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Front Syst Neurosci 2018 1;12:73. Epub 2019 Feb 1.

Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, United States.

Despite appearing automatic and effortless, perceiving the visual world is a highly complex process that depends on intact visual and oculomotor function. Understanding the mechanisms underlying spatial updating (i.e. Read More

BMC Ear Nose Throat Disord 2019 4;19. Epub 2019 Feb 4.

1Service d'Oto-Rhino-Laryngologie, d'Oto-Neurologie et d'ORL Pédiatrique, Centre Hospitalier Universitaire de Toulouse, Place du Dr Baylac, 31059 Toulouse Cedex 9, France.

Background: Single-sided deafness (SSD) and asymmetric hearing loss (AHL) have recently been proposed as a new indication for cochlear implantation. There is still no recommended treatment for these hearing deficits, and most options considered rely on the transfer of sound from the poor ear to the better ear, using Contralateral Routing of the Signal (CROS) hearing aids or bone conduction (BC) devices. In contrast, cochlear implantation allows the poor ear to be stimulated and binaural hearing abilities to be partially restored. Read More

Sci Rep 2019 Feb 14;9(1):2091. Epub 2019 Feb 14.

Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.

Fibrin glue has been used clinically for decades in a wide variety of surgical specialties and is now being investigated as a medium for local, prolonged drug delivery. Effective local delivery of antibacterial substances is important perioperatively in patients with implanted medical devices or postoperatively for deep wounds. However, prolonged local application of antibiotics is often not possible or simply inadequate. Read More

Sci Rep 2019 Feb 14;9(1):2124. Epub 2019 Feb 14.

Physical Sciences Platform, Sunnybrook Health Sciences Institute, Toronto, Ontario, M4N 3M5, Canada.

Patients with deep brain stimulation (DBS) implants may be subject to heating during MRI due to interaction with excitatory radiofrequency (RF) fields. Parallel RF transmit (pTx) has been proposed to minimize such RF-induced heating in preliminary proof-of-concept studies. The present work evaluates the efficacy of pTx technique on realistic lead trajectories obtained from nine DBS patients. Read More

J Invasive Cardiol 2019 Feb 15. Epub 2019 Feb 15.

North Shore Hospital, 124 Shakespeare Rd, Takapuna, Auckland 0620, New Zealand.

Background: Calcified coronary lesions often cause suboptimal stent expansion, which is one of the greatest predictors of adverse outcomes such as stent thrombosis and restenosis. Shockwave intravascular lithotripsy (S-IVL; Shockwave Medical, Inc) is a recently approved technique used in the treatment of heavily calcified coronary lesions. We present our early real-world experience with the S-IVL device. Read More

Curr Heart Fail Rep 2019 Feb 14. Epub 2019 Feb 14.

Division of Cardiovascular Medicine, Wexner Medical Center at The Ohio State University, 473 W. 12th Avenue Suite 200, Columbus, OH, 43210, USA.

Purpose Of Review: Despite advances in medical therapy, heart failure with reduced ejection fraction (HFrEF) is still a leading cause of mortality, hospitalizations, and healthcare costs. In this review, we describe two novel, implantable devices for the treatment of patients with HFrEF, cardiac contractility modulation (CCM), and baroreflex activation therapy (BAT), and summarize literature regarding these devices from the last 5 years.

Recent Findings: CCM improves quality of life and functional capacity as assessed by the Minnesota Living with Heart Failure Questionnaire (MLHFQ) score, 6-min hall walk test (6MHWT) distance, New York Heart Association (NYHA) functional class, peak oxygen consumption (pVO), heart failure (HF) hospitalizations, and mortality. Read More

J Endovasc Ther 2019 Feb 24;26(1):113-120. Epub 2018 Dec 24.

3 Department of Surgery (Division of Vascular Surgery), Medisch Spectrum Twente, Enschede, the Netherlands.

Purpose: To evaluate the incidence and treatment of limb occlusions of the second- and third-generation Anaconda endografts.

Methods: A single-center retrospective study was conducted involving 317 consecutive patients (mean age 76 years; 289 men) who underwent endovascular aneurysm repair for elective asymptomatic, symptomatic intact, and ruptured infrarenal abdominal aortic aneurysm with 2 versions of the Anaconda device. From September 2003 to July 2011, the second-generation device was used in 189 patients (mean age 77 years; 169 men) and from July 2011 to September 2015, the third-generation device was implanted in 128 patients (mean age 75 years; 120 men). Read More

Clin Res Cardiol 2019 Feb 13. Epub 2019 Feb 13.

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.

Background: Atrial high rate episodes (AHREs) detected by cardiac implantable electronic devices (CIEDs) are associated with an increased risk of stroke. However, the impact of AHRE on improving stroke risk stratification scheme remains uncertain.

Objective: The purpose of this study was to assess the impact of AHRE on prognosis in relation with cardiovascular events and risk stratification. Read More

J Am Heart Assoc 2019 Feb;8(4):e010661

1 Clinical and Translational Neuroscience Unit Feil Family Brain and Mind Research Institute Weill Cornell Medical College New York NY.

Background Black individuals in the United States experience higher rates of ischemic stroke than other racial groups but have lower rates of clinically apparent atrial fibrillation ( AF ). It is unclear whether blacks truly have less AF or simply more undiagnosed AF . Methods and Results We performed a retrospective cohort study using inpatient and outpatient claims from 2009 to 2015 for a 5% nationally representative sample of Medicare beneficiaries. Read More

Pacing Clin Electrophysiol 2019 Feb 10. Epub 2019 Feb 10.

Department of Cardiology, Centre for Heart Disease, 4th Military Hospital, Wroclaw, Poland.

Background: Seat belt use is the single most effective means of reducing fatal injuries in road traffic accidents. The presence of cardiac implantable electronic device (CIED) might influence seat belt-related behaviours due to the physical proximity of the seat belt and left subclavian area in which the device is usually implanted. Understanding the underlying mechanisms of improper seat belt use may improve safety of these patients. Read More

F1000Res 2019 25;8. Epub 2019 Jan 25.

Men's Health Center, Indianapolis, Indiana, USA.

Erectile dysfunction (ED) is important to a man's well-being and health, since it not only affects the individual but also causes strain on a couple's lifestyle and relationship. There are multiple non-invasive treatments that exist for ED including lifestyle changes, oral medications (phosphodiesterase type 5 inhibitors), vacuum-assisted erectile devices, and intraurethral suppositories. While lifestyle changes and oral medications are typically first-line treatments for ED, more-invasive treatments including intracavernosal injections and surgically implanted prosthetic devices may be required for the management of complex cases. Read More

J Electrocardiol 2019 Jan 25;53:100-108. Epub 2019 Jan 25.

Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.

Aims: Remote monitoring by implantable devices substantially improves management of heart failure (HF) patients by providing diagnostic day-to-day data. The use of thoracic impedance (TI) as a surrogate measure of fluid accumulation is still strongly debated. The multicenter HomeCARE-II study evaluated clinically apparent HF events in the context of remote device diagnostics, focusing on the controversial role of TI. Read More

Med Chem 2019 Feb 6. Epub 2019 Feb 6.

Depatment of Genetics, Maharshi Dayanand University, Rohtak-124001, Haryana. India.

Background: Staphylococus epidermidis coagulase negative and gram positive streptococci have emerge as major nosocomial pathogens associated with infection of implanted medical devices and dandruff in human scalp. S. epidermidis filamenting temperature-sensitive mutant Z (FtsZ) gene encoded FtsZ protein that assembles at future bacterial cell division site that form Z-ring structure. Read More

Toxicol Pathol 2019 Feb 5:192623319827502. Epub 2019 Feb 5.

1 Medtronic PLC, Physiological Research Laboratories, Minneapolis, Minnesota, USA.

Medical device pathologists are involved in the preclinical evaluation of medical devices that will be temporarily inserted or permanently and often irreversibly implanted in the human body. The medical device industry is technology based, allowing for rapid device iterations; innovations occur at an accelerated rate compared to the innovations in the pharmaceutical industry. The device pathologist provides the pathology results and is, by training and experience, in an ideal position to help the medical engineer and innovator tackle biomedical problems and to comment on the possible and actual outcomes of preclinical studies. Read More

Biosens Bioelectron 2019 Mar 22;129:198-207. Epub 2019 Jan 22.

University Hospital Tübingen, Section Medical Materials Science & Technology, Osianderstr. 2-8, D-72076 Tübingen, Germany. Electronic address:

Bacteria adhering to implanted medical devices can cause invasive microbial infections, of e.g. skin, lung or blood. Read More

Ann Surg 2019 Feb 1. Epub 2019 Feb 1.

Division of Cardiac, Thoracic, and Vascular Surgery, New York-Presbyterian/Columbia University Irving Medical Center/Columbia University Vagelos College of Physicians and Surgeons, New York, NY.

Objective: To compare outcomes of fenestrated (FEVAR) and open repairs of complex abdominal aortic aneurysms (cAAA).

Background: FEVAR has emerged as an alternative to open surgery for treating cAAA, but direct comparisons are limited.

Methods: We studied all repairs of intact or symptomatic cAAA in the Vascular Quality Initiative between 2012 and 2018, excluding chimney/snorkels and any devices implanted under Investigational Device Exemption studies. Read More

Kardiologiia 2019 Jan 26;59(1):5-11. Epub 2019 Jan 26.

Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science.

Purpose: to assess the association between depression and all-cause mortality in patients with congestive heart failure (CHF) after cardiac resynchronization therapy (CRT).

Materials And Methods: We enrolled in this study 156 patients (mean age 55.3±9. Read More

J Biomed Mater Res A 2019 Jan 31. Epub 2019 Jan 31.

Key laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, 226001, Nantong, P.R. China.

The effective repair and functional recovery after peripheral nerve injury is still a hot topic in clinical research. The aim of this study was to construct a bioactive composite hydrogel conduit as a three-dimensional scaffold for the repair of rat sciatic nerve defects. The composite hydrogel conduit was fabricated by blending different volumes of polyacrylamide, graphene oxide, gelatin and sodium alginate(PAM/GO/Gel/SA，PGGS) and injecting into a self-made mold with an inner diameter of 2 mm and an outer diameter of 6 mm. Read More

Sensors (Basel) 2019 Jan 28;19(3). Epub 2019 Jan 28.

Department of Health Science and Technology, GAIHST, Incheon 21999, Korea.

This paper presents a fully integrated photodiode-based low-power and low-mismatch stimulator for a subretinal prosthesis. It is known that a subretinal prosthesis achieves 1600-pixel stimulators on a limited single-chip area that is implanted beneath the bipolar cell layer. However, the high-density pixels cause high power dissipation during stimulation and high fabrication costs because of special process technologies such as the complementary metal-oxide semiconductor CMOS image sensor process. Read More

Sci Rep 2019 Jan 28;9(1):810. Epub 2019 Jan 28.

Department of Bioengineering, University of California, Riverside, CA, 92521, USA.

Magnesium (Mg) and its alloys have shown attractive biocompatibility and mechanical strength for medical applications, but low corrosion resistance of Mg in physiological environment limits its broad clinical translation. Hydroxyapatite (HA) nanoparticles (nHA) are promising coating materials for decreasing degradation rates and prolonging mechanical strength of Mg-based implants while enhancing bone healing due to their osteoconductivity and osteoinductivity. Conformal HA coatings with nano-to-submicron structures, namely nHA and mHA coatings, were deposited successfully on Mg plates and rods using a transonic particle acceleration (TPA) process under two different conditions, characterized, and investigated for their effects on Mg degradation in vitro. Read More

J Heart Lung Transplant 2019 Feb;38(2):114-126

Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.

Background: The Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs), a joint effort among the National Heart, Lung, and Blood Institute, the Food and Drug Administration, the Centers for Medicare and Medicaid Services, and others, was established in 2005 at the University of Alabama at Birmingham. The registry examined clinical outcomes and quality-of-life metrics of patients who received an Food and Drug Administration-approved durable mechanical circulatory support (MCS) device to treat advanced heart failure. On January 1, 2018, the Intermacs Database became part of The Society of Thoracic Surgeons National Database, providing additional resources for quality assessment and improvement and scientific advancement. Read More

Ann Thorac Surg 2019 Feb;107(2):341-353

Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.

Background: The Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs), a joint effort among the National Heart, Lung, and Blood Institute, the Food and Drug Administration, the Centers for Medicare and Medicaid Services, and others, was established in 2005 at the University of Alabama at Birmingham. The registry examined clinical outcomes and quality-of-life metrics of patients who received an Food and Drug Administration-approved durable mechanical circulatory support (MCS) device to treat advanced heart failure. On January 1, 2018, the Intermacs Database became part of The Society of Thoracic Surgeons National Database, providing additional resources for quality assessment and improvement and scientific advancement. Read More

ASAIO J 2019 Jan 24. Epub 2019 Jan 24.

From the Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.

We observed different temporal patterns of HeartMate II left ventricular assist device (LVAD) thrombosis regarding clinical manifestations and lactate dehydrogenase (LDH) trends. We propose nomenclature for classification of LVAD thrombosis and compare patient characteristics and outcomes in each pattern of LVAD thrombosis. We reviewed electronic medical records of 362 consecutive HeartMate II devices implanted at Cleveland Clinic from October 2008 to July 2014. Read More

Medicine (Baltimore) 2019 Jan;98(4):e14276

Department of Cardiology, Dalian Municipal Central Hospital affiliated of Dalian Medical University, Dalian, Liaoning, China.

The objective of this study is to investigate the sensitivity of contrast-enhanced transthoracic echocardiography (c-TTE) versus transesophageal echocardiography (TEE) to detect a residual right-to-left shunt (RLS) following a transcatheter patent foramen ovale (PFO) closure.A self-controlled study was conducted in a tertiary referral hospital. 57 patients with PFO who had experienced migraines underwent percutaneous PFO closure. Read More

J Cardiovasc Electrophysiol 2019 Jan 24. Epub 2019 Jan 24.

Cardioangiologisches Centrum Bethanien (CCB) Frankfurt am Main, Frankfurt Academy For Arrhythmias (FAFA), Medizinische Klinik III, Agaplesion Markus Krankenhaus, Frankfurt, Germany.

Introduction: Disturbance of sympathetic and vagal nervous system participates in the pathogenesis of hypertension and atrial fibrillation (AF). Renal denervation (RDN) can modulate autonomic nervous activity and reduce blood pressure (BP) in hypertensive patients. We aimed to evaluate the effect of RDN combined with pulmonary vein isolation (PVI) in patients with AF and hypertension. Read More

Mater Sci Eng C Mater Biol Appl 2019 Apr 19;97:864-883. Epub 2018 Dec 19.

Department of Astronautical Science and Mechanics, Harbin Institute of Technology (HIT), P.O. Box 301, No. 92 West Dazhi Street, Harbin 150001, People's Republic of China. Electronic address:

As a kind of intelligent material, shape memory polymer (SMP) can respond to outside stimuli and possesses good properties including shape memory effect, deformability and biological compatibility, etc. SMPs have been introduced for medical applications such as tissue engineering, biological sutures, stents and bladder sensors. Due to the shape memory effect, the medical devices based on SMP can be implanted into body through minimally invasive surgery in contraction or folded state and recovered to their requisite original shapes at target position. Read More

Nat Commun 2019 01 23;10(1):393. Epub 2019 Jan 23.

Department of Neuroscience, Washington University in St Louis, St Louis, MO, 63110, USA.

Previous work showed that economic decisions can be made independently of spatial contingencies. However, when goods available for choice bear different action costs, the decision necessarily reflects aspects of the action. One possibility is that "stimulus values" are combined with the corresponding action costs in a motor representation, and decisions are then made in actions space. Read More

Eur Radiol Exp 2019 Jan 22;3(1). Epub 2019 Jan 22.

Neurozentrum, Klinikum Stuttgart, Stuttgart, Germany.

Background: Flow-diverter stents (FDSs) have revolutionised the treatment of intracranial aneurysms. However, associated dual antiplatelet treatment is mandatory. We investigated the biocompatibility of three proprietary antithrombogenic coatings applied to FDSs. Read More

Antimicrob Agents Chemother 2019 Jan 22. Epub 2019 Jan 22.

State Key Laboratory of Ultrasound Engineering in Medicine Co-Founded by Chongqing and the Ministry of Science and Technology, Chongqing Collaborative Innovation Center for Minimally- invasive and Noninvasive Medicine, College of Biomedical Engineering, Chongqing Medical University, Chongqing 400016, China.

is a human opportunistic pathogen that causes superficial and life-threatening infections. An important reason for the failure of current antifungal drugs is related to biofilm formation, mostly associated with implanted medical devices. The present study investigated the synergistic antifungal efficacy of low-frequency and low-intensity ultrasound combined with amphotericin B-loaded PLGA nanoparticles (AmB-NPs) on biofilms. Read More

J Neurosci Methods 2019 Jan 18. Epub 2019 Jan 18.

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, United States; Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, United States. Electronic address:

Background: Brain-implanted devices, including intracortical microelectrodes, are used in neuroscience applications ranging from research to rehabilitation and beyond. Significant efforts are focused on developing new device designs and insertion strategies that mitigate initial trauma and subsequent neuroinflammation that occurs as a result of implantation. A frequently published metric is the neuroinflammatory response quantified as a function of distance from the interface edge, using fluorescent immunohistochemical markers. Read More

J Cardiovasc Electrophysiol 2019 Jan 19. Epub 2019 Jan 19.

Division of Cardiology, Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina.

Introduction: Leadless pacemakers may provide a safe and attractive pacing option to patients with cardiac implantable electronic device (CIED) infection. We describe the characteristics and outcomes of patients with a recent CIED infection undergoing Micra implant attempt.

Methods And Results: Patients with prior CIED infection and device explant with Micra implant within 30 days, were identified from the Micra post approval registry. Read More

Isr J Health Policy Res 2019 Jan 17;8(1):13. Epub 2019 Jan 17.

Goldschleger Eye Institute, Sheba Medical Center, Sackler Faulty of Medicine, Tel Aviv University, Tel Hashomer, Israel.

The Israel Ministry of Health enacted regulations that aim to reduce private expenditure on healthcare services and mitigate social inequality. According to the modified rules, which went into effect in the second half of 2016, patients who undergo surgery in a private hospital and are covered by their healthcare provider's supplemental insurance (SI) make only a basic co-payment.The modified regulations limited the option of self-payment for advanced devices not covered by national health basket, meaning that patients for whom such devices are indicated had to pay privately for the entire procedure. Read More

Medicine (Baltimore) 2019 Jan;98(3):e14169

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University.

We aimed to evaluate the safety and efficacy of combined airway and esophageal stents under fluoroscopy guidance and local anesthesia for patients with malignant tracheobronchial and esophageal disease. This retrospective analysis included 35 consecutive patients underwent combined stenting from March 2012 to August 2016. All patients underwent chest computed tomography scans before stenting and during follow-up. Read More

Medicine (Baltimore) 2019 Jan;98(3):e14097

Clinical Affairs Department, Zimmer Biomet Spine, Troyes, France.

Cervical cages with integrated fixation have been increasingly used in anterior cervical discectomy and fusion (ACDF) to avoid complications associated with anterior cervical plates. The purpose of this paper is to provide 2-year follow-up results of a prospective study after implantation of a cervical cage with an integrated fixation system.This was a prospective multicenter outcome study of 90 patients who underwent ACDF with a cage with integrated fixation. Read More

Eur Spine J 2019 Jan 16. Epub 2019 Jan 16.

Faculty of Medicine and University Hospital Cologne, Department of Orthopedics and Trauma Surgery, University of Cologne, Joseph-Stelzmann-Str. 24, 50931, Cologne, Germany.

Purpose: International Standards Organization (ISO) 12189 and American Society for Testing and Materials F2624 are two standard material specification and test methods for spinal implant devices. The aim of this study was to assess whether the existing and required tests before market launch are sufficient.

Methods: In three prospective studies, patients were treated due to degenerative disease of the lumbar spine or spondylolisthesis with lumbar interbody fusion and dynamic stabilization of the cranial adjacent level. Read More

Vet Comp Orthop Traumatol 2019 Jan 15;32(1):79-86. Epub 2019 Jan 15.

Sydney School of Veterinary Science, Faculty of Science, University of Sydney, Sydney, New South Wales, Australia.

Objectives:  The main purpose of this study was to design, manufacture and implant a customized three-dimensional (3D) printed, intervertebral spacer to treat disc-associated cervical spondylomyelopathy (DACSM) in dogs. This study also used advanced imaging to assess implant movement, subsidence and interbody fusion.

Animals:  Two client-owned dogs with DACSM. Read More

Nutr Clin Pract 2019 Jan 15. Epub 2019 Jan 15.

Center for Heart Transplant and Assist Devices, Advocate Christ Medical Center, Oak Lawn, Illinois, USA.

Background: Left ventricular assist device (LVAD) implantation for advanced heart failure is known to improve survival, functional capacity, and quality of life. Most patients implanted with LVADs suffer from moderate to severe malnutrition and deconditioning due to their advanced disease. The Mini Nutritional Assessment (MNA) and the short form of the survey (MNA-SF) are 2 well-validated clinical tools, previously used to assess patient nutrition status in numerous conditions. Read More

Nature 2019 01;565(7739):298-300

Sci Rep 2019 Jan 14;9(1):109. Epub 2019 Jan 14.

Auditory Prostheses and Perception Laboratory, Boys Town National Research Hospital, 555 N 30th Street, Omaha, NE, 68131, USA.

In tonal languages, voice pitch inflections change the meaning of words, such that the brain processes pitch not merely as an acoustic characterization of sound but as semantic information. In normally-hearing (NH) adults, this linguistic pressure on pitch appears to sharpen its neural encoding and can lead to perceptual benefits, depending on the task relevance, potentially generalizing outside of the speech domain. In children, however, linguistic systems are still malleable, meaning that their encoding of voice pitch information might not receive as much neural specialization but might generalize more easily to ecologically irrelevant pitch contours. Read More

G Ital Cardiol (Rome) 2019 Jan;20(1):32-40

Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza Università di Roma, Roma.

Leadless pacemaker therapy now represents a reality in the field of cardiac pacing. It was developed with the aim of reducing post-procedural complications due to endocavitary leads and with the intention to propose itself as a valid alternative in patients who have contraindications to conventional pacing. Leadless pacemakers to date allow right ventricular stimulation and are implanted through a percutaneous venous femoral access. Read More

Drug Alcohol Depend 2019 Feb 4;195:140-147. Epub 2019 Jan 4.

Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. Electronic address:

Background: 3,4-methylenedioxypyrovalerone (MDPV) toxicity includes intense neurological and cardiovascular events. We examined MDPV-induced cardiovascular, temperature, and locomotor effects following escalating and repeated MDPV administration in adult male and female Sprague-Dawley rats and compared these effects to cocaine in male rats.

Methods: Telemetry devices were surgically implanted to allow continuous measurement of cardiovascular, temperature, and locomotor activity over a 22 h period after dosing. Read More

J Biomed Mater Res B Appl Biomater 2019 Jan 10. Epub 2019 Jan 10.

Orthopaedic Research Laboratories, George E. Wahlen Department of Veterans Affairs Medical Center, and University of Utah Orthopaedic Center, Salt Lake City, Utah, 84148.

Negative Pressure Wound Therapy (NPWT) has been shown to limit downgrowth around percutaneous devices in a guinea pig model. However, the influence of NPWT on peri-prosthetic tissue characteristics leading to limited downgrowth is still unclear. In order to investigate this, 12 CD hairless rats were assigned into two groups, NPWT and Untreated (n = 6/group). Read More

Radiol Case Rep 2019 Mar 3;14(3):381-384. Epub 2019 Jan 3.

Department of Medicine, Pavlov First Saint Petersburg State Medical University, L'va Tolstogo str. 6-8, Saint-Petersburg, 197022, Russian Federation.

The recent increase in the number of patients with implanted peripherally inserted central catheters (PICCs) requires physicians to be familiar with rare and unusual complication-pinch-off syndrome (POS). We present a case of a 40-years-old female with human epidermal growth factor receptor type 2 (HER2)-positive breast cancer and implanted Groshong PICC (BARD). The patient was admitted for an elective chest and abdomen CT angiography control after finishing her trastuzumab and paclitaxel chemotherapy course a month earlier. Read More

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Jan 8;54(1):22-36. Epub 2019 Jan 8.

Sepsis and septic shock represent medical emergencies with persistently high mortality rates. According to the lately revised Surviving Sepsis Campaign (SSC) guidelines, focus identification/pathogen detection and the initial administration of broad-spectrum antibiotics are to be secluded within one hour after recognition of the symptoms of sepsis. However, there is dispute concerning the so called hour-1 bundle. Read More

Otolaryngol Clin North Am 2019 Jan 3. Epub 2019 Jan 3.

New York Otolaryngology Group, 36A East 36th Street, New York, NY 10016, USA.

A new category of hearing technology has emerged that comprises devices inserted deep into the ear canal. Although not implanted, they represent an extension of what is expected of a traditional hearing aid. There are advantages to these devices, but they are not suited for all individuals with hearing loss. Read More

J Interv Card Electrophysiol 2019 Jan 5. Epub 2019 Jan 5.

Cardiovascular Surgery Department, Military Medical Academy named after S.M. Kirov, Saint Petersburg, Russia.

Russia is the largest country in the world based on the landmass, covering more than one-eighth of the earth's inhabited area. Russia faces challenges in electrophysiology (EP) care including insufficient and uneven financing, complicated system for identifying optimal treatment for individual patients, relative paucity of reasonable educational and certification scope for electrophysiologists, suboptimal national statistical data gathering regarding heart rhythm disorders and EP devices in use, and weak networking of medical information. In comparison with the average level of EP utilization in ESC countries, Russia utilizes around 50% in pacemaker; 10% in ICD; 8% in cardiac resynchronization therapy; 55% in ablations; and 45% in AF ablations. Read More

Adv Healthc Mater 2019 Feb 4;8(3):e1801381. Epub 2019 Jan 4.

State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 199 Ren'ai Road, Suzhou, 215123, P. R. China.

Antibacterial coatings that eliminate initial bacterial attachment and prevent subsequent biofilm formation are essential in a number of applications, especially implanted medical devices. Although various approaches, including bacteria-repelling and bacteria-killing mechanisms, have been developed, none of them have been entirely successful due to their inherent drawbacks. In recent years, antibacterial coatings that are responsive to the bacterial microenvironment, that possess two or more killing mechanisms, or that have triggered-cleaning capability have emerged as promising solutions for bacterial infection and contamination problems. Read More

Bone Joint J 2019 Jan;101-B(1):47-54

Wrightington Hospital, Wigan, UK.

Aims: We report the long-term clinical and radiological outcomes of a consecutive series of 200 total ankle arthroplasties (TAAs, 184 patients) at a single centre using the Scandinavian Total Ankle Replacement (STAR) implants.

Patients And Methods: Between November 1993 and February 2000, 200 consecutive STAR prostheses were implanted in 184 patients by a single surgeon. Demographic and clinical data were collected prospectively and the last available status was recorded for further survival analysis. Read More

Int J Pediatr Otorhinolaryngol 2019 Mar 21;118:97-102. Epub 2018 Dec 21.

Institute of Physiology and Pathology of Hearing, World Hearing Center, Otorhinolaryngology Surgery Clinic, Mokra 17 Str., 05-830, Kajetany, Poland.

Introduction: For children with conductive or mixed hearing loss, in whom use of conventional hearing aids is impossible or limited, use of bone conduction devices is recommended. The choice between the available types of devices depends mostly on the degree of hearing loss, age, and anatomical conditions. One device application in children older than 5 years is the Bonebridge implant. Read More