation Reduces Blood Utilization, Length of Hospital Stay, and Cost.

Am J Clin Pathol 2018 Dec 8. Epub 2018 Dec 8.

Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN.

Objectives: Orthotopic liver transplantation (OLT) can require substantial usage of blood products. Higher rates of transfusion have been associated with increased length of hospital stay, higher rates of infection, graft failure, and mortality. This study was a retrospective analysis to assess the impact of quality improvement interventions in OLT. Read More

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December 2018

Prot-SpaM: Fast alignment-free phylogeny reconstruction based on whole-proteome sequences.

Gigascience 2018 Dec 7. Epub 2018 Dec 7.

University of Göttingen, Department of Bioinformatics, Goldschmidtstr. 1, 37077 Göttingen, Germany.

Word-based or 'alignment-free' sequence comparison has become an active research area in bioinformatics. While previous word-frequency approaches calculated rough measures of sequence similarity or dissimilarity, some new alignment-free methods are able to accurately estimate phylogenetic distances between genomic sequences. One of these approaches is Filtered Spaced Word Matches. Read More

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December 2018

Evaluation of methods for generative modeling of cell and nuclear shape.

Bioinformatics 2018 Dec 7. Epub 2018 Dec 7.

Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, USA.

Motivation: Cell shape provides both a geometry for, and a reflection of, cell function. Numerous methods for describing and modeling cell shape have been described, but previous evaluation of these methods in terms of the accuracy of generative models has been limited.

Results: Here we compare traditional methods and deep autoencoders to build generative models for cell shapes in terms of the accuracy with which shapes can be reconstructed from models. Read More

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December 2018

Database of evidence for precision oncology portal.

Bioinformatics 2018 Dec;34(24):4315-4317

Division of Oncology, School of Medicine, St. Louis, MO, USA.

Summary: A database of curated genomic variants with clinically supported drug therapies and other oncological annotations is described. The accompanying web portal provides a search engine with two modes: one that allows users to query gene, cancer type, variant type or position for druggable mutations, and another to search for and to visualize, on three-dimensional protein structures, putative druggable sites that cluster with known druggable mutations.

Availability And Implementation: http://dinglab. Read More

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December 2018

PopViz: a webserver for visualizing minor allele frequencies and damage prediction scores of human genetic variations.

Bioinformatics 2018 Dec;34(24):4307-4309

The Charles Bronfman Institute for Personalized Medicine.

Summary: Next-generation sequencing (NGS) generates large amounts of genomic data and reveals about 20 000 genetic coding variants per individual studied. Several mutation damage prediction scores are available to prioritize variants, but there is currently no application to help investigators to determine the relevance of the candidate genes and variants quickly and visually from population genetics data and deleteriousness scores. Here, we present PopViz, a user-friendly, rapid, interactive, mobile-compatible webserver providing a gene-centric visualization of the variants of any human gene, with (i) population-specific minor allele frequencies from the gnomAD population genetic database; (ii) mutation damage prediction scores from CADD, EIGEN and LINSIGHT and (iii) amino-acid positions and protein domains. Read More

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December 2018
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pyseer: a comprehensive tool for microbial pangenome-wide association studies.

Bioinformatics 2018 Dec;34(24):4310-4312

Department of Parasites and Microbes, Wellcome Sanger Institute, Hinxton, UK.

Summary: Genome-wide association studies (GWAS) in microbes have different challenges to GWAS in eukaryotes. These have been addressed by a number of different methods. pyseer brings these techniques together in one package tailored to microbial GWAS, allows greater flexibility of the input data used, and adds new methods to interpret the association results. Read More

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December 2018

MapOptics: A light-weight, cross-platform visualisation tool for optical mapping alignment.

Bioinformatics 2018 Dec 7. Epub 2018 Dec 7.

The Bioinformatics Group, School of Water, Energy and Environment, Cranfield University, College Road, Bedford, UK.

Summary: Bionano optical mapping is a technology that can assist in the final stages of genome assembly by lengthening and ordering scaffolds in a draft assembly by aligning the assembly to a genomic map. However, currently, tools for visualisation are limited to use on a Windows operating system or are developed initially for visualising large-scale structural variation. MapOptics is a lightweight cross-platform tool that enables the user to visualise and interact with the alignment of Bionano optical mapping data and can be used for in depth exploration of hybrid scaffolding alignments. Read More

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December 2018
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Practical generic guidelines for paediatric-to-adult transition for adolescents with chronic disease.

Eur J Public Health 2018 Dec 6. Epub 2018 Dec 6.

Unité ECEVE UMR 1123, Université Paris Diderot-Sorbonne Paris Cité, INSERM, Paris, France.

Background: The last 20 years have seen many attempts to improve transition to adult healthcare for adolescents with chronic disease, but there is currently no established consensus on generic practices. Our goal was to identify relevant and pragmatic guidelines for transition practice for each step of this process (before, during and after transfer), applicable to a wide range of chronic illnesses and health services, via a participatory approach involving all the key stakeholders.

Methods: We conducted interviews and a literature review to elaborate a questionnaire for use in an online 2-round Delphi survey. Read More

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December 2018

WIlsON: Web-based Interactive Omics VisualizatioN.

Bioinformatics 2018 Aug 23. Epub 2018 Aug 23.

Max Planck Institute for Heart and Lung Research, Bioinformatics Core Unit (BCU), Bad Nauheim, Germany.

Motivation: High throughput (HT) screens in the omics field are typically analyzed by automated pipelines that generate static visualizations and comprehensive spreadsheet data for scientists. However, exploratory and hypothesis driven data analysis are key aspects of the understanding of biological systems, both generating extensive need for customized and dynamic visualization.

Results: Here we describe WIlsON, an interactive workbench for analysis and visualization of multi-omics data. Read More

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August 2018
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Management of comorbid mental and somatic disorders in stepped care approaches in primary care: a systematic review.

Fam Pract 2018 Dec 7. Epub 2018 Dec 7.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Germany.

Background: Stepped care models comprise a graded treatment intensity and a systematic monitoring. For an effective implementation, stepped care models have to account for the high rates of mental and somatic comorbidity in primary care.

Objectives: The aim of the systematic review was to take stock of whether present stepped care models take comorbidities into consideration. Read More

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December 2018

[Implementation science to evaluate health programs and services].

Rev Med Chil 2018 Jul;146(7):945-946

Facultad de Medicina, Universidad San Sebastián, Chile.

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Correlations on the protection of personal data and intellectual property rights in medical research.

Rom J Morphol Embryol 2018 ;59(3):1001-1005

Department of Intellectual Property Law, Law School, University of Craiova, Romania;

Purpose: International regulations regarding the protection of individuals concerning the processing of personal data and the free movement of such data highlight the need for their systematization and customization, depending on the purpose for which they are collected and used.

Background: Medical legislation is structured so that the constitutional right to healthcare is guaranteed and at the same time be protected by respecting the right to privacy with respect to identity, physiological state of the person and the way this, by health maneuvers, was restored. European Union (EU) legislation is more and more complex related to the patients' right and also to the General Data Protection Regulation (GDPR). Read More

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January 2018

RELACS nuclei barcoding enables high-throughput ChIP-seq.

Commun Biol 2018 5;1:214. Epub 2018 Dec 5.

Max Planck Institute of Immunobiology and Epigenetics, Stübeweg 51, 79108 Freiburg, Germany.

Chromatin immunoprecipitation followed by deep sequencing (ChIP-seq) is an invaluable tool for mapping chromatin-associated proteins. Current barcoding strategies aim to improve assay throughput and scalability but intense sample handling and lack of standardization over cell types, cell numbers and epitopes hinder wide-spread use in the field. Here, we present a barcoding method to enable high-throughput ChIP-seq using common molecular biology techniques. Read More

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December 2018
1 Read

First Ukrainian Growth References for Height, Weight, and Body Mass Index for Children and Adolescents Aged 7 to 18 Years.

Biomed Res Int 2018 11;2018:9203039. Epub 2018 Nov 11.

Medical Faculty, University of Rzeszów, Poland.

To date, growth centiles of children and adolescents have not been created in Ukraine. Therefore, the aim of this study was to construct reference growth charts for height, weight, and body mass index (BMI) of Ukrainian school-aged children and to compare them with World Health Organization references from 2007 for children's BMI. . Read More

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November 2018

Development of a Self-Determination Theory-Based Physical Activity Intervention for Aged Care Workers: Protocol for the Activity for Well-being Program.

Front Public Health 2018 26;6:341. Epub 2018 Nov 26.

Alliance for Research in Exercise, Nutrition and Activity (ARENA), School of Health Sciences, University of South Australia, Adelaide, SA, Australia.

Despite the well-established benefits of regular participation in physical activity, many Australians still fail to maintain sufficient levels. More self-determined types of motivation and more positive affect during activity have been found to be associated with the maintenance of physical activity behaviour over time. Need-supportive approaches to physical activity behaviour change have previously been shown to improve quality of motivation and psychological well-being. Read More

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November 2018
1 Read

The Impact of Social Pensions on Intergenerational Relationships: Comparative Evidence from China.

J Econ Ageing 2018 Nov 10;12:225-235. Epub 2017 Apr 10.

Central University of Finance and Economics.

China launched a new rural pension scheme (hereafter NRPS) for rural residents in 2009, now covering almost all counties with over 400 million people enrolled. This implementation of the largest social pension program in the world offers a unique setting for studying the economics of intergenerational relationships during development, given the rapidity of China's population aging, traditions of filial piety and co-residence, decreasing number of children, and dearth of formal social security, at a relatively low income level. We draw on rich household surveys from two provinces at distinct development stages - impoverished Guizhou and relatively well-off Shandong - to better understand heterogeneity in the impact of pension benefits. Read More

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November 2018

Validity of the South African Triage Scale in a rural district hospital.

Afr J Emerg Med 2018 Dec 26;8(4):145-149. Epub 2018 Jul 26.

Zithulele Hospital, Mqanduli 5080, Eastern Cape, South Africa.

Introduction: The implementation of a triage system is a vital step in improving the functioning and patient flow of the emergency centre in a rural district hospital. The South African Triage Scale (SATS) is a well validated and reliable tool used widely in South Africa and other low- and middle-income countries. This study aims to assess the validity of the SATS in a rural district hospital context. Read More

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December 2018

A Single-visit Approach Using Fillers and Incobotulinumtoxin A: Full Face Enhancement in Asian Patients.

Authors:
Yates Y Y Chao

Plast Reconstr Surg Glob Open 2018 Oct 2;6(10):e1909. Epub 2018 Oct 2.

CHAO Institute of Aesthetic Medicine, Taipei, Taiwan.

A 3-dimensional, multi-layered approach combining modalities targeting different manifestations is recommended for achieving optimal esthetic outcomes. To date, studies reporting same-day treatment with dermal fillers and botulinum toxin have not been published. This article documents the practical use of a single-visit, pan-facial multimodal approach in addressing the varying esthetic needs of 8 Asian adults. Read More

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October 2018

Simulation-based training in urology residency programmes in the USA: Results of a nationwide survey.

Arab J Urol 2018 Dec 17;16(4):446-452. Epub 2018 Jul 17.

WWAMI Institute for Simulation in Healthcare (WISH), Department of Surgery, University of Washington, Seattle, WA, USA.

Objective: To evaluate the current usage of simulation in urological education in the USA and the barriers to incorporating a simulation-based educational curriculum, as the shift towards competency-based medical education has necessitated the introduction of simulation for training and assessing both non-technical and technical skills.

Materials And Methods: Residency programme directors at Accreditation Council for Graduate Medical Education (ACGME)-accredited urology training programmes in the USA were invited to respond to an anonymous electronic survey. The study evaluated the programme directors' experiences and opinions for the current usage of existing urology simulators. Read More

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December 2018

Preceptorship during health personnel students' clinical studies in nursing homes-An institutional perspective on an intervention.

Nurs Open 2019 Jan 14;6(1):144-154. Epub 2018 Sep 14.

Department of Public Health and Nursing, Faculty of Medicine and Health Sciences Norwegian University of Technology and Science Trondheim Norway.

Aim: The recruitment and retention of preceptors to mentor health professional students and apprentices in their clinical studies are not easy. The aim of this study was to investigate factors that hindered the implementation of an intervention intended to improve the working conditions for preceptors in nursing homes. The preceptorship was related to clinical studies for health professional students and apprentices. Read More

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January 2019

Discourse analysis of health providers' experiences using service design.

Nurs Open 2019 Jan 21;6(1):84-92. Epub 2018 Aug 21.

Molde University College Specialised University in Logistics Molde Norway.

Background: Municipal healthcare organizations are facing increasing challenges to developing more cost-effective organizations and services, particularly in nursing homes. The background for this article is an attempt in this concern; implementing service design in a nursing home.

Aim: The aim of the study is to explore nurses and nurse assistants' experiences using service design in a nursing home. Read More

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January 2019

Methicillin-resistant tracking spread among health-care workers and hospitalized patients in critical wards at a university hospital, Tehran, Iran.

New Microbes New Infect 2019 Jan 16;27:29-35. Epub 2018 Nov 16.

Department of Pathobiology, School of Public Health and Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Health-care workers may serve as a reservoir for dissemination of methicillin-resistant (MRSA) to patients in hospital settings. The present study aimed to screen MRSA in nasal swabs of health-care workers and clinical specimens from patients and investigate the possible relationship between these isolates at a university hospital in Tehran, Iran. Additionally, we aimed to identify potential risk factors for MRSA colonization in health-care workers. Read More

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January 2019

Potential strategies for sustainably financing mental health care in Uganda.

Int J Ment Health Syst 2018 5;12:74. Epub 2018 Dec 5.

Butabika National Referral and Teaching Mental Hospital, Kampala, Uganda.

Background: In spite of the pronounced adverse economic consequences of mental, neurological, and substance use disorders on households in most low- and middle-income countries, service coverage and financial protection for these families is very limited. The aim of this study was to generate potential strategies for sustainably financing mental health care in Uganda in an effort to move towards increased financial protection and service coverage for these families.

Methods: The process of identifying potential strategies for sustainably financing mental health care in Uganda was guided by an analytical framework developed by the Emerging Mental health systems in low and middle income countries (EMERALD project). Read More

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December 2018