16,510 results match your criteria Implantable Cardioverter-Defibrillators


International Triadin Knockout Syndrome Registry: The Clinical Phenotype and Treatment Outcomes of Patients with Triadin Knockout Syndrome.

Circ Genom Precis Med 2019 Jan 16. Epub 2019 Jan 16.

Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN.

Background: Triadin knockout syndrome (TKOS) is a rare, inherited arrhythmia syndrome caused by recessive null mutations in TRDN-encoded cardiac triadin. Based previously on five TRDN null patients, TKOS has been characterized by extensive T-wave inversions, transient QT prolongation, and severe disease expression of exercise-induced cardiac arrest in early childhood refractory to conventional therapy.

Methods: We have established the International Triadin Knockout Syndrome Registry (ITKOSR) to include patients who have genetically proven homozygous/compound heterozygous TRDN null mutations. Read More

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http://dx.doi.org/10.1161/CIRCGEN.118.002419DOI Listing
January 2019

Sex Differences in Acute Complications of Cardiac Implantable Electronic Devices: Implications for Patient Safety.

J Am Heart Assoc 2019 Jan;8(2):e010869

3 Health Performance & Policy Research Unit Basil Hetzel Institute for Translational Research Woodville South South Australia.

Background To date, limited population-level studies have examined the impact of sex on the acute complications of cardiac implantable electronic devices ( CIED) , including permanent pacemakers, implantable cardioverter defibrillators, and cardiac resynchronization therapy devices. Methods and Results We studied all patients aged >18 years from 2010 to 2015 who were a resident of Australia or New Zealand, undergoing a new permanent pacemaker, implantable cardioverter defibrillator, or cardiac resynchronization therapy implant. Standardized variables were collected including patient demographic characteristics, primary and secondary diagnoses, procedures performed and discharge status. Read More

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http://dx.doi.org/10.1161/JAHA.118.010869DOI Listing
January 2019

Clinical impact of cardiovascular magnetic resonance with optimized myocardial scar detection in patients with cardiac implantable devices.

Int J Cardiol 2019 Jan 4. Epub 2019 Jan 4.

Department of Cardiovascular Imaging, Barts Heart Centre, St Bartholomew's Hospital, London, UK; Institutes for Cardiovascular Science, University College London, London, UK. Electronic address:

Background: Myocardial scar assessment using late gadolinium enhancement Cardiovascular Magnetic Resonance (LGE CMR) is commonly indicated for patients with cardiac implantable electronic devices (CIEDs), however metal artifact can degrade images. We evaluated the clinical impact of LGE CMR incorporating a device-dependent metal artifact reduction strategy in patients with CIEDs.

Methods: 136 CMR studies were performed in 133 consecutive patients (age 56 ± 19 years, 69% male) with CIEDs (22% implantable loop recorders [ILRs], 40% permanent pacemakers [PPMs], 38% implantable cardioverter defibrillators [ICDs]; 42% non-MRI conditional) over 2 years, without complication. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.01.005DOI Listing
January 2019

The necessity of implantable cardioverter defibrillators in patients with Kearns-Sayre syndrome - systematic review of the articles.

Int J Cardiol 2018 Dec 27. Epub 2018 Dec 27.

Department of Pathophysiology, Oita University, 1397-1, Yamane, Hidaka, Saitama 350-1298, Japan.

The most common cardiac feature of Kearns-Sayre syndrome (KSS) is atrioventricular block (AVB), and pacemaker implantations (PMIs) are recommended for KSS patients with advanced AVB. However, some KSS patients develop fatal arrhythmias such as polymorphic ventricular tachycardia (PMVT) and ventricular fibrillation (VF) and die suddenly even after PMIs. We report a patient with KSS who developed PMVT, VF, and QT prolongation, and was treated with mexiletine and successfully managed with an implantable cardioverter defibrillator (ICD). Read More

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http://dx.doi.org/10.1016/j.ijcard.2018.12.064DOI Listing
December 2018

New atrial fibrillation diagnosed by 30-day rhythm monitoring.

Am Heart J 2018 Nov 12;209:29-35. Epub 2018 Nov 12.

Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL. Electronic address:

Background: Recent studies of patients with pacemakers and implantable cardioverter/defibrillators have shown that subclinical atrial fibrillation (AF) is common and is associated with thromboembolic risk. We sought to evaluate the frequency, characteristics, and impact of new AF diagnosed by ambulatory 30-day rhythm monitoring.

Methods: The 30-day rhythm monitoring data from January 2010 to August 2015 at our institution were reviewed. Read More

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http://dx.doi.org/10.1016/j.ahj.2018.11.003DOI Listing
November 2018

Adherence to European Society of Gastrointestinal Endoscopy recommendations of endoscopists performing small bowel capsule endoscopy in Italy.

Dig Liver Dis 2018 Dec 10. Epub 2018 Dec 10.

Division of Oncological Gastroenterology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.

Background: The European Society of Gastrointestinal Endoscopy (ESGE) has recently issued a technical review focused on small bowel capsule endoscopy (SBCE).

Aim: To compare SBCE current practice in Italy to ESGE technical recommendations.

Material And Methods: A dedicated per-centre semi-quantitative questionnaire was prepared by a group of SBCE experts. Read More

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http://dx.doi.org/10.1016/j.dld.2018.11.031DOI Listing
December 2018

[Palliative care in the cardiac setting: a consensus document of the Italian Society of Cardiology/Italian Society of Palliative Care (SIC/SICP)].

G Ital Cardiol (Rome) 2019 Jan;20(1):46-61

Presidente SIC, Struttura Cardiologica, Policlinico Universitario, Cagliari.

Palliative care is recognized as an approach that improves quality of life of patients and families facing life-threatening illnesses. This is achieved through prevention, early identification, assessment and treatment of symptoms and other psycho-social, spiritual and economic issues. Palliative care is not dependent on prognosis and can be delivered as "simultaneous care", together with disease-modifying treatments and adequate symptom relief. Read More

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http://www.giornaledicardiologia.it/articoli.php?archivio=ye
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http://dx.doi.org/10.1714/3079.30720DOI Listing
January 2019
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Iatrogenic Palpitations during Exercise in a Patient with a Dual Chamber Implantable Cardioverter-Defibrillator and Lead Dysfunction.

Int Heart J 2019 Jan 10. Epub 2019 Jan 10.

Department of Cardiovascular Medicine, Faculty of Medical Sciences, University of Fukui.

Implantable cardioverter-defibrillators (ICDs) are an effective treatment to prevent sudden cardiac death; however, lead dysfunction is an important complication during the long-term follow-up period in ICD recipients. Careful device programming is required in accordance with the individual situation in patients with lead dysfunction. We herein present a patient in whom programming to AAI triggered palpitations during exercise. Read More

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http://dx.doi.org/10.1536/ihj.18-248DOI Listing
January 2019

Implantable Cardioverter-Defibrillators are the Main Link in the Modern Concept of Sudden Cardiac Death Prevention. Problems and Prospects of the Development of the Method.

Kardiologiia 2018 Dec 25;58(12):76-84. Epub 2018 Dec 25.

Sechenov First Moscow State Medical University.

The article covers the development of the problem of sudden cardiac death prevention with the implantable cardioverter-defibrillators from the moment of creation of these devices to our days. The current concept of primary prevention of sudden cardiac death, based on the severity of manifestation of heart failure and left ventricular dysfunction, is not effective enough. Its practical application is difficult because it requires mass application of implantable defibrillators, with low predictive accuracy of these criteria in terms of development of life-threatening arrhythmias. Read More

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http://dx.doi.org/10.18087/cardio.2018.12.10197DOI Listing
December 2018
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Extended Use of the Wearable Cardioverter-Defibrillator: Which Patients Are Most Likely to Benefit?

Cardiol Res Pract 2018 29;2018:7373610. Epub 2018 Nov 29.

Arrhythmias and Electrophysiology Unit, Department of Cardiology, University Heart Center Zurich, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

Background: Wearable cardioverter-defibrillators (WCD, LifeVest, ZOLL) can protect from sudden cardiac death bridging a vulnerable period until a decision on implantable cardioverter-defibrillator (ICD) implantation can be reached. WCD is commonly used for 3 months or less. It is unknown, which patients use WCD longer and which patients are most likely to benefit from it. Read More

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http://dx.doi.org/10.1155/2018/7373610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304887PMC
November 2018

Review on sudden death risk reduction after septal reduction therapies in hypertrophic obstructive cardiomyopathy.

Heart Fail Rev 2019 Jan 8. Epub 2019 Jan 8.

Mid-German Heart Center, Department of Internal Medicine III, Division of Cardiology, Angiology and Intensive Medical Care, University Hospital Halle, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany.

Treatment of left ventricular outflow tract (LVOT) obstruction in hypertrophic obstructive cardiomyopathy (HOCM) with septal reduction, either with myectomy or alcohol septal ablation, is aiming to reduce the LVOT gradient and improve symptoms in patients who are refractory to or do not tolerate medical treatment. Apart from contributing to the evolution to heart failure, LVOT obstruction is considered a risk factor for sudden cardiac death (SCD). Both septal reduction treatments have been proven effective in reducing symptoms and seem to improve survival, which has been shown equal to the expected in the normal population. Read More

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http://dx.doi.org/10.1007/s10741-018-09767-wDOI Listing
January 2019

Impact of diurnal variations in the QRS complex and T-waves on the eligibility of subcutaneous implantable cardioverter-defibrillators.

Heart Rhythm 2019 Jan 4. Epub 2019 Jan 4.

Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan.

Background: Subcutaneous implantable cardioverter-defibrillators (S-ICDs) are an established therapy for preventing sudden cardiac death. However, a considerable number of patients still undergo inappropriate shocks even after conventional pre-implantation ECG screening.

Objective: This study aimed to elucidate the additional impact of diurnal variations in the QRS complex and T-waves of 24-h Holter monitoring on the S-ICD eligibility. Read More

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http://dx.doi.org/10.1016/j.hrthm.2019.01.004DOI Listing
January 2019

Incidence, Clinical Characteristics, and Long-term Outcome of the Dilated Phase of Hypertrophic Cardiomyopathy.

Keio J Med 2018 Dec 29. Epub 2018 Dec 29.

Department of Cardiology, Keio University School of Medicine, Tokyo, Japan.

Some patients with hypertrophic cardiomyopathy (HCM) develop systolic dysfunction, called the dilated phase of HCM (d-HCM), which is associated with increased morbidity and mortality. We conducted a retrospective study using an HCM database to clarify the incidence, clinical characteristics, and long-term outcomes of d-HCM. We analyzed an HCM cohort consisting of 434 patients (273 with apical HCM and 161 with non-apical HCM; 18 had obstructive HCM, 16 had dilated HCM, and 127 had other HCM) diagnosed by echocardiography in our hospital between 1991 and 2010. Read More

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http://dx.doi.org/10.2302/kjm.2018-0004-OADOI Listing
December 2018

Innovative Strategies in Heart Failure: Present and Future.

Arch Med Res 2018 Dec 31. Epub 2018 Dec 31.

Departamento de Cardiología, Hospital Universitario Santiago de Compostela, Santiago de Compostela, España; Instituto para el Desarrollo e Integración de la Salud, Santiago de Compostela, España; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, España. Electronic address:

Heart failure (HF) is a progressively debilitating disease that considerably decreases the life expectancy and quality of life. It has become an important area of focus since it remains one of the most common reasons for admission in patients over the age of 65. Importantly, the incidence of HF has not declined within the past 20 years, but the survival after onset has increased in younger patients and men. Read More

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http://dx.doi.org/10.1016/j.arcmed.2018.12.011DOI Listing
December 2018

Role of medical reaction in management of inappropriate ventricular arrhythmia diagnosis: the inappropriate Therapy and HOme monitoRiNg (THORN) registry.

Europace 2019 Jan 2. Epub 2019 Jan 2.

Department of Cardiology, Centre Hospitalier Universitaire La Timone, F-13385 Marseille, France.

Aims: Implantable cardioverter-defibrillators (ICDs) reduce sudden cardiac death in selected patients but inappropriate ICD shocks have been associated with increased mortality. The THORN registry aims to describe the rate of inappropriate ventricular arrhythmia diagnoses and therapies in patients followed by remote monitoring, as well as the following delay to next patient contact (DNPC).

Methods And Results: One thousand eight hundred and eighty-two patients issued from a large remote monitoring database first implanted with an ICD for primary or secondary prevention in 110 French hospitals from 2007 to 2014 constitute the THORN population. Read More

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http://dx.doi.org/10.1093/europace/euy284DOI Listing
January 2019

Cardiac implantable electronic device (CIED) infections are expensive and associated with prolonged hospitalisation: UK Retrospective Observational Study.

PLoS One 2019 2;14(1):e0206611. Epub 2019 Jan 2.

Manchester Heart Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, United Kingdom.

Background: There are limited reports outlining the financial cost of treating cardiac implantable electronic device (CIED) infection outside the United States. This study aimed to determine the average treatment cost of CIED infection in a large UK tertiary referral centre and compared costs of different treatment pathways that are recognised in the management of CIED infection (early versus delayed re-implantation).

Methods: We retrospectively analysed cost and length of stay (LOS) data for consecutive patients undergoing infected CIED extraction with cardiac resynchronization therapy (CRT-D [with defibrillator], CRT-P [with pacemaker]), implantable cardioverter-defibrillators (ICDs) and permanent pacemakers (PPMs). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206611PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314621PMC
January 2019

Electromagnetic Interference with Protocolized Electrosurgery Dispersive Electrode Positioning in Patients with Implantable Cardioverter Defibrillators.

Anesthesiology 2018 Dec 28. Epub 2018 Dec 28.

From the Department of Anesthesiology and Perioperative Medicine (P.M.S., M.M.T., M.J.M., V.S., I.H., R.B.A., A.B., N.A.) the Knight Cardiovascular Institute (C.A.H., P.M.J., T.A.D., E.C.S.) Oregon Health and Science University, Portland, Oregon; the School of Public Health, Oregon Health and Science University and Portland State University, Portland, Oregon (N.D.Y.) Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin (E.K.).

What We Already Know About This Topic: Electromagnetic interference from monopolar electrosurgery may disrupt implantable cardioverter defibrillators.Current management recommendations by the American Society of Anesthesiologists and Heart Rhythm Society are based on expert clinical opinion since there is a paucity of data regarding the risk of electromagnetic interference to implantable cardioverter defibrillators during surgery.

What This Article Tells Us That Is New: With protocolized electrosurgery dispersive electrode positioning in patients with implantable cardioverter defibrillators, the risk of clinically meaningful electromagnetic interference was 7% in above-the-umbilicus noncardiac surgery and 0% in below-the-umbilicus surgery. Read More

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http://dx.doi.org/10.1097/ALN.0000000000002571DOI Listing
December 2018
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Use of Administrative Data to Monitor Cardiac Implantable Electronic Device Complications.

Can J Cardiol 2019 Jan 13;35(1):100-103. Epub 2018 Nov 13.

Division of Cardiology, QEII Health Sciences Centre, Halifax, Nova Scotia, Canada.

Cardiac implantable electronic devices (CIEDs) are increasingly used in the Canadian population, because of expanding indications and an aging population. Device-related complications are a source of morbidity and mortality. There is currently no comprehensive monitoring strategy of CIED-related complications in Canada. Read More

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http://dx.doi.org/10.1016/j.cjca.2018.10.018DOI Listing
January 2019

A comparison of anti-arrhythmic efficacy of carvedilol vs metoprolol succinate in patients with implantable cardioverter-defibrillators.

Clin Cardiol 2018 Dec 27. Epub 2018 Dec 27.

Division of Cardiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

Background: The effects of carvedilol and metoprolol succinate on appropriate and inappropriate implantable cardioverter defibrillator (ICD) therapy in patients with heart failure with reduced ejection fraction (HFrEF) are not fully understood.

Hypothesis: The hypothesis of our study is possible carvedilol superiority over metoprolol in patients with ICD.

Methods: All patients with ICD registered to a single device clinic between 1/2012 and 6/2017 (n = 569) were identified. Read More

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http://dx.doi.org/10.1002/clc.23144DOI Listing
December 2018

The Australian and New Zealand Cardiac Implantable Electronic Device Survey: Calendar Year 2017.

Heart Lung Circ 2018 Dec 11. Epub 2018 Dec 11.

Christchurch Hospital, Christchurch, New Zealand.

Background: A cardiac implantable electronic device (CIED) survey was undertaken in Australia and New Zealand for calendar year 2017 and involved pacemakers (PMs) and implantable cardioverter-defibrillators (ICDs).

Results And Conclusions: For 2017, there were 17,971 (15,203 in 2013) new PMs sold in Australia and 1,811 (1,641 in 2013) implanted in New Zealand. The number of new PM implants per million population was 745 for Australia (652 in 2013) and 384 for New Zealand (367 in 2013). Read More

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http://dx.doi.org/10.1016/j.hlc.2018.11.018DOI Listing
December 2018

Phase I/II Trial of Electrophysiology-Guided Noninvasive Cardiac Radioablation for Ventricular Tachycardia.

Circulation 2019 Jan;139(3):313-321

Department of Internal Medicine, Cardiovascular Division (K.M.S.M., D.H.C., M.F., A.N., T.W.S., P.S.C.), Washington University, St Louis, MO.

Background: Case studies have suggested the efficacy of catheter-free, electrophysiology-guided noninvasive cardiac radioablation for ventricular tachycardia (VT) using stereotactic body radiation therapy, although prospective data are lacking.

Methods: We conducted a prospective phase I/II trial of noninvasive cardiac radioablation in adults with treatment-refractory episodes of VT or cardiomyopathy related to premature ventricular contractions (PVCs). Arrhythmogenic scar regions were targeted by combining noninvasive anatomic and electric cardiac imaging with a standard stereotactic body radiation therapy workflow followed by delivery of a single fraction of 25 Gy to the target. Read More

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331281PMC
January 2019

Combined mechanical mitral valve replacement and transmitral myectomy for hypertrophic obstructive cardiomyopathy treatment: An experience of over 20 years.

J Cardiol 2018 Dec 21. Epub 2018 Dec 21.

Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.

Background: Although transaortic septal myectomy (TASM) is recognized as a standard procedure for treating hypertrophic obstructive cardiomyopathy (HOCM), occasionally the left ventricle (LV) intracavitary gradient remains postoperatively because of this technically demanding procedure. Mitral valve replacement (MVR) is sometimes chosen as an alternative option, but data on its long-term outcomes are lacking.

Methods And Results: Between 1991 and 2016, 29 patients [age, 14-82 (mean 58. Read More

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http://dx.doi.org/10.1016/j.jjcc.2018.12.012DOI Listing
December 2018

Mechanisms and management of inappropriate therapy in subcutaneous implantable cardioverter defibrillators.

J Cardiovasc Electrophysiol 2018 Dec 21. Epub 2018 Dec 21.

Electrophysiology and Arrhythmia Service, Cardiology Division, Department of Medicine, Boston Medical Center, Boston, Massachusetts.

Subcutaneous implantable cardioverter defibrillators (S-ICDs) provide reliable defibrillation and have enhanced supraventricular tachycardia discrimination and fewer infection rates compared with traditional transvenous systems. However, inappropriate shocks remain a frequent problem. Herein, we review the various mechanisms of these inappropriate therapies, some of which are unique to S-ICDs, and propose an algorithm for preventing recurrences. Read More

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http://dx.doi.org/10.1111/jce.13831DOI Listing
December 2018

Effectiveness of Implantable DEfibrillators Alert Systems: comparison between audible and vibratory alert: IDEAS study.

J Cardiovasc Med (Hagerstown) 2018 Dec 19. Epub 2018 Dec 19.

Cardiology Unit, 'Card. G. Panico' Hospital, Tricase.

Introduction: Implantable cardioverter-defibrillator (ICD) alarm systems are an important means of monitoring device functioning. The aim of this study was to compare the ability of patients with sense two types of device alert systems: an audible alert and a vibratory alarm.

Methods: The ability to recognize the alarms was assessed in three alarm tests performed in a series of consecutive ICD patients enrolled during routine outpatient device follow-up. Read More

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http://dx.doi.org/10.2459/JCM.0000000000000745DOI Listing
December 2018

Amiodarone is associated with adverse outcomes in patients with sustained ventricular arrhythmias upgraded to cardiac resynchronization therapy-defibrillators.

J Cardiovasc Electrophysiol 2018 Dec 21. Epub 2018 Dec 21.

University of Pittsburgh Heart and Vascular Institute, Pittsburgh, Pennsylvania.

Introduction: Amiodarone reduces recurrent ventricular tachyarrhythmias (VTA) but may worsen cardiovascular outcomes in heart failure (HF) patients. Cardiac resynchronization therapy (CRT) may also be antiarrhythmic. When patients with prior sustained VTA are upgraded to CRT defibrillators (CRT-D) from conventional implantable cardioverter-defibrillators (ICDs), should concomitant amiodarone be continued or is CRT's antiarrhythmic potential sufficient?

Methods And Results: We identified 67 patients from a prospective CRT registry with spontaneous sustained VTA, New York Heart Association (NYHA) II-IV HF, and left bundle-branch block (LBBB) who were upgraded to CRT defibrillators from conventional ICDs. Read More

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http://dx.doi.org/10.1111/jce.13828DOI Listing
December 2018

Pregnancy and delivery in woman with implantable cardioverter-defibrillator: what we should know.

Pan Afr Med J 2018 30;30:236. Epub 2018 Jul 30.

Obstsetric Department, Farhat Hached Hospital, Sousse, Tunisia.

We report the observation of a 25-year-old pregnant patient of 39 weeks of amenorrhea proposed for elective cesarean section. This patient suffers from hypertrophic cardiomyopathy since the age of 12. She has an implantable cardioverter defibrillator (ICD). Read More

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http://dx.doi.org/10.11604/pamj.2018.30.236.9995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295306PMC
January 2019

Moving Beyond the Hospital.

Circulation 2018 Nov;138(20):2169-2171

Department of Medicine, Massachusetts General Hospital, Boston (C.P.M., Z.S.), Department of Health Care Policy (Z.S.), Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036391DOI Listing
November 2018

Is Time From Last Hospitalization for Heart Failure to Placement of a Primary Prevention Implantable Cardioverter-Defibrillator Associated With Patient Outcomes?

Circulation 2018 Dec;138(24):2787-2797

Division of Cardiology, Duke University Medical Center, Durham, NC (D.J.F., M.F., A.F.H., S.M.A.-K.).

Background: Landmark studies have demonstrated the safety and efficacy of implantable cardioverter-defibrillators (ICDs) in selected stable ambulatory patients with heart failure (HF) with a reduced ejection fraction receiving optimal medical therapy. It is not known whether a recent hospitalization for HF before ICD placement is associated with subsequent outcomes.

Methods: A post hoc analysis was performed of Medicare beneficiaries enrolled in the National Cardiovascular Data Registry's ICD Registry with a known diagnosis of HF and an ejection fraction ≤35% underdoing a new ICD placement for primary prevention. Read More

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035627DOI Listing
December 2018

Facility-Level Variation and Clinical Outcomes in Use of Cardiac Resynchronization Therapy With and Without an Implantable Cardioverter-Defibrillator.

Circ Cardiovasc Qual Outcomes 2018 Dec;11(12):e004763

Harvard Medical School, Boston, MA (D.B.K., S.-L.T.N., R.V., L.A.H.).

Background: Little is known about real-world facility-level preferences for cardiac resynchronization therapy devices with (CRT-D) and without (CRT-P) defibrillator backup. We quantify this variation at the facility level and exploit this variation to compare outcomes of patients receiving these 2 devices.

Methods And Results: Claims data from fee-for-service Medicare beneficiaries were used to identify new CRT-P and CRT-D implants, 2006 to 2012. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.118.004
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http://dx.doi.org/10.1161/CIRCOUTCOMES.118.004763DOI Listing
December 2018
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Cognitive performance in patients with implantable cardioverter defibrillators: Associations with objective sleep duration, age and anxiety.

J Sleep Res 2018 Dec 13:e12810. Epub 2018 Dec 13.

Department of Psychiatry, University of Missouri, Columbia, Missouri.

Sleep disturbance and anxiety are highly prevalent in patients with implantable cardiac defibrillators (ICDs). There is limited research, however, on the associations between cognitive performance and sleep parameters, age and anxiety. Forty-one patients with ICDs and self-reported sleep disturbance completed 14 days of actigraphy (M  = 60. Read More

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http://dx.doi.org/10.1111/jsr.12810DOI Listing
December 2018
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3.347 Impact Factor

Use of the Metal Deletion Technique for Radiotherapy Planning in Patients with Cardiac Implantable Devices.

Klin Onkol 2018 ;31(6):434-438

Background: The number of cancer patients with cardiac implantable electronic devices receiving radiotherapy is increasing. Irradiation of such patients can cause malfunctions in pacemakers and implantable cardioverter-defibrillators. In this respect, it is necessary to make a proper irradiation plan for such cancer patients to minimize the dose received by both cardiac devices and pacing leads. Read More

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http://dx.doi.org/10.14735/amko2018434DOI Listing
January 2018

Single-brand dual-chamber discriminators to prevent inappropriate shocks in patients implanted with prophylactic implantable cardioverter defibrillators: a propensity-weighted comparison of single- and dual-chamber devices.

J Interv Card Electrophysiol 2018 Dec 6. Epub 2018 Dec 6.

Cardiology Department, Hospital Universitario Infanta Leonor, Gran Vía del Este, 28030, Madrid, Spain.

Purpose: Comparisons of the efficacy of dual- vs. single-chamber implantable cardioverter defibrillators (ICDs) in preventing inappropriate shocks have had contradictory results. We investigated whether dual-chamber devices have a lower risk of inappropriate shocks and the specific role of supraventricular tachycardia (SVT) discriminators. Read More

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http://dx.doi.org/10.1007/s10840-018-0494-0DOI Listing
December 2018
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Health-Related Quality of Life and Psychological Adjustment of Children and Adolescents with Pacemakers and Implantable Cardioverter Defibrillators: A Systematic Review.

Pediatr Cardiol 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiology, Pediatric Heart Centre, University Children's Hospital Zurich, Steinwiesstr. 75, 8032, Zurich, Switzerland.

The absence of cardiac symptoms, the improved exercise tolerance and the increased life expectancy are the advantages of a successful cardiac device therapy. Nevertheless, the fact of a lifelong device dependency, the inherent possibility of device malfunction and the progression of the underlying heart disease may impact the health-related quality of life (HRQoL) and the psychological adjustment of these individuals. To date, an overview of findings on these topics is lacking. Read More

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http://dx.doi.org/10.1007/s00246-018-2038-xDOI Listing
December 2018

Implantable cardiac defibrillators for people with non-ischaemic cardiomyopathy.

Cochrane Database Syst Rev 2018 Dec 8;12:CD012738. Epub 2018 Dec 8.

Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

Background: There is evidence that implantable cardioverter-defibrillator (ICD) for primary prevention in people with an ischaemic cardiomyopathy improves survival rate. The evidence supporting this intervention in people with non-ischaemic cardiomyopathy is not as definitive, with the recently published DANISH trial finding no improvement in survival rate. A systematic review of all eligible studies was needed to evaluate the benefits and harms of using ICDs for primary prevention in people with non-ischaemic cardiomyopathy. Read More

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http://doi.wiley.com/10.1002/14651858.CD012738.pub2
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http://dx.doi.org/10.1002/14651858.CD012738.pub2DOI Listing
December 2018
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Remote monitoring of implantable cardioverter defibrillators: Patient experiences and preferences for follow-up.

Pacing Clin Electrophysiol 2018 Dec 10. Epub 2018 Dec 10.

Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.

Background: Patient satisfaction with remote patient monitoring (RPM) of implantable cardioverter defibrillators (ICDs) seems to be high, yet knowledge on long-term patient experiences is limited. The European REMOTE-CIED study explored patients' experiences with RPM, examined patient's preferences for ICD follow-up, and identified determinants of patient's preferences in the first 2 years postimplantation.

Methods: European heart failure patients (N = 300; median age = 66 years [interquartile range (IQR) = 59-73], and 22% female) with a first-time ICD received a Boston Scientific LATITUDE RPM system (Marlborough, MA, USA) and had scheduled in-clinic follow-ups once a year. Read More

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http://dx.doi.org/10.1111/pace.13574DOI Listing
December 2018
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Remote monitoring of implantable cardioverter defibrillators: Aligning patient preferences and provider recommendations.

Authors:
Lindsey Rosman

Pacing Clin Electrophysiol 2018 Dec 10. Epub 2018 Dec 10.

Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1111/pace.13572DOI Listing
December 2018

Contemporary Management of Heart Failure in the Elderly.

Drugs Aging 2018 Dec 11. Epub 2018 Dec 11.

British Heart Foundation Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK.

The foundation of the treatment of heart failure with reduced ejection fraction is a number of pharmacotherapies shown to reduce morbidity and mortality in large randomised multinational clinical trials. These include angiotensin converting enzyme inhibitors, angiotensin receptor blockers, beta-blockers, mineralocorticoid receptor antagonists, and more recently, a combined angiotensin receptor blocker neprilysin inhibitor, sacubitril/valsartan. In select cases, digoxin, ivabradine and hydralazine with isosorbide dinitrate have a role to play in the treatment of heart failure with reduced ejection fraction. Read More

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http://link.springer.com/10.1007/s40266-018-0625-4
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http://dx.doi.org/10.1007/s40266-018-0625-4DOI Listing
December 2018
4 Reads

Clinical outcome in patients with implantable cardioverter-defibrillator and cancer: a nationwide study.

Europace 2018 Dec 7. Epub 2018 Dec 7.

Department of Cardiology, Herlev-Gentofte University Hospitals, Kildegårdsvej 28, Copenhagen, 2900 Hellerup, Denmark.

Aims: Patients with cancer are insufficiently represented in randomized clinical trials investigating efficacy of implantable cardioverter-defibrillators (ICDs). We aimed to describe outcomes in patients with a pre-existing diagnosis of cancer at time of ICD implantation.

Methods And Results: We utilized Danish nationwide registries to identify primary and secondary prevention ICD implantations from 2007 to 2012. Read More

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http://dx.doi.org/10.1093/europace/euy268DOI Listing
December 2018

Quantitative Regular Expressions for Arrhythmia Detection.

IEEE/ACM Trans Comput Biol Bioinform 2018 Dec 10. Epub 2018 Dec 10.

Implantable medical devices are safety-critical systems whose incorrect operation can jeopardize a patient's health, and whose algorithms must meet tight platform constraints like memory consumption and runtime. In particular, we consider here the case of implantable cardioverter defibrillators, where peak detection algorithms and various others discrimination algorithms serve to distinguish fatal from non-fatal arrhythmias in a cardiac signal. Motivated by the need for powerful formal methods to reason about the performance of arrhythmia detection algorithms, we show how to specify all these algorithms using Quantitative Regular Expressions (QREs). Read More

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https://ieeexplore.ieee.org/document/8570818/
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http://dx.doi.org/10.1109/TCBB.2018.2885274DOI Listing
December 2018
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A Population-Based Study of Adherence to Guideline Recommendations and Appropriate-Use Criteria for Implantable Cardioverter Defibrillators.

Can J Cardiol 2018 Dec 24;34(12):1677-1681. Epub 2018 Aug 24.

Mazankowski Alberta Heart Institute, University of Alberta, Division of Cardiology, Edmonton, Alberta, Canada. Electronic address:

Studies evaluating physician adherence to guideline recommendations for implantable cardioverter defibrillator (ICD) therapy are sparse, and none exist for the application of appropriate-use criteria (AUC) in clinical practice. As part of a quality improvement initiative, a review of all ICD procedures was performed from January 1, 2015 to December 31, 2016 in Alberta, Canada, to evaluate the proportion of patients receiving appropriate ICD therapy and to identify reasons for nonadherence. Our device-implant process involves an electrophysiologist or implanting cardiologist evaluation, reminders of ICD eligibility criteria on the device requisition, and peer-review consensus. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0828282X183106
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http://dx.doi.org/10.1016/j.cjca.2018.08.030DOI Listing
December 2018
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Evaluation of the safety of users of active implantable medical devices (AIMD) in the working environment in terms of exposure to electromagnetic fields - Practical approach to the requirements of European Directive 2013/35/EU.

Int J Occup Med Environ Health 2018 12 5;31(6):795-808. Epub 2018 Nov 5.

Central Institute for Labour Protection - National Research Institute, Warszawa, Poland (Laboratory of Electromagnetic Hazards).

Objectives: Electromagnetic fields (EMF) may cause malfunctions in electronic devices, in particular in active implantable medical devices (AIMD), along with discomfort or health hazards to users. The use of AIMD by workers is increasing (especially cardiac pacemakers, implantable cardioverter defibrillators and wearable insulin infusion pumps). Electromagnetic fields may be much stronger in the working environment than applied in basic immunity tests of AIMD (based on EN 60601- 1-2:2015 and EN 50527-1:2016). Read More

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http://www.journalssystem.com/ijomeh/AN-EVALUATION-OF-THE-SA
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http://dx.doi.org/10.13075/ijomeh.1896.00783DOI Listing
December 2018
9 Reads

Safety of Sports for Young Patients With Implantable Cardioverter-Defibrillators.

Circ Arrhythm Electrophysiol 2018 Nov;11(11):e006305

Yale University School of Medicine, New Haven, CT (J.D., C.B., L.S., F.L., R.J.L.).

Background: Despite safety concerns, many young patients with implantable cardioverter-defibrillators (ICDs) participate in sports. We undertook a prospective, multinational registry to determine the incidence of serious adverse events because of sports participation. The primary end points were death or resuscitated arrest during sports or injury during sports because of arrhythmia or shock. Read More

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http://dx.doi.org/10.1161/CIRCEP.118.006305DOI Listing
November 2018
6 Reads

Predicting electrical storms by remote monitoring of implantable cardioverter-defibrillator patients using machine learning.

Europace 2018 Nov 30. Epub 2018 Nov 30.

Department of Computer Science, University of Copenhagen, Universitetsparken 5, Copenhagen 2100, Denmark.

Aims: Electrical storm (ES) is a serious arrhythmic syndrome that is characterized by recurrent episodes of ventricular arrhythmias. Electrical storm is associated with increased mortality and morbidity despite the use of implantable cardioverter-defibrillators (ICDs). Predicting ES could be essential; however, models for predicting this event have never been developed. Read More

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http://dx.doi.org/10.1093/europace/euy257DOI Listing
November 2018

Cardiac Sarcoidosis.

Am J Cardiol 2019 Feb 6;123(3):513-522. Epub 2018 Nov 6.

Cardiovascular Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Clinical and subclinical cardiac sarcoidosis (CS) remains diagnostically challenging as the sensitivity and specificity of the diagnostic modalities are limited. The Japanese Ministry of Health and Welfare criteria and the Heart Rhythm Society expert consensus statement on CS are the most common guidelines used to diagnose CS. However, they are mostly based on expert opinions and lack clinical trial validation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029149183203
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http://dx.doi.org/10.1016/j.amjcard.2018.10.021DOI Listing
February 2019
5 Reads

Implantable cardioverter-defibrillator therapies are associated with increased incidence of depression and mortality.

Turk Kardiyol Dern Ars 2018 12;46(8):742

Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

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http://dx.doi.org/10.5543/tkda.2018.01361DOI Listing
December 2018

Differences in amiodarone efficacy in relation to ejection fraction and basal rhythm in patients with implantable cardioverter defibrillators.

J Electrocardiol 2018 Nov - Dec;51(6):1111-1115. Epub 2018 Oct 8.

Department of Cardiology, Nishinomiya Municipal Central Hospital, Nishinomiya, Japan.

Background: Atrial fibrillation (AF) and ventricular arrhythmias (VAs) are associated with increased morbidity and mortality. However, data are lacking concerning the association of AF and VAs. This study aimed to clarify the association between AF and VAs and to investigate the effect of amiodarone on the incidence of VAs in patients with implantable cardioverter defibrillators (ICDs). Read More

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http://dx.doi.org/10.1016/j.jelectrocard.2018.10.083DOI Listing
October 2018
1 Read

Electrical Stun Gun and Modern Implantable Cardiac Stimulators.

Health Phys 2019 Jan;116(1):18-26

Italian National Institute of Health, Rome, Italy.

The aim of the study is to investigate systematically the possible interactions between two types of stun guns and last-generation pacemakers and implantable defibrillators. Experimental measurements were performed on pacemakers and implantable defibrillators from five leading manufacturers, considering the effect of stun gun dart positioning, sensing modality, stun gun shock duration, and defibrillation energy level. More than 300 measurements were collected. Read More

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http://dx.doi.org/10.1097/HP.0000000000000942DOI Listing
January 2019
2 Reads

Ventricular tachycardia prediction in patients with implantable cardioverter-defibrillators for primary prevention of sudden cardiac death.

Indian Pacing Electrophysiol J 2018 Nov 25. Epub 2018 Nov 25.

Arrhythmology Department, National Almazov Medical Research Centre, 2 Akkuratova St., St. Petersburg, 197341, Russian Federation. Electronic address:

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http://dx.doi.org/10.1016/j.ipej.2018.11.011DOI Listing
November 2018
1 Read